BS6477

antibody from Bioworld Technology, Inc

Targeting: BAK1 BAK, BCL2L7, CDN1

Immunohistochemistry

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Validation data

Product number: BS6477 - Provider product page
Provider: Bioworld Technology, Inc
Product name: Bak polyclonal antibody
Antibody type: Polyclonal
Antigen: Recombinant full length Human Bak.
Description: Bak or Bcl2 homologous antagonist is a member of the Bcl2 family of proteins. The Bcl-2 related proteins interact with one another through the formation of homo and heterodimers. The susceptibility of cells to apoptotic stimuli is thought to be controlled by the relative ratios of the different Bcl2 family proteins. Bak has been demonstrated to accelerate the rate of apoptosis in growth factor deprived murine lymphoid, neuronal and fibroblastic cell lines. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Vial size: 100ul
Concentration: 1 mg/ml
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

BAK1 protein structure - BS6477 shown in red.