Ab107045

antibody from Aladdin Scientific Corporation

Targeting: HDAC3 HD3, KDAC3, RPD3, RPD3-2

Western blot (Data presented on provider website)

Antibody Data

Product number

Ab107045

Provider

Aladdin Scientific Corporation

Product name

HDAC3 Mouse mAb

Antibody type

Monoclonal

Description

Mouse anti Human HDAC3 Antibody, Monoclonal (3G3-H6-H10), could be used for WB and so on. Application: WB: 1/500-1/1000 Protein Function Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Probably participates in the regulation of transcription through its binding to the zinc-finger transcription factor YY1; increases YY1 repression activity. Required to repress transcription of the POU1F1 transcription factor. Acts as a molecular chaperone for shuttling phosphorylated NR2C1 to PML bodies for sumoylation.

Reactivity

Human, Mouse, Rat

Host

Mouse

Conjugate

Unconjugated

Antigen sequence

AA 216-422


Antibody clone number

3G3-H6-H10

Vial size

100μl,10μl,1ml,50μl

Concentration

2,9 mg/ml

Storage

Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.