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antibody from antibodies-online
Targeting: MTOR
FLJ44809, FRAP, FRAP1, FRAP2, RAFT1, RAPT1
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- Antigen structure
- References [5]
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- Western blot [2]
- Immunohistochemistry [2]
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- Product number
- ABIN153493 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) (pSer2448) antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified
- Reactivity
- Human, Rat
- Host
- Rabbit
- Epitope
- pSer2448
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
- Handling
- Avoid freeze-thaw cycles
Submitted references Eriocalyxin B, a novel autophagy inducer, exerts anti-tumor activity through the suppression of Akt/mTOR/p70S6K signaling pathway in breast cancer.
Proinflammatory-activated glioma cells induce a switch in microglial polarization and activation status, from a predominant M2b phenotype to a mixture of M1 and M2a/B polarized cells.
The mTOR kinase inhibitors polarize glioma-activated microglia to express a M1 phenotype.
The mTOR kinase inhibitor rapamycin decreases iNOS mRNA stability in astrocytes.
A proliferation-inducing ligand mediates follicular lymphoma B-cell proliferation and cyclin D1 expression through phosphatidylinositol 3-kinase-regulated mammalian target of rapamycin activation.
Zhou X, Yue GG, Chan AM, Tsui SK, Fung KP, Sun H, Pu J, Lau CB
Biochemical pharmacology 2017 Oct 15;142:58-70
Biochemical pharmacology 2017 Oct 15;142:58-70
Proinflammatory-activated glioma cells induce a switch in microglial polarization and activation status, from a predominant M2b phenotype to a mixture of M1 and M2a/B polarized cells.
Lisi L, Stigliano E, Lauriola L, Navarra P, Dello Russo C
ASN neuro 2014 May 8;6(3):171-83
ASN neuro 2014 May 8;6(3):171-83
The mTOR kinase inhibitors polarize glioma-activated microglia to express a M1 phenotype.
Lisi L, Laudati E, Navarra P, Dello Russo C
Journal of neuroinflammation 2014 Jul 23;11:125
Journal of neuroinflammation 2014 Jul 23;11:125
The mTOR kinase inhibitor rapamycin decreases iNOS mRNA stability in astrocytes.
Lisi L, Navarra P, Feinstein DL, Dello Russo C
Journal of neuroinflammation 2011 Jan 5;8(1):1
Journal of neuroinflammation 2011 Jan 5;8(1):1
A proliferation-inducing ligand mediates follicular lymphoma B-cell proliferation and cyclin D1 expression through phosphatidylinositol 3-kinase-regulated mammalian target of rapamycin activation.
Gupta M, Dillon SR, Ziesmer SC, Feldman AL, Witzig TE, Ansell SM, Cerhan JR, Novak AJ
Blood 2009 May 21;113(21):5206-16
Blood 2009 May 21;113(21):5206-16
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
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- IHC
- Submitted by
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