AMM02378G

antibody from Leading Biology

Targeting: ACTA1 ACTA, NEM3

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

AMM02378G

Provider

Leading Biology

Product name

ACTA1 Antibody

Antibody type

Monoclonal

Description

The product encoded by this gene belongs to the actinfamily of proteins, which are highly conserved proteins that play arole in cell motility, structure and integrity. Alpha, beta andgamma actin isoforms have been identified, with alpha actins beinga major constituent of the contractile apparatus, while beta andgamma actins are involved in the regulation of cell motility. Thisactin is an alpha actin that is found in skeletal muscle. Mutationsin this gene cause nemaline myopathy type 3, congenital myopathywith excess of thin myofilaments, congenital myopathy with cores,and congenital myopathy with fiber-type disproportion, diseasesthat lead to muscle fiber defects.

Reactivity

Human

Host

Mouse

Isotype

IgG

Antibody clone number

337CT30.10.1

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.