13-0079-82

antibody from Invitrogen Antibodies
Targeting: CD7 GP40, LEU-9, Tp40, TP41
Provider product page for 13-0079-82

Antibody data

Product number
13-0079-82 - Provider product page
Provider
Invitrogen Antibodies
Product name
CD7 Monoclonal Antibody (eBio124-1D1 (124-1D1)), Biotin, eBioscience™
Antibody type
Monoclonal
Antigen
Other
Description
Description: The eBio124-1D1 monoclonal antibody reacts with human CD7, also known as gp40 and Leu9. CD7, a 40 kD receptor, is a member of the immunoglobulin gene superfamily. The N-terminal amino acid sequence (aa1-107) is highly homologous to Ig kappa light chain sequence; while the carboxyl-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T lymphocytes, and T cell leukemias. It is also found on natural killer cells, a small suppopulation of normal B cells and on maligant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity, as measured by calcium flux, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3'-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation.
Conjugate
Biotin
Antibody clone number
eBio124-1D1 (124-1D1)
Concentration
0.5 mg/mL
CD7 protein structure - 13-0079-82 shown in red.