FNab00840

antibody from FineTest Biotech

Targeting: BCL2 Bcl-2, PPP1R50

Western blot

ELISA

Immunoprecipitation

Immunohistochemistry

Antibody data

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Validation data

Product number: FNab00840 - Provider product page
Provider: FineTest Biotech
Product name: BCL2 antibody
Antibody type: Monoclonal
Antigen: Recombinant protein fragment
Description: Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor(APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release(PubMed:17418785).
Reactivity: Human
Host: Mouse
Conjugate: Unconjugated
Antigen sequence: B-cell CLL/lymphoma 2
Epitope: IgG2a
Isotype: IgG
Antibody clone number: 8A10
Vial size: 100¦Ìg
Concentration: Protein A+G purification
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

BCL2 protein structure - FNab00840 shown in red.