Tissue expression
Cell line expression
Protein structure
PFKFB2
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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NSJ Bioreagents | RQ6432 | Polyclonal |
WB
EL
ICC
IHC
FC
|
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Proteintech Group | 17838-1-AP | 5 references | Polyclonal |
WB
EL
IHC
|
|
Biorbyt | orb745960 | Polyclonal |
WB
EL
ICC
IHC
FC
|
||
Novus Biologicals | NBP1-45238 | 1 references | Polyclonal |
WB
EL
IHC
|
|
Boster Biological Technology | A05977 | Polyclonal |
WB
EL
ICC
FC |
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Supportive data in Antibodypedia
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Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider