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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [5]
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- Western blot [3]
- Immunocytochemistry [2]
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- Product number
- GTX109891 - Provider product page
- Provider
- GeneTex
- Proper citation
- GeneTex Cat#GTX109891, RRID:AB_11172320
- Product name
- Exonuclease 1 antibody
- Antibody type
- Polyclonal
- Reactivity
- Human, Mouse
- Host
- Rabbit
Submitted references SMYD3 Promotes Homologous Recombination via Regulation of H3K4-mediated Gene Expression.
DNA damage tolerance pathway involving DNA polymerase ι and the tumor suppressor p53 regulates DNA replication fork progression.
Quantitation of DNA double-strand break resection intermediates in human cells.
Microhomology-mediated End Joining and Homologous Recombination share the initial end resection step to repair DNA double-strand breaks in mammalian cells.
DNA-dependent protein kinase regulates DNA end resection in concert with Mre11-Rad50-Nbs1 (MRN) and ataxia telangiectasia-mutated (ATM).
Chen YJ, Tsai CH, Wang PY, Teng SC
Scientific reports 2017 Jun 19;7(1):3842
Scientific reports 2017 Jun 19;7(1):3842
DNA damage tolerance pathway involving DNA polymerase ι and the tumor suppressor p53 regulates DNA replication fork progression.
Hampp S, Kiessling T, Buechle K, Mansilla SF, Thomale J, Rall M, Ahn J, Pospiech H, Gottifredi V, Wiesmüller L
Proceedings of the National Academy of Sciences of the United States of America 2016 Jul 26;113(30):E4311-9
Proceedings of the National Academy of Sciences of the United States of America 2016 Jul 26;113(30):E4311-9
Quantitation of DNA double-strand break resection intermediates in human cells.
Zhou Y, Caron P, Legube G, Paull TT
Nucleic acids research 2014 Feb;42(3):e19
Nucleic acids research 2014 Feb;42(3):e19
Microhomology-mediated End Joining and Homologous Recombination share the initial end resection step to repair DNA double-strand breaks in mammalian cells.
Truong LN, Li Y, Shi LZ, Hwang PY, He J, Wang H, Razavian N, Berns MW, Wu X
Proceedings of the National Academy of Sciences of the United States of America 2013 May 7;110(19):7720-5
Proceedings of the National Academy of Sciences of the United States of America 2013 May 7;110(19):7720-5
DNA-dependent protein kinase regulates DNA end resection in concert with Mre11-Rad50-Nbs1 (MRN) and ataxia telangiectasia-mutated (ATM).
Zhou Y, Paull TT
The Journal of biological chemistry 2013 Dec 27;288(52):37112-25
The Journal of biological chemistry 2013 Dec 27;288(52):37112-25
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Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Sample (30 ?g of whole cell lysate) A: Jurkat 7.5% SDS PAGE GTX109891 diluted at 1:1000 The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Sample (50 ?g of whole cell lysate) A: mouse thymus 7.5% SDS PAGE GTX109891 diluted at 1:1000 The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Various whole cell extracts (30 ?g) were separated by 5% SDS-PAGE, and the membrane was blotted with Exonuclease 1 antibody (GTX109891) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using Exonuclease 1(GTX109891) antibody at 1:500 dilution.
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Exonuclease 1 antibody detects Exonuclease 1 protein at nucleus by immunofluorescent analysis.Sample: HCT116 cells were fixed in 4% paraformaldehyde at RT for 15 min.Green: Exonuclease 1 protein stained by Exonuclease 1 antibody (GTX109891) diluted at 1:1000.Red: phalloidin, a cytoskeleton marker, stained by phalloidin (invitrogen, A12380) diluted at 1:200.Blue: Hoechst 33342 staining.
