DPABH-22110

antibody from Creative Diagnostics
Targeting: CD68 DKFZp686M18236, GP110, LAMP4, macrosialin, SCARD1
Provider product page for DPABH-22110
Western blot
ELISA
Immunocytochemistry
Immunoprecipitation
Immunohistochemistry
Flow cytometry

Antibody data

Product number
DPABH-22110 - Provider product page
Provider
Creative Diagnostics
Proper citation
Creative Diagnostics Cat#DPABH-22110, RRID:AB_2517570
Product name
Rabbit Anti-Human CD68 Polyclonal antibody
Antibody type
Polyclonal
Description
This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms.
Reactivity
Human, Mouse
Host
Rabbit
Conjugate
Unconjugated
Isotype
IgG
Vial size
50 uL
CD68 protein structure - DPABH-22110 shown in red.