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- Antibody Data
- Antigen structure
- References [16]
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- Western blot [1]
- Immunocytochemistry [1]
- Flow cytometry [3]
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- Product number
- ABIN152046 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Caveolin 1, Caveolae Protein, 22kDa (CAV1) antibody
- Antibody type
- Monoclonal
- Description
- Protein A purified
- Reactivity
- Human, Mouse, Rat, Sheep
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 7C8
- Vial size
- 0.1 mL
- Storage
- Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
- Handling
- Avoid freeze-thaw cycles
Submitted references Expression of Stromal Caveolin- 1 May Be a Predictor for Aggressive Behaviour of Breast Cancer.
The evaluation of the caveolin-1 and AT-rich interactive domain 1 alpha expressions in uterine smooth muscle tumors.
SMN affects membrane remodelling and anchoring of the protein synthesis machinery.
Increases in endothelial caveolin-1 and cavins correlate with cirrhosis progression.
ATP stimulates pannexin 1 internalization to endosomal compartments.
Phosphodiesterase 2A localized in the spinal cord contributes to inflammatory pain processing.
Enterohemorrhagic Escherichia coli hemolysin employs outer membrane vesicles to target mitochondria and cause endothelial and epithelial apoptosis.
Caveolin-1--a novel interacting partner of organic cation/carnitine transporter (Octn2): effect of protein kinase C on this interaction in rat astrocytes.
Effects of gravitational mechanical unloading in endothelial cells: association between caveolins, inflammation and adhesion molecules.
Characterization and identification of PARM-1 as a new potential oncogene.
AMP kinase activation improves angiogenesis in pulmonary artery endothelial cells with in utero pulmonary hypertension.
Matrix metalloproteinase-9 in homocysteine-induced intestinal microvascular endothelial paracellular and transcellular permeability.
Functional heterogeneity of breast fibroblasts is defined by a prostaglandin secretory phenotype that promotes expansion of cancer-stem like cells.
Quantitative proteomics of caveolin-1-regulated proteins: characterization of polymerase i and transcript release factor/CAVIN-1 IN endothelial cells.
Akt regulates L-type Ca2+ channel activity by modulating Cavalpha1 protein stability.
Immunopurification and characterization of rat adipocyte caveolae suggest their dissociation from insulin signaling.
Eliyatkin N, Aktas S, Diniz G, Ozgur HH, Ekin ZY, Kupelioglu A
Pathology oncology research : POR 2018 Jan;24(1):59-65
Pathology oncology research : POR 2018 Jan;24(1):59-65
The evaluation of the caveolin-1 and AT-rich interactive domain 1 alpha expressions in uterine smooth muscle tumors.
Ayaz D, Diniz G, Kahraman DS, Sayhan S, Uncel M, Karadeniz T, Sanci M
Indian journal of pathology & microbiology 2016 Jul-Sep;59(3):301-4
Indian journal of pathology & microbiology 2016 Jul-Sep;59(3):301-4
SMN affects membrane remodelling and anchoring of the protein synthesis machinery.
Gabanella F, Pisani C, Borreca A, Farioli-Vecchioli S, Ciotti MT, Ingegnere T, Onori A, Ammassari-Teule M, Corbi N, Canu N, Monaco L, Passananti C, Di Certo MG
Journal of cell science 2016 Feb 15;129(4):804-16
Journal of cell science 2016 Feb 15;129(4):804-16
Increases in endothelial caveolin-1 and cavins correlate with cirrhosis progression.
Yokomori H, Ando W, Yoshimura K, Yamazaki H, Takahashi Y, Oda M
Micron (Oxford, England : 1993) 2015 Sep;76:52-61
Micron (Oxford, England : 1993) 2015 Sep;76:52-61
ATP stimulates pannexin 1 internalization to endosomal compartments.
Boyce AK, Kim MS, Wicki-Stordeur LE, Swayne LA
The Biochemical journal 2015 Sep 15;470(3):319-30
The Biochemical journal 2015 Sep 15;470(3):319-30
Phosphodiesterase 2A localized in the spinal cord contributes to inflammatory pain processing.
Kallenborn-Gerhardt W, Lu R, Bothe A, Thomas D, Schlaudraff J, Lorenz JE, Lippold N, Real CI, Ferreirós N, Geisslinger G, Del Turco D, Schmidtko A
Anesthesiology 2014 Aug;121(2):372-82
Anesthesiology 2014 Aug;121(2):372-82
Enterohemorrhagic Escherichia coli hemolysin employs outer membrane vesicles to target mitochondria and cause endothelial and epithelial apoptosis.
Bielaszewska M, Rüter C, Kunsmann L, Greune L, Bauwens A, Zhang W, Kuczius T, Kim KS, Mellmann A, Schmidt MA, Karch H
PLoS pathogens 2013;9(12):e1003797
PLoS pathogens 2013;9(12):e1003797
Caveolin-1--a novel interacting partner of organic cation/carnitine transporter (Octn2): effect of protein kinase C on this interaction in rat astrocytes.
Czeredys M, Samluk Ł, Michalec K, Tułodziecka K, Skowronek K, Nałęcz KA
PloS one 2013;8(12):e82105
PloS one 2013;8(12):e82105
Effects of gravitational mechanical unloading in endothelial cells: association between caveolins, inflammation and adhesion molecules.
Grenon SM, Jeanne M, Aguado-Zuniga J, Conte MS, Hughes-Fulford M
Scientific reports 2013;3:1494
Scientific reports 2013;3:1494
Characterization and identification of PARM-1 as a new potential oncogene.
Charfi C, Levros LC Jr, Edouard E, Rassart E
Molecular cancer 2013 Jul 31;12:84
Molecular cancer 2013 Jul 31;12:84
AMP kinase activation improves angiogenesis in pulmonary artery endothelial cells with in utero pulmonary hypertension.
Teng RJ, Du J, Afolayan AJ, Eis A, Shi Y, Konduri GG
American journal of physiology. Lung cellular and molecular physiology 2013 Jan 1;304(1):L29-42
American journal of physiology. Lung cellular and molecular physiology 2013 Jan 1;304(1):L29-42
Matrix metalloproteinase-9 in homocysteine-induced intestinal microvascular endothelial paracellular and transcellular permeability.
Munjal C, Tyagi N, Lominadze D, Tyagi SC
Journal of cellular biochemistry 2012 Apr;113(4):1159-69
Journal of cellular biochemistry 2012 Apr;113(4):1159-69
Functional heterogeneity of breast fibroblasts is defined by a prostaglandin secretory phenotype that promotes expansion of cancer-stem like cells.
Rudnick JA, Arendt LM, Klebba I, Hinds JW, Iyer V, Gupta PB, Naber SP, Kuperwasser C
PloS one 2011;6(9):e24605
PloS one 2011;6(9):e24605
Quantitative proteomics of caveolin-1-regulated proteins: characterization of polymerase i and transcript release factor/CAVIN-1 IN endothelial cells.
Dávalos A, Fernández-Hernando C, Sowa G, Derakhshan B, Lin MI, Lee JY, Zhao H, Luo R, Colangelo C, Sessa WC
Molecular & cellular proteomics : MCP 2010 Oct;9(10):2109-24
Molecular & cellular proteomics : MCP 2010 Oct;9(10):2109-24
Akt regulates L-type Ca2+ channel activity by modulating Cavalpha1 protein stability.
Catalucci D, Zhang DH, DeSantiago J, Aimond F, Barbara G, Chemin J, Bonci D, Picht E, Rusconi F, Dalton ND, Peterson KL, Richard S, Bers DM, Brown JH, Condorelli G
The Journal of cell biology 2009 Mar 23;184(6):923-33
The Journal of cell biology 2009 Mar 23;184(6):923-33
Immunopurification and characterization of rat adipocyte caveolae suggest their dissociation from insulin signaling.
Souto RP, Vallega G, Wharton J, Vinten J, Tranum-Jensen J, Pilch PF
The Journal of biological chemistry 2003 May 16;278(20):18321-9
The Journal of biological chemistry 2003 May 16;278(20):18321-9
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IF image using ABIN152046 at 1:200 dilution (ON incubation) on EaHy926 endothelial cell line showing a clear localization in lipid raft/membrane (Photo courtesy of Alberto Davalos, Yale School of Medicine).
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- FACS
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- FACS
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- FACS
