BS8339

antibody from Bioworld Technology, Inc
Targeting: NFS1 IscS, NifS
Provider product page for BS8339
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS8339 - Provider product page
Provider
Bioworld Technology, Inc
Product name
NFS1 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human NFS1.
Description
NFS1 (nitrogen fixation 1), also known as NIFS or IscS (cysteine desulfurase), is a member of the class V pyridoxal-phosphate-dependent aminotransferase family. It localizes to the cytoplasm or mitochondrion depending on which form is generated based on cytosolic pH. Highest expression levels of NFS1 are found in heart and skeletal muscle. Lower levels of expression are also found in liver, brain and pancreas. NFS1 is responsible for catalyzing the removal of sulfur from cysteine to form alanine, thereby supplying the inorganic sulfur for iron-sulfur (Fe-S) clusters. Fe-S clusters function as essential cofactors in a wide variety of events, including facilitation of electron transfer processes in oxidative phosphorylation, catalysis of enzymatic reactions in aconitase and dehydratases and maintenance of structural integrity in the DNA repair enzyme endonuclease III.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
NFS1 protein structure - BS8339 shown in red.