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- Antibody Data
- Antigen structure
- References [671]
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- Western blot [1]
- Immunocytochemistry [1]
- Immunoprecipitation [1]
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- Product number
- 10745-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10745-1-AP, RRID:AB_2178878
- Product name
- NF-κB p65 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated NF-κB p65 antibody (Cat. #10745-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Renoprotective activity of Ribes diacanthum pall (RDP) against inflammation in cisplatin-stimulated mice model and human renal tubular epithelial cells.
Bombyx mori Akirin hijacks a viral peptide vSP27 encoded by BmCPV circRNA and activates the ROS-NF-κB pathway against viral infection.
Therapeutic effect of and mechanisms underlying the effect of miR-195-5p on subarachnoid hemorrhage-induced vasospasm and brain injury in rats.
An Inhibitor of NF-κB and an Agonist of AMPK: Network Prediction and Multi-Omics Integration to Derive Signaling Pathways for Acteoside Against Alzheimer's Disease.
Electroacupuncture Reduces Oocyte Number and Maintains Vascular Barrier Against Ovarian Hyperstimulation Syndrome by Regulating CD200.
Nuclear Factor Kappa-B/Homeobox A9-Mediated Modulation of Leucine-Rich Repeat Flightless-Interacting Protein 1 Is Involved in Advanced Glycation End Product-Induced Endothelial Dysfunction.
Chemerin promotes microangiopathy in diabetic retinopathy via activation of ChemR23 in rat primary microvascular endothelial cells.
Exploring the Oxidative Stress Mechanism of Buyang Huanwu Decoction in Intervention of Vascular Dementia Based on Systems Biology Strategy.
Yixintongmai Inhibits Proliferation and Migration and Promotes Apoptosis of Vascular Smooth Muscle Cells Cultured with High Glucose.
BMSCs Regulate Astrocytes through TSG-6 to Protect the Blood-Brain Barrier after Subarachnoid Hemorrhage.
Zanthoxylum bungeanum Seed Oil Attenuates LPS-Induced BEAS-2B Cell Activation and Inflammation by Inhibiting the TLR4/MyD88/NF-κB Signaling Pathway.
Downregulation of m6A Reader YTHDC2 Promotes the Proliferation and Migration of Malignant Lung Cells via CYLD/NF-κB Pathway.
Network Pharmacology Analysis of the Mechanisms of Compound Herba Sarcandrae (Fufang Zhongjiefeng) Aerosol in Chronic Pharyngitis Treatment.
The Spinal α7-Nicotinic Acetylcholine Receptor Contributes to the Maintenance of Cancer-Induced Bone Pain.
Bone Autophagy: A Potential Way of Exercise-Mediated Meg3/P62/Runx2 Pathway to Regulate Bone Formation in T2DM Mice.
BCI Suppresses RANKL-Mediated Osteoclastogenesis and Alleviates Ovariectomy-Induced Bone Loss.
Aspartate Metabolism Facilitates IL-1β Production in Inflammatory Macrophages.
Negative Regulation of RNF90 on RNA Virus-Triggered Antiviral Immune Responses Targeting MAVS.
Chlorogenic Acid Improves NAFLD by Regulating gut Microbiota and GLP-1.
Selonsertib Alleviates the Progression of Rat Osteoarthritis: An in vitro and in vivo Study.
Cronobacter sakazakii ATCC 29544 Translocated Human Brain Microvascular Endothelial Cells via Endocytosis, Apoptosis Induction, and Disruption of Tight Junction.
Effect of Protein O-Mannosyltransferase (MSMEG_5447) on M. smegmatis and Its Survival in Macrophages.
Astragalin Inhibits the Proliferation and Migration of Human Colon Cancer HCT116 Cells by Regulating the NF-κB Signaling Pathway.
Hepatitis B Surface Antigen Suppresses the Activation of Nuclear Factor Kappa B Pathway via Interaction With the TAK1-TAB2 Complex.
Experimental and clinical evidence suggests that GRPEL2 plays an oncogenic role in HCC development.
CALR-TLR4 Complex Inhibits Non-Small Cell Lung Cancer Progression by Regulating the Migration and Maturation of Dendritic Cells.
TPL Inhibits the Invasion and Migration of Drug-Resistant Ovarian Cancer by Targeting the PI3K/AKT/NF-κB-Signaling Pathway to Inhibit the Polarization of M2 TAMs.
SPNS2 Downregulation Induces EMT and Promotes Colorectal Cancer Metastasis via Activating AKT Signaling Pathway.
Yangonin modulates lipid homeostasis, ameliorates cholestasis and cellular senescence in alcoholic liver disease via activating nuclear receptor FXR.
Maresin-1 suppresses IL-1β-induced MMP-13 secretion by activating the PI3K/AKT pathway and inhibiting the NF-κB pathway in synovioblasts of an osteoarthritis rat model with treadmill exercise.
Salidroside alleviates liver inflammation in furan-induced mice by regulating oxidative stress and endoplasmic reticulum stress.
Tumor Necrosis Factor-stimulated Gene-6 (TSG-6) Secreted by BMSCs Regulates Activated Astrocytes by Inhibiting NF-κB Signaling Pathway to Ameliorate Blood Brain Barrier Damage After Intracerebral Hemorrhage.
Long noncoding RNA ANRIL knockdown attenuates neuroinflammation following ischemic stroke via suppressing the expression of NF-κB in vitro and in vivo.
Gastrodin protects against high glucose-induced cardiomyocyte toxicity via GSK-3β-mediated nuclear translocation of Nrf2.
Compound essential oils relieve oxidative stress caused by PM2 .5 exposure by inhibiting autophagy through the AMPK/mTOR pathway.
Synergy of nanodiamond-doxorubicin conjugates and PD-L1 blockade effectively turns tumor-associated macrophages against tumor cells.
Efficient Delivery of Chlorin e6 by Polyglycerol-Coated Iron Oxide Nanoparticles with Conjugated Doxorubicin for Enhanced Photodynamic Therapy of Melanoma.
Chondroprotective and antiarthritic effects of galangin in osteoarthritis: An in vitro and in vivo study.
Smilax china L. flavonoid alleviates HFHS-induced inflammation by regulating the gut-liver axis in mice.
MEST promotes lung cancer invasion and metastasis by interacting with VCP to activate NF-κB signaling.
Arsenic exposure induces intestinal barrier damage and consequent activation of gut-liver axis leading to inflammation and pyroptosis of liver in ducks.
TRIM38 protects chondrocytes from IL-1β-induced apoptosis and degeneration via negatively modulating nuclear factor (NF)-κB signaling.
Inhibition of TNFAIP1 ameliorates the oxidative stress and inflammatory injury in myocardial ischemia/reperfusion injury through modulation of Akt/GSK-3β/Nrf2 pathway.
Iguratimod decreases bleomycin-induced pulmonary fibrosis in association with inhibition of TNF-α in mice.
Helicobacter pylori infection disturbs the tumor immune microenvironment and is associated with a discrepant prognosis in gastric de novo diffuse large B-cell lymphoma.
Imbalanced inflammatory response in subchronic arsenic-induced liver injury and the protective effects of Ginkgo biloba extract in rats: Potential role of cytokines mediated cell-cell interactions.
Therapeutic potential of isobavachalcone, a natural flavonoid, in murine experimental colitis by inhibiting NF-κB p65.
Indispensable role of mitochondria in maintaining the therapeutic potential of curcumin in acute kidney injury.
Establishment of incontinence-associated dermatitis rat models and assessment of the therapeutic effects of zinc oxide, painless skin protective film and silicone dressing.
Myricetin ameliorates ox-LDL-induced HUVECs apoptosis and inflammation via lncRNA GAS5 upregulating the expression of miR-29a-3p.
Electroacupuncture restores intestinal mucosal barrier through TLR4/NF-κB p65 pathway in functional dyspepsia-like rats.
Berberine Inhibits MDA-MB-231 Cells as an Agonist of G Protein-Coupled Estrogen Receptor 1.
Cigarette smoking induces aberrant N6-methyladenosine of DAPK2 to promote non-small cell lung cancer progression by activating NF-κB pathway.
Downregulated fat mass and obesity-associated protein inhibits bone resorption and osteoclastogenesis by nuclear factor-kappa B inactivation.
FOXA2 inhibits doxorubicin-induced apoptosis via transcriptionally activating HBP rate-limiting enzyme GFPT1 in HCC cells.
Knockdown of ST6Gal-I expression in human hepatocellular carcinoma cells inhibits their exosome-mediated proliferation- and migration-promoting effects.
Protective effect of carvacrol on liver injury in type 2 diabetic db/db mice.
Overexpression of the nucleoporin Nup88 stimulates migration and invasion of HeLa cells.
Th17/IL-17 induces endothelial cell senescence via activation of NF-κB/p53/Rb signaling pathway.
Discovery of Phenolic Glycoside from Hyssopus cuspidatus Attenuates LPS-Induced Inflammatory Responses by Inhibition of iNOS and COX-2 Expression through Suppression of NF-κB Activation.
The histone deacetylase inhibitor belinostat ameliorates experimental autoimmune encephalomyelitis in mice by inhibiting TLR2/MyD88 and HDAC3/ NF-κB p65-mediated neuroinflammation.
HB-EGF-induced IL-8 secretion from airway epithelium leads to lung fibroblast proliferation and migration.
Allicin Ameliorates Intestinal Barrier Damage via Microbiota-Regulated Short-Chain Fatty Acids-TLR4/MyD88/NF-κB Cascade Response in Acrylamide-Induced Rats.
Mettl3 promotes oxLDL-mediated inflammation through activating STAT1 signaling.
Protection of CAPE-pNO2 Against Chronic Myocardial Ischemia by the TGF-Β1/Galectin-3 Pathway In Vivo and In Vitro.
Effects of ribosomal associated protein hnRNP D in gemcitabine-resistant pancreatic cancer.
Indole-3-Propionic Acid, a Functional Metabolite of Clostridium sporogenes, Promotes Muscle Tissue Development and Reduces Muscle Cell Inflammation.
Ripened Pu-Erh Tea Improved the Enterohepatic Circulation in a Circadian Rhythm Disorder Mice Model.
TRPV4-induced Müller cell gliosis and TNF-α elevation-mediated retinal ganglion cell apoptosis in glaucomatous rats via JAK2/STAT3/NF-κB pathway.
Intermittent hypoxia aggravates non-alcoholic fatty liver disease via RIPK3-dependent necroptosis-modulated Nrf2/NFκB signaling pathway.
Protective effect of the effective part of Andrographis paniculata (Burm.f.) Nees on PM2.5-induced lung injury in rats by modulating the NF-κB pathway.
Astaxanthin attenuated hyperuricemia and kidney inflammation by inhibiting uric acid synthesis and the NF-κ B/NLRP3 signaling pathways in potassium oxonate and hypoxanthine-induced hyperuricemia mice.
Protective effect of Apelin/APJ system on lipopolysaccharide-related cardiac dysfunction.
TUFM is involved in Alzheimer's disease-like pathologies that are associated with ROS.
Targeted regulation of lymphocytic ER stress response with an overall immunosuppression to alleviate allograft rejection.
Proof-of-concept study investigating the role of S100P-RAGE in nasopharyngeal carcinoma.
Mitochondrial TXN2 attenuates amyloidogenesis via selective inhibition of BACE1 expression.
Anti-angiogenesis and anti-metastasis effects of Polyphyllin VII on Hepatocellular carcinoma cells in vitro and in vivo.
Downregulation of CD151 restricts VCAM-1 mediated leukocyte infiltration to reduce neurobiological injuries after experimental stroke.
Anti-inflammatory activity of the water extract of Chloranthus serratus roots in LPS-stimulated RAW264.7 cells mediated by the Nrf2/HO-1, MAPK and NF-κB signaling pathways.
Glucagon-like peptide-1 (GLP-1) improved diabetic lung fibrosis via AMPK and microRNA-27a (miR-27a).
Macrophage regulator of G-protein signaling 12 contributes to inflammatory pain hypersensitivity.
Triptolide reduces salivary gland damage in a non-obese diabetic mice model of Sjögren's syndrome via JAK/STAT and NF-κB signaling pathways.
Hsa_circ_0056558 regulates cyclin-dependent kinase 6 by sponging microRNA-1290 to suppress the proliferation and differentiation in ankylosing spondylitis.
Cordyceps acid alleviates lung cancer in nude mice.
Crosstalk between adipocytes and M2 macrophages compensates for osteopenic phenotype in the Lrp5-deficient mice.
The miR-623/CXCL12 axis inhibits LPS-induced nucleus pulposus cell apoptosis and senescence.
Cardamonin protects nucleus pulposus cells against IL-1β-induced inflammation and catabolism via Nrf2/NF-κB axis.
Clostridium Butyricum ZJU-F1 Benefits the Intestinal Barrier Function and Immune Response Associated with Its Modulation of Gut Microbiota in Weaned Piglets.
The MIR155 host gene/microRNA-627/HMGB1/NF-κB loop modulates fibroblast proliferation and extracellular matrix deposition.
Effect of selenium-enriched kiwifruit on body fat reduction and liver protection in hyperlipidaemic mice.
A New Perspective on Ameliorating Depression-Like Behaviors: Suppressing Neuroinflammation by Upregulating PGC-1α.
Wogonin alleviates liver injury in sepsis through Nrf2-mediated NF-κB signalling suppression.
NF‑κB is negatively associated with Nurr1 to reduce the inflammatory response in Parkinson's disease.
Virus-inducible IGFALS facilitates innate immune responses by mediating IRAK1 and TRAF6 activation.
The N6-methyladenosine RNA-binding protein YTHDF1 modulates the translation of TRAF6 to mediate the intestinal immune response.
Dexmedetomidine post-conditioning attenuates cerebral ischemia following asphyxia cardiac arrest through down-regulation of apoptosis and neuroinflammation in rats.
Exosomal SNHG16 secreted by CSCs promotes glioma development via TLR7.
Identification of a Novel TAR RNA-Binding Protein 2 Modulator with Potential Therapeutic Activity against Hepatocellular Carcinoma.
Inducible ATP1B1 Upregulates Antiviral Innate Immune Responses by the Ubiquitination of TRAF3 and TRAF6.
IFI16 directly senses viral RNA and enhances RIG-I transcription and activation to restrict influenza virus infection.
miR-671-5p Attenuates Neuroinflammation via Suppressing NF-κB Expression in an Acute Ischemic Stroke Model.
Effects of medicine food Fructus Gardeniae on liver and kidney functions after oral administration to rats for 12 weeks.
N-acetylserotonin alleviated the expression of interleukin-1β in retinal ischemia-reperfusion rats via the TLR4/NF-κB/NLRP3 pathway.
GLP-1R activation ameliorated novel-object recognition memory dysfunction via regulating hippocampal AMPK/NF-κB pathway in neuropathic pain mice.
Evolutionary history and functional characterization of Lj-TICAM-a and Lj-TICAM-b formed via lineage-specific tandem duplication in lamprey (Lampetra japonica).
Diterpenoids from the seeds of Euphorbia lathyris and their anti-inflammatory activity.
Baicalein Delays H2O2-Induced Astrocytic Senescence through Inhibition of Senescence-Associated Secretory Phenotype (SASP), Suppression of JAK2/STAT1/NF-κB Pathway, and Regulation of Leucine Metabolism.
Adjuvant treatment and molecular mechanism of probiotic compounds in patients with gastric cancer after gastrectomy.
Role of IL-6-IL-27 Complex in Host Antiviral Immune Response.
Physcion 8-O-β-glucopyranoside ameliorates liver fibrosis through inflammation inhibition by regulating SIRT3-mediated NF-κB P65 nuclear expression.
Limonin ameliorates dextran sulfate sodium-induced chronic colitis in mice by inhibiting PERK-ATF4-CHOP pathway of ER stress and NF-κB signaling.
Amygdalin inhibits TGFβ1-induced activation of hepatic stellate cells (HSCs) in vitro and CCl4-induced hepatic fibrosis in rats in vivo.
Hyperoside ameliorates the progression of osteoarthritis: An in vitro and in vivo study.
Dexmedetomidine exerts cardioprotective effect through miR-146a-3p targeting IRAK1 and TRAF6 via inhibition of the NF-κB pathway.
miR-34a-5p up-regulates the IL-1β/COX2/PGE2 inflammation pathway and induces the release of CGRP via inhibition of SIRT1 in rat trigeminal ganglion neurons.
Antioxidant and Immunomodulatory Properties of Partially purified Exopolysaccharide from Lactobacillus Casei Isolated from Chinese Northeast Sauerkraut.
Diosmetin Ameliorates Nonalcoholic Steatohepatitis through Modulating Lipogenesis and Inflammatory Response in a STAT1/CXCL10-Dependent Manner.
MicroRNA-150 affects endoplasmic reticulum stress via MALAT1-miR-150 axis-mediated NF-κB pathway in LPS-challenged HUVECs and septic mice.
MicroRNA-520c-3p suppresses vascular endothelium dysfunction by targeting RELA and regulating the AKT and NF-κB signaling pathways.
Inhibitory activity of narirutin on RBL-2H3 cells degranulation.
Paeonol ameliorates CFA-induced inflammatory pain by inhibiting HMGB1/TLR4/NF-κB p65 pathway.
Downregulating lncRNA PRNCR1 ameliorates LPS-induced pulmonary vascular endothelial cell injury by modulating miR-330-5p/TLR4 axis.
Inflammatory signals induce MUC16 expression in ovarian cancer cells via NF-κB activation.
Exercise reduces hyperlipidemia-induced kidney damage in apolipoprotein E-deficient mice.
Identification of thrombomodulin as a dynamic monitoring biomarker for deep venous thrombosis evolution.
Poly(ADP-ribose) polymerase-1 inhibitor ameliorates dextran sulfate sodium-induced colitis in mice by regulating the balance of Th17/Treg cells and inhibiting the NF-κB signaling pathway.
m6A mRNA methylation regulates testosterone synthesis through modulating autophagy in Leydig cells.
MSCs-extracellular vesicles attenuated neuroinflammation, synapse damage and microglial phagocytosis after hypoxia-ischemia injury by preventing osteopontin expression.
Escalating dose-multiple binge methamphetamine treatment elicits neurotoxicity, altering gut microbiota and fecal metabolites in mice.
Ripened Pu-erh Tea Extract Promotes Gut Microbiota Resilience against Dextran Sulfate Sodium Induced Colitis.
Hypothermic oxygenated perfusion inhibits HECTD3-mediated TRAF3 polyubiquitination to alleviate DCD liver ischemia-reperfusion injury.
HUCMSCs transplantation combined with ultrashort wave therapy attenuates neuroinflammation in spinal cord injury through NUR77/ NF-κB pathway.
Icariin ameliorates streptozocin-induced diabetic nephropathy through suppressing the TLR4/NF-κB signal pathway.
Protection Mechanisms Underlying Oral Administration of Chlorogenic Acid against Cadmium-Induced Hepatorenal Injury Related to Regulating Intestinal Flora Balance.
C-X3-C motif chemokine ligand 1/receptor 1 regulates the M1 polarization and chemotaxis of macrophages after hypoxia/reoxygenation injury.
Simiao Qingwen Baidu decoction inhibits Epstein-Barr virus-induced B lymphoproliferative disease and lytic viral replication.
Bergenin alleviates H2 O2 -induced oxidative stress and apoptosis in nucleus pulposus cells: Involvement of the PPAR-γ/NF-κB pathway.
Amelioratory effect of neoandrographolide on myocardial ischemic-reperfusion injury by its anti-inflammatory and anti-apoptotic activities.
Morinda officinalis oligosaccharides alleviate depressive-like behaviors in post-stroke rats via suppressing NLRP3 inflammasome to inhibit hippocampal inflammation.
Expression and role of interleukin-1β and associated biomarkers in deep vein thrombosis.
Diterpenoid alkaloids from Delphinium forrestii var. viride and their anti-inflammation activity.
Enriched environment mitigates depressive behavior by changing the inflammatory activation phenotype of microglia in the hippocampus of depression model rats.
Acetylcholinesterase inhibition with Pyridostigmine attenuates hypertension and neuroinflammation in the paraventricular nucleus in rat model for Preeclampsia.
ILC2s induce adaptive Th2-type immunity in different stages of tuberculosis through the Notch-GATA3 pathway.
Bixin protects mice against bronchial asthma though modulating PI3K/Akt pathway.
Senescence marker protein 30 (SMP30) protects against high glucose-induced apoptosis, oxidative stress and inflammatory response in retinal ganglion cells by enhancing Nrf2 activation via regulation of Akt/GSK-3β pathway.
Sub-chronic exposure to realgar induces liver injury via upregulating the TXNIP/NLRP3 pathway and disturbing bile acid homeostasis in mice.
Protective effect of combination of anakinra and MCC950 against acute lung injury is achieved through suppression of the NF-κB-mediated-MAPK and NLRP3-caspase pathways.
Guanosine and uridine alleviate airway inflammation via inhibition of the MAPK and NF-κB signals in OVA-induced asthmatic mice.
Inhibitor of apoptosis-stimulating p53 protein protects against inflammatory bowel disease in mice models by inhibiting the nuclear factor kappa B signaling.
CDDO-Im exerts antidepressant-like effects via the Nrf2/ARE pathway in a rat model of post-stroke depression.
Yak milk-derived exosomes alleviate lipopolysaccharide-induced intestinal inflammation by inhibiting PI3K/AKT/C3 pathway activation.
Celastrol exerts a neuroprotective effect by directly binding to HMGB1 protein in cerebral ischemia-reperfusion.
Ginsenoside Rg5 Improves Insulin Resistance and Mitochondrial Biogenesis of Liver via Regulation of the Sirt1/PGC-1α Signaling Pathway in db/db Mice.
Aiduqing formula inhibits breast cancer metastasis by suppressing TAM/CXCL1-induced Treg differentiation and infiltration.
Acute ischemic stroke triggers a cellular senescence-associated secretory phenotype.
Heteronemin Suppresses Lymphangiogenesis through ARF-1 and MMP-9/VE-Cadherin/Vimentin.
Glycyrrhizic Acid Alleviates Lipopolysaccharide (LPS)-Induced Acute Lung Injury by Regulating Angiotensin-Converting Enzyme-2 (ACE2) and Caveolin-1 Signaling Pathway.
Tubeimoside I protects against sepsis-induced cardiac dysfunction via SIRT3.
The epigenetic regulator BRD4 is involved in cadmium-triggered inflammatory response in rat kidney.
Fab Fragment of Immunoglobulin Y Modulates NF-κB and MAPK Signaling through TLR4 and αVβ3 Integrin and Inhibits the Inflammatory Effect on R264.7 Macrophages.
Isoorientin Attenuated the Pyroptotic Hepatocyte Damage Induced by Benzo[a]pyrene via ROS/NF-κB/NLRP3/Caspase-1 Signaling Pathway.
Ophiocordyceps lanpingensis polysaccharides alleviate chronic kidney disease through MAPK/NF-κB pathway.
Wharton's Jelly Mesenchymal Stem Cell-Derived Extracellular Vesicles Reduce SARS-CoV2-Induced Inflammatory Cytokines Under High Glucose and Uremic Toxin Conditions.
METTL3 involves the progression of osteoarthritis probably by affecting ECM degradation and regulating the inflammatory response.
Anti-thrombotic activity of phenolic acids obtained from Salvia miltiorrhiza f. alba in TNF-α-stimulated endothelial cells via the NF-κB/JNK/p38 MAPK signaling pathway.
African Swine Fever Virus MGF360-12L Inhibits Type I Interferon Production by Blocking the Interaction of Importin α and NF-κB Signaling Pathway.
Small molecule screening identified cepharanthine as an inhibitor of porcine reproductive and respiratory syndrome virus infection in vitro by suppressing integrins/ILK/RACK1/PKCα/NF-κB signalling axis.
Curcumin inhibits the growth of liver cancer by impairing myeloid-derived suppressor cells in murine tumor tissues.
Ginsenoside Rh4 alleviates antibiotic-induced intestinal inflammation by regulating the TLR4-MyD88-MAPK pathway and gut microbiota composition.
Hydrogen Sulfide Attenuates Aortic Remodeling in Aortic Dissection Associating with Moderated Inflammation and Oxidative Stress through a NO-Dependent Pathway.
Deficiency of CD147 Attenuated Non-alcoholic Steatohepatitis Progression in an NLRP3-Dependent Manner.
Blockade of Macrophage CD147 Protects Against Foam Cell Formation in Atherosclerosis.
Chronic intermittent hypoxia vs chronic continuous hypoxia: Effects on vascular endothelial function and myocardial contractility.
Bta-miR-223 Targeting CBLB Contributes to Resistance to Staphylococcus aureus Mastitis Through the PI3K/AKT/NF-κB Pathway.
Koumine Alleviates Lipopolysaccharide-Induced Intestinal Barrier Dysfunction in IPEC-J2 Cells by Regulating Nrf2/NF-κ
Effects of intragastric administration of La2O3 nanoparticles on mouse testes.
GNAS promotes inflammation-related hepatocellular carcinoma progression by promoting STAT3 activation.
Dietary Baicalin Zinc Supplementation Alleviates Oxidative Stress and Enhances Nutrition Absorption in Deoxynivalenol Challenged Pigs.
Alpha-Fetoprotein Regulates the Expression of Immune-Related Proteins through the NF-κB (P65) Pathway in Hepatocellular Carcinoma Cells.
Neuroprotective Effects of the Sonic Hedgehog Signaling Pathway in Ischemic Injury through Promotion of Synaptic and Neuronal Health.
Aloe Emodin Reduces Cardiac Inflammation Induced by a High-Fat Diet through the TLR4 Signaling Pathway.
The Evaluation of the Antioxidant and Intestinal Protective Effects of Baicalin-Copper in Deoxynivalenol-Challenged Piglets.
The Class III PI3K/Beclin-1 Autophagic Pathway Participates in the mmLDL-Induced Upregulation of ETA Receptor in Mouse Mesenteric Arteries.
Thymoquinone Protects against Hyperlipidemia-Induced Cardiac Damage in Low-Density Lipoprotein Receptor-Deficient (LDL-R-/-) Mice via Its Anti-inflammatory and Antipyroptotic Effects.
The Herbal Medicine Scutellaria-Coptis Alleviates Intestinal Mucosal Barrier Damage in Diabetic Rats by Inhibiting Inflammation and Modulating the Gut Microbiota.
Protective Effects of Cinnamaldehyde against Mesenteric Ischemia-Reperfusion-Induced Lung and Liver Injuries in Rats.
Anti-Inflammatory and Antioxidant Effect of Eucommia ulmoides Polysaccharide in Hepatic Ischemia-Reperfusion Injury by Regulating ROS and the TLR-4-NF-κB Pathway.
Effect of Thymoquinone on Acute Kidney Injury Induced by Sepsis in BALB/c Mice.
PRMT6 mediates inflammation via activation of the NF-κB/p65 pathway on a cigarette smoke extract-induced murine emphysema model.
Ozone Therapy Attenuates NF-κB-Mediated Local Inflammatory Response and Activation of Th17 Cells in Treatment for Psoriasis.
Sevoflurane-Induced Neuroapoptosis in Rat Dentate Gyrus Is Activated by Autophagy Through NF-κB Signaling on the Late-Stage Progenitor Granule Cells.
Emodin Protects Against Acute Pancreatitis-Associated Lung Injury by Inhibiting NLPR3 Inflammasome Activation via Nrf2/HO-1 Signaling.
Salvianolic Acid B Improves Chronic Mild Stress-Induced Depressive Behaviors in Rats: Involvement of AMPK/SIRT1 Signaling Pathway.
β-catenin regulates myocardial ischemia/reperfusion injury following heterotopic heart transplantation in mice by modulating PTEN pathways.
The LINC00365/SCGB2A1 (Mammaglobin B) Axis Down-Regulates NF-κB Signaling and Is Associated with the Progression of Gastric Cancer.
Dl-3-n-Butylphthalide Promotes Remyelination and Suppresses Inflammation by Regulating AMPK/SIRT1 and STAT3/NF-κB Signaling in Chronic Cerebral Hypoperfusion.
Resatorvid Relieves Breast Cancer Complicated with Depression by Inactivating Hippocampal Microglia Through TLR4/NF-κB/NLRP3 Signaling Pathway.
Hyperoside Protects Human Umbilical Vein Endothelial Cells Against Anticardiolipin Antibody-Induced Injury by Activating Autophagy.
Inhibitory Effects of the Lactobacillus rhamnosus GG Effector Protein HM0539 on Inflammatory Response Through the TLR4/MyD88/NF-кB Axis.
Herpes Simplex Virus 1 UL2 Inhibits the TNF-α-Mediated NF-κB Activity by Interacting With p65/p50.
Aucubin Attenuates Liver Ischemia-Reperfusion Injury by Inhibiting the HMGB1/TLR-4/NF-κB Signaling Pathway, Oxidative Stress, and Apoptosis.
Sodium Butyrate Abrogates the Growth and Pathogenesis of Mycobacterium bovis via Regulation of Cathelicidin (LL37) Expression and NF-κB Signaling.
Mycoplasma genitalium Protein of Adhesion Induces Inflammatory Cytokines via Cyclophilin A-CD147 Activating the ERK-NF-κB Pathway in Human Urothelial Cells.
Serine Supports IL-1β Production in Macrophages Through mTOR Signaling.
Selenomethionine Suppressed TLR4/NF-κB Pathway by Activating Selenoprotein S to Alleviate ESBL Escherichia coli-Induced Inflammation in Bovine Mammary Epithelial Cells and Macrophages.
Sevoflurane Protects against Intestinal Ischemia-Reperfusion Injury by Activating Peroxisome Proliferator-Activated Receptor Gamma/Nuclear Factor-κB Pathway in Rats.
GFPT2 promotes metastasis and forms a positive feedback loop with p65 in colorectal cancer.
Genetic and pharmacological activation of Hedgehog signaling inhibits osteoclastogenesis and attenuates titanium particle-induced osteolysis partly through suppressing the JNK/c-Fos-NFATc1 cascade.
Dynorphin activation of kappa opioid receptor promotes microglial polarization toward M2 phenotype via TLR4/NF-κB pathway.
Geraniol-mediated osteoarthritis improvement by down-regulating PI3K/Akt/NF-κB and MAPK signals: In vivo and in vitro studies.
CEACAM1 Inhibited IκB-α/NF-κB Signal Pathway Via Targeting MMP-9/TIMP-1 Axis in Diabetic Atherosclerosis.
Cetuximab enhances oridonin-induced apoptosis through mitochondrial pathway and endoplasmic reticulum stress in laryngeal squamous cell carcinoma cells.
Cinnamaldehyde protects against rat intestinal ischemia/reperfusion injuries by synergistic inhibition of NF-κB and p53.
The effect of monotropein on alleviating cisplatin-induced acute kidney injury by inhibiting oxidative damage, inflammation and apoptosis.
Staphylococcal enterotoxin M induced inflammation and impairment of bovine mammary epithelial cells.
Monotropein alleviates secondary liver injury in chronic colitis by regulating TLR4/NF-κB signaling and NLRP3 inflammasome.
Copper induces oxidative stress with triggered NF-κB pathway leading to inflammatory responses in immune organs of chicken.
LncRNA AY343892 inhibits breast cancer development by positively regulating BRCA1-mediated transcription of PTEN.
TLR4 contributes to the damage of cartilage and subchondral bone in discectomy-induced TMJOA mice.
Potential hazardous effects of printing room PM2.5 exposure include promotion of lung inflammation and subsequent injury.
(-)-Hydroxycitric Acid Alleviates Oleic Acid-Induced Steatosis, Oxidative Stress, and Inflammation in Primary Chicken Hepatocytes by Regulating AMP-Activated Protein Kinase-Mediated Reactive Oxygen Species Levels.
Ketogenic Diet Elicits Antitumor Properties through Inducing Oxidative Stress, Inhibiting MMP-9 Expression, and Rebalancing M1/M2 Tumor-Associated Macrophage Phenotype in a Mouse Model of Colon Cancer.
CP-25 improves nephropathy in collagen-induced arthritis rats by inhibiting the renal inflammatory response.
microRNA-421-3p prevents inflammatory response in cerebral ischemia/reperfusion injury through targeting m6A Reader YTHDF1 to inhibit p65 mRNA translation.
PDLIM2 protects articular chondrocytes from lipopolysaccharide-induced apoptosis, degeneration and inflammatory injury through down-regulation of nuclear factor (NF)-κB signaling.
Panax notoginseng saponin R1 modulates TNF-α/NF-κB signaling and attenuates allergic airway inflammation in asthma.
Proteases Activate Pregnancy Neutrophils by a Protease-Activated Receptor 1 Pathway: Epigenetic Implications for Preeclampsia.
Role of TLR4/MyD88/NF-κB signaling in the contrast-induced injury of renal tubular epithelial cells.
Protective effect of astaxanthin against SnS2 nanoflowers induced testes toxicity by suppressing RIPK1-RIPK3-MLKL signaling in mice.
The anti-inflammatory potential of protein-bound anthocyanin compounds from purple sweet potato in LPS-induced RAW264.7 macrophages.
Crocin ameliorates arsenic trioxide‑induced cardiotoxicity via Keap1-Nrf2/HO-1 pathway: Reducing oxidative stress, inflammation, and apoptosis.
Acetylharpagide Protects Mice from Staphylococcus Aureus-Induced Acute Lung Injury by Inhibiting NF-κB Signaling Pathway.
Inhibition of notch enhances the anti-atherosclerotic effects of LXR agonists while reducing fatty liver development in ApoE-deficient mice.
ADAM12 silencing promotes cellular apoptosis by activating autophagy in choriocarcinoma cells.
Pin1 promotes pancreatic cancer progression and metastasis by activation of NF-κB-IL-18 feedback loop.
Annexin-1 Mimetic Peptide Ac2-26 Suppresses Inflammatory Mediators in LPS-Induced Astrocytes and Ameliorates Pain Hypersensitivity in a Rat Model of Inflammatory Pain.
Porcine parvovirus nonstructural protein NS1 activates NF-κB and it involves TLR2 signaling pathway.
Protective effect of ginsenoside Rg5 against kidney injury via inhibition of NLRP3 inflammasome activation and the MAPK signaling pathway in high-fat diet/streptozotocin-induced diabetic mice.
Ruscogenin alleviates LPS-induced pulmonary endothelial cell apoptosis by suppressing TLR4 signaling.
Hic-5 deficiency attenuates hepatic ischemia reperfusion injury through TLR4/NF-κB signaling pathways.
Time serial transcriptome reveals Cyp2c29 as a key gene in hepatocellular carcinoma development.
Inhibition of the NLRP3-inflammasome prevents cognitive deficits in experimental autoimmune encephalomyelitis mice via the alteration of astrocyte phenotype.
Androgen aggravates liver fibrosis by activation of NLRP3 inflammasome in CCl4-induced liver injury mouse model.
Ketamine attenuates high-glucose-mediated endothelial inflammation in human umbilical vein endothelial cells.
Pyrroloquinoline quinone attenuates isoproterenol hydrochloride‑induced cardiac hypertrophy in AC16 cells by inhibiting the NF‑κB signaling pathway.
Treatment with a probiotic combination reduces abdominal adhesion in rats by decreasing intestinal inflammation and restoring microbial composition.
Influence of feature rankers in the construction of molecular activity prediction models.
Oxymatrine suppresses IL-1β-induced degradation of the nucleus pulposus cell and extracellular matrix through the TLR4/NF-κB signaling pathway.
Ubiquitination of P53 by E3 ligase MKRN2 promotes melanoma cell proliferation.
The Immunomodulatory Effects and Mechanisms of Tim-3 Action in the Early Stage of Mice with Severe Acute Pancreatitis.
RNF90 negatively regulates cellular antiviral responses by targeting MITA for degradation.
IFI16 promotes cervical cancer progression by upregulating PD-L1 in immunomicroenvironment through STING-TBK1-NF-kB pathway.
Far-infrared radiation prevents decline in β-cell mass and function in diabetic mice via the mitochondria-mediated Sirtuin1 pathway.
Wnt5a-induced M2 polarization of tumor-associated macrophages via IL-10 promotes colorectal cancer progression.
Dendrobium officinale polysaccharides protected against ethanol-induced acute liver injury in vivo and in vitro via the TLR4/NF-κB signaling pathway.
The protective effect of hesperetin in osteoarthritis: an in vitro and in vivo study.
Monocyte-derived extracellular vesicles upon treated by palmitate promote endothelial migration and monocytes attachment to endothelial cells.
Suppression of high-mobility group box 1 ameliorates xerostomia in a Sjögren syndrome-triggered mouse model.
Tle1 attenuates hepatic ischemia/reperfusion injury by suppressing NOD2/NF-κB signaling.
Jmjd3 is involved in the susceptibility to depression induced by maternal separation via enhancing the neuroinflammation in the prefrontal cortex and hippocampus of male rats.
Integrin β3, a RACK1 interacting protein, is critical for porcine reproductive and respiratory syndrome virus infection and NF-κB activation in Marc-145 cells.
Evaluation of the post-treatment anti-inflammatory capacity of osteoarthritic chondrocytes: An in vitro study using baicalein.
Tubeimoside I improves survival of mice in sepsis by inhibiting inducible nitric oxide synthase expression.
Tannic acid ameliorates arsenic trioxide-induced nephrotoxicity, contribution of NF-κB and Nrf2 pathways.
MGP Promotes Colon Cancer Proliferation by Activating the NF-κB Pathway through Upregulation of the Calcium Signaling Pathway.
Endosulfan induces endothelial inflammation and dysfunction via IRE1α/NF-κB signaling pathway.
Porcine RACK1 negatively regulates the infection of classical swine fever virus and the NF-κB activation in PK-15 cells.
Maternal Exposure to Di-n-butyl Phthalate Promotes the Formation of Testicular Tight Junctions through Downregulation of NF-κB/COX-2/PGE2/MMP-2 in Mouse Offspring.
The gut microbial metabolite trimethylamine N-oxide aggravates GVHD by inducing M1 macrophage polarization in mice.
Normothermic Machine Perfusion Combined with Bone Marrow Mesenchymal Stem Cells Improves the Oxidative Stress Response and Mitochondrial Function in Rat Donation After Circulatory Death Livers.
Karyopherin α 2 promotes proliferation, migration and invasion through activating NF-κB/p65 signaling pathways in melanoma cells.
Retinoic acid attenuates cardiac injury induced by hyperglycemia in pre- and post-delivery mice.
Plumbagin attenuated oxygen-glucose deprivation/reoxygenation-induced injury in human SH-SY5Y cells by inhibiting NOX4-derived ROS-activated NLRP3 inflammasome.
The m6A methyltransferase METTL3 cooperates with demethylase ALKBH5 to regulate osteogenic differentiation through NF-κB signaling.
Crocin attenuates isoprenaline-induced myocardial fibrosis by targeting TLR4/NF-κB signaling: connecting oxidative stress, inflammation, and apoptosis.
MiR-22 restrains proliferation of rheumatoid arthritis by targeting IL6R and may be concerned with the suppression of NF-κB pathway.
Protease Amplification of the Inflammatory Response Induced by Commensal Bacteria: Implications for Racial Disparity in Term and Preterm Birth.
MiR-146a down-regulates inflammatory response by targeting TLR3 and TRAF6 in Coxsackievirus B infection.
Hic-5 deficiency protects cerulein-induced chronic pancreatitis via down-regulation of the NF-κB (p65)/IL-6 signalling pathway.
Antidepressant activity of ω-3 polyunsaturated fatty acids in ovariectomized rats: role of neuroinflammation and microglial polarization.
Dopamine attenuates lipopolysaccharide-induced expression of proinflammatory cytokines by inhibiting the nuclear translocation of NF-κB p65 through the formation of dopamine quinone in microglia.
The Interleukin-33/ST2 axis promotes glioma mesenchymal transition, stemness and TMZ resistance via JNK activation.
Ginsenoside Rk1 induces apoptosis and downregulates the expression of PD-L1 by targeting the NF-κB pathway in lung adenocarcinoma.
The potential of Diosgenin in treating psoriasis: Studies from HaCaT keratinocytes and imiquimod-induced murine model.
Dietary pterostilbene supplementation attenuates intestinal damage and immunological stress of broiler chickens challenged with lipopolysaccharide.
Neuroinflammation induced by secretion of acetylated HMGB1 from activated microglia in hippocampi of mice following chronic cold exposure.
Baicalein attenuates the neuroinflammation in LPS-activated BV-2 microglial cells through suppression of pro-inflammatory cytokines, COX2/NF-κB expressions and regulation of metabolic abnormality.
Lactobacillus johnsonii L531 ameliorates enteritis via elimination of damaged mitochondria and suppression of SQSTM1-dependent mitophagy in a Salmonella infantis model of piglet diarrhea.
Polyphyllin VII induces apoptotic cell death via inhibition of the PI3K/Akt and NF‑κB pathways in A549 human lung cancer cells.
Network pharmacology based research into the effect and mechanism of Xijiao Dihuang decoction against sepsis.
N-WASP knockdown upregulates inflammatory cytokines expression in human gingival fibroblasts.
Silencing of PTX3 alleviates LPS-induced inflammatory pain by regulating TLR4/NF-κB signaling pathway in mice.
GDF15 induced by compressive force contributes to osteoclast differentiation in human periodontal ligament cells.
GABA-mediated activated microglia induce neuroinflammation in the hippocampus of mice following cold exposure through the NLRP3 inflammasome and NF-κB signaling pathways.
Protective effect of hydroxysafflor yellow A on dopaminergic neurons against 6-hydroxydopamine, activating anti-apoptotic and anti-neuroinflammatory pathways.
Hepatoprotective effects of Camellia nitidissima aqueous ethanol extract against CCl4-induced acute liver injury in SD rats related to Nrf2 and NF-κB signalling.
Pre-ischemic renal lavage protects against renal ischemia-reperfusion injury by attenuation of local and systemic inflammatory responses.
Ameliorative effects and mechanism of crocetin in arsenic trioxide‑induced cardiotoxicity in rats.
Mechanisms underlying the protective effect of tannic acid against arsenic trioxide‑induced cardiotoxicity in rats: Potential involvement of mitochondrial apoptosis.
Hepatitis B virus core protein promotes the expression of neuraminidase 1 to facilitate hepatocarcinogenesis.
Fat Encapsulation Reduces Diarrhea in Piglets Partially by Repairing the Intestinal Barrier and Improving Fatty Acid Transport.
Multi-walled carbon nanotubes decrease neuronal NO synthase in 3D brain organoids.
Chronic ethanol exposure induces neuroinflammation in H4 cells through TLR3 / NF-κB pathway and anxiety-like behavior in male C57BL/6 mice.
Akebia Saponin D suppresses inflammation in chondrocytes via the NRF2/HO-1/NF-κB axis and ameliorates osteoarthritis in mice.
Saturated fatty acids activate the inflammatory signalling pathway in Schwann cells: Implication in sciatic nerve injury.
Glycitin Suppresses Cartilage Destruction of Osteoarthritis in Mice.
Neferine Inhibits Expression of Inflammatory Mediators and Matrix Degrading Enzymes in IL-1β-Treated Rat Chondrocytes via Suppressing MAPK and NF-κB Signaling Pathways.
Schisandrin B improves cerebral ischemia and reduces reperfusion injury in rats through TLR4/NF-κB signaling pathway inhibition.
Regorafenib suppresses epidermal growth factor receptor signaling-modulated progression of colorectal cancer.
Anti-inflammatory effect of Ganluyin, a Chinese classic prescription, in chronic pharyngitis rat model.
Antidepressant-like Effect of Merazin Hydrate Depends on NO/ERK by Suppressing Its Downstream NF-κB or Nonactivating CREB/BDNF in Mouse Hippocampus.
Protective function of exosomes from adipose tissue-derived mesenchymal stem cells in acute kidney injury through SIRT1 pathway.
The response of phenoloxidase to cadmium-disturbed hepatopancreatic immune-related molecules in freshwater crayfish Procambarus clarkii.
Therapeutic effects of recombinant human brain natriuretic peptide on sepsis-associated encephalopathy in mice.
Berberine combined with cyclosporine A alleviates acute graft-versus-host disease in murine models.
p-Coumaric Acid Attenuates IL-1β-Induced Inflammatory Responses and Cellular Senescence in Rat Chondrocytes.
HMGB1 Mediates Paraquat-Induced Neuroinflammatory Responses via Activating RAGE Signaling Pathway.
Icariside II attenuates eosinophils-induced airway inflammation and remodeling via inactivation of NF-κB and STAT3 in an asthma mouse model.
A Combination of Formic Acid and Monolaurin Attenuates Enterotoxigenic Escherichia coli Induced Intestinal Inflammation in Piglets by Inhibiting the NF-κB/MAPK Pathways with Modulation of Gut Microbiota.
Anti-neuroinflammatory effects of dimethylaminomylide (DMAMCL, i.e., ACT001) are associated with attenuating the NLRP3 inflammasome in MPTP-induced Parkinson disease in mice.
Hot-water extract of ripened Pu-erh tea attenuates DSS-induced colitis through modulation of the NF-κB and HIF-1α signaling pathways in mice.
Liquiritin, a novel inhibitor of TRPV1 and TRPA1, protects against LPS-induced acute lung injury.
Wu-Mei-Wan ameliorates chronic colitis-associated intestinal fibrosis through inhibiting fibroblast activation.
Interleukin-17 suppresses grass carp reovirus infection in Ctenopharyngodon idellus kidney cells by activating NF-κB signaling.
Silica particles disorganize the polarization of pulmonary macrophages in mice.
NUDT21 inhibits bladder cancer progression through ANXA2 and LIMK2 by alternative polyadenylation.
Copy number gain of ZEB1 mediates a double-negative feedback loop with miR-33a-5p that regulates EMT and bone metastasis of prostate cancer dependent on TGF-β signaling.
Nanozyme-mediated catalytic nanotherapy for inflammatory bowel disease.
Scorpion Venom Analgesic Peptide, BmK AGAP Inhibits Stemness, and Epithelial-Mesenchymal Transition by Down-Regulating PTX3 in Breast Cancer.
Decreased miR-218-5p Levels as a Serum Biomarker in Bone Metastasis of Prostate Cancer.
MicroRNA-145 Protects against Myocardial Ischemia Reperfusion Injury via CaMKII-Mediated Antiapoptotic and Anti-Inflammatory Pathways.
Protective Effect of Methane-Rich Saline on Acetic Acid-Induced Ulcerative Colitis via Blocking the TLR4/NF-κB/MAPK Pathway and Promoting IL-10/JAK1/STAT3-Mediated Anti-inflammatory Response.
Aloin Preconditioning Attenuates Hepatic Ischemia/Reperfusion Injury via Inhibiting TLR4/MyD88/NF-κB Signal Pathway In Vivo and In Vitro.
Secretory leukocyte protease inhibitor suppresses HPV E6-expressing HNSCC progression by mediating NF-κB and Akt pathways.
HIV-1-infected cell-derived exosomes promote the growth and progression of cervical cancer.
Antitumor activity of a novel dual functional podophyllotoxin derivative involved PI3K/AKT/mTOR pathway.
ETA-mediated anti-TNF-α therapy ameliorates the phenotype of PCOS model induced by letrozole.
Synergism of cisplatin-oleanolic acid co-loaded calcium carbonate nanoparticles on hepatocellular carcinoma cells for enhanced apoptosis and reduced hepatotoxicity.
Exosomes Derived From Bone Marrow Mesenchymal Stem Cells Inhibit Complement Activation In Rats With Spinal Cord Injury.
Dioscin ameliorates peritoneal fibrosis by inhibiting epithelial-to-mesenchymal transition of human peritoneal mesothelial cells via the TLR4/MyD88/NF-κB signaling pathway.
Hydrocortisone Suppresses Early Paraneoplastic Inflammation And Angiogenesis To Attenuate Early Hepatocellular Carcinoma Progression In Rats.
L-Cysteine-Derived H(2)S Promotes Microglia M2 Polarization via Activation of the AMPK Pathway in Hypoxia-Ischemic Neonatal Mice.
ITGBL1 promotes EMT, invasion and migration by activating NF-κB signaling pathway in prostate cancer.
SIRT4 inhibits the proliferation, migration, and invasion abilities of thyroid cancer cells by inhibiting glutamine metabolism.
Monitoring the Early Antiproliferative Effect of the Analgesic-Antitumor Peptide, BmK AGAP on Breast Cancer Using Intravoxel Incoherent Motion With a Reduced Distribution of Four b-Values.
Nobiletin Inhibits IL-1β-Induced Inflammation in Chondrocytes via Suppression of NF-κB Signaling and Attenuates Osteoarthritis in Mice.
Schisandrin A Inhibits the IL-1β-Induced Inflammation and Cartilage Degradation via Suppression of MAPK and NF-κB Signal Pathways in Rat Chondrocytes.
Gardenia Decoction Prevent Intestinal Mucosal Injury by Inhibiting Pro-inflammatory Cytokines and NF-κB Signaling.
Trimetazidine Attenuates Exhaustive Exercise-Induced Myocardial Injury in Rats via Regulation of the Nrf2/NF-κB Signaling Pathway.
The Therapeutic Effects of Treadmill Exercise on Osteoarthritis in Rats by Inhibiting the HDAC3/NF-KappaB Pathway in vivo and in vitro.
Protective Effects of Dioscin Against Doxorubicin-Induced Hepatotoxicity Via Regulation of Sirt1/FOXO1/NF-κb Signal.
Correction to: Protective effects of dioscin against alcohol‑induced liver injury.
Sedum sarmentosum Bunge extract alleviates inflammation and kidney injury via inhibition of M1-macrophage polarization.
Epstein-Barr virus tegument protein BGLF2 inhibits NF-κB activity by preventing p65 Ser536 phosphorylation.
Liquiritigenin inhibits IL-1β-induced inflammation and cartilage matrix degradation in rat chondrocytes.
Inhibition of MCF-7 breast cancer cell proliferation by a synthetic peptide derived from the C-terminal sequence of Orai channel.
Vanillic acid attenuates cartilage degeneration by regulating the MAPK and PI3K/AKT/NF-κB pathways.
Ginkgo Biloba Extract Inhibits Metastasis and ERK/Nuclear Factor kappa B (NF-κB) Signaling Pathway in Gastric Cancer.
Suppression of miR-143 contributes to overexpression of IL-6, HIF-1α and NF-κB p65 in Cr(VI)-induced human exposure and tumor growth.
Naringin mitigates myocardial strain and the inflammatory response in sepsis-induced myocardial dysfunction through regulation of PI3K/AKT/NF-κB pathway.
Limonin ameliorates ulcerative colitis by regulating STAT3/miR-214 signaling pathway.
AEBP1, a prognostic indicator, promotes colon adenocarcinoma cell growth and metastasis through the NF-κB pathway.
Dioscin attenuates Bleomycin-Induced acute lung injury via inhibiting the inflammatory response in mice.
Semaphorin 4C Promotes Macrophage Recruitment and Angiogenesis in Breast Cancer.
Induction of PGRN by influenza virus inhibits the antiviral immune responses through downregulation of type I interferons signaling.
Disocin prevents postmenopausal atherosclerosis in ovariectomized LDLR-/- mice through a PGC-1α/ERα pathway leading to promotion of autophagy and inhibition of oxidative stress, inflammation and apoptosis.
FNDC5 inhibits foam cell formation and monocyte adhesion in vascular smooth muscle cells via suppressing NFκB-mediated NLRP3 upregulation.
Dehydroepiandrosterone alleviates E. Coli O157:H7-induced inflammation by preventing the activation of p38 MAPK and NF-κB pathways in mice peritoneal macrophages.
γ-Oryzanol alleviates acetaminophen-induced liver injury: roles of modulating AMPK/GSK3β/Nrf2 and NF-κB signaling pathways.
Decreased RIPK1 expression in chondrocytes alleviates osteoarthritis via the TRIF/MyD88-RIPK1-TRAF2 negative feedback loop.
Light-induced Nrf2-/- mice as atrophic age-related macular degeneration model and treatment with nanoceria laden injectable hydrogel.
Synthesis and biological evaluation of (1,2,4)triazole[4,3-a]pyridine derivatives as potential therapeutic agents for concanavalin A-induced hepatitis.
TIPE2 ameliorates lipopolysaccharide-induced apoptosis and inflammation in acute lung injury.
Neuroprotection of Andrographolide Against Microglia-Mediated Inflammatory Injury and Oxidative Damage in PC12 Neurons.
Effect of Intranasal Instillation of Lipopolysaccharide on Lung Development and Its Related Mechanism in Newborn Mice.
Nonviral Delivery of GRIM-19 Gene Inhibits Tumor Growth with Reduced Local and Systemic Complications.
Morin reduces inflammatory responses and alleviates lipid accumulation in hepatocytes.
Downregulation of transgelin 2 promotes breast cancer metastasis by activating the reactive oxygen species/nuclear factor‑κB signaling pathway.
Repression of eEF2K transcription by NF-κB tunes translation elongation to inflammation and dsDNA-sensing.
Porcine Circovirus Type 2 Induces Single Immunoglobulin Interleukin-1 Related Receptor (SIGIRR) Downregulation to Promote Interleukin-1β Upregulation in Porcine Alveolar Macrophage.
Ameliorative effects of echinacoside against spinal cord injury via inhibiting NLRP3 inflammasome signaling pathway.
Deoxynivalenol Induces Intestinal Damage and Inflammatory Response through the Nuclear Factor-κB Signaling Pathway in Piglets.
SPOP inhibits mice pancreatic stellate cell activation by promoting FADD degradation in cerulein-induced chronic pancreatitis.
Response of the maternal hypothalamus to cold stress during late pregnancy in rats.
Regulating glycolysis, the TLR4 signal pathway and expression of RBM3 in mouse liver in response to acute cold exposure.
Adeno-associated virus 9-mediated RNA interference targeting SOCS3 alleviates diastolic heart failure in rats.
PKM2 is the target of proanthocyanidin B2 during the inhibition of hepatocellular carcinoma.
Comparison of the Hepatoprotective Effects of the Three Main Stilbenes from Mulberry Twigs.
Hepatoprotective effects and structure-activity relationship of five flavonoids against lipopolysaccharide/d-galactosamine induced acute liver failure in mice.
MiR-101a ameliorates AngII-mediated hypertensive nephropathy by blockade of TGFβ/Smad3 and NF-κB signalling in a mouse model of hypertension.
NF-κB and Poly (ADP-ribose) Polymerase 1 Form a Positive Feedback Loop that Regulates DNA Repair in Acute Myeloid Leukemia Cells.
Betulinic acid suppresses breast cancer aerobic glycolysis via caveolin-1/NF-κB/c-Myc pathway.
Pharmacological preconditioning with the cellular stress inducer thapsigargin protects against experimental sepsis.
Combinatory FK506 and Minocycline Treatment Alleviates Prion-Induced Neurodegenerative Events via Caspase-Mediated MAPK-NRF2 Pathway.
COMMD7 Regulates NF-κB Signaling Pathway in Hepatocellular Carcinoma Stem-like Cells.
Mucin 1 downregulation impairs the anti-necroptotic effects of glucocorticoids in human bronchial epithelial cells.
In Vitro and In Vivo Anti-Inflammatory Effects of Polyphyllin VII through Downregulating MAPK and NF-κB Pathways.
Downregulation of TIMP2 attenuates sepsis-induced AKI through the NF-κb pathway.
Leonurine alleviates LPS-induced myocarditis through suppressing the NF-кB signaling pathway.
Aspirin targets P4HA2 through inhibiting NF-κB and LMCD1-AS1/let-7g to inhibit tumour growth and collagen deposition in hepatocellular carcinoma.
Effect of Astragalus membranaceus in Ovalbumin-Induced Allergic Rhinitis Mouse Model.
Chlorogenic acid: A potent molecule that protects cardiomyocytes from TNF-α-induced injury via inhibiting NF-κB and JNK signals.
GABAB receptor activation attenuates inflammatory orofacial pain by modulating interleukin-1β in satellite glial cells: Role of NF-κB and MAPK signaling pathways.
Matrine inhibits IL-1β secretion in primary porcine alveolar macrophages through the MyD88/NF-κB pathway and NLRP3 inflammasome.
Suppressive effect mediated by human adipose-derived stem cells on T cells involves the activation of JNK.
Dioscin ameliorates intestinal ischemia/reperfusion injury via adjusting miR-351-5p/MAPK13-mediated inflammation and apoptosis.
LncRNA NKILA regulates endothelium inflammation by controlling a NF-κB/KLF4 positive feedback loop.
miR-196a-5p promotes metastasis of colorectal cancer via targeting IκBα.
Star-related lipid transfer protein 10 (STARD10): a novel key player in alcohol-induced breast cancer progression.
Tumor stem-like cell-derived exosomal RNAs prime neutrophils for facilitating tumorigenesis of colon cancer.
HMGB1-mediated differential response on hippocampal neurotransmitter disorder and neuroinflammation in adolescent male and female mice following cold exposure.
Curcumin relieves depressive-like behaviors via inhibition of the NLRP3 inflammasome and kynurenine pathway in rats suffering from chronic unpredictable mild stress.
Catalpol Inhibits Homocysteine-induced Oxidation and Inflammation via Inhibiting Nox4/NF-κB and GRP78/PERK Pathways in Human Aorta Endothelial Cells.
Silencing of LncRNA steroid receptor RNA activator attenuates polycystic ovary syndrome in mice.
The mitochondrial chaperone Prohibitin 1 negatively regulates interleukin-8 in human liver cancers.
Adipose-derived mesenchymal stem cells ameliorate the inflammatory reaction in CLP-induced septic acute lung injury rats via sTNFR1.
Dihydroartemisinin attenuates lipopolysaccharide‑induced acute lung injury in mice by suppressing NF‑κB signaling in an Nrf2‑dependent manner.
Olean-28,13b-olide 2 plays a role in cisplatin-mediated apoptosis and reverses cisplatin resistance in human lung cancer through multiple signaling pathways.
Activating macrophages for enhanced osteogenic and bactericidal performance by Cu ion release from micro/nano-topographical coating on a titanium substrate.
Rice Protein Exerts Anti-Inflammatory Effect in Growing and Adult Rats via Suppressing NF-κB Pathway.
miR-204-5p Represses Bone Metastasis via Inactivating NF-κB Signaling in Prostate Cancer.
Sal B Alleviates Myocardial Ischemic Injury by Inhibiting TLR4 and the Priming Phase of NLRP3 Inflammasome.
Water-separated part of Chloranthus serratus alleviates lipopolysaccharide- induced RAW264.7 cell injury mainly by regulating the MAPK and Nrf2/HO-1 inflammatory pathways.
Protease-activated receptor 2 (PAR-2) antagonist AZ3451 as a novel therapeutic agent for osteoarthritis.
Deoxynivalenol Induces Inflammatory Injury in IPEC-J2 Cells via NF-κB Signaling Pathway.
KRAB-Zinc Finger Protein ZNF268a Deficiency Attenuates the Virus-Induced Pro-Inflammatory Response by Preventing IKK Complex Assembly.
Dietary resveratrol supplementation inhibits heat stress-induced high-activated innate immunity and inflammatory response in spleen of yellow-feather broilers.
Cysteinyl Leukotriene Receptor 2 is Involved in Inflammation and Neuronal Damage by Mediating Microglia M1/M2 Polarization through NF-κB Pathway.
JLP-centrosome is essential for the microtubule-mediated nucleocytoplasmic transport induced by extracellular stimuli.
Sodium Butyrate Ameliorates Intestinal Injury and Improves Survival in a Rat Model of Cecal Ligation and Puncture-Induced Sepsis.
Inducible LGALS3BP/90K activates antiviral innate immune responses by targeting TRAF6 and TRAF3 complex.
Bilirubin alleviates alum-induced peritonitis through inactivation of NLRP3 inflammasome.
Microglia Activated by Excess Cortisol Induce HMGB1 Acetylation and Neuroinflammation in the Hippocampal DG Region of Mice Following Cold Exposure.
NAC1 Potentiates Cellular Antiviral Signaling by Bridging MAVS and TBK1.
Correction: Total saponins from Rosa laevigata Michx fruit attenuates hepatic steatosis induced by high-fat diet in rats.
Quercetin reduces Streptococcus suis virulence by inhibiting suilysin activity and inflammation.
Restorative effect of modified dioscorea pills on the structure of hippocampal neurovascular unit in an animal model of chronic cerebral hypoperfusion.
MiR-92a contributes to the cardiovascular disease development in diabetes mellitus through NF-κB and downstream inflammatory pathways.
Downregulation of ENDOCAN in myeloid leukemia cells inhibits proliferation and promotes apoptosis by suppressing nuclear factor‑κB activity.
Protective effects of ginsenoside Rk3 against chronic alcohol-induced liver injury in mice through inhibition of inflammation, oxidative stress, and apoptosis.
Activation of the MAPK signaling pathway induces upregulation of pro-apoptotic proteins in the hippocampi of cold stressed adolescent mice.
Rosmarinic acid attenuates inflammatory responses through inhibiting HMGB1/TLR4/NF-κB signaling pathway in a mouse model of Parkinson's disease.
Immunomodulatory effects of an acidic polysaccharide fraction from herbal Gynostemma pentaphyllum tea in RAW264.7 cells.
Thioredoxin-1 Protects Spinal Cord from Demyelination Induced by Methamphetamine through Suppressing Endoplasmic Reticulum Stress and Inflammation.
Magnolol Alleviates Inflammatory Responses and Lipid Accumulation by AMP-Activated Protein Kinase-Dependent Peroxisome Proliferator-Activated Receptor α Activation.
Protective Effects of Costunolide Against D-Galactosamine and Lipopolysaccharide-Induced Acute Liver Injury in Mice.
Necrostatin-1 Attenuates Trauma-Induced Mouse Osteoarthritis and IL-1β Induced Apoptosis via HMGB1/TLR4/SDF-1 in Primary Mouse Chondrocytes.
Anthraquinone Emodin Inhibits Tumor Necrosis Factor Alpha-Induced Calcification of Human Aortic Valve Interstitial Cells via the NF-κB Pathway.
Pretreatment with Lactobacillus reuteri F-9-35 attenuates ethanol-induced gastric injury in rats.
Mesenchymal Stem Cell-Derived Exosomes Reduce A1 Astrocytes via Downregulation of Phosphorylated NFκB P65 Subunit in Spinal Cord Injury.
Alpha-Lipoic Acid Protects Human Aortic Endothelial Cells Against H2O2-Induced Injury and Inhibits Atherosclerosis in Ovariectomized Low Density Lipoprotein Receptor Knock-Out Mice.
Panax notoginseng Saponins Regulate Macrophage Polarization under Hyperglycemic Condition via NF-κB Signaling Pathway.
Neuroprotective Effects of dl-3-n-Butylphthalide against Doxorubicin-Induced Neuroinflammation, Oxidative Stress, Endoplasmic Reticulum Stress, and Behavioral Changes.
Electroacupuncture: A Feasible Sirt1 Promoter Which Modulates Metainflammation in Diet-Induced Obesity Rats.
Losartan Ameliorates Calcium Oxalate-Induced Elevation of Stone-Related Proteins in Renal Tubular Cells by Inhibiting NADPH Oxidase and Oxidative Stress.
HIV-1 Tat increases BAG3 via NF-κB signaling to induce autophagy during HIV-associated neurocognitive disorder.
The Nox1/Nox4 inhibitor attenuates acute lung injury induced by ischemia-reperfusion in mice.
IRAK-M Deficiency Exacerbates Ischemic Neurovascular Injuries in Experimental Stroke Mice.
Inhibition of Connexin 43 Hemichannels Alleviates Cerebral Ischemia/Reperfusion Injury via the TLR4 Signaling Pathway.
Clostridium butyricum protects the epithelial barrier by maintaining tight junction protein expression and regulating microflora in a murine model of dextran sodium sulfate-induced colitis.
Resveratrol induces apoptosis in SGC-7901 gastric cancer cells.
GABAB receptor mediate hippocampal neuroinflammation in adolescent male and female mice after cold expose.
StAR-related lipid transfer domain 11 (STARD11)-mediated ceramide transport mediates extracellular vesicle biogenesis.
Polychlorinated Biphenyl Quinones Promotes Breast Cancer Metastasis through Reactive Oxygen Species-Mediated Nuclear Factor κB-Matrix Metalloproteinase Signaling.
Protective roles of NRF2 signaling pathway in cobalt chloride-induced hypoxic cytotoxicity in human HaCaT keratinocytes.
Activation of AMPK prevents monocrotaline-induced pulmonary arterial hypertension by suppression of NF-κB-mediated autophagy activation.
Microcystin-leucine arginine (MC-LR) induced inflammatory response in bovine sertoli cell via TLR4/NF-kB signaling pathway.
Long non-coding RNA FTH1P3 regulated metastasis and invasion of esophageal squamous cell carcinoma through SP1/NF-kB pathway.
Salvianolic Acid B-Alleviated Angiotensin II Induces Cardiac Fibrosis by Suppressing NF-κB Pathway In Vitro.
Diosmetin Attenuates Akt Signaling Pathway by Modulating Nuclear Factor Kappa-Light-Chain-Enhancer of Activated B Cells (NF-κB)/Inducible Nitric Oxide Synthase (iNOS) in Streptozotocin (STZ)-Induced Diabetic Nephropathy Mice.
REV-ERBα integrates colon clock with experimental colitis through regulation of NF-κB/NLRP3 axis.
Resveratrol inhibits monocrotaline-induced pulmonary arterial remodeling by suppression of SphK1-mediated NF-κB activation.
IL-8 analogue CXCL8 (3-72) K11R/G31P, modulates LPS-induced inflammation via AKT1-NF-kβ and ERK1/2-AP-1 pathways in THP-1 monocytes.
HMGB1 knock-down promoting tumor cells viability and arrest pro-apoptotic proteins via Stat3/NFκB in HepG2 cells.
Inhibition of microRNA-143-3p attenuates myocardial hypertrophy by inhibiting inflammatory response.
(2R,3R)Dihydromyricetin inhibits osteoclastogenesis and bone loss through scavenging LPS-induced oxidative stress and NF-κB and MAPKs pathways activating.
Caffeic acid protects against IL-1β-induced inflammatory responses and cartilage degradation in articular chondrocytes.
Toll-like receptor 4 shRNA attenuates lipopolysaccharide-induced epithelial-mesenchymal transition of intrahepatic biliary epithelial cells in rats.
Interleukin-18 binding protein attenuates lipopolysaccharide-induced acute lung injury in mice via suppression NF-κB and activation Nrf2 pathway.
ACT001 can prevent and reverse tamoxifen resistance in human breast cancer cell lines by inhibiting NF-κB activation.
Macrophages mediate corticotomy-accelerated orthodontic tooth movement.
Schisantherin A alleviated alcohol-induced liver injury by the regulation of alcohol metabolism and NF-kB pathway.
IFI16 regulates HTLV-1 replication through promoting HTLV-1 RTI-induced innate immune responses.
DFMG attenuates the activation of macrophages induced by co‑culture with LPC‑injured HUVE‑12 cells via the TLR4/MyD88/NF‑κB signaling pathway.
MicroRNA-21 Knockout Exacerbates Angiotensin II-Induced Thoracic Aortic Aneurysm and Dissection in Mice With Abnormal Transforming Growth Factor-β-SMAD3 Signaling.
Cardioprotection of CAPE-oNO2 against myocardial ischemia/reperfusion induced ROS generation via regulating the SIRT1/eNOS/NF-κB pathway in vivo and in vitro.
Hepatoprotection of auraptene from peels of citrus fruits against thioacetamide-induced hepatic fibrosis in mice by activating farnesoid X receptor.
Hesperidin suppresses the migration and invasion of non-small cell lung cancer cells by inhibiting the SDF-1/CXCR-4 pathway.
Inhibition of transient receptor potential melastatin 8 alleviates airway inflammation and remodeling in a murine model of asthma with cold air stimulus.
Oxyresveratrol prevents lipopolysaccharide/d-galactosamine-induced acute liver injury in mice.
Nicotine-Induced Neuroprotection against Cognitive Dysfunction after Partial Hepatectomy Involves Activation of BDNF/TrkB Signaling Pathway and Inhibition of NF-κB Signaling Pathway in Aged Rats.
Src Promotes Metastasis of Human Non-Small Cell Lung Cancer Cells through Fn14-Mediated NF-κB Signaling.
Synergistic Effects of Salvianolic Acid B and Puerarin on Cerebral Ischemia Reperfusion Injury.
Abberent expression of NOR1 protein in tumor associated macrophages contributes to the development of DEN-induced hepatocellular carcinoma.
Butyrolactone-I from Coral-Derived Fungus Aspergillus terreus Attenuates Neuro-Inflammatory Response via Suppression of NF-κB Pathway in BV-2 Cells.
Exosomes released by hepatocarcinoma cells endow adipocytes with tumor-promoting properties.
Gelofusine Attenuates Tubulointerstitial Injury Induced by cRGD-Conjugated siRNA by Regulating the TLR3 Signaling Pathway.
BST2 promotes cell proliferation, migration and induces NF-κB activation in gastric cancer.
Isosteviol ameliorates diabetic cardiomyopathy in rats by inhibiting ERK and NF-κB signaling pathways.
Subcutaneous administration of infliximab-attenuated silica-induced lung fibrosis.
Macrophages confer resistance to PI3K inhibitor GDC-0941 in breast cancer through the activation of NF-κB signaling.
Prenatal cold stress: Effect on maternal hippocampus and offspring behavior in rats.
Tropisetron attenuates lipopolysaccharide induced neuroinflammation by inhibiting NF-κB and SP/NK1R signaling pathway.
Aspirin is Involved in the Cell Cycle Arrest, Apoptosis, Cell Migration, and Invasion of Oral Squamous Cell Carcinoma.
Dietary restriction delays the secretion of senescence associated secretory phenotype by reducing DNA damage response in the process of renal aging.
Protective effect of dioscin against thioacetamide-induced acute liver injury via FXR/AMPK signaling pathway in vivo.
Anticancer effect of SZC015 on pancreatic cancer via mitochondria-dependent apoptosis and the constitutive suppression of activated nuclear factor κB and STAT3 in vitro and in vivo.
Proteasome Inhibitor Carbobenzoxy-L-Leucyl-L-Leucyl-L-Leucinal (MG132) Enhances Therapeutic Effect of Paclitaxel on Breast Cancer by Inhibiting Nuclear Factor (NF)-κB Signaling.
Hepatoprotective effects of ethyl pyruvate against CCl4-induced hepatic fibrosis via inhibition of TLR4/NF-κB signaling and up-regulation of MMPs/TIMPs ratio.
Functional Role of SUV39H1 in Human Renal Tubular Epithelial Cells Under High-glucose Ambiance.
Editor's Highlight: Effects of Intraperitoneal Injection of SnS2 Flowers on Mouse Testicle.
Protective effects of dioscin against systemic inflammatory response syndromevia adjusting TLR2/MyD88/NF‑κb signal pathway.
Asiatic acid from Potentilla chinensis alleviates non-alcoholic fatty liver by regulating endoplasmic reticulum stress and lipid metabolism.
Bidirectional effects of moxifloxacin on the pro‑inflammatory response in lipopolysaccharide‑stimulated mouse peritoneal macrophages.
CAPE-pNO2 attenuates diabetic cardiomyopathy through the NOX4/NF-κB pathway in STZ-induced diabetic mice.
Correlation between the expression of IL‑18 and deep venous thrombosis.
MEL-pep, an analog of melittin, disrupts cell membranes and reverses 5-fluorouracil resistance in human hepatocellular carcinoma cells.
NOD2 promotes dopaminergic degeneration regulated by NADPH oxidase 2 in 6-hydroxydopamine model of Parkinson's disease.
Cold atmospheric plasma conveys selectivity on triple negative breast cancer cells both in vitro and in vivo.
Renal ischemia-reperfusion injury attenuated by splenic ischemic preconditioning.
LPS‑induced proinflammatory cytokine expression in human airway epithelial cells and macrophages via NF‑κB, STAT3 or AP‑1 activation.
Bergenin, Acting as an Agonist of PPARγ, Ameliorates Experimental Colitis in Mice through Improving Expression of SIRT1, and Therefore Inhibiting NF-κB-Mediated Macrophage Activation.
Carnosic Acid Alleviates BDL-Induced Liver Fibrosis through miR-29b-3p-Mediated Inhibition of the High-Mobility Group Box 1/Toll-Like Receptor 4 Signaling Pathway in Rats.
TET2 Protects against oxLDL-Induced HUVEC Dysfunction by Upregulating the CSE/H2S System.
Protective Effects of Dioscin against Lipopolysaccharide-Induced Acute Lung Injury through Inhibition of Oxidative Stress and Inflammation.
Iridoids with Genipin Stem Nucleus Inhibit Lipopolysaccharide-Induced Inflammation and Oxidative Stress by Blocking the NF-κB Pathway in Polycystic Ovary Syndrome.
Metformin Sensitizes Non-small Cell Lung Cancer Cells to an Epigallocatechin-3-Gallate (EGCG) Treatment by Suppressing the Nrf2/HO-1 Signaling Pathway.
Collagen gel protects L929 cells from TNFα-induced death by activating NF-κB.
MicroRNA-27a/b mediates endothelin-1-induced PPARγ reduction and proliferation of pulmonary artery smooth muscle cells.
Mechanism of Lycium barbarum polysaccharides on primary cultured rat hippocampal neurons.
Anti-inflammatory activity of coptisine free base in mice through inhibition of NF-κB and MAPK signaling pathways.
Interleukin-17A Plays the Same Role on Mice Acute Lung Injury Respectively Induced by Lipopolysaccharide and Paraquat.
Anti-inflammatory capacity of Lactobacillus rhamnosus GG in monophasic variant Salmonella infected piglets is correlated with impeding NLRP6-mediated host inflammatory responses.
Ku70 Senses HTLV-1 DNA and Modulates HTLV-1 Replication.
Schisantherin A attenuates ischemia/reperfusion-induced neuronal injury in rats via regulation of TLR4 and C5aR1 signaling pathways.
Hepatoprotective effect of quercetin against LPS/d-GalN induced acute liver injury in mice by inhibiting the IKK/NF-κB and MAPK signal pathways.
The effect of Astragaloside IV on ethanol-induced gastric mucosal injury in rats: Involvement of inflammation.
Lymphotoxins Promote the Progression of Human Lymphatic Malformation by Enhancing Lymphatic Endothelial Cell Proliferation.
Steroidogenic Acute Regulatory Protein (StAR) Overexpression Reduces Inflammation and Insulin Resistance in Obese Mice.
Comparative study of macrophages in naked mole rats and ICR mice.
miR-221/222 promote cancer stem-like cell properties and tumor growth of breast cancer via targeting PTEN and sustained Akt/NF-κB/COX-2 activation.
Antioxidation, anti-inflammation and anti-apoptosis by paeonol in LPS/d-GalN-induced acute liver failure in mice.
6-Gingerol protects intestinal barrier from ischemia/reperfusion-induced damage via inhibition of p38 MAPK to NF-κB signalling.
Diosmetin exerts anti-oxidative, anti-inflammatory and anti-apoptotic effects to protect against endotoxin-induced acute hepatic failure in mice.
ZNF545 suppresses human hepatocellular carcinoma growth by inhibiting NF-kB signaling.
RelA/p65 inhibition prevents tendon adhesion by modulating inflammation, cell proliferation, and apoptosis.
Chemical characterization of a novel polysaccharide ASKP-1 from Artemisia sphaerocephala Krasch seed and its macrophage activation via MAPK, PI3k/Akt and NF-κB signaling pathways in RAW264.7 cells.
TNF-α stimulates endothelial palmitic acid transcytosis and promotes insulin resistance.
Simvastatin Inhibits IL-1β-Induced Apoptosis and Extracellular Matrix Degradation by Suppressing the NF-kB and MAPK Pathways in Nucleus Pulposus Cells.
Chronic obstructive sleep apnea promotes aortic remodeling in canines through miR-145/Smad3 signaling pathway.
p62/SQSTM1 as an oncotarget mediates cisplatin resistance through activating RIP1-NF-κB pathway in human ovarian cancer cells.
Cytoplasmic fragment of CD147 generated by regulated intramembrane proteolysis contributes to HCC by promoting autophagy.
Long non-coding RNA HOXA-AS2 promotes proliferation and invasion of breast cancer by acting as a miR-520c-3p sponge.
Oncogenic miR-210-3p promotes prostate cancer cell EMT and bone metastasis via NF-κB signaling pathway.
Glucocorticoid-Induced Leucine Zipper Protects the Retina From Light-Induced Retinal Degeneration by Inducing Bcl-xL in Rats.
Contrast Media-Induced Renal Inflammation Is Mediated Through HMGB1 and Its Receptors in Human Tubular Cells.
Knockdown of TREM-1 suppresses IL-1β-induced chondrocyte injury via inhibiting the NF-κB pathway.
KRAS/NF-κB/YY1/miR-489 Signaling Axis Controls Pancreatic Cancer Metastasis.
Glucocorticoid-Induced Leucine Zipper Suppresses ICAM-1 and MCP-1 Expression by Dephosphorylation of NF-κB p65 in Retinal Endothelial Cells.
TRAIL facilitates cytokine expression and macrophage migration during hypoxia/reoxygenation via ER stress-dependent NF-κB pathway.
Multiple UBXN family members inhibit retrovirus and lentivirus production and canonical NFκΒ signaling by stabilizing IκBα.
Heparanase-driven inflammation from the AGEs-stimulated macrophages changes the functions of glomerular endothelial cells.
Calcitriol Ameliorates AngiotensinII-Induced Renal Injury Partly via Upregulating A20.
The inflammatory responses in Cu-mediated elemental imbalance is associated with mitochondrial fission and intrinsic apoptosis in Gallus gallus heart.
Downregulation of miR-141-3p promotes bone metastasis via activating NF-κB signaling in prostate cancer.
Impact of prenatal cold stress on placental physiology, inflammatory response, and apoptosis in rats.
CAPE-pNO2 ameliorated diabetic nephropathy through regulating the Akt/NF-κB/ iNOS pathway in STZ-induced diabetic mice.
The p53-inducible long noncoding RNA TRINGS protects cancer cells from necrosis under glucose starvation.
Chlorogenic acid prevents inflammatory responses in IL‑1β‑stimulated human SW‑1353 chondrocytes, a model for osteoarthritis.
Vascular protective effects of aqueous extracts of Tribulus terrestris on hypertensive endothelial injury.
Phosphocreatine protects endothelial cells from Methylglyoxal induced oxidative stress and apoptosis via the regulation of PI3K/Akt/eNOS and NF-κB pathway.
Isoquercetin Ameliorates Cerebral Impairment in Focal Ischemia Through Anti-Oxidative, Anti-Inflammatory, and Anti-Apoptotic Effects in Primary Culture of Rat Hippocampal Neurons and Hippocampal CA1 Region of Rats.
MicroRNA-3178 ameliorates inflammation and gastric carcinogenesis promoted by Helicobacter pylori new toxin, Tip-α, by targeting TRAF3.
Early Minocycline and Late FK506 Treatment Improves Survival and Alleviates Neuroinflammation, Neurodegeneration, and Behavioral Deficits in Prion-Infected Hamsters.
Targeting NF-kB signaling with polymeric hybrid micelles that co-deliver siRNA and dexamethasone for arthritis therapy.
Low-intensity pulsed ultrasound (LIPUS) prevents periprosthetic inflammatory loosening through FBXL2-TRAF6 ubiquitination pathway.
Anti-inflammatory effect of combined tetramethylpyrazine, resveratrol and curcumin in vivo.
Herpes Simplex Virus 1 UL24 Abrogates the DNA Sensing Signal Pathway by Inhibiting NF-κB Activation.
Yin-Chen-Hao Tang Attenuates Severe Acute Pancreatitis in Rat: An Experimental Verification of In silico Network Target Prediction.
Daphnetin Protects against Cerebral Ischemia/Reperfusion Injury in Mice via Inhibition of TLR4/NF-κB Signaling Pathway.
Protective effects of Astragalus polysaccharides against endothelial dysfunction in hypertrophic rats induced by isoproterenol.
Oral kanglaite injection (KLTI) attenuates the lung cancer-promoting effect of high-fat diet (HFD)-induced obesity.
miR-34a and its novel target, NLRC5, are associated with HPV16 persistence.
Downregulation of DNA-PKcs suppresses P-gp expression via inhibition of the Akt/NF-κB pathway in CD133-positive osteosarcoma MG-63 cells.
Novel recombinant protein FlaA N/C increases tumor radiosensitivity via NF-κB signaling in murine breast cancer cells.
Neuroprotective effects of Kaempferide-7-O-(4″-O-acetylrhamnosyl)-3-O-rutinoside on cerebral ischemia-reperfusion injury in rats.
Dioscin attenuates gastric ischemia/reperfusion injury through the down-regulation of PKC/ERK1/2 signaling via PKCα and PKCβ2 inhibition.
Cleavage and polyadenylation specific factor 4 targets NF-κB/cyclooxygenase-2 signaling to promote lung cancer growth and progression.
Charaterization and immunomodulatory activities of polysaccharide isolated from Pleurotus eryngii.
Anticancer effect of SZC015 on lung cancer cells through ROS-dependent apoptosis and autophagy induction mechanisms in vitro.
Age-associated up-regulation of EGR1 promotes granulosa cell apoptosis during follicle atresia in mice through the NF-κB pathway.
Alpha-lipoic acid defends homocysteine-induced endoplasmic reticulum and oxidative stress in HAECs.
Inhibitory effects of S-allylmercaptocysteine against benzo(a)pyrene-induced precancerous carcinogenesis in human lung cells.
Histone deacetylase inhibitor SAHA attenuates post-seizure hippocampal microglia TLR4/MYD88 signaling and inhibits TLR4 gene expression via histone acetylation.
The role of glycogen synthase kinase-3β (GSK-3β) in endometrial carcinoma: A carcinogenesis, progression, prognosis, and target therapy marker.
The ORF3 Protein of Genotype 1 Hepatitis E Virus Suppresses TLR3-induced NF-κB Signaling via TRADD and RIP1.
Human Bocavirus NS1 and NS1-70 Proteins Inhibit TNF-α-Mediated Activation of NF-κB by targeting p65.
DYT-40, a novel synthetic 2-styryl-5-nitroimidazole derivative, blocks malignant glioblastoma growth and invasion by inhibiting AEG-1 and NF-κB signaling pathways.
Increased mitochondrial fission promotes autophagy and hepatocellular carcinoma cell survival through the ROS-modulated coordinated regulation of the NFKB and TP53 pathways.
Dioscin alleviates dimethylnitrosamine-induced acute liver injury through regulating apoptosis, oxidative stress and inflammation.
Dioscin reduces lipopolysaccharide-induced inflammatory liver injury via regulating TLR4/MyD88 signal pathway.
The Involvement of Protease Nexin-1 (PN1) in the Pathogenesis of Intervertebral Disc (IVD) Degeneration.
Protective Effect of the Total Flavonoids from Rosa laevigata Michx Fruit on Renal Ischemia-Reperfusion Injury through Suppression of Oxidative Stress and Inflammation.
CD147 promotes IKK/IκB/NF-κB pathway to resist TNF-induced apoptosis in rheumatoid arthritis synovial fibroblasts.
Tetrachlorobenzoquinone exhibits neurotoxicity by inducing inflammatory responses through ROS-mediated IKK/IκB/NF-κB signaling.
Novel Recombinant Protein FlaA N/C Protects against Radiation Injury via NF-κB Signaling.
Dendrobium officinale Kimura et Migo attenuates diabetic cardiomyopathy through inhibiting oxidative stress, inflammation and fibrosis in streptozotocin-induced mice.
The role of STIM1 in the Cr(vi)-induced [Ca2+]i increase and cell injury in L-02 hepatocytes.
Polysaccharides from Acanthopanax senticosus enhances intestinal integrity through inhibiting TLR4/NF-κB signaling pathways in lipopolysaccharide-challenged mice.
Salvianolic Acid B Ameliorates Cerebral Ischemia/Reperfusion Injury Through Inhibiting TLR4/MyD88 Signaling Pathway.
Deacetylation of tumor-suppressor MST1 in Hippo pathway induces its degradation through HBXIP-elevated HDAC6 in promotion of breast cancer growth.
Gingerol Reverses the Cancer-Promoting Effect of Capsaicin by Increased TRPV1 Level in a Urethane-Induced Lung Carcinogenic Model.
Astragaloside IV improves the isoproterenol-induced vascular dysfunction via attenuating eNOS uncoupling-mediated oxidative stress and inhibiting ROS-NF-κB pathways.
Long Chain Omega-3 Polyunsaturated Fatty Acid Supplementation Alleviates Doxorubicin-Induced Depressive-Like Behaviors and Neurotoxicity in Rats: Involvement of Oxidative Stress and Neuroinflammation.
Lung tumor exosomes induce a pro-inflammatory phenotype in mesenchymal stem cells via NFκB-TLR signaling pathway.
Knee loading inhibits osteoclast lineage in a mouse model of osteoarthritis.
Inhibition of Hepatocyte Apoptosis: An Important Mechanism of Corn Peptides Attenuating Liver Injury Induced by Ethanol.
Ghrelin Attenuates Liver Fibrosis through Regulation of TGF-β1 Expression and Autophagy.
miRNA-99b-3p functions as a potential tumor suppressor by targeting glycogen synthase kinase-3β in oral squamous cell carcinoma Tca-8113 cells.
Set7 facilitates hepatitis C virus replication via enzymatic activity-dependent attenuation of the IFN-related pathway.
GRP78 is implicated in the modulation of tumor aerobic glycolysis by promoting autophagic degradation of IKKβ.
Protective Effect of the Total Saponins from Rosa laevigata Michx Fruit against Carbon Tetrachloride-Induced Liver Fibrosis in Rats.
Scutellarein inhibits cancer cell metastasis in vitro and attenuates the development of fibrosarcoma in vivo.
Etomidate increases mortality in septic rats through inhibition of nuclear factor kappa-B rather than by causing adrenal insufficiency.
Rhizoma Dioscoreae Nipponicae polysaccharides protect HUVECs from H2O2-induced injury by regulating PPARγ factor and the NADPH oxidase/ROS-NF-κB signal pathway.
Activation of the NF-κB pathway as a mechanism of alcohol enhanced progression and metastasis of human hepatocellular carcinoma.
Potent effects of dioscin against obesity in mice.
Clonorchis sinensis ferritin heavy chain triggers free radicals and mediates inflammation signaling in human hepatic stellate cells.
Anti-inflammation Effects of Oxysophoridine on Cerebral Ischemia-Reperfusion Injury in Mice.
Artificial sweetener neohesperidin dihydrochalcone showed antioxidative, anti-inflammatory and anti-apoptosis effects against paraquat-induced liver injury in mice.
Diallyl trisulfide inhibits naphthalene-induced oxidative injury and the production of inflammatory responses in A549 cells and mice.
DLC-1 induces mitochondrial apoptosis and epithelial mesenchymal transition arrest in nasopharyngeal carcinoma by targeting EGFR/Akt/NF-κB pathway.
Potent effects of dioscin against liver fibrosis.
Sinomenine sensitizes multidrug-resistant colon cancer cells (Caco-2) to doxorubicin by downregulation of MDR-1 expression.
Ethyl pyruvate pretreatment attenuates concanavalin a-induced autoimmune hepatitis in mice.
Salidroside stimulates mitochondrial biogenesis and protects against H₂O₂-induced endothelial dysfunction.
Naringin inhibits TNF-α induced oxidative stress and inflammatory response in HUVECs via Nox4/NF-κ B and PI3K/Akt pathways.
Role of α-lipoic acid in LPS/d-GalN induced fulminant hepatic failure in mice: studies on oxidative stress, inflammation and apoptosis.
Tetrachloro-p-benzoquinone induces hepatic oxidative damage and inflammatory response, but not apoptosis in mouse: the prevention of curcumin.
Effects of the total saponins from Rosa laevigata Michx fruit against acetaminophen-induced liver damage in mice via induction of autophagy and suppression of inflammation and apoptosis.
Protective effects of dioscin against alcohol-induced liver injury.
Fish-oil emulsion (omega-3 polyunsaturated fatty acids) attenuates acute lung injury induced by intestinal ischemia-reperfusion through Adenosine 5'-monophosphate-activated protein kinase-sirtuin1 pathway.
A caspase-dependent pathway is involved in Wnt/β-catenin signaling promoted apoptosis in Bacillus Calmette-Guerin infected RAW264.7 macrophages.
Mulberroside A protects against ischemic impairment in primary culture of rat cortical neurons after oxygen-glucose deprivation followed by reperfusion.
Herpes simplex virus 1 protein kinase US3 hyperphosphorylates p65/RelA and dampens NF-κB activation.
Colistin-induced nephrotoxicity in mice involves the mitochondrial, death receptor, and endoplasmic reticulum pathways.
Salvianolic acid B protects against acute ethanol-induced liver injury through SIRT1-mediated deacetylation of p53 in rats.
Eupolyphaga sinensis walker displays inhibition on hepatocellular carcinoma through regulating cell growth and metastasis signaling.
Interplay between the Notch and PI3K/Akt pathways in high glucose-induced podocyte apoptosis.
Total saponins from Rosa laevigata Michx fruit attenuates hepatic steatosis induced by high-fat diet in rats.
Protective effects of the total saponins from Dioscorea nipponica Makino against carbon tetrachloride-induced liver injury in mice through suppression of apoptosis and inflammation.
Protective effects of neohesperidin dihydrochalcone against carbon tetrachloride-induced oxidative damage in vivo and in vitro.
14-3-3ε mediates the cell fate decision-making pathways in response of hepatocellular carcinoma to Bleomycin-induced DNA damage.
Ethyl pyruvate ameliorates hepatic ischemia-reperfusion injury by inhibiting intrinsic pathway of apoptosis and autophagy.
Fluoride-elicited developmental testicular toxicity in rats: roles of endoplasmic reticulum stress and inflammatory response.
Protective effect of flavonoid-rich extract from Rosa laevigata Michx on cerebral ischemia-reperfusion injury through suppression of apoptosis and inflammation.
Salvianolic acid A preconditioning confers protection against concanavalin A-induced liver injury through SIRT1-mediated repression of p66shc in mice.
Protection of the flavonoid fraction from Rosa laevigata Michx fruit against carbon tetrachloride-induced acute liver injury in mice.
The hepatitis B virus X protein downregulates NF-κB signaling pathways through decreasing the Notch signaling pathway in HBx-transformed L02 cells.
MG132-mediated inhibition of the ubiquitin-proteasome pathway ameliorates cancer cachexia.
Herpes simplex virus 1 E3 ubiquitin ligase ICP0 protein inhibits tumor necrosis factor alpha-induced NF-κB activation by interacting with p65/RelA and p50/NF-κB1.
Isoquercetin protects cortical neurons from oxygen-glucose deprivation-reperfusion induced injury via suppression of TLR4-NF-кB signal pathway.
Protective effects of the total saponins from Rosa laevigata Michx fruit against carbon tetrachloride-induced acute liver injury in mice.
Astragaloside IV attenuates inflammatory cytokines by inhibiting TLR4/NF-кB signaling pathway in isoproterenol-induced myocardial hypertrophy.
Herpes simplex virus 1 DNA polymerase processivity factor UL42 inhibits TNF-α-induced NF-κB activation by interacting with p65/RelA and p50/NF-κB1.
Downregulation of nucleoporin 88 and 214 induced by oridonin may protect OCIM2 acute erythroleukemia cells from apoptosis through regulation of nucleocytoplasmic transport of NF-κB.
Overexpression of steroidogenic acute regulatory protein in rat aortic endothelial cells attenuates palmitic acid-induced inflammation and reduction in nitric oxide bioavailability.
Nuclear factor-kappa B activity regulates brain expression of P-glycoprotein in the kainic acid-induced seizure rats.
Shikonin, a Chinese plant-derived naphthoquinone, induces apoptosis in hepatocellular carcinoma cells through reactive oxygen species: A potential new treatment for hepatocellular carcinoma.
Wu Y, Zhao L, Gu L, Tilyek A, Yu B, Chai C
Journal of ethnopharmacology 2022 Jan 30;283:114696
Journal of ethnopharmacology 2022 Jan 30;283:114696
Bombyx mori Akirin hijacks a viral peptide vSP27 encoded by BmCPV circRNA and activates the ROS-NF-κB pathway against viral infection.
Zhang Y, Zhang X, Dai K, Zhu M, Liang Z, Pan J, Zhang Z, Xue R, Cao G, Hu X, Gong C
International journal of biological macromolecules 2022 Jan 1;194:223-232
International journal of biological macromolecules 2022 Jan 1;194:223-232
Therapeutic effect of and mechanisms underlying the effect of miR-195-5p on subarachnoid hemorrhage-induced vasospasm and brain injury in rats.
Tsai TH, Chang CH, Lin SH, Su YF, Tsai YC, Yang SF, Lin CL
PeerJ 2021;9:e11395
PeerJ 2021;9:e11395
An Inhibitor of NF-κB and an Agonist of AMPK: Network Prediction and Multi-Omics Integration to Derive Signaling Pathways for Acteoside Against Alzheimer's Disease.
Li YQ, Chen Y, Jiang SQ, Shi YY, Jiang XL, Wu SS, Zhou P, Wang HY, Li P, Li F
Frontiers in cell and developmental biology 2021;9:652310
Frontiers in cell and developmental biology 2021;9:652310
Electroacupuncture Reduces Oocyte Number and Maintains Vascular Barrier Against Ovarian Hyperstimulation Syndrome by Regulating CD200.
Chen L, Huang X, Wang L, Wang C, Tang X, Gu M, Jing J, Ma R, Ge X, Yao B
Frontiers in cell and developmental biology 2021;9:648578
Frontiers in cell and developmental biology 2021;9:648578
Nuclear Factor Kappa-B/Homeobox A9-Mediated Modulation of Leucine-Rich Repeat Flightless-Interacting Protein 1 Is Involved in Advanced Glycation End Product-Induced Endothelial Dysfunction.
Zhu Q, Hu S, He Y, Qiu C, Chen T, He Y, Wu Z, Tian L, Shang T, Xiang Y, Zhang H, Li D
Journal of vascular research 2021;58(5):311-320
Journal of vascular research 2021;58(5):311-320
Chemerin promotes microangiopathy in diabetic retinopathy via activation of ChemR23 in rat primary microvascular endothelial cells.
Jun L, Lin-Lin S, Hui S
Molecular vision 2021;27:575-587
Molecular vision 2021;27:575-587
Exploring the Oxidative Stress Mechanism of Buyang Huanwu Decoction in Intervention of Vascular Dementia Based on Systems Biology Strategy.
Yang K, Zeng L, Ge A, Yi Y, Wang S, Ge J
Oxidative medicine and cellular longevity 2021;2021:8879060
Oxidative medicine and cellular longevity 2021;2021:8879060
Yixintongmai Inhibits Proliferation and Migration and Promotes Apoptosis of Vascular Smooth Muscle Cells Cultured with High Glucose.
Guo J, Zhao D, Dong P
Evidence-based complementary and alternative medicine : eCAM 2021;2021:6583086
Evidence-based complementary and alternative medicine : eCAM 2021;2021:6583086
BMSCs Regulate Astrocytes through TSG-6 to Protect the Blood-Brain Barrier after Subarachnoid Hemorrhage.
Wan Y, Song M, Xie X, Chen Z, Gao Z, Wu X, Huang R, Chen M
Mediators of inflammation 2021;2021:5522291
Mediators of inflammation 2021;2021:5522291
Zanthoxylum bungeanum Seed Oil Attenuates LPS-Induced BEAS-2B Cell Activation and Inflammation by Inhibiting the TLR4/MyD88/NF-κB Signaling Pathway.
Hou J, Wang J, Meng J, Zhang X, Niu Y, Gao J, Bai Y, Zhou J
Evidence-based complementary and alternative medicine : eCAM 2021;2021:2073296
Evidence-based complementary and alternative medicine : eCAM 2021;2021:2073296
Downregulation of m6A Reader YTHDC2 Promotes the Proliferation and Migration of Malignant Lung Cells via CYLD/NF-κB Pathway.
Wang J, Tan L, Jia B, Yu X, Yao R, OUYang N, Yu X, Cao X, Tong J, Chen T, Chen R, Li J
International journal of biological sciences 2021;17(10):2633-2651
International journal of biological sciences 2021;17(10):2633-2651
Network Pharmacology Analysis of the Mechanisms of Compound Herba Sarcandrae (Fufang Zhongjiefeng) Aerosol in Chronic Pharyngitis Treatment.
Zhang Y, Yuan T, Li Y, Wu N, Dai X
Drug design, development and therapy 2021;15:2783-2803
Drug design, development and therapy 2021;15:2783-2803
The Spinal α7-Nicotinic Acetylcholine Receptor Contributes to the Maintenance of Cancer-Induced Bone Pain.
Yang T, Zhou Y, Zhang W, Zhang L, Chen S, Chen C, Gao F, Yang H, Manyande A, Wang J, Tian Y, Tian X
Journal of pain research 2021;14:441-452
Journal of pain research 2021;14:441-452
Bone Autophagy: A Potential Way of Exercise-Mediated Meg3/P62/Runx2 Pathway to Regulate Bone Formation in T2DM Mice.
Chen X, Yang K, Jin X, Meng Z, Liu B, Yu H, Lu P, Wang K, Fan Z, Tang Z, Zhang F, Liu C
Diabetes, metabolic syndrome and obesity : targets and therapy 2021;14:2753-2764
Diabetes, metabolic syndrome and obesity : targets and therapy 2021;14:2753-2764
BCI Suppresses RANKL-Mediated Osteoclastogenesis and Alleviates Ovariectomy-Induced Bone Loss.
Cai C, Hu W, Zhang Y, Hu X, Yang S, Qiu H, Wang R, Ma M, Qiu Y, Chu T
Frontiers in pharmacology 2021;12:772540
Frontiers in pharmacology 2021;12:772540
Aspartate Metabolism Facilitates IL-1β Production in Inflammatory Macrophages.
Wang H, Zheng X, Liu B, Xia Y, Xin Z, Deng B, He L, Deng J, Ren W
Frontiers in immunology 2021;12:753092
Frontiers in immunology 2021;12:753092
Negative Regulation of RNF90 on RNA Virus-Triggered Antiviral Immune Responses Targeting MAVS.
Yang B, Zhang G, Qin X, Huang Y, Ren X, Sun J, Ma S, Liu Y, Song D, Liu Y, Cui Y, Wang H, Wang J
Frontiers in immunology 2021;12:730483
Frontiers in immunology 2021;12:730483
Chlorogenic Acid Improves NAFLD by Regulating gut Microbiota and GLP-1.
Shi A, Li T, Zheng Y, Song Y, Wang H, Wang N, Dong L, Shi H
Frontiers in pharmacology 2021;12:693048
Frontiers in pharmacology 2021;12:693048
Selonsertib Alleviates the Progression of Rat Osteoarthritis: An in vitro and in vivo Study.
Yan J, Zhang Y, Sheng G, Ni B, Xiao Y, Wang S, Wang T, Ma Y, Wang H, Wu H, Tu C
Frontiers in pharmacology 2021;12:687033
Frontiers in pharmacology 2021;12:687033
Cronobacter sakazakii ATCC 29544 Translocated Human Brain Microvascular Endothelial Cells via Endocytosis, Apoptosis Induction, and Disruption of Tight Junction.
Jin T, Guan N, Du Y, Zhang X, Li J, Xia X
Frontiers in microbiology 2021;12:675020
Frontiers in microbiology 2021;12:675020
Effect of Protein O-Mannosyltransferase (MSMEG_5447) on M. smegmatis and Its Survival in Macrophages.
Jia L, Sha S, Yang S, Taj A, Ma Y
Frontiers in microbiology 2021;12:657726
Frontiers in microbiology 2021;12:657726
Astragalin Inhibits the Proliferation and Migration of Human Colon Cancer HCT116 Cells by Regulating the NF-κB Signaling Pathway.
Yang M, Li WY, Xie J, Wang ZL, Wen YL, Zhao CC, Tao L, Li LF, Tian Y, Sheng J
Frontiers in pharmacology 2021;12:639256
Frontiers in pharmacology 2021;12:639256
Hepatitis B Surface Antigen Suppresses the Activation of Nuclear Factor Kappa B Pathway via Interaction With the TAK1-TAB2 Complex.
Deng F, Xu G, Cheng Z, Huang Y, Ma C, Luo C, Yu C, Wang J, Xu X, Liu S, Zhu Y
Frontiers in immunology 2021;12:618196
Frontiers in immunology 2021;12:618196
Experimental and clinical evidence suggests that GRPEL2 plays an oncogenic role in HCC development.
Lai MC, Zhu QQ, Xu J, Zhang WJ
American journal of cancer research 2021;11(9):4175-4198
American journal of cancer research 2021;11(9):4175-4198
CALR-TLR4 Complex Inhibits Non-Small Cell Lung Cancer Progression by Regulating the Migration and Maturation of Dendritic Cells.
Chen R, Huang M, Yang X, Chen XH, Shi MY, Li ZF, Chen ZN, Wang K
Frontiers in oncology 2021;11:743050
Frontiers in oncology 2021;11:743050
TPL Inhibits the Invasion and Migration of Drug-Resistant Ovarian Cancer by Targeting the PI3K/AKT/NF-κB-Signaling Pathway to Inhibit the Polarization of M2 TAMs.
Le F, Yang L, Han Y, Zhong Y, Zhan F, Feng Y, Hu H, Chen T, Tan B
Frontiers in oncology 2021;11:704001
Frontiers in oncology 2021;11:704001
SPNS2 Downregulation Induces EMT and Promotes Colorectal Cancer Metastasis via Activating AKT Signaling Pathway.
Lv L, Yi Q, Yan Y, Chao F, Li M
Frontiers in oncology 2021;11:682773
Frontiers in oncology 2021;11:682773
Yangonin modulates lipid homeostasis, ameliorates cholestasis and cellular senescence in alcoholic liver disease via activating nuclear receptor FXR.
Kong L, Dong R, Huang K, Wang X, Wang D, Yue N, Wang C, Sun P, Gu J, Luo H, Liu K, Wu J, Sun H, Meng Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Sep;90:153629
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Sep;90:153629
Maresin-1 suppresses IL-1β-induced MMP-13 secretion by activating the PI3K/AKT pathway and inhibiting the NF-κB pathway in synovioblasts of an osteoarthritis rat model with treadmill exercise.
Lu J, Feng X, Zhang H, Wei Y, Yang Y, Tian Y, Bai L
Connective tissue research 2021 Sep;62(5):508-518
Connective tissue research 2021 Sep;62(5):508-518
Salidroside alleviates liver inflammation in furan-induced mice by regulating oxidative stress and endoplasmic reticulum stress.
Yuan Y, Wang Z, Nan B, Yang C, Wang M, Ye H, Xi C, Zhang Y, Yan H
Toxicology 2021 Sep;461:152905
Toxicology 2021 Sep;461:152905
Tumor Necrosis Factor-stimulated Gene-6 (TSG-6) Secreted by BMSCs Regulates Activated Astrocytes by Inhibiting NF-κB Signaling Pathway to Ameliorate Blood Brain Barrier Damage After Intracerebral Hemorrhage.
Tang B, Song M, Xie X, Le D, Tu Q, Wu X, Chen M
Neurochemical research 2021 Sep;46(9):2387-2402
Neurochemical research 2021 Sep;46(9):2387-2402
Long noncoding RNA ANRIL knockdown attenuates neuroinflammation following ischemic stroke via suppressing the expression of NF-κB in vitro and in vivo.
Deng L, Guo Y, Liu J, Chen S, Wang X, Zhao H, Zuo T, Hu Q, Dong Z
Neurological research 2021 Sep;43(9):767-777
Neurological research 2021 Sep;43(9):767-777
Gastrodin protects against high glucose-induced cardiomyocyte toxicity via GSK-3β-mediated nuclear translocation of Nrf2.
Dong Z, Bian L, Wang YL, Sun LM
Human & experimental toxicology 2021 Sep;40(9):1584-1597
Human & experimental toxicology 2021 Sep;40(9):1584-1597
Compound essential oils relieve oxidative stress caused by PM2 .5 exposure by inhibiting autophagy through the AMPK/mTOR pathway.
Ren F, Xu X, Xu J, Mei Y, Zhang J, Wang X, Li F
Environmental toxicology 2021 Sep;36(9):1765-1774
Environmental toxicology 2021 Sep;36(9):1765-1774
Synergy of nanodiamond-doxorubicin conjugates and PD-L1 blockade effectively turns tumor-associated macrophages against tumor cells.
Xu HZ, Li TF, Wang C, Ma Y, Liu Y, Zheng MY, Liu ZJ, Chen JB, Li K, Sun SK, Komatsu N, Xu YH, Zhao L, Chen X
Journal of nanobiotechnology 2021 Sep 6;19(1):268
Journal of nanobiotechnology 2021 Sep 6;19(1):268
Efficient Delivery of Chlorin e6 by Polyglycerol-Coated Iron Oxide Nanoparticles with Conjugated Doxorubicin for Enhanced Photodynamic Therapy of Melanoma.
Li TF, Xu HZ, Xu YH, Yu TT, Tang JM, Li K, Wang C, Peng XC, Li QR, Sang XY, Zheng MY, Liu Y, Zhao L, Chen X
Molecular pharmaceutics 2021 Sep 6;18(9):3601-3615
Molecular pharmaceutics 2021 Sep 6;18(9):3601-3615
Chondroprotective and antiarthritic effects of galangin in osteoarthritis: An in vitro and in vivo study.
Huang X, Pei W, Ni B, Zhang R, You H
European journal of pharmacology 2021 Sep 5;906:174232
European journal of pharmacology 2021 Sep 5;906:174232
Smilax china L. flavonoid alleviates HFHS-induced inflammation by regulating the gut-liver axis in mice.
Li X, Chu L, Liu S, Zhang W, Lin L, Zheng G
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Sep 5;:153728
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Sep 5;:153728
MEST promotes lung cancer invasion and metastasis by interacting with VCP to activate NF-κB signaling.
Wang Y, Zhang J, Li YJ, Yu NN, Liu WT, Liang JZ, Xu WW, Sun ZH, Li B, He QY
Journal of experimental & clinical cancer research : CR 2021 Sep 24;40(1):301
Journal of experimental & clinical cancer research : CR 2021 Sep 24;40(1):301
Arsenic exposure induces intestinal barrier damage and consequent activation of gut-liver axis leading to inflammation and pyroptosis of liver in ducks.
Zhong G, Wan F, Lan J, Jiang X, Wu S, Pan J, Tang Z, Hu L
The Science of the total environment 2021 Sep 20;788:147780
The Science of the total environment 2021 Sep 20;788:147780
TRIM38 protects chondrocytes from IL-1β-induced apoptosis and degeneration via negatively modulating nuclear factor (NF)-κB signaling.
Hu S, Li Y, Wang B, Peng K
International immunopharmacology 2021 Oct;99:108048
International immunopharmacology 2021 Oct;99:108048
Inhibition of TNFAIP1 ameliorates the oxidative stress and inflammatory injury in myocardial ischemia/reperfusion injury through modulation of Akt/GSK-3β/Nrf2 pathway.
Wen L, Yang QH, Ma XL, Li T, Xiao S, Sun CF
International immunopharmacology 2021 Oct;99:107993
International immunopharmacology 2021 Oct;99:107993
Iguratimod decreases bleomycin-induced pulmonary fibrosis in association with inhibition of TNF-α in mice.
Shao S, Qu Z, Liang Y, Xu Y, Zhou D, Li D, Zhang Y, Yin S
International immunopharmacology 2021 Oct;99:107936
International immunopharmacology 2021 Oct;99:107936
Helicobacter pylori infection disturbs the tumor immune microenvironment and is associated with a discrepant prognosis in gastric de novo diffuse large B-cell lymphoma.
Deng Y, Su W, Zhu J, Ji H, Zhou X, Geng J, Zhu J, Zhang Q
Journal for immunotherapy of cancer 2021 Oct;9(10)
Journal for immunotherapy of cancer 2021 Oct;9(10)
Imbalanced inflammatory response in subchronic arsenic-induced liver injury and the protective effects of Ginkgo biloba extract in rats: Potential role of cytokines mediated cell-cell interactions.
Dong L, Liu Y, Wang D, Zhu K, Zou Z, Zhang A
Environmental toxicology 2021 Oct;36(10):2073-2092
Environmental toxicology 2021 Oct;36(10):2073-2092
Therapeutic potential of isobavachalcone, a natural flavonoid, in murine experimental colitis by inhibiting NF-κB p65.
Zhou Y, Zhong B, Min X, Hou Y, Lin L, Wu Q, Shi J, Chen X
Phytotherapy research : PTR 2021 Oct;35(10):5861-5870
Phytotherapy research : PTR 2021 Oct;35(10):5861-5870
Indispensable role of mitochondria in maintaining the therapeutic potential of curcumin in acute kidney injury.
Li L, Liu S, Zhou Y, Zhao M, Wang Y, Wang C, Lou P, Huang R, Ma L, Lu Y, Fu P, Liu J
Journal of cellular and molecular medicine 2021 Oct;25(20):9863-9877
Journal of cellular and molecular medicine 2021 Oct;25(20):9863-9877
Establishment of incontinence-associated dermatitis rat models and assessment of the therapeutic effects of zinc oxide, painless skin protective film and silicone dressing.
Chen G, Huang L, Chen Y, Zheng S, Zhu L, Ding M
Experimental and therapeutic medicine 2021 Oct;22(4):1058
Experimental and therapeutic medicine 2021 Oct;22(4):1058
Myricetin ameliorates ox-LDL-induced HUVECs apoptosis and inflammation via lncRNA GAS5 upregulating the expression of miR-29a-3p.
Bai Y, Liu X, Chen Q, Chen T, Jiang N, Guo Z
Scientific reports 2021 Oct 4;11(1):19637
Scientific reports 2021 Oct 4;11(1):19637
Electroacupuncture restores intestinal mucosal barrier through TLR4/NF-κB p65 pathway in functional dyspepsia-like rats.
Wang D, Zhang J, Yang D, Wang J, Li J, Han Y, Kang Z, Zhang H
Anatomical record (Hoboken, N.J. : 2007) 2021 Oct 29;
Anatomical record (Hoboken, N.J. : 2007) 2021 Oct 29;
Berberine Inhibits MDA-MB-231 Cells as an Agonist of G Protein-Coupled Estrogen Receptor 1.
Qi M, Liu X, Zhou Y, Wang H, Zhao Y, Ren J, Xiang J
International journal of molecular sciences 2021 Oct 24;22(21)
International journal of molecular sciences 2021 Oct 24;22(21)
Cigarette smoking induces aberrant N6-methyladenosine of DAPK2 to promote non-small cell lung cancer progression by activating NF-κB pathway.
Jin M, Li G, Liu W, Wu X, Zhu J, Zhao D, Zeng Z, Xiong M, Song Y, He X, Zhang Q, Hu K
Cancer letters 2021 Oct 10;518:214-229
Cancer letters 2021 Oct 10;518:214-229
Downregulated fat mass and obesity-associated protein inhibits bone resorption and osteoclastogenesis by nuclear factor-kappa B inactivation.
Zhuang J, Ning H, Wang M, Zhao W, Jing Y, Liu X, Zu J, Kong P, Wang X, Sun C, Yan J
Cellular signalling 2021 Nov;87:110137
Cellular signalling 2021 Nov;87:110137
FOXA2 inhibits doxorubicin-induced apoptosis via transcriptionally activating HBP rate-limiting enzyme GFPT1 in HCC cells.
Huang H, Wang Y, Huang T, Wang L, Liu Y, Wu Q, Yu A, Shi M, Wang X, Li W, Zhang J, Liu Y
Journal of physiology and biochemistry 2021 Nov;77(4):625-638
Journal of physiology and biochemistry 2021 Nov;77(4):625-638
Knockdown of ST6Gal-I expression in human hepatocellular carcinoma cells inhibits their exosome-mediated proliferation- and migration-promoting effects.
Wang L, Chen X, Wang L, Wang S, Li W, Liu Y, Zhang J
IUBMB life 2021 Nov;73(11):1378-1391
IUBMB life 2021 Nov;73(11):1378-1391
Protective effect of carvacrol on liver injury in type 2 diabetic db/db mice.
Zhao W, Chen L, Zhou H, Deng C, Han Q, Chen Y, Wu Q, Li S
Molecular medicine reports 2021 Nov;24(5)
Molecular medicine reports 2021 Nov;24(5)
Overexpression of the nucleoporin Nup88 stimulates migration and invasion of HeLa cells.
Makise M, Uchimura R, Higashi K, Mashiki Y, Shiraishi R, Shutoku Y, Kuniyasu A
Histochemistry and cell biology 2021 Nov;156(5):409-421
Histochemistry and cell biology 2021 Nov;156(5):409-421
Th17/IL-17 induces endothelial cell senescence via activation of NF-κB/p53/Rb signaling pathway.
Zhang L, Liu M, Liu W, Hu C, Li H, Deng J, Cao Q, Wang Y, Hu W, Li Q
Laboratory investigation; a journal of technical methods and pathology 2021 Nov;101(11):1418-1426
Laboratory investigation; a journal of technical methods and pathology 2021 Nov;101(11):1418-1426
Discovery of Phenolic Glycoside from Hyssopus cuspidatus Attenuates LPS-Induced Inflammatory Responses by Inhibition of iNOS and COX-2 Expression through Suppression of NF-κB Activation.
Liu X, Su J, Wang G, Zheng L, Wang G, Sun Y, Bao Y, Wang S, Huang Y
International journal of molecular sciences 2021 Nov 9;22(22)
International journal of molecular sciences 2021 Nov 9;22(22)
The histone deacetylase inhibitor belinostat ameliorates experimental autoimmune encephalomyelitis in mice by inhibiting TLR2/MyD88 and HDAC3/ NF-κB p65-mediated neuroinflammation.
Shen Y, Yang R, Zhao J, Chen M, Chen S, Ji B, Chen H, Liu D, Li L, Du G
Pharmacological research 2021 Nov 7;176:105969
Pharmacological research 2021 Nov 7;176:105969
HB-EGF-induced IL-8 secretion from airway epithelium leads to lung fibroblast proliferation and migration.
Li Y, Su G, Zhong Y, Xiong Z, Huang T, Quan J, Huang J, Wen X, Luo C, Zheng W, Chen J, Cheng J, Yao W, Lai T
BMC pulmonary medicine 2021 Nov 6;21(1):347
BMC pulmonary medicine 2021 Nov 6;21(1):347
Allicin Ameliorates Intestinal Barrier Damage via Microbiota-Regulated Short-Chain Fatty Acids-TLR4/MyD88/NF-κB Cascade Response in Acrylamide-Induced Rats.
Yuan Y, Lu L, Bo N, Chaoyue Y, Haiyang Y
Journal of agricultural and food chemistry 2021 Nov 3;69(43):12837-12852
Journal of agricultural and food chemistry 2021 Nov 3;69(43):12837-12852
Mettl3 promotes oxLDL-mediated inflammation through activating STAT1 signaling.
Li Z, Xu Q, Huangfu N, Chen X, Zhu J
Journal of clinical laboratory analysis 2021 Nov 26;:e24019
Journal of clinical laboratory analysis 2021 Nov 26;:e24019
Protection of CAPE-pNO2 Against Chronic Myocardial Ischemia by the TGF-Β1/Galectin-3 Pathway In Vivo and In Vitro.
Wan Q, Zhang L, Zhou Q, Han Y, Li Z, Li B
Inflammation 2021 Nov 24;
Inflammation 2021 Nov 24;
Effects of ribosomal associated protein hnRNP D in gemcitabine-resistant pancreatic cancer.
Wang C, Huang H
Biochemical and biophysical research communications 2021 Nov 19;579:181-187
Biochemical and biophysical research communications 2021 Nov 19;579:181-187
Indole-3-Propionic Acid, a Functional Metabolite of Clostridium sporogenes, Promotes Muscle Tissue Development and Reduces Muscle Cell Inflammation.
Du L, Qi R, Wang J, Liu Z, Wu Z
International journal of molecular sciences 2021 Nov 18;22(22)
International journal of molecular sciences 2021 Nov 18;22(22)
Ripened Pu-Erh Tea Improved the Enterohepatic Circulation in a Circadian Rhythm Disorder Mice Model.
Hu S, Chen Y, Zhao S, Sun K, Luo L, Zeng L
Journal of agricultural and food chemistry 2021 Nov 17;69(45):13533-13545
Journal of agricultural and food chemistry 2021 Nov 17;69(45):13533-13545
TRPV4-induced Müller cell gliosis and TNF-α elevation-mediated retinal ganglion cell apoptosis in glaucomatous rats via JAK2/STAT3/NF-κB pathway.
Li Q, Cheng Y, Zhang S, Sun X, Wu J
Journal of neuroinflammation 2021 Nov 17;18(1):271
Journal of neuroinflammation 2021 Nov 17;18(1):271
Intermittent hypoxia aggravates non-alcoholic fatty liver disease via RIPK3-dependent necroptosis-modulated Nrf2/NFκB signaling pathway.
Zhang H, Zhou L, Zhou Y, Wang L, Jiang W, Liu L, Yue S, Zheng P, Liu H
Life sciences 2021 Nov 15;285:119963
Life sciences 2021 Nov 15;285:119963
Protective effect of the effective part of Andrographis paniculata (Burm.f.) Nees on PM2.5-induced lung injury in rats by modulating the NF-κB pathway.
Yao H, Zhao J, Zhu L, Xie Y, Zhao N, Yao R, Sun H, Han G
Journal of ethnopharmacology 2021 Nov 15;280:114420
Journal of ethnopharmacology 2021 Nov 15;280:114420
Astaxanthin attenuated hyperuricemia and kidney inflammation by inhibiting uric acid synthesis and the NF-κ B/NLRP3 signaling pathways in potassium oxonate and hypoxanthine-induced hyperuricemia mice.
Zhuang J, Zhou X, Liu T, Zhang S, Yuan F, Zhang L, Yang Z, Chen Y
Die Pharmazie 2021 Nov 1;76(11):551-558
Die Pharmazie 2021 Nov 1;76(11):551-558
Protective effect of Apelin/APJ system on lipopolysaccharide-related cardiac dysfunction.
Hu J, Huo S, Dou S, Jiang W, Li Y
General physiology and biophysics 2021 May;40(3):161-171
General physiology and biophysics 2021 May;40(3):161-171
TUFM is involved in Alzheimer's disease-like pathologies that are associated with ROS.
Zhong BR, Zhou GF, Song L, Wen QX, Deng XJ, Ma YL, Hu LT, Chen GJ
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 May;35(5):e21445
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 May;35(5):e21445
Targeted regulation of lymphocytic ER stress response with an overall immunosuppression to alleviate allograft rejection.
Shi Y, Lu Y, Zhu C, Luo Z, Li X, Liu Y, Jiang M, Liu X, Luo L, Du Y, You J
Biomaterials 2021 May;272:120757
Biomaterials 2021 May;272:120757
Proof-of-concept study investigating the role of S100P-RAGE in nasopharyngeal carcinoma.
Wang C, Wang X, Han A, Wang Y, Jiang H
Experimental and therapeutic medicine 2021 May;21(5):470
Experimental and therapeutic medicine 2021 May;21(5):470
Mitochondrial TXN2 attenuates amyloidogenesis via selective inhibition of BACE1 expression.
Li KY, Xiang XJ, Song L, Chen J, Luo B, Wen QX, Zhong BR, Zhou GF, Deng XJ, Ma YL, Hu LT, Chen GJ
Journal of neurochemistry 2021 May;157(4):1351-1365
Journal of neurochemistry 2021 May;157(4):1351-1365
Anti-angiogenesis and anti-metastasis effects of Polyphyllin VII on Hepatocellular carcinoma cells in vitro and in vivo.
Zhang C, Li Q, Qin G, Zhang Y, Li C, Han L, Wang R, Wang S, Chen H, Liu K, He C
Chinese medicine 2021 May 31;16(1):41
Chinese medicine 2021 May 31;16(1):41
Downregulation of CD151 restricts VCAM-1 mediated leukocyte infiltration to reduce neurobiological injuries after experimental stroke.
Gao C, Jia W, Xu W, Wu Q, Wu J
Journal of neuroinflammation 2021 May 22;18(1):118
Journal of neuroinflammation 2021 May 22;18(1):118
Anti-inflammatory activity of the water extract of Chloranthus serratus roots in LPS-stimulated RAW264.7 cells mediated by the Nrf2/HO-1, MAPK and NF-κB signaling pathways.
Sun S, Zhang J, Li H, Du Y, Li S, Li A, Suo X, Wang Y, Sun Q
Journal of ethnopharmacology 2021 May 10;271:113880
Journal of ethnopharmacology 2021 May 10;271:113880
Glucagon-like peptide-1 (GLP-1) improved diabetic lung fibrosis via AMPK and microRNA-27a (miR-27a).
Liu J, Li X, Lu S, Zheng X, Zhang X, Zhao W
Annals of translational medicine 2021 Mar;9(6):492
Annals of translational medicine 2021 Mar;9(6):492
Macrophage regulator of G-protein signaling 12 contributes to inflammatory pain hypersensitivity.
Yuan G, Yang S, Gautam M, Luo W, Yang S
Annals of translational medicine 2021 Mar;9(6):448
Annals of translational medicine 2021 Mar;9(6):448
Triptolide reduces salivary gland damage in a non-obese diabetic mice model of Sjögren's syndrome via JAK/STAT and NF-κB signaling pathways.
Guo Y, Ji W, Lu Y, Wang Y
Journal of clinical biochemistry and nutrition 2021 Mar;68(2):131-138
Journal of clinical biochemistry and nutrition 2021 Mar;68(2):131-138
Hsa_circ_0056558 regulates cyclin-dependent kinase 6 by sponging microRNA-1290 to suppress the proliferation and differentiation in ankylosing spondylitis.
Li X, Zhou W, Li Z, Guan F
Autoimmunity 2021 Mar;54(2):114-128
Autoimmunity 2021 Mar;54(2):114-128
Cordyceps acid alleviates lung cancer in nude mice.
Wang J, Chen H, Li W, Shan L
Journal of biochemical and molecular toxicology 2021 Mar;35(3):e22670
Journal of biochemical and molecular toxicology 2021 Mar;35(3):e22670
Crosstalk between adipocytes and M2 macrophages compensates for osteopenic phenotype in the Lrp5-deficient mice.
Li L, Qiu X, Zhang N, Sun Y, Wang Y, Wang L
Experimental biology and medicine (Maywood, N.J.) 2021 Mar;246(5):572-583
Experimental biology and medicine (Maywood, N.J.) 2021 Mar;246(5):572-583
The miR-623/CXCL12 axis inhibits LPS-induced nucleus pulposus cell apoptosis and senescence.
Zhong H, Zhou Z, Guo L, Liu F, Zheng B, Bi S, Tian C
Mechanisms of ageing and development 2021 Mar;194:111417
Mechanisms of ageing and development 2021 Mar;194:111417
Cardamonin protects nucleus pulposus cells against IL-1β-induced inflammation and catabolism via Nrf2/NF-κB axis.
Xie C, Ma H, Shi Y, Li J, Wu H, Wang B, Shao Z, Huang C, Chen J, Sun L, Zhou Y, Tian N, Wu Y, Gao W, Wu A, Wang X, Zhang X
Food & function 2021 Mar 21;12(6):2703-2714
Food & function 2021 Mar 21;12(6):2703-2714
Clostridium Butyricum ZJU-F1 Benefits the Intestinal Barrier Function and Immune Response Associated with Its Modulation of Gut Microbiota in Weaned Piglets.
Fu J, Wang T, Xiao X, Cheng Y, Wang F, Jin M, Wang Y, Zong X
Cells 2021 Mar 2;10(3)
Cells 2021 Mar 2;10(3)
The MIR155 host gene/microRNA-627/HMGB1/NF-κB loop modulates fibroblast proliferation and extracellular matrix deposition.
Li J, Zhang X, Wang T, Li J, Su Q, Zhong C, Chen Z, Liang Y
Life sciences 2021 Mar 15;269:119085
Life sciences 2021 Mar 15;269:119085
Effect of selenium-enriched kiwifruit on body fat reduction and liver protection in hyperlipidaemic mice.
Zhang X, Xia H, Wang J, Leng R, Zhou X, Gao Q, He K, Liu D, Huang B
Food & function 2021 Mar 15;12(5):2044-2057
Food & function 2021 Mar 15;12(5):2044-2057
A New Perspective on Ameliorating Depression-Like Behaviors: Suppressing Neuroinflammation by Upregulating PGC-1α.
Fu X, Jiao J, Qin T, Yu J, Fu Q, Deng X, Ma S, Ma Z
Neurotoxicity research 2021 Jun;39(3):872-885
Neurotoxicity research 2021 Jun;39(3):872-885
Wogonin alleviates liver injury in sepsis through Nrf2-mediated NF-κB signalling suppression.
Dai JM, Guo WN, Tan YZ, Niu KW, Zhang JJ, Liu CL, Yang XM, Tao KS, Chen ZN, Dai JY
Journal of cellular and molecular medicine 2021 Jun;25(12):5782-5798
Journal of cellular and molecular medicine 2021 Jun;25(12):5782-5798
NF‑κB is negatively associated with Nurr1 to reduce the inflammatory response in Parkinson's disease.
Gao H, Wang D, Jiang S, Mao J, Yang X
Molecular medicine reports 2021 Jun;23(6)
Molecular medicine reports 2021 Jun;23(6)
Virus-inducible IGFALS facilitates innate immune responses by mediating IRAK1 and TRAF6 activation.
Xu G, Deng F, Zuo Q, Liu L, Dou K, Cheng Z, Cao W, Luo C, Yu C, Liu S, Zhu Y
Cellular & molecular immunology 2021 Jun;18(6):1587-1589
Cellular & molecular immunology 2021 Jun;18(6):1587-1589
The N6-methyladenosine RNA-binding protein YTHDF1 modulates the translation of TRAF6 to mediate the intestinal immune response.
Zong X, Xiao X, Shen B, Jiang Q, Wang H, Lu Z, Wang F, Jin M, Min J, Wang F, Wang Y
Nucleic acids research 2021 Jun 4;49(10):5537-5552
Nucleic acids research 2021 Jun 4;49(10):5537-5552
Dexmedetomidine post-conditioning attenuates cerebral ischemia following asphyxia cardiac arrest through down-regulation of apoptosis and neuroinflammation in rats.
Li G, LeiQian, Gu P, Fan D
BMC anesthesiology 2021 Jun 28;21(1):180
BMC anesthesiology 2021 Jun 28;21(1):180
Exosomal SNHG16 secreted by CSCs promotes glioma development via TLR7.
Zhang R, Li P, Lv H, Li N, Ren S, Xu W
Stem cell research & therapy 2021 Jun 16;12(1):349
Stem cell research & therapy 2021 Jun 16;12(1):349
Identification of a Novel TAR RNA-Binding Protein 2 Modulator with Potential Therapeutic Activity against Hepatocellular Carcinoma.
Zhou Z, Li Y, Ma X, Cao B, Peng T, Sheng Y, Peng H, Li R, Cao Y, Xi R, Li F, Wang M, Sun H, Zhang G, Zhang H, Hu K, Xiao W, Wang F
Journal of medicinal chemistry 2021 Jun 10;64(11):7404-7421
Journal of medicinal chemistry 2021 Jun 10;64(11):7404-7421
Inducible ATP1B1 Upregulates Antiviral Innate Immune Responses by the Ubiquitination of TRAF3 and TRAF6.
Cao W, Guo Y, Cheng Z, Xu G, Zuo Q, Nie L, Huang Y, Liu S, Zhu Y
Journal of immunology (Baltimore, Md. : 1950) 2021 Jun 1;206(11):2668-2681
Journal of immunology (Baltimore, Md. : 1950) 2021 Jun 1;206(11):2668-2681
IFI16 directly senses viral RNA and enhances RIG-I transcription and activation to restrict influenza virus infection.
Jiang Z, Wei F, Zhang Y, Wang T, Gao W, Yu S, Sun H, Pu J, Sun Y, Wang M, Tong Q, Gao C, Chang KC, Liu J
Nature microbiology 2021 Jul;6(7):932-945
Nature microbiology 2021 Jul;6(7):932-945
miR-671-5p Attenuates Neuroinflammation via Suppressing NF-κB Expression in an Acute Ischemic Stroke Model.
Deng L, Guo Y, Liu J, Wang X, Chen S, Wang Q, Rao J, Wang Y, Zuo T, Hu Q, Zhao X, Dong Z
Neurochemical research 2021 Jul;46(7):1801-1813
Neurochemical research 2021 Jul;46(7):1801-1813
Effects of medicine food Fructus Gardeniae on liver and kidney functions after oral administration to rats for 12 weeks.
Li C, Gao X, Gao X, Lv J, Bian X, Lv J, Sun J, Luo G, Zhang H
Journal of food biochemistry 2021 Jul;45(7):e13752
Journal of food biochemistry 2021 Jul;45(7):e13752
N-acetylserotonin alleviated the expression of interleukin-1β in retinal ischemia-reperfusion rats via the TLR4/NF-κB/NLRP3 pathway.
Liu J, Zhang N, Zhang M, Yin H, Zhang X, Wang X, Wang X, Zhao Y
Experimental eye research 2021 Jul;208:108595
Experimental eye research 2021 Jul;208:108595
GLP-1R activation ameliorated novel-object recognition memory dysfunction via regulating hippocampal AMPK/NF-κB pathway in neuropathic pain mice.
Zhang LQ, Zhang W, Li T, Yang T, Yuan X, Zhou Y, Zou Q, Yang H, Gao F, Tian Y, Mei W, Tian XB
Neurobiology of learning and memory 2021 Jul;182:107463
Neurobiology of learning and memory 2021 Jul;182:107463
Evolutionary history and functional characterization of Lj-TICAM-a and Lj-TICAM-b formed via lineage-specific tandem duplication in lamprey (Lampetra japonica).
Geng M, Hua Y, Liu Y, Quan J, Hu X, Su P, Li Y, Liu X, Li Q, Zhu T
Genomics 2021 Jul;113(4):2756-2768
Genomics 2021 Jul;113(4):2756-2768
Diterpenoids from the seeds of Euphorbia lathyris and their anti-inflammatory activity.
Wang Y, Song Z, Guo Y, Xie H, Zhang Z, Sun D, Li H, Chen L
Bioorganic chemistry 2021 Jul;112:104944
Bioorganic chemistry 2021 Jul;112:104944
Baicalein Delays H2O2-Induced Astrocytic Senescence through Inhibition of Senescence-Associated Secretory Phenotype (SASP), Suppression of JAK2/STAT1/NF-κB Pathway, and Regulation of Leucine Metabolism.
Gao L, Zheng WG, Wu XK, Du GH, Qin XM
ACS chemical neuroscience 2021 Jul 7;12(13):2320-2335
ACS chemical neuroscience 2021 Jul 7;12(13):2320-2335
Adjuvant treatment and molecular mechanism of probiotic compounds in patients with gastric cancer after gastrectomy.
Zheng C, Chen T, Lu J, Wei K, Tian H, Liu W, Xu T, Wang X, Wang S, Yang R, Yang Y, Liu Z, Wei H, Deng X
Food & function 2021 Jul 21;12(14):6294-6308
Food & function 2021 Jul 21;12(14):6294-6308
Role of IL-6-IL-27 Complex in Host Antiviral Immune Response.
Zuo Q, Cheng Z, Zhang G, Xia Y, Xu G, Cao W, Yang X, Fu Y, He R, Fang P, Guo Y, Nie L, Huang Y, Liu L, Zhan J, Liu S, Zhu Y
Journal of immunology (Baltimore, Md. : 1950) 2021 Jul 15;207(2):577-589
Journal of immunology (Baltimore, Md. : 1950) 2021 Jul 15;207(2):577-589
Physcion 8-O-β-glucopyranoside ameliorates liver fibrosis through inflammation inhibition by regulating SIRT3-mediated NF-κB P65 nuclear expression.
Chen C, Gu J, Wang J, Wu Y, Yang A, Chen T, Zhou T, Liu Z
International immunopharmacology 2021 Jan;90:107206
International immunopharmacology 2021 Jan;90:107206
Limonin ameliorates dextran sulfate sodium-induced chronic colitis in mice by inhibiting PERK-ATF4-CHOP pathway of ER stress and NF-κB signaling.
Song C, Chen J, Li X, Yang R, Cao X, Zhou L, Zhou Y, Ying H, Zhang Q, Sun Y
International immunopharmacology 2021 Jan;90:107161
International immunopharmacology 2021 Jan;90:107161
Amygdalin inhibits TGFβ1-induced activation of hepatic stellate cells (HSCs) in vitro and CCl4-induced hepatic fibrosis in rats in vivo.
Wang R, Zhang D, Tang D, Sun K, Peng J, Zhu W, Yin S, Wu Y
International immunopharmacology 2021 Jan;90:107151
International immunopharmacology 2021 Jan;90:107151
Hyperoside ameliorates the progression of osteoarthritis: An in vitro and in vivo study.
Sun K, Luo J, Jing X, Xiang W, Guo J, Yao X, Liang S, Guo F, Xu T
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Jan;80:153387
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Jan;80:153387
Dexmedetomidine exerts cardioprotective effect through miR-146a-3p targeting IRAK1 and TRAF6 via inhibition of the NF-κB pathway.
He L, Wang Z, Zhou R, Xiong W, Yang Y, Song N, Qian J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jan;133:110993
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jan;133:110993
miR-34a-5p up-regulates the IL-1β/COX2/PGE2 inflammation pathway and induces the release of CGRP via inhibition of SIRT1 in rat trigeminal ganglion neurons.
Zhang H, Zhang XM, Zong DD, Ji XY, Jiang H, Zhang FZ, He SD
FEBS open bio 2021 Jan;11(1):300-311
FEBS open bio 2021 Jan;11(1):300-311
Antioxidant and Immunomodulatory Properties of Partially purified Exopolysaccharide from Lactobacillus Casei Isolated from Chinese Northeast Sauerkraut.
Xu X, Qiao Y, Peng Q, Shi B, Dia VP
Immunological investigations 2021 Jan 8;:1-18
Immunological investigations 2021 Jan 8;:1-18
Diosmetin Ameliorates Nonalcoholic Steatohepatitis through Modulating Lipogenesis and Inflammatory Response in a STAT1/CXCL10-Dependent Manner.
Luo N, Yang C, Zhu Y, Chen Q, Zhang B
Journal of agricultural and food chemistry 2021 Jan 20;69(2):655-667
Journal of agricultural and food chemistry 2021 Jan 20;69(2):655-667
MicroRNA-150 affects endoplasmic reticulum stress via MALAT1-miR-150 axis-mediated NF-κB pathway in LPS-challenged HUVECs and septic mice.
Liu L, Yan LN, Sui Z
Life sciences 2021 Jan 15;265:118744
Life sciences 2021 Jan 15;265:118744
MicroRNA-520c-3p suppresses vascular endothelium dysfunction by targeting RELA and regulating the AKT and NF-κB signaling pathways.
Jiao Y, Zhao D, Gao F, Hu X, Hu X, Li M, Cui Y, Wei X, Xie C, Zhao Y, Gao Y
Journal of physiology and biochemistry 2021 Feb;77(1):47-61
Journal of physiology and biochemistry 2021 Feb;77(1):47-61
Inhibitory activity of narirutin on RBL-2H3 cells degranulation.
Niu L, Wei J, Li X, Jin Y, Shi X
Immunopharmacology and immunotoxicology 2021 Feb;43(1):68-76
Immunopharmacology and immunotoxicology 2021 Feb;43(1):68-76
Paeonol ameliorates CFA-induced inflammatory pain by inhibiting HMGB1/TLR4/NF-κB p65 pathway.
Qiu C, Yang LD, Yu W, Tian DD, Gao MR, Wang WJ, Li XB, Wu YM, Wang M
Metabolic brain disease 2021 Feb;36(2):273-283
Metabolic brain disease 2021 Feb;36(2):273-283
Downregulating lncRNA PRNCR1 ameliorates LPS-induced pulmonary vascular endothelial cell injury by modulating miR-330-5p/TLR4 axis.
Yu Y, Sun H, Zhu L, Ji L, Liu H
Journal of biochemical and molecular toxicology 2021 Feb;35(2):e22644
Journal of biochemical and molecular toxicology 2021 Feb;35(2):e22644
Inflammatory signals induce MUC16 expression in ovarian cancer cells via NF-κB activation.
Liu J, Li L, Luo N, Liu Q, Liu L, Chen D, Cheng Z, Xi X
Experimental and therapeutic medicine 2021 Feb;21(2):163
Experimental and therapeutic medicine 2021 Feb;21(2):163
Exercise reduces hyperlipidemia-induced kidney damage in apolipoprotein E-deficient mice.
Qian C, Yang Q, Guo L, Zhu H, You X, Liu H, Sun Y
Experimental and therapeutic medicine 2021 Feb;21(2):153
Experimental and therapeutic medicine 2021 Feb;21(2):153
Identification of thrombomodulin as a dynamic monitoring biomarker for deep venous thrombosis evolution.
Cheng X, Sun B, Liu S, Li D, Yang X, Zhang Y
Experimental and therapeutic medicine 2021 Feb;21(2):142
Experimental and therapeutic medicine 2021 Feb;21(2):142
Poly(ADP-ribose) polymerase-1 inhibitor ameliorates dextran sulfate sodium-induced colitis in mice by regulating the balance of Th17/Treg cells and inhibiting the NF-κB signaling pathway.
Peng S, Shen L, Tian MX, Li HM, Wang SS
Experimental and therapeutic medicine 2021 Feb;21(2):134
Experimental and therapeutic medicine 2021 Feb;21(2):134
m6A mRNA methylation regulates testosterone synthesis through modulating autophagy in Leydig cells.
Chen Y, Wang J, Xu D, Xiang Z, Ding J, Yang X, Li D, Han X
Autophagy 2021 Feb;17(2):457-475
Autophagy 2021 Feb;17(2):457-475
MSCs-extracellular vesicles attenuated neuroinflammation, synapse damage and microglial phagocytosis after hypoxia-ischemia injury by preventing osteopontin expression.
Xin D, Li T, Chu X, Ke H, Liu D, Wang Z
Pharmacological research 2021 Feb;164:105322
Pharmacological research 2021 Feb;164:105322
Escalating dose-multiple binge methamphetamine treatment elicits neurotoxicity, altering gut microbiota and fecal metabolites in mice.
Chen LJ, Zhi X, Zhang KK, Wang LB, Li JH, Liu JL, Xu LL, Yoshida JS, Xie XL, Wang Q
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Feb;148:111946
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Feb;148:111946
Ripened Pu-erh Tea Extract Promotes Gut Microbiota Resilience against Dextran Sulfate Sodium Induced Colitis.
Huang Y, Yang Q, Mi X, Qiu L, Tao X, Zhang Z, Xia J, Wu Q, Wei H
Journal of agricultural and food chemistry 2021 Feb 24;69(7):2190-2203
Journal of agricultural and food chemistry 2021 Feb 24;69(7):2190-2203
Hypothermic oxygenated perfusion inhibits HECTD3-mediated TRAF3 polyubiquitination to alleviate DCD liver ischemia-reperfusion injury.
Zhou W, Zhong Z, Lin D, Liu Z, Zhang Q, Xia H, Peng S, Liu A, Lu Z, Wang Y, Ye S, Ye Q
Cell death & disease 2021 Feb 24;12(2):211
Cell death & disease 2021 Feb 24;12(2):211
HUCMSCs transplantation combined with ultrashort wave therapy attenuates neuroinflammation in spinal cord injury through NUR77/ NF-κB pathway.
Wang S, Jia Y, Cao X, Feng S, Na L, Dong H, Gao J, Zhang L
Life sciences 2021 Feb 15;267:118958
Life sciences 2021 Feb 15;267:118958
Icariin ameliorates streptozocin-induced diabetic nephropathy through suppressing the TLR4/NF-κB signal pathway.
Qi MY, He YH, Cheng Y, Fang Q, Ma RY, Zhou SJ, Hao JQ
Food & function 2021 Feb 15;12(3):1241-1251
Food & function 2021 Feb 15;12(3):1241-1251
Protection Mechanisms Underlying Oral Administration of Chlorogenic Acid against Cadmium-Induced Hepatorenal Injury Related to Regulating Intestinal Flora Balance.
Ding Y, Li X, Liu Y, Wang S, Cheng D
Journal of agricultural and food chemistry 2021 Feb 10;69(5):1675-1683
Journal of agricultural and food chemistry 2021 Feb 10;69(5):1675-1683
C-X3-C motif chemokine ligand 1/receptor 1 regulates the M1 polarization and chemotaxis of macrophages after hypoxia/reoxygenation injury.
Guo S, Dong L, Li J, Chen Y, Yao Y, Zeng R, Shushakova N, Haller H, Xu G, Rong S
Chronic diseases and translational medicine 2021 Dec;7(4):254-265
Chronic diseases and translational medicine 2021 Dec;7(4):254-265
Simiao Qingwen Baidu decoction inhibits Epstein-Barr virus-induced B lymphoproliferative disease and lytic viral replication.
Yang X, Liu L, Zhang H, Sun X, Yan Y, Ran R
Pharmaceutical biology 2021 Dec;59(1):741-747
Pharmaceutical biology 2021 Dec;59(1):741-747
Bergenin alleviates H2 O2 -induced oxidative stress and apoptosis in nucleus pulposus cells: Involvement of the PPAR-γ/NF-κB pathway.
Zhang G, Wang H, Zhang Q, Zhao Z, Zhu W, Zuo X
Environmental toxicology 2021 Dec;36(12):2541-2550
Environmental toxicology 2021 Dec;36(12):2541-2550
Amelioratory effect of neoandrographolide on myocardial ischemic-reperfusion injury by its anti-inflammatory and anti-apoptotic activities.
Liu Y, Liu Y, Zhang HL, Yu FF, Yin XR, Zhao YF, Ye F, Wu XQ
Environmental toxicology 2021 Dec;36(12):2367-2379
Environmental toxicology 2021 Dec;36(12):2367-2379
Morinda officinalis oligosaccharides alleviate depressive-like behaviors in post-stroke rats via suppressing NLRP3 inflammasome to inhibit hippocampal inflammation.
Li Z, Xu H, Xu Y, Lu G, Peng Q, Chen J, Bi R, Li J, Chen S, Li H, Jin H, Hu B
CNS neuroscience & therapeutics 2021 Dec;27(12):1570-1586
CNS neuroscience & therapeutics 2021 Dec;27(12):1570-1586
Expression and role of interleukin-1β and associated biomarkers in deep vein thrombosis.
Pai RZ, Fang Q, Tian G, Zhu B, Ge X
Experimental and therapeutic medicine 2021 Dec;22(6):1366
Experimental and therapeutic medicine 2021 Dec;22(6):1366
Diterpenoid alkaloids from Delphinium forrestii var. viride and their anti-inflammation activity.
Song Z, Gao C, Jiang Q, Xu J, Xiong L, Liu K, Sun D, Li H, Chen L
Phytochemistry 2021 Dec;192:112971
Phytochemistry 2021 Dec;192:112971
Enriched environment mitigates depressive behavior by changing the inflammatory activation phenotype of microglia in the hippocampus of depression model rats.
Gu JY, Xu YW, Feng LP, Dong J, Zhao LQ, Liu C, Wang HY, Zhang XY, Song C, Wang CH
Brain research bulletin 2021 Dec;177:252-262
Brain research bulletin 2021 Dec;177:252-262
Acetylcholinesterase inhibition with Pyridostigmine attenuates hypertension and neuroinflammation in the paraventricular nucleus in rat model for Preeclampsia.
Issotina Zibrila A, Li Y, Wang Z, Zhao G, Liu H, Leng J, Ahasan Ali M, Ampofo Osei J, Kang YM, Liu J
International immunopharmacology 2021 Dec;101(Pt B):108365
International immunopharmacology 2021 Dec;101(Pt B):108365
ILC2s induce adaptive Th2-type immunity in different stages of tuberculosis through the Notch-GATA3 pathway.
Li Q, Zhang J, Ma L, Wu C, Zhao J, Guan W, Li X, Yang X, Wen F
International immunopharmacology 2021 Dec;101(Pt B):108330
International immunopharmacology 2021 Dec;101(Pt B):108330
Bixin protects mice against bronchial asthma though modulating PI3K/Akt pathway.
Zhu Y, Sun D, Liu H, Sun L, Jie J, Luo J, Peng L, Song L
International immunopharmacology 2021 Dec;101(Pt B):108266
International immunopharmacology 2021 Dec;101(Pt B):108266
Senescence marker protein 30 (SMP30) protects against high glucose-induced apoptosis, oxidative stress and inflammatory response in retinal ganglion cells by enhancing Nrf2 activation via regulation of Akt/GSK-3β pathway.
Zhang L, Zhu T, He F, Li X
International immunopharmacology 2021 Dec;101(Pt B):108238
International immunopharmacology 2021 Dec;101(Pt B):108238
Sub-chronic exposure to realgar induces liver injury via upregulating the TXNIP/NLRP3 pathway and disturbing bile acid homeostasis in mice.
Li A, Wu X, Yang J, Li J, Guo H, Zhang Y, Jiang H, Huo T
Journal of ethnopharmacology 2021 Dec 5;281:114584
Journal of ethnopharmacology 2021 Dec 5;281:114584
Protective effect of combination of anakinra and MCC950 against acute lung injury is achieved through suppression of the NF-κB-mediated-MAPK and NLRP3-caspase pathways.
Wang X, Chen S, Zhao L, Shi X
International immunopharmacology 2021 Aug;97:107506
International immunopharmacology 2021 Aug;97:107506
Guanosine and uridine alleviate airway inflammation via inhibition of the MAPK and NF-κB signals in OVA-induced asthmatic mice.
Luo Y, Chen H, Huang R, Wu Q, Li Y, He Y
Pulmonary pharmacology & therapeutics 2021 Aug;69:102049
Pulmonary pharmacology & therapeutics 2021 Aug;69:102049
Inhibitor of apoptosis-stimulating p53 protein protects against inflammatory bowel disease in mice models by inhibiting the nuclear factor kappa B signaling.
Qian K, Yuan L, Wang S, Kuang Y, Jin Q, Long D, Jiang Y, Zhao H, Liu K, Yao H
Clinical and experimental immunology 2021 Aug;205(2):246-256
Clinical and experimental immunology 2021 Aug;205(2):246-256
CDDO-Im exerts antidepressant-like effects via the Nrf2/ARE pathway in a rat model of post-stroke depression.
Hou X, Liu H, Ping Y, Zhang F, Zhi L, Jiang X, Zhang F, Song C, Zhang Z, Song J
Brain research bulletin 2021 Aug;173:74-81
Brain research bulletin 2021 Aug;173:74-81
Yak milk-derived exosomes alleviate lipopolysaccharide-induced intestinal inflammation by inhibiting PI3K/AKT/C3 pathway activation.
Gao HN, Hu H, Wen PC, Lian S, Xie XL, Song HL, Yang ZN, Ren FZ
Journal of dairy science 2021 Aug;104(8):8411-8424
Journal of dairy science 2021 Aug;104(8):8411-8424
Celastrol exerts a neuroprotective effect by directly binding to HMGB1 protein in cerebral ischemia-reperfusion.
Liu DD, Luo P, Gu L, Zhang Q, Gao P, Zhu Y, Chen X, Guo Q, Zhang J, Ma N, Wang J
Journal of neuroinflammation 2021 Aug 9;18(1):174
Journal of neuroinflammation 2021 Aug 9;18(1):174
Ginsenoside Rg5 Improves Insulin Resistance and Mitochondrial Biogenesis of Liver via Regulation of the Sirt1/PGC-1α Signaling Pathway in db/db Mice.
Zhu Y, Yang H, Deng J, Fan D
Journal of agricultural and food chemistry 2021 Aug 4;69(30):8428-8439
Journal of agricultural and food chemistry 2021 Aug 4;69(30):8428-8439
Aiduqing formula inhibits breast cancer metastasis by suppressing TAM/CXCL1-induced Treg differentiation and infiltration.
Li J, Wang S, Wang N, Zheng Y, Yang B, Wang X, Zhang J, Pan B, Wang Z
Cell communication and signaling : CCS 2021 Aug 30;19(1):89
Cell communication and signaling : CCS 2021 Aug 30;19(1):89
Acute ischemic stroke triggers a cellular senescence-associated secretory phenotype.
Torres-Querol C, Torres P, Vidal N, Portero-Otín M, Arque G, Purroy F
Scientific reports 2021 Aug 3;11(1):15752
Scientific reports 2021 Aug 3;11(1):15752
Heteronemin Suppresses Lymphangiogenesis through ARF-1 and MMP-9/VE-Cadherin/Vimentin.
Chen HL, Su YC, Chen HC, Su JH, Wu CY, Wang SW, Lin IP, Chen CY, Lee CH
Biomedicines 2021 Aug 29;9(9)
Biomedicines 2021 Aug 29;9(9)
Glycyrrhizic Acid Alleviates Lipopolysaccharide (LPS)-Induced Acute Lung Injury by Regulating Angiotensin-Converting Enzyme-2 (ACE2) and Caveolin-1 Signaling Pathway.
Chen Y, Qu L, Li Y, Chen C, He W, Shen L, Zhang R
Inflammation 2021 Aug 24;
Inflammation 2021 Aug 24;
Tubeimoside I protects against sepsis-induced cardiac dysfunction via SIRT3.
Cheng Z, Lv D, Luo M, Wang R, Guo Y, Yang X, Huang L, Li X, Li C, Shang FF, Huang B, Shen J, Luo S, Yan J
European journal of pharmacology 2021 Aug 15;905:174186
European journal of pharmacology 2021 Aug 15;905:174186
The epigenetic regulator BRD4 is involved in cadmium-triggered inflammatory response in rat kidney.
Gong Z, Liu G, Liu W, Zou H, Song R, Zhao H, Yuan Y, Gu J, Bian J, Zhu J, Liu Z
Ecotoxicology and environmental safety 2021 Aug 13;224:112620
Ecotoxicology and environmental safety 2021 Aug 13;224:112620
Fab Fragment of Immunoglobulin Y Modulates NF-κB and MAPK Signaling through TLR4 and αVβ3 Integrin and Inhibits the Inflammatory Effect on R264.7 Macrophages.
Zhou X, Ahn DU, Xia M, Zeng Q, Li X, Cai Z
Journal of agricultural and food chemistry 2021 Aug 11;69(31):8747-8757
Journal of agricultural and food chemistry 2021 Aug 11;69(31):8747-8757
Isoorientin Attenuated the Pyroptotic Hepatocyte Damage Induced by Benzo[a]pyrene via ROS/NF-κB/NLRP3/Caspase-1 Signaling Pathway.
Li H, Yuan L, Li X, Luo Y, Zhang Z, Li J
Antioxidants (Basel, Switzerland) 2021 Aug 11;10(8)
Antioxidants (Basel, Switzerland) 2021 Aug 11;10(8)
Ophiocordyceps lanpingensis polysaccharides alleviate chronic kidney disease through MAPK/NF-κB pathway.
Zhou S, He Y, Zhang W, Xiong Y, Jiang L, Wang J, Cui X, Qu Y, Ge F
Journal of ethnopharmacology 2021 Aug 10;276:114189
Journal of ethnopharmacology 2021 Aug 10;276:114189
Wharton's Jelly Mesenchymal Stem Cell-Derived Extracellular Vesicles Reduce SARS-CoV2-Induced Inflammatory Cytokines Under High Glucose and Uremic Toxin Conditions.
Khanh VC, Fukushige M, Chang YH, Hoang NN, Yamashita T, Obata-Yasuoka M, Hamada H, Osaka M, Hiramatsu Y, Ohneda O
Stem cells and development 2021 Aug 1;30(15):758-772
Stem cells and development 2021 Aug 1;30(15):758-772
METTL3 involves the progression of osteoarthritis probably by affecting ECM degradation and regulating the inflammatory response.
Sang W, Xue S, Jiang Y, Lu H, Zhu L, Wang C, Ma J
Life sciences 2021 Aug 1;278:119528
Life sciences 2021 Aug 1;278:119528
Anti-thrombotic activity of phenolic acids obtained from Salvia miltiorrhiza f. alba in TNF-α-stimulated endothelial cells via the NF-κB/JNK/p38 MAPK signaling pathway.
Zheng X, Liu H, Ma M, Ji J, Zhu F, Sun L
Archives of pharmacal research 2021 Apr;44(4):427-438
Archives of pharmacal research 2021 Apr;44(4):427-438
African Swine Fever Virus MGF360-12L Inhibits Type I Interferon Production by Blocking the Interaction of Importin α and NF-κB Signaling Pathway.
Zhuo Y, Guo Z, Ba T, Zhang C, He L, Zeng C, Dai H
Virologica Sinica 2021 Apr;36(2):176-186
Virologica Sinica 2021 Apr;36(2):176-186
Small molecule screening identified cepharanthine as an inhibitor of porcine reproductive and respiratory syndrome virus infection in vitro by suppressing integrins/ILK/RACK1/PKCα/NF-κB signalling axis.
Yang C, Zuo Q, Liu X, Zhao Q, Pu H, Gao L, Zhao L, Guo Z, Lin Y, Liu J, Bi J, Yin G
Veterinary microbiology 2021 Apr;255:109016
Veterinary microbiology 2021 Apr;255:109016
Curcumin inhibits the growth of liver cancer by impairing myeloid-derived suppressor cells in murine tumor tissues.
Tian S, Liao L, Zhou Q, Huang X, Zheng P, Guo Y, Deng T, Tian X
Oncology letters 2021 Apr;21(4):286
Oncology letters 2021 Apr;21(4):286
Ginsenoside Rh4 alleviates antibiotic-induced intestinal inflammation by regulating the TLR4-MyD88-MAPK pathway and gut microbiota composition.
Bai X, Fu R, Duan Z, Liu Y, Zhu C, Fan D
Food & function 2021 Apr 7;12(7):2874-2885
Food & function 2021 Apr 7;12(7):2874-2885
Hydrogen Sulfide Attenuates Aortic Remodeling in Aortic Dissection Associating with Moderated Inflammation and Oxidative Stress through a NO-Dependent Pathway.
Lu HY, Hsu HL, Li CH, Li SJ, Lin SJ, Shih CM, Shih CC
Antioxidants (Basel, Switzerland) 2021 Apr 27;10(5)
Antioxidants (Basel, Switzerland) 2021 Apr 27;10(5)
Deficiency of CD147 Attenuated Non-alcoholic Steatohepatitis Progression in an NLRP3-Dependent Manner.
Zhang T, Li H, Wang K, Xu B, Chen ZN, Bian H
Frontiers in cell and developmental biology 2020;8:784
Frontiers in cell and developmental biology 2020;8:784
Blockade of Macrophage CD147 Protects Against Foam Cell Formation in Atherosclerosis.
Lv JJ, Wang H, Cui HY, Liu ZK, Zhang RY, Lu M, Li C, Yong YL, Liu M, Zhang H, Zhang TJ, Zhang K, Li G, Nan G, Zhang C, Guo SP, Wang L, Chen ZN, Bian H
Frontiers in cell and developmental biology 2020;8:609090
Frontiers in cell and developmental biology 2020;8:609090
Chronic intermittent hypoxia vs chronic continuous hypoxia: Effects on vascular endothelial function and myocardial contractility.
Zhu J, Kang J, Li X, Wang M, Shang M, Luo Y, Xiong M, Hu K
Clinical hemorheology and microcirculation 2020;74(4):417-427
Clinical hemorheology and microcirculation 2020;74(4):417-427
Bta-miR-223 Targeting CBLB Contributes to Resistance to Staphylococcus aureus Mastitis Through the PI3K/AKT/NF-κB Pathway.
Han S, Li X, Liu J, Zou Z, Luo L, Wu R, Zhao Z, Wang C, Shen B
Frontiers in veterinary science 2020;7:529
Frontiers in veterinary science 2020;7:529
Koumine Alleviates Lipopolysaccharide-Induced Intestinal Barrier Dysfunction in IPEC-J2 Cells by Regulating Nrf2/NF-
Wu J, Yang CL, Sha YK, Wu Y, Liu ZY, Yuan ZH, Sun ZL
The American journal of Chinese medicine 2020;48(1):127-142
The American journal of Chinese medicine 2020;48(1):127-142
Effects of intragastric administration of La2O3 nanoparticles on mouse testes.
Yuan L, Bai D, Meng L, Wang H, Sun Z, An T, Chen Z, Deng X, Zhang X
The Journal of toxicological sciences 2020;45(8):411-422
The Journal of toxicological sciences 2020;45(8):411-422
GNAS promotes inflammation-related hepatocellular carcinoma progression by promoting STAT3 activation.
Ding H, Zhang X, Su Y, Jia C, Dai C
Cellular & molecular biology letters 2020;25:8
Cellular & molecular biology letters 2020;25:8
Dietary Baicalin Zinc Supplementation Alleviates Oxidative Stress and Enhances Nutrition Absorption in Deoxynivalenol Challenged Pigs.
Zha A, Cui Z, Qi M, Liao S, Chen L, Liao P, Tan B
Current drug metabolism 2020;21(8):614-625
Current drug metabolism 2020;21(8):614-625
Alpha-Fetoprotein Regulates the Expression of Immune-Related Proteins through the NF-κB (P65) Pathway in Hepatocellular Carcinoma Cells.
Li QT, Qiu MJ, Yang SL, Fang X, He XX, Wang MM, Li YN, Xiong ZF, Huang S
Journal of oncology 2020;2020:9327512
Journal of oncology 2020;2020:9327512
Neuroprotective Effects of the Sonic Hedgehog Signaling Pathway in Ischemic Injury through Promotion of Synaptic and Neuronal Health.
Yin S, Bai X, Xin D, Li T, Chu X, Ke H, Han M, Chen W, Li X, Wang Z
Neural plasticity 2020;2020:8815195
Neural plasticity 2020;2020:8815195
Aloe Emodin Reduces Cardiac Inflammation Induced by a High-Fat Diet through the TLR4 Signaling Pathway.
Chen Y, Feng B, Yuan Y, Hu J, Zhao W, Jiang H, Li W, Fan Z, Du Z
Mediators of inflammation 2020;2020:6318520
Mediators of inflammation 2020;2020:6318520
The Evaluation of the Antioxidant and Intestinal Protective Effects of Baicalin-Copper in Deoxynivalenol-Challenged Piglets.
Zha A, Yuan D, Cui Z, Qi M, Liao S, Liao P, Tan B
Oxidative medicine and cellular longevity 2020;2020:5363546
Oxidative medicine and cellular longevity 2020;2020:5363546
The Class III PI3K/Beclin-1 Autophagic Pathway Participates in the mmLDL-Induced Upregulation of ETA Receptor in Mouse Mesenteric Arteries.
Xie X, Chen C, Xu CB, Lin J, Cao L, Chen G, Li J
Advances in pharmacological and pharmaceutical sciences 2020;2020:5070436
Advances in pharmacological and pharmaceutical sciences 2020;2020:5070436
Thymoquinone Protects against Hyperlipidemia-Induced Cardiac Damage in Low-Density Lipoprotein Receptor-Deficient (LDL-R-/-) Mice via Its Anti-inflammatory and Antipyroptotic Effects.
Pei ZW, Guo Y, Zhu HL, Dong M, Zhang Q, Wang F
BioMed research international 2020;2020:4878704
BioMed research international 2020;2020:4878704
The Herbal Medicine Scutellaria-Coptis Alleviates Intestinal Mucosal Barrier Damage in Diabetic Rats by Inhibiting Inflammation and Modulating the Gut Microbiota.
Zhang B, Yue R, Chen Y, Huang X, Yang M, Shui J, Peng Y
Evidence-based complementary and alternative medicine : eCAM 2020;2020:4568629
Evidence-based complementary and alternative medicine : eCAM 2020;2020:4568629
Protective Effects of Cinnamaldehyde against Mesenteric Ischemia-Reperfusion-Induced Lung and Liver Injuries in Rats.
Almoiliqy M, Wen J, Qaed E, Sun Y, Lian M, Mousa H, Al-Azab M, Zaky MY, Chen D, Wang L, Al-Sharabi A, Liu Z, Sun P, Lin Y
Oxidative medicine and cellular longevity 2020;2020:4196548
Oxidative medicine and cellular longevity 2020;2020:4196548
Anti-Inflammatory and Antioxidant Effect of Eucommia ulmoides Polysaccharide in Hepatic Ischemia-Reperfusion Injury by Regulating ROS and the TLR-4-NF-κB Pathway.
Gao W, Feng Z, Zhang S, Wu B, Geng X, Fan G, Duan Y, Li K, Liu K, Peng C
BioMed research international 2020;2020:1860637
BioMed research international 2020;2020:1860637
Effect of Thymoquinone on Acute Kidney Injury Induced by Sepsis in BALB/c Mice.
Guo LP, Liu SX, Yang Q, Liu HY, Xu LL, Hao YH, Zhang XQ
BioMed research international 2020;2020:1594726
BioMed research international 2020;2020:1594726
PRMT6 mediates inflammation via activation of the NF-κB/p65 pathway on a cigarette smoke extract-induced murine emphysema model.
He X, Li T, Luo L, Zeng H, Chen Y, Cai S
Tobacco induced diseases 2020;18:8
Tobacco induced diseases 2020;18:8
Ozone Therapy Attenuates NF-κB-Mediated Local Inflammatory Response and Activation of Th17 Cells in Treatment for Psoriasis.
Zeng J, Lei L, Zeng Q, Yao Y, Wu Y, Li Q, Gao L, Du H, Xie Y, Huang J, Tan W, Lu J
International journal of biological sciences 2020;16(11):1833-1845
International journal of biological sciences 2020;16(11):1833-1845
Sevoflurane-Induced Neuroapoptosis in Rat Dentate Gyrus Is Activated by Autophagy Through NF-κB Signaling on the Late-Stage Progenitor Granule Cells.
Tong D, Ma Z, Su P, Wang S, Xu Y, Zhang LM, Wu Z, Liu K, Zhao P
Frontiers in cellular neuroscience 2020;14:590577
Frontiers in cellular neuroscience 2020;14:590577
Emodin Protects Against Acute Pancreatitis-Associated Lung Injury by Inhibiting NLPR3 Inflammasome Activation via Nrf2/HO-1 Signaling.
Gao Z, Sui J, Fan R, Qu W, Dong X, Sun D
Drug design, development and therapy 2020;14:1971-1982
Drug design, development and therapy 2020;14:1971-1982
Salvianolic Acid B Improves Chronic Mild Stress-Induced Depressive Behaviors in Rats: Involvement of AMPK/SIRT1 Signaling Pathway.
Liao D, Chen Y, Guo Y, Wang C, Liu N, Gong Q, Fu Y, Fu Y, Cao L, Yao D, Jiang P
Journal of inflammation research 2020;13:195-206
Journal of inflammation research 2020;13:195-206
β-catenin regulates myocardial ischemia/reperfusion injury following heterotopic heart transplantation in mice by modulating PTEN pathways.
Ban Q, Qiao L, Xia H, Xie B, Liu J, Ma Y, Zhang L, Zhang M, Liu LG, Jiao W, Yang S, Li Z, Zheng S, Liu D, Xia J, Qi Z
American journal of translational research 2020;12(8):4757-4771
American journal of translational research 2020;12(8):4757-4771
The LINC00365/SCGB2A1 (Mammaglobin B) Axis Down-Regulates NF-κB Signaling and Is Associated with the Progression of Gastric Cancer.
Yan XY, Zhang JJ, Zhong XR, Yu SH, Xu L, Tian R, Sun LK, Su J
Cancer management and research 2020;12:621-631
Cancer management and research 2020;12:621-631
Dl-3-n-Butylphthalide Promotes Remyelination and Suppresses Inflammation by Regulating AMPK/SIRT1 and STAT3/NF-κB Signaling in Chronic Cerebral Hypoperfusion.
Li M, Meng N, Guo X, Niu X, Zhao Z, Wang W, Xie X, Lv P
Frontiers in aging neuroscience 2020;12:137
Frontiers in aging neuroscience 2020;12:137
Resatorvid Relieves Breast Cancer Complicated with Depression by Inactivating Hippocampal Microglia Through TLR4/NF-κB/NLRP3 Signaling Pathway.
Luo W, Han Y, Meng P, Yang Q, Zhao H, Ling J, Wang Y
Cancer management and research 2020;12:13003-13014
Cancer management and research 2020;12:13003-13014
Hyperoside Protects Human Umbilical Vein Endothelial Cells Against Anticardiolipin Antibody-Induced Injury by Activating Autophagy.
Wei A, Xiao H, Xu G, Yu X, Guo J, Jing Z, Shi S, Song Y
Frontiers in pharmacology 2020;11:762
Frontiers in pharmacology 2020;11:762
Inhibitory Effects of the Lactobacillus rhamnosus GG Effector Protein HM0539 on Inflammatory Response Through the TLR4/MyD88/NF-кB Axis.
Li Y, Yang S, Lun J, Gao J, Gao X, Gong Z, Wan Y, He X, Cao H
Frontiers in immunology 2020;11:551449
Frontiers in immunology 2020;11:551449
Herpes Simplex Virus 1 UL2 Inhibits the TNF-α-Mediated NF-κB Activity by Interacting With p65/p50.
Cai M, Liao Z, Zou X, Xu Z, Wang Y, Li T, Li Y, Ou X, Deng Y, Guo Y, Peng T, Li M
Frontiers in immunology 2020;11:549
Frontiers in immunology 2020;11:549
Aucubin Attenuates Liver Ischemia-Reperfusion Injury by Inhibiting the HMGB1/TLR-4/NF-κB Signaling Pathway, Oxidative Stress, and Apoptosis.
Zhang S, Feng Z, Gao W, Duan Y, Fan G, Geng X, Wu B, Li K, Liu K, Peng C
Frontiers in pharmacology 2020;11:544124
Frontiers in pharmacology 2020;11:544124
Sodium Butyrate Abrogates the Growth and Pathogenesis of Mycobacterium bovis via Regulation of Cathelicidin (LL37) Expression and NF-κB Signaling.
Zhang K, Hussain T, Wang J, Li M, Wang W, Ma X, Liao Y, Yao J, Song Y, Liang Z, Zhou X, Xu L
Frontiers in microbiology 2020;11:433
Frontiers in microbiology 2020;11:433
Mycoplasma genitalium Protein of Adhesion Induces Inflammatory Cytokines via Cyclophilin A-CD147 Activating the ERK-NF-κB Pathway in Human Urothelial Cells.
Li L, Luo D, Liao Y, Peng K, Zeng Y
Frontiers in immunology 2020;11:2052
Frontiers in immunology 2020;11:2052
Serine Supports IL-1β Production in Macrophages Through mTOR Signaling.
Chen S, Xia Y, He F, Fu J, Xin Z, Deng B, He L, Zhou X, Ren W
Frontiers in immunology 2020;11:1866
Frontiers in immunology 2020;11:1866
Selenomethionine Suppressed TLR4/NF-κB Pathway by Activating Selenoprotein S to Alleviate ESBL Escherichia coli-Induced Inflammation in Bovine Mammary Epithelial Cells and Macrophages.
Zhuang C, Liu G, Barkema HW, Zhou M, Xu S, Ur Rahman S, Liu Y, Kastelic JP, Gao J, Han B
Frontiers in microbiology 2020;11:1461
Frontiers in microbiology 2020;11:1461
Sevoflurane Protects against Intestinal Ischemia-Reperfusion Injury by Activating Peroxisome Proliferator-Activated Receptor Gamma/Nuclear Factor-κB Pathway in Rats.
Liu C, Ding R, Huang W, Miao L, Li J, Li Y
Pharmacology 2020;105(3-4):231-242
Pharmacology 2020;105(3-4):231-242
GFPT2 promotes metastasis and forms a positive feedback loop with p65 in colorectal cancer.
Liu L, Pan Y, Ren X, Zeng Z, Sun J, Zhou K, Liang Y, Wang F, Yan Y, Liao W, Ding Y, Liu X, Liang L
American journal of cancer research 2020;10(8):2510-2522
American journal of cancer research 2020;10(8):2510-2522
Genetic and pharmacological activation of Hedgehog signaling inhibits osteoclastogenesis and attenuates titanium particle-induced osteolysis partly through suppressing the JNK/c-Fos-NFATc1 cascade.
Zhang L, Yang Y, Liao Z, Liu Q, Lei X, Li M, Saijilafu, Zhang Z, Hong D, Zhu M, Li B, Yang H, Chen J
Theranostics 2020;10(15):6638-6660
Theranostics 2020;10(15):6638-6660
Dynorphin activation of kappa opioid receptor promotes microglial polarization toward M2 phenotype via TLR4/NF-κB pathway.
Liu L, Xu Y, Dai H, Tan S, Mao X, Chen Z
Cell & bioscience 2020;10:42
Cell & bioscience 2020;10:42
Geraniol-mediated osteoarthritis improvement by down-regulating PI3K/Akt/NF-κB and MAPK signals: In vivo and in vitro studies.
Wu Y, Wang Z, Fu X, Lin Z, Yu K
International immunopharmacology 2020 Sep;86:106713
International immunopharmacology 2020 Sep;86:106713
CEACAM1 Inhibited IκB-α/NF-κB Signal Pathway Via Targeting MMP-9/TIMP-1 Axis in Diabetic Atherosclerosis.
Yu J, Sun G, Chen Y, Li L, Wang H, Tu D, Li L, Meng Z, Wang Y
Journal of cardiovascular pharmacology 2020 Sep;76(3):329-336
Journal of cardiovascular pharmacology 2020 Sep;76(3):329-336
Cetuximab enhances oridonin-induced apoptosis through mitochondrial pathway and endoplasmic reticulum stress in laryngeal squamous cell carcinoma cells.
Kang N, Cao S, Jiang B, Zhang Q, Donkor PO, Zhu Y, Qiu F, Gao X
Toxicology in vitro : an international journal published in association with BIBRA 2020 Sep;67:104885
Toxicology in vitro : an international journal published in association with BIBRA 2020 Sep;67:104885
Cinnamaldehyde protects against rat intestinal ischemia/reperfusion injuries by synergistic inhibition of NF-κB and p53.
Almoiliqy M, Wen J, Xu B, Sun YC, Lian MQ, Li YL, Qaed E, Al-Azab M, Chen DP, Shopit A, Wang L, Sun PY, Lin Y
Acta pharmacologica Sinica 2020 Sep;41(9):1208-1222
Acta pharmacologica Sinica 2020 Sep;41(9):1208-1222
The effect of monotropein on alleviating cisplatin-induced acute kidney injury by inhibiting oxidative damage, inflammation and apoptosis.
Zhang Y, Chen Y, Li B, Ding P, Jin D, Hou S, Cai X, Sheng X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Sep;129:110408
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Sep;129:110408
Staphylococcal enterotoxin M induced inflammation and impairment of bovine mammary epithelial cells.
Zhao Y, Tang J, Yang D, Tang C, Chen J
Journal of dairy science 2020 Sep;103(9):8350-8359
Journal of dairy science 2020 Sep;103(9):8350-8359
Monotropein alleviates secondary liver injury in chronic colitis by regulating TLR4/NF-κB signaling and NLRP3 inflammasome.
Chen Y, Lu Y, Pei C, Liang J, Ding P, Chen S, Hou SZ
European journal of pharmacology 2020 Sep 15;883:173358
European journal of pharmacology 2020 Sep 15;883:173358
Copper induces oxidative stress with triggered NF-κB pathway leading to inflammatory responses in immune organs of chicken.
Yang F, Liao J, Yu W, Pei R, Qiao N, Han Q, Hu L, Li Y, Guo J, Pan J, Tang Z
Ecotoxicology and environmental safety 2020 Sep 1;200:110715
Ecotoxicology and environmental safety 2020 Sep 1;200:110715
LncRNA AY343892 inhibits breast cancer development by positively regulating BRCA1-mediated transcription of PTEN.
Li Y, Zhang M, Li F
Histology and histopathology 2020 Oct;35(10):1171-1180
Histology and histopathology 2020 Oct;35(10):1171-1180
TLR4 contributes to the damage of cartilage and subchondral bone in discectomy-induced TMJOA mice.
Liu X, Cai HX, Cao PY, Feng Y, Jiang HH, Liu L, Ke J, Long X
Journal of cellular and molecular medicine 2020 Oct;24(19):11489-11499
Journal of cellular and molecular medicine 2020 Oct;24(19):11489-11499
Potential hazardous effects of printing room PM2.5 exposure include promotion of lung inflammation and subsequent injury.
Zou C, Yang H, Cui L, Cao X, Huang H, Chen T
Molecular medicine reports 2020 Oct;22(4):3213-3224
Molecular medicine reports 2020 Oct;22(4):3213-3224
(-)-Hydroxycitric Acid Alleviates Oleic Acid-Induced Steatosis, Oxidative Stress, and Inflammation in Primary Chicken Hepatocytes by Regulating AMP-Activated Protein Kinase-Mediated Reactive Oxygen Species Levels.
Li L, Chu X, Yao Y, Cao J, Li Q, Ma H
Journal of agricultural and food chemistry 2020 Oct 7;68(40):11229-11241
Journal of agricultural and food chemistry 2020 Oct 7;68(40):11229-11241
Ketogenic Diet Elicits Antitumor Properties through Inducing Oxidative Stress, Inhibiting MMP-9 Expression, and Rebalancing M1/M2 Tumor-Associated Macrophage Phenotype in a Mouse Model of Colon Cancer.
Zhang N, Liu C, Jin L, Zhang R, Wang T, Wang Q, Chen J, Yang F, Siebert HC, Zheng X
Journal of agricultural and food chemistry 2020 Oct 7;68(40):11182-11196
Journal of agricultural and food chemistry 2020 Oct 7;68(40):11182-11196
CP-25 improves nephropathy in collagen-induced arthritis rats by inhibiting the renal inflammatory response.
Wang C, Wei X, Wu Y, Tang H, Wang B, Wang Y, Sun W, Asenso J, Xiao F, Wei W
International immunopharmacology 2020 Nov;88:106997
International immunopharmacology 2020 Nov;88:106997
microRNA-421-3p prevents inflammatory response in cerebral ischemia/reperfusion injury through targeting m6A Reader YTHDF1 to inhibit p65 mRNA translation.
Zheng L, Tang X, Lu M, Sun S, Xie S, Cai J, Zan J
International immunopharmacology 2020 Nov;88:106937
International immunopharmacology 2020 Nov;88:106937
PDLIM2 protects articular chondrocytes from lipopolysaccharide-induced apoptosis, degeneration and inflammatory injury through down-regulation of nuclear factor (NF)-κB signaling.
Guo Q, Xu J, Shi Q, Wu S
International immunopharmacology 2020 Nov;88:106883
International immunopharmacology 2020 Nov;88:106883
Panax notoginseng saponin R1 modulates TNF-α/NF-κB signaling and attenuates allergic airway inflammation in asthma.
Xue K, Ruan L, Hu J, Fu Z, Tian D, Zou W
International immunopharmacology 2020 Nov;88:106860
International immunopharmacology 2020 Nov;88:106860
Proteases Activate Pregnancy Neutrophils by a Protease-Activated Receptor 1 Pathway: Epigenetic Implications for Preeclampsia.
Walsh SW, Nugent WH, Al Dulaimi M, Washington SL, Dacha P, Strauss JF 3rd
Reproductive sciences (Thousand Oaks, Calif.) 2020 Nov;27(11):2115-2127
Reproductive sciences (Thousand Oaks, Calif.) 2020 Nov;27(11):2115-2127
Role of TLR4/MyD88/NF-κB signaling in the contrast-induced injury of renal tubular epithelial cells.
Wang X, Zhou J, Yang J, Wang S, Yang L
Experimental and therapeutic medicine 2020 Nov;20(5):115
Experimental and therapeutic medicine 2020 Nov;20(5):115
Protective effect of astaxanthin against SnS2 nanoflowers induced testes toxicity by suppressing RIPK1-RIPK3-MLKL signaling in mice.
Yuan L, Liang P, Qu Y, An T, Wang J, Deng X, Bai L, Shen P, Bai D
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2020 Nov;145:111736
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2020 Nov;145:111736
The anti-inflammatory potential of protein-bound anthocyanin compounds from purple sweet potato in LPS-induced RAW264.7 macrophages.
Jiang T, Zhou J, Liu W, Tao W, He J, Jin W, Guo H, Yang N, Li Y
Food research international (Ottawa, Ont.) 2020 Nov;137:109647
Food research international (Ottawa, Ont.) 2020 Nov;137:109647
Crocin ameliorates arsenic trioxide‑induced cardiotoxicity via Keap1-Nrf2/HO-1 pathway: Reducing oxidative stress, inflammation, and apoptosis.
Liang Y, Zheng B, Li J, Shi J, Chu L, Han X, Chu X, Zhang X, Zhang J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Nov;131:110713
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Nov;131:110713
Acetylharpagide Protects Mice from Staphylococcus Aureus-Induced Acute Lung Injury by Inhibiting NF-κB Signaling Pathway.
Zhang Z, Wang Y, Shan Y, Yin W
Molecules (Basel, Switzerland) 2020 Nov 25;25(23)
Molecules (Basel, Switzerland) 2020 Nov 25;25(23)
Inhibition of notch enhances the anti-atherosclerotic effects of LXR agonists while reducing fatty liver development in ApoE-deficient mice.
Hao Y, Wang X, Zhang F, Wang M, Wang Y, Wang H, Du Y, Wang T, Fu F, Gao Z, Zhang L
Toxicology and applied pharmacology 2020 Nov 1;406:115211
Toxicology and applied pharmacology 2020 Nov 1;406:115211
ADAM12 silencing promotes cellular apoptosis by activating autophagy in choriocarcinoma cells.
Wang L, Tan Z, Zhang Y, Kady Keita N, Liu H, Zhang Y
International journal of oncology 2020 May;56(5):1162-1174
International journal of oncology 2020 May;56(5):1162-1174
Pin1 promotes pancreatic cancer progression and metastasis by activation of NF-κB-IL-18 feedback loop.
Sun Q, Fan G, Zhuo Q, Dai W, Ye Z, Ji S, Xu W, Liu W, Hu Q, Zhang Z, Liu M, Yu X, Xu X, Qin Y
Cell proliferation 2020 May;53(5):e12816
Cell proliferation 2020 May;53(5):e12816
Annexin-1 Mimetic Peptide Ac2-26 Suppresses Inflammatory Mediators in LPS-Induced Astrocytes and Ameliorates Pain Hypersensitivity in a Rat Model of Inflammatory Pain.
Luo Z, Wang H, Fang S, Li L, Li X, Shi J, Zhu M, Tan Z, Lu Z
Cellular and molecular neurobiology 2020 May;40(4):569-585
Cellular and molecular neurobiology 2020 May;40(4):569-585
Porcine parvovirus nonstructural protein NS1 activates NF-κB and it involves TLR2 signaling pathway.
Jin X, Yuan Y, Zhang C, Zhou Y, Song Y, Wei Z, Zhang G
Journal of veterinary science 2020 May;21(3):e50
Journal of veterinary science 2020 May;21(3):e50
Protective effect of ginsenoside Rg5 against kidney injury via inhibition of NLRP3 inflammasome activation and the MAPK signaling pathway in high-fat diet/streptozotocin-induced diabetic mice.
Zhu Y, Zhu C, Yang H, Deng J, Fan D
Pharmacological research 2020 May;155:104746
Pharmacological research 2020 May;155:104746
Ruscogenin alleviates LPS-induced pulmonary endothelial cell apoptosis by suppressing TLR4 signaling.
Wu Y, Wang Y, Gong S, Tang J, Zhang J, Li F, Yu B, Zhang Y, Kou J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109868
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109868
Hic-5 deficiency attenuates hepatic ischemia reperfusion injury through TLR4/NF-κB signaling pathways.
Gao L, Qian B, Chen H, Wang A, Li Q, Li J, Tan P, Xia X, Du Y, Fu W
Life sciences 2020 May 15;249:117517
Life sciences 2020 May 15;249:117517
Time serial transcriptome reveals Cyp2c29 as a key gene in hepatocellular carcinoma development.
Wang Q, Tang Q, Zhao L, Zhang Q, Wu Y, Hu H, Liu L, Liu X, Zhu Y, Guo A, Yang X
Cancer biology & medicine 2020 May 15;17(2):401-417
Cancer biology & medicine 2020 May 15;17(2):401-417
Inhibition of the NLRP3-inflammasome prevents cognitive deficits in experimental autoimmune encephalomyelitis mice via the alteration of astrocyte phenotype.
Hou B, Zhang Y, Liang P, He Y, Peng B, Liu W, Han S, Yin J, He X
Cell death & disease 2020 May 15;11(5):377
Cell death & disease 2020 May 15;11(5):377
Androgen aggravates liver fibrosis by activation of NLRP3 inflammasome in CCl4-induced liver injury mouse model.
Ma X, Zhou Y, Qiao B, Jiang S, Shen Q, Han Y, Liu A, Chen X, Wei L, Zhou L, Zhao J
American journal of physiology. Endocrinology and metabolism 2020 May 1;318(5):E817-E829
American journal of physiology. Endocrinology and metabolism 2020 May 1;318(5):E817-E829
Ketamine attenuates high-glucose-mediated endothelial inflammation in human umbilical vein endothelial cells.
Wang T, Zhu H, Hou Y, Duan W, Meng F, Liu Y
Canadian journal of physiology and pharmacology 2020 Mar;98(3):156-161
Canadian journal of physiology and pharmacology 2020 Mar;98(3):156-161
Pyrroloquinoline quinone attenuates isoproterenol hydrochloride‑induced cardiac hypertrophy in AC16 cells by inhibiting the NF‑κB signaling pathway.
Wen J, Shen J, Zhou Y, Zhao X, Dai Z, Jin Y
International journal of molecular medicine 2020 Mar;45(3):873-885
International journal of molecular medicine 2020 Mar;45(3):873-885
Treatment with a probiotic combination reduces abdominal adhesion in rats by decreasing intestinal inflammation and restoring microbial composition.
Deng X, Zheng C, Wang S, Yang R, Liu Z, Chen T
Oncology reports 2020 Mar;43(3):986-998
Oncology reports 2020 Mar;43(3):986-998
Influence of feature rankers in the construction of molecular activity prediction models.
Cerruela-García G, Pérez-Parra Toledano J, de Haro-García A, García-Pedrajas N
Journal of computer-aided molecular design 2020 Mar;34(3):305-325
Journal of computer-aided molecular design 2020 Mar;34(3):305-325
Oxymatrine suppresses IL-1β-induced degradation of the nucleus pulposus cell and extracellular matrix through the TLR4/NF-κB signaling pathway.
Wei K, Dai J, Wang Z, Pei Y, Chen Y, Ding Y, Ding Q, Ahati P, Zhou X, Wang H, Fang H
Experimental biology and medicine (Maywood, N.J.) 2020 Mar;245(6):532-541
Experimental biology and medicine (Maywood, N.J.) 2020 Mar;245(6):532-541
Ubiquitination of P53 by E3 ligase MKRN2 promotes melanoma cell proliferation.
Zhang Y, Cui N, Zheng G
Oncology letters 2020 Mar;19(3):1975-1984
Oncology letters 2020 Mar;19(3):1975-1984
The Immunomodulatory Effects and Mechanisms of Tim-3 Action in the Early Stage of Mice with Severe Acute Pancreatitis.
Lin M, Huang J, Chen WC, Fan ZN, Qin X
Iranian journal of immunology : IJI 2020 Mar;17(1):52-63
Iranian journal of immunology : IJI 2020 Mar;17(1):52-63
RNF90 negatively regulates cellular antiviral responses by targeting MITA for degradation.
Yang B, Liu Y, Cui Y, Song D, Zhang G, Ma S, Liu Y, Chen M, Chen F, Wang H, Wang J
PLoS pathogens 2020 Mar;16(3):e1008387
PLoS pathogens 2020 Mar;16(3):e1008387
IFI16 promotes cervical cancer progression by upregulating PD-L1 in immunomicroenvironment through STING-TBK1-NF-kB pathway.
Cai H, Yan L, Liu N, Xu M, Cai H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Mar;123:109790
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Mar;123:109790
Far-infrared radiation prevents decline in β-cell mass and function in diabetic mice via the mitochondria-mediated Sirtuin1 pathway.
Hsu YH, Chen YC, Chen YW, Chiu TH, Kuo YT, Chen CH
Metabolism: clinical and experimental 2020 Mar;104:154143
Metabolism: clinical and experimental 2020 Mar;104:154143
Wnt5a-induced M2 polarization of tumor-associated macrophages via IL-10 promotes colorectal cancer progression.
Liu Q, Yang C, Wang S, Shi D, Wei C, Song J, Lin X, Dou R, Bai J, Xiang Z, Huang S, Liu K, Xiong B
Cell communication and signaling : CCS 2020 Mar 30;18(1):51
Cell communication and signaling : CCS 2020 Mar 30;18(1):51
Dendrobium officinale polysaccharides protected against ethanol-induced acute liver injury in vivo and in vitro via the TLR4/NF-κB signaling pathway.
Yang K, Zhan L, Lu T, Zhou C, Chen X, Dong Y, Lv G, Chen S
Cytokine 2020 Mar 26;130:155058
Cytokine 2020 Mar 26;130:155058
The protective effect of hesperetin in osteoarthritis: an in vitro and in vivo study.
Lin Z, Fu C, Yan Z, Wu Y, Zhan J, Lou Z, Liao X, Pan J
Food & function 2020 Mar 26;11(3):2654-2666
Food & function 2020 Mar 26;11(3):2654-2666
Monocyte-derived extracellular vesicles upon treated by palmitate promote endothelial migration and monocytes attachment to endothelial cells.
Gao W, Guo X, Wang Y, Jian D, Li M
Biochemical and biophysical research communications 2020 Mar 12;523(3):685-691
Biochemical and biophysical research communications 2020 Mar 12;523(3):685-691
Suppression of high-mobility group box 1 ameliorates xerostomia in a Sjögren syndrome-triggered mouse model.
Wang D, Zhou M, Wang Y, Sun S
Canadian journal of physiology and pharmacology 2020 Jun;98(6):351-356
Canadian journal of physiology and pharmacology 2020 Jun;98(6):351-356
Tle1 attenuates hepatic ischemia/reperfusion injury by suppressing NOD2/NF-κB signaling.
Chen W, Zheng D, Mou T, Pu J, Dai J, Huang Z, Luo Y, Zhang Y, Wu Z
Bioscience, biotechnology, and biochemistry 2020 Jun;84(6):1176-1182
Bioscience, biotechnology, and biochemistry 2020 Jun;84(6):1176-1182
Jmjd3 is involved in the susceptibility to depression induced by maternal separation via enhancing the neuroinflammation in the prefrontal cortex and hippocampus of male rats.
Wang R, Wang W, Xu J, Liu D, Wu H, Qin X, Jiang H, Pan F
Experimental neurology 2020 Jun;328:113254
Experimental neurology 2020 Jun;328:113254
Integrin β3, a RACK1 interacting protein, is critical for porcine reproductive and respiratory syndrome virus infection and NF-κB activation in Marc-145 cells.
Yang C, Lan R, Wang X, Zhao Q, Li X, Bi J, Wang J, Yang G, Lin Y, Liu J, Yin G
Virus research 2020 Jun;282:197956
Virus research 2020 Jun;282:197956
Evaluation of the post-treatment anti-inflammatory capacity of osteoarthritic chondrocytes: An in vitro study using baicalein.
Wu CC, Chen YR, Lu DH, Hsu LH, Yang KC, Sumi S
Regenerative therapy 2020 Jun;14:177-183
Regenerative therapy 2020 Jun;14:177-183
Tubeimoside I improves survival of mice in sepsis by inhibiting inducible nitric oxide synthase expression.
Luo M, Luo S, Cheng Z, Yang X, Lv D, Li X, Guo Y, Li C, Yan J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jun;126:110083
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jun;126:110083
Tannic acid ameliorates arsenic trioxide-induced nephrotoxicity, contribution of NF-κB and Nrf2 pathways.
Jin W, Xue Y, Xue Y, Han X, Song Q, Zhang J, Li Z, Cheng J, Guan S, Sun S, Chu L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jun;126:110047
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jun;126:110047
MGP Promotes Colon Cancer Proliferation by Activating the NF-κB Pathway through Upregulation of the Calcium Signaling Pathway.
Li X, Wei R, Wang M, Ma L, Zhang Z, Chen L, Guo Q, Guo S, Zhu S, Zhang S, Min L
Molecular therapy oncolytics 2020 Jun 26;17:371-383
Molecular therapy oncolytics 2020 Jun 26;17:371-383
Endosulfan induces endothelial inflammation and dysfunction via IRE1α/NF-κB signaling pathway.
Sun S, Ji Z, Fu J, Wang XF, Zhang LS
Environmental science and pollution research international 2020 Jul;27(21):26163-26171
Environmental science and pollution research international 2020 Jul;27(21):26163-26171
Porcine RACK1 negatively regulates the infection of classical swine fever virus and the NF-κB activation in PK-15 cells.
Wang X, Gao L, Yang X, Zuo Q, Lan R, Li M, Yang C, Lin Y, Liu J, Yin G
Veterinary microbiology 2020 Jul;246:108711
Veterinary microbiology 2020 Jul;246:108711
Maternal Exposure to Di-n-butyl Phthalate Promotes the Formation of Testicular Tight Junctions through Downregulation of NF-κB/COX-2/PGE2/MMP-2 in Mouse Offspring.
Ma T, Zhou Y, Xia Y, Meng X, Jin H, Wang B, Chen Y, Qiu J, Wu J, Ding J, Han X, Li D
Environmental science & technology 2020 Jul 7;54(13):8245-8258
Environmental science & technology 2020 Jul 7;54(13):8245-8258
The gut microbial metabolite trimethylamine N-oxide aggravates GVHD by inducing M1 macrophage polarization in mice.
Wu K, Yuan Y, Yu H, Dai X, Wang S, Sun Z, Wang F, Fei H, Lin Q, Jiang H, Chen T
Blood 2020 Jul 23;136(4):501-515
Blood 2020 Jul 23;136(4):501-515
Normothermic Machine Perfusion Combined with Bone Marrow Mesenchymal Stem Cells Improves the Oxidative Stress Response and Mitochondrial Function in Rat Donation After Circulatory Death Livers.
Yang L, Cao H, Sun D, Lin L, Zheng WP, Shen ZY, Song HL
Stem cells and development 2020 Jul 1;29(13):835-852
Stem cells and development 2020 Jul 1;29(13):835-852
Karyopherin α 2 promotes proliferation, migration and invasion through activating NF-κB/p65 signaling pathways in melanoma cells.
Yang F, Li S, Cheng Y, Li J, Han X
Life sciences 2020 Jul 1;252:117611
Life sciences 2020 Jul 1;252:117611
Retinoic acid attenuates cardiac injury induced by hyperglycemia in pre- and post-delivery mice.
Liu Y, Zhao J, Lu M, Wang H, Tang F
Canadian journal of physiology and pharmacology 2020 Jan;98(1):6-14
Canadian journal of physiology and pharmacology 2020 Jan;98(1):6-14
Plumbagin attenuated oxygen-glucose deprivation/reoxygenation-induced injury in human SH-SY5Y cells by inhibiting NOX4-derived ROS-activated NLRP3 inflammasome.
Zhang Q, Zhao S, Zheng W, Fu H, Wu T, Hu F
Bioscience, biotechnology, and biochemistry 2020 Jan;84(1):134-142
Bioscience, biotechnology, and biochemistry 2020 Jan;84(1):134-142
The m6A methyltransferase METTL3 cooperates with demethylase ALKBH5 to regulate osteogenic differentiation through NF-κB signaling.
Yu J, Shen L, Liu Y, Ming H, Zhu X, Chu M, Lin J
Molecular and cellular biochemistry 2020 Jan;463(1-2):203-210
Molecular and cellular biochemistry 2020 Jan;463(1-2):203-210
Crocin attenuates isoprenaline-induced myocardial fibrosis by targeting TLR4/NF-κB signaling: connecting oxidative stress, inflammation, and apoptosis.
Jin W, Zhang Y, Xue Y, Han X, Zhang X, Ma Z, Sun S, Chu X, Cheng J, Guan S, Li Z, Chu L
Naunyn-Schmiedeberg's archives of pharmacology 2020 Jan;393(1):13-23
Naunyn-Schmiedeberg's archives of pharmacology 2020 Jan;393(1):13-23
MiR-22 restrains proliferation of rheumatoid arthritis by targeting IL6R and may be concerned with the suppression of NF-κB pathway.
Yang QY, Yang KP, Li ZZ
The Kaohsiung journal of medical sciences 2020 Jan;36(1):20-26
The Kaohsiung journal of medical sciences 2020 Jan;36(1):20-26
Protease Amplification of the Inflammatory Response Induced by Commensal Bacteria: Implications for Racial Disparity in Term and Preterm Birth.
Walsh SW, Nugent WH, Alam SMK, Washington SL, Teves M, Jefferson KK, Strauss JF 3rd
Reproductive sciences (Thousand Oaks, Calif.) 2020 Jan;27(1):246-259
Reproductive sciences (Thousand Oaks, Calif.) 2020 Jan;27(1):246-259
MiR-146a down-regulates inflammatory response by targeting TLR3 and TRAF6 in Coxsackievirus B infection.
Fei Y, Chaulagain A, Wang T, Chen Y, Liu J, Yi M, Wang Y, Huang Y, Lin L, Chen S, Xu W, Tong L, Wu X, Zhao D, Zhang F, Zhao W, Zhong Z
RNA (New York, N.Y.) 2020 Jan;26(1):91-100
RNA (New York, N.Y.) 2020 Jan;26(1):91-100
Hic-5 deficiency protects cerulein-induced chronic pancreatitis via down-regulation of the NF-κB (p65)/IL-6 signalling pathway.
Chen H, Tan P, Qian B, Du Y, Wang A, Shi H, Huang Z, Huang S, Liang T, Fu W
Journal of cellular and molecular medicine 2020 Jan;24(2):1488-1503
Journal of cellular and molecular medicine 2020 Jan;24(2):1488-1503
Antidepressant activity of ω-3 polyunsaturated fatty acids in ovariectomized rats: role of neuroinflammation and microglial polarization.
Wu B, Song Q, Zhang Y, Wang C, Yang M, Zhang J, Han W, Jiang P
Lipids in health and disease 2020 Jan 8;19(1):4
Lipids in health and disease 2020 Jan 8;19(1):4
Dopamine attenuates lipopolysaccharide-induced expression of proinflammatory cytokines by inhibiting the nuclear translocation of NF-κB p65 through the formation of dopamine quinone in microglia.
Yoshioka Y, Sugino Y, Shibagaki F, Yamamuro A, Ishimaru Y, Maeda S
European journal of pharmacology 2020 Jan 5;866:172826
European journal of pharmacology 2020 Jan 5;866:172826
The Interleukin-33/ST2 axis promotes glioma mesenchymal transition, stemness and TMZ resistance via JNK activation.
Lin L, Li Y, Liu M, Li Q, Liu Q, Li R
Aging 2020 Jan 29;12(2):1685-1703
Aging 2020 Jan 29;12(2):1685-1703
Ginsenoside Rk1 induces apoptosis and downregulates the expression of PD-L1 by targeting the NF-κB pathway in lung adenocarcinoma.
Hu M, Yang J, Qu L, Deng X, Duan Z, Fu R, Liang L, Fan D
Food & function 2020 Jan 29;11(1):456-471
Food & function 2020 Jan 29;11(1):456-471
The potential of Diosgenin in treating psoriasis: Studies from HaCaT keratinocytes and imiquimod-induced murine model.
Wu S, Zhao M, Sun Y, Xie M, Le K, Xu M, Huang C
Life sciences 2020 Jan 15;241:117115
Life sciences 2020 Jan 15;241:117115
Dietary pterostilbene supplementation attenuates intestinal damage and immunological stress of broiler chickens challenged with lipopolysaccharide.
Zhang H, Chen Y, Chen Y, Li Y, Jia P, Ji S, Zhou Y, Wang T
Journal of animal science 2020 Jan 1;98(1)
Journal of animal science 2020 Jan 1;98(1)
Neuroinflammation induced by secretion of acetylated HMGB1 from activated microglia in hippocampi of mice following chronic cold exposure.
Xu B, Lang LM, Lian S, Guo JR, Wang JF, Liu J, Yang HM, Li SZ
Brain research 2020 Jan 1;1726:146495
Brain research 2020 Jan 1;1726:146495
Baicalein attenuates the neuroinflammation in LPS-activated BV-2 microglial cells through suppression of pro-inflammatory cytokines, COX2/NF-κB expressions and regulation of metabolic abnormality.
Yan JJ, Du GH, Qin XM, Gao L
International immunopharmacology 2020 Feb;79:106092
International immunopharmacology 2020 Feb;79:106092
Lactobacillus johnsonii L531 ameliorates enteritis via elimination of damaged mitochondria and suppression of SQSTM1-dependent mitophagy in a Salmonella infantis model of piglet diarrhea.
Xia B, Yu J, He T, Liu X, Su J, Wang M, Wang J, Zhu Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Feb;34(2):2821-2839
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Feb;34(2):2821-2839
Polyphyllin VII induces apoptotic cell death via inhibition of the PI3K/Akt and NF‑κB pathways in A549 human lung cancer cells.
He H, Xu C, Zheng L, Wang K, Jin M, Sun Y, Yue Z
Molecular medicine reports 2020 Feb;21(2):597-606
Molecular medicine reports 2020 Feb;21(2):597-606
Network pharmacology based research into the effect and mechanism of Xijiao Dihuang decoction against sepsis.
Lu J, Yan J, Yan J, Zhang L, Chen M, Chen Q, Cheng L, Li P
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Feb;122:109777
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Feb;122:109777
N-WASP knockdown upregulates inflammatory cytokines expression in human gingival fibroblasts.
Wang Y, Kang W, Shang L, Song A, Ge S
Archives of oral biology 2020 Feb;110:104605
Archives of oral biology 2020 Feb;110:104605
Silencing of PTX3 alleviates LPS-induced inflammatory pain by regulating TLR4/NF-κB signaling pathway in mice.
Qi S, Zhao F, Li Z, Liang F, Yu S
Bioscience reports 2020 Feb 28;40(2)
Bioscience reports 2020 Feb 28;40(2)
GDF15 induced by compressive force contributes to osteoclast differentiation in human periodontal ligament cells.
Li S, Li Q, Zhu Y, Hu W
Experimental cell research 2020 Feb 1;387(1):111745
Experimental cell research 2020 Feb 1;387(1):111745
GABA-mediated activated microglia induce neuroinflammation in the hippocampus of mice following cold exposure through the NLRP3 inflammasome and NF-κB signaling pathways.
Lang L, Xu B, Yuan J, Li S, Lian S, Chen Y, Guo J, Yang H
International immunopharmacology 2020 Dec;89(Pt B):106908
International immunopharmacology 2020 Dec;89(Pt B):106908
Protective effect of hydroxysafflor yellow A on dopaminergic neurons against 6-hydroxydopamine, activating anti-apoptotic and anti-neuroinflammatory pathways.
Yang X, Li Y, Chen L, Xu M, Wu J, Zhang P, Nel D, Sun B
Pharmaceutical biology 2020 Dec;58(1):686-694
Pharmaceutical biology 2020 Dec;58(1):686-694
Hepatoprotective effects of Camellia nitidissima aqueous ethanol extract against CCl4-induced acute liver injury in SD rats related to Nrf2 and NF-κB signalling.
Zhang X, Feng J, Su S, Huang L
Pharmaceutical biology 2020 Dec;58(1):239-246
Pharmaceutical biology 2020 Dec;58(1):239-246
Pre-ischemic renal lavage protects against renal ischemia-reperfusion injury by attenuation of local and systemic inflammatory responses.
Guo S, Zhang F, Chen Y, Chen Y, Shushakova N, Yao Y, Zeng R, Li J, Lu X, Chen R, Haller H, Gueler F, Xu G, Rong S
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Dec;34(12):16307-16318
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Dec;34(12):16307-16318
Ameliorative effects and mechanism of crocetin in arsenic trioxide‑induced cardiotoxicity in rats.
Zhao Z, Li J, Zheng B, Liang Y, Shi J, Zhang J, Han X, Chu L, Chu X, Gao Y
Molecular medicine reports 2020 Dec;22(6):5271-5281
Molecular medicine reports 2020 Dec;22(6):5271-5281
Mechanisms underlying the protective effect of tannic acid against arsenic trioxide‑induced cardiotoxicity in rats: Potential involvement of mitochondrial apoptosis.
Xue Y, Li M, Xue Y, Jin W, Han X, Zhang J, Chu X, Li Z, Chu L
Molecular medicine reports 2020 Dec;22(6):4663-4674
Molecular medicine reports 2020 Dec;22(6):4663-4674
Hepatitis B virus core protein promotes the expression of neuraminidase 1 to facilitate hepatocarcinogenesis.
Kong F, Li N, Tu T, Tao Y, Bi Y, Yuan D, Zhang N, Yang X, Kong D, You H, Zheng K, Tang R
Laboratory investigation; a journal of technical methods and pathology 2020 Dec;100(12):1602-1617
Laboratory investigation; a journal of technical methods and pathology 2020 Dec;100(12):1602-1617
Fat Encapsulation Reduces Diarrhea in Piglets Partially by Repairing the Intestinal Barrier and Improving Fatty Acid Transport.
Tian M, Chen J, Wu Z, Song H, Yang F, Cui C, Chen F, Zhang S, Guan W
Animals : an open access journal from MDPI 2020 Dec 26;11(1)
Animals : an open access journal from MDPI 2020 Dec 26;11(1)
Multi-walled carbon nanotubes decrease neuronal NO synthase in 3D brain organoids.
Jiang Y, Gong H, Jiang S, She C, Cao Y
The Science of the total environment 2020 Dec 15;748:141384
The Science of the total environment 2020 Dec 15;748:141384
Chronic ethanol exposure induces neuroinflammation in H4 cells through TLR3 / NF-κB pathway and anxiety-like behavior in male C57BL/6 mice.
Wang X, Yu H, Wang C, Liu Y, You J, Wang P, Xu G, Shen H, Yao H, Lan X, Zhao R, Wu X, Zhang G
Toxicology 2020 Dec 15;446:152625
Toxicology 2020 Dec 15;446:152625
Akebia Saponin D suppresses inflammation in chondrocytes via the NRF2/HO-1/NF-κB axis and ameliorates osteoarthritis in mice.
Gu M, Jin J, Ren C, Chen X, Gao W, Wang X, Wu Y, Tian N, Pan Z, Wu A, Zhou Y, Zhang X
Food & function 2020 Dec 1;11(12):10852-10863
Food & function 2020 Dec 1;11(12):10852-10863
Saturated fatty acids activate the inflammatory signalling pathway in Schwann cells: Implication in sciatic nerve injury.
Xu D, Liang J, Cui M, Zhang L, Ren S, Zheng W, Dong X, Zhang B
Scandinavian journal of immunology 2020 Aug;92(2):e12896
Scandinavian journal of immunology 2020 Aug;92(2):e12896
Glycitin Suppresses Cartilage Destruction of Osteoarthritis in Mice.
Wang W, Yang R, Zhang M, Li J, Peng J, Xu M, Zhao Y, Li H, Pan X
Inflammation 2020 Aug;43(4):1312-1322
Inflammation 2020 Aug;43(4):1312-1322
Neferine Inhibits Expression of Inflammatory Mediators and Matrix Degrading Enzymes in IL-1β-Treated Rat Chondrocytes via Suppressing MAPK and NF-κB Signaling Pathways.
Ni B, Huang X, Xi Y, Mao Z, Chu X, Zhang R, Ma X, You H
Inflammation 2020 Aug;43(4):1209-1221
Inflammation 2020 Aug;43(4):1209-1221
Schisandrin B improves cerebral ischemia and reduces reperfusion injury in rats through TLR4/NF-κB signaling pathway inhibition.
Fan X, Elkin K, Shi Y, Zhang Z, Cheng Y, Gu J, Liang J, Wang C, Ji X
Neurological research 2020 Aug;42(8):693-702
Neurological research 2020 Aug;42(8):693-702
Regorafenib suppresses epidermal growth factor receptor signaling-modulated progression of colorectal cancer.
Liu YC, Tsai JJ, Weng YS, Hsu FT
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Aug;128:110319
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Aug;128:110319
Anti-inflammatory effect of Ganluyin, a Chinese classic prescription, in chronic pharyngitis rat model.
Chen YH, Luo R, Lei SS, Li B, Zhou FC, Wang HY, Chen X, He X, Wang YZ, Zhan LH, Lu TT, Su J, Yu QX, Li B, Lv GY, Chen SH
BMC complementary medicine and therapies 2020 Aug 28;20(1):265
BMC complementary medicine and therapies 2020 Aug 28;20(1):265
Antidepressant-like Effect of Merazin Hydrate Depends on NO/ERK by Suppressing Its Downstream NF-κB or Nonactivating CREB/BDNF in Mouse Hippocampus.
Wu L, Liu X, Huang Y, Lu C, Zhou J, Ren P, Huang X
ACS chemical neuroscience 2020 Aug 19;11(16):2472-2481
ACS chemical neuroscience 2020 Aug 19;11(16):2472-2481
Protective function of exosomes from adipose tissue-derived mesenchymal stem cells in acute kidney injury through SIRT1 pathway.
Gao F, Zuo B, Wang Y, Li S, Yang J, Sun D
Life sciences 2020 Aug 15;255:117719
Life sciences 2020 Aug 15;255:117719
The response of phenoloxidase to cadmium-disturbed hepatopancreatic immune-related molecules in freshwater crayfish Procambarus clarkii.
Wei K, Wei Y, Song C
Fish & shellfish immunology 2020 Apr;99:190-198
Fish & shellfish immunology 2020 Apr;99:190-198
Therapeutic effects of recombinant human brain natriuretic peptide on sepsis-associated encephalopathy in mice.
Li N, Zhang EF, Zhang J, Zhang L, Liu YE, Jin HX, Gao Y, Hou LC
International immunopharmacology 2020 Apr;81:106280
International immunopharmacology 2020 Apr;81:106280
Berberine combined with cyclosporine A alleviates acute graft-versus-host disease in murine models.
Wang M, Zhang J, Zhao H, Wan D, Jiang Z
International immunopharmacology 2020 Apr;81:106205
International immunopharmacology 2020 Apr;81:106205
p-Coumaric Acid Attenuates IL-1β-Induced Inflammatory Responses and Cellular Senescence in Rat Chondrocytes.
Huang X, You Y, Xi Y, Ni B, Chu X, Zhang R, You H
Inflammation 2020 Apr;43(2):619-628
Inflammation 2020 Apr;43(2):619-628
HMGB1 Mediates Paraquat-Induced Neuroinflammatory Responses via Activating RAGE Signaling Pathway.
Huang M, Guo M, Wang K, Wu K, Li Y, Tian T, Wang Y, Yan W, Zhou Z, Yang H
Neurotoxicity research 2020 Apr;37(4):913-925
Neurotoxicity research 2020 Apr;37(4):913-925
Icariside II attenuates eosinophils-induced airway inflammation and remodeling via inactivation of NF-κB and STAT3 in an asthma mouse model.
Tian C, Gao F, Li X, Li Z
Experimental and molecular pathology 2020 Apr;113:104373
Experimental and molecular pathology 2020 Apr;113:104373
A Combination of Formic Acid and Monolaurin Attenuates Enterotoxigenic Escherichia coli Induced Intestinal Inflammation in Piglets by Inhibiting the NF-κB/MAPK Pathways with Modulation of Gut Microbiota.
Ren C, Wang Y, Lin X, Song H, Zhou Q, Xu W, Shi K, Chen J, Song J, Chen F, Zhang S, Guan W
Journal of agricultural and food chemistry 2020 Apr 8;68(14):4155-4165
Journal of agricultural and food chemistry 2020 Apr 8;68(14):4155-4165
Anti-neuroinflammatory effects of dimethylaminomylide (DMAMCL, i.e., ACT001) are associated with attenuating the NLRP3 inflammasome in MPTP-induced Parkinson disease in mice.
Liu Q, Guo X, Huang Z, He Q, Zhu D, Zhang S, Peng Z, Che Y, Feng X
Behavioural brain research 2020 Apr 6;383:112539
Behavioural brain research 2020 Apr 6;383:112539
Hot-water extract of ripened Pu-erh tea attenuates DSS-induced colitis through modulation of the NF-κB and HIF-1α signaling pathways in mice.
Huang Y, Qiu L, Mi X, Zhang Z, Xu D, Tao X, Xing K, Wu Q, Wei H
Food & function 2020 Apr 30;11(4):3459-3470
Food & function 2020 Apr 30;11(4):3459-3470
Liquiritin, a novel inhibitor of TRPV1 and TRPA1, protects against LPS-induced acute lung injury.
Liu Z, Wang P, Lu S, Guo R, Gao W, Tong H, Yin Y, Han X, Liu T, Chen X, Zhu MX, Yang Z
Cell calcium 2020 Apr 28;88:102198
Cell calcium 2020 Apr 28;88:102198
Wu-Mei-Wan ameliorates chronic colitis-associated intestinal fibrosis through inhibiting fibroblast activation.
Wu F, Shao Q, Hu M, Zhao Y, Dong R, Fang K, Xu L, Zou X, Lu F, Li J, Chen G
Journal of ethnopharmacology 2020 Apr 24;252:112580
Journal of ethnopharmacology 2020 Apr 24;252:112580
Interleukin-17 suppresses grass carp reovirus infection in Ctenopharyngodon idellus kidney cells by activating NF-κB signaling.
Zhang Y, Zhang X, Liang Z, Dai K, Zhu M, Zhang M, Pan J, Xue R, Cao G, Tang J, Song X, Hu X, Gong C
Aquaculture (Amsterdam, Netherlands) 2020 Apr 15;520:734969
Aquaculture (Amsterdam, Netherlands) 2020 Apr 15;520:734969
Silica particles disorganize the polarization of pulmonary macrophages in mice.
Zhao Y, Hao C, Bao L, Wang D, Li Y, Qu Y, Ding M, Zhao A, Yao W
Ecotoxicology and environmental safety 2020 Apr 15;193:110364
Ecotoxicology and environmental safety 2020 Apr 15;193:110364
NUDT21 inhibits bladder cancer progression through ANXA2 and LIMK2 by alternative polyadenylation.
Xiong M, Chen L, Zhou L, Ding Y, Kazobinka G, Chen Z, Hou T
Theranostics 2019;9(24):7156-7167
Theranostics 2019;9(24):7156-7167
Copy number gain of ZEB1 mediates a double-negative feedback loop with miR-33a-5p that regulates EMT and bone metastasis of prostate cancer dependent on TGF-β signaling.
Dai Y, Wu Z, Lang C, Zhang X, He S, Yang Q, Guo W, Lai Y, Du H, Peng X, Ren D
Theranostics 2019;9(21):6063-6079
Theranostics 2019;9(21):6063-6079
Nanozyme-mediated catalytic nanotherapy for inflammatory bowel disease.
Zhao J, Gao W, Cai X, Xu J, Zou D, Li Z, Hu B, Zheng Y
Theranostics 2019;9(10):2843-2855
Theranostics 2019;9(10):2843-2855
Scorpion Venom Analgesic Peptide, BmK AGAP Inhibits Stemness, and Epithelial-Mesenchymal Transition by Down-Regulating PTX3 in Breast Cancer.
Kampo S, Ahmmed B, Zhou T, Owusu L, Anabah TW, Doudou NR, Kuugbee ED, Cui Y, Lu Z, Yan Q, Wen QP
Frontiers in oncology 2019;9:21
Frontiers in oncology 2019;9:21
Decreased miR-218-5p Levels as a Serum Biomarker in Bone Metastasis of Prostate Cancer.
Peng P, Chen T, Wang Q, Zhang Y, Zheng F, Huang S, Tang Y, Yang C, Ding W, Ren D, Huang Z, Guo Y
Oncology research and treatment 2019;42(4):165-185
Oncology research and treatment 2019;42(4):165-185
MicroRNA-145 Protects against Myocardial Ischemia Reperfusion Injury via CaMKII-Mediated Antiapoptotic and Anti-Inflammatory Pathways.
Liu Z, Tao B, Fan S, Pu Y, Xia H, Xu L
Oxidative medicine and cellular longevity 2019;2019:8948657
Oxidative medicine and cellular longevity 2019;2019:8948657
Protective Effect of Methane-Rich Saline on Acetic Acid-Induced Ulcerative Colitis via Blocking the TLR4/NF-κB/MAPK Pathway and Promoting IL-10/JAK1/STAT3-Mediated Anti-inflammatory Response.
Wang G, Xu B, Shi F, Du M, Li Y, Yu T, Chen L
Oxidative medicine and cellular longevity 2019;2019:7850324
Oxidative medicine and cellular longevity 2019;2019:7850324
Aloin Preconditioning Attenuates Hepatic Ischemia/Reperfusion Injury via Inhibiting TLR4/MyD88/NF-κB Signal Pathway In Vivo and In Vitro.
Du Y, Qian B, Gao L, Tan P, Chen H, Wang A, Zheng T, Pu S, Xia X, Fu W
Oxidative medicine and cellular longevity 2019;2019:3765898
Oxidative medicine and cellular longevity 2019;2019:3765898
Secretory leukocyte protease inhibitor suppresses HPV E6-expressing HNSCC progression by mediating NF-κB and Akt pathways.
Jin Y, Li Y, Wang X, Yang Y
Cancer cell international 2019;19:220
Cancer cell international 2019;19:220
HIV-1-infected cell-derived exosomes promote the growth and progression of cervical cancer.
Li H, Chi X, Li R, Ouyang J, Chen Y
International journal of biological sciences 2019;15(11):2438-2447
International journal of biological sciences 2019;15(11):2438-2447
Antitumor activity of a novel dual functional podophyllotoxin derivative involved PI3K/AKT/mTOR pathway.
Li Y, Huang T, Fu Y, Wang T, Zhao T, Guo S, Sun Y, Yang Y, Li C
PloS one 2019;14(9):e0215886
PloS one 2019;14(9):e0215886
ETA-mediated anti-TNF-α therapy ameliorates the phenotype of PCOS model induced by letrozole.
Lang Q, Yidong X, Xueguang Z, Sixian W, Wenming X, Tao Z
PloS one 2019;14(6):e0217495
PloS one 2019;14(6):e0217495
Synergism of cisplatin-oleanolic acid co-loaded calcium carbonate nanoparticles on hepatocellular carcinoma cells for enhanced apoptosis and reduced hepatotoxicity.
Khan MW, Zhao P, Khan A, Raza F, Raza SM, Sarfraz M, Chen Y, Li M, Yang T, Ma X, Xiang G
International journal of nanomedicine 2019;14:3753-3771
International journal of nanomedicine 2019;14:3753-3771
Exosomes Derived From Bone Marrow Mesenchymal Stem Cells Inhibit Complement Activation In Rats With Spinal Cord Injury.
Zhao C, Zhou X, Qiu J, Xin D, Li T, Chu X, Yuan H, Wang H, Wang Z, Wang D
Drug design, development and therapy 2019;13:3693-3704
Drug design, development and therapy 2019;13:3693-3704
Dioscin ameliorates peritoneal fibrosis by inhibiting epithelial-to-mesenchymal transition of human peritoneal mesothelial cells via the TLR4/MyD88/NF-κB signaling pathway.
Shao Q, Jiang C, Xia Y, Zhao M, Zhang Q, Jin B, Liu J
International journal of clinical and experimental pathology 2019;12(3):867-875
International journal of clinical and experimental pathology 2019;12(3):867-875
Hydrocortisone Suppresses Early Paraneoplastic Inflammation And Angiogenesis To Attenuate Early Hepatocellular Carcinoma Progression In Rats.
Liu X, Cui H, Niu H, Wang L, Li X, Sun J, Wei Q, Dong J, Liu L, Xian CJ
OncoTargets and therapy 2019;12:9481-9493
OncoTargets and therapy 2019;12:9481-9493
L-Cysteine-Derived H(2)S Promotes Microglia M2 Polarization via Activation of the AMPK Pathway in Hypoxia-Ischemic Neonatal Mice.
Zhou X, Chu X, Xin D, Li T, Bai X, Qiu J, Yuan H, Liu D, Wang D, Wang Z
Frontiers in molecular neuroscience 2019;12:58
Frontiers in molecular neuroscience 2019;12:58
ITGBL1 promotes EMT, invasion and migration by activating NF-κB signaling pathway in prostate cancer.
Li W, Li S, Yang J, Cui C, Yu M, Zhang Y
OncoTargets and therapy 2019;12:3753-3763
OncoTargets and therapy 2019;12:3753-3763
SIRT4 inhibits the proliferation, migration, and invasion abilities of thyroid cancer cells by inhibiting glutamine metabolism.
Chen Z, Lin J, Feng S, Chen X, Huang H, Wang C, Yu Y, He Y, Han S, Zheng L, Huang G
OncoTargets and therapy 2019;12:2397-2408
OncoTargets and therapy 2019;12:2397-2408
Monitoring the Early Antiproliferative Effect of the Analgesic-Antitumor Peptide, BmK AGAP on Breast Cancer Using Intravoxel Incoherent Motion With a Reduced Distribution of Four b-Values.
Doudou NR, Kampo S, Liu Y, Ahmmed B, Zeng D, Zheng M, Mohamadou A, Wen QP, Wang S
Frontiers in physiology 2019;10:708
Frontiers in physiology 2019;10:708
Nobiletin Inhibits IL-1β-Induced Inflammation in Chondrocytes via Suppression of NF-κB Signaling and Attenuates Osteoarthritis in Mice.
Lin Z, Wu D, Huang L, Jiang C, Pan T, Kang X, Pan J
Frontiers in pharmacology 2019;10:570
Frontiers in pharmacology 2019;10:570
Schisandrin A Inhibits the IL-1β-Induced Inflammation and Cartilage Degradation via Suppression of MAPK and NF-κB Signal Pathways in Rat Chondrocytes.
Tu C, Huang X, Xiao Y, Song M, Ma Y, Yan J, You H, Wu H
Frontiers in pharmacology 2019;10:41
Frontiers in pharmacology 2019;10:41
Gardenia Decoction Prevent Intestinal Mucosal Injury by Inhibiting Pro-inflammatory Cytokines and NF-κB Signaling.
Cui Y, Wang Q, Wang M, Jia J, Wu R
Frontiers in pharmacology 2019;10:180
Frontiers in pharmacology 2019;10:180
Trimetazidine Attenuates Exhaustive Exercise-Induced Myocardial Injury in Rats via Regulation of the Nrf2/NF-κB Signaling Pathway.
Zhang H, Liu M, Zhang Y, Li X
Frontiers in pharmacology 2019;10:175
Frontiers in pharmacology 2019;10:175
The Therapeutic Effects of Treadmill Exercise on Osteoarthritis in Rats by Inhibiting the HDAC3/NF-KappaB Pathway in vivo and in vitro.
Zhang H, Ji L, Yang Y, Wei Y, Zhang X, Gang Y, Lu J, Bai L
Frontiers in physiology 2019;10:1060
Frontiers in physiology 2019;10:1060
Protective Effects of Dioscin Against Doxorubicin-Induced Hepatotoxicity Via Regulation of Sirt1/FOXO1/NF-κb Signal.
Song S, Chu L, Liang H, Chen J, Liang J, Huang Z, Zhang B, Chen X
Frontiers in pharmacology 2019;10:1030
Frontiers in pharmacology 2019;10:1030
Correction to: Protective effects of dioscin against alcohol‑induced liver injury.
Xu T, Zheng L, Xu L, Yin L, Qi Y, Xu Y, Han X, Peng J
Archives of toxicology 2019 Sep;93(9):2713
Archives of toxicology 2019 Sep;93(9):2713
Sedum sarmentosum Bunge extract alleviates inflammation and kidney injury via inhibition of M1-macrophage polarization.
Lu H, Cheng S, Wu C, Zheng S, Hong W, Liu L, Bai Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2019 Sep;62:152976
Phytomedicine : international journal of phytotherapy and phytopharmacology 2019 Sep;62:152976
Epstein-Barr virus tegument protein BGLF2 inhibits NF-κB activity by preventing p65 Ser536 phosphorylation.
Chen T, Wang Y, Xu Z, Zou X, Wang P, Ou X, Li Y, Peng T, Chen D, Li M, Cai M
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Sep;33(9):10563-10576
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Sep;33(9):10563-10576
Liquiritigenin inhibits IL-1β-induced inflammation and cartilage matrix degradation in rat chondrocytes.
Tu C, Ma Y, Song M, Yan J, Xiao Y, Wu H
European journal of pharmacology 2019 Sep 5;858:172445
European journal of pharmacology 2019 Sep 5;858:172445
Inhibition of MCF-7 breast cancer cell proliferation by a synthetic peptide derived from the C-terminal sequence of Orai channel.
Li S, Yao M, Niu C, Liu D, Tang Z, Gu C, Zhao H, Ke J, Wu S, Wang X, Wu F
Biochemical and biophysical research communications 2019 Sep 3;516(4):1066-1072
Biochemical and biophysical research communications 2019 Sep 3;516(4):1066-1072
Vanillic acid attenuates cartilage degeneration by regulating the MAPK and PI3K/AKT/NF-κB pathways.
Huang X, Xi Y, Mao Z, Chu X, Zhang R, Ma X, Ni B, Cheng H, You H
European journal of pharmacology 2019 Sep 15;859:172481
European journal of pharmacology 2019 Sep 15;859:172481
Ginkgo Biloba Extract Inhibits Metastasis and ERK/Nuclear Factor kappa B (NF-κB) Signaling Pathway in Gastric Cancer.
Fu Z, Lin L, Liu S, Qin M, He S, Zhu L, Huang J
Medical science monitor : international medical journal of experimental and clinical research 2019 Sep 11;25:6836-6845
Medical science monitor : international medical journal of experimental and clinical research 2019 Sep 11;25:6836-6845
Suppression of miR-143 contributes to overexpression of IL-6, HIF-1α and NF-κB p65 in Cr(VI)-induced human exposure and tumor growth.
Wang L, Qiu JG, He J, Liu WJ, Ge X, Zhou FM, Huang YX, Jiang BH, Liu LZ
Toxicology and applied pharmacology 2019 Sep 1;378:114603
Toxicology and applied pharmacology 2019 Sep 1;378:114603
Naringin mitigates myocardial strain and the inflammatory response in sepsis-induced myocardial dysfunction through regulation of PI3K/AKT/NF-κB pathway.
Sun LJ, Qiao W, Xiao YJ, Cui L, Wang X, Ren WD
International immunopharmacology 2019 Oct;75:105782
International immunopharmacology 2019 Oct;75:105782
Limonin ameliorates ulcerative colitis by regulating STAT3/miR-214 signaling pathway.
Liu S, Zhang S, Lv X, Lu J, Ren C, Zeng Z, Zheng L, Zhou X, Fu H, Zhou D, Chen Y
International immunopharmacology 2019 Oct;75:105768
International immunopharmacology 2019 Oct;75:105768
AEBP1, a prognostic indicator, promotes colon adenocarcinoma cell growth and metastasis through the NF-κB pathway.
Xing Y, Zhang Z, Chi F, Zhou Y, Ren S, Zhao Z, Zhu Y, Piao D
Molecular carcinogenesis 2019 Oct;58(10):1795-1808
Molecular carcinogenesis 2019 Oct;58(10):1795-1808
Dioscin attenuates Bleomycin-Induced acute lung injury via inhibiting the inflammatory response in mice.
Wu ZL, Wang J
Experimental lung research 2019 Oct;45(8):236-244
Experimental lung research 2019 Oct;45(8):236-244
Semaphorin 4C Promotes Macrophage Recruitment and Angiogenesis in Breast Cancer.
Yang J, Zeng Z, Qiao L, Jiang X, Ma J, Wang J, Ye S, Ma Q, Wei J, Wu M, Huang X, Ma D, Gao Q
Molecular cancer research : MCR 2019 Oct;17(10):2015-2028
Molecular cancer research : MCR 2019 Oct;17(10):2015-2028
Induction of PGRN by influenza virus inhibits the antiviral immune responses through downregulation of type I interferons signaling.
Wei F, Jiang Z, Sun H, Pu J, Sun Y, Wang M, Tong Q, Bi Y, Ma X, Gao GF, Liu J
PLoS pathogens 2019 Oct;15(10):e1008062
PLoS pathogens 2019 Oct;15(10):e1008062
Disocin prevents postmenopausal atherosclerosis in ovariectomized LDLR-/- mice through a PGC-1α/ERα pathway leading to promotion of autophagy and inhibition of oxidative stress, inflammation and apoptosis.
Yang Q, Wang C, Jin Y, Ma X, Xie T, Wang J, Liu K, Sun H
Pharmacological research 2019 Oct;148:104414
Pharmacological research 2019 Oct;148:104414
FNDC5 inhibits foam cell formation and monocyte adhesion in vascular smooth muscle cells via suppressing NFκB-mediated NLRP3 upregulation.
Zang YH, Chen D, Zhou B, Chen AD, Wang JJ, Gao XY, Chen Q, Li YH, Kang YM, Zhu GQ
Vascular pharmacology 2019 Oct;121:106579
Vascular pharmacology 2019 Oct;121:106579
Dehydroepiandrosterone alleviates E. Coli O157:H7-induced inflammation by preventing the activation of p38 MAPK and NF-κB pathways in mice peritoneal macrophages.
Zhao J, Cao J, Yu L, Ma H
Molecular immunology 2019 Oct;114:114-122
Molecular immunology 2019 Oct;114:114-122
γ-Oryzanol alleviates acetaminophen-induced liver injury: roles of modulating AMPK/GSK3β/Nrf2 and NF-κB signaling pathways.
Shu G, Qiu Y, Hao J, Fu Q, Deng X
Food & function 2019 Oct 16;10(10):6858-6872
Food & function 2019 Oct 16;10(10):6858-6872
Decreased RIPK1 expression in chondrocytes alleviates osteoarthritis via the TRIF/MyD88-RIPK1-TRAF2 negative feedback loop.
Liang S, Wang ZG, Zhang ZZ, Chen K, Lv ZT, Wang YT, Cheng P, Sun K, Yang Q, Chen AM
Aging 2019 Oct 11;11(19):8664-8680
Aging 2019 Oct 11;11(19):8664-8680
Light-induced Nrf2-/- mice as atrophic age-related macular degeneration model and treatment with nanoceria laden injectable hydrogel.
Wang K, Zheng M, Lester KL, Han Z
Scientific reports 2019 Oct 10;9(1):14573
Scientific reports 2019 Oct 10;9(1):14573
Synthesis and biological evaluation of (1,2,4)triazole[4,3-a]pyridine derivatives as potential therapeutic agents for concanavalin A-induced hepatitis.
Shi Y, Wang Q, Rong J, Ren J, Song X, Fan X, Shen M, Xia Y, Wang N, Liu Z, Hu Q, Ye T, Yu L
European journal of medicinal chemistry 2019 Oct 1;179:182-195
European journal of medicinal chemistry 2019 Oct 1;179:182-195
TIPE2 ameliorates lipopolysaccharide-induced apoptosis and inflammation in acute lung injury.
Wu X, Kong Q, Zhan L, Qiu Z, Huang Q, Song X
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2019 Nov;68(11):981-992
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2019 Nov;68(11):981-992
Neuroprotection of Andrographolide Against Microglia-Mediated Inflammatory Injury and Oxidative Damage in PC12 Neurons.
Xu Y, Tang D, Wang J, Wei H, Gao J
Neurochemical research 2019 Nov;44(11):2619-2630
Neurochemical research 2019 Nov;44(11):2619-2630
Effect of Intranasal Instillation of Lipopolysaccharide on Lung Development and Its Related Mechanism in Newborn Mice.
You Y, Guo C, Zhang H, Deng S, Tang J, Xu L, Deng C, Gong F
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2019 Nov;39(11):684-693
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2019 Nov;39(11):684-693
Nonviral Delivery of GRIM-19 Gene Inhibits Tumor Growth with Reduced Local and Systemic Complications.
Xu Y, Wang X, Guo B, Wang D, Kalvakolanu DV, Chen X, Tang J, Zhang L, Yang Q
Human gene therapy 2019 Nov;30(11):1419-1430
Human gene therapy 2019 Nov;30(11):1419-1430
Morin reduces inflammatory responses and alleviates lipid accumulation in hepatocytes.
Wu L, Wang Y, Chi G, Shen B, Tian Y, Li Z, Han L, Zhang Q, Feng H
Journal of cellular physiology 2019 Nov;234(11):19785-19798
Journal of cellular physiology 2019 Nov;234(11):19785-19798
Downregulation of transgelin 2 promotes breast cancer metastasis by activating the reactive oxygen species/nuclear factor‑κB signaling pathway.
Yang L, Hong Q, Xu SG, Kuang XY, Di GH, Liu GY, Wu J, Shao ZM, Yu SJ
Molecular medicine reports 2019 Nov;20(5):4045-4258
Molecular medicine reports 2019 Nov;20(5):4045-4258
Repression of eEF2K transcription by NF-κB tunes translation elongation to inflammation and dsDNA-sensing.
Bianco C, Thompson L, Mohr I
Proceedings of the National Academy of Sciences of the United States of America 2019 Nov 5;116(45):22583-22590
Proceedings of the National Academy of Sciences of the United States of America 2019 Nov 5;116(45):22583-22590
Porcine Circovirus Type 2 Induces Single Immunoglobulin Interleukin-1 Related Receptor (SIGIRR) Downregulation to Promote Interleukin-1β Upregulation in Porcine Alveolar Macrophage.
Yang S, Liu B, Yin S, Shang Y, Zhang X, Khan MUZ, Liu X, Cai J
Viruses 2019 Nov 3;11(11)
Viruses 2019 Nov 3;11(11)
Ameliorative effects of echinacoside against spinal cord injury via inhibiting NLRP3 inflammasome signaling pathway.
Gao S, Xu T, Guo H, Deng Q, Xun C, Liang W, Sheng W
Life sciences 2019 Nov 15;237:116978
Life sciences 2019 Nov 15;237:116978
Deoxynivalenol Induces Intestinal Damage and Inflammatory Response through the Nuclear Factor-κB Signaling Pathway in Piglets.
Wang XC, Zhang YF, Cao L, Zhu L, Huang YY, Chen XF, Chu XY, Zhu DF, Ur Rahman S, Feng SB, Li Y, Wu JJ
Toxins 2019 Nov 14;11(11)
Toxins 2019 Nov 14;11(11)
SPOP inhibits mice pancreatic stellate cell activation by promoting FADD degradation in cerulein-induced chronic pancreatitis.
Tan P, Wang A, Chen H, Du Y, Qian B, Shi H, Zhang Y, Xia X, Fu W
Experimental cell research 2019 Nov 1;384(1):111606
Experimental cell research 2019 Nov 1;384(1):111606
Response of the maternal hypothalamus to cold stress during late pregnancy in rats.
Wang D, Xu B, Wang J, Wang H, Guo J, Ji H, Li S, Wu R, Yang H, Lian S
Brain research 2019 Nov 1;1722:146354
Brain research 2019 Nov 1;1722:146354
Regulating glycolysis, the TLR4 signal pathway and expression of RBM3 in mouse liver in response to acute cold exposure.
Shi H, Yao R, Lian S, Liu P, Liu Y, Yang YY, Yang H, Li S
Stress (Amsterdam, Netherlands) 2019 May;22(3):366-376
Stress (Amsterdam, Netherlands) 2019 May;22(3):366-376
Adeno-associated virus 9-mediated RNA interference targeting SOCS3 alleviates diastolic heart failure in rats.
Gao J, Guo Y, Chen Y, Zhou J, Liu Y, Su P
Gene 2019 May 20;697:11-18
Gene 2019 May 20;697:11-18
PKM2 is the target of proanthocyanidin B2 during the inhibition of hepatocellular carcinoma.
Feng J, Wu L, Ji J, Chen K, Yu Q, Zhang J, Chen J, Mao Y, Wang F, Dai W, Xu L, Wu J, Guo C
Journal of experimental & clinical cancer research : CR 2019 May 17;38(1):204
Journal of experimental & clinical cancer research : CR 2019 May 17;38(1):204
Comparison of the Hepatoprotective Effects of the Three Main Stilbenes from Mulberry Twigs.
Jia YN, Peng YL, Zhao YP, Cheng XF, Zhou Y, Chai CL, Zeng LS, Pan MH, Xu L
Journal of agricultural and food chemistry 2019 May 15;67(19):5521-5529
Journal of agricultural and food chemistry 2019 May 15;67(19):5521-5529
Hepatoprotective effects and structure-activity relationship of five flavonoids against lipopolysaccharide/d-galactosamine induced acute liver failure in mice.
He Y, Xia Z, Yu D, Wang J, Jin L, Huang D, Ye X, Li X, Zhang B
International immunopharmacology 2019 Mar;68:171-178
International immunopharmacology 2019 Mar;68:171-178
MiR-101a ameliorates AngII-mediated hypertensive nephropathy by blockade of TGFβ/Smad3 and NF-κB signalling in a mouse model of hypertension.
Ding H, Zhou Y, Huang H
Clinical and experimental pharmacology & physiology 2019 Mar;46(3):246-254
Clinical and experimental pharmacology & physiology 2019 Mar;46(3):246-254
NF-κB and Poly (ADP-ribose) Polymerase 1 Form a Positive Feedback Loop that Regulates DNA Repair in Acute Myeloid Leukemia Cells.
Li D, Luo Y, Chen X, Zhang L, Wang T, Zhuang Y, Fan Y, Xu J, Chen Y, Wu L
Molecular cancer research : MCR 2019 Mar;17(3):761-772
Molecular cancer research : MCR 2019 Mar;17(3):761-772
Betulinic acid suppresses breast cancer aerobic glycolysis via caveolin-1/NF-κB/c-Myc pathway.
Jiao L, Wang S, Zheng Y, Wang N, Yang B, Wang D, Yang D, Mei W, Zhao Z, Wang Z
Biochemical pharmacology 2019 Mar;161:149-162
Biochemical pharmacology 2019 Mar;161:149-162
Pharmacological preconditioning with the cellular stress inducer thapsigargin protects against experimental sepsis.
Wei Y, Meng M, Tian Z, Xie F, Yin Q, Dai C, Wang J, Zhang Q, Liu Y, Liu C, Yan F, Jiang F, Guo X
Pharmacological research 2019 Mar;141:114-122
Pharmacological research 2019 Mar;141:114-122
Combinatory FK506 and Minocycline Treatment Alleviates Prion-Induced Neurodegenerative Events via Caspase-Mediated MAPK-NRF2 Pathway.
Shah SZA, Zhao D, Taglialatela G, Hussain T, Dong H, Sabir N, Mangi MH, Wu W, Lai M, Zhang X, Duan Y, Wang L, Zhou X, Yang L
International journal of molecular sciences 2019 Mar 6;20(5)
International journal of molecular sciences 2019 Mar 6;20(5)
COMMD7 Regulates NF-κB Signaling Pathway in Hepatocellular Carcinoma Stem-like Cells.
Zheng L, You N, Huang X, Gu H, Wu K, Mi N, Li J
Molecular therapy oncolytics 2019 Mar 29;12:112-123
Molecular therapy oncolytics 2019 Mar 29;12:112-123
Mucin 1 downregulation impairs the anti-necroptotic effects of glucocorticoids in human bronchial epithelial cells.
Zhang H, Liu Q, Kong L, Xu S
Life sciences 2019 Mar 15;221:168-177
Life sciences 2019 Mar 15;221:168-177
In Vitro and In Vivo Anti-Inflammatory Effects of Polyphyllin VII through Downregulating MAPK and NF-κB Pathways.
Zhang C, Li C, Jia X, Wang K, Tu Y, Wang R, Liu K, Lu T, He C
Molecules (Basel, Switzerland) 2019 Mar 1;24(5)
Molecules (Basel, Switzerland) 2019 Mar 1;24(5)
Downregulation of TIMP2 attenuates sepsis-induced AKI through the NF-κb pathway.
Li YM, Zhang J, Su LJ, Kellum JA, Peng ZY
Biochimica et biophysica acta. Molecular basis of disease 2019 Mar 1;1865(3):558-569
Biochimica et biophysica acta. Molecular basis of disease 2019 Mar 1;1865(3):558-569
Leonurine alleviates LPS-induced myocarditis through suppressing the NF-кB signaling pathway.
Wang R, Li D, Ouyang J, Tian X, Zhao Y, Peng X, Li S, Yu G, Yang J
Toxicology 2019 Jun 15;422:1-13
Toxicology 2019 Jun 15;422:1-13
Aspirin targets P4HA2 through inhibiting NF-κB and LMCD1-AS1/let-7g to inhibit tumour growth and collagen deposition in hepatocellular carcinoma.
Wang T, Fu X, Jin T, Zhang L, Liu B, Wu Y, Xu F, Wang X, Ye K, Zhang W, Ye L
EBioMedicine 2019 Jul;45:168-180
EBioMedicine 2019 Jul;45:168-180
Effect of Astragalus membranaceus in Ovalbumin-Induced Allergic Rhinitis Mouse Model.
Bing Z, Jin-Tao D, Feng L, Ba L, Ya-Feng L, Shi-Xi L
American journal of rhinology & allergy 2019 Jul;33(4):420-432
American journal of rhinology & allergy 2019 Jul;33(4):420-432
Chlorogenic acid: A potent molecule that protects cardiomyocytes from TNF-α-induced injury via inhibiting NF-κB and JNK signals.
Tian L, Su CP, Wang Q, Wu FJ, Bai R, Zhang HM, Liu JY, Lu WJ, Wang W, Lan F, Guo SZ
Journal of cellular and molecular medicine 2019 Jul;23(7):4666-4678
Journal of cellular and molecular medicine 2019 Jul;23(7):4666-4678
GABAB receptor activation attenuates inflammatory orofacial pain by modulating interleukin-1β in satellite glial cells: Role of NF-κB and MAPK signaling pathways.
Liu F, Zhang YY, Song N, Lin J, Liu MK, Huang CL, Zhou C, Wang H, Wang M, Shen JF
Brain research bulletin 2019 Jul;149:240-250
Brain research bulletin 2019 Jul;149:240-250
Matrine inhibits IL-1β secretion in primary porcine alveolar macrophages through the MyD88/NF-κB pathway and NLRP3 inflammasome.
Sun P, Sun N, Yin W, Sun Y, Fan K, Guo J, Khan A, He Y, Li H
Veterinary research 2019 Jul 12;50(1):53
Veterinary research 2019 Jul 12;50(1):53
Suppressive effect mediated by human adipose-derived stem cells on T cells involves the activation of JNK.
Wang Y, Wang X, Zhou X, Zhu Z, Yang J, Liu F
International journal of molecular medicine 2019 Jan;43(1):177-184
International journal of molecular medicine 2019 Jan;43(1):177-184
Dioscin ameliorates intestinal ischemia/reperfusion injury via adjusting miR-351-5p/MAPK13-mediated inflammation and apoptosis.
Zheng L, Han X, Hu Y, Zhao X, Yin L, Xu L, Qi Y, Xu Y, Han X, Liu K, Peng J
Pharmacological research 2019 Jan;139:431-439
Pharmacological research 2019 Jan;139:431-439
LncRNA NKILA regulates endothelium inflammation by controlling a NF-κB/KLF4 positive feedback loop.
Zhu X, Du J, Yu J, Guo R, Feng Y, Qiao L, Xu Z, Yang F, Zhong G, Liu F, Cheng F, Chu M, Lin J
Journal of molecular and cellular cardiology 2019 Jan;126:60-69
Journal of molecular and cellular cardiology 2019 Jan;126:60-69
miR-196a-5p promotes metastasis of colorectal cancer via targeting IκBα.
Xin H, Wang C, Liu Z
BMC cancer 2019 Jan 8;19(1):30
BMC cancer 2019 Jan 8;19(1):30
Star-related lipid transfer protein 10 (STARD10): a novel key player in alcohol-induced breast cancer progression.
Floris A, Luo J, Frank J, Zhou J, Orrù S, Biancolella M, Pucci S, Orlandi A, Campagna P, Balzano A, Ramani K, Tomasi ML
Journal of experimental & clinical cancer research : CR 2019 Jan 5;38(1):4
Journal of experimental & clinical cancer research : CR 2019 Jan 5;38(1):4
Tumor stem-like cell-derived exosomal RNAs prime neutrophils for facilitating tumorigenesis of colon cancer.
Hwang WL, Lan HY, Cheng WC, Huang SC, Yang MH
Journal of hematology & oncology 2019 Jan 25;12(1):10
Journal of hematology & oncology 2019 Jan 25;12(1):10
HMGB1-mediated differential response on hippocampal neurotransmitter disorder and neuroinflammation in adolescent male and female mice following cold exposure.
Xu B, Zang SC, Li SZ, Guo JR, Wang JF, Wang D, Zhang LP, Yang HM, Lian S
Brain, behavior, and immunity 2019 Feb;76:223-235
Brain, behavior, and immunity 2019 Feb;76:223-235
Curcumin relieves depressive-like behaviors via inhibition of the NLRP3 inflammasome and kynurenine pathway in rats suffering from chronic unpredictable mild stress.
Zhang WY, Guo YJ, Han WX, Yang MQ, Wen LP, Wang KY, Jiang P
International immunopharmacology 2019 Feb;67:138-144
International immunopharmacology 2019 Feb;67:138-144
Catalpol Inhibits Homocysteine-induced Oxidation and Inflammation via Inhibiting Nox4/NF-κB and GRP78/PERK Pathways in Human Aorta Endothelial Cells.
Hu H, Wang C, Jin Y, Meng Q, Liu Q, Liu Z, Liu K, Liu X, Sun H
Inflammation 2019 Feb;42(1):64-80
Inflammation 2019 Feb;42(1):64-80
Silencing of LncRNA steroid receptor RNA activator attenuates polycystic ovary syndrome in mice.
Li Y, Zhao W, Wang H, Chen C, Zhou D, Li S, Zhang X, Zhao H, Zhou D, Chen B
Biochimie 2019 Feb;157:48-56
Biochimie 2019 Feb;157:48-56
The mitochondrial chaperone Prohibitin 1 negatively regulates interleukin-8 in human liver cancers.
Yang JW, Murray B, Barbier-Torres L, Liu T, Liu Z, Yang H, Fan W, Wang J, Li Y, Seki E, Mato JM, Lu SC
The Journal of biological chemistry 2019 Feb 8;294(6):1984-1996
The Journal of biological chemistry 2019 Feb 8;294(6):1984-1996
Adipose-derived mesenchymal stem cells ameliorate the inflammatory reaction in CLP-induced septic acute lung injury rats via sTNFR1.
Ding XF, Liang HY, Sun JY, Liu SH, Kan QC, Wang LX, Sun TW
Journal of cellular physiology 2019 Feb 18;
Journal of cellular physiology 2019 Feb 18;
Dihydroartemisinin attenuates lipopolysaccharide‑induced acute lung injury in mice by suppressing NF‑κB signaling in an Nrf2‑dependent manner.
Huang XT, Liu W, Zhou Y, Hao CX, Zhou Y, Zhang CY, Sun CC, Luo ZQ, Tang SY
International journal of molecular medicine 2019 Dec;44(6):2213-2222
International journal of molecular medicine 2019 Dec;44(6):2213-2222
Olean-28,13b-olide 2 plays a role in cisplatin-mediated apoptosis and reverses cisplatin resistance in human lung cancer through multiple signaling pathways.
Zhu B, Ren C, Du K, Zhu H, Ai Y, Kang F, Luo Y, Liu W, Wang L, Xu Y, Jiang X, Zhang Y
Biochemical pharmacology 2019 Dec;170:113642
Biochemical pharmacology 2019 Dec;170:113642
Activating macrophages for enhanced osteogenic and bactericidal performance by Cu ion release from micro/nano-topographical coating on a titanium substrate.
Huang Q, Ouyang Z, Tan Y, Wu H, Liu Y
Acta biomaterialia 2019 Dec;100:415-426
Acta biomaterialia 2019 Dec;100:415-426
Rice Protein Exerts Anti-Inflammatory Effect in Growing and Adult Rats via Suppressing NF-κB Pathway.
Wang Z, Liang M, Li H, Cai L, Yang L
International journal of molecular sciences 2019 Dec 6;20(24)
International journal of molecular sciences 2019 Dec 6;20(24)
miR-204-5p Represses Bone Metastasis via Inactivating NF-κB Signaling in Prostate Cancer.
Wa Q, Huang S, Pan J, Tang Y, He S, Fu X, Peng X, Chen X, Yang C, Ren D, Huang Y, Liao Z, Huang S, Zou C
Molecular therapy. Nucleic acids 2019 Dec 6;18:567-579
Molecular therapy. Nucleic acids 2019 Dec 6;18:567-579
Sal B Alleviates Myocardial Ischemic Injury by Inhibiting TLR4 and the Priming Phase of NLRP3 Inflammasome.
Hu Y, Li Q, Pan Y, Xu L
Molecules (Basel, Switzerland) 2019 Dec 3;24(23)
Molecules (Basel, Switzerland) 2019 Dec 3;24(23)
Water-separated part of Chloranthus serratus alleviates lipopolysaccharide- induced RAW264.7 cell injury mainly by regulating the MAPK and Nrf2/HO-1 inflammatory pathways.
Sun S, Du Y, Yin C, Suo X, Wang R, Xia R, Zhang X
BMC complementary and alternative medicine 2019 Dec 2;19(1):343
BMC complementary and alternative medicine 2019 Dec 2;19(1):343
Protease-activated receptor 2 (PAR-2) antagonist AZ3451 as a novel therapeutic agent for osteoarthritis.
Huang X, Ni B, Xi Y, Chu X, Zhang R, You H
Aging 2019 Dec 16;11(24):12532-12545
Aging 2019 Dec 16;11(24):12532-12545
Deoxynivalenol Induces Inflammatory Injury in IPEC-J2 Cells via NF-κB Signaling Pathway.
Wang X, Zhang Y, Zhao J, Cao L, Zhu L, Huang Y, Chen X, Rahman SU, Feng S, Li Y, Wu J
Toxins 2019 Dec 16;11(12)
Toxins 2019 Dec 16;11(12)
KRAB-Zinc Finger Protein ZNF268a Deficiency Attenuates the Virus-Induced Pro-Inflammatory Response by Preventing IKK Complex Assembly.
Liu Y, Yin W, Wang J, Lei Y, Sun G, Li W, Huang Z, Guo M
Cells 2019 Dec 10;8(12)
Cells 2019 Dec 10;8(12)
Dietary resveratrol supplementation inhibits heat stress-induced high-activated innate immunity and inflammatory response in spleen of yellow-feather broilers.
He S, Yu Q, He Y, Hu R, Xia S, He J
Poultry science 2019 Dec 1;98(12):6378-6387
Poultry science 2019 Dec 1;98(12):6378-6387
Cysteinyl Leukotriene Receptor 2 is Involved in Inflammation and Neuronal Damage by Mediating Microglia M1/M2 Polarization through NF-κB Pathway.
Zhao R, Ying M, Gu S, Yin W, Li Y, Yuan H, Fang S, Li M
Neuroscience 2019 Dec 1;422:99-118
Neuroscience 2019 Dec 1;422:99-118
JLP-centrosome is essential for the microtubule-mediated nucleocytoplasmic transport induced by extracellular stimuli.
Lee CM, Aizawa K, Jiang J, Kung SKP, Jain R
Science advances 2019 Aug;5(8):eaav0318
Science advances 2019 Aug;5(8):eaav0318
Sodium Butyrate Ameliorates Intestinal Injury and Improves Survival in a Rat Model of Cecal Ligation and Puncture-Induced Sepsis.
Fu J, Li G, Wu X, Zang B
Inflammation 2019 Aug;42(4):1276-1286
Inflammation 2019 Aug;42(4):1276-1286
Inducible LGALS3BP/90K activates antiviral innate immune responses by targeting TRAF6 and TRAF3 complex.
Xu G, Xia Z, Deng F, Liu L, Wang Q, Yu Y, Wang F, Zhu C, Liu W, Cheng Z, Zhu Y, Zhou L, Zhang Y, Lu M, Liu S
PLoS pathogens 2019 Aug;15(8):e1008002
PLoS pathogens 2019 Aug;15(8):e1008002
Bilirubin alleviates alum-induced peritonitis through inactivation of NLRP3 inflammasome.
Lin Y, Wang S, Yang Z, Gao L, Zhou Z, Yu P, Wu B
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Aug;116:108973
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Aug;116:108973
Microglia Activated by Excess Cortisol Induce HMGB1 Acetylation and Neuroinflammation in the Hippocampal DG Region of Mice Following Cold Exposure.
Xu B, Lang LM, Li SZ, Guo JR, Wang JF, Yang HM, Lian S
Biomolecules 2019 Aug 30;9(9)
Biomolecules 2019 Aug 30;9(9)
NAC1 Potentiates Cellular Antiviral Signaling by Bridging MAVS and TBK1.
Xia Z, Xu G, Nie L, Liu L, Peng N, He Q, Zuo Q, Zhou Y, Cao Z, Liu S, Zhu Y
Journal of immunology (Baltimore, Md. : 1950) 2019 Aug 15;203(4):1001-1011
Journal of immunology (Baltimore, Md. : 1950) 2019 Aug 15;203(4):1001-1011
Correction: Total saponins from Rosa laevigata Michx fruit attenuates hepatic steatosis induced by high-fat diet in rats.
Dong D, Qi Y, Xu L, Yin L, Xu Y, Han X, Zhao Y, Peng J
Food & function 2019 Aug 1;10(8):5240-5241
Food & function 2019 Aug 1;10(8):5240-5241
Quercetin reduces Streptococcus suis virulence by inhibiting suilysin activity and inflammation.
Li G, Shen X, Wei Y, Si X, Deng X, Wang J
International immunopharmacology 2019 Apr;69:71-78
International immunopharmacology 2019 Apr;69:71-78
Restorative effect of modified dioscorea pills on the structure of hippocampal neurovascular unit in an animal model of chronic cerebral hypoperfusion.
Li HB
Heliyon 2019 Apr;5(4):e01567
Heliyon 2019 Apr;5(4):e01567
MiR-92a contributes to the cardiovascular disease development in diabetes mellitus through NF-κB and downstream inflammatory pathways.
Wang WY, Zheng YS, Li ZG, Cui YM, Jiang JC
European review for medical and pharmacological sciences 2019 Apr;23(7):3070-3079
European review for medical and pharmacological sciences 2019 Apr;23(7):3070-3079
Downregulation of ENDOCAN in myeloid leukemia cells inhibits proliferation and promotes apoptosis by suppressing nuclear factor‑κB activity.
Sun L, Sun C, Sun J, Yang W
Molecular medicine reports 2019 Apr;19(4):3247-3254
Molecular medicine reports 2019 Apr;19(4):3247-3254
Protective effects of ginsenoside Rk3 against chronic alcohol-induced liver injury in mice through inhibition of inflammation, oxidative stress, and apoptosis.
Qu L, Zhu Y, Liu Y, Yang H, Zhu C, Ma P, Deng J, Fan D
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2019 Apr;126:277-284
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2019 Apr;126:277-284
Activation of the MAPK signaling pathway induces upregulation of pro-apoptotic proteins in the hippocampi of cold stressed adolescent mice.
Xu B, Lian S, Guo JR, Wang JF, Zhang LP, Li SZ, Yang HM
Neuroscience letters 2019 Apr 23;699:97-102
Neuroscience letters 2019 Apr 23;699:97-102
Rosmarinic acid attenuates inflammatory responses through inhibiting HMGB1/TLR4/NF-κB signaling pathway in a mouse model of Parkinson's disease.
Lv R, Du L, Liu X, Zhou F, Zhang Z, Zhang L
Life sciences 2019 Apr 15;223:158-165
Life sciences 2019 Apr 15;223:158-165
Immunomodulatory effects of an acidic polysaccharide fraction from herbal Gynostemma pentaphyllum tea in RAW264.7 cells.
Ren D, Zhao Y, Zheng Q, Alim A, Yang X
Food & function 2019 Apr 1;10(4):2186-2197
Food & function 2019 Apr 1;10(4):2186-2197
Thioredoxin-1 Protects Spinal Cord from Demyelination Induced by Methamphetamine through Suppressing Endoplasmic Reticulum Stress and Inflammation.
Yang L, Guo Y, Huang M, Wu X, Li X, Chen G, Li Y, Bai J
Frontiers in neurology 2018;9:49
Frontiers in neurology 2018;9:49
Magnolol Alleviates Inflammatory Responses and Lipid Accumulation by AMP-Activated Protein Kinase-Dependent Peroxisome Proliferator-Activated Receptor α Activation.
Tian Y, Feng H, Han L, Wu L, Lv H, Shen B, Li Z, Zhang Q, Liu G
Frontiers in immunology 2018;9:147
Frontiers in immunology 2018;9:147
Protective Effects of Costunolide Against D-Galactosamine and Lipopolysaccharide-Induced Acute Liver Injury in Mice.
Mao J, Yi M, Wang R, Huang Y, Chen M
Frontiers in pharmacology 2018;9:1469
Frontiers in pharmacology 2018;9:1469
Necrostatin-1 Attenuates Trauma-Induced Mouse Osteoarthritis and IL-1β Induced Apoptosis via HMGB1/TLR4/SDF-1 in Primary Mouse Chondrocytes.
Liang S, Lv ZT, Zhang JM, Wang YT, Dong YH, Wang ZG, Chen K, Cheng P, Yang Q, Guo FJ, Lu WW, Zhu WT, Chen AM
Frontiers in pharmacology 2018;9:1378
Frontiers in pharmacology 2018;9:1378
Anthraquinone Emodin Inhibits Tumor Necrosis Factor Alpha-Induced Calcification of Human Aortic Valve Interstitial Cells via the NF-κB Pathway.
Xu K, Zhou T, Huang Y, Chi Q, Shi J, Zhu P, Dong N
Frontiers in pharmacology 2018;9:1328
Frontiers in pharmacology 2018;9:1328
Pretreatment with Lactobacillus reuteri F-9-35 attenuates ethanol-induced gastric injury in rats.
Sun MC, Hou PP, Wang XY, Zhao CH, Cheng BJ, Wang YL, Hao HW, Zhang TH, Ye HQ
Food & nutrition research 2018;62
Food & nutrition research 2018;62
Mesenchymal Stem Cell-Derived Exosomes Reduce A1 Astrocytes via Downregulation of Phosphorylated NFκB P65 Subunit in Spinal Cord Injury.
Wang L, Pei S, Han L, Guo B, Li Y, Duan R, Yao Y, Xue B, Chen X, Jia Y
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;50(4):1535-1559
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;50(4):1535-1559
Alpha-Lipoic Acid Protects Human Aortic Endothelial Cells Against H2O2-Induced Injury and Inhibits Atherosclerosis in Ovariectomized Low Density Lipoprotein Receptor Knock-Out Mice.
Shen D, Tian L, Shen T, Sun H, Liu P
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(6):2261-2277
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(6):2261-2277
Panax notoginseng Saponins Regulate Macrophage Polarization under Hyperglycemic Condition via NF-κB Signaling Pathway.
Zhao Y, Zheng J, Yu Y, Wang L
BioMed research international 2018;2018:9239354
BioMed research international 2018;2018:9239354
Neuroprotective Effects of dl-3-n-Butylphthalide against Doxorubicin-Induced Neuroinflammation, Oxidative Stress, Endoplasmic Reticulum Stress, and Behavioral Changes.
Liao D, Xiang D, Dang R, Xu P, Wang J, Han W, Fu Y, Yao D, Cao L, Jiang P
Oxidative medicine and cellular longevity 2018;2018:9125601
Oxidative medicine and cellular longevity 2018;2018:9125601
Electroacupuncture: A Feasible Sirt1 Promoter Which Modulates Metainflammation in Diet-Induced Obesity Rats.
Luo D, Liu L, Liang FX, Yu ZM, Chen R
Evidence-based complementary and alternative medicine : eCAM 2018;2018:5302049
Evidence-based complementary and alternative medicine : eCAM 2018;2018:5302049
Losartan Ameliorates Calcium Oxalate-Induced Elevation of Stone-Related Proteins in Renal Tubular Cells by Inhibiting NADPH Oxidase and Oxidative Stress.
Qin B, Wang Q, Lu Y, Li C, Hu H, Zhang J, Wang Y, Zhu J, Zhu Y, Xun Y, Wang S
Oxidative medicine and cellular longevity 2018;2018:1271864
Oxidative medicine and cellular longevity 2018;2018:1271864
HIV-1 Tat increases BAG3 via NF-κB signaling to induce autophagy during HIV-associated neurocognitive disorder.
Wu X, Dong H, Ye X, Zhong L, Cao T, Xu Q, Wang J, Zhang Y, Xu J, Wang W, Wei Q, Liu Y, Wang S, Shao Y, Xing H
Cell cycle (Georgetown, Tex.) 2018;17(13):1614-1623
Cell cycle (Georgetown, Tex.) 2018;17(13):1614-1623
The Nox1/Nox4 inhibitor attenuates acute lung injury induced by ischemia-reperfusion in mice.
Cui Y, Wang Y, Li G, Ma W, Zhou XS, Wang J, Liu B
PloS one 2018;13(12):e0209444
PloS one 2018;13(12):e0209444
IRAK-M Deficiency Exacerbates Ischemic Neurovascular Injuries in Experimental Stroke Mice.
Lyu C, Zhang Y, Gu M, Huang Y, Liu G, Wang C, Li M, Chen S, Pan S, Gu Y
Frontiers in cellular neuroscience 2018;12:504
Frontiers in cellular neuroscience 2018;12:504
Inhibition of Connexin 43 Hemichannels Alleviates Cerebral Ischemia/Reperfusion Injury via the TLR4 Signaling Pathway.
Chen Y, Wang L, Zhang L, Chen B, Yang L, Li X, Li Y, Yu H
Frontiers in cellular neuroscience 2018;12:372
Frontiers in cellular neuroscience 2018;12:372
Clostridium butyricum protects the epithelial barrier by maintaining tight junction protein expression and regulating microflora in a murine model of dextran sodium sulfate-induced colitis.
Li H, Gong Y, Xie Y, Sun Q, Li Y
Scandinavian journal of gastroenterology 2018 Sep;53(9):1031-1042
Scandinavian journal of gastroenterology 2018 Sep;53(9):1031-1042
Resveratrol induces apoptosis in SGC-7901 gastric cancer cells.
Wu X, Xu Y, Zhu B, Liu Q, Yao Q, Zhao G
Oncology letters 2018 Sep;16(3):2949-2956
Oncology letters 2018 Sep;16(3):2949-2956
GABAB receptor mediate hippocampal neuroinflammation in adolescent male and female mice after cold expose.
Xu B, Lian S, Li SZ, Guo JR, Wang JF, Wang D, Zhang LP, Yang HM
Brain research bulletin 2018 Sep;142:163-175
Brain research bulletin 2018 Sep;142:163-175
StAR-related lipid transfer domain 11 (STARD11)-mediated ceramide transport mediates extracellular vesicle biogenesis.
Fukushima M, Dasgupta D, Mauer AS, Kakazu E, Nakao K, Malhi H
The Journal of biological chemistry 2018 Sep 28;293(39):15277-15289
The Journal of biological chemistry 2018 Sep 28;293(39):15277-15289
Polychlorinated Biphenyl Quinones Promotes Breast Cancer Metastasis through Reactive Oxygen Species-Mediated Nuclear Factor κB-Matrix Metalloproteinase Signaling.
Wang Y, Wang Y, Liu Z, Dong W, Yang B, Xia X, Song E, Song Y
Chemical research in toxicology 2018 Sep 17;31(9):954-963
Chemical research in toxicology 2018 Sep 17;31(9):954-963
Protective roles of NRF2 signaling pathway in cobalt chloride-induced hypoxic cytotoxicity in human HaCaT keratinocytes.
Yang B, Cheng H, Wang L, Fu J, Zhang G, Guan D, Qi R, Gao X, Zhao R
Toxicology and applied pharmacology 2018 Sep 15;355:189-197
Toxicology and applied pharmacology 2018 Sep 15;355:189-197
Activation of AMPK prevents monocrotaline-induced pulmonary arterial hypertension by suppression of NF-κB-mediated autophagy activation.
Zhai C, Shi W, Feng W, Zhu Y, Wang J, Li S, Yan X, Wang Q, Zhang Q, Chai L, Li C, Liu P, Li M
Life sciences 2018 Sep 1;208:87-95
Life sciences 2018 Sep 1;208:87-95
Microcystin-leucine arginine (MC-LR) induced inflammatory response in bovine sertoli cell via TLR4/NF-kB signaling pathway.
Adegoke EO, Wang C, Machebe NS, Wang X, Wang H, Adeniran SO, Zhang H, Zheng P, Zhang G
Environmental toxicology and pharmacology 2018 Oct;63:115-126
Environmental toxicology and pharmacology 2018 Oct;63:115-126
Long non-coding RNA FTH1P3 regulated metastasis and invasion of esophageal squamous cell carcinoma through SP1/NF-kB pathway.
Yang L, Sun K, Chu J, Qu Y, Zhao X, Yin H, Ming L, Wan J, He F
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Oct;106:1570-1577
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Oct;106:1570-1577
Salvianolic Acid B-Alleviated Angiotensin II Induces Cardiac Fibrosis by Suppressing NF-κB Pathway In Vitro.
Wang C, Luo H, Xu Y, Tao L, Chang C, Shen X
Medical science monitor : international medical journal of experimental and clinical research 2018 Oct 26;24:7654-7664
Medical science monitor : international medical journal of experimental and clinical research 2018 Oct 26;24:7654-7664
Diosmetin Attenuates Akt Signaling Pathway by Modulating Nuclear Factor Kappa-Light-Chain-Enhancer of Activated B Cells (NF-κB)/Inducible Nitric Oxide Synthase (iNOS) in Streptozotocin (STZ)-Induced Diabetic Nephropathy Mice.
Jiang Y, Liu J, Zhou Z, Liu K, Liu C
Medical science monitor : international medical journal of experimental and clinical research 2018 Oct 2;24:7007-7014
Medical science monitor : international medical journal of experimental and clinical research 2018 Oct 2;24:7007-7014
REV-ERBα integrates colon clock with experimental colitis through regulation of NF-κB/NLRP3 axis.
Wang S, Lin Y, Yuan X, Li F, Guo L, Wu B
Nature communications 2018 Oct 12;9(1):4246
Nature communications 2018 Oct 12;9(1):4246
Resveratrol inhibits monocrotaline-induced pulmonary arterial remodeling by suppression of SphK1-mediated NF-κB activation.
Shi W, Zhai C, Feng W, Wang J, Zhu Y, Li S, Wang Q, Zhang Q, Yan X, Chai L, Liu P, Chen Y, Li M
Life sciences 2018 Oct 1;210:140-149
Life sciences 2018 Oct 1;210:140-149
IL-8 analogue CXCL8 (3-72) K11R/G31P, modulates LPS-induced inflammation via AKT1-NF-kβ and ERK1/2-AP-1 pathways in THP-1 monocytes.
Walana W, Wang JJ, Yabasin IB, Ntim M, Kampo S, Al-Azab M, Elkhider A, Dogkotenge Kuugbee E, Cheng JW, Gordon JR, Li F
Human immunology 2018 Nov;79(11):809-816
Human immunology 2018 Nov;79(11):809-816
HMGB1 knock-down promoting tumor cells viability and arrest pro-apoptotic proteins via Stat3/NFκB in HepG2 cells.
Alduais S, Alduais Y, Wu X, Li H, Mao J
BioFactors (Oxford, England) 2018 Nov;44(6):570-576
BioFactors (Oxford, England) 2018 Nov;44(6):570-576
Inhibition of microRNA-143-3p attenuates myocardial hypertrophy by inhibiting inflammatory response.
Yu B, Zhao Y, Zhang H, Xie D, Nie W, Shi K
Cell biology international 2018 Nov;42(11):1584-1593
Cell biology international 2018 Nov;42(11):1584-1593
(2R,3R)Dihydromyricetin inhibits osteoclastogenesis and bone loss through scavenging LPS-induced oxidative stress and NF-κB and MAPKs pathways activating.
Zhang X, Li X, Fang J, Hou X, Fang H, Guo F, Li F, Chen A, Huang S
Journal of cellular biochemistry 2018 Nov;119(11):8981-8995
Journal of cellular biochemistry 2018 Nov;119(11):8981-8995
Caffeic acid protects against IL-1β-induced inflammatory responses and cartilage degradation in articular chondrocytes.
Huang X, Xi Y, Pan Q, Mao Z, Zhang R, Ma X, You H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Nov;107:433-439
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Nov;107:433-439
Toll-like receptor 4 shRNA attenuates lipopolysaccharide-induced epithelial-mesenchymal transition of intrahepatic biliary epithelial cells in rats.
Tang S, Jiang X, Wu L, Chen S, Chen L, Jiang J, Yan P, Wang F, Tu K, Wang D, Gu J, Zhao L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Nov;107:1210-1217
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Nov;107:1210-1217
Interleukin-18 binding protein attenuates lipopolysaccharide-induced acute lung injury in mice via suppression NF-κB and activation Nrf2 pathway.
Zhang LM, Zhang J, Zhang Y, Wang L, Fei C, Yi ZW, Dong L
Biochemical and biophysical research communications 2018 Nov 2;505(3):837-842
Biochemical and biophysical research communications 2018 Nov 2;505(3):837-842
ACT001 can prevent and reverse tamoxifen resistance in human breast cancer cell lines by inhibiting NF-κB activation.
Jin XH, Jia YS, Shi YH, Li QY, Bao SQ, Lu WP, Tong ZS
Journal of cellular biochemistry 2018 Nov 18;
Journal of cellular biochemistry 2018 Nov 18;
Macrophages mediate corticotomy-accelerated orthodontic tooth movement.
Wang Y, Zhang H, Sun W, Wang S, Zhang S, Zhu L, Chen Y, Xie L, Sun Z, Yan B
Scientific reports 2018 Nov 14;8(1):16788
Scientific reports 2018 Nov 14;8(1):16788
Schisantherin A alleviated alcohol-induced liver injury by the regulation of alcohol metabolism and NF-kB pathway.
Li B, Li D, Wang Y, Meng X, Sun X, Tian J, Shi L, Ma F
Experimental animals 2018 Nov 1;67(4):451-461
Experimental animals 2018 Nov 1;67(4):451-461
IFI16 regulates HTLV-1 replication through promoting HTLV-1 RTI-induced innate immune responses.
Yang B, Song D, Liu Y, Cui Y, Lu G, Di W, Xing H, Ma L, Guo Z, Guan Y, Wang H, Wang J
FEBS letters 2018 May;592(10):1693-1704
FEBS letters 2018 May;592(10):1693-1704
DFMG attenuates the activation of macrophages induced by co‑culture with LPC‑injured HUVE‑12 cells via the TLR4/MyD88/NF‑κB signaling pathway.
Cong L, Yang S, Zhang Y, Cao J, Fu X
International journal of molecular medicine 2018 May;41(5):2619-2628
International journal of molecular medicine 2018 May;41(5):2619-2628
MicroRNA-21 Knockout Exacerbates Angiotensin II-Induced Thoracic Aortic Aneurysm and Dissection in Mice With Abnormal Transforming Growth Factor-β-SMAD3 Signaling.
Huang X, Yue Z, Wu J, Chen J, Wang S, Wu J, Ren L, Zhang A, Deng P, Wang K, Wu C, Ding X, Ye P, Xia J
Arteriosclerosis, thrombosis, and vascular biology 2018 May;38(5):1086-1101
Arteriosclerosis, thrombosis, and vascular biology 2018 May;38(5):1086-1101
Cardioprotection of CAPE-oNO2 against myocardial ischemia/reperfusion induced ROS generation via regulating the SIRT1/eNOS/NF-κB pathway in vivo and in vitro.
Li D, Wang X, Huang Q, Li S, Zhou Y, Li Z
Redox biology 2018 May;15:62-73
Redox biology 2018 May;15:62-73
Hepatoprotection of auraptene from peels of citrus fruits against thioacetamide-induced hepatic fibrosis in mice by activating farnesoid X receptor.
Gao X, Wang C, Ning C, Liu K, Wang X, Liu Z, Sun H, Ma X, Sun P, Meng Q
Food & function 2018 May 23;9(5):2684-2694
Food & function 2018 May 23;9(5):2684-2694
Hesperidin suppresses the migration and invasion of non-small cell lung cancer cells by inhibiting the SDF-1/CXCR-4 pathway.
Xia R, Xu G, Huang Y, Sheng X, Xu X, Lu H
Life sciences 2018 May 15;201:111-120
Life sciences 2018 May 15;201:111-120
Inhibition of transient receptor potential melastatin 8 alleviates airway inflammation and remodeling in a murine model of asthma with cold air stimulus.
Liu H, Liu Q, Hua L, Pan J
Acta biochimica et biophysica Sinica 2018 May 1;50(5):499-506
Acta biochimica et biophysica Sinica 2018 May 1;50(5):499-506
Oxyresveratrol prevents lipopolysaccharide/d-galactosamine-induced acute liver injury in mice.
Jia YN, Lu HP, Peng YL, Zhang BS, Gong XB, Su J, Zhou Y, Pan MH, Xu L
International immunopharmacology 2018 Mar;56:105-112
International immunopharmacology 2018 Mar;56:105-112
Nicotine-Induced Neuroprotection against Cognitive Dysfunction after Partial Hepatectomy Involves Activation of BDNF/TrkB Signaling Pathway and Inhibition of NF-κB Signaling Pathway in Aged Rats.
Wei P, Zheng Q, Liu H, Wan T, Zhou J, Li D, Zhou H, Li J, Ji F, Tang W, Li J
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2018 Mar 6;20(4):515-522
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2018 Mar 6;20(4):515-522
Src Promotes Metastasis of Human Non-Small Cell Lung Cancer Cells through Fn14-Mediated NF-κB Signaling.
Wang W, Liu F, Wang C, Wang C, Tang Y, Jiang Z
Medical science monitor : international medical journal of experimental and clinical research 2018 Mar 3;24:1282-1294
Medical science monitor : international medical journal of experimental and clinical research 2018 Mar 3;24:1282-1294
Synergistic Effects of Salvianolic Acid B and Puerarin on Cerebral Ischemia Reperfusion Injury.
Ling C, Liang J, Zhang C, Li R, Mou Q, Qin J, Li X, Wang J
Molecules (Basel, Switzerland) 2018 Mar 2;23(3)
Molecules (Basel, Switzerland) 2018 Mar 2;23(3)
Abberent expression of NOR1 protein in tumor associated macrophages contributes to the development of DEN-induced hepatocellular carcinoma.
Chen S, Zheng P, Wang W, Yi M, Chen P, Cai J, Li J, Peng Q, Ban Y, Zhou Y, Zeng Z, Li X, Xiong W, Li G, Xiang B
Journal of cellular physiology 2018 Jun;233(6):5002-5013
Journal of cellular physiology 2018 Jun;233(6):5002-5013
Butyrolactone-I from Coral-Derived Fungus Aspergillus terreus Attenuates Neuro-Inflammatory Response via Suppression of NF-κB Pathway in BV-2 Cells.
Zhang YY, Zhang Y, Yao YB, Lei XL, Qian ZJ
Marine drugs 2018 Jun 7;16(6)
Marine drugs 2018 Jun 7;16(6)
Exosomes released by hepatocarcinoma cells endow adipocytes with tumor-promoting properties.
Wang S, Xu M, Li X, Su X, Xiao X, Keating A, Zhao RC
Journal of hematology & oncology 2018 Jun 14;11(1):82
Journal of hematology & oncology 2018 Jun 14;11(1):82
Gelofusine Attenuates Tubulointerstitial Injury Induced by cRGD-Conjugated siRNA by Regulating the TLR3 Signaling Pathway.
Cen B, Liao W, Wang Z, Gao L, Wei Y, Huang W, He S, Wang W, Liu X, Pan X, Ji A
Molecular therapy. Nucleic acids 2018 Jun 1;11:300-311
Molecular therapy. Nucleic acids 2018 Jun 1;11:300-311
BST2 promotes cell proliferation, migration and induces NF-κB activation in gastric cancer.
Liu W, Cao Y, Guan Y, Zheng C
Biotechnology letters 2018 Jul;40(7):1015-1027
Biotechnology letters 2018 Jul;40(7):1015-1027
Isosteviol ameliorates diabetic cardiomyopathy in rats by inhibiting ERK and NF-κB signaling pathways.
Tang SG, Liu XY, Ye JM, Hu TT, Yang YY, Han T, Tan W
The Journal of endocrinology 2018 Jul;238(1):47-60
The Journal of endocrinology 2018 Jul;238(1):47-60
Subcutaneous administration of infliximab-attenuated silica-induced lung fibrosis.
Zhang H, Sui JN, Gao L, Guo J
International journal of occupational medicine and environmental health 2018 Jul 4;31(4):503-515
International journal of occupational medicine and environmental health 2018 Jul 4;31(4):503-515
Macrophages confer resistance to PI3K inhibitor GDC-0941 in breast cancer through the activation of NF-κB signaling.
Usman MW, Gao J, Zheng T, Rui C, Li T, Bian X, Cheng H, Liu P, Luo F
Cell death & disease 2018 Jul 24;9(8):809
Cell death & disease 2018 Jul 24;9(8):809
Prenatal cold stress: Effect on maternal hippocampus and offspring behavior in rats.
Lian S, Wang D, Xu B, Guo W, Wang L, Li W, Ji H, Wang J, Kong F, Zhen L, Li S, Zhang L, Guo J, Yang H
Behavioural brain research 2018 Jul 2;346:1-10
Behavioural brain research 2018 Jul 2;346:1-10
Tropisetron attenuates lipopolysaccharide induced neuroinflammation by inhibiting NF-κB and SP/NK1R signaling pathway.
Yu Y, Zhu W, Liang Q, Liu J, Yang X, Sun G
Journal of neuroimmunology 2018 Jul 15;320:80-86
Journal of neuroimmunology 2018 Jul 15;320:80-86
Aspirin is Involved in the Cell Cycle Arrest, Apoptosis, Cell Migration, and Invasion of Oral Squamous Cell Carcinoma.
Zhang X, Feng H, Li Z, Guo J, Li M
International journal of molecular sciences 2018 Jul 12;19(7)
International journal of molecular sciences 2018 Jul 12;19(7)
Dietary restriction delays the secretion of senescence associated secretory phenotype by reducing DNA damage response in the process of renal aging.
Wang W, Cai G, Chen X
Experimental gerontology 2018 Jul 1;107:4-10
Experimental gerontology 2018 Jul 1;107:4-10
Protective effect of dioscin against thioacetamide-induced acute liver injury via FXR/AMPK signaling pathway in vivo.
Zheng L, Yin L, Xu L, Qi Y, Li H, Xu Y, Han X, Liu K, Peng J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jan;97:481-488
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jan;97:481-488
Anticancer effect of SZC015 on pancreatic cancer via mitochondria-dependent apoptosis and the constitutive suppression of activated nuclear factor κB and STAT3 in vitro and in vivo.
Song Y, Gao L, Tang Z, Li H, Sun B, Chu P, Qaed E, Ma X, Peng J, Wang S, Hu M, Tang Z
Journal of cellular physiology 2018 Jan;234(1):777-788
Journal of cellular physiology 2018 Jan;234(1):777-788
Proteasome Inhibitor Carbobenzoxy-L-Leucyl-L-Leucyl-L-Leucinal (MG132) Enhances Therapeutic Effect of Paclitaxel on Breast Cancer by Inhibiting Nuclear Factor (NF)-κB Signaling.
Zhang Y, Yang B, Zhao J, Li X, Zhang L, Zhai Z
Medical science monitor : international medical journal of experimental and clinical research 2018 Jan 15;24:294-304
Medical science monitor : international medical journal of experimental and clinical research 2018 Jan 15;24:294-304
Hepatoprotective effects of ethyl pyruvate against CCl4-induced hepatic fibrosis via inhibition of TLR4/NF-κB signaling and up-regulation of MMPs/TIMPs ratio.
Zhang M, Hu X, Li S, Lu C, Li J, Zong Y, Qi W, Yang H
Clinics and research in hepatology and gastroenterology 2018 Feb;42(1):72-81
Clinics and research in hepatology and gastroenterology 2018 Feb;42(1):72-81
Functional Role of SUV39H1 in Human Renal Tubular Epithelial Cells Under High-glucose Ambiance.
Wang J, Yan W, Peng X, Jiang Y, He L, Peng Y, Chen X, Ye M, Zhuo H
Inflammation 2018 Feb;41(1):1-10
Inflammation 2018 Feb;41(1):1-10
Editor's Highlight: Effects of Intraperitoneal Injection of SnS2 Flowers on Mouse Testicle.
Bai D, Li Q, Xiong Y, Zhao J, Bai L, Shen P, Yuan L, Wu P
Toxicological sciences : an official journal of the Society of Toxicology 2018 Feb 1;161(2):388-400
Toxicological sciences : an official journal of the Society of Toxicology 2018 Feb 1;161(2):388-400
Protective effects of dioscin against systemic inflammatory response syndromevia adjusting TLR2/MyD88/NF‑κb signal pathway.
Zhao X, Yin L, Fang L, Xu L, Sun P, Xu M, Liu K, Peng J
International immunopharmacology 2018 Dec;65:458-469
International immunopharmacology 2018 Dec;65:458-469
Asiatic acid from Potentilla chinensis alleviates non-alcoholic fatty liver by regulating endoplasmic reticulum stress and lipid metabolism.
Wang D, Lao L, Pang X, Qiao Q, Pang L, Feng Z, Bai F, Sun X, Lin X, Wei J
International immunopharmacology 2018 Dec;65:256-267
International immunopharmacology 2018 Dec;65:256-267
Bidirectional effects of moxifloxacin on the pro‑inflammatory response in lipopolysaccharide‑stimulated mouse peritoneal macrophages.
Qiu Z, Yuan H, Li N, Yang X, Hu X, Su F, Chen B
Molecular medicine reports 2018 Dec;18(6):5399-5408
Molecular medicine reports 2018 Dec;18(6):5399-5408
CAPE-pNO2 attenuates diabetic cardiomyopathy through the NOX4/NF-κB pathway in STZ-induced diabetic mice.
Fan L, Xiao Q, Zhang L, Wang X, Huang Q, Li S, Zhao X, Li Z
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Dec;108:1640-1650
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Dec;108:1640-1650
Correlation between the expression of IL‑18 and deep venous thrombosis.
Li G, Zhou R, Zhao X, Liu R, Ye C
International journal of molecular medicine 2018 Aug;42(2):883
International journal of molecular medicine 2018 Aug;42(2):883
MEL-pep, an analog of melittin, disrupts cell membranes and reverses 5-fluorouracil resistance in human hepatocellular carcinoma cells.
Ke M, Dong J, Wang Y, Zhang J, Zhang M, Wu Z, Lv Y, Wu R
The international journal of biochemistry & cell biology 2018 Aug;101:39-48
The international journal of biochemistry & cell biology 2018 Aug;101:39-48
NOD2 promotes dopaminergic degeneration regulated by NADPH oxidase 2 in 6-hydroxydopamine model of Parkinson's disease.
Cheng L, Chen L, Wei X, Wang Y, Ren Z, Zeng S, Zhang X, Wen H, Gao C, Liu H
Journal of neuroinflammation 2018 Aug 29;15(1):243
Journal of neuroinflammation 2018 Aug 29;15(1):243
Cold atmospheric plasma conveys selectivity on triple negative breast cancer cells both in vitro and in vivo.
Xiang L, Xu X, Zhang S, Cai D, Dai X
Free radical biology & medicine 2018 Aug 20;124:205-213
Free radical biology & medicine 2018 Aug 20;124:205-213
Renal ischemia-reperfusion injury attenuated by splenic ischemic preconditioning.
Shen Y, Qiu T, Liu XH, Zhang L, Wang ZS, Zhou JQ
European review for medical and pharmacological sciences 2018 Apr;22(7):2134-2142
European review for medical and pharmacological sciences 2018 Apr;22(7):2134-2142
LPS‑induced proinflammatory cytokine expression in human airway epithelial cells and macrophages via NF‑κB, STAT3 or AP‑1 activation.
Liu X, Yin S, Chen Y, Wu Y, Zheng W, Dong H, Bai Y, Qin Y, Li J, Feng S, Zhao P
Molecular medicine reports 2018 Apr;17(4):5484-5491
Molecular medicine reports 2018 Apr;17(4):5484-5491
Bergenin, Acting as an Agonist of PPARγ, Ameliorates Experimental Colitis in Mice through Improving Expression of SIRT1, and Therefore Inhibiting NF-κB-Mediated Macrophage Activation.
Wang K, Li YF, Lv Q, Li XM, Dai Y, Wei ZF
Frontiers in pharmacology 2017;8:981
Frontiers in pharmacology 2017;8:981
Carnosic Acid Alleviates BDL-Induced Liver Fibrosis through miR-29b-3p-Mediated Inhibition of the High-Mobility Group Box 1/Toll-Like Receptor 4 Signaling Pathway in Rats.
Zhang S, Wang Z, Zhu J, Xu T, Zhao Y, Zhao H, Tang F, Li Z, Zhou J, Gao D, Tian X, Yao J
Frontiers in pharmacology 2017;8:976
Frontiers in pharmacology 2017;8:976
TET2 Protects against oxLDL-Induced HUVEC Dysfunction by Upregulating the CSE/H2S System.
Peng J, Tang ZH, Ren Z, He B, Zeng Y, Liu LS, Wang Z, Wei DH, Zheng XL, Jiang ZS
Frontiers in pharmacology 2017;8:486
Frontiers in pharmacology 2017;8:486
Protective Effects of Dioscin against Lipopolysaccharide-Induced Acute Lung Injury through Inhibition of Oxidative Stress and Inflammation.
Yao H, Sun Y, Song S, Qi Y, Tao X, Xu L, Yin L, Han X, Xu Y, Li H, Sun H, Peng J
Frontiers in pharmacology 2017;8:120
Frontiers in pharmacology 2017;8:120
Iridoids with Genipin Stem Nucleus Inhibit Lipopolysaccharide-Induced Inflammation and Oxidative Stress by Blocking the NF-κB Pathway in Polycystic Ovary Syndrome.
Zuo T, Zhu M, Xu W, Wang Z, Song H
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(5):1855-1865
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(5):1855-1865
Metformin Sensitizes Non-small Cell Lung Cancer Cells to an Epigallocatechin-3-Gallate (EGCG) Treatment by Suppressing the Nrf2/HO-1 Signaling Pathway.
Yu C, Jiao Y, Xue J, Zhang Q, Yang H, Xing L, Chen G, Wu J, Zhang S, Zhu W, Cao J
International journal of biological sciences 2017;13(12):1560-1569
International journal of biological sciences 2017;13(12):1560-1569
Collagen gel protects L929 cells from TNFα-induced death by activating NF-κB.
Wang HJ, Li MQ, Liu WW, Hayashi T, Fujisaki H, Hattori S, Tashiro SI, Onodera S, Ikejima T
Connective tissue research 2017 Sep;58(5):456-463
Connective tissue research 2017 Sep;58(5):456-463
MicroRNA-27a/b mediates endothelin-1-induced PPARγ reduction and proliferation of pulmonary artery smooth muscle cells.
Xie X, Li S, Zhu Y, Liu L, Pan Y, Wang J, Shi W, Song Y, Yang L, Gao L, Zang W, Li M
Cell and tissue research 2017 Sep;369(3):527-539
Cell and tissue research 2017 Sep;369(3):527-539
Mechanism of Lycium barbarum polysaccharides on primary cultured rat hippocampal neurons.
Zhao P, Ma NT, Chang RY, Li YX, Hao YJ, Yang WL, Zheng J, Niu Y, Sun T, Yu JQ
Cell and tissue research 2017 Sep;369(3):455-465
Cell and tissue research 2017 Sep;369(3):455-465
Anti-inflammatory activity of coptisine free base in mice through inhibition of NF-κB and MAPK signaling pathways.
Chen HB, Luo CD, Liang JL, Zhang ZB, Lin GS, Wu JZ, Li CL, Tan LH, Yang XB, Su ZR, Xie JH, Zeng HF
European journal of pharmacology 2017 Sep 15;811:222-231
European journal of pharmacology 2017 Sep 15;811:222-231
Interleukin-17A Plays the Same Role on Mice Acute Lung Injury Respectively Induced by Lipopolysaccharide and Paraquat.
Song HW, Yang C, Liu W, Liu XW, Liu Z, Gao F
Inflammation 2017 Oct;40(5):1509-1519
Inflammation 2017 Oct;40(5):1509-1519
Anti-inflammatory capacity of Lactobacillus rhamnosus GG in monophasic variant Salmonella infected piglets is correlated with impeding NLRP6-mediated host inflammatory responses.
Yu J, Zhu YH, Yang GY, Zhang W, Zhou D, Su JH, Wang JF
Veterinary microbiology 2017 Oct;210:91-100
Veterinary microbiology 2017 Oct;210:91-100
Ku70 Senses HTLV-1 DNA and Modulates HTLV-1 Replication.
Wang J, Kang L, Song D, Liu L, Yang S, Ma L, Guo Z, Ding H, Wang H, Yang B
Journal of immunology (Baltimore, Md. : 1950) 2017 Oct 1;199(7):2475-2482
Journal of immunology (Baltimore, Md. : 1950) 2017 Oct 1;199(7):2475-2482
Schisantherin A attenuates ischemia/reperfusion-induced neuronal injury in rats via regulation of TLR4 and C5aR1 signaling pathways.
Shi YW, Zhang XC, Chen C, Tang M, Wang ZW, Liang XM, Ding F, Wang CP
Brain, behavior, and immunity 2017 Nov;66:244-256
Brain, behavior, and immunity 2017 Nov;66:244-256
Hepatoprotective effect of quercetin against LPS/d-GalN induced acute liver injury in mice by inhibiting the IKK/NF-κB and MAPK signal pathways.
Peng Z, Gong X, Yang Y, Huang L, Zhang Q, Zhang P, Wan R, Zhang B
International immunopharmacology 2017 Nov;52:281-289
International immunopharmacology 2017 Nov;52:281-289
The effect of Astragaloside IV on ethanol-induced gastric mucosal injury in rats: Involvement of inflammation.
Qin S, Huang K, Fang Z, Yin J, Dai R
International immunopharmacology 2017 Nov;52:211-217
International immunopharmacology 2017 Nov;52:211-217
Lymphotoxins Promote the Progression of Human Lymphatic Malformation by Enhancing Lymphatic Endothelial Cell Proliferation.
Yang JG, Sun YF, He KF, Ren JG, Liu ZJ, Liu B, Zhang W, Zhao YF
The American journal of pathology 2017 Nov;187(11):2602-2615
The American journal of pathology 2017 Nov;187(11):2602-2615
Steroidogenic Acute Regulatory Protein (StAR) Overexpression Reduces Inflammation and Insulin Resistance in Obese Mice.
Qiu Y, Sui X, Cao S, Li X, Ning Y, Wang S, Yin L, Zhi X
Journal of cellular biochemistry 2017 Nov;118(11):3932-3942
Journal of cellular biochemistry 2017 Nov;118(11):3932-3942
Comparative study of macrophages in naked mole rats and ICR mice.
Cheng J, Yuan Z, Yang W, Xu C, Cong W, Lin L, Zhao S, Sun W, Bai X, Cui S
Oncotarget 2017 Nov 14;8(57):96924-96934
Oncotarget 2017 Nov 14;8(57):96924-96934
miR-221/222 promote cancer stem-like cell properties and tumor growth of breast cancer via targeting PTEN and sustained Akt/NF-κB/COX-2 activation.
Li B, Lu Y, Yu L, Han X, Wang H, Mao J, Shen J, Wang B, Tang J, Li C, Song B
Chemico-biological interactions 2017 Nov 1;277:33-42
Chemico-biological interactions 2017 Nov 1;277:33-42
Antioxidation, anti-inflammation and anti-apoptosis by paeonol in LPS/d-GalN-induced acute liver failure in mice.
Gong X, Yang Y, Huang L, Zhang Q, Wan RZ, Zhang P, Zhang B
International immunopharmacology 2017 May;46:124-132
International immunopharmacology 2017 May;46:124-132
6-Gingerol protects intestinal barrier from ischemia/reperfusion-induced damage via inhibition of p38 MAPK to NF-κB signalling.
Li Y, Xu B, Xu M, Chen D, Xiong Y, Lian M, Sun Y, Tang Z, Wang L, Jiang C, Lin Y
Pharmacological research 2017 May;119:137-148
Pharmacological research 2017 May;119:137-148
Diosmetin exerts anti-oxidative, anti-inflammatory and anti-apoptotic effects to protect against endotoxin-induced acute hepatic failure in mice.
Yang Y, Gong XB, Huang LG, Wang ZX, Wan RZ, Zhang P, Zhang QY, Chen Z, Zhang BS
Oncotarget 2017 May 9;8(19):30723-30733
Oncotarget 2017 May 9;8(19):30723-30733
ZNF545 suppresses human hepatocellular carcinoma growth by inhibiting NF-kB signaling.
Yang W, Yang S, Zhang M, Gao D, He T, Guo M
Genes & cancer 2017 Mar;8(3-4):528-535
Genes & cancer 2017 Mar;8(3-4):528-535
RelA/p65 inhibition prevents tendon adhesion by modulating inflammation, cell proliferation, and apoptosis.
Chen S, Jiang S, Zheng W, Tu B, Liu S, Ruan H, Fan C
Cell death & disease 2017 Mar 30;8(3):e2710
Cell death & disease 2017 Mar 30;8(3):e2710
Chemical characterization of a novel polysaccharide ASKP-1 from Artemisia sphaerocephala Krasch seed and its macrophage activation via MAPK, PI3k/Akt and NF-κB signaling pathways in RAW264.7 cells.
Ren D, Lin D, Alim A, Zheng Q, Yang X
Food & function 2017 Mar 22;8(3):1299-1312
Food & function 2017 Mar 22;8(3):1299-1312
TNF-α stimulates endothelial palmitic acid transcytosis and promotes insulin resistance.
Li W, Yang X, Zheng T, Xing S, Wu Y, Bian F, Wu G, Li Y, Li J, Bai X, Wu D, Jia X, Wang L, Zhu L, Jin S
Scientific reports 2017 Mar 17;7:44659
Scientific reports 2017 Mar 17;7:44659
Simvastatin Inhibits IL-1β-Induced Apoptosis and Extracellular Matrix Degradation by Suppressing the NF-kB and MAPK Pathways in Nucleus Pulposus Cells.
Tu J, Li W, Zhang Y, Wu X, Song Y, Kang L, Liu W, Wang K, Li S, Hua W, Yang C
Inflammation 2017 Jun;40(3):725-734
Inflammation 2017 Jun;40(3):725-734
Chronic obstructive sleep apnea promotes aortic remodeling in canines through miR-145/Smad3 signaling pathway.
Yu C, Liu Y, Sun L, Wang D, Wang Y, Zhao S, Dai H, Zhao J, Zhang S, Li M, Han Y, Lu S, Dong X, Liu G, Yu S, Li Y
Oncotarget 2017 Jun 6;8(23):37705-37716
Oncotarget 2017 Jun 6;8(23):37705-37716
p62/SQSTM1 as an oncotarget mediates cisplatin resistance through activating RIP1-NF-κB pathway in human ovarian cancer cells.
Yan XY, Zhang Y, Zhang JJ, Zhang LC, Liu YN, Wu Y, Xue YN, Lu SY, Su J, Sun LK
Cancer science 2017 Jul;108(7):1405-1413
Cancer science 2017 Jul;108(7):1405-1413
Cytoplasmic fragment of CD147 generated by regulated intramembrane proteolysis contributes to HCC by promoting autophagy.
Wu B, Cui J, Yang XM, Liu ZY, Song F, Li L, Jiang JL, Chen ZN
Cell death & disease 2017 Jul 13;8(7):e2925
Cell death & disease 2017 Jul 13;8(7):e2925
Long non-coding RNA HOXA-AS2 promotes proliferation and invasion of breast cancer by acting as a miR-520c-3p sponge.
Fang Y, Wang J, Wu F, Song Y, Zhao S, Zhang Q
Oncotarget 2017 Jul 11;8(28):46090-46103
Oncotarget 2017 Jul 11;8(28):46090-46103
Oncogenic miR-210-3p promotes prostate cancer cell EMT and bone metastasis via NF-κB signaling pathway.
Ren D, Yang Q, Dai Y, Guo W, Du H, Song L, Peng X
Molecular cancer 2017 Jul 10;16(1):117
Molecular cancer 2017 Jul 10;16(1):117
Glucocorticoid-Induced Leucine Zipper Protects the Retina From Light-Induced Retinal Degeneration by Inducing Bcl-xL in Rats.
Gu R, Tang W, Lei B, Ding X, Jiang C, Xu G
Investigative ophthalmology & visual science 2017 Jul 1;58(9):3656-3668
Investigative ophthalmology & visual science 2017 Jul 1;58(9):3656-3668
Contrast Media-Induced Renal Inflammation Is Mediated Through HMGB1 and Its Receptors in Human Tubular Cells.
Guan XF, Chen QJ, Zuo XC, Guo R, Peng XD, Wang JL, Yin WJ, Li DY
DNA and cell biology 2017 Jan;36(1):67-76
DNA and cell biology 2017 Jan;36(1):67-76
Knockdown of TREM-1 suppresses IL-1β-induced chondrocyte injury via inhibiting the NF-κB pathway.
Tang J, Dong Q
Biochemical and biophysical research communications 2017 Jan 22;482(4):1240-1245
Biochemical and biophysical research communications 2017 Jan 22;482(4):1240-1245
KRAS/NF-κB/YY1/miR-489 Signaling Axis Controls Pancreatic Cancer Metastasis.
Yuan P, He XH, Rong YF, Cao J, Li Y, Hu YP, Liu Y, Li D, Lou W, Liu MF
Cancer research 2017 Jan 1;77(1):100-111
Cancer research 2017 Jan 1;77(1):100-111
Glucocorticoid-Induced Leucine Zipper Suppresses ICAM-1 and MCP-1 Expression by Dephosphorylation of NF-κB p65 in Retinal Endothelial Cells.
Gu R, Lei B, Jiang C, Xu G
Investigative ophthalmology & visual science 2017 Jan 1;58(1):631-641
Investigative ophthalmology & visual science 2017 Jan 1;58(1):631-641
TRAIL facilitates cytokine expression and macrophage migration during hypoxia/reoxygenation via ER stress-dependent NF-κB pathway.
Jiang Y, Chen X, Fan M, Li H, Zhu W, Chen X, Cao C, Xu R, Wang Y, Ma Y
Molecular immunology 2017 Feb;82:123-136
Molecular immunology 2017 Feb;82:123-136
Multiple UBXN family members inhibit retrovirus and lentivirus production and canonical NFκΒ signaling by stabilizing IκBα.
Hu Y, O'Boyle K, Auer J, Raju S, You F, Wang P, Fikrig E, Sutton RE
PLoS pathogens 2017 Feb;13(2):e1006187
PLoS pathogens 2017 Feb;13(2):e1006187
Heparanase-driven inflammation from the AGEs-stimulated macrophages changes the functions of glomerular endothelial cells.
Xu G, Qin Q, Yang M, Qiao Z, Gu Y, Niu J
Diabetes research and clinical practice 2017 Feb;124:30-40
Diabetes research and clinical practice 2017 Feb;124:30-40
Calcitriol Ameliorates AngiotensinII-Induced Renal Injury Partly via Upregulating A20.
Zhao H, Xia Y, Gan H
Inflammation 2017 Dec;40(6):1884-1893
Inflammation 2017 Dec;40(6):1884-1893
The inflammatory responses in Cu-mediated elemental imbalance is associated with mitochondrial fission and intrinsic apoptosis in Gallus gallus heart.
Li S, Zhao H, Wang Y, Shao Y, Li J, Liu J, Xing M
Chemosphere 2017 Dec;189:489-497
Chemosphere 2017 Dec;189:489-497
Downregulation of miR-141-3p promotes bone metastasis via activating NF-κB signaling in prostate cancer.
Huang S, Wa Q, Pan J, Peng X, Ren D, Huang Y, Chen X, Tang Y
Journal of experimental & clinical cancer research : CR 2017 Dec 4;36(1):173
Journal of experimental & clinical cancer research : CR 2017 Dec 4;36(1):173
Impact of prenatal cold stress on placental physiology, inflammatory response, and apoptosis in rats.
Lian S, Guo J, Wang L, Li W, Wang J, Ji H, Kong F, Xu B, Li S, Yang H
Oncotarget 2017 Dec 29;8(70):115304-115314
Oncotarget 2017 Dec 29;8(70):115304-115314
CAPE-pNO2 ameliorated diabetic nephropathy through regulating the Akt/NF-κB/ iNOS pathway in STZ-induced diabetic mice.
Wang X, Li D, Fan L, Xiao Q, Zuo H, Li Z
Oncotarget 2017 Dec 29;8(70):114506-114525
Oncotarget 2017 Dec 29;8(70):114506-114525
The p53-inducible long noncoding RNA TRINGS protects cancer cells from necrosis under glucose starvation.
Khan MR, Xiang S, Song Z, Wu M
The EMBO journal 2017 Dec 1;36(23):3483-3500
The EMBO journal 2017 Dec 1;36(23):3483-3500
Chlorogenic acid prevents inflammatory responses in IL‑1β‑stimulated human SW‑1353 chondrocytes, a model for osteoarthritis.
Liu CC, Zhang Y, Dai BL, Ma YJ, Zhang Q, Wang Y, Yang H
Molecular medicine reports 2017 Aug;16(2):1369-1375
Molecular medicine reports 2017 Aug;16(2):1369-1375
Vascular protective effects of aqueous extracts of Tribulus terrestris on hypertensive endothelial injury.
Jiang YH, Guo JH, Wu S, Yang CH
Chinese journal of natural medicines 2017 Aug;15(8):606-614
Chinese journal of natural medicines 2017 Aug;15(8):606-614
Phosphocreatine protects endothelial cells from Methylglyoxal induced oxidative stress and apoptosis via the regulation of PI3K/Akt/eNOS and NF-κB pathway.
Chu P, Han G, Ahsan A, Sun Z, Liu S, Zhang Z, Sun B, Song Y, Lin Y, Peng J, Tang Z
Vascular pharmacology 2017 Apr;91:26-35
Vascular pharmacology 2017 Apr;91:26-35
Isoquercetin Ameliorates Cerebral Impairment in Focal Ischemia Through Anti-Oxidative, Anti-Inflammatory, and Anti-Apoptotic Effects in Primary Culture of Rat Hippocampal Neurons and Hippocampal CA1 Region of Rats.
Wang CP, Shi YW, Tang M, Zhang XC, Gu Y, Liang XM, Wang ZW, Ding F
Molecular neurobiology 2017 Apr;54(3):2126-2142
Molecular neurobiology 2017 Apr;54(3):2126-2142
MicroRNA-3178 ameliorates inflammation and gastric carcinogenesis promoted by Helicobacter pylori new toxin, Tip-α, by targeting TRAF3.
Zou M, Wang F, Jiang A, Xia A, Kong S, Gong C, Zhu M, Zhou X, Zhu J, Zhu W, Cheng W
Helicobacter 2017 Apr;22(2)
Helicobacter 2017 Apr;22(2)
Early Minocycline and Late FK506 Treatment Improves Survival and Alleviates Neuroinflammation, Neurodegeneration, and Behavioral Deficits in Prion-Infected Hamsters.
Shah SZA, Zhao D, Taglialatela G, Khan SH, Hussain T, Dong H, Lai M, Zhou X, Yang L
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2017 Apr;14(2):463-483
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2017 Apr;14(2):463-483
Targeting NF-kB signaling with polymeric hybrid micelles that co-deliver siRNA and dexamethasone for arthritis therapy.
Wang Q, Jiang H, Li Y, Chen W, Li H, Peng K, Zhang Z, Sun X
Biomaterials 2017 Apr;122:10-22
Biomaterials 2017 Apr;122:10-22
Low-intensity pulsed ultrasound (LIPUS) prevents periprosthetic inflammatory loosening through FBXL2-TRAF6 ubiquitination pathway.
Zhao X, Zhao G, Shi Z, Zhou C, Chen Y, Hu B, Yan S
Scientific reports 2017 Apr 5;7:45779
Scientific reports 2017 Apr 5;7:45779
Anti-inflammatory effect of combined tetramethylpyrazine, resveratrol and curcumin in vivo.
Chen L, Liu T, Wang Q, Liu J
BMC complementary and alternative medicine 2017 Apr 27;17(1):233
BMC complementary and alternative medicine 2017 Apr 27;17(1):233
Herpes Simplex Virus 1 UL24 Abrogates the DNA Sensing Signal Pathway by Inhibiting NF-κB Activation.
Xu H, Su C, Pearson A, Mody CH, Zheng C
Journal of virology 2017 Apr 1;91(7)
Journal of virology 2017 Apr 1;91(7)
Yin-Chen-Hao Tang Attenuates Severe Acute Pancreatitis in Rat: An Experimental Verification of In silico Network Target Prediction.
Xiang H, Wang G, Qu J, Xia S, Tao X, Qi B, Zhang Q, Shang D
Frontiers in pharmacology 2016;7:378
Frontiers in pharmacology 2016;7:378
Daphnetin Protects against Cerebral Ischemia/Reperfusion Injury in Mice via Inhibition of TLR4/NF-κB Signaling Pathway.
Liu J, Chen Q, Jian Z, Xiong X, Shao L, Jin T, Zhu X, Wang L
BioMed research international 2016;2016:2816056
BioMed research international 2016;2016:2816056
Protective effects of Astragalus polysaccharides against endothelial dysfunction in hypertrophic rats induced by isoproterenol.
Han R, Tang F, Lu M, Xu C, Hu J, Mei M, Wang H
International immunopharmacology 2016 Sep;38:306-12
International immunopharmacology 2016 Sep;38:306-12
Oral kanglaite injection (KLTI) attenuates the lung cancer-promoting effect of high-fat diet (HFD)-induced obesity.
Cao N, Ma X, Guo Z, Zheng Y, Geng S, Meng M, Du Z, Lin H, Duan Y, Du G
Oncotarget 2016 Sep 20;7(38):61093-61106
Oncotarget 2016 Sep 20;7(38):61093-61106
miR-34a and its novel target, NLRC5, are associated with HPV16 persistence.
Li J, Yu L, Shen Z, Li Y, Chen B, Wei W, Chen X, Wang Q, Tong F, Lou H, Chu M, Wei L
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2016 Oct;44:293-299
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2016 Oct;44:293-299
Downregulation of DNA-PKcs suppresses P-gp expression via inhibition of the Akt/NF-κB pathway in CD133-positive osteosarcoma MG-63 cells.
Li K, Li X, Tian J, Wang H, Pan J, Li J
Oncology reports 2016 Oct;36(4):1973-80
Oncology reports 2016 Oct;36(4):1973-80
Novel recombinant protein FlaA N/C increases tumor radiosensitivity via NF-κB signaling in murine breast cancer cells.
Xu Y, Wu D, Fan Y, Li P, Du H, Shi J, Wang D, Zhou X
Oncology letters 2016 Oct;12(4):2632-2640
Oncology letters 2016 Oct;12(4):2632-2640
Neuroprotective effects of Kaempferide-7-O-(4″-O-acetylrhamnosyl)-3-O-rutinoside on cerebral ischemia-reperfusion injury in rats.
Wang S, Xu H, Xin Y, Li M, Fu W, Wang Y, Lu Z, Yu X, Sui D
European journal of pharmacology 2016 Oct 5;788:335-342
European journal of pharmacology 2016 Oct 5;788:335-342
Dioscin attenuates gastric ischemia/reperfusion injury through the down-regulation of PKC/ERK1/2 signaling via PKCα and PKCβ2 inhibition.
Hu Y, Tao X, Han X, Xu L, Yin L, Qi Y, Zhao Y, Xu Y, Wang C, Peng J
Chemico-biological interactions 2016 Oct 25;258:234-44
Chemico-biological interactions 2016 Oct 25;258:234-44
Cleavage and polyadenylation specific factor 4 targets NF-κB/cyclooxygenase-2 signaling to promote lung cancer growth and progression.
Yi C, Wang Y, Zhang C, Xuan Y, Zhao S, Liu T, Li W, Liao Y, Feng X, Hao J, Gao Y, Yu W, Chen Y, Zhang C, Guo W, Tang B, Deng W
Cancer letters 2016 Oct 10;381(1):1-13
Cancer letters 2016 Oct 10;381(1):1-13
Charaterization and immunomodulatory activities of polysaccharide isolated from Pleurotus eryngii.
Xu D, Wang H, Zheng W, Gao Y, Wang M, Zhang Y, Gao Q
International journal of biological macromolecules 2016 Nov;92:30-36
International journal of biological macromolecules 2016 Nov;92:30-36
Anticancer effect of SZC015 on lung cancer cells through ROS-dependent apoptosis and autophagy induction mechanisms in vitro.
Sun B, Gao L, Ahsan A, Chu P, Song Y, Li H, Zhang Z, Lin Y, Peng J, Song Z, Wang S, Tang Z
International immunopharmacology 2016 Nov;40:400-409
International immunopharmacology 2016 Nov;40:400-409
Age-associated up-regulation of EGR1 promotes granulosa cell apoptosis during follicle atresia in mice through the NF-κB pathway.
Yuan S, Wen J, Cheng J, Shen W, Zhou S, Yan W, Shen L, Luo A, Wang S
Cell cycle (Georgetown, Tex.) 2016 Nov;15(21):2895-2905
Cell cycle (Georgetown, Tex.) 2016 Nov;15(21):2895-2905
Alpha-lipoic acid defends homocysteine-induced endoplasmic reticulum and oxidative stress in HAECs.
Hu H, Wang C, Jin Y, Meng Q, Liu Q, Liu K, Sun H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 May;80:63-72
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 May;80:63-72
Inhibitory effects of S-allylmercaptocysteine against benzo(a)pyrene-induced precancerous carcinogenesis in human lung cells.
Wang K, Wang Y, Qi Q, Zhang F, Zhang Y, Zhu X, Liu G, Luan Y, Zhao Z, Cai J, Cao J, Li S
International immunopharmacology 2016 May;34:37-43
International immunopharmacology 2016 May;34:37-43
Histone deacetylase inhibitor SAHA attenuates post-seizure hippocampal microglia TLR4/MYD88 signaling and inhibits TLR4 gene expression via histone acetylation.
Hu QP, Mao DA
BMC neuroscience 2016 May 18;17(1):22
BMC neuroscience 2016 May 18;17(1):22
The role of glycogen synthase kinase-3β (GSK-3β) in endometrial carcinoma: A carcinogenesis, progression, prognosis, and target therapy marker.
Chen S, Sun KX, Liu BL, Zong ZH, Zhao Y
Oncotarget 2016 May 10;7(19):27538-51
Oncotarget 2016 May 10;7(19):27538-51
The ORF3 Protein of Genotype 1 Hepatitis E Virus Suppresses TLR3-induced NF-κB Signaling via TRADD and RIP1.
He M, Wang M, Huang Y, Peng W, Zheng Z, Xia N, Xu J, Tian D
Scientific reports 2016 Jun 8;6:27597
Scientific reports 2016 Jun 8;6:27597
Human Bocavirus NS1 and NS1-70 Proteins Inhibit TNF-α-Mediated Activation of NF-κB by targeting p65.
Liu Q, Zhang Z, Zheng Z, Zheng C, Liu Y, Hu Q, Ke X, Wang H
Scientific reports 2016 Jun 22;6:28481
Scientific reports 2016 Jun 22;6:28481
DYT-40, a novel synthetic 2-styryl-5-nitroimidazole derivative, blocks malignant glioblastoma growth and invasion by inhibiting AEG-1 and NF-κB signaling pathways.
Zou M, Duan Y, Wang P, Gao R, Chen X, Ou Y, Liang M, Wang Z, Yuan Y, Wang L, Zhu H
Scientific reports 2016 Jun 2;6:27331
Scientific reports 2016 Jun 2;6:27331
Increased mitochondrial fission promotes autophagy and hepatocellular carcinoma cell survival through the ROS-modulated coordinated regulation of the NFKB and TP53 pathways.
Huang Q, Zhan L, Cao H, Li J, Lyu Y, Guo X, Zhang J, Ji L, Ren T, An J, Liu B, Nie Y, Xing J
Autophagy 2016 Jun 2;12(6):999-1014
Autophagy 2016 Jun 2;12(6):999-1014
Dioscin alleviates dimethylnitrosamine-induced acute liver injury through regulating apoptosis, oxidative stress and inflammation.
Zhang W, Yin L, Tao X, Xu L, Zheng L, Han X, Xu Y, Wang C, Peng J
Environmental toxicology and pharmacology 2016 Jul;45:193-201
Environmental toxicology and pharmacology 2016 Jul;45:193-201
Dioscin reduces lipopolysaccharide-induced inflammatory liver injury via regulating TLR4/MyD88 signal pathway.
Yao H, Hu C, Yin L, Tao X, Xu L, Qi Y, Han X, Xu Y, Zhao Y, Wang C, Peng J
International immunopharmacology 2016 Jul;36:132-141
International immunopharmacology 2016 Jul;36:132-141
The Involvement of Protease Nexin-1 (PN1) in the Pathogenesis of Intervertebral Disc (IVD) Degeneration.
Wu X, Liu W, Duan Z, Gao Y, Li S, Wang K, Song Y, Shao Z, Yang S, Yang C
Scientific reports 2016 Jul 27;6:30563
Scientific reports 2016 Jul 27;6:30563
Protective Effect of the Total Flavonoids from Rosa laevigata Michx Fruit on Renal Ischemia-Reperfusion Injury through Suppression of Oxidative Stress and Inflammation.
Zhao L, Xu L, Tao X, Han X, Yin L, Qi Y, Peng J
Molecules (Basel, Switzerland) 2016 Jul 21;21(7)
Molecules (Basel, Switzerland) 2016 Jul 21;21(7)
CD147 promotes IKK/IκB/NF-κB pathway to resist TNF-induced apoptosis in rheumatoid arthritis synovial fibroblasts.
Zhai Y, Wu B, Li J, Yao XY, Zhu P, Chen ZN
Journal of molecular medicine (Berlin, Germany) 2016 Jan;94(1):71-82
Journal of molecular medicine (Berlin, Germany) 2016 Jan;94(1):71-82
Tetrachlorobenzoquinone exhibits neurotoxicity by inducing inflammatory responses through ROS-mediated IKK/IκB/NF-κB signaling.
Fu J, Shi Q, Song X, Xia X, Su C, Liu Z, Song E, Song Y
Environmental toxicology and pharmacology 2016 Jan;41:241-50
Environmental toxicology and pharmacology 2016 Jan;41:241-50
Novel Recombinant Protein FlaA N/C Protects against Radiation Injury via NF-κB Signaling.
Xu Y, Wu D, Fan Y, Li P, Du H, Shi J, Wang D, Zhou X
Radiation research 2016 Jan;185(1):77-86
Radiation research 2016 Jan;185(1):77-86
Dendrobium officinale Kimura et Migo attenuates diabetic cardiomyopathy through inhibiting oxidative stress, inflammation and fibrosis in streptozotocin-induced mice.
Zhang Z, Zhang D, Dou M, Li Z, Zhang J, Zhao X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 Dec;84:1350-1358
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 Dec;84:1350-1358
The role of STIM1 in the Cr(vi)-induced [Ca2+]i increase and cell injury in L-02 hepatocytes.
Yi X, Zhang Y, Zhong C, Zhong X, Xiao F
Metallomics : integrated biometal science 2016 Dec 7;8(12):1273-1282
Metallomics : integrated biometal science 2016 Dec 7;8(12):1273-1282
Polysaccharides from Acanthopanax senticosus enhances intestinal integrity through inhibiting TLR4/NF-κB signaling pathways in lipopolysaccharide-challenged mice.
Han J, Liu L, Yu N, Chen J, Liu B, Yang D, Shen G
Animal science journal = Nihon chikusan Gakkaiho 2016 Aug;87(8):1011-8
Animal science journal = Nihon chikusan Gakkaiho 2016 Aug;87(8):1011-8
Salvianolic Acid B Ameliorates Cerebral Ischemia/Reperfusion Injury Through Inhibiting TLR4/MyD88 Signaling Pathway.
Wang Y, Chen G, Yu X, Li Y, Zhang L, He Z, Zhang N, Yang X, Zhao Y, Li N, Qiu H
Inflammation 2016 Aug;39(4):1503-13
Inflammation 2016 Aug;39(4):1503-13
Deacetylation of tumor-suppressor MST1 in Hippo pathway induces its degradation through HBXIP-elevated HDAC6 in promotion of breast cancer growth.
Li L, Fang R, Liu B, Shi H, Wang Y, Zhang W, Zhang X, Ye L
Oncogene 2016 Aug 4;35(31):4048-57
Oncogene 2016 Aug 4;35(31):4048-57
Gingerol Reverses the Cancer-Promoting Effect of Capsaicin by Increased TRPV1 Level in a Urethane-Induced Lung Carcinogenic Model.
Geng S, Zheng Y, Meng M, Guo Z, Cao N, Ma X, Du Z, Li J, Duan Y, Du G
Journal of agricultural and food chemistry 2016 Aug 10;64(31):6203-11
Journal of agricultural and food chemistry 2016 Aug 10;64(31):6203-11
Astragaloside IV improves the isoproterenol-induced vascular dysfunction via attenuating eNOS uncoupling-mediated oxidative stress and inhibiting ROS-NF-κB pathways.
Xu C, Tang F, Lu M, Yang J, Han R, Mei M, Hu J, Zhou M, Wang H
International immunopharmacology 2016 Apr;33:119-27
International immunopharmacology 2016 Apr;33:119-27
Long Chain Omega-3 Polyunsaturated Fatty Acid Supplementation Alleviates Doxorubicin-Induced Depressive-Like Behaviors and Neurotoxicity in Rats: Involvement of Oxidative Stress and Neuroinflammation.
Wu YQ, Dang RL, Tang MM, Cai HL, Li HD, Liao DH, He X, Cao LJ, Xue Y, Jiang P
Nutrients 2016 Apr 23;8(4):243
Nutrients 2016 Apr 23;8(4):243
Lung tumor exosomes induce a pro-inflammatory phenotype in mesenchymal stem cells via NFκB-TLR signaling pathway.
Li X, Wang S, Zhu R, Li H, Han Q, Zhao RC
Journal of hematology & oncology 2016 Apr 18;9:42
Journal of hematology & oncology 2016 Apr 18;9:42
Knee loading inhibits osteoclast lineage in a mouse model of osteoarthritis.
Li X, Yang J, Liu D, Li J, Niu K, Feng S, Yokota H, Zhang P
Scientific reports 2016 Apr 18;6:24668
Scientific reports 2016 Apr 18;6:24668
Inhibition of Hepatocyte Apoptosis: An Important Mechanism of Corn Peptides Attenuating Liver Injury Induced by Ethanol.
Ma Z, Hou T, Shi W, Liu W, He H
International journal of molecular sciences 2015 Sep 11;16(9):22062-80
International journal of molecular sciences 2015 Sep 11;16(9):22062-80
Ghrelin Attenuates Liver Fibrosis through Regulation of TGF-β1 Expression and Autophagy.
Mao Y, Zhang S, Yu F, Li H, Guo C, Fan X
International journal of molecular sciences 2015 Sep 10;16(9):21911-30
International journal of molecular sciences 2015 Sep 10;16(9):21911-30
miRNA-99b-3p functions as a potential tumor suppressor by targeting glycogen synthase kinase-3β in oral squamous cell carcinoma Tca-8113 cells.
He K, Tong D, Zhang S, Cai D, Wang L, Yang Y, Gao L, Chang S, Guo B, Song T, Li A, Huang C
International journal of oncology 2015 Oct;47(4):1528-36
International journal of oncology 2015 Oct;47(4):1528-36
Set7 facilitates hepatitis C virus replication via enzymatic activity-dependent attenuation of the IFN-related pathway.
Han T, Wan Y, Wang J, Zhao P, Yuan Y, Wang L, She Y, Broering R, Lu M, Ye L, Zhu Y
Journal of immunology (Baltimore, Md. : 1950) 2015 Mar 15;194(6):2757-68
Journal of immunology (Baltimore, Md. : 1950) 2015 Mar 15;194(6):2757-68
GRP78 is implicated in the modulation of tumor aerobic glycolysis by promoting autophagic degradation of IKKβ.
Li Z, Wang Y, Newton IP, Zhang L, Ji P, Li Z
Cellular signalling 2015 Jun;27(6):1237-45
Cellular signalling 2015 Jun;27(6):1237-45
Protective Effect of the Total Saponins from Rosa laevigata Michx Fruit against Carbon Tetrachloride-Induced Liver Fibrosis in Rats.
Dong D, Yin L, Qi Y, Xu L, Peng J
Nutrients 2015 Jun 15;7(6):4829-50
Nutrients 2015 Jun 15;7(6):4829-50
Scutellarein inhibits cancer cell metastasis in vitro and attenuates the development of fibrosarcoma in vivo.
Shi X, Chen G, Liu X, Qiu Y, Yang S, Zhang Y, Fang X, Zhang C, Liu X
International journal of molecular medicine 2015 Jan;35(1):31-8
International journal of molecular medicine 2015 Jan;35(1):31-8
Etomidate increases mortality in septic rats through inhibition of nuclear factor kappa-B rather than by causing adrenal insufficiency.
Zhang Y, Li R, Zhu J, Wang Z, Lv S, Xiong JY
The Journal of surgical research 2015 Jan;193(1):399-406
The Journal of surgical research 2015 Jan;193(1):399-406
Rhizoma Dioscoreae Nipponicae polysaccharides protect HUVECs from H2O2-induced injury by regulating PPARγ factor and the NADPH oxidase/ROS-NF-κB signal pathway.
Jin Y, Liu K, Peng J, Wang C, Kang L, Chang N, Sun H
Toxicology letters 2015 Jan 5;232(1):149-58
Toxicology letters 2015 Jan 5;232(1):149-58
Activation of the NF-κB pathway as a mechanism of alcohol enhanced progression and metastasis of human hepatocellular carcinoma.
Wang F, Yang JL, Yu KK, Xu M, Xu YZ, Chen L, Lu YM, Fang HS, Wang XY, Hu ZQ, Li FF, Kan L, Luo J, Wang SY
Molecular cancer 2015 Jan 27;14:10
Molecular cancer 2015 Jan 27;14:10
Potent effects of dioscin against obesity in mice.
Liu M, Xu L, Yin L, Qi Y, Xu Y, Han X, Zhao Y, Sun H, Yao J, Lin Y, Liu K, Peng J
Scientific reports 2015 Jan 22;5:7973
Scientific reports 2015 Jan 22;5:7973
Clonorchis sinensis ferritin heavy chain triggers free radicals and mediates inflammation signaling in human hepatic stellate cells.
Mao Q, Xie Z, Wang X, Chen W, Ren M, Shang M, Lei H, Tian Y, Li S, Liang P, Chen T, Liang C, Xu J, Li X, Huang Y, Yu X
Parasitology research 2015 Feb;114(2):659-70
Parasitology research 2015 Feb;114(2):659-70
Anti-inflammation Effects of Oxysophoridine on Cerebral Ischemia-Reperfusion Injury in Mice.
Wang YS, Li YX, Zhao P, Wang HB, Zhou R, Hao YJ, Wang J, Wang SJ, Du J, Ma L, Sun T, Yu JQ
Inflammation 2015 Dec;38(6):2259-68
Inflammation 2015 Dec;38(6):2259-68
Artificial sweetener neohesperidin dihydrochalcone showed antioxidative, anti-inflammatory and anti-apoptosis effects against paraquat-induced liver injury in mice.
Shi Q, Song X, Fu J, Su C, Xia X, Song E, Song Y
International immunopharmacology 2015 Dec;29(2):722-729
International immunopharmacology 2015 Dec;29(2):722-729
Diallyl trisulfide inhibits naphthalene-induced oxidative injury and the production of inflammatory responses in A549 cells and mice.
Zhang F, Zhang Y, Wang K, Zhu X, Lin G, Zhao Z, Li S, Cai J, Cao J
International immunopharmacology 2015 Dec;29(2):326-333
International immunopharmacology 2015 Dec;29(2):326-333
DLC-1 induces mitochondrial apoptosis and epithelial mesenchymal transition arrest in nasopharyngeal carcinoma by targeting EGFR/Akt/NF-κB pathway.
Huang W, Liu J, Feng X, Chen H, Zeng L, Huang G, Liu W, Wang L, Jia W, Chen J, Ren C
Medical oncology (Northwood, London, England) 2015 Apr;32(4):115
Medical oncology (Northwood, London, England) 2015 Apr;32(4):115
Potent effects of dioscin against liver fibrosis.
Zhang X, Han X, Yin L, Xu L, Qi Y, Xu Y, Sun H, Lin Y, Liu K, Peng J
Scientific reports 2015 Apr 8;5:9713
Scientific reports 2015 Apr 8;5:9713
Sinomenine sensitizes multidrug-resistant colon cancer cells (Caco-2) to doxorubicin by downregulation of MDR-1 expression.
Liu Z, Duan ZJ, Chang JY, Zhang ZF, Chu R, Li YL, Dai KH, Mo GQ, Chang QY
PloS one 2014;9(6):e98560
PloS one 2014;9(6):e98560
Ethyl pyruvate pretreatment attenuates concanavalin a-induced autoimmune hepatitis in mice.
Shen M, Lu J, Cheng P, Lin C, Dai W, Wang F, Wang C, Zhang Y, Chen K, Xu L, Zhou Y, Guo C
PloS one 2014;9(2):e87977
PloS one 2014;9(2):e87977
Salidroside stimulates mitochondrial biogenesis and protects against H₂O₂-induced endothelial dysfunction.
Xing S, Yang X, Li W, Bian F, Wu D, Chi J, Xu G, Zhang Y, Jin S
Oxidative medicine and cellular longevity 2014;2014:904834
Oxidative medicine and cellular longevity 2014;2014:904834
Naringin inhibits TNF-α induced oxidative stress and inflammatory response in HUVECs via Nox4/NF-κ B and PI3K/Akt pathways.
Li W, Wang C, Peng J, Liang J, Jin Y, Liu Q, Meng Q, Liu K, Sun H
Current pharmaceutical biotechnology 2014;15(12):1173-82
Current pharmaceutical biotechnology 2014;15(12):1173-82
Role of α-lipoic acid in LPS/d-GalN induced fulminant hepatic failure in mice: studies on oxidative stress, inflammation and apoptosis.
Xia X, Su C, Fu J, Zhang P, Jiang X, Xu D, Hu L, Song E, Song Y
International immunopharmacology 2014 Oct;22(2):293-302
International immunopharmacology 2014 Oct;22(2):293-302
Tetrachloro-p-benzoquinone induces hepatic oxidative damage and inflammatory response, but not apoptosis in mouse: the prevention of curcumin.
Xu D, Hu L, Su C, Xia X, Zhang P, Fu J, Wang W, Xu D, Du H, Hu Q, Song E, Song Y
Toxicology and applied pharmacology 2014 Oct 15;280(2):305-13
Toxicology and applied pharmacology 2014 Oct 15;280(2):305-13
Effects of the total saponins from Rosa laevigata Michx fruit against acetaminophen-induced liver damage in mice via induction of autophagy and suppression of inflammation and apoptosis.
Dong D, Xu L, Han X, Qi Y, Xu Y, Yin L, Liu K, Peng J
Molecules (Basel, Switzerland) 2014 May 30;19(6):7189-206
Molecules (Basel, Switzerland) 2014 May 30;19(6):7189-206
Protective effects of dioscin against alcohol-induced liver injury.
Xu T, Zheng L, Xu L, Yin L, Qi Y, Xu Y, Han X, Peng J
Archives of toxicology 2014 Mar;88(3):739-53
Archives of toxicology 2014 Mar;88(3):739-53
Fish-oil emulsion (omega-3 polyunsaturated fatty acids) attenuates acute lung injury induced by intestinal ischemia-reperfusion through Adenosine 5'-monophosphate-activated protein kinase-sirtuin1 pathway.
Jing H, Yao J, Liu X, Fan H, Zhang F, Li Z, Tian X, Zhou Y
The Journal of surgical research 2014 Mar;187(1):252-61
The Journal of surgical research 2014 Mar;187(1):252-61
A caspase-dependent pathway is involved in Wnt/β-catenin signaling promoted apoptosis in Bacillus Calmette-Guerin infected RAW264.7 macrophages.
Wu X, Deng G, Hao X, Li Y, Zeng J, Ma C, He Y, Liu X, Wang Y
International journal of molecular sciences 2014 Mar 21;15(3):5045-62
International journal of molecular sciences 2014 Mar 21;15(3):5045-62
Mulberroside A protects against ischemic impairment in primary culture of rat cortical neurons after oxygen-glucose deprivation followed by reperfusion.
Wang CP, Zhang LZ, Li GC, Shi YW, Li JL, Zhang XC, Wang ZW, Ding F, Liang XM
Journal of neuroscience research 2014 Jul;92(7):944-54
Journal of neuroscience research 2014 Jul;92(7):944-54
Herpes simplex virus 1 protein kinase US3 hyperphosphorylates p65/RelA and dampens NF-κB activation.
Wang K, Ni L, Wang S, Zheng C
Journal of virology 2014 Jul;88(14):7941-51
Journal of virology 2014 Jul;88(14):7941-51
Colistin-induced nephrotoxicity in mice involves the mitochondrial, death receptor, and endoplasmic reticulum pathways.
Dai C, Li J, Tang S, Li J, Xiao X
Antimicrobial agents and chemotherapy 2014 Jul;58(7):4075-85
Antimicrobial agents and chemotherapy 2014 Jul;58(7):4075-85
Salvianolic acid B protects against acute ethanol-induced liver injury through SIRT1-mediated deacetylation of p53 in rats.
Li M, Lu Y, Hu Y, Zhai X, Xu W, Jing H, Tian X, Lin Y, Gao D, Yao J
Toxicology letters 2014 Jul 15;228(2):67-74
Toxicology letters 2014 Jul 15;228(2):67-74
Eupolyphaga sinensis walker displays inhibition on hepatocellular carcinoma through regulating cell growth and metastasis signaling.
Zhang Y, Zhan Y, Zhang D, Dai B, Ma W, Qi J, Liu R, He L
Scientific reports 2014 Jul 1;4:5518
Scientific reports 2014 Jul 1;4:5518
Interplay between the Notch and PI3K/Akt pathways in high glucose-induced podocyte apoptosis.
Wang XM, Yao M, Liu SX, Hao J, Liu QJ, Gao F
American journal of physiology. Renal physiology 2014 Jan;306(2):F205-13
American journal of physiology. Renal physiology 2014 Jan;306(2):F205-13
Total saponins from Rosa laevigata Michx fruit attenuates hepatic steatosis induced by high-fat diet in rats.
Dong D, Qi Y, Xu L, Yin L, Xu Y, Han X, Zhao Y, Peng J
Food & function 2014 Dec;5(12):3065-3075
Food & function 2014 Dec;5(12):3065-3075
Protective effects of the total saponins from Dioscorea nipponica Makino against carbon tetrachloride-induced liver injury in mice through suppression of apoptosis and inflammation.
Yu H, Zheng L, Yin L, Xu L, Qi Y, Han X, Xu Y, Liu K, Peng J
International immunopharmacology 2014 Apr;19(2):233-44
International immunopharmacology 2014 Apr;19(2):233-44
Protective effects of neohesperidin dihydrochalcone against carbon tetrachloride-induced oxidative damage in vivo and in vitro.
Hu L, Li L, Xu D, Xia X, Pi R, Xu D, Wang W, Du H, Song E, Song Y
Chemico-biological interactions 2014 Apr 25;213:51-9
Chemico-biological interactions 2014 Apr 25;213:51-9
14-3-3ε mediates the cell fate decision-making pathways in response of hepatocellular carcinoma to Bleomycin-induced DNA damage.
Tang S, Bao H, Zhang Y, Yao J, Yang P, Chen X
PloS one 2013;8(3):e55268
PloS one 2013;8(3):e55268
Ethyl pyruvate ameliorates hepatic ischemia-reperfusion injury by inhibiting intrinsic pathway of apoptosis and autophagy.
Shen M, Lu J, Dai W, Wang F, Xu L, Chen K, He L, Cheng P, Zhang Y, Wang C, Wu D, Yang J, Zhu R, Zhang H, Zhou Y, Guo C
Mediators of inflammation 2013;2013:461536
Mediators of inflammation 2013;2013:461536
Fluoride-elicited developmental testicular toxicity in rats: roles of endoplasmic reticulum stress and inflammatory response.
Zhang S, Jiang C, Liu H, Guan Z, Zeng Q, Zhang C, Lei R, Xia T, Gao H, Yang L, Chen Y, Wu X, Zhang X, Cui Y, Yu L, Wang Z, Wang A
Toxicology and applied pharmacology 2013 Sep 1;271(2):206-15
Toxicology and applied pharmacology 2013 Sep 1;271(2):206-15
Protective effect of flavonoid-rich extract from Rosa laevigata Michx on cerebral ischemia-reperfusion injury through suppression of apoptosis and inflammation.
Zhang S, Qi Y, Xu Y, Han X, Peng J, Liu K, Sun CK
Neurochemistry international 2013 Nov;63(5):522-32
Neurochemistry international 2013 Nov;63(5):522-32
Salvianolic acid A preconditioning confers protection against concanavalin A-induced liver injury through SIRT1-mediated repression of p66shc in mice.
Xu X, Hu Y, Zhai X, Lin M, Chen Z, Tian X, Zhang F, Gao D, Ma X, Lv L, Yao J
Toxicology and applied pharmacology 2013 Nov 15;273(1):68-76
Toxicology and applied pharmacology 2013 Nov 15;273(1):68-76
Protection of the flavonoid fraction from Rosa laevigata Michx fruit against carbon tetrachloride-induced acute liver injury in mice.
Zhang S, Lu B, Han X, Xu L, Qi Y, Yin L, Xu Y, Zhao Y, Liu K, Peng J
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2013 May;55:60-9
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2013 May;55:60-9
The hepatitis B virus X protein downregulates NF-κB signaling pathways through decreasing the Notch signaling pathway in HBx-transformed L02 cells.
Luo J, Zhou H, Wang F, Xia X, Sun Q, Wang R, Cheng B
International journal of oncology 2013 May;42(5):1636-43
International journal of oncology 2013 May;42(5):1636-43
MG132-mediated inhibition of the ubiquitin-proteasome pathway ameliorates cancer cachexia.
Zhang L, Tang H, Kou Y, Li R, Zheng Y, Wang Q, Zhou X, Jin L
Journal of cancer research and clinical oncology 2013 Jul;139(7):1105-15
Journal of cancer research and clinical oncology 2013 Jul;139(7):1105-15
Herpes simplex virus 1 E3 ubiquitin ligase ICP0 protein inhibits tumor necrosis factor alpha-induced NF-κB activation by interacting with p65/RelA and p50/NF-κB1.
Zhang J, Wang K, Wang S, Zheng C
Journal of virology 2013 Dec;87(23):12935-48
Journal of virology 2013 Dec;87(23):12935-48
Isoquercetin protects cortical neurons from oxygen-glucose deprivation-reperfusion induced injury via suppression of TLR4-NF-кB signal pathway.
Wang CP, Li JL, Zhang LZ, Zhang XC, Yu S, Liang XM, Ding F, Wang ZW
Neurochemistry international 2013 Dec;63(8):741-9
Neurochemistry international 2013 Dec;63(8):741-9
Protective effects of the total saponins from Rosa laevigata Michx fruit against carbon tetrachloride-induced acute liver injury in mice.
Dong D, Zhang S, Yin L, Tang X, Xu Y, Han X, Qi Y, Peng J
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2013 Dec;62:120-30
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2013 Dec;62:120-30
Astragaloside IV attenuates inflammatory cytokines by inhibiting TLR4/NF-кB signaling pathway in isoproterenol-induced myocardial hypertrophy.
Yang J, Wang HX, Zhang YJ, Yang YH, Lu ML, Zhang J, Li ST, Zhang SP, Li G
Journal of ethnopharmacology 2013 Dec 12;150(3):1062-70
Journal of ethnopharmacology 2013 Dec 12;150(3):1062-70
Herpes simplex virus 1 DNA polymerase processivity factor UL42 inhibits TNF-α-induced NF-κB activation by interacting with p65/RelA and p50/NF-κB1.
Zhang J, Wang S, Wang K, Zheng C
Medical microbiology and immunology 2013 Aug;202(4):313-25
Medical microbiology and immunology 2013 Aug;202(4):313-25
Downregulation of nucleoporin 88 and 214 induced by oridonin may protect OCIM2 acute erythroleukemia cells from apoptosis through regulation of nucleocytoplasmic transport of NF-κB.
Yi S, Chen Y, Wen L, Yang L, Cui G
International journal of molecular medicine 2012 Oct;30(4):877-83
International journal of molecular medicine 2012 Oct;30(4):877-83
Overexpression of steroidogenic acute regulatory protein in rat aortic endothelial cells attenuates palmitic acid-induced inflammation and reduction in nitric oxide bioavailability.
Tian D, Qiu Y, Zhan Y, Li X, Zhi X, Wang X, Yin L, Ning Y
Cardiovascular diabetology 2012 Nov 21;11:144
Cardiovascular diabetology 2012 Nov 21;11:144
Nuclear factor-kappa B activity regulates brain expression of P-glycoprotein in the kainic acid-induced seizure rats.
Yu N, Di Q, Liu H, Hu Y, Jiang Y, Yan YK, Zhang YF, Zhang YD
Mediators of inflammation 2011;2011:670613
Mediators of inflammation 2011;2011:670613
Shikonin, a Chinese plant-derived naphthoquinone, induces apoptosis in hepatocellular carcinoma cells through reactive oxygen species: A potential new treatment for hepatocellular carcinoma.
Gong K, Li W
Free radical biology & medicine 2011 Dec 15;51(12):2259-71
Free radical biology & medicine 2011 Dec 15;51(12):2259-71
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 10745-1-AP(p65 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using RELA antibody 10745-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-p65 (IP:10745-1-AP, 3ug; Detection:10745-1-AP 1:1000) with HeLa cells lysate 5000ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human breast cancer using 10745-1-AP(p65 antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue
