CABT-B10401

antibody from Creative Diagnostics

Targeting: HIRA DGCR1, TUP1, TUPLE1

Western blot (Recommended by provider)

Antibody Data

Product number

CABT-B10401

Provider

Creative Diagnostics

Product name

Mouse anti-Human HIRA monoclonal antibody, clone XD2203I22

Antibody type

Monoclonal

Description

This gene encodes a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this gene in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochomatin. This gene plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate gene in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development. [provided by RefSeq, Jul 2008]

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

XD2203I22

Vial size

100 _l

Storage

Store at -20°C for long-term storage. Store at 2-8°C for up to one month. Avoid freeze/thaw cycles.