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- References [4]
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- Product number
- ABIN499748 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Disrupted in Schizophrenia 1 (DISC1) antibody
- Antibody type
- Polyclonal
- Antigen
- DISC1 antibody was raised against a 18 amino acid peptide from near the center of humanDISC1. (ABIN499747)
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Store the antibody undiluted at 2-8°C. Shelf life: one year from despatch.
Submitted references Disrupted-In-Schizophrenia 1 regulates integration of newly generated neurons in the adult brain.
DISC1 regulates the transport of the NUDEL/LIS1/14-3-3epsilon complex through kinesin-1.
DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation.
Disruption of two novel genes by a translocation co-segregating with schizophrenia.
Duan X, Chang JH, Ge S, Faulkner RL, Kim JY, Kitabatake Y, Liu XB, Yang CH, Jordan JD, Ma DK, Liu CY, Ganesan S, Cheng HJ, Ming GL, Lu B, Song H
Cell 2007 Sep 21;130(6):1146-58
Cell 2007 Sep 21;130(6):1146-58
DISC1 regulates the transport of the NUDEL/LIS1/14-3-3epsilon complex through kinesin-1.
Taya S, Shinoda T, Tsuboi D, Asaki J, Nagai K, Hikita T, Kuroda S, Kuroda K, Shimizu M, Hirotsune S, Iwamatsu A, Kaibuchi K
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007 Jan 3;27(1):15-26
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007 Jan 3;27(1):15-26
DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation.
Morris JA, Kandpal G, Ma L, Austin CP
Human molecular genetics 2003 Jul 1;12(13):1591-608
Human molecular genetics 2003 Jul 1;12(13):1591-608
Disruption of two novel genes by a translocation co-segregating with schizophrenia.
Millar JK, Wilson-Annan JC, Anderson S, Christie S, Taylor MS, Semple CA, Devon RS, St Clair DM, Muir WJ, Blackwood DH, Porteous DJ
Human molecular genetics 2000 May 22;9(9):1415-23
Human molecular genetics 2000 May 22;9(9):1415-23
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of DISC1 in SK-N-SH cell lysate with AP30292PU-N DISC1 antibody at (A) 0.5, (B) 1 and (C) 2 ?g/ml.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunocytochemistry of DISC1 in HeLa cells with AP30292PU-N DISC1 antibody at 5 ?g/ml.
