ABIN351088

antibody from antibodies-online

Targeting: RHOU ARHU, CDC42L1, DJ646B12.2, fJ646B12.2, FLJ10616, hG28K, WRCH-1, WRCH1

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN351088

Provider

antibodies-online

Proper citation

Antibodies-Online Cat#ABIN351088, RRID:AB_10785603

Product name

anti-Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3) (Cytoplasmic Domain) antibody

Antibody type

Polyclonal

Antigen

A synthetic peptide from the cytoplasmic domain of human TrkC (Trk-C, NTRK3, NT-3 growth factor receptor, GP145-TrkC) conjugated to an immunogenic carrier protein was used as the antigen. The antigen is homologous in rat and mouse.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

Cytoplasmic Domain

Vial size

100 μL

Storage

Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability.

Handling

Avoid freeze and thaw cycles.

References

Submitted references

Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain.

Ballif BA, Carey GR, Sunyaev SR, Gygi SP
Journal of proteome research 2008 Jan;7(1):311-8

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Crystal structures of the neurotrophin-binding domain of TrkA, TrkB and TrkC.

Ultsch MH, Wiesmann C, Simmons LC, Henrich J, Yang M, Reilly D, Bass SH, de Vos AM
Journal of molecular biology 1999 Jul 2;290(1):149-59

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Identification and characterization of novel substrates of Trk receptors in developing neurons.

Qian X, Riccio A, Zhang Y, Ginty DD
Neuron 1998 Nov;21(5):1017-29

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Human trks: molecular cloning, tissue distribution, and expression of extracellular domain immunoadhesins.

Shelton DL, Sutherland J, Gripp J, Camerato T, Armanini MP, Phillips HS, Carroll K, Spencer SD, Levinson AD
The Journal of neuroscience : the official journal of the Society for Neuroscience 1995 Jan;15(1 Pt 2):477-91

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Molecular cloning of the cDNA for human TrkC (NTRK3), chromosomal assignment, and evidence for a splice variant.

McGregor LM, Baylin SB, Griffin CA, Hawkins AL, Nelkin BD
Genomics 1994 Jul 15;22(2):267-72

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The rat trkC locus encodes multiple neurogenic receptors that exhibit differential response to neurotrophin-3 in PC12 cells.

Tsoulfas P, Soppet D, Escandon E, Tessarollo L, Mendoza-Ramirez JL, Rosenthal A, Nikolics K, Parada LF
Neuron 1993 May;10(5):975-90

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Alternative forms of rat TrkC with different functional capabilities.

Valenzuela DM, Maisonpierre PC, Glass DJ, Rojas E, Nuñez L, Kong Y, Gies DR, Stitt TN, Ip NY, Yancopoulos GD
Neuron 1993 May;10(5):963-74

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Molecular cloning of rat trkC and distribution of cells expressing messenger RNAs for members of the trk family in the rat central nervous system.

Merlio JP, Ernfors P, Jaber M, Persson H
Neuroscience 1992 Dec;51(3):513-32