BS7289

antibody from Bioworld Technology, Inc
Targeting: CFB BF, BFD, H2-Bf
Provider product page for BS7289
Western blot
Immunohistochemistry

Antibody data

Product number
BS7289 - Provider product page
Provider
Bioworld Technology, Inc
Product name
CFB polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human CFB.
Description
This gene encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. This cluster includes several genes involved in regulation of the immune reaction. Polymorphisms in this gene are associated with a reduced risk of age-related macular degeneration. The polyadenylation site of this gene is 421 bp from the 5' end of the gene for complement component 2.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
CFB protein structure - BS7289 shown in red.