BS6313

antibody from Bioworld Technology, Inc

Targeting: SMYD2 HSKM-B, KMT3C, ZMYND14

Immunohistochemistry

Antibody data

Submit

Validation data

Product number: BS6313 - Provider product page
Provider: Bioworld Technology, Inc
Product name: SMYD2 polyclonal antibody
Antibody type: Polyclonal
Antigen: Recombinant full length Human SMYD2.
Description: SMYD2 (SET and MYND domain containing 2), also known as KMT3C, HSKM-B or ZMYND14, is a 433 amino acid protein that contains one SET domain and one MYND-type zinc finger. Expressed at high levels in liver, heart, kidney, ovary and brain, SMYD2 functions as a lysine methyltransferase that, via methylation of p53, may play a role in repressing p53-mediated transcriptional regulation. The gene encoding MSYD2 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson£ªs disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Vial size: 100ul
Concentration: 1 mg/ml
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SMYD2 protein structure - BS6313 shown in red.