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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- PAB2439 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB2439, RRID:AB_1571638
- Product name
- BAK1 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of BAK1.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Nonredundant role of Bax and Bak in Bid-mediated apoptosis.
Association of Bax and Bak homo-oligomers in mitochondria. Bax requirement for Bak reorganization and cytochrome c release.
Bcl-2 family member Bfl-1/A1 sequesters truncated bid to inhibit is collaboration with pro-apoptotic Bak or Bax.
Cartron PF, Juin P, Oliver L, Martin S, Meflah K, Vallette FM
Molecular and cellular biology 2003 Jul;23(13):4701-12
Molecular and cellular biology 2003 Jul;23(13):4701-12
Association of Bax and Bak homo-oligomers in mitochondria. Bax requirement for Bak reorganization and cytochrome c release.
Mikhailov V, Mikhailova M, Degenhardt K, Venkatachalam MA, White E, Saikumar P
The Journal of biological chemistry 2003 Feb 14;278(7):5367-76
The Journal of biological chemistry 2003 Feb 14;278(7):5367-76
Bcl-2 family member Bfl-1/A1 sequesters truncated bid to inhibit is collaboration with pro-apoptotic Bak or Bax.
Werner AB, de Vries E, Tait SW, Bontjer I, Borst J
The Journal of biological chemistry 2002 Jun 21;277(25):22781-8
The Journal of biological chemistry 2002 Jun 21;277(25):22781-8
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- The BAK1 polyclonal antibody (Cat # PAB2439) is used in Western blot to detect BAK1 in A-375 cell lysate.
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with the BAK1 polyclonal antibody (Cat # PAB2439) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. HC = hepatocarcinoma.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
