BS7798

antibody from Bioworld Technology, Inc

Targeting: TNFRSF13B CD267, IGAD2, TACI

Western blot (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

BS7798

Provider

Bioworld Technology, Inc

Product name

TNFRSF13B polyclonal antibody

Antibody type

Polyclonal

Antigen

Recombinant full length Human TNFRSF13B.

Description

The NFAT (nuclear factor of activated T cells) family of transcription factors regulates cytokine expression in T cells through cis-acting elements located in the promoters of the cytokine genes. The NFAT family consists of the cytoplasmic NFAT (NFATc), transcription factors NFATc1, NFATc2, NFATc3 and NFATc4, and nuclear NFAT (NFATn). Each of these transcription factors plays a role in T cell activation. CAML (calcium-signal modulating cyclophilin ligand) has been identified as an activator of NFAT and NF-IL2A when overexpressed in Jurkat cells. CAML has also been shown to activate calcineurin by causing calcium influx. TACI (transmembrane activator and CAML-interactor), a member of the TNF receptor superfamily, was identified based on its capacity to bind to CAML and has been shown to induce activation of NFAT in the presence of CAML.

Reactivity

Human

Host

Rabbit

Isotype

IgG

Vial size

100ul

Concentration

1 mg/ml

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.