YOD1

Protein ubiquitination controls many intracellular processes, including cell cycle progression, transcriptional activation, and signal transduction. This dynamic process, involving ubiquitin conjugating enzymes and deubiquitinating enzymes, adds and removes ubiquitin. Deubiquitinating enzymes are cysteine proteases that specifically cleave ubiquitin from ubiquitin-conjugated protein substrates. The protein encoded by this gene belongs to a DUB subfamily characterized by an ovarian tumor (OTU) domain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]

Description

YOD1 deubiquitinase

Tissue specificity

Tissue enhanced (bone marrow)

Subcell location

Nucleoplasm, Plasma membrane, Cytosol

Predicted location

Intracellular

Protein family

Enzymes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

1 (207043849 - 207052980)

Ensembl ID

ENSG00000180667  (ver. 103.38)

Orthologs

Mouse Yod1: ENSMUSG00000046404

UniProt

Q5VVQ6

neXtProt

NX_Q5VVQ6

Human splice variants
Mouse splice variants

Protein structure