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- Antibody Data
- Antigen structure
- References [11]
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- Validations
- Immunohistochemistry [1]
- Blocking/Neutralizing [1]
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- Product number
- AF771 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Goat Polyclonal IL-1 RI Antibody
- Antibody type
- Polyclonal
- Description
- Antigen Affinity-purified. Detects mouse IL-1 RI in direct ELISAs and Western blots. In direct ELISAs, less than 15% cross-reactivity with recombinant mouse IL-18 R and recombinant human IL-1 RI is observed.
- Reactivity
- Mouse
- Host
- Goat
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Submitted references Spleen-derived classical monocytes mediate lung ischemia-reperfusion injury through IL-1β.
Multicolor quantitative confocal imaging cytometry.
Spinal astrocytic activation contributes to mechanical allodynia in a rat model of cyclophosphamide-induced cystitis.
Neutrophils mediate blood-spinal cord barrier disruption in demyelinating neuroinflammatory diseases.
Bone marrow-derived microglia infiltrate into the paraventricular nucleus of chronic psychological stress-loaded mice.
Pericytes support neutrophil subendothelial cell crawling and breaching of venular walls in vivo.
Interleukin-1β causes long-term potentiation deficiency in a mouse model of septic encephalopathy.
Changes in melanocortin expression and inflammatory pathways in fetal offspring of nonhuman primates fed a high-fat diet.
Type 2 diabetes impairs insulin receptor substrate-2-mediated phosphatidylinositol 3-kinase activity in primary macrophages to induce a state of cytokine resistance to IL-4 in association with overexpression of suppressor of cytokine signaling-3.
Type 2 diabetes impairs insulin receptor substrate-2-mediated phosphatidylinositol 3-kinase activity in primary macrophages to induce a state of cytokine resistance to IL-4 in association with overexpression of suppressor of cytokine signaling-3.
IL-1beta induces a MyD88-dependent and ceramide-mediated activation of Src in anterior hypothalamic neurons.
Hsiao HM, Fernandez R, Tanaka S, Li W, Spahn JH, Chiu S, Akbarpour M, Ruiz-Perez D, Wu Q, Turam C, Scozzi D, Takahashi T, Luehmann HP, Puri V, Budinger GRS, Krupnick AS, Misharin AV, Lavine KJ, Liu Y, Gelman AE, Bharat A, Kreisel D
The Journal of clinical investigation 2018 Jul 2;128(7):2833-2847
The Journal of clinical investigation 2018 Jul 2;128(7):2833-2847
Multicolor quantitative confocal imaging cytometry.
Coutu DL, Kokkaliaris KD, Kunz L, Schroeder T
Nature methods 2018 Jan;15(1):39-46
Nature methods 2018 Jan;15(1):39-46
Spinal astrocytic activation contributes to mechanical allodynia in a rat model of cyclophosphamide-induced cystitis.
Liu B, Su M, Tang S, Zhou X, Zhan H, Yang F, Li W, Li T, Xie J
Molecular pain 2016;12
Molecular pain 2016;12
Neutrophils mediate blood-spinal cord barrier disruption in demyelinating neuroinflammatory diseases.
Aubé B, Lévesque SA, Paré A, Chamma É, Kébir H, Gorina R, Lécuyer MA, Alvarez JI, De Koninck Y, Engelhardt B, Prat A, Côté D, Lacroix S
Journal of immunology (Baltimore, Md. : 1950) 2014 Sep 1;193(5):2438-54
Journal of immunology (Baltimore, Md. : 1950) 2014 Sep 1;193(5):2438-54
Bone marrow-derived microglia infiltrate into the paraventricular nucleus of chronic psychological stress-loaded mice.
Ataka K, Asakawa A, Nagaishi K, Kaimoto K, Sawada A, Hayakawa Y, Tatezawa R, Inui A, Fujimiya M
PloS one 2013;8(11):e81744
PloS one 2013;8(11):e81744
Pericytes support neutrophil subendothelial cell crawling and breaching of venular walls in vivo.
Proebstl D, Voisin MB, Woodfin A, Whiteford J, D'Acquisto F, Jones GE, Rowe D, Nourshargh S
The Journal of experimental medicine 2012 Jun 4;209(6):1219-34
The Journal of experimental medicine 2012 Jun 4;209(6):1219-34
Interleukin-1β causes long-term potentiation deficiency in a mouse model of septic encephalopathy.
Imamura Y, Wang H, Matsumoto N, Muroya T, Shimazaki J, Ogura H, Shimazu T
Neuroscience 2011 Jul 28;187:63-9
Neuroscience 2011 Jul 28;187:63-9
Changes in melanocortin expression and inflammatory pathways in fetal offspring of nonhuman primates fed a high-fat diet.
Grayson BE, Levasseur PR, Williams SM, Smith MS, Marks DL, Grove KL
Endocrinology 2010 Apr;151(4):1622-32
Endocrinology 2010 Apr;151(4):1622-32
Type 2 diabetes impairs insulin receptor substrate-2-mediated phosphatidylinositol 3-kinase activity in primary macrophages to induce a state of cytokine resistance to IL-4 in association with overexpression of suppressor of cytokine signaling-3.
O'Connor JC, Sherry CL, Guest CB, Freund GG
Journal of immunology (Baltimore, Md. : 1950) 2007 Jun 1;178(11):6886-93
Journal of immunology (Baltimore, Md. : 1950) 2007 Jun 1;178(11):6886-93
Type 2 diabetes impairs insulin receptor substrate-2-mediated phosphatidylinositol 3-kinase activity in primary macrophages to induce a state of cytokine resistance to IL-4 in association with overexpression of suppressor of cytokine signaling-3.
O'Connor JC, Sherry CL, Guest CB, Freund GG
Journal of immunology (Baltimore, Md. : 1950) 2007 Jun 1;178(11):6886-93
Journal of immunology (Baltimore, Md. : 1950) 2007 Jun 1;178(11):6886-93
IL-1beta induces a MyD88-dependent and ceramide-mediated activation of Src in anterior hypothalamic neurons.
Davis CN, Tabarean I, Gaidarova S, Behrens MM, Bartfai T
Journal of neurochemistry 2006 Sep;98(5):1379-89
Journal of neurochemistry 2006 Sep;98(5):1379-89
No comments: Submit comment
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- IL-1 RI in Mouse Skin. IL-1 RI in Mouse Skin.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Cell Proliferation Induced by IL-1a/IL-1F1 and Neutral-ization by Mouse IL-1 RI Antibody. Cell Proliferation Induced by IL-1a/IL-1F1 and Neutral-ization by Mouse IL-1 RI Antibody.
