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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- PAB16535 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB16535, RRID:AB_10680225
- Product name
- TICAM2 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of TICAM2.
- Antigen sequence
EDDTDEALRVQNLLQDD- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Absence of TRAM restricts Toll-like receptor 4 signaling in vascular endothelial cells to the MyD88 pathway.
LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF.
TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway.
Harari OA, Alcaide P, Ahl D, Luscinskas FW, Liao JK
Circulation research 2006 May 12;98(9):1134-40
Circulation research 2006 May 12;98(9):1134-40
LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF.
Fitzgerald KA, Rowe DC, Barnes BJ, Caffrey DR, Visintin A, Latz E, Monks B, Pitha PM, Golenbock DT
The Journal of experimental medicine 2003 Oct 6;198(7):1043-55
The Journal of experimental medicine 2003 Oct 6;198(7):1043-55
TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway.
Yamamoto M, Sato S, Hemmi H, Uematsu S, Hoshino K, Kaisho T, Takeuchi O, Takeda K, Akira S
Nature immunology 2003 Nov;4(11):1144-50
Nature immunology 2003 Nov;4(11):1144-50
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of TICAM2 in the (Lane 1) absence and (Lane 2) presence of immunizing peptide in human lung, (Lane 3) mouse lung and (Lane 4) rat lung lysate using TICAM2 polyclonal antibody (Cat # PAB16535) at 1 ug/mL . Goat anti-rabbit Ig HRP secondary antibody and PicoTect ECL substrate solution were used for this test.
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of TICAM2 in formalin-fixed, paraffin-embedded human brain tissue using an isotype control (top left) and TICAM2 polyclonal antibody (Cat # PAB16535) (bottom left, right) at 5 ug/mL .
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
