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- Antibody Data
- Antigen structure
- References [1287]
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- Product number
- 20536-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#20536-1-AP, RRID:AB_10700003
- Product name
- beta actin antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated Beta Actin antibody (Cat. #20536-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat, monkey, canine and has been validated for the following applications: FC, IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat, Canine, Simian
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 150ul
Submitted references Panax notoginseng saponins protect PC12 cells against Aβ induced injury via promoting parkin-mediated mitophagy.
Protocatechuic aldehyde prevents ischemic injury by attenuating brain microvascular endothelial cell pyroptosis via lncRNA Xist.
Hydrogen sulphide attenuates neuronal apoptosis of substantia nigra by re-establishing autophagic flux via promoting leptin signalling in a 6-hydroxydopamine rat model of Parkinson's disease.
Dihydroartemisinin attenuates osteoclast formation and bone resorption via inhibiting the NF‑κB, MAPK and NFATc1 signaling pathways and alleviates osteoarthritis.
Corilagin induces apoptosis and inhibits autophagy of HL‑60 cells by regulating miR‑451/HMGB1 axis.
Jujuboside A ameliorates high fat diet and streptozotocin induced diabetic nephropathy via suppressing oxidative stress, apoptosis, and enhancing autophagy.
Adaptation to partial urethral obstruction in healthy aging LOU rats and the role of nerve growth factor signaling pathway in the bladder.
Overexpression of sFlt-1 represses ox-LDL-induced injury of HUVECs by activating autophagy via PI3K/AKT/mTOR pathway.
Dihydroartemisinin represses oral squamous cell carcinoma progression through downregulating mitochondrial calcium uniporter.
Inhibition of CDK1 attenuates neuronal apoptosis and autophagy and confers neuroprotection after chronic spinal cord injury in vivo.
An in vitro senescence model of gingival epithelial cell induced by hydrogen peroxide treatment.
The role of regulatory T cells on the activation of astrocytes in the brain of high-fat diet mice following lead exposure.
FSH inhibits autophagy and lysosomal biogenesis to regulate protein degradation in cultured goat Sertoli cells.
In vitro and in silico anti-osteoporosis activities and underlying mechanisms of a fructan, ABW90-1, from Achyranthes bidentate.
Xiaoyao powder improves endometrial receptivity via VEGFR-2-mediated angiogenesis through the activation of the JNK and P38 signaling pathways.
125I seeds inhibit proliferation and promote apoptosis in cholangiocarcinoma cells by regulating the AGR2-mediated p38 MAPK pathway.
TiO2 nanosheets promote the transformation of vascular smooth muscle cells into foam cells in vitro and in vivo through the up-regulation of nuclear factor kappa B subunit 2.
Inhibition of Kelch-like epichlorohydrin-related protein 1 promotes the progression and drug resistance of lung adenocarcinoma.
Combination of ferulic acid, ligustrazine and tetrahydropalmatine inhibits invasion and metastasis through MMP/TIMP signaling in endometriosis.
CTRP1 Attenuates Cerebral Ischemia/Reperfusion Injury via the PERK Signaling Pathway.
Targeted Deletion of Loxl3 by Col2a1-Cre Leads to Progressive Hearing Loss.
Osteopontin N-Terminal Function in an Abdominal Aortic Aneurysm From Apolipoprotein E-Deficient Mice.
Estrogen Receptor α Mediates Doxorubicin Sensitivity in Breast Cancer Cells by Regulating E-Cadherin.
RhoA/ROCK-YAP/TAZ Axis Regulates the Fibrotic Activity in Dexamethasone-Treated Human Trabecular Meshwork Cells.
Transcriptome Differences in Pig Tracheal Epithelial Cells in Response to Pasteurella Multocida Infection.
Indoleamine-2,3-Dioxygenase Activates Wnt/β-Catenin Inducing Kidney Fibrosis after Acute Kidney Injury.
Transient Receptor Potential Melastatin 7 Promotes Vascular Adventitial Fibroblasts Phenotypic Transformation and Inflammatory Reaction Induced by Mechanical Stretching Stress via p38 MAPK/JNK Pathway.
Study on Protection of Human Umbilical Vein Endothelial Cells from Amiodarone-Induced Damage by Intermedin through Activation of Wnt/β-Catenin Signaling Pathway.
Secretagogin Mediates the Regulatory Effect of Electroacupuncture on Hypothalamic-Pituitary-Adrenal Axis Dysfunction in Surgical Trauma.
Human Tissue Kallikrein 1 Is Downregulated in Elderly Human Prostates and Possesses Potential In Vitro Antioxidative and Antifibrotic Effects in Rodent Prostates.
The Formation of Melanocyte Apoptotic Bodies in Vitiligo and the Relocation of Vitiligo Autoantigens under Oxidative Stress.
HMSC-Derived Exosome Inhibited Th2 Cell Differentiation via Regulating miR-146a-5p/SERPINB2 Pathway.
MCU That Is Transcriptionally Regulated by Nrf2 Augments Malignant Biological Behaviors in Oral Squamous Cell Carcinoma Cells.
Decreased Expression of MPC2 Contributes to Aerobic Glycolysis and Colorectal Cancer Proliferation by Activating mTOR Pathway.
Antioral Squamous Cell Carcinoma Effects of Carvacrol via Inhibiting Inflammation, Proliferation, and Migration Related to Nrf2/Keap1 Pathway.
Metformin-Induced MicroRNA-34a-3p Downregulation Alleviates Senescence in Human Dental Pulp Stem Cells by Targeting CAB39 through the AMPK/mTOR Signaling Pathway.
Anterior Gradient Protein 2 Promotes Mucosal Repair in Pediatric Ulcerative Colitis.
Protective Effects of Huangqi Shengmai Yin on Type 1 Diabetes-Induced Cardiomyopathy by Improving Myocardial Lipid Metabolism.
Exploring the Role and Mechanism of pAMPKα-Mediated Dysregulation of Brf1 and RNA Pol III Genes.
QiShenYiQi Pill Improves Myocardial Hypertrophy Caused by Pressure Overload in Rats.
Lycopene-Loaded Microemulsion Regulates Neurogenesis in Rats with Aβ-Induced Alzheimer's Disease Rats Based on the Wnt/β-catenin Pathway.
Saikosaponin D Inhibits the Proliferation and Promotes the Apoptosis of Rat Hepatic Stellate Cells by Inducing Autophagosome Formation.
Sesamin Protects against and Ameliorates Rat Intestinal Ischemia/Reperfusion Injury with Involvement of Activating Nrf2/HO-1/NQO1 Signaling Pathway.
ARHGEF3 Associated with Invasion, Metastasis, and Proliferation in Human Osteosarcoma.
Electroacupuncture Preconditioning Reduces Oxidative Stress in the Acute Phase of Cerebral Ischemia-Reperfusion in Rats by Regulating Iron Metabolism Pathways.
Curcumin Inhibits Replication of Human Parainfluenza Virus Type 3 by Affecting Viral Inclusion Body Formation.
Metformin Corrects Glucose Metabolism Reprogramming and NLRP3 Inflammasome-Induced Pyroptosis via Inhibiting the TLR4/NF-κB/PFKFB3 Signaling in Trophoblasts: Implication for a Potential Therapy of Preeclampsia.
LncRNA H19 Upregulation Participates in the Response of Glioma Cells to Radiation.
CircMETTL3, upregulated in a m6A-dependent manner, promotes breast cancer progression.
Thymoquinone Suppresses the Proliferation, Migration and Invasiveness through Regulating ROS, Autophagic Flux and miR-877-5p in Human Bladder Carcinoma Cells.
LINC00839 Regulates Proliferation, Migration, Invasion, Apoptosis and Glycolysis in Neuroblastoma Cells Through miR-338-3p/GLUT1 Axis.
Rufinamide (RUF) suppresses inflammation and maintains the integrity of the blood-brain barrier during kainic acid-induced brain damage.
p53 Promoted Ferroptosis in Ovarian Cancer Cells Treated with Human Serum Incubated-Superparamagnetic Iron Oxides.
Self-Assembled DNA Nanostructure as a Carrier for Targeted siRNA Delivery in Glioma Cells.
Geniposide from Gardenia jasminoides var. radicans Makino Attenuates Myocardial Injury in Spontaneously Hypertensive Rats via Regulating Apoptotic and Energy Metabolism Signalling Pathway.
The Ghrelin/Growth Hormone Secretagogue Receptor System Is Involved in the Rapid and Sustained Antidepressant-Like Effect of Paeoniflorin.
Gamma Radiation Induce Inflammasome Signaling and Pyroptosis in Microvascular Endothelial Cells.
Curcumin-Alleviated Osteoarthritic Progression in Rats Fed a High-Fat Diet by Inhibiting Apoptosis and Activating Autophagy via Modulation of MicroRNA-34a.
LncRNA MALAT1 promotes breast cancer progression by sponging miR101-3p to mediate mTOR/PKM2 signal transmission.
STAT5 inhibitor attenuates atherosclerosis via inhibition of inflammation: the role of STAT5 in atherosclerosis.
Novel lncRNA LINC01614 Facilitates Bladder Cancer Proliferation, Migration and Invasion Through the miR-217/RUNX2/Wnt/β-Catenin Axis.
Calcitriol Alleviates MPP+- and MPTP-Induced Parthanatos Through the VDR/PARP1 Pathway in the Model of Parkinson's Disease.
Irisin Contributes to Neuroprotection by Promoting Mitochondrial Biogenesis After Experimental Subarachnoid Hemorrhage.
Ubenimex Suppresses the Ability of Migration and Invasion in Gastric Cancer Cells by Alleviating the Activity of the CD13/NAB1/MAPK Pathway.
ARRB1 Drives Gallbladder Cancer Progression by Facilitating TAK1/MAPK Signaling Activation.
Overexpression of TC2N is associated with poor prognosis in gastric cancer.
Nogo-B receptor is required for stabilizing TGF-β type I receptor and promotes the TGF-β1-induced epithelial-to-mesenchymal transition of non-small cell lung cancer.
Punicalin Attenuates Breast Cancer-Associated Osteolysis by Inhibiting the NF-κB Signaling Pathway of Osteoclasts.
Comprehensive Analysis of the Tumor Microenvironment and Ferroptosis-Related Genes Predict Prognosis with Ovarian Cancer.
Transcriptomic Profiling Reveals the Antiapoptosis and Antioxidant Stress Effects of Fos in Ischemic Stroke.
Brd4 Regulates the Homeostasis of CD8+ T-Lymphocytes and Their Proliferation in Response to Antigen Stimulation.
Targeting Wnt Signaling in the Tumor Immune Microenvironment to Enhancing EpCAM CAR T-Cell therapy.
Internal Disulfide Bonding and Glycosylation of Interleukin-7 Protect Against Proteolytic Inactivation by Neutrophil Metalloproteinases and Serine Proteases.
DHAV-1 Blocks the Signaling Pathway Upstream of Type I Interferon by Inhibiting the Interferon Regulatory Factor 7 Protein.
Chlorogenic Acid Improves NAFLD by Regulating gut Microbiota and GLP-1.
Sinapic Acid Reduces Oxidative Stress and Pyroptosis via Inhibition of BRD4 in Alcoholic Liver Disease.
The Protective Effects of Sulforaphane on High-Fat Diet-Induced Obesity in Mice Through Browning of White Fat.
Yi-Qi-Jian-Pi Formula Suppresses RIPK1/RIPK3-Complex-Dependent Necroptosis of Hepatocytes Through ROS Signaling and Attenuates Liver Injury in Vivo and in Vitro.
Neuroprotective Effects of Oxymatrine on PI3K/Akt/mTOR Pathway After Hypoxic-Ischemic Brain Damage in Neonatal Rats.
Chronic Intermittent Hypobaric Hypoxia Decreases High Blood Pressure by Stabilizing the Vascular Renin-Angiotensin System in Spontaneously Hypertensive Rats.
Isovitexin Inhibits Ginkgolic Acids-Induced Inflammation Through Downregulating SHP2 Activation.
SNAPIN Regulates Cell Cycle Progression to Promote Pancreatic β Cell Growth.
FLI1 Induces Megakaryopoiesis Gene Expression Through WAS/WIP-Dependent and Independent Mechanisms; Implications for Wiskott-Aldrich Syndrome.
Histone demethylase JMJD3 protects against renal fibrosis by suppressing TGFβ and Notch signaling and preserving PTEN expression.
KDM6A promotes imatinib resistance through YY1-mediated transcriptional upregulation of TRKA independently of its demethylase activity in chronic myelogenous leukemia.
Suppressing Sart1 to modulate macrophage polarization by siRNA-loaded liposomes: a promising therapeutic strategy for pulmonary fibrosis.
ACSS3 represses prostate cancer progression through downregulating lipid droplet-associated protein PLIN3.
Growth hormone receptor disrupts glucose homeostasis via promoting and stabilizing retinol binding protein 4.
Bioengineering CXCR4-overexpressing cell membrane functionalized ROS-responsive nanotherapeutics for targeting cerebral ischemia-reperfusion injury.
Deciphering the autophagy regulatory network via single-cell transcriptome analysis reveals a requirement for autophagy homeostasis in spermatogenesis.
Epigenetically silenced linc00261 contributes to the metastasis of hepatocellular carcinoma via inducing the deficiency of FOXA2 transcription.
Glia Maturation Factor Beta as a Novel Biomarker and Therapeutic Target for Hepatocellular Carcinoma.
circRPS16 Promotes Proliferation and Invasion of Hepatocellular Carcinoma by Sponging miR-876-5p to Upregulate SPINK1.
Calcium Channel Protein ORAI1 Mediates TGF-β Induced Epithelial-to-Mesenchymal Transition in Colorectal Cancer Cells.
Yap1-2 Isoform Is the Primary Mediator in TGF-β1 Induced EMT in Pancreatic Cancer.
Subunit Vaccine ESAT-6:c-di-AMP Delivered by Intranasal Route Elicits Immune Responses and Protects Against Mycobacterium tuberculosis Infection.
The Anti-Inflammatory Effect and Mucosal Barrier Protection of Clostridium butyricum RH2 in Ceftriaxone-Induced Intestinal Dysbacteriosis.
PTIP Inhibits Cell Invasion in Esophageal Squamous Cell Carcinoma via Modulation of EphA2 Expression.
Toxicity evaluation of mesoporous silica particles Santa Barbara No. 15 amorphous in human umbilical vein endothelial cells: influence of particle morphology.
Remarkable inhibition effects of afatinib alone or combining with paclitaxel in esophageal squamous cell carcinoma.
Endogenous reverse transcriptase and RNase H-mediated antiviral mechanism in embryonic stem cells.
TBC1 domain family member 23 interacts with Ras-related protein Rab-11A to promote poor prognosis of non-small-cell lung cancer via β1-integrin.
Salusin‑β participates in high glucose‑induced HK‑2 cell ferroptosis in a Nrf‑2‑dependent manner.
Mitochondrial calcium uniporter promotes cell proliferation and migration in esophageal cancer.
Protein arginine methyltransferase 5 mediates THP-1-derived macrophage activation dependent on NF-κB in endometriosis.
Treadmill exercise alleviates neuronal damage by suppressing NLRP3 inflammasome and microglial activation in the MPTP mouse model of Parkinson's disease.
Magnesium-L-threonate alleviate colonic inflammation and memory impairment in chronic-plus-binge alcohol feeding mice.
Probiotic fermentation of Ganoderma lucidum fruiting body extracts promoted its immunostimulatory activity in mice with dexamethasone-induced immunosuppression.
Blockade of GITRL/GITR signaling pathway attenuates house dust mite-induced allergic asthma in mice through inhibition of MAPKs and NF-κB signaling.
A methylation-driven gene panel predicts survival in patients with colon cancer.
Aloe-emodin prevents nerve injury and neuroinflammation caused by ischemic stroke via the PI3K/AKT/mTOR and NF-κB pathway.
Microglia-derived IL-1β promoted neuronal apoptosis through ER stress-mediated signaling pathway PERK/eIF2α/ATF4/CHOP upon arsenic exposure.
Microglia jointly degrade fibrillar alpha-synuclein cargo by distribution through tunneling nanotubes.
LncRNA ZNFTR functions as an inhibitor in pancreatic cancer by modulating ATF3/ZNF24/VEGFA pathway.
3'HS1 CTCF binding site in human β-globin locus regulates fetal hemoglobin expression.
Identification of HMGCR as the anticancer target of physapubenolide against melanoma cells by in silico target prediction.
Sodium Tanshinone IIA Sulfonate Attenuates Cigarette Smoke Extract-Induced Mitochondrial Dysfunction, Oxidative Stress, and Apoptosis in Alveolar Epithelial Cells by Enhancing SIRT1 Pathway.
Nano chitosan-zinc complex improves the growth performance and antioxidant capacity of the small intestine in weaned piglets.
Different concentrations of C5a affect human dental pulp mesenchymal stem cells differentiation.
Proteomics identifies a novel role of fibrinogen-like protein 1 in Crohn's disease.
Mechanistic study of lncRNA UCA1 promoting growth and cisplatin resistance in lung adenocarcinoma.
Structural Studies of Water-Insoluble β-Glucan from Oat Bran and Its Effect on Improving Lipid Metabolism in Mice Fed High-Fat Diet.
Aged Ripe Pu-erh Tea Reduced Oxidative Stress-Mediated Inflammation in Dextran Sulfate Sodium-Induced Colitis Mice by Regulating Intestinal Microbes.
Reduced DAPK1 Expression Promotes Stem Cell-Like Characteristics of Prostate Cancer Cells by Activating ZEB1 via Hippo/YAP Signaling Pathway.
Raf1 interacts with OIP5 to participate in oxaliplatin-induced neuropathic pain.
Abnormal spatiotemporal expression pattern of progranulin and neurodevelopment impairment in VPA-induced ASD rat model.
Effect of different exercise training intensities on age-related cardiac damage in male mice.
Nintedanib Regulates GRK2 and CXCR2 to Reduce Neutrophil Recruitment in Endotoxin-Induced Lung Injury.
Betulinic acid induces autophagy-dependent apoptosis via Bmi-1/ROS/AMPK-mTOR-ULK1 axis in human bladder cancer cells.
MicroRNA-30c-5p protects against myocardial ischemia/reperfusion injury via regulation of Bach1/Nrf2.
Analysis of the microRNA and mRNA expression profile of ricin toxin-treated RAW264.7 cells reveals that miR-155-3p suppresses cell inflammation by targeting GAB2.
Resveratrol-mediated neurorestoration after cerebral ischemic injury - Sonic Hedgehog signaling pathway.
Phenotypic differences in the inner ears of CBA/CaJ and C57BL/6J mice carrying missense and single base pair deletion mutations in the Cdh23 gene.
Activation of CB2 receptor inhibits pyroptosis and subsequently ameliorates cecal ligation and puncture-induced sepsis.
Inhibition of TNFAIP1 ameliorates the oxidative stress and inflammatory injury in myocardial ischemia/reperfusion injury through modulation of Akt/GSK-3β/Nrf2 pathway.
Inhibition of ER stress attenuates kidney injury and apoptosis induced by 3-MCPD via regulating mitochondrial fission/fusion and Ca2+ homeostasis.
The long non-coding RNA PFI protects against pulmonary fibrosis by interacting with splicing regulator SRSF1.
Exosomes derived from idiopathic gingival fibroma fibroblasts regulate gingival fibroblast proliferation and apoptosis.
Sepsis induces muscle atrophy by inhibiting proliferation and promoting apoptosis via PLK1-AKT signalling.
Human umbilical cord mesenchymal stem cells ameliorate depression by regulating Jmjd3 and microglia polarization in myocardial infarction mice.
Dihydroartemisinin suppresses proliferation, migration, the Wnt/β-catenin pathway and EMT via TNKS in gastric cancer.
The role of alcohol dehydrogenase 1C in regulating inflammatory responses in ulcerative colitis.
Integrating systematic pharmacology-based strategy and experimental validation to explore the synergistic pharmacological mechanisms of Guanxin V in treating ventricular remodeling.
Myosin 1f-mediated activation of microglia contributes to the photoreceptor degeneration in a mouse model of retinal detachment.
Ferrostatin-1 alleviated TNBS induced colitis via the inhibition of ferroptosis.
EphA2 inhibits SRA01/04 cells apoptosis by suppressing autophagy via activating PI3K/Akt/mTOR pathway.
UM-6 induces autophagy and apoptosis via the Hippo-YAP signaling pathway in cervical cancer.
ZEB1 represses biogenesis of circ-DOCK5 to facilitate metastasis in esophageal squamous cell carcinoma via a positive feedback loop with TGF-β.
RCAN1.4 attenuates renal fibrosis through inhibiting calcineurin-mediated nuclear translocation of NFAT2.
Subtractive CRISPR screen identifies the ATG16L1/vacuolar ATPase axis as required for non-canonical LC3 lipidation.
STING-mediated inflammation contributes to Gao binge ethanol feeding model.
Hypoxic tubular epithelial cells regulate the angiogenesis of HMEC-1 cells via mediation of Rab7/MMP-2 axis.
Berberine Inhibits MDA-MB-231 Cells as an Agonist of G Protein-Coupled Estrogen Receptor 1.
Fructooligosaccharide supplementation alleviated the pathological immune response and prevented the impairment of intestinal barrier in DSS-induced acute colitis mice.
Gut microbiota-dependent catabolites of tryptophan play a predominant role in the protective effects of turmeric polysaccharides against DSS-induced ulcerative colitis.
SMAD2 regulates testicular development and testosterone synthesis in Hu sheep.
METTL3 improves cardiomyocyte proliferation upon myocardial infarction via upregulating miR-17-3p in a DGCR8-dependent manner.
Chorionic villus-derived mesenchymal stem cell-mediated autophagy promotes the proliferation and invasiveness of trophoblasts under hypoxia by activating the JAK2/STAT3 signalling pathway.
Methamphetamine mediates apoptosis of vascular smooth muscle cells via the chop-related endoplasmic reticulum stress pathway.
Exercise Intervention Mitigates Pathological Liver Changes in NAFLD Zebrafish by Activating SIRT1/AMPK/NRF2 Signaling.
Effects of cannabinoid (CBD) on blood brain barrier permeability after brain injury in rats.
Melatonin alleviated oxidative stress induced by energy restriction on sheep Leydig cells through Sirt1/Sod2 pathway.
Vitamin A and retinoic acid accelerate the attenuation of intestinal adaptability upon feeding induced by high-fat diet in mice.
Downregulated fat mass and obesity-associated protein inhibits bone resorption and osteoclastogenesis by nuclear factor-kappa B inactivation.
Ginsenoside Rg1 attenuates mechanical stress-induced cardiac injury via calcium sensing receptor-related pathway.
Nicotinamide improves NAD+ levels to protect against acetaminophen-induced acute liver injury in mice.
Loss of PHLDA1 has a protective role in OGD/R-injured neurons via regulation of the GSK-3β/Nrf2 pathway.
PHLDA3 inhibition protects against myocardial ischemia/reperfusion injury by alleviating oxidative stress and inflammatory response via the Akt/Nrf2 axis.
Ferroptosis is involved in the anti-tumor effect of lycorine in renal cell carcinoma cells.
Maiwei Yangfei decoction prevents bleomycin-induced pulmonary fibrosis in mice.
Th17/IL-17 induces endothelial cell senescence via activation of NF-κB/p53/Rb signaling pathway.
Starvation induced autophagy promotes the progression of bladder cancer by LDHA mediated metabolic reprogramming.
Dual Hyaluronic Acid and Folic Acid Targeting pH-Sensitive Multifunctional 2DG@DCA@MgO-Nano-Core-Shell-Radiosensitizer for Breast Cancer Therapy.
Eurycomanol alleviates hyperuricemia by promoting uric acid excretion and reducing purine synthesis.
Isoliquiritigenin-mediated miR-23a-3p inhibition activates PGC-1α to alleviate alcoholic liver injury.
CircCRIM1 promotes ovarian cancer progression by working as ceRNAs of CRIM1 and targeting miR-383-5p/ZEB2 axis.
miR-23a/b-3p promotes hepatic lipid accumulation by regulating Srebp-1c and Fas.
Activation of RIPK2-mediated NOD1 signaling promotes proliferation and invasion of ovarian cancer cells via NF-κB pathway.
Tβ4 ameliorates oxidative damage and apoptosis through ERK/MAPK and 5-HT1A signaling pathway in Aβ insulted SH-SY5Y cells.
Protection of CAPE-pNO2 Against Chronic Myocardial Ischemia by the TGF-Β1/Galectin-3 Pathway In Vivo and In Vitro.
Molecular imaging and treatment of PSMA-positive prostate cancer with 99mTc radiolabeled aptamer-siRNA chimeras.
A novel regulatory mechanism of geniposide for improving glucose homeostasis mediated by circulating RBP4.
NLRP3 Inflammasome Activation Enhances ADK Expression to Accelerate Epilepsy in Mice.
Verapamil ameliorates proximal tubular epithelial cells apoptosis and fibrosis in diabetic kidney.
Programmed cell death 5 improves skeletal muscle insulin resistance by inhibiting IRS-1 ubiquitination through stabilization of MDM2.
TM9SF4 is a novel regulator in lineage commitment of bone marrow mesenchymal stem cells to either osteoblasts or adipocytes.
AP39 ameliorates high fat diet-induced liver injury in young rats via alleviation of oxidative stress and mitochondrial impairment.
Down-regulation of EPB41L4A-AS1 mediated the brain aging and neurodegenerative diseases via damaging synthesis of NAD+ and ATP.
TRIM15 promotes the invasion and metastasis of pancreatic cancer cells by mediating APOA1 ubiquitination and degradation.
UFL1 regulates milk protein and fat synthesis-related gene expression of bovine mammary epithelial cells probably via the mTOR signaling pathway.
Lipoxin A4 protects against paraquat‑induced acute lung injury by inhibiting the TLR4/MyD88‑mediated activation of the NF‑κB and PI3K/AKT pathways.
33-kDa ANXA3 isoform contributes to hepatocarcinogenesis via modulating ERK, PI3K/Akt-HIF and intrinsic apoptosis pathways.
GDF11 prevents the formation of thoracic aortic dissection in mice: Promotion of contractile transition of aortic SMCs.
Extracellular DJ-1 induces sterile inflammation in the ischemic brain.
Ubash3b promotes TPA-mediated suppression of leukemogenesis through accelerated downregulation of PKCδ protein.
MicroRNA-628-5p Facilitates Enterovirus 71 Infection by Suppressing TRAF3 Signaling.
Zinc-α2-glycoprotein relieved seizure-Induced neuronal glucose uptake impairment via insulin-like growth factor 1 receptor-regulated glucose transporter 3 expression.
Danthron ameliorates obesity and MAFLD through activating the interplay between PPARα/RXRα heterodimer and adiponectin receptor 2.
Human Cytomegalovirus Uses a Host Stress Response To Balance the Elongation of Saturated/Monounsaturated and Polyunsaturated Very-Long-Chain Fatty Acids.
Mechanistic insights into the anti-depressant effect of emodin: an integrated systems pharmacology study and experimental validation.
PET-CT and RNA sequencing reveal novel targets for acupuncture-induced lowering of blood pressure in spontaneously hypertensive rats.
Induced Pluripotent Stem Cell-Derived Conditioned Medium Promotes Endogenous Leukemia Inhibitory Factor to Attenuate Endotoxin-Induced Acute Lung Injury.
HMGB1 downregulation in retinal pigment epithelial cells protects against diabetic retinopathy through the autophagy-lysosome pathway.
The novel prognostic risk factor STC2 can regulate the occurrence and progression of osteosarcoma via the glycolytic pathway.
Essential Role of CRIM1 on Endometrial Receptivity in Goat.
Differentially expressed genes induced by β-caryophyllene in a rat model of cerebral ischemia-reperfusion injury.
Protective effect of recombinant Lactobacillus plantarum against H2O2-induced oxidative stress in HUVEC cells.
The HDAC and PI3K dual inhibitor CUDC-907 synergistically enhances the antileukemic activity of venetoclax in preclinical models of acute myeloid leukemia.
Glucagon-like peptide-1 (GLP-1) improved diabetic lung fibrosis via AMPK and microRNA-27a (miR-27a).
Angiotensin II-mediated improvement of renal mitochondrial function via the AMPK/PGC-1α/NRF-2 pathway is superior to norepinephrine in a rat model of septic shock associated with acute renal injury.
Low expression of BTN3A3 indicates poor prognosis and promotes cell proliferation, migration and invasion in non-small cell lung cancer.
Protein kinase D participates in cardiomyocyte hypertrophy by regulating extracellular signal-regulated and myocyte enhancer factor 2D.
The novel ALK inhibitor ZX-29 induces apoptosis through inhibiting ALK and inducing ROS-mediated endoplasmic reticulum stress in Karpas299 cells.
Effects of photoperiod on morphology and function in testis and epididymis of Cricetulus barabensis.
Resveratrol induces human colorectal cancer cell apoptosis by activating the mitochondrial pathway via increasing reactive oxygen species.
Curcumin suppresses colorectal tumorigenesis via the Wnt/β-catenin signaling pathway by downregulating Axin2.
MALAT1 sponges miR-26a and miR-26b to regulate endothelial cell angiogenesis via PFKFB3-driven glycolysis in early-onset preeclampsia.
TDP-43 and PINK1 mediate CHCHD10S59L mutation-induced defects in Drosophila and in vitro.
The combination of G-CSF and AMD3100 mobilizes bone marrow-derived stem cells to protect against cisplatin-induced acute kidney injury in mice.
GR/NF-κB signaling pathway regulates hippocampal inflammatory responses in diabetic rats with chronic unpredictable mild stress.
Exposure to Melamine cyanuric acid in adolescent mice caused emotional disorder and behavioral disorder.
Identification and functional analysis of senescence-associated secretory phenotype of premature senescent hepatocytes induced by hexavalent chromium.
Overexpression of Annexin A2 promotes proliferation by forming a Glypican 1/c-Myc positive feedback loop: prognostic significance in human glioma.
Dietary seaweed-derived polysaccharides improve growth performance of weaned pigs through maintaining intestinal barrier function and modulating gut microbial populations.
Dihydroxyeicosatrienoic Acid, a Metabolite of Epoxyeicosatrienoic Acids Upregulates Endothelial Nitric Oxide Synthase Expression Through Transcription: Mechanism of Vascular Endothelial Function Protection.
CLIC1 Inhibition Protects Against Cellular Senescence and Endothelial Dysfunction Via the Nrf2/HO-1 Pathway.
Prenatal High-Sucrose Diet Induced Vascular Dysfunction in Thoracic Artery of Fetal Offspring.
Targeting the p300/NONO axis sensitizes melanoma cells to BRAF inhibitors.
Interleukin-1 induces receptor activator of nuclear factor-κB ligand-independent osteoclast differentiation in RAW264.7 cells.
The Role of Nrf2 on the Cognitive Dysfunction of High-fat Diet Mice Following Lead Exposure.
Isolation, characterization and transcriptome analysis of porcine deltacoronavirus strain HNZK-02 from Henan Province, China.
Melatonin inhibits lipid accumulation to repress prostate cancer progression by mediating the epigenetic modification of CES1.
Hydrogen sulfide alleviates apoptosis and autophagy induced by beryllium sulfate in 16HBE cells.
Endoplasmic reticulum stress manipulates autophagic response that antagonizes polybrominated diphenyl ethers quinone induced cytotoxicity in microglial BV2 cells.
LINC00511 drives invasive behavior in hepatocellular carcinoma by regulating exosome secretion and invadopodia formation.
YTHDF1 promotes hepatocellular carcinoma progression via activating PI3K/AKT/mTOR signaling pathway and inducing epithelial-mesenchymal transition.
A metabolic data-driven systems pharmacology strategy for decoding and validating the mechanism of Compound Kushen Injection against HCC.
Hsa_circ_0008234 facilitates proliferation of cutaneous squamous cell carcinoma through targeting miR-127-5p to regulate ADCY7.
Antiviral effects of ergosterol peroxide in a pig model of porcine deltacoronavirus (PDCoV) infection involves modulation of apoptosis and tight junction in the small intestine.
Effects of total flavonoids from Eucommia ulmoides Oliv. leaves on polycystic ovary syndrome with insulin resistance model rats induced by letrozole combined with a high-fat diet.
CENPE contributes to pulmonary vascular remodeling in pulmonary hypertension.
Insulin injections inhibits PTZ-induced mitochondrial dysfunction, oxidative stress and neurological deficits via the SIRT1/PGC-1α/SIRT3 pathway.
Diosmetin ameliorate type 2 diabetic mellitus by up-regulating Corynebacterium glutamicum to regulate IRS/PI3K/AKT-mediated glucose metabolism disorder in KK-Ay mice.
PI3K/AKT pathway mediates the antidepressant- and anxiolytic-like roles of hydrogen sulfide in streptozotocin-induced diabetic rats via promoting hippocampal neurogenesis.
Cathepsin K deficiency promotes alveolar bone regeneration by promoting jaw bone marrow mesenchymal stem cells proliferation and differentiation via glycolysis pathway.
HORMAD1 promotes docetaxel resistance in triple negative breast cancer by enhancing DNA damage tolerance.
Hypoxic acclimation improves cardiac redox homeostasis and protects heart against ischemia-reperfusion injury through upregulation of O-GlcNAcylation.
The SESAME complex regulates cell senescence through the generation of acetyl-CoA.
Advanced maternal age causes premature placental senescence and malformation via dysregulated α-Klotho expression in trophoblasts.
SPOP negatively regulates Toll-like receptor-induced inflammation by disrupting MyD88 self-association.
Medioresinol as a novel PGC-1α activator prevents pyroptosis of endothelial cells in ischemic stroke through PPARα-GOT1 axis.
Resveratrol attenuates manganese-induced oxidative stress and neuroinflammation through SIRT1 signaling in mice.
Shenmai injection improves doxorubicin cardiotoxicity via miR-30a/Beclin 1.
Upregulation of RNA cap methyltransferase RNMT drives ribosome biogenesis during T cell activation.
Anoctamin 5 promotes osteosarcoma development by increasing degradation of Nel-like proteins 1 and 2.
Giardia duodenalis extracellular vesicles regulate the proinflammatory immune response in mouse macrophages in vitro via the MAPK, AKT and NF-κB pathways.
miR-126 Controls the Apoptosis and Proliferation of Immature Porcine Sertoli Cells by Targeting the PIK3R2 Gene through the PI3K/AKT Signaling Pathway.
Tumor protein D52 is upregulated in oral squamous carcinoma cells under hypoxia in a hypoxia-inducible-factor-independent manner and is involved in cell death resistance.
A novel chemical inhibitor suppresses breast cancer cell growth and metastasis through inhibiting HPIP oncoprotein.
Zinc Alleviates Arsenic-Induced Inflammation and Apoptosis in the Head Kidney of Common Carp by Inhibiting Oxidative Stress and Endoplasmic Reticulum Stress.
UHRF2 commissions the completion of DNA demethylation through allosteric activation by 5hmC and K33-linked ubiquitination of XRCC1.
A clinically acceptable strategy for sensitizing anti-PD-1 treatment by hypoxia relief.
Neuroinflammation induces anxiety- and depressive-like behavior by modulating neuronal plasticity in the basolateral amygdala.
Limonin ameliorates dextran sulfate sodium-induced chronic colitis in mice by inhibiting PERK-ATF4-CHOP pathway of ER stress and NF-κB signaling.
Sunitinib malate inhibits intestinal tumor development in male ApcMin/+ mice by down-regulating inflammation-related factors with suppressing β-cateinin/c-Myc pathway and re-balancing Bcl-6 and Caspase-3.
Astragaloside IV inhibits cell proliferation and metastasis of breast cancer via promoting the long noncoding RNA TRHDE-AS1.
A novel peptide relieves endothelial cell dysfunction in preeclampsia by regulating the PI3K/mTOR/HIF1α pathway.
MSH6 Aggravates the Hypoxic Microenvironment via Regulating HIF1A to Promote the Metastasis of Glioblastoma Multiforme.
Mefunidone ameliorates diabetic kidney disease in STZ and db/db mice.
Evaluation of piggyBac-mediated anti-CD19 CAR-T cells after ex vivo expansion with aAPCs or magnetic beads.
Carbohydrate response element-binding protein regulates lipid metabolism via mTOR complex1 in diabetic nephropathy.
Bone marrow stem cells therapy alleviates vascular injury in a chronic obstructive pulmonary disease‑obstructive sleep apnea overlap syndrome rat model.
Induction of autophagy by Beclin-1 in granulosa cells contributes to follicular progesterone elevation in ovarian endometriosis.
Protective effect of naringenin against cadmium-induced testicular toxicity in male SD rats.
The cGAS-STING signaling pathway contributes to the inflammatory response and autophagy in Aspergillus fumigatus keratitis.
EPZ015666, a selective protein arginine methyltransferase 5 (PRMT5) inhibitor with an antitumour effect in retinoblastoma.
IKKβ activation promotes amphisome formation and extracellular vesicle secretion in tumor cells.
Trichostatin A increases BDNF protein expression by improving XBP-1s/ATF6/GRP78 axis in Schwann cells of diabetic peripheral neuropathy.
Hypoxia-induced FOXO4/LDHA axis modulates gastric cancer cell glycolysis and progression.
A Cas9-transcription factor fusion protein enhances homology-directed repair efficiency.
Huaier Inhibits Proliferation, Migration, and Invasion of Cutaneous Squamous Cell Carcinoma Cells by Inhibiting the Methylation Levels of CDKN2A and TP53.
ING5 Inhibits Migration and Invasion of Esophageal Cancer Cells by Downregulating the IL-6/CXCL12 Signaling Pathway.
Obacunone Attenuates Liver Fibrosis with Enhancing Anti-Oxidant Effects of GPx-4 and Inhibition of EMT.
TRIM21-regulated Annexin A2 plasma membrane trafficking facilitates osteosarcoma cell differentiation through the TFEB-mediated autophagy.
Nrf2 overexpression increases risk of high tumor mutation burden in acute myeloid leukemia by inhibiting MSH2.
Sterol and oxysterol synthases near the ciliary base activate the Hedgehog pathway.
Autophagy impairment as a key feature for acetaminophen-induced ototoxicity.
Formaldehyde induces ferroptosis in hippocampal neuronal cells by upregulation of the Warburg effect.
Fucoxanthin extracted from Laminaria Japonica inhibits metastasis and enhances the sensitivity of lung cancer to Gefitinib.
A deafness-associated tRNA mutation caused pleiotropic effects on the m1G37 modification, processing, stability and aminoacylation of tRNAIle and mitochondrial translation.
Circ-NOLC1 promotes epithelial ovarian cancer tumorigenesis and progression by binding ESRP1 and modulating CDK1 and RhoA expression.
Cdk5-Mediated Phosphorylation of Sirt1 Contributes to Podocyte Mitochondrial Dysfunction in Diabetic Nephropathy.
A key role of gut microbiota-vagus nerve/spleen axis in sleep deprivation-mediated aggravation of systemic inflammation after LPS administration.
Let-7a regulates EV secretion and mitochondrial oxidative phosphorylation by targeting SNAP23 in colorectal cancer.
Bushen Huoxue recipe attenuates early pregnancy loss via activating endometrial COX2-PGE2 angiogenic signaling in mice.
CDCA4 suppresses epithelial-mesenchymal transtion (EMT) and metastasis in Non-small cell lung cancer through modulating autophagy.
L-type amino acid transporter 1 is associated with chemoresistance in breast cancer via the promotion of amino acid metabolism.
Changes in the prefrontal cortex after the hippocampus was injected with Aβ25-35 via the P35/P25-CDK5-Tau hyperphosphorylation signaling pathway.
Eradicating intracellular MRSA via targeted delivery of lysostaphin and vancomycin with mannose-modified exosomes.
Metformin alleviates high glucose-induced ER stress and inflammation by inhibiting the interaction between caveolin1 and AMPKα in rat astrocytes.
ActivinA activates Notch1-Shh signaling to regulate proliferation in C2C12 skeletal muscle cells.
Disrupted eNOS activity and expression account for vasodilator dysfunction in different stage of sepsis.
Anti-renal interstitial fibrosis effect of norcantharidin is exerted through inhibition of PP2Ac-mediated C-terminal phosphorylation of Smad3.
Syndecan 4 contributes to osteoclast differentiation induced by RANKL through enhancing autophagy.
Type 1 interferon aggravates lipopolysaccharide-induced sepsis through upregulating Caspase-11 and Gasdermin D.
Effect of claudin 1 on cell proliferation, migration and apoptosis in human cervical squamous cell carcinoma.
Sodium alginate/collagen hydrogel loaded with human umbilical cord mesenchymal stem cells promotes wound healing and skin remodeling.
Downregulating lncRNA PRNCR1 ameliorates LPS-induced pulmonary vascular endothelial cell injury by modulating miR-330-5p/TLR4 axis.
NPM1 mutant maintains ULK1 protein stability via TRAF6-dependent ubiquitination to promote autophagic cell survival in leukemia.
Cell membrane-encapsulated magnetic nanoparticles for enhancing natural killer cell-mediated cancer immunotherapy.
BML-111, the lipoxin A4 agonist, modulates VEGF or CoCl2-induced migration, angiogenesis and permeability in tumor-derived endothelial cells.
MicroRNA‑338‑3p regulates age‑associated osteoporosis via targeting PCSK5.
Luteolin attenuates angiotensin II‑induced renal damage in apolipoprotein E‑deficient mice.
Exercise reduces hyperlipidemia-induced kidney damage in apolipoprotein E-deficient mice.
F-Box protein 4 inhibits progression of papillary thyroid cancer.
Novel clerodane-type diterpenoid Cintelactone A suppresses lipopolysaccharide -induced inflammation by promoting ubiquitination, proteasomal degradation of TRAF6.
Osteogenic differentiation and calcification of human aortic smooth muscle cells is induced by the RCN2/STAT3/miR-155-5p feedback loop.
Study on the protective effect and mechanism of Dicliptera chinensis (L.) Juss (Acanthaceae) polysaccharide on immune liver injury induced by LPS.
Impact of knockdown LincRNA-Cox2 on apoptosis of macrophage infected with Bacillus Calmette-Guérin.
Bach2 overexpression represses Th9 cell differentiation by suppressing IRF4 expression in systemic lupus erythematosus.
Hypothermic oxygenated perfusion inhibits HECTD3-mediated TRAF3 polyubiquitination to alleviate DCD liver ischemia-reperfusion injury.
An ESCRT-dependent step in fatty acid transfer from lipid droplets to mitochondria through VPS13D-TSG101 interactions.
SEPHS1 promotes SMAD2/3/4 expression and hepatocellular carcinoma cells invasion.
Anti-NMDAR encephalitis induced in mice by active immunization with a peptide from the amino-terminal domain of the GluN1 subunit.
Macrophage migration inhibitory factor activates the inflammatory response in joint capsule fibroblasts following post-traumatic joint contracture.
Rational design and synthesis of 6-aryl-6H-benzo[c]chromenes as non-steroidal progesterone receptor antagonists for use against cancers.
A genome-wide CRISPR screen identifies host factors that regulate SARS-CoV-2 entry.
Stabilizing mast cells improves acute lung injury after orthotopic liver transplantation via promotion of apoptosis in polymorphonuclear neutrophils.
Prenylated xanthones from mangosteen (Garcinia mangostana) activate the AhR and Nrf2 pathways and protect intestinal barrier integrity in HT-29 cells.
ABIN-1 is a key regulator in RIPK1-dependent apoptosis (RDA) and necroptosis, and ABIN-1 deficiency potentiates necroptosis-based cancer therapy in colorectal cancer.
Ataxia-telangiectasia mutated interacts with Parkin and induces mitophagy independent of kinase activity. Evidence from mantle cell lymphoma.
Compound Kushen Injection intervenes metabolic reprogramming and epithelial-mesenchymal transition of HCC via regulating β-catenin/c-Myc signaling.
Dendrobium nobile Lindl alkaloid attenuates 6-OHDA-induced dopamine neurotoxicity.
Simiao Qingwen Baidu decoction inhibits Epstein-Barr virus-induced B lymphoproliferative disease and lytic viral replication.
Chrysanthemi Flos extract alleviated acetaminophen-induced rat liver injury via inhibiting oxidative stress and apoptosis based on network pharmacology analysis.
Bone marrow macrophage-derived exosomal miR-143-5p contributes to insulin resistance in hepatocytes by repressing MKP5.
Hsa_circ_0042823 accelerates cancer progression via miR-877-5p/FOXM1 axis in laryngeal squamous cell carcinoma.
Azathioprine pretreatment ameliorates myocardial ischaemia reperfusion injury in diabetic rats by reducing oxidative stress, apoptosis, and inflammation.
Triptolide regulates oxidative stress and inflammation leading to hepatotoxicity via inducing CYP2E1.
Non-canonical activation of the ER stress sensor ATF6 by Legionella pneumophila effectors.
Ramelteon Mitigates Free Fatty Acid (FFA)-Induced Attachment of Monocytes to Brain Vascular Endothelial Cells.
Acetabular development and fate of inverted limbus in rabbits: Experimental observation from an animal model.
Bergenin alleviates H2 O2 -induced oxidative stress and apoptosis in nucleus pulposus cells: Involvement of the PPAR-γ/NF-κB pathway.
ChREBP deficiency alleviates apoptosis by inhibiting TXNIP/oxidative stress in diabetic nephropathy.
Low EGR1 expression predicts poor prognosis in clear cell renal cell carcinoma.
TRIP4 transcriptionally activates DDIT4 and subsequent mTOR signaling to promote glioma progression.
Pretreatment of Indobufen and Aspirin and their Combinations with Clopidogrel or Ticagrelor Alleviates Inflammasome Mediated Pyroptosis Via Inhibiting NF-κB/NLRP3 Pathway in Ischemic Stroke.
Empagliflozin protects diabetic pancreatic tissue from damage by inhibiting the activation of the NLRP3/caspase-1/GSDMD pathway in pancreatic β cells: in vitro and in vivo studies.
The effects of Omarigliptin on promoting osteoblastic differentiation.
High expression of transmembrane P24 trafficking protein 9 predicts poor prognosis in breast carcinoma.
Silencing circular RNA circ_0054537 and upregulating microRNA-640 suppress malignant progression of renal cell carcinoma via regulating neuronal pentraxin-2 (NPTX2).
M2 Macrophage-derived exosomal miR-501 contributes to pubococcygeal muscle regeneration.
Biomimetic amphiphilic FAAP NPs nanoparticles: Synthesis, characterization and antivirus activity.
Fyn kinase regulates dopaminergic neuronal apoptosis in animal and cell models of high glucose (HG) treatment.
Long non-coding RNA CRNDE exacerbates NPC advancement mediated by the miR-545-5p/CCND2 axis.
Aureonitol Analogues and Orsellinic Acid Esters Isolated from Chaetomium elatum and Their Antineuroinflammatory Activity.
Calcium alleviates fluoride-induced kidney damage via FAS/FASL, TNFR/TNF, DR5/TRAIL pathways in rats.
Circular RNA circEsyt2 regulates vascular smooth muscle cell remodeling via splicing regulation.
Phosphatidylinositol 3,4,5-Trisphosphate-Dependent Rac Exchanger 2 Protein Facilitates Glioma Progression via Akt and Stat3 Signaling.
Guanosine and uridine alleviate airway inflammation via inhibition of the MAPK and NF-κB signals in OVA-induced asthmatic mice.
Diosgenin Protects Against Kidney Injury and Mitochondrial Apoptosis Induced by 3-MCPD Through the Regulation of ER Stress, Ca2+ Homeostasis, and Bcl2 Expression.
Dental pulp stem cell-derived exosomes alleviate cerebral ischaemia-reperfusion injury through suppressing inflammatory response.
Hippocampal CA1 theta burst-induced LTP from weaning to adulthood: Cellular and molecular mechanisms in young male rats revisited.
Glutaredoxin 1 protects neurons from oxygen-glucose deprivation/reoxygenation (OGD/R)-induced apoptosis and oxidative stress via the modulation of GSK-3β/Nrf2 signaling.
MicroRNA-122 contributes to lipopolysaccharide-induced acute kidney injury via down-regulating the vitamin D receptor in the kidney.
H2S Attenuates Sleep Deprivation-Induced Cognitive Impairment by Reducing Excessive Autophagy via Hippocampal Sirt-1 in WISTAR RATS.
CQMUH-011 Inhibits LPS-Induced Microglia Activation and Ameliorates Brain Ischemic Injury in Mice.
Quercetin hinders microglial activation to alleviate neurotoxicity via the interplay between NLRP3 inflammasome and mitophagy.
The p53/p21/p16 and PI3K/Akt signaling pathways are involved in the ameliorative effects of maltol on D-galactose-induced liver and kidney aging and injury.
LncRNA-AC006129.1 reactivates a SOCS3-mediated anti-inflammatory response through DNA methylation-mediated CIC downregulation in schizophrenia.
The molecular mechanism underlying mitophagy-mediated hippocampal neuron apoptosis in diabetes-related depression.
Resveratrol affects the expression of uric acid transporter by improving inflammation.
Aggravation of hepatic ischemia‑reperfusion injury with increased inflammatory cell infiltration is associated with the TGF‑β/Smad3 signaling pathway.
miR-320a in serum exosomes promotes myocardial fibroblast proliferation via regulating the PIK3CA/Akt/mTOR signaling pathway in HEH2 cells.
Augmenter of liver regeneration ameliorates ischemia-reperfusion injury in steatotic liver via inhibition of the TLR4/NF-κB pathway.
DNMT1-mediated PPARα methylation aggravates damage of retinal tissues in diabetic retinopathy mice.
Ginsenoside Rg5 Improves Insulin Resistance and Mitochondrial Biogenesis of Liver via Regulation of the Sirt1/PGC-1α Signaling Pathway in db/db Mice.
YWHAZ interacts with DAAM1 to promote cell migration in breast cancer.
Effects of RNA methylation N6-methyladenosine regulators on malignant progression and prognosis of melanoma.
The Performance of HepG2 and HepaRG Systems through the Glass of Acetaminophen-Induced Toxicity.
Reactive microglia enhance the transmission of exosomal α-synuclein via toll-like receptor 2.
Expression pattern and regulatory effect of lysine-specific demethylase 2A gene in clear cell renal cell carcinoma.
Serum exosomal pregnancy zone protein as a promising biomarker in inflammatory bowel disease.
CIHH protects the heart against left ventricular remodelling and myocardial fibrosis by balancing the renin-angiotensin system in SHR.
Virtual screening identified natural Keap1-Nrf2 PPI inhibitor alleviates inflammatory osteoporosis through Nrf2-mir214-Traf3 axis.
Contribution of the NLRP3/IL-1β axis to impaired vasodilation in sepsis through facilitation of eNOS proteolysis and the protective role of melatonin.
Autocrined leptin promotes proliferation of non-small cell lung cancer (NSCLC) via PI3K/AKT and p53 pathways.
Morusin inhibits the growth of human colorectal cancer HCT116‑derived sphere‑forming cells via the inactivation of Akt pathway.
MMP11 promotes the proliferation and progression of breast cancer through stabilizing Smad2 protein.
BOP1 Silencing Suppresses Gastric Cancer Proliferation through p53 Modulation.
Effect of luteinizing hormone concentration on transcriptome and subcellular organelle phenotype of ovarian granulosa cells.
CRSP8 promotes thyroid cancer progression by antagonizing IKKα-induced cell differentiation.
Enhanced response to PD-L1 silencing by modulation of TME via balancing glucose metabolism and robust co-delivery of siRNA/Resveratrol with dual-responsive polyplexes.
Zinc provides neuroprotection by regulating NLRP3 inflammasome through autophagy and ubiquitination in a spinal contusion injury model.
Honokiol induces paraptosis-like cell death of acute promyelocytic leukemia via mTOR & MAPK signaling pathways activation.
Oxymatrine reduces expression of programmed death-ligand 1 by promoting DNA demethylation in colorectal cancer cells.
Abnormal Glu/mGluR2/3/PI3K pathway in the hippocampal neurovascular unit leads to diabetes-related depression.
Involvement of NADPH oxidase in patulin-induced oxidative damage and cytotoxicity in HEK293 cells.
SPT6 recruits SND1 to co-activate human telomerase reverse transcriptase to promote colon cancer progression.
Change on apoptosis, autophagy and mitochondria of the Harderian gland in Cricetulus barabensis during age.
Downregulation of circular RNA circDOCK7 identified from diabetic rats after sleeve gastrectomy contributes to hepatocyte apoptosis through regulating miR-139-3p and MCM3.
Smooth muscle-specific HuR knockout induces defective autophagy and atherosclerosis.
GCG inhibits SARS-CoV-2 replication by disrupting the liquid phase condensation of its nucleocapsid protein.
KLF5-mediated Eppk1 expression promotes cell proliferation in cervical cancer via the p38 signaling pathway.
Xanthine oxidase inhibitory activity and antihyperuricemic effect of Moringa oleifera Lam. leaf hydrolysate rich in phenolics and peptides.
cAMP-PKA signaling is involved in regulation of spinal HCN channels function in diabetic neuropathic pain.
The SRSF1/circATP5B/miR-185-5p/HOXB5 feedback loop regulates the proliferation of glioma stem cells via the IL6-mediated JAK2/STAT3 signaling pathway.
Spleen Tyrosine Kinase Mediates Microglial Activation in Mice With Diabetic Retinopathy.
REG γ knockdown suppresses proliferation by inducing apoptosis and cell cycle arrest in osteosarcoma.
Glutamate-Cysteine Ligase Catalytic Subunit Attenuated Hepatitis C Virus-Related Liver Fibrosis and Suppressed Endoplasmic Reticulum Stress.
Promotion of cadmium uptake and cadmium-induced toxicity by the copper transporter CTR1 in HepG2 and ZFL cells.
The Novel Synthetic Triterpene Methyl 3β-O-[4-(2-Aminoethylamino)-4-oxo-butyryl]olean-12-ene-28-oate Inhibits Breast Tumor Cell Growth in Vitro and in Vivo.
Baicalin Inhibits Coxsackievirus B3 Replication by Reducing Cellular Lipid Synthesis.
Anti-inflammation and anti-apoptosis effects of growth arrest-specific protein 6 in acute liver injury induced by LPS/D-GalN in mice.
Systematic investigation of biomarker-like role of ARHGDIB in breast cancer.
Xiao-Qing-Long-Tang Maintains Cardiac Function during Heart Failure with Reduced Ejection Fraction in Salt-Sensitive Rats by Regulating the Imbalance of Cardiac Sympathetic Innervation.
Phloretin Modulates Human Th17/Treg Cell Differentiation In Vitro via AMPK Signaling.
Role of Nrf2 in Lipopolysaccharide-Induced Acute Kidney Injury: Protection by Human Umbilical Cord Blood Mononuclear Cells.
Heme Oxygenase-1 Suppresses Wnt Signaling Pathway in Nonalcoholic Steatohepatitis-Related Liver Fibrosis.
Thymoquinone Protects against Hyperlipidemia-Induced Cardiac Damage in Low-Density Lipoprotein Receptor-Deficient (LDL-R-/-) Mice via Its Anti-inflammatory and Antipyroptotic Effects.
Electroacupuncture Pretreatment Alleviates LPS-Induced Acute Respiratory Distress Syndrome via Regulating the PPAR Gamma/NF-Kappa B Signaling Pathway.
Silencing ARAF Suppresses the Malignant Phenotypes of Gallbladder Cancer Cells.
Ellagic Acid Protects Dopamine Neurons via Inhibition of NLRP3 Inflammasome Activation in Microglia.
miR-876 Inhibits EMT and Liver Fibrosis via POSTN to Suppress Metastasis in Hepatocellular Carcinoma.
Anti-Inflammatory and Antioxidant Effect of Eucommia ulmoides Polysaccharide in Hepatic Ischemia-Reperfusion Injury by Regulating ROS and the TLR-4-NF-κB Pathway.
Effects of Hydrogen-rich Water on the PI3K/AKT Signaling Pathway in Rats with Myocardial Ischemia-reperfusion Injury.
A glycolysis-based 4-mRNA signature correlates with the prognosis and cell cycle process in patients with bladder cancer.
Structure-based discovery of neoandrographolide as a novel inhibitor of Rab5 to suppress cancer growth.
Nicotinamide Riboside Enhances Mitochondrial Proteostasis and Adult Neurogenesis through Activation of Mitochondrial Unfolded Protein Response Signaling in the Brain of ALS SOD1G93A Mice.
Methylglyoxal and D-lactate in cisplatin-induced acute kidney injury: Investigation of the potential mechanism via fluorogenic derivatization liquid chromatography-tandem mass spectrometry (FD-LC-MS/MS) proteomic analysis.
Interferon regulatory factor 7 mediates obesity-associated MCP-1 transcription.
MicroRNA-9 mediated the protective effect of ferulic acid on hypoxic-ischemic brain damage in neonatal rats.
The effect of autophagy and mitochondrial fission on Harderian gland is greater than apoptosis in male hamsters during different photoperiods.
Utilizing methylglyoxal and D-lactate in urine to evaluate saikosaponin C treatment in mice with accelerated nephrotoxic serum nephritis.
Effect of prednisolone on glyoxalase 1 in an inbred mouse model of aristolochic acid nephropathy using a proteomics method with fluorogenic derivatization-liquid chromatography-tandem mass spectrometry.
Protective effects of essential oil from Fructus Alpiniae zerumbet on retinal Müller gliosis via the PPAR-γ-p-CREB signaling pathway.
MicroRNA 885-5p Inhibits Hepatocellular Carcinoma Metastasis by Repressing AEG1.
Bufalin Induces Glioma Cell Death by Apoptosis or Necroptosis.
The Acetone Indigo Red Dehydrating Agent IF203 Induces HepG2 Cell Death Through Cell Cycle Arrest, Autophagy and Apoptosis.
MicroRNA-375 Targets ATG14 to Inhibit Autophagy and Sensitize Hepatocellular Carcinoma Cells to Sorafenib.
Dihydroartemisinin Prevents Progression and Metastasis of Head and Neck Squamous Cell Carcinoma by Inhibiting Polarization of Macrophages in Tumor Microenvironment.
Proteomics Analysis of Brain Tissue in a Rat Model of Ischemic Stroke in the Acute Phase.
The Regulatory Mechanism and Biological Significance of Mitochondrial Calcium Uniporter in the Migration, Invasion, Angiogenesis and Growth of Gastric Cancer.
Melatonin ameliorates hyperglycaemia-induced renal inflammation by inhibiting the activation of TLR4 and TGF-β1/Smad3 signalling pathway.
Fenofibrate-induced mitochondrial dysfunction and metabolic reprogramming reversal: the anti-tumor effects in gastric carcinoma cells mediated by the PPAR pathway.
Selaginellin B induces apoptosis and autophagy in pancreatic cancer cells via the JAK2/STAT3 signaling pathway.
Identification of FADS1 Through Common Gene Expression Profiles for Predicting Survival in Patients with Bladder Cancer.
Blocking circ_0013912 Suppressed Cell Growth, Migration and Invasion of Pancreatic Ductal Adenocarcinoma Cells in vitro and in vivo Partially Through Sponging miR-7-5p.
The Clinical Relevance and Function of Krüppel-Like Factor 16 in Breast Cancer.
The LINC00365/SCGB2A1 (Mammaglobin B) Axis Down-Regulates NF-κB Signaling and Is Associated with the Progression of Gastric Cancer.
Inhibition of Skp2 Sensitizes Chronic Myeloid Leukemia Cells to Imatinib.
LINC00963 Promotes Ovarian Cancer Proliferation, Migration and EMT via the miR-378g /CHI3L1 Axis.
Dl-3-n-Butylphthalide Promotes Remyelination and Suppresses Inflammation by Regulating AMPK/SIRT1 and STAT3/NF-κB Signaling in Chronic Cerebral Hypoperfusion.
Hypoxia-induced MFAP5 Promotes Tumor Migration and Invasion via AKT Pathway in Head and Neck Squamous Cell Carcinoma.
Weighted gene co-expression network analysis identifies CCNA2 as a treatment target of prostate cancer through inhibiting cell cycle.
miRNA-182 regulated MTSS1 inhibits proliferation and invasion in Glioma Cells.
Isoquercitrin Ameliorates Cisplatin-Induced Nephrotoxicity Via the Inhibition of Apoptosis, Inflammation, and Oxidative Stress.
Hydrogen Sulfide Attenuates High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease by Inhibiting Apoptosis and Promoting Autophagy via Reactive Oxygen Species/Phosphatidylinositol 3-Kinase/AKT/Mammalian Target of Rapamycin Signaling Pathway.
Integrated Analysis of Key Genes and Pathways Involved in Fetal Growth Restriction and Their Associations With the Dysregulation of the Maternal Immune System.
Mitochondrial DNA Haplogroup M7 Confers Disability in a Chinese Aging Population.
The Human-Specific STING Agonist G10 Activates Type I Interferon and the NLRP3 Inflammasome in Porcine Cells.
Notoginsenoside R1 Protects Against the Acrylamide-Induced Neurotoxicity via Upregulating Trx-1-Mediated ITGAV Expression: Involvement of Autophagy.
Fisetin Alleviated Bleomycin-Induced Pulmonary Fibrosis Partly by Rescuing Alveolar Epithelial Cells From Senescence.
Progesterone Regulates Glucose Metabolism Through Glucose Transporter 1 to Promote Endometrial Receptivity.
Photoperiod Affects Harderian Gland Morphology and Secretion in Female Cricetulus barabensis: Autophagy, Apoptosis, and Mitochondria.
Characterization and Neuroprotection Potential of Seleno-Polymannuronate.
Identification of Immune-Related Genes Contributing to the Development of Glioblastoma Using Weighted Gene Co-expression Network Analysis.
Liraglutide Ameliorates Erectile Dysfunction via Regulating Oxidative Stress, the RhoA/ROCK Pathway and Autophagy in Diabetes Mellitus.
NNK-mediated upregulation of DEPDC1 stimulates the progression of oral squamous cell carcinoma by inhibiting CYP27B1 expression.
Novel ESCC-related gene ZNF750 as potential Prognostic biomarker and inhibits Epithelial-Mesenchymal Transition through directly depressing SNAI1 promoter in ESCC.
MicroRNA-590-3p inhibits invasion and metastasis in triple-negative breast cancer by targeting Slug.
An ultrasensitive hybridization chain reaction-amplified CRISPR-Cas12a aptasensor for extracellular vesicle surface protein quantification.
Hsp90 inhibitor HSP990 in very low dose upregulates EAAT2 and exerts potent antiepileptic activity.
LincRNA00494 Suppresses Non-small Cell Lung Cancer Cell Proliferation by Regulating SRCIN1 Expression as a ceRNA.
Critical roles of microRNA-141-3p and CHD8 in hypoxia/reoxygenation-induced cardiomyocyte apoptosis.
Inhibition of formyl peptide receptor 1 activity suppresses tumorigenicity in vivo and attenuates the invasion and migration of lung adenocarcinoma cells under hypoxic conditions in vitro.
Effects of the linoleic acid/docosahexaenoic acid ratio and concentration inducing autophagy in Raw264.7 cells against Staphylococcus aureus.
Hyperbaric oxygen treatment mitigates liver damage in mice with noise exposure.
RIP1 promotes proliferation through G2/M checkpoint progression and mediates cisplatin-induced apoptosis and necroptosis in human ovarian cancer cells.
Curcumin inhibits the growth of triple-negative breast cancer cells by silencing EZH2 and restoring DLC1 expression.
Cytisine attenuates bone loss of ovariectomy mouse by preventing RANKL-induced osteoclastogenesis.
Pretreatment with the ALDH2 activator Alda‑1 protects rat livers from ischemia/reperfusion injury by inducing autophagy.
Huoxuezhitong capsule ameliorates MIA-induced osteoarthritis of rats through suppressing PI3K/ Akt/ NF-κB pathway.
GALNT2 regulates ANGPTL3 cleavage in cells and in vivo of mice.
RNA N6-methyladenosine reader IGF2BP3 regulates cell cycle and angiogenesis in colon cancer.
Ability of Post-treatment Glycyrrhizic Acid to Mitigate Cerebral Ischemia/Reperfusion Injury in Diabetic Mice.
4-Acetylantroquinonol B Inhibits Osteoclastogenesis by Inhibiting the Autophagy Pathway in a Simulated Microgravity Model.
WITHDRAWN: Resveratrol partially prevents learning and memory deficits in rats exposed to gaseous formaldehyde.
Aberrant BMP2 Signaling in Patients Diagnosed with Osteoporosis.
MG53 Protects hUC-MSCs against Inflammatory Damage and Synergistically Enhances Their Efficacy in Neuroinflammation Injured Brain through Inhibiting NLRP3/Caspase-1/IL-1β Axis.
NGF receptors and PI3K/AKT pathway involved in glucose fluctuation-induced damage to neurons and α-lipoic acid treatment.
MicroRNA-128-1-5p attenuates myocardial ischemia/reperfusion injury by suppressing Gadd45g-mediated apoptotic signaling.
Amino Acids Regulate Cisplatin Insensitivity in Neuroblastoma.
Clusterin contributes to hepatitis C virus-related hepatocellular carcinoma by regulating autophagy.
Neuronostatin Promotion Soluble Aβ1-42 Oligomers: Induced Dysfunctional Brain Glucose Metabolism in Mice.
Inhibition of TBK1 by amlexanox attenuates paraquat-induced acute lung injury.
miR-21a in exosomes from Lewis lung carcinoma cells accelerates tumor growth through targeting PDCD4 to enhance expansion of myeloid-derived suppressor cells.
ROS-mediated PERK-eIF2α-ATF4 pathway plays an important role in arsenite-induced L-02 cells apoptosis via regulating CHOP-DR5 signaling.
Protective effects of isorhamnetin on pulmonary arterial hypertension: in vivo and in vitro studies.
Effect of autophagy on irradiation‑induced damage in osteoblast‑like MC3T3‑E1 cells.
STAT3-PTTG11 abrogation inhibits proliferation and induces apoptosis in malignant glioma cells.
SLC25A10 performs an oncogenic role in human osteosarcoma.
Involvement of p53 Acetylation in Growth Suppression of Cutaneous T-Cell Lymphomas Induced by HDAC Inhibition.
DUSP5 (dual-specificity protein phosphatase 5) suppresses BCG-induced autophagy via ERK 1/2 signaling pathway.
N-Ethyl-2-Pyrrolidinone-Substituted Flavan-3-Ols with Anti-inflammatory Activity in Lipopolysaccharide-Stimulated Macrophages Are Storage-Related Marker Compounds for Green Tea.
Regulatory coupling between long noncoding RNAs and senescence in irradiated microglia.
Novel mechanisms underlying anti-polycystic ovary like syndrome effects of electroacupuncture in rats: suppressing SREBP1 to mitigate insulin resistance, mitochondrial dysfunction and oxidative stress.
Impaired mitochondrial medium-chain fatty acid oxidation drives periportal macrovesicular steatosis in sirtuin-5 knockout mice.
HOTAIR maintains the stemness of ovarian cancer stem cells via the miR-206/TBX3 axis.
Hepatoprotective effects of Di Wu Yang Gan: A medicinal food against CCl4-induced hepatotoxicity in vivo and in vitro.
Nrf2 activation protects auditory hair cells from cisplatin-induced ototoxicity independent on mitochondrial ROS production.
Effect of Combined Sorafenib/Cisplatinum Treatment on the Autophagy and Proliferation of Hepatocellular Carcinoma hepG2 Cells in Vitro.
Treatment with 5-methoxytryptophan attenuates microglia-induced neuroinflammation in spinal cord trauma.
Echinacea polysaccharide alleviates LPS-induced lung injury via inhibiting inflammation, apoptosis and activation of the TLR4/NF-κB signal pathway.
Panax notoginseng saponin R1 modulates TNF-α/NF-κB signaling and attenuates allergic airway inflammation in asthma.
LMCD1 antisense RNA 1 (LMCD1-AS1) potentiates thyroid cancer cell growth and stemness via a positive feedback loop of LMCD1-AS1/miR-1287-5p/GLI2.
PKCβ/NF-κB pathway in diabetic atrial remodeling.
Induction of SPARC on Oxidative Stress, Inflammatory Phenotype Transformation, and Apoptosis of Human Brain Smooth Muscle Cells Via TGF-β1-NOX4 Pathway.
MicroRNA-145 suppresses osteogenic differentiation of human jaw bone marrow mesenchymal stem cells partially via targeting semaphorin 3A.
HIF-1α ameliorates tubular injury in diabetic nephropathy via HO-1-mediated control of mitochondrial dynamics.
miR-124-3p increases in high glucose induced osteocyte-derived exosomes and regulates galectin-3 expression: A possible mechanism in bone remodeling alteration in diabetic periodontitis.
Pharmacological Effects of Fasudil on Flap Survival in a Rodent Model.
Exosomes derived from smooth muscle cells ameliorate diabetes-induced erectile dysfunction by inhibiting fibrosis and modulating the NO/cGMP pathway.
Endoplasmic reticulum stress remodels alveolar bone formation after tooth extraction.
Downregulation of HDAC1 suppresses media degeneration by inhibiting the migration and phenotypic switch of aortic vascular smooth muscle cells in aortic dissection.
Insulin Promotes Corneal Nerve Repair and Wound Healing in Type 1 Diabetic Mice by Enhancing Wnt/β-Catenin Signaling.
Genkwadaphnin inhibits growth and invasion in hepatocellular carcinoma by blocking DHCR24-mediated cholesterol biosynthesis and lipid rafts formation.
Deficiency of pseudogene UPAT leads to hepatocellular carcinoma progression and forms a positive feedback loop with ZEB1.
miRNA-122-5p stimulates the proliferation and DNA synthesis and inhibits the early apoptosis of human spermatogonial stem cells by targeting CBL and competing with lncRNA CASC7.
Liver Expression of IGF2 and Related Proteins in ZBED6 Gene-Edited Pig by RNA-Seq.
miR-100-3p inhibits the adipogenic differentiation of hMSCs by targeting PIK3R1 via the PI3K/AKT signaling pathway.
HMGB1 mediates homocysteine-induced endothelial cells pyroptosis via cathepsin V-dependent pathway.
Polysaccharides from Armillariella tabescens mycelia ameliorate insulin resistance in type 2 diabetic mice.
Vernonia patula (Dryand.) Merr. and Leucas chinensis (Retz.) R. Brown exert anti-inflammatory activities and relieve oxidative stress via Nrf2 activation.
Lysine acetylation of F-actin decreases tropomyosin-based inhibition of actomyosin activity.
Oral recombinant methioninase increases TRAIL receptor-2 expression to regress pancreatic cancer in combination with agonist tigatuzumab in an orthotopic mouse model.
Artesunate induces autophagy dependent apoptosis through upregulating ROS and activating AMPK-mTOR-ULK1 axis in human bladder cancer cells.
Differential distribution and potential regulatory roles of estrogen receptor 2a and 2b in the pituitary of ricefield eel Monopterus albus.
Norcantharidin protects against renal interstitial fibrosis by suppressing TWEAK-mediated Smad3 phosphorylation.
The B7-H4 gene induces immune escape partly via upregulating the PD-1/Stat3 pathway in non-small cell lung cancer.
Protective effect of Berberine on reproductive function and spermatogenesis in diabetic rats via inhibition of ROS/JAK2/NFκB pathway.
Cannabinoid receptor 2 activation alleviates septic lung injury by promoting autophagy via inhibition of inflammatory mediator release.
miR-362 knock-down promotes proliferation and inhibits apoptosis in porcine immature Sertoli cells by targeting the RMI1 gene.
miR‑95 promotes osteosarcoma growth by targeting SCNN1A.
Establishment and characterization of an immortalized human chondrocyte cell line.
Characterization of a Novel Interleukin-1 Receptor Antagonist from Sheep (Ovis aries).
Relevance research between the expression of p16INK4a , Notch1, and hTERC genes: The development of HPV16-positive cervical cancer.
The role of PSMB5 in sodium arsenite-induced oxidative stress in L-02 cells.
MiR-145-5p alleviates hypoxia/reoxygenation- induced cardiac microvascular endothelial cell injury in coronary heart disease by inhibiting Smad4 expression.
AMPK-mTOR-ULK1 axis activation-dependent autophagy promotes hydroxycamptothecin-induced apoptosis in human bladder cancer cells.
Porcine parvovirus nonstructural protein NS1 activates NF-κB and it involves TLR2 signaling pathway.
Leptin mediates protection of hydrogen sulfide against 6-hydroxydopamine-induced Parkinson's disease: Involving enhancement in Warburg effect.
Expression and distribution of bone morphogenetic protein 4 and its antagonist Noggin in the skin of Kazakh sheep (Ovis aries) with a white and brown coat color.
ROS enhances the cytotoxicity of cisplatin by inducing apoptosis and autophagy in tongue squamous cell carcinoma cells.
Regulation of epidermal differentiation through KDF1-mediated deubiquitination of IKKα.
High glucose inhibits vascular endothelial Keap1/Nrf2/ARE signal pathway via downregulation of monomethyltransferase SET8 expression.
Effects of inhalation of sevoflurane at different concentrations on TRPV1 in airways of rats at different developmental stages.
Inhibition of the NLRP3-inflammasome prevents cognitive deficits in experimental autoimmune encephalomyelitis mice via the alteration of astrocyte phenotype.
LncRNA TROJAN promotes proliferation and resistance to CDK4/6 inhibitor via CDK2 transcriptional activation in ER+ breast cancer.
Overexpression of endogenous lipoic acid synthase attenuates pulmonary fibrosis induced by crystalline silica in mice.
Association analysis of DNA methyltransferases in IgA nephropathy.
Role of PEPT1in the transport of cinnabar in Caco-2 cells.
MTFP1 overexpression promotes the growth of oral squamous cell carcinoma by inducing ROS production.
Soluble Uric Acid Promotes Atherosclerosis via AMPK (AMP-Activated Protein Kinase)-Mediated Inflammation.
Sodium butyrate inhibits migration and induces AMPK-mTOR pathway-dependent autophagy and ROS-mediated apoptosis via the miR-139-5p/Bmi-1 axis in human bladder cancer cells.
Guizhi Decoction () Inhibits Cholinergic Transdifferentiation by Regulating Imbalance of NGF and LIF in Salt-Sensitive Hypertensive Heart Failure Rats.
Hyperthermic intraperitoneal chemotherapy with recombinant mutant human TNF-α and raltitrexed in mice with colorectal-peritoneal carcinomatosis.
Prenatal hypoxia inhibited propionate-evoked BK channels of mesenteric artery smooth muscle cells in offspring.
LncRNA MALAT1 knockdown inhibits cell migration and invasion by suppressing autophagy through miR-384/GOLM1 axis in glioma.
The Immunomodulatory Effects and Mechanisms of Tim-3 Action in the Early Stage of Mice with Severe Acute Pancreatitis.
Protein microarray analysis of cytokine expression changes in distal stumps after sciatic nerve transection.
CADM1 inhibits ovarian cancer cell proliferation and migration by potentially regulating the PI3K/Akt/mTOR pathway.
Metformin alleviates breast cancer through targeting high-mobility group AT-hook 2.
circFOXM1 promotes proliferation of non-small cell lung carcinoma cells by acting as a ceRNA to upregulate FAM83D.
Anti-neuroinflammatory effect of 3,4-dihydroxybenzaldehyde in ischemic stroke.
Role of autophagy and apoptosis in atrophic epithelium in oral submucous fibrosis.
The mechanism and role of intracellular α-ketoglutarate reduction in hepatic stellate cell activation.
Connective tissue growth factor as an unfavorable prognostic marker promotes the proliferation, migration, and invasion of gliomas.
The Late Domain of Prototype Foamy Virus Gag Facilitates Autophagic Clearance of Stress Granules by Promoting Amphisome Formation.
Critical role of toll-like receptor 4 (TLR4) in ricin toxin-induced inflammatory responses in macrophages.
Monocyte-derived extracellular vesicles upon treated by palmitate promote endothelial migration and monocytes attachment to endothelial cells.
Transgelin-2 contributes to proliferation and progression of hepatocellular carcinoma via regulating Annexin A2.
Effect of NF-κB signal pathway on mucus secretion induced by atmospheric PM2.5 in asthmatic rats.
Club cell 10-kDa protein (CC10) inhibits cPLA2/COX2 pathway to alleviate RSV-induced airway inflammation and AHR.
Microglia polarization of hippocampus is involved in the mechanism of Apelin-13 ameliorating chronic water immersion restraint stress-induced depression-like behavior in rats.
Dihydromethysticin, a natural molecule from Kava, suppresses the growth of colorectal cancer via the NLRC3/PI3K pathway.
Obesity induces preadipocyte CD36 expression promoting inflammation via the disruption of lysosomal calcium homeostasis and lysosome function.
Effects of cisplatin on the proliferation, invasion and apoptosis of breast cancer cells following β‑catenin silencing.
Compositional characterization of Pyrus ussuriensis Maxim and their antioxidant activities and induction of apoptosis in Bel-7402 cell.
Alda-1, an Aldehyde Dehydrogenase 2 Agonist, Improves Cutaneous Wound Healing by Activating Epidermal Keratinocytes via Akt/GSK-3β/β-Catenin Pathway.
Protein Phosphatase 2A Inhibiting β-Catenin Phosphorylation Contributes Critically to the Anti-renal Interstitial Fibrotic Effect of Norcantharidin.
Neuroprotective effects of notoginsenoside R1 by upregulating Trx-1 on acrylamide-induced neurotoxicity in PC12.
Hispidulin Inhibits Neuroinflammation in Lipopolysaccharide-Activated BV2 Microglia and Attenuates the Activation of Akt, NF-κB, and STAT3 Pathway.
CAFs-derived MFAP5 promotes bladder cancer malignant behavior through NOTCH2/HEY1 signaling.
Effect of STAT3 mediated epigenetic regulation in pre-eclampsia: an analysis of trial data.
Triiodothyronine potentiates angiogenesis-related factor expression through PI3K/AKT signaling pathway in human osteoarthritic osteoblasts.
Correction of Bcl-x splicing improves responses to imatinib in chronic myeloid leukaemia cells and mouse models.
Tubeimoside I improves survival of mice in sepsis by inhibiting inducible nitric oxide synthase expression.
CD4+ T cells and TGFβ1/MAPK signal pathway involved in the valvular hyperblastosis and fibrosis in patients with rheumatic heart disease.
Beneficial Effects of Theta-Burst Transcranial Magnetic Stimulation on Stroke Injury via Improving Neuronal Microenvironment and Mitochondrial Integrity.
Pseudolaric acid B induces mitotic arrest and apoptosis in both imatinib-sensitive and -resistant chronic myeloid leukaemia cells.
lncRNA MIRF Promotes Cardiac Apoptosis through the miR-26a-Bak1 Axis.
Paeoniflorin-6'-O-benzene sulfonate down-regulates CXCR4-Gβγ-PI3K/AKT mediated migration in fibroblast-like synoviocytes of rheumatoid arthritis by inhibiting GRK2 translocation.
Deletion of the Impg2 gene causes the degeneration of rod and cone cells in mice.
The RBP1-CKAP4 axis activates oncogenic autophagy and promotes cancer progression in oral squamous cell carcinoma.
A Gold(I) Complex Containing an Oleanolic Acid Derivative as a Potential Anti-Ovarian-Cancer Agent by Inhibiting TrxR and Activating ROS-Mediated ERS.
YBX1 mediates autophagy by targeting p110β and decreasing the sensitivity to cisplatin in NSCLC.
Role of mitochondrial acyl-CoA dehydrogenases in the metabolism of dicarboxylic fatty acids.
Drp1, a potential therapeutic target for Parkinson's disease, is involved in olfactory bulb pathological alteration in the Rotenone-induced rat model.
LncRNA-H19 induces hepatic stellate cell activation via upregulating alcohol dehydrogenase III-mediated retinoic acid signals.
Network Pharmacology and Bioactive Equivalence Assessment Integrated Strategy Driven Q-markers Discovery for Da-Cheng-Qi Decoction to Attenuate Intestinal Obstruction.
The up-regulation of NDRG1 by HIF counteracts the cancer-promoting effect of HIF in VHL-deficient clear cell renal cell carcinoma.
Pycnogenol achieves neuroprotective effects in rats with spinal cord injury by stabilizing the mitochondrial membrane potential.
Expression of lncRNA-HOTAIR in the serum of patients with lymph node metastasis of papillary thyroid carcinoma and its impact.
Leucine-rich α-2-glycoprotein-1 promotes diabetic corneal epithelial wound healing and nerve regeneration via regulation of matrix metalloproteinases.
Fingolimod (FTY720) improves postoperative cognitive dysfunction in mice subjected to D-galactose-induced aging.
Resveratrol slows the tumourigenesis of pancreatic cancer by inhibiting NFκB activation.
The Establishment and Application Studies on Precise Lysosome pH Indicator Based on Self-Decomposable Nanoparticles.
PD-L1 promotes tumor growth and progression by activating WIP and β-catenin signaling pathways and predicts poor prognosis in lung cancer.
Elevated expression of minichromosome maintenance 3 indicates poor outcomes and promotes G1/S cell cycle progression, proliferation, migration and invasion in colorectal cancer.
miR-5089-5p suppresses castration-resistant prostate cancer resistance to enzalutamide and metastasis via miR-5089-5p/SPINK1/ MAPK/MMP9 signaling.
Nintedanib Reduces Neutrophil Chemotaxis via Activating GRK2 in Bleomycin-Induced Pulmonary Fibrosis.
Myeloid cells protect intestinal epithelial barrier integrity through the angiogenin/plexin-B2 axis.
Euscaphic acid and Tormentic acid protect vascular endothelial cells against hypoxia-induced apoptosis via PI3K/AKT or ERK 1/2 signaling pathway.
Antitumor activity of celastrol by inhibition of proliferation, invasion, and migration in cholangiocarcinoma via PTEN/PI3K/Akt pathway.
PRRX1-induced epithelial-to-mesenchymal transition in salivary adenoid cystic carcinoma activates the metabolic reprogramming of free fatty acids to promote invasion and metastasis.
α-Ketoglutarate Modulates Macrophage Polarization Through Regulation of PPARγ Transcription and mTORC1/p70S6K Pathway to Ameliorate ALI/ARDS.
MiR-22 restrains proliferation of rheumatoid arthritis by targeting IL6R and may be concerned with the suppression of NF-κB pathway.
Scavenger receptor A impairs interferon response to HBV infection by limiting TRAF3 ubiquitination through recruiting OTUB1.
Fluoride induced mitochondrial impairment and PINK1-mediated mitophagy in Leydig cells of mice: In vivo and in vitro studies.
NRSN2 promotes breast cancer metastasis by activating PI3K/AKT/mTOR and NF-κB signaling pathways.
LINC00365-SCGB2A1 axis inhibits the viability of breast cancer through targeting NF-κB signaling.
MicroRNA-150 functions as a tumor suppressor and sensitizes osteosarcoma to doxorubicin-induced apoptosis by targeting RUNX2.
Matrine suppresses breast cancer metastasis by targeting ITGB1 and inhibiting epithelial-to-mesenchymal transition.
Effect of stromal cell-derived factor-1/CXCR4 axis in neural stem cell transplantation for Parkinson's disease.
Perilla oil regulates intestinal microbiota and alleviates insulin resistance through the PI3K/AKT signaling pathway in type-2 diabetic KKAy mice.
Involvement of proliferative and apoptotic factors in the development of hindgut in rat fetuses with ethylenethiourea-induced anorectal malformations.
Naturally-derived diterpenoid sphaeropsidin C as an activator of Nrf2/ARE pathway and its potential capability of relieving intracellular oxidative stress in human lung epithelial cells.
Human umbilical cord blood mononuclear cells protect against renal tubulointerstitial fibrosis in cisplatin-treated rats.
Deoxycholic Acid Upregulates the Reprogramming Factors KFL4 and OCT4 Through the IL-6/STAT3 Pathway in Esophageal Adenocarcinoma Cells.
Odor-mediated contextual learning induced memory consolidation and hippocampus development in neonate rat.
Aspirin enhances the sensitivity of colon cancer cells to cisplatin by abrogating the binding of NF-κB to the COX-2 promoter.
Protective effects of Salidroside on spermatogenesis in streptozotocin induced type-1 diabetic male mice by inhibiting oxidative stress mediated blood-testis barrier damage.
Suppression of Notch Signaling Stimulates Progesterone Synthesis by Enhancing the Expression of NR5A2 and NR2F2 in Porcine Granulosa Cells.
Romo1 is involved in the immune response of glioblastoma by regulating the function of macrophages.
The testis-specific gene 1700102P08Rik is essential for male fertility.
Asiaticoside nitric oxide gel accelerates diabetic cutaneous ulcers healing by activating Wnt/β-catenin signaling pathway.
FLI1 promotes protein translation via the transcriptional regulation of MKNK1 expression.
Screening for reproductive biomarkers in Bactrian camel via iTRAQ analysis of proteomes.
Resveratrol Downregulates STAT3 Expression and Astrocyte Activation in Primary Astrocyte Cultures of Rat.
Dendrobium Alkaloids Promote Neural Function After Cerebral Ischemia-Reperfusion Injury Through Inhibiting Pyroptosis Induced Neuronal Death in both In Vivo and In Vitro Models.
Study of the protective effect on damaged intestinal epithelial cells of rat multilineage-differentiating stress-enduring (Muse) cells.
Programmed cell death protein 1 promotes hepatitis B virus transmission through the regulation of ERK1/2-mediated trophoblasts differentiation.
Anti-insulin resistance effects of salidroside through mitochondrial quality control.
Inhibition of PFKFB3 suppresses osteoclastogenesis and prevents ovariectomy-induced bone loss.
Post-production modifications of murine mesenchymal stem cell (mMSC) derived extracellular vesicles (EVs) and impact on their cellular interaction.
CMIP promotes Herceptin resistance of HER2 positive gastric cancer cells.
Inhibition of calcineurin/NFATc4 signaling attenuates ventilator‑induced lung injury.
Effects of dexmedetomidine on oxidative stress and inflammatory response in lungs during mechanical ventilation in COPD rats.
Isorhamnetin attenuates Streptococcus suis virulence by inhibiting the inflammatory response.
Targeting the miR-122/PKM2 autophagy axis relieves arsenic stress.
A20 targets PFKL and glycolysis to inhibit the progression of hepatocellular carcinoma.
Colorectal cancer-derived exosomal miR-106b-3p promotes metastasis by down-regulating DLC-1 expression.
Minicircle DNA vector expressing interferon-lambda-3 inhibits hepatitis B virus replication and expression in hepatocyte-derived cell line.
A tropomyosin-like Meretrix meretrix Linnaeus polypeptide inhibits the proliferation and metastasis of glioma cells via microtubule polymerization and FAK/Akt/MMPs signaling.
Transactivation of miR-202-5p by Steroidogenic Factor 1 (SF1) Induces Apoptosis in Goat Granulosa Cells by Targeting TGFβR2.
GPAT3 deficiency alleviates insulin resistance and hepatic steatosis in a mouse model of severe congenital generalized lipodystrophy.
Protection of diabetes-induced kidney injury by phosphocreatine via the regulation of ERK/Nrf2/HO-1 signaling pathway.
Fine-tuning of the respiratory complexes stability and supercomplexes assembly in cells defective of complex III.
MicroRNA-217 ameliorates inflammatory damage of endothelial cells induced by oxidized LDL by targeting EGR1.
Alprostadil attenuates LPS-induced cardiomyocyte injury by inhibiting the Wnt5a/JNK/NF-κB pathway.
Exogenous CGRP Regulates Apoptosis and Autophagy to Alleviate Traumatic Brain Injury Through Akt/mTOR Signalling Pathway.
Acylglycerol kinase promotes the stemness of nasopharyngeal carcinoma cells by promoting β-catenin translocation to the nucleus through activating PI3K/Akt pathway.
Myeloid-derived suppressor cells promote epithelial ovarian cancer cell stemness by inducing the CSF2/p-STAT3 signalling pathway.
Co-delivery of paclitaxel and anti-VEGF siRNA by tripeptide lipid nanoparticle to enhance the anti-tumor activity for lung cancer therapy.
Poldip2 mediates blood-brain barrier disruption and cerebral edema by inducing AQP4 polarity loss in mouse bacterial meningitis model.
Inhibition of miRNA-29a regulates intestinal barrier function in diarrhea-predominant irritable bowel syndrome by upregulating ZO-1 and CLDN1.
Baicalin reversal of DNA hypermethylation-associated Klotho suppression ameliorates renal injury in type 1 diabetic mouse model.
Functional Food XingJiuTang Attenuates Alcohol-Induced Liver Injury by Regulating SIRT1/Nrf-2 Signaling Pathway.
TLR4 inhibition ameliorates mesencephalic substantia nigra injury in neonatal rats exposed to lipopolysaccharide via regulation of neuro-immunity.
Saikosaponin-d impedes hippocampal neurogenesis and causes cognitive deficits by inhibiting the survival of neural stem/progenitor cells via neurotrophin receptor signaling in mice.
Transforming growth factor beta type 1 (TGF-β) and hypoxia-inducible factor 1 (HIF-1) transcription complex as master regulators of the immunosuppressive protein galectin-9 expression in human cancer and embryonic cells.
MicroRNA-410-3p Binds to TLR2 and Alleviates Myocardial Mitochondrial Dysfunction and Chemokine Production in LPS-Induced Sepsis.
Curcumin protects rat hippocampal neurons against pseudorabies virus by regulating the BDNF/TrkB pathway.
Multi-walled carbon nanotubes decrease neuronal NO synthase in 3D brain organoids.
Decreased Expression of the Host Long-Noncoding RNA-GM Facilitates Viral Escape by Inhibiting the Kinase activity TBK1 via S-glutathionylation.
Initiation of PI3K/AKT pathway by IGF-1 decreases spinal cord injury-induced endothelial apoptosis and microvascular damage.
Discovery of potent small molecule PROTACs targeting mutant EGFR.
An autoregulatory feedback loop of miR-21/VMP1 is responsible for the abnormal expression of miR-21 in colorectal cancer cells.
Indoxyl sulfate promotes osteogenic differentiation of vascular smooth muscle cells by miR-155-5p-dependent downregulation of matrix Gla protein via ROS/NF-κB signaling.
Berberine alleviates cisplatin-induced acute kidney injury by regulating mitophagy via PINK 1/Parkin pathway.
Minocycline prevents the depressive-like behavior through inhibiting the release of HMGB1 from microglia and neurons.
Melatonin Ameliorates Renal Fibrosis Through the Inhibition of NF-κB and TGF-β1/Smad3 Pathways in db/db Diabetic Mice.
LncRNA XIST promotes chemoresistance of breast cancer cells to doxorubicin by sponging miR-200c-3p to upregulate ANLN.
Role of the Nucleotide-Binding Domain-Like Receptor Protein 3 Inflammasome in the Endothelial Dysfunction of Early Sepsis.
Integrin-α9 and Its Corresponding Ligands Play Regulatory Roles in Chronic Periodontitis.
The metabolic changes in the hippocampus of an atherosclerotic rat model and the regulation of aerobic training.
USP30 sets a trigger threshold for PINK1-PARKIN amplification of mitochondrial ubiquitylation.
PRDM16 orchestrates angiogenesis via neural differentiation in the developing brain.
MiR-34a affects G2 arrest in prostate cancer PC3 cells via Wnt pathway and inhibits cell growth and migration.
Vitamin D3 protects articular cartilage by inhibiting the Wnt/β-catenin signaling pathway.
Graphene oxide size-dependently altered lipid profiles in THP-1 macrophages.
Identification of EMT-related high-risk stage II colorectal cancer and characterisation of metastasis-related genes.
Activation of the Hedgehog Pathway Promotes Recovery of Neurological Function After Traumatic Brain Injury by Protecting the Neurovascular Unit.
A mutation found in esophageal cancer alters integrin β4 mRNA splicing.
BCCIPβ facilitates p53 ubiquitination via binding with E6 protein in high-risk HPV positive head and neck squamous cell carcinoma.
FB-15 inhibits MGC-803 cells growth by regulating energy metabolism.
BVES downregulation in non-syndromic tetralogy of fallot is associated with ventricular outflow tract stenosis.
ZEB1-Mediated Transcriptional Upregulation of circWWC3 Promotes Breast Cancer Progression through Activating Ras Signaling Pathway.
Computational repositioning of dimethyl fumarate for treating alcoholic liver disease.
Silychristin A activates Nrf2-HO-1/SOD2 pathway to reduce apoptosis and improve GLP-1 production through upregulation of estrogen receptor α in GLUTag cells.
Metformin ameliorates cardiac conduction delay by regulating microRNA-1 in mice.
Antagomirs targeting miR-142-5p attenuate pilocarpine-induced status epilepticus in mice.
Sulforaphane enhances the cisplatin sensitivity through regulating DNA repair and accumulation of intracellular cisplatin in ovarian cancer cells.
HIF-1α-upregulated lncRNA-H19 regulates lipid droplet metabolism through the AMPKα pathway in hepatic stellate cells.
Progesterone promotes endothelial nitric oxide synthase expression through enhancing nuclear progesterone receptor-SP-1 formation.
A multi-scale systems pharmacology approach uncovers the anti-cancer molecular mechanism of Ixabepilone.
Pyrazinamide alleviates rifampin-induced steatohepatitis in mice by regulating the activities of cholesterol-activated 7α-hydroxylase and lipoprotein lipase.
Exogenous hydrogen sulfide inhibits human melanoma cell development via suppression of the PI3K/AKT/ mTOR pathway.
Responses of intestinal morphology and function in offspring to heat stress in primiparous sows during late gestation.
Hydrogen sulfide inhibits cigarette smoke-induced inflammation and injury in alveolar epithelial cells by suppressing PHD2/HIF-1α/MAPK signaling pathway.
Lycopene attenuates body weight gain through induction of browning via regulation of peroxisome proliferator-activated receptor γ in high-fat diet-induced obese mice.
Identification of novel variants in the FZD4 gene associated with familial exudative vitreoretinopathy in Chinese families.
High- and low-virulent bovine Pasteurella multocida induced differential NLRP3 inflammasome activation and subsequent IL-1β secretion.
Stromal fibroblast-derived MFAP5 promotes the invasion and migration of breast cancer cells via Notch1/slug signaling.
Decreased basal and stimulated salivary parameters by histopathological lesions and secretory dysfunction of parotid and submandibular glands in rats with type 2 diabetes.
Novel nortriterpenoids with new skeletons and limonoids from the fruits of Evodia rutaecarpa and their bioactivities.
SMAD3/SP1 complex-mediated constitutive active loop between lncRNA PCAT7 and TGF-β signaling promotes prostate cancer bone metastasis.
Paradoxical Pro-inflammatory Responses by Human Macrophages to an Amoebae Host-Adapted Legionella Effector.
Calcium-sensing receptor promotes tumor proliferation and migration in human intrahepatic cholangiocarcinoma by targeting ERK signaling pathway.
Ablation of glutaredoxin 1 promotes pulmonary angiogenesis and alveolar formation in hyperoxia-injured lungs by modifying HIF-1α stability and inhibiting the NF-κB pathway.
An inducible intestinal epithelial cell-specific NHE3 knockout mouse model mimicking congenital sodium diarrhea.
RNA-seq analysis of potential lncRNAs for age-related hearing loss in a mouse model.
CACNA1H downregulation induces skeletal muscle atrophy involving endoplasmic reticulum stress activation and autophagy flux blockade.
MicroRNA-183 regulates lipopolysaccharide-induced oxidative stress of hippocampal neurons by targeting the fibronectin 1 gene.
Asperosaponin VI Injection Enhances Orthodontic Tooth Movement in Rats.
Posterior Neocortex-Specific Regulation of Neuronal Migration by CEP85L Identifies Maternal Centriole-Dependent Activation of CDK5.
Effect of KIF22 on promoting proliferation and migration of gastric cancer cells via MAPK-ERK pathways.
CCL5 derived from tumor-associated macrophages promotes prostate cancer stem cells and metastasis via activating β-catenin/STAT3 signaling.
Histone Deacetylation 10 Alleviates Inflammation After Intracerebral Hemorrhage via the PTPN22/NLRP3 Pathway in Rats.
All-trans-retinal induces autophagic cell death via oxidative stress and the endoplasmic reticulum stress pathway in human retinal pigment epithelial cells.
Targeting β2 subunit of Na+/K+-ATPase induces glioblastoma cell apoptosis through elevation of intracellular Ca2.
p66Shc Contributes to Liver Fibrosis through the Regulation of Mitochondrial Reactive Oxygen Species.
LncRNA-MTA2TR functions as a promoter in pancreatic cancer via driving deacetylation-dependent accumulation of HIF-1α.
STAT3 Contributes To Oncolytic Newcastle Disease Virus-Induced Immunogenic Cell Death in Melanoma Cells.
Antitumor Effects of Berberine on Gliomas via Inactivation of Caspase-1-Mediated IL-1β and IL-18 Release.
PNS-R1 inhibits Dex-induced bronchial epithelial cells apoptosis in asthma through mitochondrial apoptotic pathway.
MiR-24-3p Inhibits the Progression of Pancreatic Ductal Adenocarcinoma Through LAMB3 Downregulation.
The Binding of PD-L1 and Akt Facilitates Glioma Cell Invasion Upon Starvation via Akt/Autophagy/F-Actin Signaling.
Critical role of Tim-3 mediated autophagy in chronic stress induced immunosuppression.
MTHFD1L-Mediated Redox Homeostasis Promotes Tumor Progression in Tongue Squamous Cell Carcinoma.
Chrysanthemum extract attenuates hepatotoxicity via inhibiting oxidative stress in vivo and in vitro.
Mild hypothermia improves neurological outcome in mice after cardiopulmonary resuscitation through Silent Information Regulator 1-actviated autophagy.
Inhibition of Mitochondrial Complex I Aggravates Folic Acid-Induced Acute Kidney Injury.
SOCS3 control the activity of NF-κB induced by HSP70 via degradation of MyD88-adapter-like protein (Mal) in IPEC-J2 cells.
UHRF1 Promotes Proliferation of Human Adipose-Derived Stem Cells and Suppresses Adipogenesis via Inhibiting Peroxisome Proliferator-Activated Receptor γ.
Mechanisms of Aerobic Exercise Upregulating the Expression of Hippocampal Synaptic Plasticity-Associated Proteins in Diabetic Rats.
Spica Prunellae Extract Enhances Fluorouracil Sensitivity of 5-Fluorouracil-Resistant Human Colon Carcinoma HCT-8/5-FU Cells via TOP2α and miR-494.
Hepatitis B Virus X Protein-Induced RORγ Expression to Promote the Migration and Proliferation of Hepatocellular Carcinoma.
Primary Cilia Blockage Promotes the Malignant Behaviors of Hepatocellular Carcinoma via Induction of Autophagy.
Carnosine Protects Mouse Podocytes from High Glucose Induced Apoptosis through PI3K/AKT and Nrf2 Pathways.
Analysis of Toll-Like Receptors in Human Milk: Detection of Membrane-Bound and Soluble Forms.
Alleviation of Hepatic Ischemia Reperfusion Injury by Oleanolic Acid Pretreating via Reducing HMGB1 Release and Inhibiting Apoptosis and Autophagy.
Atorvastatin Inhibits Breast Cancer Cells by Downregulating PTEN/AKT Pathway via Promoting Ras Homolog Family Member B (RhoB).
Nrf2/Keap1/ARE Signaling Mediated an Antioxidative Protection of Human Placental Mesenchymal Stem Cells of Fetal Origin in Alveolar Epithelial Cells.
Jiawei Foshou San Induces Apoptosis in Ectopic Endometrium Based on Systems Pharmacology, Molecular Docking, and Experimental Evidence.
Jiedu Sangen Decoction Inhibits the Invasion and Metastasis of Colorectal Cancer Cells by Regulating EMT through the Hippo Signaling Pathway.
RAD51 is a potential marker for prognosis and regulates cell proliferation in pancreatic cancer.
Casticin inhibits nasopharyngeal carcinoma growth by targeting phosphoinositide 3-kinase.
SIRT6/HIF-1α axis promotes papillary thyroid cancer progression by inducing epithelial-mesenchymal transition.
TGF-β1 Induces Epithelial-Mesenchymal Transition of Chronic Sinusitis with Nasal Polyps through MicroRNA-21.
Anti-apoptotic effect of the Shh signaling pathway in cigarette smoke extract induced MLE 12 apoptosis.
P11 Loss-of-Function is Associated with Decreased Cell Proliferation and Neurobehavioral Disorders in Mice.
Glycolytic Enzyme PKM2 Mediates Autophagic Activation to Promote Cell Survival in NPM1-Mutated Leukemia.
LncRNA SLCO4A1-AS1 predicts poor prognosis and promotes proliferation and metastasis via the EGFR/MAPK pathway in colorectal cancer.
LncRNA expression profile during autophagy and Malat1 function in macrophages.
NAMPT overexpression alleviates alcohol-induced hepatic steatosis in mice.
Porous Se@SiO2 nanocomposite promotes migration and osteogenic differentiation of rat bone marrow mesenchymal stem cell to accelerate bone fracture healing in a rat model.
Inhibition of COX2/PGD2-Related Autophagy Is Involved in the Mechanism of Brain Injury in T2DM Rat.
Bone Mesenchymal Stem Cell-Derived Extracellular Vesicles Promote Recovery Following Spinal Cord Injury via Improvement of the Integrity of the Blood-Spinal Cord Barrier.
CITED1 contributes to the progression of papillary thyroid carcinoma via the Wnt/β-catenin signaling pathway.
GPX2 suppression of H2O2 stress regulates cervical cancer metastasis and apoptosis via activation of the β-catenin-WNT pathway.
SIRT6 promotes the Warburg effect of papillary thyroid cancer cell BCPAP through reactive oxygen species.
Prognostic implications and oncogenic roles of MYBL2 protein expression in esophageal squamous-cell carcinoma.
DHT deteriorates the progression of monocrotaline-induced pulmonary arterial hypertension: effects of endogenous and exogenous androgen.
miR-23a-5p inhibits cell proliferation and invasion in pancreatic ductal adenocarcinoma by suppressing ECM1 expression.
The IRE1α-XBP1 pathway function in hypoxia-induced pulmonary vascular remodeling, is upregulated by quercetin, inhibits apoptosis and partially reverses the effect of quercetin in PASMCs.
Rutin suppresses FNDC1 expression in bone marrow mesenchymal stem cells to inhibit postmenopausal osteoporosis.
The lncRNA HOXA11-AS regulates Rab3D expression by sponging miR-125a-5p promoting metastasis of osteosarcoma.
High expression of SMARCE1 predicts poor prognosis and promotes cell growth and metastasis in gastric cancer.
Catalpol Exerts a Neuroprotective Effect in the MPTP Mouse Model of Parkinson's Disease.
MARCH5 overexpression contributes to tumor growth and metastasis and associates with poor survival in breast cancer.
AAV-Mig-6 Increase the Efficacy of TAE in VX2 Rabbit Model, Is Associated With JNK Mediated Autophagy.
Up-regulation of EMT-related gene VCAN by NPM1 mutant-driven TGF-β/cPML signalling promotes leukemia cell invasion.
SIRT5 Promotes Hepatocellular Carcinoma Progression by Regulating Mitochondrial Apoptosis.
Involvement of Actin-Regulating Factor Cofilin in the Inclusion Body Formation and RNA Synthesis of Human Parainfluenza Virus Type 3 via Interaction With the Nucleoprotein.
Naringenin Produces Neuroprotection Against LPS-Induced Dopamine Neurotoxicity via the Inhibition of Microglial NLRP3 Inflammasome Activation.
miR-181b-5p May Regulate Muscle Growth in Tilapia by Targeting Myostatin b.
TLR4/NF-κB Signaling Induces GSDMD-Related Pyroptosis in Tubular Cells in Diabetic Kidney Disease.
The Wnt/β-Catenin/LEF1 Pathway Promotes Cell Proliferation at Least in Part Through Direct Upregulation of miR-17-92 Cluster.
Combined melatonin and poricoic acid A inhibits renal fibrosis through modulating the interaction of Smad3 and β-catenin pathway in AKI-to-CKD continuum.
Protective Effects of 18β-Glycyrrhetinic Acid on Monocrotaline-Induced Pulmonary Arterial Hypertension in Rats.
Downregulation of Wnt3 Suppresses Colorectal Cancer Development Through Inhibiting Cell Proliferation and Migration.
The Therapeutic Effects of Treadmill Exercise on Osteoarthritis in Rats by Inhibiting the HDAC3/NF-KappaB Pathway in vivo and in vitro.
Protective mechanism of Taxifolin for chlorpyrifos neurotoxicity in BV2 cells.
Time-dependent C5a and C5aR expression in dental pulp cells following stimulation with LTA and LPS.
Fluorene-9-bisphenol inhibits epithelial-mesenchymal transition of human endometrial cancer Ishikawa cells by repressing TGF-β signaling pathway.
Hydrogen inhalation protects hypoxic-ischemic brain damage by attenuating inflammation and apoptosis in neonatal rats.
Resveratrol inhibits the invasion and metastasis of colon cancer through reversal of epithelial‑ mesenchymal transition via the AKT/GSK‑3β/Snail signaling pathway.
TAK242 suppresses the TLR4 signaling pathway and ameliorates DCD liver IRI in rats.
Mechanism Underlying the Protective Effect of Selenium on NO-Induced Oxidative Damage in Bovine Mammary Epithelial Cells.
Association between CIRP expression and hypoxic-ischemic brain injury in neonatal rats.
REG4 is an indicator for KRAS mutant lung adenocarcinoma with TTF-1 low expression.
Novel diterpenoid-type activators of the Keap1/Nrf2/ARE signaling pathway and their regulation of redox homeostasis.
Multi-walled carbon nanotubes (MWCNTs) promoted lipid accumulation in THP-1 macrophages through modulation of endoplasmic reticulum (ER) stress.
Targeting Exosomal EBV-LMP1 Transfer and miR-203 Expression via the NF-κB Pathway: The Therapeutic Role of Aspirin in NPC.
Enhancing the retrograde axonal transport by curcumin promotes autophagic flux in N2a/APP695swe cells.
ROS/KRAS/AMPK Signaling Contributes to Gemcitabine-Induced Stem-like Cell Properties in Pancreatic Cancer.
Establishment of an Experimental Intracerebral Haemorrhage Model for Mass Effect Research using a Thermo-sensitive Hydrogel.
Protective effects of 18β-glycyrrhetinic acid on pulmonary arterial hypertension via regulation of Rho A/Rho kinsase pathway.
OPA1 overexpression ameliorates mitochondrial cristae remodeling, mitochondrial dysfunction, and neuronal apoptosis in prion diseases.
Structural Characterization and Antioxidant Activity of Polysaccharides from Athyrium multidentatum (Doll.) Ching in d-Galactose-Induced Aging Mice via PI3K/AKT Pathway.
Long Noncoding RNA FAM225A Promotes Nasopharyngeal Carcinoma Tumorigenesis and Metastasis by Acting as ceRNA to Sponge miR-590-3p/miR-1275 and Upregulate ITGB3.
Age-Associated Dopaminergic Neuron Loss and Midbrain Glia Cell Phenotypic Polarization.
Antinociceptive effect of isoorientin against neuropathic pain induced by the chronic constriction injury of the sciatic nerve in mice.
Macrophage migration inhibitory factor promotes the invasion and metastasis of oral squamous cell carcinoma through matrix metalloprotein-2/9.
Bromodomain inhibitor jq1 induces cell cycle arrest and apoptosis of glioma stem cells through the VEGF/PI3K/AKT signaling pathway.
Paip1 Indicated Poor Prognosis in Cervical Cancer and Promoted Cervical Carcinogenesis.
Babao Dan induces gastric cancer cell apoptosis via regulating MAPK and NF-κB signaling pathways.
Downregulation of nicotinamide N-methyltransferase inhibits migration and epithelial-mesenchymal transition of esophageal squamous cell carcinoma via Wnt/β-catenin pathway.
Apatinib inhibits glycolysis by suppressing the VEGFR2/AKT1/SOX5/GLUT4 signaling pathway in ovarian cancer cells.
Propofol attenuates TNF-α-induced MMP-9 expression in human cerebral microvascular endothelial cells by inhibiting Ca2+/CAMK II/ERK/NF-κB signaling pathway.
A novel long noncoding RNA PGC1β-OT1 regulates adipocyte and osteoblast differentiation through antagonizing miR-148a-3p.
Whole-Exome Sequencing Analysis Identified Novel Mutations in the TSPAN12 Gene in Chinese Families with Familial Exudative Vitreoretinopathy.
Turnover of bile acids in liver, serum and caecal content by high-fat diet feeding affects hepatic steatosis in rats.
CX-F9, a novel RSK2 inhibitor, suppresses cutaneous melanoma cells proliferation and metastasis through regulating autophagy.
Novel ADAM-17 inhibitor ZLDI-8 inhibits the proliferation and metastasis of chemo-resistant non-small-cell lung cancer by reversing Notch and epithelial mesenchymal transition in vitro and in vivo.
RNA-Seq analysis of potential lncRNAs and genes for the anti-renal fibrotic effect of norcantharidin.
Neuroprotective effect of Vanillin on hypoxic-ischemic brain damage in neonatal rats.
Dehydroepiandrosterone alleviates E. Coli O157:H7-induced inflammation by preventing the activation of p38 MAPK and NF-κB pathways in mice peritoneal macrophages.
Oncogenic ADAM28 induces gemcitabine resistance and predicts a poor prognosis in pancreatic cancer.
Adipose tissue-derived omentin-1 attenuates arterial calcification via AMPK/Akt signaling pathway.
ROS-mediated inactivation of the PI3K/AKT pathway is involved in the antigastric cancer effects of thioredoxin reductase-1 inhibitor chaetocin.
Fractionated irradiation of right thorax induces abscopal damage on testes leading to decline in fertility.
HIF-1α contributes to Ang II-induced inflammatory cytokine production in podocytes.
The interference of DEHP in precocious puberty of females mediated by the hypothalamic IGF-1/PI3K/Akt/mTOR signaling pathway.
Young Blood Rescues the Cognition of Alzheimer's Model Mice by Restoring the Hippocampal Cholinergic Circuit.
PPAR-δ of orange-spotted grouper exerts antiviral activity against fish virus and regulates interferon signaling and inflammatory factors.
Piperine as a neuroprotective functional component in rats with cerebral ischemic injury.
Niban protein regulates apoptosis in HK-2 cells via caspase-dependent pathway.
Cadmium regulates von Willebrand factor and occludin expression in glomerular endothelial cells of mice in a TNF-α-dependent manner.
Wnt1 silencing enhances neurotoxicity induced by paraquat and maneb in SH-SY5Y cells.
Propionate relieves pentylenetetrazol-induced seizures, consequent mitochondrial disruption, neuron necrosis and neurological deficits in mice.
Iron dysregulation in vascular dementia: Focused on the AMPK/autophagy pathway.
Identification of predictors of drug sensitivity using patient-derived models of esophageal squamous cell carcinoma.
Hypertension-associated mitochondrial DNA 4401A>G mutation caused the aberrant processing of tRNAMet, all 8 tRNAs and ND6 mRNA in the light-strand transcript.
Dexmedetomidine inhibits neuronal apoptosis by inducing Sigma-1 receptor signaling in cerebral ischemia-reperfusion injury.
Oroxin B Induces Apoptosis by Down-Regulating MicroRNA-221 Resulting in the Inactivation of the PTEN/PI3K/AKT Pathway in Liver Cancer.
PP2Ac Modulates AMPK-Mediated Induction of Autophagy in Mycobacterium bovis-Infected Macrophages.
Protrudin modulates seizure activity through GABAA receptor regulation.
Folic acid delays age-related cognitive decline in senescence-accelerated mouse prone 8: alleviating telomere attrition as a potential mechanism.
Inhibition of Bcl-2 Synergistically Enhances the Antileukemic Activity of Midostaurin and Gilteritinib in Preclinical Models of FLT3-Mutated Acute Myeloid Leukemia.
Chitosan Ameliorates DSS-Induced Ulcerative Colitis Mice by Enhancing Intestinal Barrier Function and Improving Microflora.
Circ-ASH2L promotes tumor progression by sponging miR-34a to regulate Notch1 in pancreatic ductal adenocarcinoma.
Protective effects of Clec11a in islets against lipotoxicity via modulation of proliferation and lipid metabolism in mice.
Elevated Levels of Arachidonic Acid Metabolites in Follicular Fluid of PCOS Patients.
Melatonin protects against COPD by attenuating apoptosis and endoplasmic reticulum stress via upregulating SIRT1 expression in rats.
Functional analysis of the CXCR1a gene response to SGIV viral infection in grouper.
A novel tumor suppressor SPINK5 targets Wnt/β-catenin signaling pathway in esophageal cancer.
Microglial LOX-1/MAPKs/NF-κB positive loop promotes the vicious cycle of neuroinflammation and neural injury.
Activation of Nrf2 signaling by Icariin protects against 6-OHDA-induced neurotoxicity.
Circular RNA cMras inhibits lung adenocarcinoma progression via modulating miR-567/PTPRG regulatory pathway.
Eutopic endometrium from patients with endometriosis modulates the expression of CD36 and SIRP-α in peritoneal macrophages.
Induced Pluripotent Stem Cells Regulate Triggering Receptor Expressed on Myeloid Cell-1 Expression and the p38 Mitogen-Activated Protein Kinase Pathway in Endotoxin-Induced Acute Lung Injury.
HepaCAM Regulates Warburg Effect of Renal Cell Carcinoma via HIF-1α/NF-κB Signaling Pathway.
Kallikrein 12 Regulates Innate Resistance of Murine Macrophages against Mycobacterium bovis Infection by Modulating Autophagy and Apoptosis.
Predictable chronic mild stress promotes recovery from LPS-induced depression.
HMGB1 contributes to SASH1 methylation to attenuate astrocyte adhesion.
Nilotinib: A Tyrosine Kinase Inhibitor Mediates Resistance to Intracellular Mycobacterium Via Regulating Autophagy.
Glucose metabolic alterations in hippocampus of diabetes mellitus rats and the regulation of aerobic exercise.
Efficient Production of Human Norovirus-Specific IgY in Egg Yolks by Vaccination of Hens with a Recombinant Vesicular Stomatitis Virus Expressing VP1 Protein.
Neuroprotective Effect of Swertiamain on Cerebral Ischemia/Reperfusion Injury by Inducing the Nrf2 Protective Pathway.
Role of OXCT1 in ovine adipose and preadipocyte differentiation.
Quantitative proteomic profiling of tumor-associated vascular endothelial cells in colorectal cancer.
Repurposing of omeprazole for oligodendrocyte differentiation and remyelination.
Hepatoprotective effects and structure-activity relationship of five flavonoids against lipopolysaccharide/d-galactosamine induced acute liver failure in mice.
NS38 is required for aquareovirus replication via interaction with viral core proteins and host eIF3A.
CSE1L participates in regulating cell mitosis in human seminoma.
The endogenous retrovirus-derived long noncoding RNA TROJAN promotes triple-negative breast cancer progression via ZMYND8 degradation.
Regulation of Neurotransmitter Release by Amyloid Precursor Protein Through Synapsin Phosphorylation.
LncRNA EPB41L4A-AS1 regulates glycolysis and glutaminolysis by mediating nucleolar translocation of HDAC2.
The selective HDAC6 inhibitor Nexturastat A induces apoptosis, overcomes drug resistance and inhibits tumor growth in multiple myeloma.
iTRAQ-based quantitative proteomics reveals the neuroprotection of rhubarb in experimental intracerebral hemorrhage.
MicroRNA-596 acts as a tumor suppressor in gastric cancer and is upregulated by promotor demethylation.
Hypoxic BMSC-derived exosomal miRNAs promote metastasis of lung cancer cells via STAT3-induced EMT.
The methionine salvage pathway-involving ADI1 inhibits hepatoma growth by epigenetically altering genes expression via elevating S-adenosylmethionine.
S-1-Propenylcysteine augments BACH1 degradation and heme oxygenase 1 expression in a nitric oxide-dependent manner in endothelial cells.
The role of autophagy in the overexpression of MUC5AC in patients with chronic rhinosinusitis.
Clock mutant promotes osteoarthritis by inhibiting the acetylation of NFκB.
Cell survival controlled by lens-derived Sema3A-Nrp1 is vital on caffeine-suppressed corneal innervation during chick organogenesis.
Ghrelin regulates sepsis‑induced rat acute gastric injury.
Bronchial epithelial cell extracellular vesicles ameliorate epithelial-mesenchymal transition in COPD pathogenesis by alleviating M2 macrophage polarization.
YWHA/14-3-3 proteins recognize phosphorylated TFEB by a noncanonical mode for controlling TFEB cytoplasmic localization.
GDF-15 promotes mitochondrial function and proliferation in neuronal HT22 cells.
circ-CSPP1 promotes proliferation, invasion and migration of ovarian cancer cells by acting as a miR-1236-3p sponge.
Site-Specific Immobilization of β2-AR Using O6-Benzylguanine Derivative-Functionalized Supporter for High-Throughput Receptor-Targeting Lead Discovery.
Pseudogene RACGAP1P activates RACGAP1/Rho/ERK signalling axis as a competing endogenous RNA to promote hepatocellular carcinoma early recurrence.
iTRAQ-based proteomics analysis reveals the deregulated proteins related to liver toxicity induced by melamine with or without cyanuric acid in mice.
Transection of the cervical sympathetic trunk inhibits the progression of pulmonary arterial hypertension via ERK-1/2 Signalling.
The long non-coding RNA H19 induces hypoxia/reoxygenation injury by up-regulating autophagy in the hepatoma carcinoma cells.
Role of PM2.5 in the development and progression of COPD and its mechanisms.
Epidural adipose tissue-derived mesenchymal stem cell activation induced by lung cancer cells promotes malignancy and EMT of lung cancer.
The up-regulation of two identified wound healing specific proteins-HSP70 and lysozyme in regenerated Eisenia fetida through transcriptome analysis.
Reduction of SIRT1 blunts the protective effects of ischemic post-conditioning in diabetic mice by impairing the Akt signaling pathway.
MiR-664-2 impacts pubertal development in a precocious-puberty rat model through targeting the NMDA receptor-1†.
Protective effects of pyrroloquinoline quinine against oxidative stress-induced cellular senescence and inflammation in human renal tubular epithelial cells via Keap1/Nrf2 signaling pathway.
Exogenous hydrogen sulfide mitigates LPS + ATP-induced inflammation by inhibiting NLRP3 inflammasome activation and promoting autophagy in L02 cells.
Echinacoside Alleviates Hypoxic-Ischemic Brain Injury in Neonatal Rat by Enhancing Antioxidant Capacity and Inhibiting Apoptosis.
Normoxia is not favorable for maintaining stemness of human endothelial progenitor cells.
GSTO1 acts as a mediator in sodium fluoride-induced alterations of learning and memory related factors expressions in the hippocampus cell line.
c‑Jun N‑terminal kinase/transforming growth factor‑β/Smad3 pathway: Is it associated with endoplasmic reticulum stress‑mediated renal interstitial fibrosis?
Toxicity mechanism of sevoflurane in neural stem cells of rats through DNA methylation.
Aloperine suppresses human pulmonary vascular smooth muscle cell proliferation via inhibiting inflammatory response.
Deciphering novel biomarkers of lymph node metastasis of thyroid papillary microcarcinoma using proteomic analysis of ultrasound-guided fine-needle aspiration biopsy samples.
Precise and systematic survey of the efficacy of multicomponent drugs against functional dyspepsia.
Insulin secretion impairment induced by rosuvastatin partly though autophagy in INS-1E cells.
Nek2 augments sorafenib resistance by regulating the ubiquitination and localization of β-catenin in hepatocellular carcinoma.
miR-629-5p promotes growth and metastasis of hepatocellular carcinoma by activating β-catenin.
Mitophagy is a protective response against oxidative damage in bone marrow mesenchymal stem cells.
Multi-walled carbon nanotubes promoted lipid accumulation in human aortic smooth muscle cells.
Hypericum perforatum L. supplementation protects sciatic nerve injury-induced apoptotic, inflammatory and oxidative damage to muscle, blood and brain in rats.
S1P promotes inflammation-induced tube formation by HLECs via the S1PR1/NF-κB pathway.
Overexpression of CDCA8 promotes the malignant progression of cutaneous melanoma and leads to poor prognosis.
Regulation of host cell pyroptosis and cytokines production by Mycobacterium tuberculosis effector PPE60 requires LUBAC mediated NF-κB signaling.
Induction of Endoplasmic Reticulum Stress by Cadmium and Its Regulation on Nrf2 Signaling Pathway in Kidneys of Rats.
Radioprotective effects of roxadustat (FG-4592) in haematopoietic system.
BPTF promotes hepatocellular carcinoma growth by modulating hTERT signaling and cancer stem cell traits.
PARP inhibitor re‑sensitizes Adriamycin resistant leukemia cells through DNA damage and apoptosis.
Constitutive androstane receptor weakens the induction of panaxytriol on CYP3A4 by repressing the activation of pregnane X receptor.
DEP domain containing 1 predicts prognosis of hepatocellular carcinoma patients and regulates tumor proliferation and metastasis.
Zerumbone inhibits migration in ESCC via promoting Rac1 ubiquitination.
FS-7 inhibits MGC-803 cells growth in vitro and in vivo via down-regulating glycolysis.
Nerve injury elevates functional Cav3.2 channels in superficial spinal dorsal horn.
Dexamethasone interferes with osteoblasts formation during osteogenesis through altering IGF-1-mediated angiogenesis.
Differential response to lead toxicity in rat primary microglia and astrocytes.
Melatonin protects against sepsis-induced cardiac dysfunction by regulating apoptosis and autophagy via activation of SIRT1 in mice.
miR-429 and miR-424-5p inhibit cell proliferation and Ca2+ influx by downregulating CaSR in pulmonary artery smooth muscle cells.
Sulforaphane Improves Lipid Metabolism by Enhancing Mitochondrial Function and Biogenesis In Vivo and In Vitro.
Citrate reduced oxidative damage in stem cells by regulating cellular redox signaling pathways and represent a potential treatment for oxidative stress-induced diseases.
Strand break-induced replication fork collapse leads to C-circles, C-overhangs and telomeric recombination.
Exogenous Tetranectin Protects Against 1-Methyl-4-Phenylpyridine-Induced Neurotoxicity by Inhibiting Apoptosis and Autophagy Through Ribosomal Protein S6 Kinase Beta-1.
Interferon-alpha promotes immunosuppression through IFNAR1/STAT1 signalling in head and neck squamous cell carcinoma.
A coronary artery disease-associated tRNAThr mutation altered mitochondrial function, apoptosis and angiogenesis.
Protective effect of oxytocin on LPS-induced acute lung injury in mice.
Long noncoding RNA HOTAIR regulates autophagy via the miR-20b-5p/ATG7 axis in hepatic ischemia/reperfusion injury.
Carnosol as a Nrf2 Activator Improves Endothelial Barrier Function Through Antioxidative Mechanisms.
MiR-223-3p functions as a tumor suppressor in lung squamous cell carcinoma by miR-223-3p-mutant p53 regulatory feedback loop.
Autophagy inhibition potentiates the anti-angiogenic property of multikinase inhibitor anlotinib through JAK2/STAT3/VEGFA signaling in non-small cell lung cancer cells.
Protective Effect of Koumine, an Alkaloid from Gelsemium Sempervirens, on Injury Induced by H₂O₂ in IPEC-J2 Cells.
Blockade of glycolysis-dependent contraction by oroxylin a via inhibition of lactate dehydrogenase-a in hepatic stellate cells.
Identification of diterpenoid compounds that interfere with Fli-1 DNA binding to suppress leukemogenesis.
Nano-Gold Loaded with Resveratrol Enhance the Anti-Hepatoma Effect of Resveratrol In Vitro and In Vivo.
Propofol Attenuates Hypoxia/Reoxygenation-Induced Apoptosis and Autophagy in HK-2 Cells by Inhibiting JNK Activation.
Effect of hydrogen-rich water on the Nrf2/ARE signaling pathway in rats with myocardial ischemia-reperfusion injury.
Molecular mechanism of miR-204 regulates proliferation, apoptosis and autophagy of cervical cancer cells by targeting ATF2.
Osteoadherin serves roles in the regulation of apoptosis and growth in MC3T3‑E1 osteoblast cells.
Bexarotene Attenuates Focal Cerebral Ischemia-Reperfusion Injury via the Suppression of JNK/Caspase-3 Signaling Pathway.
Design, synthesis and molecular mechanisms of novel dual inhibitors of heat shock protein 90/phosphoinositide 3-kinase alpha (Hsp90/PI3Kα) against cutaneous melanoma.
Silencing ubiquitin-conjugating enzyme 2C inhibits proliferation and epithelial-mesenchymal transition in pancreatic ductal adenocarcinoma.
Hepatoprotective effects of zinc (II) via cytochrome P-450/reactive oxygen species and canonical apoptosis pathways after arsenite waterborne exposure in common carp.
CircRhoC promotes tumorigenicity and progression in ovarian cancer by functioning as a miR-302e sponge to positively regulate VEGFA.
Protective effects of betaine on diabetic induced disruption of the male mice blood-testis barrier by regulating oxidative stress-mediated p38 MAPK pathways.
Glycogen phosphorylase B promotes ovarian cancer progression via Wnt/β-catenin signaling and is regulated by miR-133a-3p.
Differential immune responses of C57BL/6 mice to infection by Salmonella enterica serovar Typhimurium strain SL1344, CVCC541 and CMCC50115.
circPUM1 Promotes Tumorigenesis and Progression of Ovarian Cancer by Sponging miR-615-5p and miR-6753-5p.
Dietary Curcumin Supplementation Increases Antioxidant Capacity, Upregulates Nrf2 and Hmox1 Levels in the Liver of Piglet Model with Intrauterine Growth Retardation.
ATXN3 promotes breast cancer metastasis by deubiquitinating KLF4.
Autophagy Attenuation Hampers Progesterone Synthesis during the Development of Pregnant Corpus Luteum.
Dietary Dihydroartemisinin Supplementation Attenuates Hepatic Oxidative Damage of Weaned Piglets with Intrauterine Growth Retardation through the Nrf2/ARE Signaling Pathway.
LPS Inhibits Fatty Acid Absorption in Enterocytes through TNF-α Secreted by Macrophages.
Icariin targets Nrf2 signaling to inhibit microglia-mediated neuroinflammation.
Disubstituted Dithiolethione ACDT Exerts Neuroprotective Effects Against 6-Hydroxydopamine-Induced Oxidative Stress in SH-SY5Y Cells.
Abnormal serum vitamin A levels and retinoic acid receptor α expression patterns in children with anorectal malformation.
Hypoxic postconditioning activates the Wnt/β-catenin pathway and protects against transient global cerebral ischemia through Dkk1 Inhibition and GSK-3β inactivation.
Exosomes from high glucose-treated macrophages activate glomerular mesangial cells via TGF-β1/Smad3 pathway in vivo and in vitro.
Bone marrow mesenchymal stem cells could reduce the toxic effects of hexavalent chromium on the liver by decreasing endoplasmic reticulum stress-mediated apoptosis via SIRT1/HIF-1α signaling pathway in rats.
Knockdown of LncRNA SCAMP1 suppressed malignant biological behaviours of glioma cells via modulating miR-499a-5p/LMX1A/NLRC5 pathway.
RING finger protein 10 is a potential drug target for diabetic vascular complications.
Bilirubin alleviates alum-induced peritonitis through inactivation of NLRP3 inflammasome.
The expression of cerebrospinal fluid exosomal miR-630 plays an important role in the dysfunction of endothelial cells after subarachnoid hemorrhage.
Cordycepin alleviates hepatic lipid accumulation by inducing protective autophagy via PKA/mTOR pathway.
Brilliant Blue G Inhibits Inflammasome Activation and Reduces Disruption of Blood-Spinal Cord Barrier Induced by Spinal Cord Injury in Rats.
miR-205-5p regulates epithelial-mesenchymal transition by targeting PTEN via PI3K/AKT signaling pathway in cisplatin-resistant nasopharyngeal carcinoma cells.
Rho-kinase inhibitor attenuates airway mucus hypersecretion and inflammation partly by downregulation of IL-13 and the JNK1/2-AP1 signaling pathway.
Selective ERK1/2 agonists isolated from Melia azedarach with potent anti-leukemic activity.
MiR-146b accelerates osteoarthritis progression by targeting alpha-2-macroglobulin.
Identification of proteomic signatures associated with COPD frequent exacerbators.
Changes among TGF-β1+ Breg cells and helper T cell subsets in a murine model of allergic rhinitis with prolonged OVA challenge.
CD36 plays a negative role in the regulation of lipophagy in hepatocytes through an AMPK-dependent pathway.
Simvastatin ameliorates total liver ischemia/reperfusion injury via KLF2-mediated mechanism in rats.
High-mobility group box 1 protein modulated proliferation and radioresistance in esophageal squamous cell carcinoma.
Nicotinate-curcumin ameliorates cognitive impairment in diabetic rats by rescuing autophagic flux in CA1 hippocampus.
CCL18 promotes the metastasis of squamous cell carcinoma of the head and neck through MTDH-NF-κB signalling pathway.
SIRT5-mediated SDHA desuccinylation promotes clear cell renal cell carcinoma tumorigenesis.
Changes in the levels of 12/15-lipoxygenase, apoptosis-related proteins and inflammatory factors in the cortex of diabetic rats and the neuroprotection of baicalein.
The toxicity of multi-walled carbon nanotubes (MWCNTs) to human endothelial cells: The influence of diameters of MWCNTs.
Effects of myostatin deficiency on PGC-1α and FNDC5 expression in three different murine muscle types.
Prolonged high-glucose exposure decreased SREBP-1/FASN/ACC in Schwann cells of diabetic mice via blocking PI3K/Akt pathway.
MiRNA-29a modulates visceral hyperalgesia in irritable bowel syndrome by targeting HTR7.
Long non-coding RNA GBCDRlnc1 induces chemoresistance of gallbladder cancer cells by activating autophagy.
The Anticonvulsant Effects of Baldrinal on Pilocarpine-Induced convulsion in Adult Male Mice.
Effects of agomelatine in rotenone-induced Parkinson's disease in rats.
Ginsenoside Rk1 induces cell cycle arrest and apoptosis in MDA-MB-231 triple negative breast cancer cells.
The effect of di-2-ethylhexyl phthalate on inflammation and lipid metabolic disorder in rats.
Transketolase (TKT) activity and nuclear localization promote hepatocellular carcinoma in a metabolic and a non-metabolic manner.
Microglial NLRP3 inflammasome activation mediates IL-1β release and contributes to central sensitization in a recurrent nitroglycerin-induced migraine model.
TCF7L1 indicates prognosis and promotes proliferation through activation of Keap1/NRF2 in gastric cancer.
Inhibition of soluble epoxide hydrolase ameliorates hyperhomocysteinemia-induced hepatic steatosis by enhancing β-oxidation of fatty acid in mice.
High Expression of lncRNA AFAP1-AS1 Promotes the Progression of Colon Cancer and Predicts Poor Prognosis.
Trio-Based Deep Sequencing Reveals a Low Incidence of Off-Target Mutations in the Offspring of Genetically Edited Goats.
Fangchinoline Ameliorates the Expressions of Angiogenic Molecule in Cerebral Ischemia Induced Neuronal Degeneration in Neonatal Rats.
Snx27 Deletion Promotes Recovery From Spinal Cord Injury by Neuroprotection and Reduces Macrophage/Microglia Proliferation.
Adipocytes fuel gastric cancer omental metastasis via PITPNC1-mediated fatty acid metabolic reprogramming.
Th17 cell-derived IL-17A promoted tumor progression via STAT3/NF-κB/Notch1 signaling in non-small cell lung cancer.
Long Noncoding RNA HOTTIP Promotes Mouse Hepatic Stellate Cell Activation via Downregulating miR-148a.
The FOXK1-CCDC43 Axis Promotes the Invasion and Metastasis of Colorectal Cancer Cells.
Tumor-Secreted Exosomal miR-222 Promotes Tumor Progression via Regulating P27 Expression and Re-Localization in Pancreatic Cancer.
High Concentration of Aspirin Induces Apoptosis in Rat Tendon Stem Cells via Inhibition of the Wnt/β-Catenin Pathway.
Mesenchymal Stem Cell-Derived Exosomes Reduce A1 Astrocytes via Downregulation of Phosphorylated NFκB P65 Subunit in Spinal Cord Injury.
LncRNA PCGEM1 Induces Ovarian Carcinoma Tumorigenesis and Progression Through RhoA Pathway.
The influence of GAPT extraction on synapse loss of APPswe/PS1dE9 transgenic mice via adjusting Bcl-2/Bax balance.
The Potential Protective Effect of Curcumin on Amyloid-β-42 Induced Cytotoxicity in HT-22 Cells.
Ingredients from Litsea garrettii as Potential Preventive Agents against Oxidative Insult and Inflammatory Response.
Serum and Ectopic Endometrium from Women with Endometriosis Modulate Macrophage M1/M2 Polarization via the Smad2/Smad3 Pathway.
Dysfunction of Nrf2-ARE Signaling Pathway: Potential Pathogenesis in the Development of Neurocognitive Impairment in Patients with Moderate to Severe Obstructive Sleep Apnea-Hypopnea Syndrome.
Fucosterol Protects against Concanavalin A-Induced Acute Liver Injury: Focus on P38 MAPK/NF-κB Pathway Activity.
Effects of Chicory on Serum Uric Acid, Renal Function, and GLUT9 Expression in Hyperuricaemic Rats with Renal Injury and In Vitro Verification with Cells.
Necrostatin-1 promotes ectopic periodontal tissue like structure regeneration in LPS-treated PDLSCs.
Targeting MAPK Pathways by Naringenin Modulates Microglia M1/M2 Polarization in Lipopolysaccharide-Stimulated Cultures.
Arsenic sulfide amplifies JQ1 toxicity via mitochondrial pathway in gastric and colon cancer cells.
Natural antisense transcript of hypoxia-inducible factor 1 regulates hypoxic cell apoptosis in epithelial ovarian cancer.
Contribution of dysregulated circRNA_100876 to proliferation and metastasis of esophageal squamous cell carcinoma.
Combination Treatment of Icariin and L-DOPA Against 6-OHDA-Lesioned Dopamine Neurotoxicity.
Lithium chloride inhibits cell survival, overcomes drug resistance, and triggers apoptosis in multiple myeloma via activation of the Wnt/β-catenin pathway.
Leucine Carboxyl Methyltransferase Downregulation and Protein Phosphatase Methylesterase Upregulation Contribute Toward the Inhibition of Protein Phosphatase 2A by α-Synuclein.
Cdk5 Inhibitory Peptide Prevents Loss of Dopaminergic Neurons and Alleviates Behavioral Changes in an MPTP Induced Parkinson's Disease Mouse Model.
lncRNA DLEU1 contributes to tumorigenesis and development of endometrial carcinoma by targeting mTOR.
Curcumin attenuates resistance to irinotecan via induction of apoptosis of cancer stem cells in chemoresistant colon cancer cells.
MiR-20a-3p regulates TGF-β1/Survivin pathway to affect keratinocytes proliferation and apoptosis by targeting SFMBT1 in vitro.
Resveratrol relieves particulate matter (mean diameter < 2.5 μm)-induced oxidative injury of lung cells through attenuation of autophagy deregulation.
Artemisitene suppresses tumorigenesis by inducing DNA damage through deregulating c-Myc-topoisomerase pathway.
Knockdown of long noncoding RNA GHET1 inhibits cell‑cycle progression and invasion of gastric cancer cells.
TAM Infiltration Differences in "Tumor-First" and " ZHENG-First" Models and the Underlying Inflammatory Molecular Mechanism in Pancreatic Cancer.
Overexpression of SMARCA2 or CAMK2D is associated with cisplatin resistance in human epithelial ovarian cancer.
Effects of SB202190 on expression levels of IL-6 and NF-κB in flap ischemia-reperfusion injury.
2',4'-Dihydroxy-6'-methoxy-3',5'-dimethylchalcone, a potent Nrf2/ARE pathway inhibitor, reverses drug resistance by decreasing glutathione synthesis and drug efflux in BEL-7402/5-FU cells.
Bexarotene protects against neurotoxicity partially through a PPARγ-dependent mechanism in mice following traumatic brain injury.
miR-383 negatively regulates osteoblastic differentiation of bone marrow mesenchymal stem cells in rats by targeting Satb2.
Oxymatrine Inhibits Transforming Growth Factor β1 (TGF-β1)-Induced Cardiac Fibroblast-to-Myofibroblast Transformation (FMT) by Mediating the Notch Signaling Pathway In Vitro.
Lactate enhanced the effect of parathyroid hormone on osteoblast differentiation via GPR81-PKC-Akt signaling.
H2A.Z.1 crosstalk with H3K56-acetylation controls gliogenesis through the transcription of folate receptor.
RING finger protein 10 prevents neointimal hyperplasia by promoting apoptosis in vitro and in vivo.
miR‑92b promotes autophagy and suppresses viability and invasion in breast cancer by targeting EZH2.
Acrolein-induced autophagy-dependent apoptosis via activation of the lysosomal-mitochondrial pathway in EAhy926 cells.
Erythropoietin Treatment Ameliorates Lupus Nephritis of MRL/lpr Mice.
Association between Tim‑3 and Gal‑9 expression and gastric cancer prognosis.
Low-Dose Radiation Enhanced Inhibition of Breast Tumor Xenograft and Reduced Myocardial Injury Induced by Doxorubicin.
High expression of WNT7A predicts poor prognosis and promote tumor metastasis in pancreatic ductal adenocarcinoma.
Construction of a High-Efficiency Drug and Gene Co-Delivery System for Cancer Therapy from a pH-Sensitive Supramolecular Inclusion between Oligoethylenimine- graft-β-cyclodextrin and Hyperbranched Polyglycerol Derivative.
ERα is a negative regulator of PD-L1 gene transcription in breast cancer.
Temozolomide-Perillyl alcohol conjugate impairs Mitophagy flux by inducing lysosomal dysfunction in non-small cell lung Cancer cells and sensitizes them to irradiation.
CNTNAP4 Impacts Epilepsy Through GABAA Receptors Regulation: Evidence From Temporal Lobe Epilepsy Patients and Mouse Models.
Cold-induced protein RBM3 orchestrates neurogenesis via modulating Yap mRNA stability in cold stress.
BF211, a derivative of bufalin, enhances the cytocidal effects in multiple myeloma cells by inhibiting the IL-6/JAK2/STAT3 pathway.
FGF9 modulates Schwann cell myelination in developing nerves and induces a pro-inflammatory environment during injury.
Pyroptosis of HUVECs can be induced by heat stroke.
Luteolin sensitizes the antitumor effect of cisplatin in drug-resistant ovarian cancer via induction of apoptosis and inhibition of cell migration and invasion.
Lysyl oxidase blockade ameliorates anovulation in polycystic ovary syndrome.
Decrease of galectin-3 in keratinocytes: A potential diagnostic marker and a critical contributor to the pathogenesis of psoriasis.
The inhibitory effect in Fraxinellone on oxidative stress-induced senescence correlates with AMP-activated protein kinase-dependent autophagy restoration.
PD-L1 confers glioblastoma multiforme malignancy via Ras binding and Ras/Erk/EMT activation.
Reversing Multidrug Resistance by Multiplexed Gene Silencing for Enhanced Breast Cancer Chemotherapy.
Oxyresveratrol prevents lipopolysaccharide/d-galactosamine-induced acute liver injury in mice.
Donor Treatment With a Hypoxia-Inducible Factor-1 Agonist Prevents Donation After Cardiac Death Liver Graft Injury in a Rat Isolated Perfusion Model.
Proteomics analysis of altered proteins in kidney of mice with aristolochic acid nephropathy using the fluorogenic derivatization-liquid chromatography-tandem mass spectrometry method.
Expression of diaphragmatic myostatin and correlation with apoptosis in rats with chronic obstructive pulmonary disease.
Lipoxin A4 improves erectile dysfunction in rats with type I diabetes by inhibiting oxidative stress and corporal fibrosis.
Marine Bacterial Polysaccharide EPS11 Inhibits Cancer Cell Growth via Blocking Cell Adhesion and Stimulating Anoikis.
AMPK alleviates endoplasmic reticulum stress by inducing the ER-chaperone ORP150 via FOXO1 to protect human bronchial cells from apoptosis.
7-Acetylsinumaximol B Induces Apoptosis and Autophagy in Human Gastric Carcinoma Cells through Mitochondria Dysfunction and Activation of the PERK/eIF2α/ATF4/CHOP Signaling Pathway.
In vitro inhibition of porcine reproductive and respiratory syndrome virus replication by short antisense oligonucleotides with locked nucleic acid modification.
Epidermal Growth Factor, through Alleviating Oxidative Stress, Protect IPEC-J2 Cells from Lipopolysaccharides-Induced Apoptosis.
Early Postnatal Exposure to Airborne Fine Particulate Matter Induces Autism-like Phenotypes in Male Rats.
All-Trans Retinoic Acid Ameliorates the Early Experimental Cerebral Ischemia-Reperfusion Injury in Rats by Inhibiting the Loss of the Blood-Brain Barrier via the JNK/P38MAPK Signaling Pathway.
Formononetin inhibits colon carcinoma cell growth and invasion by microRNA‑149‑mediated EphB3 downregulation and inhibition of PI3K/AKT and STAT3 signaling pathways.
Expression of tumor suppressor programmed cell death 4 in endometrioid endometrial carcinomas and clinicopathological significance.
FPOA induces apoptosis in HeLa human cervical cancer cells through a caspase-mediated pathway.
Pseudo-Ginsenoside Rh2 induces A549 cells apoptosis via the Ras/Raf/ERK/p53 pathway.
Effects of Tumor Necrosis Factor α (TNF-α) and Interleukina 10 (IL-10) on Intercellular Cell Adhesion Molecule-1 (ICAM-1) and Cluster of Differentiation 31 (CD31) in Human Coronary Artery Endothelial Cells.
Chronic cold exposure results in subcutaneous adipose tissue browning and altered global metabolism in Qinghai-Tibetan plateau pika (Ochotona curzoniae).
Regional up-regulation of NOX2 contributes to the differential vulnerability of outer hair cells to neomycin.
Down-regulation of IFIT3 protects liver from ischemia-reperfusion injury.
Long non-coding RNA (lncRNA) MAGI2-AS3 inhibits breast cancer cell growth by targeting the Fas/FasL signalling pathway.
Wnt/β-catenin modulates chronic tobacco smoke exposure-induced acquisition of pulmonary cancer stem cell properties and diallyl trisulfide intervention.
Glutathione Reduction of Patulin-Evoked Cytotoxicity in HEK293 Cells by the Prevention of Oxidative Damage and the Mitochondrial Apoptotic Pathway.
Intermittent streptozotocin administration induces behavioral and pathological features relevant to Alzheimer's disease and vascular dementia.
Baicalein inhibits cervical cancer progression via downregulating long noncoding RNA BDLNR and its downstream PI3K/Akt pathway.
Activation of Nrf2 pathway and inhibition of NLRP3 inflammasome activation contribute to the protective effect of chlorogenic acid on acute liver injury.
Nitric oxide, afferent sensory nerves, and antioxidative enzymes in the mechanism of protection mediated by tricarbonyldichlororuthenium(II) dimer and sodium hydrosulfide against aspirin-induced gastric damage.
Anticancer effect of SZC015 on pancreatic cancer via mitochondria-dependent apoptosis and the constitutive suppression of activated nuclear factor κB and STAT3 in vitro and in vivo.
Thrombopoietin protects H9C2 cells from excessive autophagy and apoptosis in doxorubicin-induced cardiotoxicity.
Exogenous oxidants activate nuclear factor kappa B through Toll-like receptor 4 stimulation to maintain inflammatory phenotype in macrophage.
Experimental evidence of good efficacy and reduced toxicity with peptide-doxorubicin to treat gastric cancer.
The protective role of low-concentration alcohol in high-fructose induced adverse cardiovascular events in mice.
Nicotine Induces Progressive Properties of Lung Adenocarcinoma A549 Cells by Inhibiting Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Expression and Plasma Membrane Localization.
Effects of calycosin against high-fat diet-induced nonalcoholic fatty liver disease in mice.
Genipin alleviates high-fat diet-induced hyperlipidemia and hepatic lipid accumulation in mice via miR-142a-5p/SREBP-1c axis.
Di-(2-ethylhexyl)-phthalate induces glucose metabolic disorder in adolescent rats.
Construction and protective immunogenicity of DNA vaccine pNMB0315 against Neisseria meningitidis serogroup B.
The N-terminal ubiquitin-associated domain of Cezanne is crucial for its function to suppress NF-κB pathway.
[Impact of Cystic Fibrosis Transmembrane Conductance Regulator on Malignant Properties of KRAS Mutant Lung Adenocarcinoma A549 Cells].
RACK1 is indispensable for porcine reproductive and respiratory syndrome virus replication and NF-κB activation in Marc-145 cells.
Neuroprotective Effect of Anethole Against Neuropathic Pain Induced by Chronic Constriction Injury of the Sciatic Nerve in Mice.
Relationship of Epidermal Growth Factor Receptor Expression with Clinical Symptoms and Metastasis of Invasive Breast Cancer.
Role of Long Noncoding RNA 799 in the Metastasis of Cervical Cancer through Upregulation of TBL1XR1 Expression.
WISP1 mediates lung injury following hepatic ischemia reperfusion dependent on TLR4 in mice.
The Traditional Chinese Medicine MLC901 inhibits inflammation processes after focal cerebral ischemia.
Cancer-derived exosomal miR-25-3p promotes pre-metastatic niche formation by inducing vascular permeability and angiogenesis.
Metformin suppresses growth and adrenocorticotrophic hormone secretion in mouse pituitary corticotroph tumor AtT20 cells.
Whole-exome sequencing revealed HKDC1 as a candidate gene associated with autosomal-recessive retinitis pigmentosa.
Transcription Factor FOXO3a Is a Negative Regulator of Cytotoxicity of Fusarium mycotoxin in GES-1 Cells.
Protective effects of ginsenoside Rg1 against lipopolysaccharide/d-galactosamine-induced acute liver injury in mice through inhibiting toll-like receptor 4 signaling pathway.
Dietary eicosapentaenoic acid normalizes hippocampal omega-3 and 6 polyunsaturated fatty acid profile, attenuates glial activation and regulates BDNF function in a rodent model of neuroinflammation induced by central interleukin-1β administration.
TRPC1/3/6 inhibition attenuates the TGF-β1-induced epithelial-mesenchymal transition in gastric cancer via the Ras/Raf1/ERK signaling pathway.
Knockdown of TIPE2 increases the proliferation in lipopolysaccharide-stimulated gastric cancer cells.
Anti-inflammatory activities and potential mechanisms of phenolic acids isolated from Salvia miltiorrhiza f. alba roots in THP-1 macrophages.
Hepatic, Metabolic, and Toxicity Evaluation of Repeated Oral Administration of SnS2 Nanoflowers in Mice.
Aspm knockout ferret reveals an evolutionary mechanism governing cerebral cortical size.
CHOP induces apoptosis by affecting brain iron metabolism in rats with subarachnoid hemorrhage.
Regulation on SIRT1-PGC-1α/Nrf2 pathway together with selective inhibition of aldose reductase makes compound hr5F a potential agent for the treatment of diabetic complications.
DL-3-n-butylphthalide alleviates vascular cognitive impairment induced by chronic cerebral hypoperfusion by activating the Akt/Nrf2 signaling pathway in the hippocampus of rats.
Novel decellularized liver matrix-alginate hybrid gel beads for the 3D culture of hepatocellular carcinoma cells.
Volatile Oil from Amomi Fructus Attenuates 5-Fluorouracil-Induced Intestinal Mucositis.
Inhibition of the TRPM2 and TRPV1 Channels through Hypericum perforatum in Sciatic Nerve Injury-induced Rats Demonstrates their Key Role in Apoptosis and Mitochondrial Oxidative Stress of Sciatic Nerve and Dorsal Root Ganglion.
Whole exome-wide association study identifies a missense variant in SLC2A4RG associated with glioblastoma risk.
Inhibition of HIF-1α by PX-478 suppresses tumor growth of esophageal squamous cell cancer in vitro and in vivo.
Rosiglitazone Inhibits Angiotensin II-Induced Proliferation of Glomerular Mesangial Cells via the Gαq/Plcβ4/TRPC Signaling Pathway.
Chondroprotective Effects and Multitarget Mechanisms of Fu Yuan Capsule in a Rat Osteoarthritis Model.
Electroacupuncture Improved Hippocampal Neurogenesis following Traumatic Brain Injury in Mice through Inhibition of TLR4 Signaling Pathway.
Pretreatment Donors after Circulatory Death with Simvastatin Alleviates Liver Ischemia Reperfusion Injury through a KLF2-Dependent Mechanism in Rat.
Differential inhibition of activity, activation and gene expression of MMP-9 in THP-1 cells by azithromycin and minocycline versus bortezomib: A comparative study.
Hyperlipidemia impairs erectile function in rats by causing cavernosal fibrosis.
Histone variant H3.3 orchestrates neural stem cell differentiation in the developing brain.
Exosomes derived from bone marrow stromal cells decrease the sensitivity of leukemic cells to etoposide.
Roux-en-Y gastric bypass surgery suppresses hypothalamic PTP1B protein level and alleviates leptin resistance in obese rats.
Low Frequency Magnetic Fields Induce Autophagy-associated Cell Death in Lung Cancer through miR-486-mediated Inhibition of Akt/mTOR Signaling Pathway.
AMPK activation-dependent autophagy compromises oleanolic acid-induced cytotoxicity in human bladder cancer cells.
Role of autophagy in cadmium-induced testicular injury.
Effects of hydrogen sulfide on inducible nitric oxide synthase activity and expression of cardiomyocytes in diabetic rats.
Antiplatelet drug ticagrelor delays gastric ulcer healing in rats.
HOTAIR regulates HK2 expression by binding endogenous miR-125 and miR-143 in oesophageal squamous cell carcinoma progression.
Functional characterization of a novel transcript of ERCC1 in chemotherapy resistance of ovarian cancer.
A novel protein derived from lamprey supraneural body tissue with efficient cytocidal actions against tumor cells.
LINC00461, a long non-coding RNA, is important for the proliferation and migration of glioma cells.
A high-fat, high-protein diet attenuates the negative impact of casein-induced chronic inflammation on testicular steroidogenesis and sperm parameters in adult mice.
Neuroprotective effect of liquiritin against neuropathic pain induced by chronic constriction injury of the sciatic nerve in mice.
Hepatoprotective effect of quercetin against LPS/d-GalN induced acute liver injury in mice by inhibiting the IKK/NF-κB and MAPK signal pathways.
Neuroprotective Effect of Chitosan Oligosaccharide on Hypoxic-Ischemic Brain Damage in Neonatal Rats.
CMIP is oncogenic in human gastric cancer cells.
Dlitiazem inhibits the oxidative stress induced by angiotensin II through growth hormone secretagogue receptor type 1a in human umbilicus vein endothelial cells.
Protective effects of aloperine on monocrotaline-induced pulmonary hypertension in rats.
ApoA-I/SR-BI modulates S1P/S1PR2-mediated inflammation through the PI3K/Akt signaling pathway in HUVECs.
Up-regulated BAFF and BAFF receptor expression in patients with intractable temporal lobe epilepsy and a pilocarpine-induced epilepsy rat model.
β-Caryophyllene Pretreatment Alleviates Focal Cerebral Ischemia-Reperfusion Injury by Activating PI3K/Akt Signaling Pathway.
AGR2 ameliorates tumor necrosis factor-α-induced epithelial barrier dysfunction via suppression of NF-κB p65-mediated MLCK/p-MLC pathway activation.
Relationship between abnormal TOX3 gene methylation and polycystic ovarian syndrome.
Icariin inhibits MMP‑1, MMP‑3 and MMP‑13 expression through MAPK pathways in IL‑1β‑stimulated SW1353 chondrosarcoma cells.
A novel role of fragile X mental retardation protein in pre-mRNA alternative splicing through RNA-binding protein 14.
PLAA Mutations Cause a Lethal Infantile Epileptic Encephalopathy by Disrupting Ubiquitin-Mediated Endolysosomal Degradation of Synaptic Proteins.
The Long Noncoding RNA NEAT1 Exerts Antihantaviral Effects by Acting as Positive Feedback for RIG-I Signaling.
The Anticonvulsant and Neuroprotective Effects of Oxysophocarpine on Pilocarpine-Induced Convulsions in Adult Male Mice.
KIAA1199 is induced by inflammation and enhances malignant phenotype in pancreatic cancer.
Generation and characteristics of human Sertoli cell line immortalized by overexpression of human telomerase.
Beneficial effects of Lycium barbarum polysaccharide on spermatogenesis by improving antioxidant activity and inhibiting apoptosis in streptozotocin-induced diabetic male mice.
Mitochondrial dynamics changes with age in an APPsw/PS1dE9 mouse model of Alzheimer's disease.
HMGB1-induced autophagy: a new pathway to maintain Treg function during chronic hepatitis B virus infection.
TGF-β1 promotes human hepatic carcinoma HepG2 cells invasion by upregulating autophagy.
DDX50 inhibits the replication of dengue virus 2 by upregulating IFN-β production.
Generation and characterization of induced pluripotent stem cells from guinea pig fetal fibroblasts.
Esculetin induces apoptosis of SMMC-7721 cells through IGF-1/PI3K/Akt-mediated mitochondrial pathways.
Estrogen receptor-α36 is involved in icaritin induced growth inhibition of triple-negative breast cancer cells.
Nrf2-Knockout Protects from Intestinal Injuries in C57BL/6J Mice Following Abdominal Irradiation with γ Rays.
Hypoxia-inducible factor-1 alpha is involved in RIP-induced necroptosis caused by in vitro and in vivo ischemic brain injury.
SHIP, a novel factor to ameliorate extracellular matrix accumulation via suppressing PI3K/Akt/CTGF signaling in diabetic kidney disease.
Effect of Oleracein E, a Neuroprotective Tetrahydroisoquinoline, on Rotenone-Induced Parkinson's Disease Cell and Animal Models.
BMP4 promotes mouse iPS cell differentiation to male germ cells via Smad1/5, Gata4, Id1 and Id2.
Induction of apoptosis by FFJ-5, a novel naphthoquinone compound, occurs via downregulation of PKM2 in A549 and HepG2 cells.
Coptisine from Rhizoma Coptidis Suppresses HCT-116 Cells-related Tumor Growth in vitro and in vivo.
TRIM14 regulates cell proliferation and invasion in osteosarcoma via promotion of the AKT signaling pathway.
Antitumor effects of baicalin on ovarian cancer cells through induction of cell apoptosis and inhibition of cell migration in vitro.
Chloroform extract of Hedyotis diffusa Willd inhibits viability of human colorectal cancer cells via suppression of AKT and ERK signaling pathways.
Inhibition of chemotherapy-induced apoptosis of testicular cells by squid ink polysaccharide.
Involvement of TRPM2 and TRPV1 channels on hyperalgesia, apoptosis and oxidative stress in rat fibromyalgia model: Protective role of selenium.
Inhibition of Calcineurin A by FK506 Suppresses Seizures and Reduces the Expression of GluN2B in Membrane Fraction.
miR-367 promotes tumor growth by inhibiting FBXW7 in NSCLC.
Melatonin ameliorates restraint stress-induced oxidative stress and apoptosis in testicular cells via NF-κB/iNOS and Nrf2/ HO-1 signaling pathway.
Epigallocatechin-3-gallate inhibits H2O2-induced apoptosis in Mouse Vascular Smooth Muscle Cells via 67kD Laminin Receptor.
Phosphocreatine protects endothelial cells from Methylglyoxal induced oxidative stress and apoptosis via the regulation of PI3K/Akt/eNOS and NF-κB pathway.
Long non-coding RNA TUG1 promotes cell proliferation and metastasis by negatively regulating miR-300 in gallbladder carcinoma.
The Circadian Gene Clock Regulates Bone Formation Via PDIA3.
Terrein performs antitumor functions on esophageal cancer cells by inhibiting cell proliferation and synergistic interaction with cisplatin.
miR-150 is downregulated in osteosarcoma and suppresses cell proliferation, migration and invasion by targeting ROCK1.
Boschniakia Rossica Polysaccharide Triggers Laryngeal Carcinoma Cell Apoptosis by Regulating Expression of Bcl-2, Caspase-3, and P53.
Tumor-associated macrophages promote Ezrin phosphorylation-mediated epithelial-mesenchymal transition in lung adenocarcinoma through FUT4/LeY up-regulation.
The acute exposure of tetrachloro-p-benzoquinone (a.k.a. chloranil) triggers inflammation and neurological dysfunction via Toll-like receptor 4 signaling: The protective role of melatonin preconditioning.
1,2-Dichloroethane impairs glucose and lipid homeostasis in the livers of NIH Swiss mice.
High-dose irradiation in combination with toll-like receptor 9 agonist CpG oligodeoxynucleotide 7909 downregulates PD-L1 expression via the NF-κB signaling pathway in non-small cell lung cancer cells.
Radiation promotes epithelial-to-mesenchymal transition and invasion of pancreatic cancer cell by activating carcinoma-associated fibroblasts.
Targeting Dynamin 2 as a Novel Pathway to Inhibit Cardiomyocyte Apoptosis Following Oxidative Stress.
N-Methyl-D-aspartate Receptor Excessive Activation Inhibited Fetal Rat Lung Development In Vivo and In Vitro.
The Generation and Characterization of Recombinant Protein and Antibodies of Clostridium perfringens Beta2 Toxin.
Quantitative Proteomic Profiling the Molecular Signatures of Annexin A5 in Lung Squamous Carcinoma Cells.
The long noncoding RNA MALAT1 regulates the lipopolysaccharide-induced inflammatory response through its interaction with NF-κB.
Lactobacillus rhamnosus induced epithelial cell apoptosis, ameliorates inflammation and prevents colon cancer development in an animal model.
Hydrogen Sulfide and Carbon Monoxide Protect Gastric Mucosa Compromised by Mild Stress Against Alendronate Injury.
Quantitative proteomics reveals molecular mechanism of gamabufotalin and its potential inhibition on Hsp90 in lung cancer.
Progranulin deficiency leads to severe inflammation, lung injury and cell death in a mouse model of endotoxic shock.
The tumor suppressor PTEN has a critical role in antiviral innate immunity.
AMPK-mediated up-regulation of mTORC2 and MCL-1 compromises the anti-cancer effects of aspirin.
Potassium supplementation inhibits IL-17A production induced by salt loading in human T lymphocytes via p38/MAPK-SGK1 pathway.
Myricetin ameliorates brain injury and neurological deficits via Nrf2 activation after experimental stroke in middle-aged rats.
Carboxy-terminal modulator protein attenuated extracellular matrix deposit by inhibiting phospho-Akt, TGF-β1 and α-SMA in kidneys of diabetic mice.
Lipodystrophy and severe metabolic dysfunction in mice with adipose tissue-specific insulin receptor ablation.
miR-223 enhances the sensitivity of non-small cell lung cancer cells to erlotinib by targeting the insulin-like growth factor-1 receptor.
Development of a Biomimetic Chondroitin Sulfate-modified Hydrogel to Enhance the Metastasis of Tumor Cells.
Novel Recombinant Protein FlaA N/C Protects against Radiation Injury via NF-κB Signaling.
[Corrigendum] Cannabinoid WIN55, 212-2 induces cell cycle arrest and inhibits the proliferation and migration of human BEL7402 hepatocellular carcinoma cells.
Gamabufotalin, a major derivative of bufadienolide, inhibits VEGF-induced angiogenesis by suppressing VEGFR-2 signaling pathway.
Bezafibrate-mizoribine interaction: Involvement of organic anion transporters OAT1 and OAT3 in rats.
Nicotine Induced Murine Spermatozoa Apoptosis via Up-Regulation of Deubiquitinated RIP1 by Trim27 Promoter Hypomethylation.
IL-17 intensifies IFN-γ-induced NOS2 upregulation in RAW 264.7 cells by further activating STAT1 and NF-κB.
Effect of acute lipopolysaccharide-induced inflammation in intracerebroventricular-streptozotocin injected rats.
ApoA-I induces S1P release from endothelial cells through ABCA1 and SR-BI in a positive feedback manner.
Establishment of a first-line second-line treatment model for human pulmonary adenocarcinoma.
Interaction between endogenous carbon monoxide and hydrogen sulfide in the mechanism of gastroprotection against acute aspirin-induced gastric damage.
Anti-tumor effects of osthole on ovarian cancer cells in vitro.
Casitas B-cell lymphoma (Cbl) proteins protect mammary epithelial cells from proteotoxicity of active c-Src accumulation.
State estimation and prediction using clustered particle filters.
Disrupting MALAT1/miR-200c sponge decreases invasion and migration in endometrioid endometrial carcinoma.
miR-1273g-3p modulates activation and apoptosis of hepatic stellate cells by directly targeting PTEN in HCV-related liver fibrosis.
MiR-770-5p inhibits cisplatin chemoresistance in human ovarian cancer by targeting ERCC2.
Calcium efflux from the endoplasmic reticulum regulates cisplatin-induced apoptosis in human cervical cancer HeLa cells.
Highly expressed UNC119 promotes hepatocellular carcinoma cell proliferation through Wnt/β-catenin signaling and predicts a poor prognosis.
Study on the Dynamic Biological Characteristics of Sca-1(+) Hematopoietic Stem and Progenitor Cell Senescence.
Liquiritigenin Protects Rats from Carbon Tetrachloride Induced Hepatic Injury through PGC-1α Pathway.
MYBL2 guides autophagy suppressor VDAC2 in the developing ovary to inhibit autophagy through a complex of VDAC2-BECN1-BCL2L1 in mammals.
Panaxadiol Saponin and Dexamethasone Improve Renal Function in Lipopolysaccharide-Induced Mouse Model of Acute Kidney Injury.
The Nucleocapsid Protein of Coronaviruses Acts as a Viral Suppressor of RNA Silencing in Mammalian Cells.
FUS Interacts with HSP60 to Promote Mitochondrial Damage.
Exposure to airborne PM2.5 suppresses microRNA expression and deregulates target oncogenes that cause neoplastic transformation in NIH3T3 cells.
HBx-related long non-coding RNA DBH-AS1 promotes cell proliferation and survival by activating MAPK signaling in hepatocellular carcinoma.
Olaquindox induces DNA damage via the lysosomal and mitochondrial pathway involving ROS production and p53 activation in HEK293 cells.
Inhibition of migration and induction of apoptosis in LoVo human colon cancer cells by polysaccharides from Ganoderma lucidum.
Establishment and Characterization of Human Germline Stem Cell Line with Unlimited Proliferation Potentials and no Tumor Formation.
A Critical Role for Cysteine 57 in the Biological Functions of Selenium Binding Protein-1.
MicroRNA-206 attenuates tumor proliferation and migration involving the downregulation of NOTCH3 in colorectal cancer.
Reactive stroma component COL6A1 is upregulated in castration-resistant prostate cancer and promotes tumor growth.
Tetrachlorobenzoquinone triggers the cleavage of Bid and promotes the cross-talk of extrinsic and intrinsic apoptotic signalings in pheochromocytoma (PC) 12 cells.
Trophoblast glycoprotein promotes pancreatic ductal adenocarcinoma cell metastasis through Wnt/planar cell polarity signaling.
The safety and anti-hypercholesterolemic effect of coptisine in Syrian golden hamsters.
SPAG6 silencing inhibits the growth of the malignant myeloid cell lines SKM-1 and K562 via activating p53 and caspase activation-dependent apoptosis.
Artificial sweetener neohesperidin dihydrochalcone showed antioxidative, anti-inflammatory and anti-apoptosis effects against paraquat-induced liver injury in mice.
Dynamic expression of miR-206-3p during mouse skin development is independent of keratinocyte differentiation.
Cannabinoid WIN55, 212-2 induces cell cycle arrest and inhibits the proliferation and migration of human BEL7402 hepatocellular carcinoma cells.
miR-140-5p regulates adipocyte differentiation by targeting transforming growth factor-β signaling.
Postnatal alterations in GABAB receptor tone produce sensorimotor gating deficits and protein level differences in adulthood.
RAD51B Activity and Cell Cycle Regulation in Response to DNA Damage in Breast Cancer Cell Lines.
Inhibition of 15-lipoxygenase (15-LOX) reverses hypoxia-induced down-regulation of potassium channels Kv1.5 and Kv2.1Inhibition of 15-lipoxygenase (15-LOX) reverses hypoxia-induced down-regulation of potassium channels Kv1.5 and Kv2.1.
Role of α-lipoic acid in LPS/d-GalN induced fulminant hepatic failure in mice: studies on oxidative stress, inflammation and apoptosis.
Identification and validation of a novel microRNA-like molecule derived from a cytoplasmic RNA virus antigenome by bioinformatics and experimental approaches.
Edwardsiella tarda-Induced cytotoxicity depends on its type III secretion system and flagellin.
Integrative genomics in combination with RNA interference identifies prognostic and functionally relevant gene targets for oral squamous cell carcinoma.
Calpain mediates caspase-dependent apoptosis initiated by hydrogen peroxide in pancreatic acinar AR42J cells.
The hepatitis B virus X protein downregulates NF-κB signaling pathways through decreasing the Notch signaling pathway in HBx-transformed L02 cells.
Limb-girdle muscular dystrophy 1F is caused by a microdeletion in the transportin 3 gene.
Cytohesin-2 as a novel prognostic marker for hepatocellular carcinoma.
Roles of 3,4-methylenedioxymethamphetamine (MDMA)-induced alteration of connexin43 and intracellular Ca(2+) oscillation in its cardiotoxicity.
Jiang Y, Li H, Huang P, Li S, Li B, Huo L, Zhong J, Pan Z, Li Y, Xia X
Journal of ethnopharmacology 2022 Mar 1;285:114859
Journal of ethnopharmacology 2022 Mar 1;285:114859
Protocatechuic aldehyde prevents ischemic injury by attenuating brain microvascular endothelial cell pyroptosis via lncRNA Xist.
Guo Y, Yang JH, He Y, Zhou HF, Wang Y, Ding ZS, Jin B, Wan HT
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jan;94:153849
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jan;94:153849
Hydrogen sulphide attenuates neuronal apoptosis of substantia nigra by re-establishing autophagic flux via promoting leptin signalling in a 6-hydroxydopamine rat model of Parkinson's disease.
Jiang W, Zou W, Hu M, Tian Q, Xiao F, Li M, Zhang P, Chen YJ, Jiang JM
Clinical and experimental pharmacology & physiology 2022 Jan;49(1):122-133
Clinical and experimental pharmacology & physiology 2022 Jan;49(1):122-133
Dihydroartemisinin attenuates osteoclast formation and bone resorption via inhibiting the NF‑κB, MAPK and NFATc1 signaling pathways and alleviates osteoarthritis.
Ding D, Yan J, Feng G, Zhou Y, Ma L, Jin Q
International journal of molecular medicine 2022 Jan;49(1)
International journal of molecular medicine 2022 Jan;49(1)
Corilagin induces apoptosis and inhibits autophagy of HL‑60 cells by regulating miR‑451/HMGB1 axis.
Jia S, He D, Liang X, Cheng P, Liu J, Chen M, Wang C, Zhang H, Meng C
Molecular medicine reports 2022 Jan;25(1)
Molecular medicine reports 2022 Jan;25(1)
Jujuboside A ameliorates high fat diet and streptozotocin induced diabetic nephropathy via suppressing oxidative stress, apoptosis, and enhancing autophagy.
Zhong Y, Luo R, Liu Q, Zhu J, Lei M, Liang X, Wang X, Peng X
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2022 Jan;159:112697
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2022 Jan;159:112697
Adaptation to partial urethral obstruction in healthy aging LOU rats and the role of nerve growth factor signaling pathway in the bladder.
Mossa A, Cammisotto PG, Velasquez-Flores M, Campeau L
Experimental gerontology 2022 Jan;157:111625
Experimental gerontology 2022 Jan;157:111625
Overexpression of sFlt-1 represses ox-LDL-induced injury of HUVECs by activating autophagy via PI3K/AKT/mTOR pathway.
Zhou YH, Tang YZ, Guo LY, Zheng LL, Zhang D, Yang CY, Wang W
Microvascular research 2022 Jan;139:104252
Microvascular research 2022 Jan;139:104252
Dihydroartemisinin represses oral squamous cell carcinoma progression through downregulating mitochondrial calcium uniporter.
Zheng S, Wu R, Deng Y, Zhang Q
Bioengineered 2022 Jan;13(1):227-241
Bioengineered 2022 Jan;13(1):227-241
Inhibition of CDK1 attenuates neuronal apoptosis and autophagy and confers neuroprotection after chronic spinal cord injury in vivo.
Nie BX, Zhao G, Yuan XF, Yu LX, Zhang J, Yuan Y, Liu Y, Hu J, Song E, Zhou YC, Shu J
Journal of chemical neuroanatomy 2022 Jan;119:102053
Journal of chemical neuroanatomy 2022 Jan;119:102053
An in vitro senescence model of gingival epithelial cell induced by hydrogen peroxide treatment.
Giri S, Takada A, Paudel D, Yoshida K, Furukawa M, Kuramitsu Y, Matsushita K, Abiko Y, Furuichi Y
Odontology 2022 Jan;110(1):44-53
Odontology 2022 Jan;110(1):44-53
The role of regulatory T cells on the activation of astrocytes in the brain of high-fat diet mice following lead exposure.
Wu L, Li S, Li C, He B, Lv L, Wang J, Wang J, Wang W, Zhang Y
Chemico-biological interactions 2022 Jan 5;351:109740
Chemico-biological interactions 2022 Jan 5;351:109740
FSH inhibits autophagy and lysosomal biogenesis to regulate protein degradation in cultured goat Sertoli cells.
Xi H, Ren F, Li Y, Xian M, Wang L, Hu J
Molecular and cellular endocrinology 2022 Jan 15;540:111505
Molecular and cellular endocrinology 2022 Jan 15;540:111505
In vitro and in silico anti-osteoporosis activities and underlying mechanisms of a fructan, ABW90-1, from Achyranthes bidentate.
Li T, Hou X, Huang Y, Wang C, Chen H, Yan C
Carbohydrate polymers 2022 Jan 15;276:118730
Carbohydrate polymers 2022 Jan 15;276:118730
Xiaoyao powder improves endometrial receptivity via VEGFR-2-mediated angiogenesis through the activation of the JNK and P38 signaling pathways.
He M, Li L, Wei X, Geng D, Jiang H, Xiangxiang G, Zhang Y, Du H
Journal of ethnopharmacology 2022 Jan 10;282:114580
Journal of ethnopharmacology 2022 Jan 10;282:114580
125I seeds inhibit proliferation and promote apoptosis in cholangiocarcinoma cells by regulating the AGR2-mediated p38 MAPK pathway.
Zhou X, Zhang W, Dou M, Li Z, Liu Z, Li J, Tian C, Yao Y, Wang C, Li Y, Chen P, Han X, Jiao D
Cancer letters 2022 Jan 1;524:29-41
Cancer letters 2022 Jan 1;524:29-41
TiO2 nanosheets promote the transformation of vascular smooth muscle cells into foam cells in vitro and in vivo through the up-regulation of nuclear factor kappa B subunit 2.
Li S, Yan D, Huang C, Yang F, Cao Y
Journal of hazardous materials 2022 Feb 15;424(Pt D):127704
Journal of hazardous materials 2022 Feb 15;424(Pt D):127704
Inhibition of Kelch-like epichlorohydrin-related protein 1 promotes the progression and drug resistance of lung adenocarcinoma.
Gao H, Tang P, Ni K, Zhu L, Chen S, Zheng Y, Wan Y
PeerJ 2021;9:e11908
PeerJ 2021;9:e11908
Combination of ferulic acid, ligustrazine and tetrahydropalmatine inhibits invasion and metastasis through MMP/TIMP signaling in endometriosis.
Tan Y, Zhang C, Zhang Y, Dai X, Wei Q, Wei J, Xu P, Chen Y
PeerJ 2021;9:e11664
PeerJ 2021;9:e11664
CTRP1 Attenuates Cerebral Ischemia/Reperfusion Injury via the PERK Signaling Pathway.
Fei H, Xiang P, Luo W, Tan X, Gu C, Liu M, Chen M, Wang Q, Yang J
Frontiers in cell and developmental biology 2021;9:700854
Frontiers in cell and developmental biology 2021;9:700854
Targeted Deletion of Loxl3 by Col2a1-Cre Leads to Progressive Hearing Loss.
Liu Z, Bai X, Wan P, Mo F, Chen G, Zhang J, Gao J
Frontiers in cell and developmental biology 2021;9:683495
Frontiers in cell and developmental biology 2021;9:683495
Osteopontin N-Terminal Function in an Abdominal Aortic Aneurysm From Apolipoprotein E-Deficient Mice.
Liu H, Zhang Y, Song W, Sun Y, Jiang Y
Frontiers in cell and developmental biology 2021;9:681790
Frontiers in cell and developmental biology 2021;9:681790
Estrogen Receptor α Mediates Doxorubicin Sensitivity in Breast Cancer Cells by Regulating E-Cadherin.
Wan X, Hou J, Liu S, Zhang Y, Li W, Zhang Y, Ding Y
Frontiers in cell and developmental biology 2021;9:583572
Frontiers in cell and developmental biology 2021;9:583572
RhoA/ROCK-YAP/TAZ Axis Regulates the Fibrotic Activity in Dexamethasone-Treated Human Trabecular Meshwork Cells.
Liu Z, Li S, Qian X, Li L, Zhang H, Liu Z
Frontiers in molecular biosciences 2021;8:728932
Frontiers in molecular biosciences 2021;8:728932
Transcriptome Differences in Pig Tracheal Epithelial Cells in Response to Pasteurella Multocida Infection.
Wang X, Wang F, Lin L, Liang W, Liu S, Hua L, Wang X, Chen H, Peng Z, Wu B
Frontiers in veterinary science 2021;8:682514
Frontiers in veterinary science 2021;8:682514
Indoleamine-2,3-Dioxygenase Activates Wnt/β-Catenin Inducing Kidney Fibrosis after Acute Kidney Injury.
Pan B, Zhang H, Hong Y, Ma M, Wan X, Cao C
Gerontology 2021;67(5):611-619
Gerontology 2021;67(5):611-619
Transient Receptor Potential Melastatin 7 Promotes Vascular Adventitial Fibroblasts Phenotypic Transformation and Inflammatory Reaction Induced by Mechanical Stretching Stress via p38 MAPK/JNK Pathway.
Liu J, Chen L, Huang J, Guo S, Zhu D, Gao P
Journal of vascular research 2021;58(2):108-120
Journal of vascular research 2021;58(2):108-120
Study on Protection of Human Umbilical Vein Endothelial Cells from Amiodarone-Induced Damage by Intermedin through Activation of Wnt/β-Catenin Signaling Pathway.
Wang Y, Wang J, Yang J, Kang J, Xue F, Chang S, Ji H, Zang H, Zhou X, Wang G, Fan W, Yan X, Guo J, Ren X, Tian J
Oxidative medicine and cellular longevity 2021;2021:8889408
Oxidative medicine and cellular longevity 2021;2021:8889408
Secretagogin Mediates the Regulatory Effect of Electroacupuncture on Hypothalamic-Pituitary-Adrenal Axis Dysfunction in Surgical Trauma.
Zhang M, Sun J, Wang Y, Tian Z
Neural plasticity 2021;2021:8881136
Neural plasticity 2021;2021:8881136
Human Tissue Kallikrein 1 Is Downregulated in Elderly Human Prostates and Possesses Potential In Vitro Antioxidative and Antifibrotic Effects in Rodent Prostates.
Zhang M, Luo C, Lin D, Cui K, Chen Z, Liu J
Oxidative medicine and cellular longevity 2021;2021:8877540
Oxidative medicine and cellular longevity 2021;2021:8877540
The Formation of Melanocyte Apoptotic Bodies in Vitiligo and the Relocation of Vitiligo Autoantigens under Oxidative Stress.
Tian J, Wang Y, Ding M, Zhang Y, Chi J, Wang T, Jiao B, Jian Z, Yi X, Huang Y, Liu L, Li K, Chen J, Wang G, Gao T, Li C, Li Q
Oxidative medicine and cellular longevity 2021;2021:7617839
Oxidative medicine and cellular longevity 2021;2021:7617839
HMSC-Derived Exosome Inhibited Th2 Cell Differentiation via Regulating miR-146a-5p/SERPINB2 Pathway.
Zhou J, Lu Y, Wu W, Feng Y
Journal of immunology research 2021;2021:6696525
Journal of immunology research 2021;2021:6696525
MCU That Is Transcriptionally Regulated by Nrf2 Augments Malignant Biological Behaviors in Oral Squamous Cell Carcinoma Cells.
Wu R, Zuo W, Xu X, Bi L, Zhang C, Chen H, Liu H
BioMed research international 2021;2021:6650791
BioMed research international 2021;2021:6650791
Decreased Expression of MPC2 Contributes to Aerobic Glycolysis and Colorectal Cancer Proliferation by Activating mTOR Pathway.
Kuerbanjiang M, Gu L, Xu C, Xu WT, Wen S, Xue H, Xu Q
Journal of immunology research 2021;2021:6618837
Journal of immunology research 2021;2021:6618837
Antioral Squamous Cell Carcinoma Effects of Carvacrol via Inhibiting Inflammation, Proliferation, and Migration Related to Nrf2/Keap1 Pathway.
Liu H, Xu X, Wu R, Bi L, Zhang C, Chen H, Yang Y
BioMed research international 2021;2021:6616547
BioMed research international 2021;2021:6616547
Metformin-Induced MicroRNA-34a-3p Downregulation Alleviates Senescence in Human Dental Pulp Stem Cells by Targeting CAB39 through the AMPK/mTOR Signaling Pathway.
Zhang S, Zhang R, Qiao P, Ma X, Lu R, Wang F, Li C, E L, Liu H
Stem cells international 2021;2021:6616240
Stem cells international 2021;2021:6616240
Anterior Gradient Protein 2 Promotes Mucosal Repair in Pediatric Ulcerative Colitis.
Ye X, Wu J, Li J, Wang H
BioMed research international 2021;2021:6483860
BioMed research international 2021;2021:6483860
Protective Effects of Huangqi Shengmai Yin on Type 1 Diabetes-Induced Cardiomyopathy by Improving Myocardial Lipid Metabolism.
Cao Z, Pan J, Sui X, Fang C, Li N, Huang X, Qu X, Han D
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5590623
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5590623
Exploring the Role and Mechanism of pAMPKα-Mediated Dysregulation of Brf1 and RNA Pol III Genes.
Wu T, Zhang D, Lin M, Yu L, Dai T, Li S, Yu F, Lu L, Zheng L, Zhong S
Oxidative medicine and cellular longevity 2021;2021:5554932
Oxidative medicine and cellular longevity 2021;2021:5554932
QiShenYiQi Pill Improves Myocardial Hypertrophy Caused by Pressure Overload in Rats.
Lv S, Wang Q, Wu M, Li M, Wang X, Xu L, Zhang J
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5536723
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5536723
Lycopene-Loaded Microemulsion Regulates Neurogenesis in Rats with Aβ-Induced Alzheimer's Disease Rats Based on the Wnt/β-catenin Pathway.
Ning WJ, Lv RJ, Xu N, Hou XY, Shen C, Guo YL, Fan ZY, Cao N, Liu XP
Neural plasticity 2021;2021:5519330
Neural plasticity 2021;2021:5519330
Saikosaponin D Inhibits the Proliferation and Promotes the Apoptosis of Rat Hepatic Stellate Cells by Inducing Autophagosome Formation.
Jiang H, Liu J, Zhang K, Zeng Q
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5451758
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5451758
Sesamin Protects against and Ameliorates Rat Intestinal Ischemia/Reperfusion Injury with Involvement of Activating Nrf2/HO-1/NQO1 Signaling Pathway.
Wang Y, Wen J, Almoiliqy M, Wang Y, Liu Z, Yang X, Lu X, Meng Q, Peng J, Lin Y, Sun P
Oxidative medicine and cellular longevity 2021;2021:5147069
Oxidative medicine and cellular longevity 2021;2021:5147069
ARHGEF3 Associated with Invasion, Metastasis, and Proliferation in Human Osteosarcoma.
Gong J, Tang W, Lv B, Zhang S, Fan T, Gao G, Chen D, Liu Y
BioMed research international 2021;2021:3381957
BioMed research international 2021;2021:3381957
Electroacupuncture Preconditioning Reduces Oxidative Stress in the Acute Phase of Cerebral Ischemia-Reperfusion in Rats by Regulating Iron Metabolism Pathways.
Liang R, Tang Q, Song W, Zhang M, Teng L, Kang Y, Zhu L
Evidence-based complementary and alternative medicine : eCAM 2021;2021:3056963
Evidence-based complementary and alternative medicine : eCAM 2021;2021:3056963
Curcumin Inhibits Replication of Human Parainfluenza Virus Type 3 by Affecting Viral Inclusion Body Formation.
Zhang C, Zhang K, Zang G, Chen T, Lu N, Wang S, Zhang G
BioMed research international 2021;2021:1807293
BioMed research international 2021;2021:1807293
Metformin Corrects Glucose Metabolism Reprogramming and NLRP3 Inflammasome-Induced Pyroptosis via Inhibiting the TLR4/NF-κB/PFKFB3 Signaling in Trophoblasts: Implication for a Potential Therapy of Preeclampsia.
Zhang Y, Liu W, Zhong Y, Li Q, Wu M, Yang L, Liu X, Zou L
Oxidative medicine and cellular longevity 2021;2021:1806344
Oxidative medicine and cellular longevity 2021;2021:1806344
LncRNA H19 Upregulation Participates in the Response of Glioma Cells to Radiation.
Kuang Y, Bing Z, Jin X, Li Q
BioMed research international 2021;2021:1728352
BioMed research international 2021;2021:1728352
CircMETTL3, upregulated in a m6A-dependent manner, promotes breast cancer progression.
Li Z, Yang HY, Dai XY, Zhang X, Huang YZ, Shi L, Wei JF, Ding Q
International journal of biological sciences 2021;17(5):1178-1190
International journal of biological sciences 2021;17(5):1178-1190
Thymoquinone Suppresses the Proliferation, Migration and Invasiveness through Regulating ROS, Autophagic Flux and miR-877-5p in Human Bladder Carcinoma Cells.
Zhou X, Wang F, Wu H, Chen X, Zhang Y, Lin J, Cai Y, Xiang J, He N, Hu Z, Jin X
International journal of biological sciences 2021;17(13):3456-3475
International journal of biological sciences 2021;17(13):3456-3475
LINC00839 Regulates Proliferation, Migration, Invasion, Apoptosis and Glycolysis in Neuroblastoma Cells Through miR-338-3p/GLUT1 Axis.
Yang L, Pei L, Yi J
Neuropsychiatric disease and treatment 2021;17:2027-2040
Neuropsychiatric disease and treatment 2021;17:2027-2040
Rufinamide (RUF) suppresses inflammation and maintains the integrity of the blood-brain barrier during kainic acid-induced brain damage.
Yu H, He B, Han X, Yan T
Open life sciences 2021;16(1):845-855
Open life sciences 2021;16(1):845-855
p53 Promoted Ferroptosis in Ovarian Cancer Cells Treated with Human Serum Incubated-Superparamagnetic Iron Oxides.
Zhang Y, Xia M, Zhou Z, Hu X, Wang J, Zhang M, Li Y, Sun L, Chen F, Yu H
International journal of nanomedicine 2021;16:283-296
International journal of nanomedicine 2021;16:283-296
Self-Assembled DNA Nanostructure as a Carrier for Targeted siRNA Delivery in Glioma Cells.
Zhou Y, Yang Q, Wang F, Zhou Z, Xu J, Cheng S, Cheng Y
International journal of nanomedicine 2021;16:1805-1817
International journal of nanomedicine 2021;16:1805-1817
Geniposide from Gardenia jasminoides var. radicans Makino Attenuates Myocardial Injury in Spontaneously Hypertensive Rats via Regulating Apoptotic and Energy Metabolism Signalling Pathway.
Hou Y, Yuan P, Fu Y, Zhang Q, Gao L, Wei Y, Zheng X, Feng W
Drug design, development and therapy 2021;15:949-962
Drug design, development and therapy 2021;15:949-962
The Ghrelin/Growth Hormone Secretagogue Receptor System Is Involved in the Rapid and Sustained Antidepressant-Like Effect of Paeoniflorin.
Zhang Y, Zhu MZ, Qin XH, Zeng YN, Zhu XH
Frontiers in neuroscience 2021;15:631424
Frontiers in neuroscience 2021;15:631424
Gamma Radiation Induce Inflammasome Signaling and Pyroptosis in Microvascular Endothelial Cells.
Smith AO, Ju W, Adzraku SY, Wenyi L, Yuting C, Qiao J, Xu K, Zeng L
Journal of inflammation research 2021;14:3277-3288
Journal of inflammation research 2021;14:3277-3288
Curcumin-Alleviated Osteoarthritic Progression in Rats Fed a High-Fat Diet by Inhibiting Apoptosis and Activating Autophagy via Modulation of MicroRNA-34a.
Yao J, Liu X, Sun Y, Dong X, Liu L, Gu H
Journal of inflammation research 2021;14:2317-2331
Journal of inflammation research 2021;14:2317-2331
LncRNA MALAT1 promotes breast cancer progression by sponging miR101-3p to mediate mTOR/PKM2 signal transmission.
Shao J, Zhang Q, Wang P, Wang Z
American journal of translational research 2021;13(9):10262-10275
American journal of translational research 2021;13(9):10262-10275
STAT5 inhibitor attenuates atherosclerosis via inhibition of inflammation: the role of STAT5 in atherosclerosis.
Wang X, Ding X, Yan J, Lu Z, Cao H, Ni X, Ying Y
American journal of translational research 2021;13(3):1422-1431
American journal of translational research 2021;13(3):1422-1431
Novel lncRNA LINC01614 Facilitates Bladder Cancer Proliferation, Migration and Invasion Through the miR-217/RUNX2/Wnt/β-Catenin Axis.
Wang Z, Yan H, Cheng D, Xu L, Shen T, Chen Y, Han R, Xue Y
Cancer management and research 2021;13:8387-8397
Cancer management and research 2021;13:8387-8397
Calcitriol Alleviates MPP+- and MPTP-Induced Parthanatos Through the VDR/PARP1 Pathway in the Model of Parkinson's Disease.
Hu J, Wu J, Wan F, Kou L, Yin S, Sun Y, Li Y, Zhou Q, Wang T
Frontiers in aging neuroscience 2021;13:657095
Frontiers in aging neuroscience 2021;13:657095
Irisin Contributes to Neuroprotection by Promoting Mitochondrial Biogenesis After Experimental Subarachnoid Hemorrhage.
Tu T, Yin S, Pang J, Zhang X, Zhang L, Zhang Y, Xie Y, Guo K, Chen L, Peng J, Jiang Y
Frontiers in aging neuroscience 2021;13:640215
Frontiers in aging neuroscience 2021;13:640215
Ubenimex Suppresses the Ability of Migration and Invasion in Gastric Cancer Cells by Alleviating the Activity of the CD13/NAB1/MAPK Pathway.
Liu X, Guo Q, Jing F, Zhou C, Xiu T, Shi Y, Jing F
Cancer management and research 2021;13:4483-4495
Cancer management and research 2021;13:4483-4495
ARRB1 Drives Gallbladder Cancer Progression by Facilitating TAK1/MAPK Signaling Activation.
Zhang X, Kong Z, Xu X, Yun X, Chao J, Ding D, Li T, Gao Y, Guan N, Zhu C, Qin X
Journal of Cancer 2021;12(7):1926-1935
Journal of Cancer 2021;12(7):1926-1935
Overexpression of TC2N is associated with poor prognosis in gastric cancer.
Xu J, Ou X, Li J, Cai Q, Sun K, Ye J, Peng J
Journal of Cancer 2021;12(3):807-817
Journal of Cancer 2021;12(3):807-817
Nogo-B receptor is required for stabilizing TGF-β type I receptor and promotes the TGF-β1-induced epithelial-to-mesenchymal transition of non-small cell lung cancer.
Wu D, Zhao B, Song Y, Chi X, Fu H, Guan T, Zhang L, Yang X, Hu K, Huang R, Jin X, Miao QR, Shao S
Journal of Cancer 2021;12(3):717-725
Journal of Cancer 2021;12(3):717-725
Punicalin Attenuates Breast Cancer-Associated Osteolysis by Inhibiting the NF-κB Signaling Pathway of Osteoclasts.
Li T, Jiang G, Hu X, Yang D, Tan T, Gao Z, Chen Z, Xiang C, Li S, Ouyang Z, Guo X
Frontiers in pharmacology 2021;12:789552
Frontiers in pharmacology 2021;12:789552
Comprehensive Analysis of the Tumor Microenvironment and Ferroptosis-Related Genes Predict Prognosis with Ovarian Cancer.
Li XX, Xiong L, Wen Y, Zhang ZJ
Frontiers in genetics 2021;12:774400
Frontiers in genetics 2021;12:774400
Transcriptomic Profiling Reveals the Antiapoptosis and Antioxidant Stress Effects of Fos in Ischemic Stroke.
Mu Q, Zhang Y, Gu L, Gerner ST, Qiu X, Tao Q, Pang J, Dipritu G, Zhang L, Yin S, Jiang Y, Peng J
Frontiers in neurology 2021;12:728984
Frontiers in neurology 2021;12:728984
Brd4 Regulates the Homeostasis of CD8+ T-Lymphocytes and Their Proliferation in Response to Antigen Stimulation.
Peng Z, Zhang Y, Ma X, Zhou M, Wu S, Song Z, Yuan Y, Chen Y, Li Y, Wang G, Huang F, Qiao Y, Xia B, Liu W, Liu J, Zhang X, He X, Pan T, Xu H, Zhang H
Frontiers in immunology 2021;12:728082
Frontiers in immunology 2021;12:728082
Targeting Wnt Signaling in the Tumor Immune Microenvironment to Enhancing EpCAM CAR T-Cell therapy.
Li W, Zhou Y, Wu Z, Shi Y, Tian E, Zhu Y, Wang T, Dou W, Meng X, Chen M, Zhai B, Zhu D
Frontiers in pharmacology 2021;12:724306
Frontiers in pharmacology 2021;12:724306
Internal Disulfide Bonding and Glycosylation of Interleukin-7 Protect Against Proteolytic Inactivation by Neutrophil Metalloproteinases and Serine Proteases.
Vandooren J, Pereira RVS, Ugarte-Berzal E, Rybakin V, Noppen S, Stas MR, Bernaerts E, Ganseman E, Metzemaekers M, Schols D, Proost P, Opdenakker G
Frontiers in immunology 2021;12:701739
Frontiers in immunology 2021;12:701739
DHAV-1 Blocks the Signaling Pathway Upstream of Type I Interferon by Inhibiting the Interferon Regulatory Factor 7 Protein.
Lai Y, Xia X, Cheng A, Wang M, Ou X, Mao S, Sun D, Zhang S, Yang Q, Wu Y, Zhu D, Jia R, Chen S, Liu M, Zhao XX, Huang J, Gao Q, Tian B, Liu Y, Yu Y, Zhang L, Pan L
Frontiers in microbiology 2021;12:700434
Frontiers in microbiology 2021;12:700434
Chlorogenic Acid Improves NAFLD by Regulating gut Microbiota and GLP-1.
Shi A, Li T, Zheng Y, Song Y, Wang H, Wang N, Dong L, Shi H
Frontiers in pharmacology 2021;12:693048
Frontiers in pharmacology 2021;12:693048
Sinapic Acid Reduces Oxidative Stress and Pyroptosis via Inhibition of BRD4 in Alcoholic Liver Disease.
Chu J, Yan R, Wang S, Li G, Kang X, Hu Y, Lin M, Shan W, Zhao Y, Wang Z, Sun R, Yao J, Zhang N
Frontiers in pharmacology 2021;12:668708
Frontiers in pharmacology 2021;12:668708
The Protective Effects of Sulforaphane on High-Fat Diet-Induced Obesity in Mice Through Browning of White Fat.
Liu Y, Fu X, Chen Z, Luo T, Zhu C, Ji Y, Bian Z
Frontiers in pharmacology 2021;12:665894
Frontiers in pharmacology 2021;12:665894
Yi-Qi-Jian-Pi Formula Suppresses RIPK1/RIPK3-Complex-Dependent Necroptosis of Hepatocytes Through ROS Signaling and Attenuates Liver Injury in Vivo and in Vitro.
Wang F, Tang L, Liang B, Jin C, Gao L, Li Y, Li Z, Shao J, Zhang Z, Tan S, Zhang F, Zheng S
Frontiers in pharmacology 2021;12:658811
Frontiers in pharmacology 2021;12:658811
Neuroprotective Effects of Oxymatrine on PI3K/Akt/mTOR Pathway After Hypoxic-Ischemic Brain Damage in Neonatal Rats.
Wei W, Lu M, Lan XB, Liu N, Su WK, Dushkin AV, Yu JQ
Frontiers in pharmacology 2021;12:642415
Frontiers in pharmacology 2021;12:642415
Chronic Intermittent Hypobaric Hypoxia Decreases High Blood Pressure by Stabilizing the Vascular Renin-Angiotensin System in Spontaneously Hypertensive Rats.
Chen H, Yu B, Guo X, Hua H, Cui F, Guan Y, Tian Y, Zhang X, Zhang Y, Ma H
Frontiers in physiology 2021;12:639454
Frontiers in physiology 2021;12:639454
Isovitexin Inhibits Ginkgolic Acids-Induced Inflammation Through Downregulating SHP2 Activation.
Zhang Y, Qi Z, Wang W, Wang L, Cao F, Zhao L, Fang X
Frontiers in pharmacology 2021;12:630320
Frontiers in pharmacology 2021;12:630320
SNAPIN Regulates Cell Cycle Progression to Promote Pancreatic β Cell Growth.
Jiang M, Kuang Z, He Y, Cao Y, Yu T, Cheng J, Liu W, Wang W
Frontiers in endocrinology 2021;12:624309
Frontiers in endocrinology 2021;12:624309
FLI1 Induces Megakaryopoiesis Gene Expression Through WAS/WIP-Dependent and Independent Mechanisms; Implications for Wiskott-Aldrich Syndrome.
Wang C, Sample KM, Gajendran B, Kapranov P, Liu W, Hu A, Zacksenhaus E, Li Y, Hao X, Ben-David Y
Frontiers in immunology 2021;12:607836
Frontiers in immunology 2021;12:607836
Histone demethylase JMJD3 protects against renal fibrosis by suppressing TGFβ and Notch signaling and preserving PTEN expression.
Yu C, Xiong C, Tang J, Hou X, Liu N, Bayliss G, Zhuang S
Theranostics 2021;11(6):2706-2721
Theranostics 2021;11(6):2706-2721
KDM6A promotes imatinib resistance through YY1-mediated transcriptional upregulation of TRKA independently of its demethylase activity in chronic myelogenous leukemia.
Zhang C, Shen L, Zhu Y, Xu R, Deng Z, Liu X, Ding Y, Wang C, Shi Y, Bei L, Wei D, Thorne RF, Zhang XD, Yu L, Chen S
Theranostics 2021;11(6):2691-2705
Theranostics 2021;11(6):2691-2705
Suppressing Sart1 to modulate macrophage polarization by siRNA-loaded liposomes: a promising therapeutic strategy for pulmonary fibrosis.
Pan T, Zhou Q, Miao K, Zhang L, Wu G, Yu J, Xu Y, Xiong W, Li Y, Wang Y
Theranostics 2021;11(3):1192-1206
Theranostics 2021;11(3):1192-1206
ACSS3 represses prostate cancer progression through downregulating lipid droplet-associated protein PLIN3.
Zhou L, Song Z, Hu J, Liu L, Hou Y, Zhang X, Yang X, Chen K
Theranostics 2021;11(2):841-860
Theranostics 2021;11(2):841-860
Growth hormone receptor disrupts glucose homeostasis via promoting and stabilizing retinol binding protein 4.
Liu J, Nie C, Xue L, Yan Y, Liu S, Sun J, Fan M, Qian H, Ying H, Wang L, Li Y
Theranostics 2021;11(17):8283-8300
Theranostics 2021;11(17):8283-8300
Bioengineering CXCR4-overexpressing cell membrane functionalized ROS-responsive nanotherapeutics for targeting cerebral ischemia-reperfusion injury.
Luo L, Zang G, Liu B, Qin X, Zhang Y, Chen Y, Zhang H, Wu W, Wang G
Theranostics 2021;11(16):8043-8056
Theranostics 2021;11(16):8043-8056
Deciphering the autophagy regulatory network via single-cell transcriptome analysis reveals a requirement for autophagy homeostasis in spermatogenesis.
Wang M, Xu Y, Zhang Y, Chen Y, Chang G, An G, Yang X, Zheng C, Zhao J, Liu Z, Wang D, Miao K, Rao S, Dai M, Wang D, Zhao XY
Theranostics 2021;11(10):5010-5027
Theranostics 2021;11(10):5010-5027
Epigenetically silenced linc00261 contributes to the metastasis of hepatocellular carcinoma via inducing the deficiency of FOXA2 transcription.
Chen Z, Xiang L, Hu Z, Ou H, Liu X, Yu L, Chen W, Jiang L, Yu Q, Fang Y, Xu Y, Liu Q, Huang Y, Li X, Yang D
American journal of cancer research 2021;11(1):277-296
American journal of cancer research 2021;11(1):277-296
Glia Maturation Factor Beta as a Novel Biomarker and Therapeutic Target for Hepatocellular Carcinoma.
Sun W, Hu C, Wang T, Wang J, Zhang J, Gao F, Ou Q, Tian H, Jin C, Xu J, Zhang J, Xu GT, Lu L
Frontiers in oncology 2021;11:744331
Frontiers in oncology 2021;11:744331
circRPS16 Promotes Proliferation and Invasion of Hepatocellular Carcinoma by Sponging miR-876-5p to Upregulate SPINK1.
Lin S, Lin Y, Wu Z, Xia W, Miao C, Peng T, Zhao Z, Ji C, Mo Z, Liu X, Jian Z
Frontiers in oncology 2021;11:724415
Frontiers in oncology 2021;11:724415
Calcium Channel Protein ORAI1 Mediates TGF-β Induced Epithelial-to-Mesenchymal Transition in Colorectal Cancer Cells.
Kang Q, Peng X, Li X, Hu D, Wen G, Wei Z, Yuan B
Frontiers in oncology 2021;11:649476
Frontiers in oncology 2021;11:649476
Yap1-2 Isoform Is the Primary Mediator in TGF-β1 Induced EMT in Pancreatic Cancer.
Gao C, Quan MY, Chen QJ, Yang R, Wu Y, Liu JY, Lin ZY, Li X, Cai JT, Jiang TF, Xu L, Mossahebi-Mohammadi M, Guo Q, Zhang JS
Frontiers in oncology 2021;11:649290
Frontiers in oncology 2021;11:649290
Subunit Vaccine ESAT-6:c-di-AMP Delivered by Intranasal Route Elicits Immune Responses and Protects Against Mycobacterium tuberculosis Infection.
Ning H, Zhang W, Kang J, Ding T, Liang X, Lu Y, Guo C, Sun W, Wang H, Bai Y, Shen L
Frontiers in cellular and infection microbiology 2021;11:647220
Frontiers in cellular and infection microbiology 2021;11:647220
The Anti-Inflammatory Effect and Mucosal Barrier Protection of Clostridium butyricum RH2 in Ceftriaxone-Induced Intestinal Dysbacteriosis.
Li Y, Liu M, Liu H, Sui X, Liu Y, Wei X, Liu C, Cheng Y, Ye W, Gao B, Wang X, Lu Q, Cheng H, Zhang L, Yuan J, Li M
Frontiers in cellular and infection microbiology 2021;11:647048
Frontiers in cellular and infection microbiology 2021;11:647048
PTIP Inhibits Cell Invasion in Esophageal Squamous Cell Carcinoma via Modulation of EphA2 Expression.
Han X, Zhu Y, Shen L, Zhou Y, Pang L, Zhou W, Gu H, Han K, Yang Y, Jiang C, Xie J, Zhang C, Ding L
Frontiers in oncology 2021;11:629916
Frontiers in oncology 2021;11:629916
Toxicity evaluation of mesoporous silica particles Santa Barbara No. 15 amorphous in human umbilical vein endothelial cells: influence of particle morphology.
Teng W, Yang Z, Wang S, Xiong D, Chen Y, Wu Z
Journal of applied toxicology : JAT 2021 Sep;41(9):1467-1478
Journal of applied toxicology : JAT 2021 Sep;41(9):1467-1478
Remarkable inhibition effects of afatinib alone or combining with paclitaxel in esophageal squamous cell carcinoma.
Yang LY, Cheng ZJ, Liu Z, Wang D, Zhang N, Fan ZL, Cai HQ, Zhang Y, Cai Y, Xu X, Wang JH, Du GH, Hao JJ, Wang MR
Journal of gastroenterology and hepatology 2021 Sep;36(9):2513-2522
Journal of gastroenterology and hepatology 2021 Sep;36(9):2513-2522
Endogenous reverse transcriptase and RNase H-mediated antiviral mechanism in embryonic stem cells.
Wu J, Wu C, Xing F, Cao L, Zeng W, Guo L, Li P, Zhong Y, Jiang H, Luo M, Shi G, Bu L, Ji Y, Hou P, Peng H, Huang J, Li C, Guo D
Cell research 2021 Sep;31(9):998-1010
Cell research 2021 Sep;31(9):998-1010
TBC1 domain family member 23 interacts with Ras-related protein Rab-11A to promote poor prognosis of non-small-cell lung cancer via β1-integrin.
Zhang Y, Su H, Wudu M, Ren H, Xu Y, Zhang Q, Jiang J, Wang Q, Jiang X, Zhang B, Liu Z, Zou Z, Qiu X
Journal of cellular and molecular medicine 2021 Sep;25(18):8821-8835
Journal of cellular and molecular medicine 2021 Sep;25(18):8821-8835
Salusin‑β participates in high glucose‑induced HK‑2 cell ferroptosis in a Nrf‑2‑dependent manner.
Wang WJ, Jiang X, Gao CC, Chen ZW
Molecular medicine reports 2021 Sep;24(3)
Molecular medicine reports 2021 Sep;24(3)
Mitochondrial calcium uniporter promotes cell proliferation and migration in esophageal cancer.
Miao Y, Wang X, Lai Y, Lin W, Huang Y, Yin H, Hou R, Zhang F
Oncology letters 2021 Sep;22(3):686
Oncology letters 2021 Sep;22(3):686
Protein arginine methyltransferase 5 mediates THP-1-derived macrophage activation dependent on NF-κB in endometriosis.
Chai X, Wu X, He L, Ding H
Experimental and therapeutic medicine 2021 Sep;22(3):1003
Experimental and therapeutic medicine 2021 Sep;22(3):1003
Treadmill exercise alleviates neuronal damage by suppressing NLRP3 inflammasome and microglial activation in the MPTP mouse model of Parkinson's disease.
Wang W, Lv Z, Gao J, Liu M, Wang Y, Tang C, Xiang J
Brain research bulletin 2021 Sep;174:349-358
Brain research bulletin 2021 Sep;174:349-358
Magnesium-L-threonate alleviate colonic inflammation and memory impairment in chronic-plus-binge alcohol feeding mice.
Liu C, Cheng Y, Guo Y, Qian H
Brain research bulletin 2021 Sep;174:184-193
Brain research bulletin 2021 Sep;174:184-193
Probiotic fermentation of Ganoderma lucidum fruiting body extracts promoted its immunostimulatory activity in mice with dexamethasone-induced immunosuppression.
Li Y, Liu H, Qi H, Tang W, Zhang C, Liu Z, Liu Y, Wei X, Kong Z, Jia S, Du B, Yuan J, Wang C, Li M
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Sep;141:111909
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Sep;141:111909
Blockade of GITRL/GITR signaling pathway attenuates house dust mite-induced allergic asthma in mice through inhibition of MAPKs and NF-κB signaling.
Wang Y, Liu B, Niu C, Zou W, Yang L, Wang T, Tian D, Luo Z, Dai J, Li Q, Liu E, Gong C, Fu Z, Ding F
Molecular immunology 2021 Sep;137:238-246
Molecular immunology 2021 Sep;137:238-246
A methylation-driven gene panel predicts survival in patients with colon cancer.
Peng Y, Zhao J, Yin F, Sharen G, Wu Q, Chen Q, Sun X, Yang J, Wang H, Zhang D
FEBS open bio 2021 Sep;11(9):2490-2506
FEBS open bio 2021 Sep;11(9):2490-2506
Aloe-emodin prevents nerve injury and neuroinflammation caused by ischemic stroke via the PI3K/AKT/mTOR and NF-κB pathway.
Xian M, Cai J, Zheng K, Liu Q, Liu Y, Lin H, Liang S, Wang S
Food & function 2021 Sep 7;12(17):8056-8067
Food & function 2021 Sep 7;12(17):8056-8067
Microglia-derived IL-1β promoted neuronal apoptosis through ER stress-mediated signaling pathway PERK/eIF2α/ATF4/CHOP upon arsenic exposure.
Liu X, Chen Y, Wang H, Wei Y, Yuan Y, Zhou Q, Fang F, Shi S, Jiang X, Dong Y, Li X
Journal of hazardous materials 2021 Sep 5;417:125997
Journal of hazardous materials 2021 Sep 5;417:125997
Microglia jointly degrade fibrillar alpha-synuclein cargo by distribution through tunneling nanotubes.
Scheiblich H, Dansokho C, Mercan D, Schmidt SV, Bousset L, Wischhof L, Eikens F, Odainic A, Spitzer J, Griep A, Schwartz S, Bano D, Latz E, Melki R, Heneka MT
Cell 2021 Sep 30;184(20):5089-5106.e21
Cell 2021 Sep 30;184(20):5089-5106.e21
LncRNA ZNFTR functions as an inhibitor in pancreatic cancer by modulating ATF3/ZNF24/VEGFA pathway.
Li W, Han S, Hu P, Chen D, Zeng Z, Hu Y, Xu F, Tang J, Wang F, Zhao Y, Huang M, Zhao G
Cell death & disease 2021 Sep 3;12(9):830
Cell death & disease 2021 Sep 3;12(9):830
3'HS1 CTCF binding site in human β-globin locus regulates fetal hemoglobin expression.
Himadewi P, Wang XQD, Feng F, Gore H, Liu Y, Yu L, Kurita R, Nakamura Y, Pfeifer GP, Liu J, Zhang X
eLife 2021 Sep 29;10
eLife 2021 Sep 29;10
Identification of HMGCR as the anticancer target of physapubenolide against melanoma cells by in silico target prediction.
Wang HY, Yu P, Chen XS, Wei H, Cao SJ, Zhang M, Zhang Y, Tao YG, Cao DS, Qiu F, Cheng Y
Acta pharmacologica Sinica 2021 Sep 29;
Acta pharmacologica Sinica 2021 Sep 29;
Sodium Tanshinone IIA Sulfonate Attenuates Cigarette Smoke Extract-Induced Mitochondrial Dysfunction, Oxidative Stress, and Apoptosis in Alveolar Epithelial Cells by Enhancing SIRT1 Pathway.
Guan R, Yao H, Li Z, Qian J, Yuan L, Cai Z, Ding M, Liu W, Xu J, Li Y, Sun D, Wang J, Lu W
Toxicological sciences : an official journal of the Society of Toxicology 2021 Sep 28;183(2):352-362
Toxicological sciences : an official journal of the Society of Toxicology 2021 Sep 28;183(2):352-362
Nano chitosan-zinc complex improves the growth performance and antioxidant capacity of the small intestine in weaned piglets.
Zhang M, Hou G, Hu P, Feng D, Wang J, Zhu W
The British journal of nutrition 2021 Sep 28;126(6):801-812
The British journal of nutrition 2021 Sep 28;126(6):801-812
Different concentrations of C5a affect human dental pulp mesenchymal stem cells differentiation.
Liu J, Wei X, Hu J, Tan X, Kang X, Gao L, Li N, Shi X, Yuan M, Hu W, Liu M
BMC oral health 2021 Sep 24;21(1):470
BMC oral health 2021 Sep 24;21(1):470
Proteomics identifies a novel role of fibrinogen-like protein 1 in Crohn's disease.
Sun XL, Qiao LC, Gong J, Wen K, Xu ZZ, Yang BL
World journal of gastroenterology 2021 Sep 21;27(35):5946-5957
World journal of gastroenterology 2021 Sep 21;27(35):5946-5957
Mechanistic study of lncRNA UCA1 promoting growth and cisplatin resistance in lung adenocarcinoma.
Fu J, Pan J, Yang X, Zhang Y, Shao F, Chen J, Huang K, Wang Y
Cancer cell international 2021 Sep 20;21(1):505
Cancer cell international 2021 Sep 20;21(1):505
Structural Studies of Water-Insoluble β-Glucan from Oat Bran and Its Effect on Improving Lipid Metabolism in Mice Fed High-Fat Diet.
Yu S, Wang J, Li Y, Wang X, Ren F, Wang X
Nutrients 2021 Sep 18;13(9)
Nutrients 2021 Sep 18;13(9)
Aged Ripe Pu-erh Tea Reduced Oxidative Stress-Mediated Inflammation in Dextran Sulfate Sodium-Induced Colitis Mice by Regulating Intestinal Microbes.
Hu S, Li S, Liu Y, Sun K, Luo L, Zeng L
Journal of agricultural and food chemistry 2021 Sep 15;69(36):10592-10605
Journal of agricultural and food chemistry 2021 Sep 15;69(36):10592-10605
Reduced DAPK1 Expression Promotes Stem Cell-Like Characteristics of Prostate Cancer Cells by Activating ZEB1 via Hippo/YAP Signaling Pathway.
Nong S, Wei Z, Wang Z, Ma L, Guan Y, Ni J
Stem cells and development 2021 Sep 15;30(18):934-945
Stem cells and development 2021 Sep 15;30(18):934-945
Raf1 interacts with OIP5 to participate in oxaliplatin-induced neuropathic pain.
Yu W, Zheng Z, Wei W, Li L, Zhang Y, Sun Y, Cao J, Zang W, Shao J
Life sciences 2021 Sep 15;281:119804
Life sciences 2021 Sep 15;281:119804
Abnormal spatiotemporal expression pattern of progranulin and neurodevelopment impairment in VPA-induced ASD rat model.
Lan J, Hu Y, Wang X, Zheng W, Liao A, Wang S, Li Y, Wang Y, Yang F, Chen D
Neuropharmacology 2021 Sep 15;196:108689
Neuropharmacology 2021 Sep 15;196:108689
Effect of different exercise training intensities on age-related cardiac damage in male mice.
Pei Z, Yang C, Guo Y, Dong M, Wang F
Aging 2021 Sep 14;13(17):21700-21711
Aging 2021 Sep 14;13(17):21700-21711
Nintedanib Regulates GRK2 and CXCR2 to Reduce Neutrophil Recruitment in Endotoxin-Induced Lung Injury.
Su VY, Chen WC, Yu WK, Wu HH, Chen H, Yang KY
International journal of molecular sciences 2021 Sep 13;22(18)
International journal of molecular sciences 2021 Sep 13;22(18)
Betulinic acid induces autophagy-dependent apoptosis via Bmi-1/ROS/AMPK-mTOR-ULK1 axis in human bladder cancer cells.
Zhang Y, He N, Zhou X, Wang F, Cai H, Huang SH, Chen X, Hu Z, Jin X
Aging 2021 Sep 12;13(17):21251-21267
Aging 2021 Sep 12;13(17):21251-21267
MicroRNA-30c-5p protects against myocardial ischemia/reperfusion injury via regulation of Bach1/Nrf2.
Sun M, Guo M, Ma G, Zhang N, Pan F, Fan X, Wang R
Toxicology and applied pharmacology 2021 Sep 1;426:115637
Toxicology and applied pharmacology 2021 Sep 1;426:115637
Analysis of the microRNA and mRNA expression profile of ricin toxin-treated RAW264.7 cells reveals that miR-155-3p suppresses cell inflammation by targeting GAB2.
Liu Z, Zhang X, Dong M, Liu Z, Wang Y, Yu H, Yu K, Xu N, Liu W, Song H
Toxicology letters 2021 Sep 1;347:67-77
Toxicology letters 2021 Sep 1;347:67-77
Resveratrol-mediated neurorestoration after cerebral ischemic injury - Sonic Hedgehog signaling pathway.
Yu P, Wang L, Tang F, Guo S, Liao H, Fan C, Yang Q
Life sciences 2021 Sep 1;280:119715
Life sciences 2021 Sep 1;280:119715
Phenotypic differences in the inner ears of CBA/CaJ and C57BL/6J mice carrying missense and single base pair deletion mutations in the Cdh23 gene.
Zhao T, Ma P, Zhao F, Zheng T, Yan B, Zhang Q, Yuan J, Hu B, Yang Y, Hu J, Geng R, Hu BH, Sun T, Zheng QY, Li B
Journal of neuroscience research 2021 Oct;99(10):2743-2758
Journal of neuroscience research 2021 Oct;99(10):2743-2758
Activation of CB2 receptor inhibits pyroptosis and subsequently ameliorates cecal ligation and puncture-induced sepsis.
Zhang B, Zheng F, Liu A, Li Z, Zheng F, Liu Q, Yang L, Chen K, Wang Y, Zhang Z, He Q, Zhan J
International immunopharmacology 2021 Oct;99:108038
International immunopharmacology 2021 Oct;99:108038
Inhibition of TNFAIP1 ameliorates the oxidative stress and inflammatory injury in myocardial ischemia/reperfusion injury through modulation of Akt/GSK-3β/Nrf2 pathway.
Wen L, Yang QH, Ma XL, Li T, Xiao S, Sun CF
International immunopharmacology 2021 Oct;99:107993
International immunopharmacology 2021 Oct;99:107993
Inhibition of ER stress attenuates kidney injury and apoptosis induced by 3-MCPD via regulating mitochondrial fission/fusion and Ca2+ homeostasis.
Zhong Y, Jin C, Han J, Zhu J, Liu Q, Sun D, Xia X, Peng X
Cell biology and toxicology 2021 Oct;37(5):795-809
Cell biology and toxicology 2021 Oct;37(5):795-809
The long non-coding RNA PFI protects against pulmonary fibrosis by interacting with splicing regulator SRSF1.
Sun J, Jin T, Su W, Guo Y, Niu Z, Guo J, Li L, Wang J, Ma L, Yu T, Li X, Zhou Y, Shan H, Liang H
Cell death and differentiation 2021 Oct;28(10):2916-2930
Cell death and differentiation 2021 Oct;28(10):2916-2930
Exosomes derived from idiopathic gingival fibroma fibroblasts regulate gingival fibroblast proliferation and apoptosis.
Yin S, Jia F, Ran L, Xie L, Wu Z, Zhan Y, Zhang Y, Zhang M
Oral diseases 2021 Oct;27(7):1789-1795
Oral diseases 2021 Oct;27(7):1789-1795
Sepsis induces muscle atrophy by inhibiting proliferation and promoting apoptosis via PLK1-AKT signalling.
Cao YY, Wang Z, Yu T, Zhang Y, Wang ZH, Lu ZM, Lu WH, Yu JB
Journal of cellular and molecular medicine 2021 Oct;25(20):9724-9739
Journal of cellular and molecular medicine 2021 Oct;25(20):9724-9739
Human umbilical cord mesenchymal stem cells ameliorate depression by regulating Jmjd3 and microglia polarization in myocardial infarction mice.
Zhang Y, Wang X, Li Y, Liu R, Pan J, Tang X, Sun S, Liu J, Ma W
Psychopharmacology 2021 Oct;238(10):2973-2984
Psychopharmacology 2021 Oct;238(10):2973-2984
Dihydroartemisinin suppresses proliferation, migration, the Wnt/β-catenin pathway and EMT via TNKS in gastric cancer.
Ma Y, Zhang P, Zhang Q, Wang X, Miao Q, Lyu X, Cui B, Ma H
Oncology letters 2021 Oct;22(4):688
Oncology letters 2021 Oct;22(4):688
The role of alcohol dehydrogenase 1C in regulating inflammatory responses in ulcerative colitis.
Song F, Zhang Y, Pan Z, Hu X, Zhang Q, Huang F, Ye X, Huang P
Biochemical pharmacology 2021 Oct;192:114691
Biochemical pharmacology 2021 Oct;192:114691
Integrating systematic pharmacology-based strategy and experimental validation to explore the synergistic pharmacological mechanisms of Guanxin V in treating ventricular remodeling.
Liang B, Liang Y, Li R, Zhang H, Gu N
Bioorganic chemistry 2021 Oct;115:105187
Bioorganic chemistry 2021 Oct;115:105187
Myosin 1f-mediated activation of microglia contributes to the photoreceptor degeneration in a mouse model of retinal detachment.
Wang Y, Zhao X, Gao M, Wan X, Guo Y, Qu Y, Chen Y, Li T, Liu H, Jiang M, Wang F, Sun X
Cell death & disease 2021 Oct 9;12(10):926
Cell death & disease 2021 Oct 9;12(10):926
Ferrostatin-1 alleviated TNBS induced colitis via the inhibition of ferroptosis.
Xu J, Liu S, Cui Z, Wang X, Ning T, Wang T, Zhang N, Xie S, Min L, Zhang S, Liang C, Zhu S
Biochemical and biophysical research communications 2021 Oct 8;573:48-54
Biochemical and biophysical research communications 2021 Oct 8;573:48-54
EphA2 inhibits SRA01/04 cells apoptosis by suppressing autophagy via activating PI3K/Akt/mTOR pathway.
Han J, Wang L, Lv H, Liu J, Dong Y, Shi L, Ji Q
Archives of biochemistry and biophysics 2021 Oct 30;711:109024
Archives of biochemistry and biophysics 2021 Oct 30;711:109024
UM-6 induces autophagy and apoptosis via the Hippo-YAP signaling pathway in cervical cancer.
Wang D, He J, Dong J, Wu S, Liu S, Zhu H, Xu T
Cancer letters 2021 Oct 28;519:2-19
Cancer letters 2021 Oct 28;519:2-19
ZEB1 represses biogenesis of circ-DOCK5 to facilitate metastasis in esophageal squamous cell carcinoma via a positive feedback loop with TGF-β.
Meng L, Zheng Y, Liu S, Ju Y, Ren S, Sang Y, Zhu Y, Gu L, Liu F, Zhao Y, Zhang X, Sang M
Cancer letters 2021 Oct 28;519:117-129
Cancer letters 2021 Oct 28;519:117-129
RCAN1.4 attenuates renal fibrosis through inhibiting calcineurin-mediated nuclear translocation of NFAT2.
Zhang J, Chen H, Weng X, Liu H, Chen Z, Huang Q, Wang L, Liu X
Cell death discovery 2021 Oct 27;7(1):317
Cell death discovery 2021 Oct 27;7(1):317
Subtractive CRISPR screen identifies the ATG16L1/vacuolar ATPase axis as required for non-canonical LC3 lipidation.
Ulferts R, Marcassa E, Timimi L, Lee LC, Daley A, Montaner B, Turner SD, Florey O, Baillie JK, Beale R
Cell reports 2021 Oct 26;37(4):109899
Cell reports 2021 Oct 26;37(4):109899
STING-mediated inflammation contributes to Gao binge ethanol feeding model.
Wang L, You HM, Meng HW, Pan XY, Chen X, Bi YH, Zhang YF, Li JJ, Yin NN, Zhang ZW, Huang C, Li J
Journal of cellular physiology 2021 Oct 26;
Journal of cellular physiology 2021 Oct 26;
Hypoxic tubular epithelial cells regulate the angiogenesis of HMEC-1 cells via mediation of Rab7/MMP-2 axis.
Yang Y, Wang J, Zhang Y, Hu X, Li L, Chen P
Aging 2021 Oct 25;13(20):23769-23779
Aging 2021 Oct 25;13(20):23769-23779
Berberine Inhibits MDA-MB-231 Cells as an Agonist of G Protein-Coupled Estrogen Receptor 1.
Qi M, Liu X, Zhou Y, Wang H, Zhao Y, Ren J, Xiang J
International journal of molecular sciences 2021 Oct 24;22(21)
International journal of molecular sciences 2021 Oct 24;22(21)
Fructooligosaccharide supplementation alleviated the pathological immune response and prevented the impairment of intestinal barrier in DSS-induced acute colitis mice.
Liao M, Zhang Y, Qiu Y, Wu Z, Zhong Z, Zeng X, Zeng Y, Xiong L, Wen Y, Liu R
Food & function 2021 Oct 19;12(20):9844-9854
Food & function 2021 Oct 19;12(20):9844-9854
Gut microbiota-dependent catabolites of tryptophan play a predominant role in the protective effects of turmeric polysaccharides against DSS-induced ulcerative colitis.
Yang C, Du Y, Ren D, Yang X, Zhao Y
Food & function 2021 Oct 19;12(20):9793-9807
Food & function 2021 Oct 19;12(20):9793-9807
SMAD2 regulates testicular development and testosterone synthesis in Hu sheep.
Yang H, Wan Z, Jin Y, Wang F, Zhang Y
Theriogenology 2021 Oct 15;174:139-148
Theriogenology 2021 Oct 15;174:139-148
METTL3 improves cardiomyocyte proliferation upon myocardial infarction via upregulating miR-17-3p in a DGCR8-dependent manner.
Zhao K, Yang C, Zhang J, Sun W, Zhou B, Kong X, Shi J
Cell death discovery 2021 Oct 13;7(1):291
Cell death discovery 2021 Oct 13;7(1):291
Chorionic villus-derived mesenchymal stem cell-mediated autophagy promotes the proliferation and invasiveness of trophoblasts under hypoxia by activating the JAK2/STAT3 signalling pathway.
Chu Y, Zhu C, Yue C, Peng W, Chen W, He G, Liu C, Lv Y, Gao G, Yao K, Han R, Hu X, Zhang Y, Ye Y
Cell & bioscience 2021 Oct 13;11(1):182
Cell & bioscience 2021 Oct 13;11(1):182
Methamphetamine mediates apoptosis of vascular smooth muscle cells via the chop-related endoplasmic reticulum stress pathway.
Tan X, Cai D, Chen N, Du S, Qiao D, Yue X, Wang T, Li J, Xie W, Wang H
Toxicology letters 2021 Oct 10;350:98-110
Toxicology letters 2021 Oct 10;350:98-110
Exercise Intervention Mitigates Pathological Liver Changes in NAFLD Zebrafish by Activating SIRT1/AMPK/NRF2 Signaling.
Zou Y, Chen Z, Sun C, Yang D, Zhou Z, Peng X, Zheng L, Tang C
International journal of molecular sciences 2021 Oct 10;22(20)
International journal of molecular sciences 2021 Oct 10;22(20)
Effects of cannabinoid (CBD) on blood brain barrier permeability after brain injury in rats.
Jiang H, Li H, Cao Y, Zhang R, Zhou L, Zhou Y, Zeng X, Wu J, Wu D, Wu D, Guo X, Li X, Wu H, Li P
Brain research 2021 Oct 1;1768:147586
Brain research 2021 Oct 1;1768:147586
Melatonin alleviated oxidative stress induced by energy restriction on sheep Leydig cells through Sirt1/Sod2 pathway.
Ma J, Yang H, Liu L, Wan Y, Wang F
Theriogenology 2021 Oct 1;173:83-92
Theriogenology 2021 Oct 1;173:83-92
Vitamin A and retinoic acid accelerate the attenuation of intestinal adaptability upon feeding induced by high-fat diet in mice.
Hong W, Xu D, Song X, Niu B, Zhuang Z, Lu Y, Lei X, Ma R, Lu C, Sun N, Mao Y, Li X
The Journal of nutritional biochemistry 2021 Nov;97:108803
The Journal of nutritional biochemistry 2021 Nov;97:108803
Downregulated fat mass and obesity-associated protein inhibits bone resorption and osteoclastogenesis by nuclear factor-kappa B inactivation.
Zhuang J, Ning H, Wang M, Zhao W, Jing Y, Liu X, Zu J, Kong P, Wang X, Sun C, Yan J
Cellular signalling 2021 Nov;87:110137
Cellular signalling 2021 Nov;87:110137
Ginsenoside Rg1 attenuates mechanical stress-induced cardiac injury via calcium sensing receptor-related pathway.
Lu ML, Wang J, Sun Y, Li C, Sun TR, Hou XW, Wang HX
Journal of ginseng research 2021 Nov;45(6):683-694
Journal of ginseng research 2021 Nov;45(6):683-694
Nicotinamide improves NAD+ levels to protect against acetaminophen-induced acute liver injury in mice.
Xu J, Zhang L, Jiang R, Hu K, Hu D, Liao C, Jiang S, Yang Y, Huang J, Tang L, Li L
Human & experimental toxicology 2021 Nov;40(11):1938-1946
Human & experimental toxicology 2021 Nov;40(11):1938-1946
Loss of PHLDA1 has a protective role in OGD/R-injured neurons via regulation of the GSK-3β/Nrf2 pathway.
Yang F, Chen R
Human & experimental toxicology 2021 Nov;40(11):1909-1920
Human & experimental toxicology 2021 Nov;40(11):1909-1920
PHLDA3 inhibition protects against myocardial ischemia/reperfusion injury by alleviating oxidative stress and inflammatory response via the Akt/Nrf2 axis.
Meng X, Zhang L, Han B, Zhang Z
Environmental toxicology 2021 Nov;36(11):2266-2277
Environmental toxicology 2021 Nov;36(11):2266-2277
Ferroptosis is involved in the anti-tumor effect of lycorine in renal cell carcinoma cells.
Du Y, Zhao HC, Zhu HC, Jin Y, Wang L
Oncology letters 2021 Nov;22(5):781
Oncology letters 2021 Nov;22(5):781
Maiwei Yangfei decoction prevents bleomycin-induced pulmonary fibrosis in mice.
Xu Y, Peng W, Han D, Feng F, Wang Z, Gu C, Zhou X, Wu Q
Experimental and therapeutic medicine 2021 Nov;22(5):1306
Experimental and therapeutic medicine 2021 Nov;22(5):1306
Th17/IL-17 induces endothelial cell senescence via activation of NF-κB/p53/Rb signaling pathway.
Zhang L, Liu M, Liu W, Hu C, Li H, Deng J, Cao Q, Wang Y, Hu W, Li Q
Laboratory investigation; a journal of technical methods and pathology 2021 Nov;101(11):1418-1426
Laboratory investigation; a journal of technical methods and pathology 2021 Nov;101(11):1418-1426
Starvation induced autophagy promotes the progression of bladder cancer by LDHA mediated metabolic reprogramming.
Li T, Tong H, Yin H, Luo Y, Zhu J, Qin Z, Yin S, He W
Cancer cell international 2021 Nov 7;21(1):597
Cancer cell international 2021 Nov 7;21(1):597
Dual Hyaluronic Acid and Folic Acid Targeting pH-Sensitive Multifunctional 2DG@DCA@MgO-Nano-Core-Shell-Radiosensitizer for Breast Cancer Therapy.
Askar MA, Thabet NM, El-Sayyad GS, El-Batal AI, Abd Elkodous M, El Shawi OE, Helal H, Abdel-Rafei MK
Cancers 2021 Nov 7;13(21)
Cancers 2021 Nov 7;13(21)
Eurycomanol alleviates hyperuricemia by promoting uric acid excretion and reducing purine synthesis.
Bao R, Chen Q, Li Z, Wang D, Wu Y, Liu M, Zhang Y, Wang T
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Nov 6;:153850
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Nov 6;:153850
Isoliquiritigenin-mediated miR-23a-3p inhibition activates PGC-1α to alleviate alcoholic liver injury.
Wang L, Kong L, Xu S, Wang X, Huang K, Wang S, Wu J, Wang C, Sun H, Liu K, Meng Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Nov 5;:153845
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Nov 5;:153845
CircCRIM1 promotes ovarian cancer progression by working as ceRNAs of CRIM1 and targeting miR-383-5p/ZEB2 axis.
Du Y, Liu X, Zhang S, Chen S, Guan X, Li Q, Chen X, Zhao Y
Reproductive biology and endocrinology : RB&E 2021 Nov 30;19(1):176
Reproductive biology and endocrinology : RB&E 2021 Nov 30;19(1):176
miR-23a/b-3p promotes hepatic lipid accumulation by regulating Srebp-1c and Fas.
Li L, Zhang X, Ren H, Huang X, Shen T, Tang W, Dou L, Li J
Journal of molecular endocrinology 2021 Nov 26;68(1):35-49
Journal of molecular endocrinology 2021 Nov 26;68(1):35-49
Activation of RIPK2-mediated NOD1 signaling promotes proliferation and invasion of ovarian cancer cells via NF-κB pathway.
Zhang W, Wang Y
Histochemistry and cell biology 2021 Nov 26;
Histochemistry and cell biology 2021 Nov 26;
Tβ4 ameliorates oxidative damage and apoptosis through ERK/MAPK and 5-HT1A signaling pathway in Aβ insulted SH-SY5Y cells.
Zhang GH, Pare RB, Chin KL, Qian YH
Life sciences 2021 Nov 25;:120178
Life sciences 2021 Nov 25;:120178
Protection of CAPE-pNO2 Against Chronic Myocardial Ischemia by the TGF-Β1/Galectin-3 Pathway In Vivo and In Vitro.
Wan Q, Zhang L, Zhou Q, Han Y, Li Z, Li B
Inflammation 2021 Nov 24;
Inflammation 2021 Nov 24;
Molecular imaging and treatment of PSMA-positive prostate cancer with 99mTc radiolabeled aptamer-siRNA chimeras.
Jiao Y, Xu P, Luan S, Wang X, Gao Y, Zhao C, Fu P
Nuclear medicine and biology 2021 Nov 20;104-105:28-37
Nuclear medicine and biology 2021 Nov 20;104-105:28-37
A novel regulatory mechanism of geniposide for improving glucose homeostasis mediated by circulating RBP4.
Liu J, Song C, Nie C, Sun Y, Wang Y, Xue L, Fan M, Qian H, Wang L, Li Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Nov 19;95:153862
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Nov 19;95:153862
NLRP3 Inflammasome Activation Enhances ADK Expression to Accelerate Epilepsy in Mice.
Zhang H, Yu S, Xia L, Peng X, Wang S, Yao B
Neurochemical research 2021 Nov 19;
Neurochemical research 2021 Nov 19;
Verapamil ameliorates proximal tubular epithelial cells apoptosis and fibrosis in diabetic kidney.
Song Y, Guo F, Zhao Y, Zhao L, Fan X, Zhang Y, Liu Y, Qin G
European journal of pharmacology 2021 Nov 15;911:174552
European journal of pharmacology 2021 Nov 15;911:174552
Programmed cell death 5 improves skeletal muscle insulin resistance by inhibiting IRS-1 ubiquitination through stabilization of MDM2.
Li B, Ye J, Liu R, Weng L, Cao Y, Jia S, Xu C, Liu Y, Yan S, Zheng M
Life sciences 2021 Nov 15;285:119918
Life sciences 2021 Nov 15;285:119918
TM9SF4 is a novel regulator in lineage commitment of bone marrow mesenchymal stem cells to either osteoblasts or adipocytes.
Yu L, Xie M, Zhang F, Wan C, Yao X
Stem cell research & therapy 2021 Nov 13;12(1):573
Stem cell research & therapy 2021 Nov 13;12(1):573
AP39 ameliorates high fat diet-induced liver injury in young rats via alleviation of oxidative stress and mitochondrial impairment.
Yu Y, Ye SM, Liu DY, Yang LQ
Experimental animals 2021 Nov 10;70(4):553-562
Experimental animals 2021 Nov 10;70(4):553-562
Down-regulation of EPB41L4A-AS1 mediated the brain aging and neurodegenerative diseases via damaging synthesis of NAD+ and ATP.
Yang T, Wang Y, Liao W, Zhang S, Wang S, Xu N, Xie W, Luo C, Wang Y, Wang Z, Zhang Y
Cell & bioscience 2021 Nov 10;11(1):192
Cell & bioscience 2021 Nov 10;11(1):192
TRIM15 promotes the invasion and metastasis of pancreatic cancer cells by mediating APOA1 ubiquitination and degradation.
Sun Y, Ren D, Yang C, Yang W, Zhao J, Zhou Y, Jin X, Wu H
Biochimica et biophysica acta. Molecular basis of disease 2021 Nov 1;1867(11):166213
Biochimica et biophysica acta. Molecular basis of disease 2021 Nov 1;1867(11):166213
UFL1 regulates milk protein and fat synthesis-related gene expression of bovine mammary epithelial cells probably via the mTOR signaling pathway.
Li C, Li L, Ali I, Kuang M, Wang X, Wang G
In vitro cellular & developmental biology. Animal 2021 May;57(5):550-559
In vitro cellular & developmental biology. Animal 2021 May;57(5):550-559
Lipoxin A4 protects against paraquat‑induced acute lung injury by inhibiting the TLR4/MyD88‑mediated activation of the NF‑κB and PI3K/AKT pathways.
Li Y, Wang N, Ma Z, Wang Y, Yuan Y, Zhong Z, Hong Y, Zhao M
International journal of molecular medicine 2021 May;47(5)
International journal of molecular medicine 2021 May;47(5)
33-kDa ANXA3 isoform contributes to hepatocarcinogenesis via modulating ERK, PI3K/Akt-HIF and intrinsic apoptosis pathways.
Guo C, Li N, Dong C, Wang L, Li Z, Liu Q, Ma Q, Greenaway FT, Tian Y, Hao L, Liu S, Sun MZ
Journal of advanced research 2021 May;30:85-102
Journal of advanced research 2021 May;30:85-102
GDF11 prevents the formation of thoracic aortic dissection in mice: Promotion of contractile transition of aortic SMCs.
Ren K, Li B, Liu Z, Xia L, Zhai M, Wei X, Duan W, Yu S
Journal of cellular and molecular medicine 2021 May;25(10):4623-4636
Journal of cellular and molecular medicine 2021 May;25(10):4623-4636
Extracellular DJ-1 induces sterile inflammation in the ischemic brain.
Nakamura K, Sakai S, Tsuyama J, Nakamura A, Otani K, Kurabayashi K, Yogiashi Y, Masai H, Shichita T
PLoS biology 2021 May;19(5):e3000939
PLoS biology 2021 May;19(5):e3000939
Ubash3b promotes TPA-mediated suppression of leukemogenesis through accelerated downregulation of PKCδ protein.
Yao Y, Liu W, Gajendran B, Wang C, Zacksenhaus E, Sample KM, Varier KM, Hao X, Ben-David Y
Biochimie 2021 May;184:8-17
Biochimie 2021 May;184:8-17
MicroRNA-628-5p Facilitates Enterovirus 71 Infection by Suppressing TRAF3 Signaling.
Li D, Chen S, Zhang W, Zhang C, Sun T, Du Y, Ding R, Gao Y, Jin Y, Duan G
Cellular & molecular immunology 2021 May;18(5):1320-1322
Cellular & molecular immunology 2021 May;18(5):1320-1322
Zinc-α2-glycoprotein relieved seizure-Induced neuronal glucose uptake impairment via insulin-like growth factor 1 receptor-regulated glucose transporter 3 expression.
Peng W, Liu X, Tan C, Zhou W, Jiang J, Zhou X, Du J, Mo L, Chen L
Journal of neurochemistry 2021 May;157(3):695-709
Journal of neurochemistry 2021 May;157(3):695-709
Danthron ameliorates obesity and MAFLD through activating the interplay between PPARα/RXRα heterodimer and adiponectin receptor 2.
Ma C, Wang Z, Xia R, Wei L, Zhang C, Zhang J, Zhao L, Wu H, Kang L, Yang S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 May;137:111344
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 May;137:111344
Human Cytomegalovirus Uses a Host Stress Response To Balance the Elongation of Saturated/Monounsaturated and Polyunsaturated Very-Long-Chain Fatty Acids.
Xi Y, Lindenmayer L, Kline I, von Einem J, Purdy JG
mBio 2021 May 4;12(3)
mBio 2021 May 4;12(3)
Mechanistic insights into the anti-depressant effect of emodin: an integrated systems pharmacology study and experimental validation.
Zeng P, Wang XM, Ye CY, Su HF, Fang YY, Zhang T, Tian Q
Aging 2021 May 29;13(11):15078-15099
Aging 2021 May 29;13(11):15078-15099
PET-CT and RNA sequencing reveal novel targets for acupuncture-induced lowering of blood pressure in spontaneously hypertensive rats.
Li J, Peng C, Lai D, Fang Y, Luo D, Zhou Z, Li C, Lai X
Scientific reports 2021 May 26;11(1):10973
Scientific reports 2021 May 26;11(1):10973
Induced Pluripotent Stem Cell-Derived Conditioned Medium Promotes Endogenous Leukemia Inhibitory Factor to Attenuate Endotoxin-Induced Acute Lung Injury.
Su VY, Chiou SH, Chen WC, Yu WK, Wu HH, Chen H, Yang KY
International journal of molecular sciences 2021 May 24;22(11)
International journal of molecular sciences 2021 May 24;22(11)
HMGB1 downregulation in retinal pigment epithelial cells protects against diabetic retinopathy through the autophagy-lysosome pathway.
Feng L, Liang L, Zhang S, Yang J, Yue Y, Zhang X
Autophagy 2021 May 24;:1-20
Autophagy 2021 May 24;:1-20
The novel prognostic risk factor STC2 can regulate the occurrence and progression of osteosarcoma via the glycolytic pathway.
Yu B, Zhang F, Liu L, Liang Y, Tang X, Peng Y, Cai F, Zeng D, Yuan X, Li J, Guo Y, Lv B, Wang M, Liao Q, Lv XB
Biochemical and biophysical research communications 2021 May 21;554:25-32
Biochemical and biophysical research communications 2021 May 21;554:25-32
Essential Role of CRIM1 on Endometrial Receptivity in Goat.
Yang D, Liu A, Zhang Y, Nan S, Yin R, Lei Q, Zhu H, Chen J, Han L, Ding M, Ding Y
International journal of molecular sciences 2021 May 18;22(10)
International journal of molecular sciences 2021 May 18;22(10)
Differentially expressed genes induced by β-caryophyllene in a rat model of cerebral ischemia-reperfusion injury.
Liu S, Liu J, Wang Y, Deng L, Chen S, Wang X, Zuo T, Hu Q, Rao J, Wang Q, Dong Z
Life sciences 2021 May 15;273:119293
Life sciences 2021 May 15;273:119293
Protective effect of recombinant Lactobacillus plantarum against H2O2-induced oxidative stress in HUVEC cells.
Wang G, Hao M, Liu Q, Jiang Y, Huang H, Yang G, Wang C
Journal of Zhejiang University. Science. B 2021 May 15;22(5):348-365
Journal of Zhejiang University. Science. B 2021 May 15;22(5):348-365
The HDAC and PI3K dual inhibitor CUDC-907 synergistically enhances the antileukemic activity of venetoclax in preclinical models of acute myeloid leukemia.
Li X, Su Y, Hege K, Madlambayan G, Edwards H, Knight T, Polin L, Kushner J, Dzinic SH, White K, Yang J, Miller R, Wang G, Zhao L, Wang Y, Lin H, Taub JW, Ge Y
Haematologica 2021 May 1;106(5):1262-1277
Haematologica 2021 May 1;106(5):1262-1277
Glucagon-like peptide-1 (GLP-1) improved diabetic lung fibrosis via AMPK and microRNA-27a (miR-27a).
Liu J, Li X, Lu S, Zheng X, Zhang X, Zhao W
Annals of translational medicine 2021 Mar;9(6):492
Annals of translational medicine 2021 Mar;9(6):492
Angiotensin II-mediated improvement of renal mitochondrial function via the AMPK/PGC-1α/NRF-2 pathway is superior to norepinephrine in a rat model of septic shock associated with acute renal injury.
An H, Hu Z, Chen Y, Cheng L, Shi J, Han L
Annals of translational medicine 2021 Mar;9(6):481
Annals of translational medicine 2021 Mar;9(6):481
Low expression of BTN3A3 indicates poor prognosis and promotes cell proliferation, migration and invasion in non-small cell lung cancer.
Cheng X, Ma T, Yi L, Su C, Wang X, Wen T, Wang B, Wang Y, Zhang H, Liu Z
Annals of translational medicine 2021 Mar;9(6):478
Annals of translational medicine 2021 Mar;9(6):478
Protein kinase D participates in cardiomyocyte hypertrophy by regulating extracellular signal-regulated and myocyte enhancer factor 2D.
Yuan H, Xiang Q, Yang L, Geng J
Revista portuguesa de cardiologia 2021 Mar;40(3):191-200
Revista portuguesa de cardiologia 2021 Mar;40(3):191-200
The novel ALK inhibitor ZX-29 induces apoptosis through inhibiting ALK and inducing ROS-mediated endoplasmic reticulum stress in Karpas299 cells.
Zhou X, Zhang X, Wu Z, Xu X, Guo M, Zhai X, Zuo D, Wu Y
Journal of biochemical and molecular toxicology 2021 Mar;35(3):e22666
Journal of biochemical and molecular toxicology 2021 Mar;35(3):e22666
Effects of photoperiod on morphology and function in testis and epididymis of Cricetulus barabensis.
Mou J, Xu J, Wang Z, Wang C, Yang X, Wang X, Xue H, Wu M, Xu L
Journal of cellular physiology 2021 Mar;236(3):2109-2125
Journal of cellular physiology 2021 Mar;236(3):2109-2125
Resveratrol induces human colorectal cancer cell apoptosis by activating the mitochondrial pathway via increasing reactive oxygen species.
Fu Y, Ye Y, Zhu G, Xu Y, Sun J, Wu H, Feng F, Wen Z, Jiang S, Li Y, Zhang Q
Molecular medicine reports 2021 Mar;23(3)
Molecular medicine reports 2021 Mar;23(3)
Curcumin suppresses colorectal tumorigenesis via the Wnt/β-catenin signaling pathway by downregulating Axin2.
Hao J, Dai X, Gao J, Li Y, Hou Z, Chang Z, Wang Y
Oncology letters 2021 Mar;21(3):186
Oncology letters 2021 Mar;21(3):186
MALAT1 sponges miR-26a and miR-26b to regulate endothelial cell angiogenesis via PFKFB3-driven glycolysis in early-onset preeclampsia.
Li Q, Liu X, Liu W, Zhang Y, Wu M, Chen Z, Zhao Y, Zou L
Molecular therapy. Nucleic acids 2021 Mar 5;23:897-907
Molecular therapy. Nucleic acids 2021 Mar 5;23:897-907
TDP-43 and PINK1 mediate CHCHD10S59L mutation-induced defects in Drosophila and in vitro.
Baek M, Choe YJ, Bannwarth S, Kim J, Maitra S, Dorn GW 2nd, Taylor JP, Paquis-Flucklinger V, Kim NC
Nature communications 2021 Mar 26;12(1):1924
Nature communications 2021 Mar 26;12(1):1924
The combination of G-CSF and AMD3100 mobilizes bone marrow-derived stem cells to protect against cisplatin-induced acute kidney injury in mice.
Chen Z, Ren X, Ren R, Wang Y, Shang J
Stem cell research & therapy 2021 Mar 24;12(1):209
Stem cell research & therapy 2021 Mar 24;12(1):209
GR/NF-κB signaling pathway regulates hippocampal inflammatory responses in diabetic rats with chronic unpredictable mild stress.
Li ZR, Han YS, Liu Z, Zhao HQ, Liu J, Yang H, Wang YH
European journal of pharmacology 2021 Mar 15;895:173861
European journal of pharmacology 2021 Mar 15;895:173861
Exposure to Melamine cyanuric acid in adolescent mice caused emotional disorder and behavioral disorder.
Wang S, Zhang J, Zhang S, Shi F, Feng D, Feng X
Ecotoxicology and environmental safety 2021 Mar 15;211:111938
Ecotoxicology and environmental safety 2021 Mar 15;211:111938
Identification and functional analysis of senescence-associated secretory phenotype of premature senescent hepatocytes induced by hexavalent chromium.
Ma Y, Liang Y, Liang N, Zhang Y, Xiao F
Ecotoxicology and environmental safety 2021 Mar 15;211:111908
Ecotoxicology and environmental safety 2021 Mar 15;211:111908
Overexpression of Annexin A2 promotes proliferation by forming a Glypican 1/c-Myc positive feedback loop: prognostic significance in human glioma.
Li X, Nie S, Lv Z, Ma L, Song Y, Hu Z, Hu X, Liu Z, Zhou G, Dai Z, Song T, Liu J, Wang S
Cell death & disease 2021 Mar 12;12(3):261
Cell death & disease 2021 Mar 12;12(3):261
Dietary seaweed-derived polysaccharides improve growth performance of weaned pigs through maintaining intestinal barrier function and modulating gut microbial populations.
Zou T, Yang J, Guo X, He Q, Wang Z, You J
Journal of animal science and biotechnology 2021 Mar 10;12(1):28
Journal of animal science and biotechnology 2021 Mar 10;12(1):28
Dihydroxyeicosatrienoic Acid, a Metabolite of Epoxyeicosatrienoic Acids Upregulates Endothelial Nitric Oxide Synthase Expression Through Transcription: Mechanism of Vascular Endothelial Function Protection.
Zuo D, Pi Q, Shi Y, Luo S, Xia Y
Cell biochemistry and biophysics 2021 Jun;79(2):289-299
Cell biochemistry and biophysics 2021 Jun;79(2):289-299
CLIC1 Inhibition Protects Against Cellular Senescence and Endothelial Dysfunction Via the Nrf2/HO-1 Pathway.
Lu D, Le Y, Ding J, Dou X, Mao W, Zhu J
Cell biochemistry and biophysics 2021 Jun;79(2):239-252
Cell biochemistry and biophysics 2021 Jun;79(2):239-252
Prenatal High-Sucrose Diet Induced Vascular Dysfunction in Thoracic Artery of Fetal Offspring.
Feng X, Yu T, Zhang Y, Li L, Qu M, Wang J, Dong F, Zhang L, Wang F, Zhang F, Zhou X, Xu Z, Man D
Molecular nutrition & food research 2021 Jun;65(12):e2100072
Molecular nutrition & food research 2021 Jun;65(12):e2100072
Targeting the p300/NONO axis sensitizes melanoma cells to BRAF inhibitors.
Zhang F, Tang X, Fan S, Liu X, Sun J, Ju C, Liang Y, Liu R, Zhou R, Yu B, Zhang C, Zhang Z, Kang T, Huang G, Lv XB
Oncogene 2021 Jun;40(24):4137-4150
Oncogene 2021 Jun;40(24):4137-4150
Interleukin-1 induces receptor activator of nuclear factor-κB ligand-independent osteoclast differentiation in RAW264.7 cells.
Liao R, Feng Z, Li W, Liu R, Xu X, Yao S, Tian J
Experimental and therapeutic medicine 2021 Jun;21(6):640
Experimental and therapeutic medicine 2021 Jun;21(6):640
The Role of Nrf2 on the Cognitive Dysfunction of High-fat Diet Mice Following Lead Exposure.
Zhang L, Bo J, Chen W, Li S, Wang Y, Yan L, Wu L, Zhang Y
Biological trace element research 2021 Jun;199(6):2247-2258
Biological trace element research 2021 Jun;199(6):2247-2258
Isolation, characterization and transcriptome analysis of porcine deltacoronavirus strain HNZK-02 from Henan Province, China.
Jin XH, Zhang YF, Yuan YX, Han L, Zhang GP, Hu H
Molecular immunology 2021 Jun;134:86-99
Molecular immunology 2021 Jun;134:86-99
Melatonin inhibits lipid accumulation to repress prostate cancer progression by mediating the epigenetic modification of CES1.
Zhou L, Zhang C, Yang X, Liu L, Hu J, Hou Y, Tao H, Sugimura H, Chen Z, Wang L, Chen K
Clinical and translational medicine 2021 Jun;11(6):e449
Clinical and translational medicine 2021 Jun;11(6):e449
Hydrogen sulfide alleviates apoptosis and autophagy induced by beryllium sulfate in 16HBE cells.
Liu YP, Yuan XY, Li XY, Wang Y, Sun ZB, Deng WH, Lei YD, Huang L, Jiang TY, Zhang ZH
Journal of applied toxicology : JAT 2021 Jun 6;
Journal of applied toxicology : JAT 2021 Jun 6;
Endoplasmic reticulum stress manipulates autophagic response that antagonizes polybrominated diphenyl ethers quinone induced cytotoxicity in microglial BV2 cells.
Zhu Q, Liu Z, Wang Y, Song E, Song Y
Journal of hazardous materials 2021 Jun 5;411:124958
Journal of hazardous materials 2021 Jun 5;411:124958
LINC00511 drives invasive behavior in hepatocellular carcinoma by regulating exosome secretion and invadopodia formation.
Peng X, Li X, Yang S, Huang M, Wei S, Ma Y, Li Y, Wu B, Jin H, Li B, Tang S, Fan Q, Liu J, Yang L, Li H
Journal of experimental & clinical cancer research : CR 2021 Jun 4;40(1):183
Journal of experimental & clinical cancer research : CR 2021 Jun 4;40(1):183
YTHDF1 promotes hepatocellular carcinoma progression via activating PI3K/AKT/mTOR signaling pathway and inducing epithelial-mesenchymal transition.
Luo X, Cao M, Gao F, He X
Experimental hematology & oncology 2021 Jun 4;10(1):35
Experimental hematology & oncology 2021 Jun 4;10(1):35
A metabolic data-driven systems pharmacology strategy for decoding and validating the mechanism of Compound Kushen Injection against HCC.
Wang KX, Chen YP, Lu AP, Du GH, Qin XM, Guan DG, Gao L
Journal of ethnopharmacology 2021 Jun 28;274:114043
Journal of ethnopharmacology 2021 Jun 28;274:114043
Hsa_circ_0008234 facilitates proliferation of cutaneous squamous cell carcinoma through targeting miR-127-5p to regulate ADCY7.
Cai L, Wang Y, Wu J, Wu G
Archives of dermatological research 2021 Jun 18;
Archives of dermatological research 2021 Jun 18;
Antiviral effects of ergosterol peroxide in a pig model of porcine deltacoronavirus (PDCoV) infection involves modulation of apoptosis and tight junction in the small intestine.
Duan C, Wang J, Liu Y, Zhang J, Si J, Hao Z, Wang J
Veterinary research 2021 Jun 14;52(1):86
Veterinary research 2021 Jun 14;52(1):86
Effects of total flavonoids from Eucommia ulmoides Oliv. leaves on polycystic ovary syndrome with insulin resistance model rats induced by letrozole combined with a high-fat diet.
Peng MF, Tian S, Song YG, Li CX, Miao MS, Ren Z, Li M
Journal of ethnopharmacology 2021 Jun 12;273:113947
Journal of ethnopharmacology 2021 Jun 12;273:113947
CENPE contributes to pulmonary vascular remodeling in pulmonary hypertension.
Fang X, Xie M, Liu X, He Y
Biochemical and biophysical research communications 2021 Jun 11;557:40-47
Biochemical and biophysical research communications 2021 Jun 11;557:40-47
Insulin injections inhibits PTZ-induced mitochondrial dysfunction, oxidative stress and neurological deficits via the SIRT1/PGC-1α/SIRT3 pathway.
Cheng Y, Zeng X, Mai Q, Bai X, Jiang Y, Li J, Fan S, Ding H
Biochimica et biophysica acta. Molecular basis of disease 2021 Jun 1;1867(6):166124
Biochimica et biophysica acta. Molecular basis of disease 2021 Jun 1;1867(6):166124
Diosmetin ameliorate type 2 diabetic mellitus by up-regulating Corynebacterium glutamicum to regulate IRS/PI3K/AKT-mediated glucose metabolism disorder in KK-Ay mice.
Gong X, Xiong L, Bi C, Zhang B
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Jul;87:153582
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Jul;87:153582
PI3K/AKT pathway mediates the antidepressant- and anxiolytic-like roles of hydrogen sulfide in streptozotocin-induced diabetic rats via promoting hippocampal neurogenesis.
Jiang W, Tang YY, Zhu WW, Li C, Zhang P, Li RQ, Chen YJ, Zou W, Tang XQ
Neurotoxicology 2021 Jul;85:201-208
Neurotoxicology 2021 Jul;85:201-208
Cathepsin K deficiency promotes alveolar bone regeneration by promoting jaw bone marrow mesenchymal stem cells proliferation and differentiation via glycolysis pathway.
Zhang W, Dong Z, Li D, Li B, Liu Y, Zheng X, Liu H, Zhou H, Hu K, Xue Y
Cell proliferation 2021 Jul;54(7):e13058
Cell proliferation 2021 Jul;54(7):e13058
HORMAD1 promotes docetaxel resistance in triple negative breast cancer by enhancing DNA damage tolerance.
Zong B, Sun L, Peng Y, Wang Y, Yu Y, Lei J, Zhang Y, Guo S, Li K, Liu S
Oncology reports 2021 Jul;46(1)
Oncology reports 2021 Jul;46(1)
Hypoxic acclimation improves cardiac redox homeostasis and protects heart against ischemia-reperfusion injury through upregulation of O-GlcNAcylation.
Ou W, Liang Y, Qin Y, Wu W, Xie M, Zhang Y, Zhang Y, Ji L, Yu H, Li T
Redox biology 2021 Jul;43:101994
Redox biology 2021 Jul;43:101994
The SESAME complex regulates cell senescence through the generation of acetyl-CoA.
Chen W, Yu X, Wu Y, Tang J, Yu Q, Lv X, Zha Z, Hu B, Li X, Chen J, Ma L, Workman JL, Li S
Nature metabolism 2021 Jul;3(7):983-1000
Nature metabolism 2021 Jul;3(7):983-1000
Advanced maternal age causes premature placental senescence and malformation via dysregulated α-Klotho expression in trophoblasts.
Chen Z, Xiong L, Jin H, Yu J, Li X, Fu H, Wen L, Qi H, Tong C, Saffery R, Kilby MD, Baker PN
Aging cell 2021 Jul;20(7):e13417
Aging cell 2021 Jul;20(7):e13417
SPOP negatively regulates Toll-like receptor-induced inflammation by disrupting MyD88 self-association.
Hu YH, Wang Y, Wang F, Dong YM, Jiang WL, Wang YP, Zhong X, Ma LX
Cellular & molecular immunology 2021 Jul;18(7):1708-1717
Cellular & molecular immunology 2021 Jul;18(7):1708-1717
Medioresinol as a novel PGC-1α activator prevents pyroptosis of endothelial cells in ischemic stroke through PPARα-GOT1 axis.
Wang Y, Guan X, Gao CL, Ruan W, Zhao S, Kai G, Li F, Pang T
Pharmacological research 2021 Jul;169:105640
Pharmacological research 2021 Jul;169:105640
Resveratrol attenuates manganese-induced oxidative stress and neuroinflammation through SIRT1 signaling in mice.
Cong L, Lei MY, Liu ZQ, Liu ZF, Ma Z, Liu K, Li J, Deng Y, Liu W, Xu B
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Jul;153:112283
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Jul;153:112283
Shenmai injection improves doxorubicin cardiotoxicity via miR-30a/Beclin 1.
Zhang X, Lv S, Zhang W, Jia Q, Wang L, Ding Y, Yuan P, Zhu Y, Liu L, Li Y, Zhang J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jul;139:111582
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jul;139:111582
Upregulation of RNA cap methyltransferase RNMT drives ribosome biogenesis during T cell activation.
Galloway A, Kaskar A, Ditsova D, Atrih A, Yoshikawa H, Gomez-Moreira C, Suska O, Warminski M, Grzela R, Lamond AI, Darzynkiewicz E, Jemielity J, Cowling VH
Nucleic acids research 2021 Jul 9;49(12):6722-6738
Nucleic acids research 2021 Jul 9;49(12):6722-6738
Anoctamin 5 promotes osteosarcoma development by increasing degradation of Nel-like proteins 1 and 2.
Pan R, Lu Q, Ren C, Li H, Zeng F, Tian X, Chen H
Aging 2021 Jul 9;13(13):17316-17327
Aging 2021 Jul 9;13(13):17316-17327
Giardia duodenalis extracellular vesicles regulate the proinflammatory immune response in mouse macrophages in vitro via the MAPK, AKT and NF-κB pathways.
Zhao P, Cao L, Wang X, Li J, Dong J, Zhang N, Li X, Li S, Sun M, Zhang X, Liang M, Pu X, Gong P
Parasites & vectors 2021 Jul 8;14(1):358
Parasites & vectors 2021 Jul 8;14(1):358
miR-126 Controls the Apoptosis and Proliferation of Immature Porcine Sertoli Cells by Targeting the PIK3R2 Gene through the PI3K/AKT Signaling Pathway.
Tang X, Chen Y, Luo H, Bian Q, Weng B, Yang A, Chu D, Ran M, Chen B
Animals : an open access journal from MDPI 2021 Jul 30;11(8)
Animals : an open access journal from MDPI 2021 Jul 30;11(8)
Tumor protein D52 is upregulated in oral squamous carcinoma cells under hypoxia in a hypoxia-inducible-factor-independent manner and is involved in cell death resistance.
Abe Y, Mukudai Y, Kurihara M, Houri A, Chikuda J, Yaso A, Kato K, Shimane T, Shirota T
Cell & bioscience 2021 Jul 3;11(1):122
Cell & bioscience 2021 Jul 3;11(1):122
A novel chemical inhibitor suppresses breast cancer cell growth and metastasis through inhibiting HPIP oncoprotein.
Li P, Cao S, Huang Y, Zhang Y, Liu J, Cai X, Zhou L, Li J, Jiang Z, Ding L, Zheng Z, Li S, Ye Q
Cell death discovery 2021 Jul 29;7(1):198
Cell death discovery 2021 Jul 29;7(1):198
Zinc Alleviates Arsenic-Induced Inflammation and Apoptosis in the Head Kidney of Common Carp by Inhibiting Oxidative Stress and Endoplasmic Reticulum Stress.
Xing P, Zhang Y, Chi Q, Li S
Biological trace element research 2021 Jul 21;
Biological trace element research 2021 Jul 21;
UHRF2 commissions the completion of DNA demethylation through allosteric activation by 5hmC and K33-linked ubiquitination of XRCC1.
Liu X, Xu B, Yang J, He L, Zhang Z, Cheng X, Yu H, Liu X, Jin T, Peng Y, Huang Y, Xia L, Wang Y, Wu J, Wu X, Liu S, Shan L, Yang X, Sun L, Liang J, Zhang Y, Shang Y
Molecular cell 2021 Jul 15;81(14):2960-2974.e7
Molecular cell 2021 Jul 15;81(14):2960-2974.e7
A clinically acceptable strategy for sensitizing anti-PD-1 treatment by hypoxia relief.
Jiang M, Qin B, Luo L, Li X, Shi Y, Zhang J, Luo Z, Zhu C, Guan G, Du Y, You J
Journal of controlled release : official journal of the Controlled Release Society 2021 Jul 10;335:408-419
Journal of controlled release : official journal of the Controlled Release Society 2021 Jul 10;335:408-419
Neuroinflammation induces anxiety- and depressive-like behavior by modulating neuronal plasticity in the basolateral amygdala.
Zheng ZH, Tu JL, Li XH, Hua Q, Liu WZ, Liu Y, Pan BX, Hu P, Zhang WH
Brain, behavior, and immunity 2021 Jan;91:505-518
Brain, behavior, and immunity 2021 Jan;91:505-518
Limonin ameliorates dextran sulfate sodium-induced chronic colitis in mice by inhibiting PERK-ATF4-CHOP pathway of ER stress and NF-κB signaling.
Song C, Chen J, Li X, Yang R, Cao X, Zhou L, Zhou Y, Ying H, Zhang Q, Sun Y
International immunopharmacology 2021 Jan;90:107161
International immunopharmacology 2021 Jan;90:107161
Sunitinib malate inhibits intestinal tumor development in male ApcMin/+ mice by down-regulating inflammation-related factors with suppressing β-cateinin/c-Myc pathway and re-balancing Bcl-6 and Caspase-3.
Chen L, Xu P, Xiao Q, Chen L, Li S, Jian JM, Zhong YB
International immunopharmacology 2021 Jan;90:107128
International immunopharmacology 2021 Jan;90:107128
Astragaloside IV inhibits cell proliferation and metastasis of breast cancer via promoting the long noncoding RNA TRHDE-AS1.
Hu S, Zheng W, Jin L
Journal of natural medicines 2021 Jan;75(1):156-166
Journal of natural medicines 2021 Jan;75(1):156-166
A novel peptide relieves endothelial cell dysfunction in preeclampsia by regulating the PI3K/mTOR/HIF1α pathway.
Xue L, Xie K, Wu L, Yu X, Long W, Li C, Jia R, Ding H
International journal of molecular medicine 2021 Jan;47(1):276-288
International journal of molecular medicine 2021 Jan;47(1):276-288
MSH6 Aggravates the Hypoxic Microenvironment via Regulating HIF1A to Promote the Metastasis of Glioblastoma Multiforme.
Shi Y, Jiang J, Cui Y, Chen Y, Dong T, An H, Liu P
DNA and cell biology 2021 Jan;40(1):93-100
DNA and cell biology 2021 Jan;40(1):93-100
Mefunidone ameliorates diabetic kidney disease in STZ and db/db mice.
Jiang Y, Xie F, Lv X, Wang S, Liao X, Yu Y, Dai Q, Zhang Y, Meng J, Hu G, Peng Z, Tao L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Jan;35(1):e21198
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Jan;35(1):e21198
Evaluation of piggyBac-mediated anti-CD19 CAR-T cells after ex vivo expansion with aAPCs or magnetic beads.
Yang LR, Li L, Meng MY, Wang WJ, Yang SL, Zhao YY, Wang RQ, Gao H, Tang WW, Yang Y, Yang LL, Liao LW, Hou ZL
Journal of cellular and molecular medicine 2021 Jan;25(2):686-700
Journal of cellular and molecular medicine 2021 Jan;25(2):686-700
Carbohydrate response element-binding protein regulates lipid metabolism via mTOR complex1 in diabetic nephropathy.
Chen N, Mu L, Yang Z, Du C, Wu M, Song S, Yuan C, Shi Y
Journal of cellular physiology 2021 Jan;236(1):625-640
Journal of cellular physiology 2021 Jan;236(1):625-640
Bone marrow stem cells therapy alleviates vascular injury in a chronic obstructive pulmonary disease‑obstructive sleep apnea overlap syndrome rat model.
Bi H, He J, He X, Du J, Chen M, Huang Z, Yang C, Yang L, Li H, Zhou K, Wang Q, He L, Jin Z
Molecular medicine reports 2021 Jan;23(1)
Molecular medicine reports 2021 Jan;23(1)
Induction of autophagy by Beclin-1 in granulosa cells contributes to follicular progesterone elevation in ovarian endometriosis.
Ding Y, Zhu Q, He Y, Lu Y, Wang Y, Qi J, Wu H, Xu R, Li J, Li X, Sun Y
Translational research : the journal of laboratory and clinical medicine 2021 Jan;227:15-29
Translational research : the journal of laboratory and clinical medicine 2021 Jan;227:15-29
Protective effect of naringenin against cadmium-induced testicular toxicity in male SD rats.
Wang J, Zhu H, Lin S, Wang K, Wang H, Liu Z
Journal of inorganic biochemistry 2021 Jan;214:111310
Journal of inorganic biochemistry 2021 Jan;214:111310
The cGAS-STING signaling pathway contributes to the inflammatory response and autophagy in Aspergillus fumigatus keratitis.
Han F, Guo H, Wang L, Zhang Y, Sun L, Dai C, Wu X
Experimental eye research 2021 Jan;202:108366
Experimental eye research 2021 Jan;202:108366
EPZ015666, a selective protein arginine methyltransferase 5 (PRMT5) inhibitor with an antitumour effect in retinoblastoma.
Liu X, He J, Mao L, Zhang Y, Cui W, Duan S, Jiang A, Gao Y, Sang Y, Huang G
Experimental eye research 2021 Jan;202:108286
Experimental eye research 2021 Jan;202:108286
IKKβ activation promotes amphisome formation and extracellular vesicle secretion in tumor cells.
Peng X, Yang L, Ma Y, Li X, Yang S, Li Y, Wu B, Tang S, Zhang F, Zhang B, Liu J, Li H
Biochimica et biophysica acta. Molecular cell research 2021 Jan;1868(1):118857
Biochimica et biophysica acta. Molecular cell research 2021 Jan;1868(1):118857
Trichostatin A increases BDNF protein expression by improving XBP-1s/ATF6/GRP78 axis in Schwann cells of diabetic peripheral neuropathy.
An J, Zhang X, Jia K, Zhang C, Zhu L, Cheng M, Li F, Zhao S, Hao J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jan;133:111062
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jan;133:111062
Hypoxia-induced FOXO4/LDHA axis modulates gastric cancer cell glycolysis and progression.
Wang XH, Jiang ZH, Yang HM, Zhang Y, Xu LH
Clinical and translational medicine 2021 Jan;11(1):e279
Clinical and translational medicine 2021 Jan;11(1):e279
A Cas9-transcription factor fusion protein enhances homology-directed repair efficiency.
Li G, Wang H, Zhang X, Wu Z, Yang H
The Journal of biological chemistry 2021 Jan-Jun;296:100525
The Journal of biological chemistry 2021 Jan-Jun;296:100525
Huaier Inhibits Proliferation, Migration, and Invasion of Cutaneous Squamous Cell Carcinoma Cells by Inhibiting the Methylation Levels of CDKN2A and TP53.
Wang L, Xu L, Wang Y
Integrative cancer therapies 2021 Jan-Dec;20:15347354211031646
Integrative cancer therapies 2021 Jan-Dec;20:15347354211031646
ING5 Inhibits Migration and Invasion of Esophageal Cancer Cells by Downregulating the IL-6/CXCL12 Signaling Pathway.
Wang Y, Tan J, Li J, Chen H, Wang W
Technology in cancer research & treatment 2021 Jan-Dec;20:15330338211039940
Technology in cancer research & treatment 2021 Jan-Dec;20:15330338211039940
Obacunone Attenuates Liver Fibrosis with Enhancing Anti-Oxidant Effects of GPx-4 and Inhibition of EMT.
Bai Y, Wang W, Wang L, Ma L, Zhai D, Wang F, Shi R, Liu C, Xu Q, Chen G, Lu Z
Molecules (Basel, Switzerland) 2021 Jan 9;26(2)
Molecules (Basel, Switzerland) 2021 Jan 9;26(2)
TRIM21-regulated Annexin A2 plasma membrane trafficking facilitates osteosarcoma cell differentiation through the TFEB-mediated autophagy.
Zhang HT, Zeng Q, Wu B, Lu J, Tong KL, Lin J, Liu QY, Xu L, Yang J, Liu X, Liu W, Zhang YF, Lian Q, Liu L, Gao X
Cell death & disease 2021 Jan 6;12(1):21
Cell death & disease 2021 Jan 6;12(1):21
Nrf2 overexpression increases risk of high tumor mutation burden in acute myeloid leukemia by inhibiting MSH2.
Liu P, Ma D, Wang P, Pan C, Fang Q, Wang J
Cell death & disease 2021 Jan 5;12(1):20
Cell death & disease 2021 Jan 5;12(1):20
Sterol and oxysterol synthases near the ciliary base activate the Hedgehog pathway.
Findakly S, Daggubati V, Garcia G, LaStella SA, Choudhury A, Tran C, Li A, Tong P, Garcia JQ, Puri N, Reiter JF, Xu L, Raleigh DR
The Journal of cell biology 2021 Jan 4;220(1)
The Journal of cell biology 2021 Jan 4;220(1)
Autophagy impairment as a key feature for acetaminophen-induced ototoxicity.
Zhao T, Zheng T, Yu H, Hu BH, Hu B, Ma P, Yang Y, Yang N, Hu J, Cao T, Chen G, Yan B, Peshoff M, Hatzoglou M, Geng R, Li B, Zheng QY
Cell death & disease 2021 Jan 4;12(1):3
Cell death & disease 2021 Jan 4;12(1):3
Formaldehyde induces ferroptosis in hippocampal neuronal cells by upregulation of the Warburg effect.
Li XN, Yang SQ, Li M, Li XS, Tian Q, Xiao F, Tang YY, Kang X, Wang CY, Zou W, Zhang P, Tang XQ
Toxicology 2021 Jan 30;448:152650
Toxicology 2021 Jan 30;448:152650
Fucoxanthin extracted from Laminaria Japonica inhibits metastasis and enhances the sensitivity of lung cancer to Gefitinib.
Ming JX, Wang ZC, Huang Y, Ohishi H, Wu RJ, Shao Y, Wang H, Qin MY, Wu ZL, Li YY, Chang Zhou S, Chen H, Liu H, Xu R
Journal of ethnopharmacology 2021 Jan 30;265:113302
Journal of ethnopharmacology 2021 Jan 30;265:113302
A deafness-associated tRNA mutation caused pleiotropic effects on the m1G37 modification, processing, stability and aminoacylation of tRNAIle and mitochondrial translation.
Meng F, Zhou M, Xiao Y, Mao X, Zheng J, Lin J, Lin T, Ye Z, Cang X, Fu Y, Wang M, Guan MX
Nucleic acids research 2021 Jan 25;49(2):1075-1093
Nucleic acids research 2021 Jan 25;49(2):1075-1093
Circ-NOLC1 promotes epithelial ovarian cancer tumorigenesis and progression by binding ESRP1 and modulating CDK1 and RhoA expression.
Chen S, Wu W, Li QH, Xie BM, Shen F, Du YP, Zong ZH, Wang LL, Wei XQ, Zhao Y
Cell death discovery 2021 Jan 22;7(1):22
Cell death discovery 2021 Jan 22;7(1):22
Cdk5-Mediated Phosphorylation of Sirt1 Contributes to Podocyte Mitochondrial Dysfunction in Diabetic Nephropathy.
Wang S, Yang Y, He X, Yang L, Wang J, Xia S, Liu D, Liu S, Yang L, Liu W, Duan H
Antioxidants & redox signaling 2021 Jan 20;34(3):171-190
Antioxidants & redox signaling 2021 Jan 20;34(3):171-190
A key role of gut microbiota-vagus nerve/spleen axis in sleep deprivation-mediated aggravation of systemic inflammation after LPS administration.
Zhang Y, Xie B, Chen X, Zhang J, Yuan S
Life sciences 2021 Jan 15;265:118736
Life sciences 2021 Jan 15;265:118736
Let-7a regulates EV secretion and mitochondrial oxidative phosphorylation by targeting SNAP23 in colorectal cancer.
Liu YD, Zhuang XP, Cai DL, Cao C, Gu QS, Liu XN, Zheng BB, Guan BJ, Yu L, Li JK, Ding HB, Yan DW
Journal of experimental & clinical cancer research : CR 2021 Jan 14;40(1):31
Journal of experimental & clinical cancer research : CR 2021 Jan 14;40(1):31
Bushen Huoxue recipe attenuates early pregnancy loss via activating endometrial COX2-PGE2 angiogenic signaling in mice.
Song Y, Zhou F, Tan X, Liu X, Ding J, Zhang C, Li F, Zhu W, Ma W, Hu R, Zhang M
BMC complementary medicine and therapies 2021 Jan 14;21(1):36
BMC complementary medicine and therapies 2021 Jan 14;21(1):36
CDCA4 suppresses epithelial-mesenchymal transtion (EMT) and metastasis in Non-small cell lung cancer through modulating autophagy.
Xu C, Cao H, Sui Y, Zhang H, Shi C, Wu J, Ma R, Feng J
Cancer cell international 2021 Jan 12;21(1):48
Cancer cell international 2021 Jan 12;21(1):48
L-type amino acid transporter 1 is associated with chemoresistance in breast cancer via the promotion of amino acid metabolism.
Sato M, Harada-Shoji N, Toyohara T, Soga T, Itoh M, Miyashita M, Tada H, Amari M, Anzai N, Furumoto S, Abe T, Suzuki T, Ishida T, Sasano H
Scientific reports 2021 Jan 12;11(1):589
Scientific reports 2021 Jan 12;11(1):589
Changes in the prefrontal cortex after the hippocampus was injected with Aβ25-35 via the P35/P25-CDK5-Tau hyperphosphorylation signaling pathway.
Wang Y, Sheng H, Zhao J, Guo L, Liu J, Xu J, Liu Q, Huang J, Jiang R, Gan S, Qiu G, Lu W, Xu S, Zhu S
Neuroscience letters 2021 Jan 10;741:135453
Neuroscience letters 2021 Jan 10;741:135453
Eradicating intracellular MRSA via targeted delivery of lysostaphin and vancomycin with mannose-modified exosomes.
Yang X, Xie B, Peng H, Shi G, Sreenivas B, Guo J, Wang C, He Y
Journal of controlled release : official journal of the Controlled Release Society 2021 Jan 10;329:454-467
Journal of controlled release : official journal of the Controlled Release Society 2021 Jan 10;329:454-467
Metformin alleviates high glucose-induced ER stress and inflammation by inhibiting the interaction between caveolin1 and AMPKα in rat astrocytes.
Wang G, Cui W, Chen S, Shao Z, Li Y, Wang W, Mao L, Li J, Mei X
Biochemical and biophysical research communications 2021 Jan 1;534:908-913
Biochemical and biophysical research communications 2021 Jan 1;534:908-913
ActivinA activates Notch1-Shh signaling to regulate proliferation in C2C12 skeletal muscle cells.
Ma L, Li C, Lian S, Xu B, Yuan J, Lu J, Yang H, Guo J, Ji H
Molecular and cellular endocrinology 2021 Jan 1;519:111055
Molecular and cellular endocrinology 2021 Jan 1;519:111055
Disrupted eNOS activity and expression account for vasodilator dysfunction in different stage of sepsis.
Hu S, Pi Q, Xu X, Yan J, Guo Y, Tan W, He A, Cheng Z, Luo S, Xia Y
Life sciences 2021 Jan 1;264:118606
Life sciences 2021 Jan 1;264:118606
Anti-renal interstitial fibrosis effect of norcantharidin is exerted through inhibition of PP2Ac-mediated C-terminal phosphorylation of Smad3.
Luo HW, Yin DD, Xiao Z, Wen L, Liao YJ, Tang CY, Zeng D, Xiao HT, Li Y
Chemical biology & drug design 2021 Feb;97(2):293-304
Chemical biology & drug design 2021 Feb;97(2):293-304
Syndecan 4 contributes to osteoclast differentiation induced by RANKL through enhancing autophagy.
Li J, Sun Z, Lin Y, Yan Y, Yan H, Jing B, Han Z
International immunopharmacology 2021 Feb;91:107275
International immunopharmacology 2021 Feb;91:107275
Type 1 interferon aggravates lipopolysaccharide-induced sepsis through upregulating Caspase-11 and Gasdermin D.
Wang Y, Zhang X, Guo Y, Li X, Guo G, Niu Z, Zhang J
Journal of physiology and biochemistry 2021 Feb;77(1):85-92
Journal of physiology and biochemistry 2021 Feb;77(1):85-92
Effect of claudin 1 on cell proliferation, migration and apoptosis in human cervical squamous cell carcinoma.
Shen Z, Song W, Qian L, Zhu J, Li Y, Li M, Zhang T, Zhao W, Zhou Y, Yang X
Oncology reports 2021 Feb;45(2):606-618
Oncology reports 2021 Feb;45(2):606-618
Sodium alginate/collagen hydrogel loaded with human umbilical cord mesenchymal stem cells promotes wound healing and skin remodeling.
Zhang Z, Li Z, Li Y, Wang Y, Yao M, Zhang K, Chen Z, Yue H, Shi J, Guan F, Ma S
Cell and tissue research 2021 Feb;383(2):809-821
Cell and tissue research 2021 Feb;383(2):809-821
Downregulating lncRNA PRNCR1 ameliorates LPS-induced pulmonary vascular endothelial cell injury by modulating miR-330-5p/TLR4 axis.
Yu Y, Sun H, Zhu L, Ji L, Liu H
Journal of biochemical and molecular toxicology 2021 Feb;35(2):e22644
Journal of biochemical and molecular toxicology 2021 Feb;35(2):e22644
NPM1 mutant maintains ULK1 protein stability via TRAF6-dependent ubiquitination to promote autophagic cell survival in leukemia.
Tang Y, Tao Y, Wang L, Yang L, Jing Y, Jiang X, Lei L, Yang Z, Wang X, Peng M, Xiao Q, Ren J, Zhang L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Feb;35(2):e21192
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Feb;35(2):e21192
Cell membrane-encapsulated magnetic nanoparticles for enhancing natural killer cell-mediated cancer immunotherapy.
Wu D, Shou X, Zhang Y, Li Z, Wu G, Wu D, Wu J, Shi S, Wang S
Nanomedicine : nanotechnology, biology, and medicine 2021 Feb;32:102333
Nanomedicine : nanotechnology, biology, and medicine 2021 Feb;32:102333
BML-111, the lipoxin A4 agonist, modulates VEGF or CoCl2-induced migration, angiogenesis and permeability in tumor-derived endothelial cells.
Lin L, Wang Q, Xu F, Luo X, Xu J, Yan L, Li Q, Hao H
Immunology letters 2021 Feb;230:27-35
Immunology letters 2021 Feb;230:27-35
MicroRNA‑338‑3p regulates age‑associated osteoporosis via targeting PCSK5.
Tong J, Zhang M, Li X, Ren G
Molecular medicine reports 2021 Feb;23(2)
Molecular medicine reports 2021 Feb;23(2)
Luteolin attenuates angiotensin II‑induced renal damage in apolipoprotein E‑deficient mice.
Liu YS, Yang Q, Li S, Luo L, Liu HY, Li XY, Gao ZN
Molecular medicine reports 2021 Feb;23(2)
Molecular medicine reports 2021 Feb;23(2)
Exercise reduces hyperlipidemia-induced kidney damage in apolipoprotein E-deficient mice.
Qian C, Yang Q, Guo L, Zhu H, You X, Liu H, Sun Y
Experimental and therapeutic medicine 2021 Feb;21(2):153
Experimental and therapeutic medicine 2021 Feb;21(2):153
F-Box protein 4 inhibits progression of papillary thyroid cancer.
Xu M, Wang Y, Chen M, Hu H, Xia T, Deng D
Steroids 2021 Feb;166:108773
Steroids 2021 Feb;166:108773
Novel clerodane-type diterpenoid Cintelactone A suppresses lipopolysaccharide -induced inflammation by promoting ubiquitination, proteasomal degradation of TRAF6.
Di Q, Zhao X, Zhang R, Ma X, Liang X, Li X, Gao J, Tang H, Chen W, Xiao W
Pharmacological research 2021 Feb;164:105386
Pharmacological research 2021 Feb;164:105386
Osteogenic differentiation and calcification of human aortic smooth muscle cells is induced by the RCN2/STAT3/miR-155-5p feedback loop.
Zhao J, Liu Z, Chang Z
Vascular pharmacology 2021 Feb;136:106821
Vascular pharmacology 2021 Feb;136:106821
Study on the protective effect and mechanism of Dicliptera chinensis (L.) Juss (Acanthaceae) polysaccharide on immune liver injury induced by LPS.
Xu Q, Xu J, Zhang K, Zhong M, Cao H, Wei R, Jin L, Gao Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Feb;134:111159
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Feb;134:111159
Impact of knockdown LincRNA-Cox2 on apoptosis of macrophage infected with Bacillus Calmette-Guérin.
Xu Y, Yu J, Ma C, Gong Z, Wu X, Deng G
Molecular immunology 2021 Feb;130:85-95
Molecular immunology 2021 Feb;130:85-95
Bach2 overexpression represses Th9 cell differentiation by suppressing IRF4 expression in systemic lupus erythematosus.
Sheng Y, Zhang J, Li K, Wang H, Wang W, Wen L, Gao J, Tang X, Tang H, Huang H, Cai M, Yuan T, Liu L, Zheng X, Zhu Z, Cui Y
FEBS open bio 2021 Feb;11(2):395-403
FEBS open bio 2021 Feb;11(2):395-403
Hypothermic oxygenated perfusion inhibits HECTD3-mediated TRAF3 polyubiquitination to alleviate DCD liver ischemia-reperfusion injury.
Zhou W, Zhong Z, Lin D, Liu Z, Zhang Q, Xia H, Peng S, Liu A, Lu Z, Wang Y, Ye S, Ye Q
Cell death & disease 2021 Feb 24;12(2):211
Cell death & disease 2021 Feb 24;12(2):211
An ESCRT-dependent step in fatty acid transfer from lipid droplets to mitochondria through VPS13D-TSG101 interactions.
Wang J, Fang N, Xiong J, Du Y, Cao Y, Ji WK
Nature communications 2021 Feb 23;12(1):1252
Nature communications 2021 Feb 23;12(1):1252
SEPHS1 promotes SMAD2/3/4 expression and hepatocellular carcinoma cells invasion.
Yang S, Zhang H, Yang H, Zhang J, Wang J, Luo T, Jiang Y, Hua H
Experimental hematology & oncology 2021 Feb 23;10(1):17
Experimental hematology & oncology 2021 Feb 23;10(1):17
Anti-NMDAR encephalitis induced in mice by active immunization with a peptide from the amino-terminal domain of the GluN1 subunit.
Ding Y, Zhou Z, Chen J, Peng Y, Wang H, Qiu W, Xie W, Zhang J, Wang H
Journal of neuroinflammation 2021 Feb 21;18(1):53
Journal of neuroinflammation 2021 Feb 21;18(1):53
Macrophage migration inhibitory factor activates the inflammatory response in joint capsule fibroblasts following post-traumatic joint contracture.
Zhang Y, Lu S, Fan S, Xu L, Jiang X, Wang K, Cai B
Aging 2021 Feb 17;13(4):5804-5823
Aging 2021 Feb 17;13(4):5804-5823
Rational design and synthesis of 6-aryl-6H-benzo[c]chromenes as non-steroidal progesterone receptor antagonists for use against cancers.
Qin J, Qu S, Zhu K, Cheng Y, Pan G, Jing W, Liu X, Sun X, Liu L
Bioorganic & medicinal chemistry 2021 Feb 15;32:116003
Bioorganic & medicinal chemistry 2021 Feb 15;32:116003
A genome-wide CRISPR screen identifies host factors that regulate SARS-CoV-2 entry.
Zhu Y, Feng F, Hu G, Wang Y, Yu Y, Zhu Y, Xu W, Cai X, Sun Z, Han W, Ye R, Qu D, Ding Q, Huang X, Chen H, Xu W, Xie Y, Cai Q, Yuan Z, Zhang R
Nature communications 2021 Feb 11;12(1):961
Nature communications 2021 Feb 11;12(1):961
Stabilizing mast cells improves acute lung injury after orthotopic liver transplantation via promotion of apoptosis in polymorphonuclear neutrophils.
Chen C, Zhang Z, Tan F, Meng F, Lai L, Chi X, Zhu Q
American journal of physiology. Lung cellular and molecular physiology 2021 Feb 1;320(2):L266-L275
American journal of physiology. Lung cellular and molecular physiology 2021 Feb 1;320(2):L266-L275
Prenylated xanthones from mangosteen (Garcinia mangostana) activate the AhR and Nrf2 pathways and protect intestinal barrier integrity in HT-29 cells.
Tocmo R, Le B, Heun A, van Pijkeren JP, Parkin K, Johnson JJ
Free radical biology & medicine 2021 Feb 1;163:102-115
Free radical biology & medicine 2021 Feb 1;163:102-115
ABIN-1 is a key regulator in RIPK1-dependent apoptosis (RDA) and necroptosis, and ABIN-1 deficiency potentiates necroptosis-based cancer therapy in colorectal cancer.
Cai J, Hu D, Sakya J, Sun T, Wang D, Wang L, Mao X, Su Z
Cell death & disease 2021 Feb 1;12(2):140
Cell death & disease 2021 Feb 1;12(2):140
Ataxia-telangiectasia mutated interacts with Parkin and induces mitophagy independent of kinase activity. Evidence from mantle cell lymphoma.
Sarkar A, Stellrecht CM, Vangapandu HV, Ayres M, Kaipparettu BA, Park JH, Balakrishnan K, Burks JK, Pandita TK, Hittelman WN, Neelapu SS, Gandhi V
Haematologica 2021 Feb 1;106(2):495-512
Haematologica 2021 Feb 1;106(2):495-512
Compound Kushen Injection intervenes metabolic reprogramming and epithelial-mesenchymal transition of HCC via regulating β-catenin/c-Myc signaling.
Wang KX, Du GH, Qin XM, Gao L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Dec;93:153781
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Dec;93:153781
Dendrobium nobile Lindl alkaloid attenuates 6-OHDA-induced dopamine neurotoxicity.
Li DD, Wang GQ, Wu Q, Shi JS, Zhang F
Biotechnology and applied biochemistry 2021 Dec;68(6):1501-1507
Biotechnology and applied biochemistry 2021 Dec;68(6):1501-1507
Simiao Qingwen Baidu decoction inhibits Epstein-Barr virus-induced B lymphoproliferative disease and lytic viral replication.
Yang X, Liu L, Zhang H, Sun X, Yan Y, Ran R
Pharmaceutical biology 2021 Dec;59(1):741-747
Pharmaceutical biology 2021 Dec;59(1):741-747
Chrysanthemi Flos extract alleviated acetaminophen-induced rat liver injury via inhibiting oxidative stress and apoptosis based on network pharmacology analysis.
Zhou Y, Wang C, Kou J, Wang M, Rong X, Pu X, Xie X, Han G, Pang X
Pharmaceutical biology 2021 Dec;59(1):1378-1387
Pharmaceutical biology 2021 Dec;59(1):1378-1387
Bone marrow macrophage-derived exosomal miR-143-5p contributes to insulin resistance in hepatocytes by repressing MKP5.
Li L, Zuo H, Huang X, Shen T, Tang W, Zhang X, An T, Dou L, Li J
Cell proliferation 2021 Dec;54(12):e13140
Cell proliferation 2021 Dec;54(12):e13140
Hsa_circ_0042823 accelerates cancer progression via miR-877-5p/FOXM1 axis in laryngeal squamous cell carcinoma.
Wu T, Sun Y, Sun Z, Li S, Wang W, Yu B, Wang G
Annals of medicine 2021 Dec;53(1):960-970
Annals of medicine 2021 Dec;53(1):960-970
Azathioprine pretreatment ameliorates myocardial ischaemia reperfusion injury in diabetic rats by reducing oxidative stress, apoptosis, and inflammation.
Lu C, Liu L, Chen S, Niu J, Li S, Xie W, Cheng X
Clinical and experimental pharmacology & physiology 2021 Dec;48(12):1621-1632
Clinical and experimental pharmacology & physiology 2021 Dec;48(12):1621-1632
Triptolide regulates oxidative stress and inflammation leading to hepatotoxicity via inducing CYP2E1.
Jiang HY, Bao YN, Lin FM, Jin Y
Human & experimental toxicology 2021 Dec;40(12_suppl):S775-S787
Human & experimental toxicology 2021 Dec;40(12_suppl):S775-S787
Non-canonical activation of the ER stress sensor ATF6 by Legionella pneumophila effectors.
Ibe NU, Subramanian A, Mukherjee S
Life science alliance 2021 Dec;4(12)
Life science alliance 2021 Dec;4(12)
Ramelteon Mitigates Free Fatty Acid (FFA)-Induced Attachment of Monocytes to Brain Vascular Endothelial Cells.
Wang G, Tian F, Li Y, Liu Y, Liu C
Neurotoxicity research 2021 Dec;39(6):1937-1945
Neurotoxicity research 2021 Dec;39(6):1937-1945
Acetabular development and fate of inverted limbus in rabbits: Experimental observation from an animal model.
Liu J, Zhou W, Chen Y, Li L
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2021 Dec;39(12):2595-2603
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2021 Dec;39(12):2595-2603
Bergenin alleviates H2 O2 -induced oxidative stress and apoptosis in nucleus pulposus cells: Involvement of the PPAR-γ/NF-κB pathway.
Zhang G, Wang H, Zhang Q, Zhao Z, Zhu W, Zuo X
Environmental toxicology 2021 Dec;36(12):2541-2550
Environmental toxicology 2021 Dec;36(12):2541-2550
ChREBP deficiency alleviates apoptosis by inhibiting TXNIP/oxidative stress in diabetic nephropathy.
Chen N, Song S, Yang Z, Wu M, Mu L, Zhou T, Shi Y
Journal of diabetes and its complications 2021 Dec;35(12):108050
Journal of diabetes and its complications 2021 Dec;35(12):108050
Low EGR1 expression predicts poor prognosis in clear cell renal cell carcinoma.
Zhang ZY, Zhang SL, Chen HL, Mao YQ, Kong CY, Li ZM, Wang LS, Ma M, Han B
Pathology, research and practice 2021 Dec;228:153666
Pathology, research and practice 2021 Dec;228:153666
TRIP4 transcriptionally activates DDIT4 and subsequent mTOR signaling to promote glioma progression.
Li W, Hu S, Tian C, Wan X, Yu W, Guo P, Zhao F, Hua C, Lu X, Xue G, Han S, Guo W, Wang D, Deng W
Free radical biology & medicine 2021 Dec;177:31-47
Free radical biology & medicine 2021 Dec;177:31-47
Pretreatment of Indobufen and Aspirin and their Combinations with Clopidogrel or Ticagrelor Alleviates Inflammasome Mediated Pyroptosis Via Inhibiting NF-κB/NLRP3 Pathway in Ischemic Stroke.
Li F, Xu D, Hou K, Gou X, Lv N, Fang W, Li Y
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2021 Dec;16(4):835-853
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2021 Dec;16(4):835-853
Empagliflozin protects diabetic pancreatic tissue from damage by inhibiting the activation of the NLRP3/caspase-1/GSDMD pathway in pancreatic β cells: in vitro and in vivo studies.
Liu P, Zhang Z, Wang J, Zhang X, Yu X, Li Y
Bioengineered 2021 Dec;12(2):9356-9366
Bioengineered 2021 Dec;12(2):9356-9366
The effects of Omarigliptin on promoting osteoblastic differentiation.
Liao F, Hu X, Chen R
Bioengineered 2021 Dec;12(2):11837-11846
Bioengineered 2021 Dec;12(2):11837-11846
High expression of transmembrane P24 trafficking protein 9 predicts poor prognosis in breast carcinoma.
Ju G, Xu C, Zeng K, Zhou T, Zang L
Bioengineered 2021 Dec;12(1):8965-8979
Bioengineered 2021 Dec;12(1):8965-8979
Silencing circular RNA circ_0054537 and upregulating microRNA-640 suppress malignant progression of renal cell carcinoma via regulating neuronal pentraxin-2 (NPTX2).
Pei L, Lv X, Jia G, Tan X, Li M, Zhang A
Bioengineered 2021 Dec;12(1):8279-8295
Bioengineered 2021 Dec;12(1):8279-8295
M2 Macrophage-derived exosomal miR-501 contributes to pubococcygeal muscle regeneration.
Zhou M, Li B, Liu C, Hu M, Tang J, Min J, Cheng J, Hong L
International immunopharmacology 2021 Dec;101(Pt B):108223
International immunopharmacology 2021 Dec;101(Pt B):108223
Biomimetic amphiphilic FAAP NPs nanoparticles: Synthesis, characterization and antivirus activity.
Li XH, Zhang Z, Ma X, Guo ZH, Ban X, Tian Z, Zhao L, Liu Q, He Q
International immunopharmacology 2021 Dec;101(Pt A):108047
International immunopharmacology 2021 Dec;101(Pt A):108047
Fyn kinase regulates dopaminergic neuronal apoptosis in animal and cell models of high glucose (HG) treatment.
Tan C, Liu X, Zhang X, Peng W, Wang H, Zhou W, Jiang J, Mo L, Chen Y, Chen L
BMC molecular and cell biology 2021 Dec 4;22(1):58
BMC molecular and cell biology 2021 Dec 4;22(1):58
Long non-coding RNA CRNDE exacerbates NPC advancement mediated by the miR-545-5p/CCND2 axis.
Ge S, Jiang C, Li M, Cheng Z, Feng X
Cancer cell international 2021 Dec 4;21(1):650
Cancer cell international 2021 Dec 4;21(1):650
Aureonitol Analogues and Orsellinic Acid Esters Isolated from Chaetomium elatum and Their Antineuroinflammatory Activity.
Ju F, Kuang QX, Li QZ, Huang LJ, Guo WX, Gong LQ, Dai YF, Wang L, Gu YC, Wang D, Deng Y, Guo DL
Journal of natural products 2021 Dec 24;84(12):3044-3054
Journal of natural products 2021 Dec 24;84(12):3044-3054
Calcium alleviates fluoride-induced kidney damage via FAS/FASL, TNFR/TNF, DR5/TRAIL pathways in rats.
Li H, Fan J, Zhao Y, Yang J, Xu H, Manthari RK, Cheng X, Wang J, Wang J
Ecotoxicology and environmental safety 2021 Dec 15;226:112851
Ecotoxicology and environmental safety 2021 Dec 15;226:112851
Circular RNA circEsyt2 regulates vascular smooth muscle cell remodeling via splicing regulation.
Gong X, Tian M, Cao N, Yang P, Xu Z, Zheng S, Liao Q, Chen C, Zeng C, Jose PA, Wang DZ, Jian Z, Xiao Y, Jiang DS, Wei X, Zhang B, Wang Y, Chen K, Wu G, Zeng C
The Journal of clinical investigation 2021 Dec 15;131(24)
The Journal of clinical investigation 2021 Dec 15;131(24)
Phosphatidylinositol 3,4,5-Trisphosphate-Dependent Rac Exchanger 2 Protein Facilitates Glioma Progression via Akt and Stat3 Signaling.
Shang J, Li Y, Yin G, Li Z, Jiang L, Bai Q
Journal of molecular neuroscience : MN 2021 Aug;71(8):1674-1682
Journal of molecular neuroscience : MN 2021 Aug;71(8):1674-1682
Guanosine and uridine alleviate airway inflammation via inhibition of the MAPK and NF-κB signals in OVA-induced asthmatic mice.
Luo Y, Chen H, Huang R, Wu Q, Li Y, He Y
Pulmonary pharmacology & therapeutics 2021 Aug;69:102049
Pulmonary pharmacology & therapeutics 2021 Aug;69:102049
Diosgenin Protects Against Kidney Injury and Mitochondrial Apoptosis Induced by 3-MCPD Through the Regulation of ER Stress, Ca2+ Homeostasis, and Bcl2 Expression.
Zhong Y, Jin C, Han J, Zhu J, Liu Q, Sun D, Xia X, Zhang Y, Peng X
Molecular nutrition & food research 2021 Aug;65(15):e2001202
Molecular nutrition & food research 2021 Aug;65(15):e2001202
Dental pulp stem cell-derived exosomes alleviate cerebral ischaemia-reperfusion injury through suppressing inflammatory response.
Li S, Luo L, He Y, Li R, Xiang Y, Xing Z, Li Y, Albashari AA, Liao X, Zhang K, Gao L, Ye Q
Cell proliferation 2021 Aug;54(8):e13093
Cell proliferation 2021 Aug;54(8):e13093
Hippocampal CA1 theta burst-induced LTP from weaning to adulthood: Cellular and molecular mechanisms in young male rats revisited.
Rodrigues NC, Silva-Cruz A, Caulino-Rocha A, Bento-Oliveira A, Alexandre Ribeiro J, Cunha-Reis D
The European journal of neuroscience 2021 Aug;54(4):5272-5292
The European journal of neuroscience 2021 Aug;54(4):5272-5292
Glutaredoxin 1 protects neurons from oxygen-glucose deprivation/reoxygenation (OGD/R)-induced apoptosis and oxidative stress via the modulation of GSK-3β/Nrf2 signaling.
Qiu Z, Li X, Duan C, Li R, Han L
Journal of bioenergetics and biomembranes 2021 Aug;53(4):369-379
Journal of bioenergetics and biomembranes 2021 Aug;53(4):369-379
MicroRNA-122 contributes to lipopolysaccharide-induced acute kidney injury via down-regulating the vitamin D receptor in the kidney.
He J, Du J, Yi B, Wang J, Zhang H, Li YC, Sun J
European journal of clinical investigation 2021 Aug;51(8):e13547
European journal of clinical investigation 2021 Aug;51(8):e13547
H2S Attenuates Sleep Deprivation-Induced Cognitive Impairment by Reducing Excessive Autophagy via Hippocampal Sirt-1 in WISTAR RATS.
Gao S, Tang YY, Jiang L, Lan F, Li X, Zhang P, Zou W, Chen YJ, Tang XQ
Neurochemical research 2021 Aug;46(8):1941-1952
Neurochemical research 2021 Aug;46(8):1941-1952
CQMUH-011 Inhibits LPS-Induced Microglia Activation and Ameliorates Brain Ischemic Injury in Mice.
Liu H, Hu X, Jiang R, Cai J, Lin Q, Fan Z, Zhao P, Wang S, Zou C, Du W, Dong Z, Liu Y
Inflammation 2021 Aug;44(4):1345-1358
Inflammation 2021 Aug;44(4):1345-1358
Quercetin hinders microglial activation to alleviate neurotoxicity via the interplay between NLRP3 inflammasome and mitophagy.
Han X, Xu T, Fang Q, Zhang H, Yue L, Hu G, Sun L
Redox biology 2021 Aug;44:102010
Redox biology 2021 Aug;44:102010
The p53/p21/p16 and PI3K/Akt signaling pathways are involved in the ameliorative effects of maltol on D-galactose-induced liver and kidney aging and injury.
Sha JY, Li JH, Zhou YD, Yang JY, Liu W, Jiang S, Wang YP, Zhang R, Di P, Li W
Phytotherapy research : PTR 2021 Aug;35(8):4411-4424
Phytotherapy research : PTR 2021 Aug;35(8):4411-4424
LncRNA-AC006129.1 reactivates a SOCS3-mediated anti-inflammatory response through DNA methylation-mediated CIC downregulation in schizophrenia.
Ni C, Jiang W, Wang Z, Wang Z, Zhang J, Zheng X, Liu Z, Ou H, Jiang T, Liang W, Wu F, Li Q, Hou Y, Yang Q, Guo B, Liu S, Li S, Li S, Yang E, Zhu XH, Huang X, Wen Z, Zhao C
Molecular psychiatry 2021 Aug;26(8):4511-4528
Molecular psychiatry 2021 Aug;26(8):4511-4528
The molecular mechanism underlying mitophagy-mediated hippocampal neuron apoptosis in diabetes-related depression.
Liu J, Liu L, Han YS, Yi J, Guo C, Zhao HQ, Ling J, Wang YH
Journal of cellular and molecular medicine 2021 Aug;25(15):7342-7353
Journal of cellular and molecular medicine 2021 Aug;25(15):7342-7353
Resveratrol affects the expression of uric acid transporter by improving inflammation.
Zhang X, Nie Q, Zhang Z, Zhao J, Zhang F, Wang C, Wang X, Song G
Molecular medicine reports 2021 Aug;24(2)
Molecular medicine reports 2021 Aug;24(2)
Aggravation of hepatic ischemia‑reperfusion injury with increased inflammatory cell infiltration is associated with the TGF‑β/Smad3 signaling pathway.
Li H, Shen X, Tong Y, Ji T, Feng Y, Tang Y, Mai R, Ye J, Que T, Luo X
Molecular medicine reports 2021 Aug;24(2)
Molecular medicine reports 2021 Aug;24(2)
miR-320a in serum exosomes promotes myocardial fibroblast proliferation via regulating the PIK3CA/Akt/mTOR signaling pathway in HEH2 cells.
Wang QG, Cheng BC, He YZ, Li LJ, Ling Y, Luo G, Wang L, Liang S, Zhang Y
Experimental and therapeutic medicine 2021 Aug;22(2):873
Experimental and therapeutic medicine 2021 Aug;22(2):873
Augmenter of liver regeneration ameliorates ischemia-reperfusion injury in steatotic liver via inhibition of the TLR4/NF-κB pathway.
Weng J, Wang X, Xu B, Li W
Experimental and therapeutic medicine 2021 Aug;22(2):863
Experimental and therapeutic medicine 2021 Aug;22(2):863
DNMT1-mediated PPARα methylation aggravates damage of retinal tissues in diabetic retinopathy mice.
Zhu Y, Wang X, Zhou X, Ding L, Liu D, Xu H
Biological research 2021 Aug 6;54(1):25
Biological research 2021 Aug 6;54(1):25
Ginsenoside Rg5 Improves Insulin Resistance and Mitochondrial Biogenesis of Liver via Regulation of the Sirt1/PGC-1α Signaling Pathway in db/db Mice.
Zhu Y, Yang H, Deng J, Fan D
Journal of agricultural and food chemistry 2021 Aug 4;69(30):8428-8439
Journal of agricultural and food chemistry 2021 Aug 4;69(30):8428-8439
YWHAZ interacts with DAAM1 to promote cell migration in breast cancer.
Mei J, Liu Y, Yu X, Hao L, Ma T, Zhan Q, Zhang Y, Zhu Y
Cell death discovery 2021 Aug 27;7(1):221
Cell death discovery 2021 Aug 27;7(1):221
Effects of RNA methylation N6-methyladenosine regulators on malignant progression and prognosis of melanoma.
Liu J, Zhou Z, Ma L, Li C, Lin Y, Yu T, Wei JF, Zhu L, Yao G
Cancer cell international 2021 Aug 26;21(1):453
Cancer cell international 2021 Aug 26;21(1):453
The Performance of HepG2 and HepaRG Systems through the Glass of Acetaminophen-Induced Toxicity.
Lőrincz T, Deák V, Makk-Merczel K, Varga D, Hajdinák P, Szarka A
Life (Basel, Switzerland) 2021 Aug 21;11(8)
Life (Basel, Switzerland) 2021 Aug 21;11(8)
Reactive microglia enhance the transmission of exosomal α-synuclein via toll-like receptor 2.
Xia Y, Zhang G, Kou L, Yin S, Han C, Hu J, Wan F, Sun Y, Wu J, Li Y, Huang J, Xiong N, Zhang Z, Wang T
Brain : a journal of neurology 2021 Aug 17;144(7):2024-2037
Brain : a journal of neurology 2021 Aug 17;144(7):2024-2037
Expression pattern and regulatory effect of lysine-specific demethylase 2A gene in clear cell renal cell carcinoma.
Wang J, Li T, Li X, Zhang Y, Wang X
BMC urology 2021 Aug 14;21(1):108
BMC urology 2021 Aug 14;21(1):108
Serum exosomal pregnancy zone protein as a promising biomarker in inflammatory bowel disease.
Shao J, Jin Y, Shao C, Fan H, Wang X, Yang G
Cellular & molecular biology letters 2021 Aug 10;26(1):36
Cellular & molecular biology letters 2021 Aug 10;26(1):36
CIHH protects the heart against left ventricular remodelling and myocardial fibrosis by balancing the renin-angiotensin system in SHR.
Yu B, Chen H, Guo XQ, Hua H, Guan Y, Cui F, Tian YM, Zhang HX, Zhang XJ, Zhang Y, Ma HJ
Life sciences 2021 Aug 1;278:119540
Life sciences 2021 Aug 1;278:119540
Virtual screening identified natural Keap1-Nrf2 PPI inhibitor alleviates inflammatory osteoporosis through Nrf2-mir214-Traf3 axis.
Hong J, Shi Z, Li C, Ji X, Li S, Chen Y, Jiang G, Shi M, Wang W, Zhang Y, Hu B, Yan S
Free radical biology & medicine 2021 Aug 1;171:365-378
Free radical biology & medicine 2021 Aug 1;171:365-378
Contribution of the NLRP3/IL-1β axis to impaired vasodilation in sepsis through facilitation of eNOS proteolysis and the protective role of melatonin.
Hu S, Pi Q, Luo M, Cheng Z, Liang X, Luo S, Xia Y
International immunopharmacology 2021 Apr;93:107388
International immunopharmacology 2021 Apr;93:107388
Autocrined leptin promotes proliferation of non-small cell lung cancer (NSCLC) via PI3K/AKT and p53 pathways.
Wang J, Zhou F, Li F, Wang B, Hu Y, Li X
Annals of translational medicine 2021 Apr;9(7):568
Annals of translational medicine 2021 Apr;9(7):568
Morusin inhibits the growth of human colorectal cancer HCT116‑derived sphere‑forming cells via the inactivation of Akt pathway.
Zhou Y, Li X, Ye M
International journal of molecular medicine 2021 Apr;47(4):1
International journal of molecular medicine 2021 Apr;47(4):1
MMP11 promotes the proliferation and progression of breast cancer through stabilizing Smad2 protein.
Zhuang Y, Li X, Zhan P, Pi G, Wen G
Oncology reports 2021 Apr;45(4)
Oncology reports 2021 Apr;45(4)
BOP1 Silencing Suppresses Gastric Cancer Proliferation through p53 Modulation.
Yang YP, Qin RH, Zhao JJ, Qin XY
Current medical science 2021 Apr;41(2):287-296
Current medical science 2021 Apr;41(2):287-296
Effect of luteinizing hormone concentration on transcriptome and subcellular organelle phenotype of ovarian granulosa cells.
Wan YT, Liu S, Zhao SK, Luo YY, Lv YS, Qu DN, Liu MH, Li Y
Journal of assisted reproduction and genetics 2021 Apr;38(4):809-824
Journal of assisted reproduction and genetics 2021 Apr;38(4):809-824
CRSP8 promotes thyroid cancer progression by antagonizing IKKα-induced cell differentiation.
Liao Y, Hua Y, Li Y, Zhang C, Yu W, Guo P, Zou K, Li W, Sun Y, Wang R, Zuo Y, Sui S, Tian C, Hao J, Chen M, Hu S, Chen M, Long Q, Wang X, Zou L, Xie F, Guo W, Deng W
Cell death and differentiation 2021 Apr;28(4):1347-1363
Cell death and differentiation 2021 Apr;28(4):1347-1363
Enhanced response to PD-L1 silencing by modulation of TME via balancing glucose metabolism and robust co-delivery of siRNA/Resveratrol with dual-responsive polyplexes.
Jia L, Gao Y, Zhou T, Zhao XL, Hu HY, Chen DW, Qiao MX
Biomaterials 2021 Apr;271:120711
Biomaterials 2021 Apr;271:120711
Zinc provides neuroprotection by regulating NLRP3 inflammasome through autophagy and ubiquitination in a spinal contusion injury model.
Lin JQ, Tian H, Zhao XG, Lin S, Li DY, Liu YY, Xu C, Mei XF
CNS neuroscience & therapeutics 2021 Apr;27(4):413-425
CNS neuroscience & therapeutics 2021 Apr;27(4):413-425
Honokiol induces paraptosis-like cell death of acute promyelocytic leukemia via mTOR & MAPK signaling pathways activation.
Liu X, Gu Y, Bian Y, Cai D, Li Y, Zhao Y, Zhang Z, Xue M, Zhang L
Apoptosis : an international journal on programmed cell death 2021 Apr;26(3-4):195-208
Apoptosis : an international journal on programmed cell death 2021 Apr;26(3-4):195-208
Oxymatrine reduces expression of programmed death-ligand 1 by promoting DNA demethylation in colorectal cancer cells.
Hua S, Gu M, Wang Y, Ban D, Ji H
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2021 Apr;23(4):750-756
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2021 Apr;23(4):750-756
Abnormal Glu/mGluR2/3/PI3K pathway in the hippocampal neurovascular unit leads to diabetes-related depression.
Liu J, Han YS, Liu L, Tang L, Yang H, Meng P, Zhao HQ, Wang YH
Neural regeneration research 2021 Apr;16(4):727-733
Neural regeneration research 2021 Apr;16(4):727-733
Involvement of NADPH oxidase in patulin-induced oxidative damage and cytotoxicity in HEK293 cells.
Han J, Jin C, Zhong Y, Zhu J, Liu Q, Sun D, Feng J, Xia X, Peng X
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Apr;150:112055
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Apr;150:112055
SPT6 recruits SND1 to co-activate human telomerase reverse transcriptase to promote colon cancer progression.
Diao C, Guo P, Yang W, Sun Y, Liao Y, Yan Y, Zhao A, Cai X, Hao J, Hu S, Yu W, Chen M, Wang R, Li W, Zuo Y, Pan J, Hua C, Lu X, Fan W, Zheng Z, Deng W, Luo G, Guo W
Molecular oncology 2021 Apr;15(4):1180-1202
Molecular oncology 2021 Apr;15(4):1180-1202
Change on apoptosis, autophagy and mitochondria of the Harderian gland in Cricetulus barabensis during age.
Kong XT, Wang Z, Mou JJ, Li CS, Xue HL, Wu M, Chen L, Xu JH, Xu LX
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 2021 Apr-May;253:110547
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 2021 Apr-May;253:110547
Downregulation of circular RNA circDOCK7 identified from diabetic rats after sleeve gastrectomy contributes to hepatocyte apoptosis through regulating miR-139-3p and MCM3.
Li L, Dong S, Li S, Xu Q, Wang S, Xiong Y, Cheng Y, Zhong M, Zhang G, Hu S
Biochemical and biophysical research communications 2021 Apr 9;548:134-142
Biochemical and biophysical research communications 2021 Apr 9;548:134-142
Smooth muscle-specific HuR knockout induces defective autophagy and atherosclerosis.
Liu S, Jiang X, Cui X, Wang J, Liu S, Li H, Yang J, Zhang C, Zhang W
Cell death & disease 2021 Apr 9;12(4):385
Cell death & disease 2021 Apr 9;12(4):385
GCG inhibits SARS-CoV-2 replication by disrupting the liquid phase condensation of its nucleocapsid protein.
Zhao M, Yu Y, Sun LM, Xing JQ, Li T, Zhu Y, Wang M, Yu Y, Xue W, Xia T, Cai H, Han QY, Yin X, Li WH, Li AL, Cui J, Yuan Z, Zhang R, Zhou T, Zhang XM, Li T
Nature communications 2021 Apr 9;12(1):2114
Nature communications 2021 Apr 9;12(1):2114
KLF5-mediated Eppk1 expression promotes cell proliferation in cervical cancer via the p38 signaling pathway.
Ma D, Pan Z, Chang Q, Zhang JJ, Liu X, Hua N, Li GH
BMC cancer 2021 Apr 8;21(1):377
BMC cancer 2021 Apr 8;21(1):377
Xanthine oxidase inhibitory activity and antihyperuricemic effect of Moringa oleifera Lam. leaf hydrolysate rich in phenolics and peptides.
Tian Y, Lin L, Zhao M, Peng A, Zhao K
Journal of ethnopharmacology 2021 Apr 24;270:113808
Journal of ethnopharmacology 2021 Apr 24;270:113808
cAMP-PKA signaling is involved in regulation of spinal HCN channels function in diabetic neuropathic pain.
Ma Y, Chen J, Yu D, Wei B, Jin H, Zeng J, Liu X
Neuroscience letters 2021 Apr 17;750:135763
Neuroscience letters 2021 Apr 17;750:135763
The SRSF1/circATP5B/miR-185-5p/HOXB5 feedback loop regulates the proliferation of glioma stem cells via the IL6-mediated JAK2/STAT3 signaling pathway.
Zhao J, Jiang Y, Zhang H, Zhou J, Chen L, Li H, Xu J, Zhang G, Jing Z
Journal of experimental & clinical cancer research : CR 2021 Apr 15;40(1):134
Journal of experimental & clinical cancer research : CR 2021 Apr 15;40(1):134
Spleen Tyrosine Kinase Mediates Microglial Activation in Mice With Diabetic Retinopathy.
Liu X, Xu B, Gao S
Translational vision science & technology 2021 Apr 1;10(4):20
Translational vision science & technology 2021 Apr 1;10(4):20
REG γ knockdown suppresses proliferation by inducing apoptosis and cell cycle arrest in osteosarcoma.
Yin Z, Jin H, Huang S, Qu G, Meng Q
PeerJ 2020;8:e8954
PeerJ 2020;8:e8954
Glutamate-Cysteine Ligase Catalytic Subunit Attenuated Hepatitis C Virus-Related Liver Fibrosis and Suppressed Endoplasmic Reticulum Stress.
Fu N, Li D, Li W, Zhao W, Zhang S, Liu L, Zhao S, Du J, Kong L, Wang R, Zhang Y, Nan Y
Frontiers in molecular biosciences 2020;7:199
Frontiers in molecular biosciences 2020;7:199
Promotion of cadmium uptake and cadmium-induced toxicity by the copper transporter CTR1 in HepG2 and ZFL cells.
Kwok ML, Li ZP, Law TYS, Chan KM
Toxicology reports 2020;7:1564-1570
Toxicology reports 2020;7:1564-1570
The Novel Synthetic Triterpene Methyl 3β-O-[4-(2-Aminoethylamino)-4-oxo-butyryl]olean-12-ene-28-oate Inhibits Breast Tumor Cell Growth in Vitro and in Vivo.
Feng B, Zhao C, Li J, Yu J, Zhang Y, Zhang X, Tian T, Zhao L
Chemical & pharmaceutical bulletin 2020;68(10):962-970
Chemical & pharmaceutical bulletin 2020;68(10):962-970
Baicalin Inhibits Coxsackievirus B3 Replication by Reducing Cellular Lipid Synthesis.
Wang MJ, Yang CH, Jin Y, Wan CB, Qian WH, Xing F, Li X, Liu YY
The American journal of Chinese medicine 2020;48(1):143-160
The American journal of Chinese medicine 2020;48(1):143-160
Anti-inflammation and anti-apoptosis effects of growth arrest-specific protein 6 in acute liver injury induced by LPS/D-GalN in mice.
Wang Q, Zhao Y, Zang B
Acta cirurgica brasileira 2020;35(2):e202000204
Acta cirurgica brasileira 2020;35(2):e202000204
Systematic investigation of biomarker-like role of ARHGDIB in breast cancer.
Wang X, Bi X, Huang X, Wang B, Guo Q, Wu Z
Cancer biomarkers : section A of Disease markers 2020;28(1):101-110
Cancer biomarkers : section A of Disease markers 2020;28(1):101-110
Xiao-Qing-Long-Tang Maintains Cardiac Function during Heart Failure with Reduced Ejection Fraction in Salt-Sensitive Rats by Regulating the Imbalance of Cardiac Sympathetic Innervation.
Li Z, Wang Y, Jiang Y, Ma D, Jiang P, Zhou G, Yang J, Dong F, Zhao H, Zhang Y, Li X
Evidence-based complementary and alternative medicine : eCAM 2020;2020:9467271
Evidence-based complementary and alternative medicine : eCAM 2020;2020:9467271
Phloretin Modulates Human Th17/Treg Cell Differentiation In Vitro via AMPK Signaling.
Jiao A, Yang Z, Fu X, Hua X
BioMed research international 2020;2020:6267924
BioMed research international 2020;2020:6267924
Role of Nrf2 in Lipopolysaccharide-Induced Acute Kidney Injury: Protection by Human Umbilical Cord Blood Mononuclear Cells.
Feng LX, Zhao F, Liu Q, Peng JC, Duan XJ, Yan P, Wu X, Wang HS, Deng YH, Duan SB
Oxidative medicine and cellular longevity 2020;2020:6123459
Oxidative medicine and cellular longevity 2020;2020:6123459
Heme Oxygenase-1 Suppresses Wnt Signaling Pathway in Nonalcoholic Steatohepatitis-Related Liver Fibrosis.
Du J, Ren W, Zhang Q, Fu N, Han F, Cui P, Li W, Kong L, Zhao S, Wang R, Zhang Y, Yang L, Kong L, Nan Y
BioMed research international 2020;2020:4910601
BioMed research international 2020;2020:4910601
Thymoquinone Protects against Hyperlipidemia-Induced Cardiac Damage in Low-Density Lipoprotein Receptor-Deficient (LDL-R-/-) Mice via Its Anti-inflammatory and Antipyroptotic Effects.
Pei ZW, Guo Y, Zhu HL, Dong M, Zhang Q, Wang F
BioMed research international 2020;2020:4878704
BioMed research international 2020;2020:4878704
Electroacupuncture Pretreatment Alleviates LPS-Induced Acute Respiratory Distress Syndrome via Regulating the PPAR Gamma/NF-Kappa B Signaling Pathway.
Feng D, Zhou H, Jin X, Wei J, Zhang Q, Gu Y, Zhang P, Yang H, Song J, Shi X, Lv X
Evidence-based complementary and alternative medicine : eCAM 2020;2020:4594631
Evidence-based complementary and alternative medicine : eCAM 2020;2020:4594631
Silencing ARAF Suppresses the Malignant Phenotypes of Gallbladder Cancer Cells.
Lin W, Tong C, Zhang W, Cen W, Wang Y, Li J, Zhu Z, Yu J, Lu B
BioMed research international 2020;2020:3235786
BioMed research international 2020;2020:3235786
Ellagic Acid Protects Dopamine Neurons via Inhibition of NLRP3 Inflammasome Activation in Microglia.
He XM, Zhou YZ, Sheng S, Li JJ, Wang GQ, Zhang F
Oxidative medicine and cellular longevity 2020;2020:2963540
Oxidative medicine and cellular longevity 2020;2020:2963540
miR-876 Inhibits EMT and Liver Fibrosis via POSTN to Suppress Metastasis in Hepatocellular Carcinoma.
Chen K, Li Z, Zhang M, Wang B, Peng T, Shen Y, Zhang J, Ye J, Liu Y, Tang D, Peng M, Ma D, Xiao Z, Zhang Y, Jin W, Li X
BioMed research international 2020;2020:1964219
BioMed research international 2020;2020:1964219
Anti-Inflammatory and Antioxidant Effect of Eucommia ulmoides Polysaccharide in Hepatic Ischemia-Reperfusion Injury by Regulating ROS and the TLR-4-NF-κB Pathway.
Gao W, Feng Z, Zhang S, Wu B, Geng X, Fan G, Duan Y, Li K, Liu K, Peng C
BioMed research international 2020;2020:1860637
BioMed research international 2020;2020:1860637
Effects of Hydrogen-rich Water on the PI3K/AKT Signaling Pathway in Rats with Myocardial Ischemia-reperfusion Injury.
Li L, Li X, Zhang Z, Liu L, Liu T, Li S, Liu S, Zhou Y, Liu F
Current molecular medicine 2020;20(5):396-406
Current molecular medicine 2020;20(5):396-406
A glycolysis-based 4-mRNA signature correlates with the prognosis and cell cycle process in patients with bladder cancer.
Zhang C, Gou X, He W, Yang H, Yin H
Cancer cell international 2020;20:177
Cancer cell international 2020;20:177
Structure-based discovery of neoandrographolide as a novel inhibitor of Rab5 to suppress cancer growth.
Zhang J, Sun Y, Zhong LY, Yu NN, Ouyang L, Fang RD, Wang Y, He QY
Computational and structural biotechnology journal 2020;18:3936-3946
Computational and structural biotechnology journal 2020;18:3936-3946
Nicotinamide Riboside Enhances Mitochondrial Proteostasis and Adult Neurogenesis through Activation of Mitochondrial Unfolded Protein Response Signaling in the Brain of ALS SOD1G93A Mice.
Zhou Q, Zhu L, Qiu W, Liu Y, Yang F, Chen W, Xu R
International journal of biological sciences 2020;16(2):284-297
International journal of biological sciences 2020;16(2):284-297
Methylglyoxal and D-lactate in cisplatin-induced acute kidney injury: Investigation of the potential mechanism via fluorogenic derivatization liquid chromatography-tandem mass spectrometry (FD-LC-MS/MS) proteomic analysis.
Chen SM, Chen TH, Chang HT, Lin TY, Lin CY, Tsai PY, Imai K, Chen CM, Lee JA
PloS one 2020;15(7):e0235849
PloS one 2020;15(7):e0235849
Interferon regulatory factor 7 mediates obesity-associated MCP-1 transcription.
Kuroda M, Nishiguchi M, Ugawa N, Ishikawa E, Kawabata Y, Okamoto S, Sasaki W, Miyatake Y, Sebe M, Masumoto S, Tsutsumi R, Harada N, Sakaue H
PloS one 2020;15(5):e0233390
PloS one 2020;15(5):e0233390
MicroRNA-9 mediated the protective effect of ferulic acid on hypoxic-ischemic brain damage in neonatal rats.
Yao K, Yang Q, Li Y, Lan T, Yu H, Yu Y
PloS one 2020;15(5):e0228825
PloS one 2020;15(5):e0228825
The effect of autophagy and mitochondrial fission on Harderian gland is greater than apoptosis in male hamsters during different photoperiods.
Xu JH, Wang Z, Mou JJ, Zhao XY, Geng XC, Wu M, Xue HL, Chen L, Xu LX
PloS one 2020;15(11):e0241561
PloS one 2020;15(11):e0241561
Utilizing methylglyoxal and D-lactate in urine to evaluate saikosaponin C treatment in mice with accelerated nephrotoxic serum nephritis.
Lin CY, Lee JA, Lin PY, Hua SC, Tsai PY, Chen BL, Lin CE, Lee TH, Chen SM
PloS one 2020;15(10):e0241053
PloS one 2020;15(10):e0241053
Effect of prednisolone on glyoxalase 1 in an inbred mouse model of aristolochic acid nephropathy using a proteomics method with fluorogenic derivatization-liquid chromatography-tandem mass spectrometry.
Chen SM, Lin CE, Chen HH, Cheng YF, Cheng HW, Imai K
PloS one 2020;15(1):e0227838
PloS one 2020;15(1):e0227838
Protective effects of essential oil from Fructus Alpiniae zerumbet on retinal Müller gliosis via the PPAR-γ-p-CREB signaling pathway.
Yang H, Gan S, Jiang Z, Song X, Chen T, Xu Y, Fu L, Zhang Y, Tao L, Shen X
Chinese medicine 2020;15:4
Chinese medicine 2020;15:4
MicroRNA 885-5p Inhibits Hepatocellular Carcinoma Metastasis by Repressing AEG1.
Li C, Wang X, Song Q
OncoTargets and therapy 2020;13:981-988
OncoTargets and therapy 2020;13:981-988
Bufalin Induces Glioma Cell Death by Apoptosis or Necroptosis.
LingHu HR, Luo H, Gang L
OncoTargets and therapy 2020;13:4767-4778
OncoTargets and therapy 2020;13:4767-4778
The Acetone Indigo Red Dehydrating Agent IF203 Induces HepG2 Cell Death Through Cell Cycle Arrest, Autophagy and Apoptosis.
Shang Y, Wang Q, Li J, Zhao Q, Huang X, Dong H, Liu H, Zhang Y, Zhang J, Gui R, Nie X
OncoTargets and therapy 2020;13:473-486
OncoTargets and therapy 2020;13:473-486
MicroRNA-375 Targets ATG14 to Inhibit Autophagy and Sensitize Hepatocellular Carcinoma Cells to Sorafenib.
Yang S, Wang M, Yang L, Li Y, Ma Y, Peng X, Li X, Li B, Jin H, Li H
OncoTargets and therapy 2020;13:3557-3570
OncoTargets and therapy 2020;13:3557-3570
Dihydroartemisinin Prevents Progression and Metastasis of Head and Neck Squamous Cell Carcinoma by Inhibiting Polarization of Macrophages in Tumor Microenvironment.
Chen R, Lu X, Li Z, Sun Y, He Z, Li X
OncoTargets and therapy 2020;13:3375-3387
OncoTargets and therapy 2020;13:3375-3387
Proteomics Analysis of Brain Tissue in a Rat Model of Ischemic Stroke in the Acute Phase.
Zheng F, Zhou YT, Zeng YF, Liu T, Yang ZY, Tang T, Luo JK, Wang Y
Frontiers in molecular neuroscience 2020;13:27
Frontiers in molecular neuroscience 2020;13:27
The Regulatory Mechanism and Biological Significance of Mitochondrial Calcium Uniporter in the Migration, Invasion, Angiogenesis and Growth of Gastric Cancer.
Wang X, Song X, Cheng G, Zhang J, Dong L, Bai J, Luo D, Xiong Y, Li S, Liu F, Sun Y, Wang X, Li Y, Huang Y
OncoTargets and therapy 2020;13:11781-11794
OncoTargets and therapy 2020;13:11781-11794
Melatonin ameliorates hyperglycaemia-induced renal inflammation by inhibiting the activation of TLR4 and TGF-β1/Smad3 signalling pathway.
Wei J, Wang Y, Qi X, Fan Z, Wu Y
American journal of translational research 2020;12(5):1584-1599
American journal of translational research 2020;12(5):1584-1599
Fenofibrate-induced mitochondrial dysfunction and metabolic reprogramming reversal: the anti-tumor effects in gastric carcinoma cells mediated by the PPAR pathway.
Chen L, Peng J, Wang Y, Jiang H, Wang W, Dai J, Tang M, Wei Y, Kuang H, Xu G, Xu H, Zhou F
American journal of translational research 2020;12(2):428-446
American journal of translational research 2020;12(2):428-446
Selaginellin B induces apoptosis and autophagy in pancreatic cancer cells via the JAK2/STAT3 signaling pathway.
Chu P, Wang S, Zhu X, Yang Y, Li H, Tesfaldet T, Shopit A, Yang Y, Ma X, Peng J, Tang Z, Sun Z
American journal of translational research 2020;12(11):7127-7143
American journal of translational research 2020;12(11):7127-7143
Identification of FADS1 Through Common Gene Expression Profiles for Predicting Survival in Patients with Bladder Cancer.
Jiao F, Sun H, Yang Q, Sun H, Wang Z, Liu M, Chen J
Cancer management and research 2020;12:8325-8339
Cancer management and research 2020;12:8325-8339
Blocking circ_0013912 Suppressed Cell Growth, Migration and Invasion of Pancreatic Ductal Adenocarcinoma Cells in vitro and in vivo Partially Through Sponging miR-7-5p.
Guo W, Zhao L, Wei G, Liu P, Zhang Y, Fu L
Cancer management and research 2020;12:7291-7303
Cancer management and research 2020;12:7291-7303
The Clinical Relevance and Function of Krüppel-Like Factor 16 in Breast Cancer.
Bang S, Li J, Zhang M, Cui R, Wu X, Xin Z, Ma D, Zhang J, Zhang H
Cancer management and research 2020;12:6373-6383
Cancer management and research 2020;12:6373-6383
The LINC00365/SCGB2A1 (Mammaglobin B) Axis Down-Regulates NF-κB Signaling and Is Associated with the Progression of Gastric Cancer.
Yan XY, Zhang JJ, Zhong XR, Yu SH, Xu L, Tian R, Sun LK, Su J
Cancer management and research 2020;12:621-631
Cancer management and research 2020;12:621-631
Inhibition of Skp2 Sensitizes Chronic Myeloid Leukemia Cells to Imatinib.
Chen X, Huang Z, Wu W, Xia R
Cancer management and research 2020;12:4777-4787
Cancer management and research 2020;12:4777-4787
LINC00963 Promotes Ovarian Cancer Proliferation, Migration and EMT via the miR-378g /CHI3L1 Axis.
Liu W, Yang YJ, An Q
Cancer management and research 2020;12:463-473
Cancer management and research 2020;12:463-473
Dl-3-n-Butylphthalide Promotes Remyelination and Suppresses Inflammation by Regulating AMPK/SIRT1 and STAT3/NF-κB Signaling in Chronic Cerebral Hypoperfusion.
Li M, Meng N, Guo X, Niu X, Zhao Z, Wang W, Xie X, Lv P
Frontiers in aging neuroscience 2020;12:137
Frontiers in aging neuroscience 2020;12:137
Hypoxia-induced MFAP5 Promotes Tumor Migration and Invasion via AKT Pathway in Head and Neck Squamous Cell Carcinoma.
Xu Q, Chang H, Tian X, Lou C, Ma H, Yang X
Journal of Cancer 2020;11(6):1596-1605
Journal of Cancer 2020;11(6):1596-1605
Weighted gene co-expression network analysis identifies CCNA2 as a treatment target of prostate cancer through inhibiting cell cycle.
Yang R, Du Y, Wang L, Chen Z, Liu X
Journal of Cancer 2020;11(5):1203-1211
Journal of Cancer 2020;11(5):1203-1211
miRNA-182 regulated MTSS1 inhibits proliferation and invasion in Glioma Cells.
Li Z, Zhang L, Liu Z, Huang T, Wang Y, Ma Y, Fang X, He Y, Zhou Y, Huo L, Wu J
Journal of Cancer 2020;11(19):5840-5851
Journal of Cancer 2020;11(19):5840-5851
Isoquercitrin Ameliorates Cisplatin-Induced Nephrotoxicity Via the Inhibition of Apoptosis, Inflammation, and Oxidative Stress.
Wang H, Xia W, Long G, Pei Z, Li Y, Wu M, Wang Q, Zhang Y, Jia Z, Chen H
Frontiers in pharmacology 2020;11:599416
Frontiers in pharmacology 2020;11:599416
Hydrogen Sulfide Attenuates High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease by Inhibiting Apoptosis and Promoting Autophagy via Reactive Oxygen Species/Phosphatidylinositol 3-Kinase/AKT/Mammalian Target of Rapamycin Signaling Pathway.
Wu D, Zhong P, Wang Y, Zhang Q, Li J, Liu Z, Ji A, Li Y
Frontiers in pharmacology 2020;11:585860
Frontiers in pharmacology 2020;11:585860
Integrated Analysis of Key Genes and Pathways Involved in Fetal Growth Restriction and Their Associations With the Dysregulation of the Maternal Immune System.
Wang X, Zhu H, Lei L, Zhang Y, Tang C, Wu JX, Zhou JR, Xiao XR
Frontiers in genetics 2020;11:581789
Frontiers in genetics 2020;11:581789
Mitochondrial DNA Haplogroup M7 Confers Disability in a Chinese Aging Population.
Sun D, Yao S, Wu F, Deng W, Ma Y, Jin L, Wang J, Wang X
Frontiers in genetics 2020;11:577795
Frontiers in genetics 2020;11:577795
The Human-Specific STING Agonist G10 Activates Type I Interferon and the NLRP3 Inflammasome in Porcine Cells.
Ming SL, Zeng L, Guo YK, Zhang S, Li GL, Ma YX, Zhai YY, Chang WR, Yang L, Wang J, Yang GY, Chu BB
Frontiers in immunology 2020;11:575818
Frontiers in immunology 2020;11:575818
Notoginsenoside R1 Protects Against the Acrylamide-Induced Neurotoxicity via Upregulating Trx-1-Mediated ITGAV Expression: Involvement of Autophagy.
Wang W, Huang L, Thomas ER, Hu Y, Zeng F, Li X
Frontiers in pharmacology 2020;11:559046
Frontiers in pharmacology 2020;11:559046
Fisetin Alleviated Bleomycin-Induced Pulmonary Fibrosis Partly by Rescuing Alveolar Epithelial Cells From Senescence.
Zhang L, Tong X, Huang J, Wu M, Zhang S, Wang D, Liu S, Fan H
Frontiers in pharmacology 2020;11:553690
Frontiers in pharmacology 2020;11:553690
Progesterone Regulates Glucose Metabolism Through Glucose Transporter 1 to Promote Endometrial Receptivity.
Zhang H, Qi J, Wang Y, Sun J, Li Z, Sui L, Fan J, Liu C, Shang Y, Kong L, Kong Y
Frontiers in physiology 2020;11:543148
Frontiers in physiology 2020;11:543148
Photoperiod Affects Harderian Gland Morphology and Secretion in Female Cricetulus barabensis: Autophagy, Apoptosis, and Mitochondria.
Wang Z, Xu JH, Mou JJ, Kong XT, Wu M, Xue HL, Xu LX
Frontiers in physiology 2020;11:408
Frontiers in physiology 2020;11:408
Characterization and Neuroprotection Potential of Seleno-Polymannuronate.
Bi D, Li X, Li T, Li X, Lin Z, Yao L, Li H, Xu H, Hu Z, Zhang Z, Liu Q, Xu X
Frontiers in pharmacology 2020;11:21
Frontiers in pharmacology 2020;11:21
Identification of Immune-Related Genes Contributing to the Development of Glioblastoma Using Weighted Gene Co-expression Network Analysis.
Kong Y, Feng ZC, Zhang YL, Liu XF, Ma Y, Zhao ZM, Huang B, Chen AJ, Zhang D, Thorsen F, Wang J, Yang N, Li XG
Frontiers in immunology 2020;11:1281
Frontiers in immunology 2020;11:1281
Liraglutide Ameliorates Erectile Dysfunction via Regulating Oxidative Stress, the RhoA/ROCK Pathway and Autophagy in Diabetes Mellitus.
Yuan P, Ma D, Gao X, Wang J, Li R, Liu Z, Wang T, Wang S, Liu J, Liu X
Frontiers in pharmacology 2020;11:1257
Frontiers in pharmacology 2020;11:1257
NNK-mediated upregulation of DEPDC1 stimulates the progression of oral squamous cell carcinoma by inhibiting CYP27B1 expression.
Guo J, Zhou S, Huang P, Xu S, Zhang G, He H, Zeng Y, Xu CX, Kim H, Tan Y
American journal of cancer research 2020;10(6):1745-1760
American journal of cancer research 2020;10(6):1745-1760
Novel ESCC-related gene ZNF750 as potential Prognostic biomarker and inhibits Epithelial-Mesenchymal Transition through directly depressing SNAI1 promoter in ESCC.
Kong P, Xu E, Bi Y, Xu X, Liu X, Song B, Zhang L, Cheng C, Yan T, Qian Y, Yang J, Ma Y, Cui H, Zhai Y, Zou B, Liu X, Cheng Y, Guo S, Cheng X, Cui Y
Theranostics 2020;10(4):1798-1813
Theranostics 2020;10(4):1798-1813
MicroRNA-590-3p inhibits invasion and metastasis in triple-negative breast cancer by targeting Slug.
Yan M, Ye L, Feng X, Shi R, Sun Z, Li Z, Liu T
American journal of cancer research 2020;10(3):965-974
American journal of cancer research 2020;10(3):965-974
An ultrasensitive hybridization chain reaction-amplified CRISPR-Cas12a aptasensor for extracellular vesicle surface protein quantification.
Xing S, Lu Z, Huang Q, Li H, Wang Y, Lai Y, He Y, Deng M, Liu W
Theranostics 2020;10(22):10262-10273
Theranostics 2020;10(22):10262-10273
Hsp90 inhibitor HSP990 in very low dose upregulates EAAT2 and exerts potent antiepileptic activity.
Sha L, Chen T, Deng Y, Du T, Ma K, Zhu W, Shen Y, Xu Q
Theranostics 2020;10(18):8415-8429
Theranostics 2020;10(18):8415-8429
LincRNA00494 Suppresses Non-small Cell Lung Cancer Cell Proliferation by Regulating SRCIN1 Expression as a ceRNA.
Dong J, Li B, Lin D, Lu D, Liu C, Lu X, Tang X, Li L, Zhu D, Liu J, Qiu X, Tian L, Zhou Q
Frontiers in oncology 2020;10:79
Frontiers in oncology 2020;10:79
Critical roles of microRNA-141-3p and CHD8 in hypoxia/reoxygenation-induced cardiomyocyte apoptosis.
Yao B, Wan X, Zheng X, Zhong T, Hu J, Zhou Y, Qin A, Ma Y, Yin D
Cell & bioscience 2020;10:20
Cell & bioscience 2020;10:20
Inhibition of formyl peptide receptor 1 activity suppresses tumorigenicity in vivo and attenuates the invasion and migration of lung adenocarcinoma cells under hypoxic conditions in vitro.
Huang B, Guo H, Ding J, Li J, Wang H, Xu J, Zheng Q, Zhou L, Dai Q
Annals of translational medicine 2020 Sep;8(18):1174
Annals of translational medicine 2020 Sep;8(18):1174
Effects of the linoleic acid/docosahexaenoic acid ratio and concentration inducing autophagy in Raw264.7 cells against Staphylococcus aureus.
Xu LY, Mu M, Wang ML, Liu JC, Zhou YJ, Wu J, Jiang BY, Chen MG, Hu D, Tao XR
Journal of clinical biochemistry and nutrition 2020 Sep;67(2):146-152
Journal of clinical biochemistry and nutrition 2020 Sep;67(2):146-152
Hyperbaric oxygen treatment mitigates liver damage in mice with noise exposure.
Meng X, Zhang X, Su Y, Gu Z, Xie X, Chang Y, Bao J
Clinical and experimental pharmacology & physiology 2020 Sep;47(9):1564-1574
Clinical and experimental pharmacology & physiology 2020 Sep;47(9):1564-1574
RIP1 promotes proliferation through G2/M checkpoint progression and mediates cisplatin-induced apoptosis and necroptosis in human ovarian cancer cells.
Zheng XL, Yang JJ, Wang YY, Li Q, Song YP, Su M, Li JK, Zhang L, Li ZP, Zhou B, Lin Y
Acta pharmacologica Sinica 2020 Sep;41(9):1223-1233
Acta pharmacologica Sinica 2020 Sep;41(9):1223-1233
Curcumin inhibits the growth of triple-negative breast cancer cells by silencing EZH2 and restoring DLC1 expression.
Zhou X, Jiao D, Dou M, Zhang W, Lv L, Chen J, Li L, Wang L, Han X
Journal of cellular and molecular medicine 2020 Sep;24(18):10648-10662
Journal of cellular and molecular medicine 2020 Sep;24(18):10648-10662
Cytisine attenuates bone loss of ovariectomy mouse by preventing RANKL-induced osteoclastogenesis.
Qian Z, Zhong Z, Ni S, Li D, Zhang F, Zhou Y, Kang Z, Qian J, Yu B
Journal of cellular and molecular medicine 2020 Sep;24(17):10112-10127
Journal of cellular and molecular medicine 2020 Sep;24(17):10112-10127
Pretreatment with the ALDH2 activator Alda‑1 protects rat livers from ischemia/reperfusion injury by inducing autophagy.
Liu Z, Ye S, Zhong X, Wang W, Lai CH, Yang W, Yue P, Luo J, Huang X, Zhong Z, Xiong Y, Fan X, Li L, Wang Y, Ye Q
Molecular medicine reports 2020 Sep;22(3):2373-2385
Molecular medicine reports 2020 Sep;22(3):2373-2385
Huoxuezhitong capsule ameliorates MIA-induced osteoarthritis of rats through suppressing PI3K/ Akt/ NF-κB pathway.
Ju L, Hu P, Chen P, Xue X, Li Z, He F, Qiu Z, Cheng J, Huang F
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Sep;129:110471
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Sep;129:110471
GALNT2 regulates ANGPTL3 cleavage in cells and in vivo of mice.
Li X, Zhang Y, Zhang M, Wang Y
Scientific reports 2020 Sep 30;10(1):16168
Scientific reports 2020 Sep 30;10(1):16168
RNA N6-methyladenosine reader IGF2BP3 regulates cell cycle and angiogenesis in colon cancer.
Yang Z, Wang T, Wu D, Min Z, Tan J, Yu B
Journal of experimental & clinical cancer research : CR 2020 Sep 29;39(1):203
Journal of experimental & clinical cancer research : CR 2020 Sep 29;39(1):203
Ability of Post-treatment Glycyrrhizic Acid to Mitigate Cerebral Ischemia/Reperfusion Injury in Diabetic Mice.
Li Y, Yao N, Zhang T, Guo F, Niu X, Wu Z, Hou S
Medical science monitor : international medical journal of experimental and clinical research 2020 Sep 28;26:e926551
Medical science monitor : international medical journal of experimental and clinical research 2020 Sep 28;26:e926551
4-Acetylantroquinonol B Inhibits Osteoclastogenesis by Inhibiting the Autophagy Pathway in a Simulated Microgravity Model.
Wu CH, Ou CH, Yen IC, Lee SY
International journal of molecular sciences 2020 Sep 22;21(18)
International journal of molecular sciences 2020 Sep 22;21(18)
WITHDRAWN: Resveratrol partially prevents learning and memory deficits in rats exposed to gaseous formaldehyde.
Niu H, Xie R, Li L, Zhang X, Wei X, Deng J, Li Z
Environmental toxicology and pharmacology 2020 Sep 22;
Environmental toxicology and pharmacology 2020 Sep 22;
Aberrant BMP2 Signaling in Patients Diagnosed with Osteoporosis.
Durbano HW, Halloran D, Nguyen J, Stone V, McTague S, Eskander M, Nohe A
International journal of molecular sciences 2020 Sep 21;21(18)
International journal of molecular sciences 2020 Sep 21;21(18)
MG53 Protects hUC-MSCs against Inflammatory Damage and Synergistically Enhances Their Efficacy in Neuroinflammation Injured Brain through Inhibiting NLRP3/Caspase-1/IL-1β Axis.
Ma S, Wang Y, Zhou X, Li Z, Zhang Z, Wang Y, Huang T, Zhang Y, Shi J, Guan F
ACS chemical neuroscience 2020 Sep 2;11(17):2590-2601
ACS chemical neuroscience 2020 Sep 2;11(17):2590-2601
NGF receptors and PI3K/AKT pathway involved in glucose fluctuation-induced damage to neurons and α-lipoic acid treatment.
Yan T, Zhang Z, Li D
BMC neuroscience 2020 Sep 17;21(1):38
BMC neuroscience 2020 Sep 17;21(1):38
MicroRNA-128-1-5p attenuates myocardial ischemia/reperfusion injury by suppressing Gadd45g-mediated apoptotic signaling.
Wan X, Yao B, Ma Y, Liu Y, Tang Y, Hu J, Li M, Fu S, Zheng X, Yin D
Biochemical and biophysical research communications 2020 Sep 10;530(1):314-321
Biochemical and biophysical research communications 2020 Sep 10;530(1):314-321
Amino Acids Regulate Cisplatin Insensitivity in Neuroblastoma.
Gunda V, Pathania AS, Chava S, Prathipati P, Chaturvedi NK, Coulter DW, Pandey MK, Durden DL, Challagundla KB
Cancers 2020 Sep 10;12(9)
Cancers 2020 Sep 10;12(9)
Clusterin contributes to hepatitis C virus-related hepatocellular carcinoma by regulating autophagy.
Fu N, Du H, Li D, Lu Y, Li W, Wang Y, Kong L, Du J, Zhao S, Ren W, Han F, Wang R, Zhang Y, Nan Y
Life sciences 2020 Sep 1;256:117911
Life sciences 2020 Sep 1;256:117911
Neuronostatin Promotion Soluble Aβ1-42 Oligomers: Induced Dysfunctional Brain Glucose Metabolism in Mice.
Yang S, Zhou F, Ma M, Yuan Y, Zhao S, Yu P
Neurochemical research 2020 Oct;45(10):2474-2486
Neurochemical research 2020 Oct;45(10):2474-2486
Inhibition of TBK1 by amlexanox attenuates paraquat-induced acute lung injury.
Wang N, Li Y, Wang X, Ma Z, Wang Y, Zhang C, Yuan Y, Zhao M
Toxicology 2020 Oct;443:152555
Toxicology 2020 Oct;443:152555
miR-21a in exosomes from Lewis lung carcinoma cells accelerates tumor growth through targeting PDCD4 to enhance expansion of myeloid-derived suppressor cells.
Zhang X, Li F, Tang Y, Ren Q, Xiao B, Wan Y, Jiang S
Oncogene 2020 Oct;39(40):6354-6369
Oncogene 2020 Oct;39(40):6354-6369
ROS-mediated PERK-eIF2α-ATF4 pathway plays an important role in arsenite-induced L-02 cells apoptosis via regulating CHOP-DR5 signaling.
Liu C, Zhang A
Environmental toxicology 2020 Oct;35(10):1100-1113
Environmental toxicology 2020 Oct;35(10):1100-1113
Protective effects of isorhamnetin on pulmonary arterial hypertension: in vivo and in vitro studies.
Chang Z, Wang JL, Jing ZC, Ma P, Xu QB, Na JR, Tian J, Ma X, Zhou W, Zhou R
Phytotherapy research : PTR 2020 Oct;34(10):2730-2744
Phytotherapy research : PTR 2020 Oct;34(10):2730-2744
Effect of autophagy on irradiation‑induced damage in osteoblast‑like MC3T3‑E1 cells.
Li R, Yang W, Hu X, Zhou D, Huang K, Wang C, Li Y, Liu B
Molecular medicine reports 2020 Oct;22(4):3473-3481
Molecular medicine reports 2020 Oct;22(4):3473-3481
STAT3-PTTG11 abrogation inhibits proliferation and induces apoptosis in malignant glioma cells.
Cui L, Xu L, Wang G, Wen J, Luo L, Zhao H, Chen S, Zheng M, Sun C, Jin X, Yang L
Oncology letters 2020 Oct;20(4):6
Oncology letters 2020 Oct;20(4):6
SLC25A10 performs an oncogenic role in human osteosarcoma.
Wang G, Xia J, Chen C, Qiu J, Sun P, Peng Z, Chen X, Xu B
Oncology letters 2020 Oct;20(4):2
Oncology letters 2020 Oct;20(4):2
Involvement of p53 Acetylation in Growth Suppression of Cutaneous T-Cell Lymphomas Induced by HDAC Inhibition.
Yu X, Li H, Zhu M, Hu P, Liu X, Qing Y, Wang X, Wang H, Wang Z, Xu J, Tan R, Guo Q, Hui H
The Journal of investigative dermatology 2020 Oct;140(10):2009-2022.e4
The Journal of investigative dermatology 2020 Oct;140(10):2009-2022.e4
DUSP5 (dual-specificity protein phosphatase 5) suppresses BCG-induced autophagy via ERK 1/2 signaling pathway.
Luo J, Xue D, Song F, Liu X, Li W, Wang Y
Molecular immunology 2020 Oct;126:101-109
Molecular immunology 2020 Oct;126:101-109
N-Ethyl-2-Pyrrolidinone-Substituted Flavan-3-Ols with Anti-inflammatory Activity in Lipopolysaccharide-Stimulated Macrophages Are Storage-Related Marker Compounds for Green Tea.
Dai W, Lou N, Xie D, Hu Z, Song H, Lu M, Shang D, Wu W, Peng J, Yin P, Lin Z
Journal of agricultural and food chemistry 2020 Oct 28;68(43):12164-12172
Journal of agricultural and food chemistry 2020 Oct 28;68(43):12164-12172
Regulatory coupling between long noncoding RNAs and senescence in irradiated microglia.
Xu A, Li R, Ren A, Jian H, Huang Z, Zeng Q, Wang B, Zheng J, Chen X, Zheng N, Zheng R, Tian Y, Liu M, Mao Z, Ji A, Yuan Y
Journal of neuroinflammation 2020 Oct 28;17(1):321
Journal of neuroinflammation 2020 Oct 28;17(1):321
Novel mechanisms underlying anti-polycystic ovary like syndrome effects of electroacupuncture in rats: suppressing SREBP1 to mitigate insulin resistance, mitochondrial dysfunction and oxidative stress.
Peng Y, Yang X, Luo X, Liu C, Cao X, Wang H, Guo L
Biological research 2020 Oct 27;53(1):50
Biological research 2020 Oct 27;53(1):50
Impaired mitochondrial medium-chain fatty acid oxidation drives periportal macrovesicular steatosis in sirtuin-5 knockout mice.
Goetzman ES, Bharathi SS, Zhang Y, Zhao XJ, Dobrowolski SF, Peasley K, Sims-Lucas S, Monga SP
Scientific reports 2020 Oct 27;10(1):18367
Scientific reports 2020 Oct 27;10(1):18367
HOTAIR maintains the stemness of ovarian cancer stem cells via the miR-206/TBX3 axis.
Zhang Y, Guo J, Cai E, Cai J, Wen Y, Lu S, Li X, Han Q, Jiang J, Li T, Wang Z
Experimental cell research 2020 Oct 15;395(2):112218
Experimental cell research 2020 Oct 15;395(2):112218
Hepatoprotective effects of Di Wu Yang Gan: A medicinal food against CCl4-induced hepatotoxicity in vivo and in vitro.
Xu W, Xiao M, Li J, Chen Y, Sun Q, Li H, Sun W
Food chemistry 2020 Oct 15;327:127093
Food chemistry 2020 Oct 15;327:127093
Nrf2 activation protects auditory hair cells from cisplatin-induced ototoxicity independent on mitochondrial ROS production.
Zhang W, Xiong H, Pang J, Su Z, Lai L, Lin H, Jian B, He W, Yang H, Zheng Y
Toxicology letters 2020 Oct 1;331:1-10
Toxicology letters 2020 Oct 1;331:1-10
Effect of Combined Sorafenib/Cisplatinum Treatment on the Autophagy and Proliferation of Hepatocellular Carcinoma hepG2 Cells in Vitro.
Wang Y, Wang L
Asian Pacific journal of cancer prevention : APJCP 2020 Oct 1;21(10):2853-2857
Asian Pacific journal of cancer prevention : APJCP 2020 Oct 1;21(10):2853-2857
Treatment with 5-methoxytryptophan attenuates microglia-induced neuroinflammation in spinal cord trauma.
Hong X, Jiang F, Li Y, Fang L, Qian Z, Chen H, Kong R
International immunopharmacology 2020 Nov;88:106988
International immunopharmacology 2020 Nov;88:106988
Echinacea polysaccharide alleviates LPS-induced lung injury via inhibiting inflammation, apoptosis and activation of the TLR4/NF-κB signal pathway.
Zhang H, Lang W, Wang S, Li B, Li G, Shi Q
International immunopharmacology 2020 Nov;88:106974
International immunopharmacology 2020 Nov;88:106974
Panax notoginseng saponin R1 modulates TNF-α/NF-κB signaling and attenuates allergic airway inflammation in asthma.
Xue K, Ruan L, Hu J, Fu Z, Tian D, Zou W
International immunopharmacology 2020 Nov;88:106860
International immunopharmacology 2020 Nov;88:106860
LMCD1 antisense RNA 1 (LMCD1-AS1) potentiates thyroid cancer cell growth and stemness via a positive feedback loop of LMCD1-AS1/miR-1287-5p/GLI2.
Shao J, Xu Y, Li H, Chen L, Wang W, Shen D, Chen J
Annals of translational medicine 2020 Nov;8(22):1508
Annals of translational medicine 2020 Nov;8(22):1508
PKCβ/NF-κB pathway in diabetic atrial remodeling.
Wang H, Xu Y, Xu A, Wang X, Cheng L, Lee S, Tse G, Li G, Liu T, Fu H
Journal of physiology and biochemistry 2020 Nov;76(4):637-653
Journal of physiology and biochemistry 2020 Nov;76(4):637-653
Induction of SPARC on Oxidative Stress, Inflammatory Phenotype Transformation, and Apoptosis of Human Brain Smooth Muscle Cells Via TGF-β1-NOX4 Pathway.
Tan X, Li T, Zhu S, Zhong W, Li F, Wang Y
Journal of molecular neuroscience : MN 2020 Nov;70(11):1728-1741
Journal of molecular neuroscience : MN 2020 Nov;70(11):1728-1741
MicroRNA-145 suppresses osteogenic differentiation of human jaw bone marrow mesenchymal stem cells partially via targeting semaphorin 3A.
Jin Y, Hong F, Bao Q, Xu Q, Duan R, Zhu Z, Zhang W, Ma C
Connective tissue research 2020 Nov;61(6):577-585
Connective tissue research 2020 Nov;61(6):577-585
HIF-1α ameliorates tubular injury in diabetic nephropathy via HO-1-mediated control of mitochondrial dynamics.
Jiang N, Zhao H, Han Y, Li L, Xiong S, Zeng L, Xiao Y, Wei L, Xiong X, Gao P, Yang M, Liu Y, Sun L
Cell proliferation 2020 Nov;53(11):e12909
Cell proliferation 2020 Nov;53(11):e12909
miR-124-3p increases in high glucose induced osteocyte-derived exosomes and regulates galectin-3 expression: A possible mechanism in bone remodeling alteration in diabetic periodontitis.
Li J, Guo Y, Chen YY, Liu Q, Chen Y, Tan L, Zhang SH, Gao ZR, Zhou YH, Zhang GY, Feng YZ
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Nov;34(11):14234-14249
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Nov;34(11):14234-14249
Pharmacological Effects of Fasudil on Flap Survival in a Rodent Model.
Ji E, Wang J, Wang L, Pan Z, Gao W
The Journal of surgical research 2020 Nov;255:575-582
The Journal of surgical research 2020 Nov;255:575-582
Exosomes derived from smooth muscle cells ameliorate diabetes-induced erectile dysfunction by inhibiting fibrosis and modulating the NO/cGMP pathway.
Song J, Sun T, Tang Z, Ruan Y, Liu K, Rao K, Lan R, Wang S, Wang T, Liu J
Journal of cellular and molecular medicine 2020 Nov;24(22):13289-13302
Journal of cellular and molecular medicine 2020 Nov;24(22):13289-13302
Endoplasmic reticulum stress remodels alveolar bone formation after tooth extraction.
Chen Y, Guo Y, Li J, Chen YY, Liu Q, Tan L, Gao ZR, Zhang SH, Zhou YH, Feng YZ
Journal of cellular and molecular medicine 2020 Nov;24(21):12411-12420
Journal of cellular and molecular medicine 2020 Nov;24(21):12411-12420
Downregulation of HDAC1 suppresses media degeneration by inhibiting the migration and phenotypic switch of aortic vascular smooth muscle cells in aortic dissection.
Sun L, Wang C, Yuan Y, Guo Z, He Y, Ma W, Zhang J
Journal of cellular physiology 2020 Nov;235(11):8747-8756
Journal of cellular physiology 2020 Nov;235(11):8747-8756
Insulin Promotes Corneal Nerve Repair and Wound Healing in Type 1 Diabetic Mice by Enhancing Wnt/β-Catenin Signaling.
Yang S, Zhang Y, Zhang Z, Dan J, Zhou Q, Wang X, Li W, Zhou L, Yang L, Xie L
The American journal of pathology 2020 Nov;190(11):2237-2250
The American journal of pathology 2020 Nov;190(11):2237-2250
Genkwadaphnin inhibits growth and invasion in hepatocellular carcinoma by blocking DHCR24-mediated cholesterol biosynthesis and lipid rafts formation.
Wu J, Guo L, Qiu X, Ren Y, Li F, Cui W, Song S
British journal of cancer 2020 Nov;123(11):1673-1685
British journal of cancer 2020 Nov;123(11):1673-1685
Deficiency of pseudogene UPAT leads to hepatocellular carcinoma progression and forms a positive feedback loop with ZEB1.
Xiang L, Huang X, Wang S, Ou H, Chen Z, Hu Z, Huang Y, Li X, Yuan Y, Yang D
Cancer science 2020 Nov;111(11):4102-4117
Cancer science 2020 Nov;111(11):4102-4117
miRNA-122-5p stimulates the proliferation and DNA synthesis and inhibits the early apoptosis of human spermatogonial stem cells by targeting CBL and competing with lncRNA CASC7.
Zhou F, Chen W, Cui Y, Liu B, Yuan Q, Li Z, He Z
Aging 2020 Nov 24;12(24):25528-25546
Aging 2020 Nov 24;12(24):25528-25546
Liver Expression of IGF2 and Related Proteins in ZBED6 Gene-Edited Pig by RNA-Seq.
Zhao H, Wu M, Liu S, Tang X, Yi X, Li Q, Wang S, Sun X
Animals : an open access journal from MDPI 2020 Nov 22;10(11)
Animals : an open access journal from MDPI 2020 Nov 22;10(11)
miR-100-3p inhibits the adipogenic differentiation of hMSCs by targeting PIK3R1 via the PI3K/AKT signaling pathway.
Wang T, Zhong D, Qin Z, He S, Gong Y, Li W, Li X
Aging 2020 Nov 20;12(24):25090-25100
Aging 2020 Nov 20;12(24):25090-25100
HMGB1 mediates homocysteine-induced endothelial cells pyroptosis via cathepsin V-dependent pathway.
Leng Y, Chen R, Chen R, He S, Shi X, Zhou X, Zhang Z, Chen AF
Biochemical and biophysical research communications 2020 Nov 19;532(4):640-646
Biochemical and biophysical research communications 2020 Nov 19;532(4):640-646
Polysaccharides from Armillariella tabescens mycelia ameliorate insulin resistance in type 2 diabetic mice.
Yang R, Li Y, Cai J, Ji J, Wang Y, Zhang W, Pan W, Chen Y
Food & function 2020 Nov 18;11(11):9675-9685
Food & function 2020 Nov 18;11(11):9675-9685
Vernonia patula (Dryand.) Merr. and Leucas chinensis (Retz.) R. Brown exert anti-inflammatory activities and relieve oxidative stress via Nrf2 activation.
Wu PS, Jeng J, Yang JJ, Kao V, Yen JH, Wu MJ
Journal of ethnopharmacology 2020 Nov 15;262:113155
Journal of ethnopharmacology 2020 Nov 15;262:113155
Lysine acetylation of F-actin decreases tropomyosin-based inhibition of actomyosin activity.
Schmidt W, Madan A, Foster DB, Cammarato A
The Journal of biological chemistry 2020 Nov 13;295(46):15527-15539
The Journal of biological chemistry 2020 Nov 13;295(46):15527-15539
Oral recombinant methioninase increases TRAIL receptor-2 expression to regress pancreatic cancer in combination with agonist tigatuzumab in an orthotopic mouse model.
Yamamoto J, Miyake K, Han Q, Tan Y, Inubushi S, Sugisawa N, Higuchi T, Tashiro Y, Nishino H, Homma Y, Matsuyama R, Chawla SP, Bouvet M, Singh SR, Endo I, Hoffman RM
Cancer letters 2020 Nov 1;492:174-184
Cancer letters 2020 Nov 1;492:174-184
Artesunate induces autophagy dependent apoptosis through upregulating ROS and activating AMPK-mTOR-ULK1 axis in human bladder cancer cells.
Zhou X, Chen Y, Wang F, Wu H, Zhang Y, Liu J, Cai Y, Huang S, He N, Hu Z, Jin X
Chemico-biological interactions 2020 Nov 1;331:109273
Chemico-biological interactions 2020 Nov 1;331:109273
Differential distribution and potential regulatory roles of estrogen receptor 2a and 2b in the pituitary of ricefield eel Monopterus albus.
Zheng Z, Liu M, Meng F, Zhang W, Zhang L
General and comparative endocrinology 2020 Nov 1;298:113554
General and comparative endocrinology 2020 Nov 1;298:113554
Norcantharidin protects against renal interstitial fibrosis by suppressing TWEAK-mediated Smad3 phosphorylation.
Zeng D, Xiao Z, Xu Q, Luo H, Wen L, Tang C, Shan Y, Tian J, Wei J, Li Y
Life sciences 2020 Nov 1;260:118488
Life sciences 2020 Nov 1;260:118488
The B7-H4 gene induces immune escape partly via upregulating the PD-1/Stat3 pathway in non-small cell lung cancer.
Yuan L, Ye J, Fan D
Human immunology 2020 May;81(5):254-261
Human immunology 2020 May;81(5):254-261
Protective effect of Berberine on reproductive function and spermatogenesis in diabetic rats via inhibition of ROS/JAK2/NFκB pathway.
Song J, Gao X, Tang Z, Li H, Ruan Y, Liu Z, Wang T, Wang S, Liu J, Jiang H
Andrology 2020 May;8(3):793-806
Andrology 2020 May;8(3):793-806
Cannabinoid receptor 2 activation alleviates septic lung injury by promoting autophagy via inhibition of inflammatory mediator release.
Liu AP, Yuan QH, Zhang B, Yang L, He QW, Chen K, Liu QS, Li Z, Zhan J
Cellular signalling 2020 May;69:109556
Cellular signalling 2020 May;69:109556
miR-362 knock-down promotes proliferation and inhibits apoptosis in porcine immature Sertoli cells by targeting the RMI1 gene.
Ran M, Luo H, Gao H, Tang X, Chen Y, Zeng X, Weng B, Chen B
Reproduction in domestic animals = Zuchthygiene 2020 May;55(5):547-558
Reproduction in domestic animals = Zuchthygiene 2020 May;55(5):547-558
miR‑95 promotes osteosarcoma growth by targeting SCNN1A.
Geng Y, Zhao S, Jia Y, Xia G, Li H, Fang Z, Zhang Q, Tian R
Oncology reports 2020 May;43(5):1429-1436
Oncology reports 2020 May;43(5):1429-1436
Establishment and characterization of an immortalized human chondrocyte cell line.
Yang J, Tang Y, Chen W, Zhang M, Hong F, Yang D, Bao Q, Yang Y, Jin Y, Li L, Ma C
Biotechnology letters 2020 May;42(5):707-716
Biotechnology letters 2020 May;42(5):707-716
Characterization of a Novel Interleukin-1 Receptor Antagonist from Sheep (Ovis aries).
Zhang SJ, Guo X, Hu P, Lu SY, Liu NN, Fu BQ, Wang N, Li YS, Wang LL, Chang J, Chang HZ, Liu ZS, Zhou Y, Ren HL
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2020 May;40(5):268-278
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2020 May;40(5):268-278
Relevance research between the expression of p16INK4a , Notch1, and hTERC genes: The development of HPV16-positive cervical cancer.
Huo W, Zhai S, Wang Y, Qiang X, Na R, Gui H, Wu N, Cao Y, Bai H
Journal of clinical laboratory analysis 2020 May;34(5):e23207
Journal of clinical laboratory analysis 2020 May;34(5):e23207
The role of PSMB5 in sodium arsenite-induced oxidative stress in L-02 cells.
Lv Y, Hu Q, Shi M, Wang W, Zheng Y, Yang Z, Peng L, Bi D, Zhang A, Hu Y
Cell stress & chaperones 2020 May;25(3):533-540
Cell stress & chaperones 2020 May;25(3):533-540
MiR-145-5p alleviates hypoxia/reoxygenation- induced cardiac microvascular endothelial cell injury in coronary heart disease by inhibiting Smad4 expression.
Li LL, Mao CD, Wang GP, Wang N, Xue AG
European review for medical and pharmacological sciences 2020 May;24(9):5008-5017
European review for medical and pharmacological sciences 2020 May;24(9):5008-5017
AMPK-mTOR-ULK1 axis activation-dependent autophagy promotes hydroxycamptothecin-induced apoptosis in human bladder cancer cells.
Wang F, Cao M, Fan M, Wu H, Huang W, Zhang Y, Hu Z, Jin X
Journal of cellular physiology 2020 May;235(5):4302-4315
Journal of cellular physiology 2020 May;235(5):4302-4315
Porcine parvovirus nonstructural protein NS1 activates NF-κB and it involves TLR2 signaling pathway.
Jin X, Yuan Y, Zhang C, Zhou Y, Song Y, Wei Z, Zhang G
Journal of veterinary science 2020 May;21(3):e50
Journal of veterinary science 2020 May;21(3):e50
Leptin mediates protection of hydrogen sulfide against 6-hydroxydopamine-induced Parkinson's disease: Involving enhancement in Warburg effect.
Yang SQ, Tian Q, Li D, He SQ, Hu M, Liu SY, Zou W, Chen YJ, Zhang P, Tang XQ
Neurochemistry international 2020 May;135:104692
Neurochemistry international 2020 May;135:104692
Expression and distribution of bone morphogenetic protein 4 and its antagonist Noggin in the skin of Kazakh sheep (Ovis aries) with a white and brown coat color.
Sun X, Qu G, Wang D, Wang T, Sai W, Chen Y, Yuan L, Pang Q
Acta histochemica 2020 May;122(4):151539
Acta histochemica 2020 May;122(4):151539
ROS enhances the cytotoxicity of cisplatin by inducing apoptosis and autophagy in tongue squamous cell carcinoma cells.
Xue DF, Pan ST, Huang G, Qiu JX
The international journal of biochemistry & cell biology 2020 May;122:105732
The international journal of biochemistry & cell biology 2020 May;122:105732
Regulation of epidermal differentiation through KDF1-mediated deubiquitination of IKKα.
Li Y, Tang L, Yue J, Gou X, Lin A, Weatherbee SD, Wu X
EMBO reports 2020 May 6;21(5):e48566
EMBO reports 2020 May 6;21(5):e48566
High glucose inhibits vascular endothelial Keap1/Nrf2/ARE signal pathway via downregulation of monomethyltransferase SET8 expression.
Chen X, Qi J, Wu Q, Jiang H, Wang J, Chen W, Mao A, Zhu M
Acta biochimica et biophysica Sinica 2020 May 26;52(5):506-516
Acta biochimica et biophysica Sinica 2020 May 26;52(5):506-516
Effects of inhalation of sevoflurane at different concentrations on TRPV1 in airways of rats at different developmental stages.
Liu D, Yuan J, Fei X, Zhu Y, Zhou Y, Zhang C, Dong L, Zhu Z
Life sciences 2020 May 15;249:117472
Life sciences 2020 May 15;249:117472
Inhibition of the NLRP3-inflammasome prevents cognitive deficits in experimental autoimmune encephalomyelitis mice via the alteration of astrocyte phenotype.
Hou B, Zhang Y, Liang P, He Y, Peng B, Liu W, Han S, Yin J, He X
Cell death & disease 2020 May 15;11(5):377
Cell death & disease 2020 May 15;11(5):377
LncRNA TROJAN promotes proliferation and resistance to CDK4/6 inhibitor via CDK2 transcriptional activation in ER+ breast cancer.
Jin X, Ge LP, Li DQ, Shao ZM, Di GH, Xu XE, Jiang YZ
Molecular cancer 2020 May 11;19(1):87
Molecular cancer 2020 May 11;19(1):87
Overexpression of endogenous lipoic acid synthase attenuates pulmonary fibrosis induced by crystalline silica in mice.
Zhao Y, Xu G, Li H, Chang M, Guan Y, Li Y, Wu W, Yao S
Toxicology letters 2020 May 1;323:57-66
Toxicology letters 2020 May 1;323:57-66
Association analysis of DNA methyltransferases in IgA nephropathy.
Xia M, Chen G, Liu D, Tang X, Liu Y, Wu L, Liu Y, Liu H
International immunopharmacology 2020 Mar;80:106147
International immunopharmacology 2020 Mar;80:106147
Role of PEPT1in the transport of cinnabar in Caco-2 cells.
Wu Q, He X, Zhou S, Shi F, Lu Y
Toxicology in vitro : an international journal published in association with BIBRA 2020 Mar;63:104747
Toxicology in vitro : an international journal published in association with BIBRA 2020 Mar;63:104747
MTFP1 overexpression promotes the growth of oral squamous cell carcinoma by inducing ROS production.
Xiao T, Sun J, Xing Z, Xie F, Yang L, Ding W
Cell biology international 2020 Mar;44(3):821-829
Cell biology international 2020 Mar;44(3):821-829
Soluble Uric Acid Promotes Atherosclerosis via AMPK (AMP-Activated Protein Kinase)-Mediated Inflammation.
Kimura Y, Yanagida T, Onda A, Tsukui D, Hosoyamada M, Kono H
Arteriosclerosis, thrombosis, and vascular biology 2020 Mar;40(3):570-582
Arteriosclerosis, thrombosis, and vascular biology 2020 Mar;40(3):570-582
Sodium butyrate inhibits migration and induces AMPK-mTOR pathway-dependent autophagy and ROS-mediated apoptosis via the miR-139-5p/Bmi-1 axis in human bladder cancer cells.
Wang F, Wu H, Fan M, Yu R, Zhang Y, Liu J, Zhou X, Cai Y, Huang S, Hu Z, Jin X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):4266-4282
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):4266-4282
Guizhi Decoction () Inhibits Cholinergic Transdifferentiation by Regulating Imbalance of NGF and LIF in Salt-Sensitive Hypertensive Heart Failure Rats.
Wang YC, Ma DF, Jiang P, Zhang YM, Zhou GF, Yang JL, Li ZY, Li X
Chinese journal of integrative medicine 2020 Mar;26(3):188-196
Chinese journal of integrative medicine 2020 Mar;26(3):188-196
Hyperthermic intraperitoneal chemotherapy with recombinant mutant human TNF-α and raltitrexed in mice with colorectal-peritoneal carcinomatosis.
Gong Q, Song C, Wang X, Wang R, Cai G, Liang X, Liu J
Experimental biology and medicine (Maywood, N.J.) 2020 Mar;245(6):542-551
Experimental biology and medicine (Maywood, N.J.) 2020 Mar;245(6):542-551
Prenatal hypoxia inhibited propionate-evoked BK channels of mesenteric artery smooth muscle cells in offspring.
Zhang W, Feng X, Zhang Y, Sun M, Li L, Gao Q, Tang J, Zhang P, Lv J, Zhou X, Xu Z
Journal of cellular and molecular medicine 2020 Mar;24(5):3192-3202
Journal of cellular and molecular medicine 2020 Mar;24(5):3192-3202
LncRNA MALAT1 knockdown inhibits cell migration and invasion by suppressing autophagy through miR-384/GOLM1 axis in glioma.
Ma R, Zhang BW, Zhang ZB, Deng QJ
European review for medical and pharmacological sciences 2020 Mar;24(5):2601-2615
European review for medical and pharmacological sciences 2020 Mar;24(5):2601-2615
The Immunomodulatory Effects and Mechanisms of Tim-3 Action in the Early Stage of Mice with Severe Acute Pancreatitis.
Lin M, Huang J, Chen WC, Fan ZN, Qin X
Iranian journal of immunology : IJI 2020 Mar;17(1):52-63
Iranian journal of immunology : IJI 2020 Mar;17(1):52-63
Protein microarray analysis of cytokine expression changes in distal stumps after sciatic nerve transection.
Cheng XQ, Liang XZ, Wei S, Ding X, Han GH, Liu P, Sun X, Quan Q, Tang H, Zhao Q, Shang AJ, Peng J
Neural regeneration research 2020 Mar;15(3):503-511
Neural regeneration research 2020 Mar;15(3):503-511
CADM1 inhibits ovarian cancer cell proliferation and migration by potentially regulating the PI3K/Akt/mTOR pathway.
Si X, Xu F, Xu F, Wei M, Ge Y, Chenge S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Mar;123:109717
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Mar;123:109717
Metformin alleviates breast cancer through targeting high-mobility group AT-hook 2.
Li Y, Wang D, Ren H, Feng W
Thoracic cancer 2020 Mar;11(3):686-692
Thoracic cancer 2020 Mar;11(3):686-692
circFOXM1 promotes proliferation of non-small cell lung carcinoma cells by acting as a ceRNA to upregulate FAM83D.
Yu C, Cheng Z, Cui S, Mao X, Li B, Fu Y, Wang H, Jin H, Ye Q, Zhao X, Jiang L, Qin W
Journal of experimental & clinical cancer research : CR 2020 Mar 30;39(1):55
Journal of experimental & clinical cancer research : CR 2020 Mar 30;39(1):55
Anti-neuroinflammatory effect of 3,4-dihydroxybenzaldehyde in ischemic stroke.
Li X, Xiang B, Shen T, Xiao C, Dai R, He F, Lin Q
International immunopharmacology 2020 Mar 3;82:106353
International immunopharmacology 2020 Mar 3;82:106353
Role of autophagy and apoptosis in atrophic epithelium in oral submucous fibrosis.
Zhu B, Jiang Q, Que G, Dai Z, Wu Y
Journal of oral science 2020 Mar 28;62(2):184-188
Journal of oral science 2020 Mar 28;62(2):184-188
The mechanism and role of intracellular α-ketoglutarate reduction in hepatic stellate cell activation.
Zhao J, Jiang Y, Sun X, Liu X, Liu F, Song M, Zhang L
Bioscience reports 2020 Mar 27;40(3)
Bioscience reports 2020 Mar 27;40(3)
Connective tissue growth factor as an unfavorable prognostic marker promotes the proliferation, migration, and invasion of gliomas.
Song ZB, Yang HP, Xu AQ, Zhan ZM, Song Y, Li ZY
Chinese medical journal 2020 Mar 20;(6):670-678
Chinese medical journal 2020 Mar 20;(6):670-678
The Late Domain of Prototype Foamy Virus Gag Facilitates Autophagic Clearance of Stress Granules by Promoting Amphisome Formation.
Zheng Y, Zhu G, Yan J, Tang Y, Han S, Yin J, Peng B, He X, Liu W
Journal of virology 2020 Mar 17;94(7)
Journal of virology 2020 Mar 17;94(7)
Critical role of toll-like receptor 4 (TLR4) in ricin toxin-induced inflammatory responses in macrophages.
Dong M, Yu H, Wang Y, Sun C, Chang Y, Yin Q, Zhao G, Xu N, Liu W
Toxicology letters 2020 Mar 15;321:54-60
Toxicology letters 2020 Mar 15;321:54-60
Monocyte-derived extracellular vesicles upon treated by palmitate promote endothelial migration and monocytes attachment to endothelial cells.
Gao W, Guo X, Wang Y, Jian D, Li M
Biochemical and biophysical research communications 2020 Mar 12;523(3):685-691
Biochemical and biophysical research communications 2020 Mar 12;523(3):685-691
Transgelin-2 contributes to proliferation and progression of hepatocellular carcinoma via regulating Annexin A2.
Shi J, Ren M, She X, Zhang Z, Zhao Y, Han Y, Lu D, Lyu L
Biochemical and biophysical research communications 2020 Mar 12;523(3):632-638
Biochemical and biophysical research communications 2020 Mar 12;523(3):632-638
Effect of NF-κB signal pathway on mucus secretion induced by atmospheric PM2.5 in asthmatic rats.
Liu Y, Zhang B, Zhang T, Wang H, Peng L, Zhou L
Ecotoxicology and environmental safety 2020 Mar 1;190:110094
Ecotoxicology and environmental safety 2020 Mar 1;190:110094
Club cell 10-kDa protein (CC10) inhibits cPLA2/COX2 pathway to alleviate RSV-induced airway inflammation and AHR.
Yu G, Mo S, Gao L, Wen X, Chen S, Long X, Xie X, Deng Y, Ren L, Zang N, Chen S, Liu E
International immunopharmacology 2020 Jun;83:106327
International immunopharmacology 2020 Jun;83:106327
Microglia polarization of hippocampus is involved in the mechanism of Apelin-13 ameliorating chronic water immersion restraint stress-induced depression-like behavior in rats.
Zhou S, Chen S, Xie W, Guo X, Zhao J
Neuropeptides 2020 Jun;81:102006
Neuropeptides 2020 Jun;81:102006
Dihydromethysticin, a natural molecule from Kava, suppresses the growth of colorectal cancer via the NLRC3/PI3K pathway.
Pan H, Liu F, Wang J, Zhao M, Wang D, Jia C, Wang T, Chen Z, Fan Y, Liang D, Meng Q
Molecular carcinogenesis 2020 Jun;59(6):575-589
Molecular carcinogenesis 2020 Jun;59(6):575-589
Obesity induces preadipocyte CD36 expression promoting inflammation via the disruption of lysosomal calcium homeostasis and lysosome function.
Luo X, Li Y, Yang P, Chen Y, Wei L, Yu T, Xia J, Ruan XZ, Zhao L, Chen Y
EBioMedicine 2020 Jun;56:102797
EBioMedicine 2020 Jun;56:102797
Effects of cisplatin on the proliferation, invasion and apoptosis of breast cancer cells following β‑catenin silencing.
Zhu X, Feng J, Fu W, Shu X, Wan X, Liu J
International journal of molecular medicine 2020 Jun;45(6):1838-1850
International journal of molecular medicine 2020 Jun;45(6):1838-1850
Compositional characterization of Pyrus ussuriensis Maxim and their antioxidant activities and induction of apoptosis in Bel-7402 cell.
Peng F, Li G, Xie Y, Yin HY, Li XJ, Yang YD
Journal of food biochemistry 2020 Jun;44(6):e13222
Journal of food biochemistry 2020 Jun;44(6):e13222
Alda-1, an Aldehyde Dehydrogenase 2 Agonist, Improves Cutaneous Wound Healing by Activating Epidermal Keratinocytes via Akt/GSK-3β/β-Catenin Pathway.
Zhang S, Chen C, Ying J, Wei C, Wang L, Yang Z, Qi F
Aesthetic plastic surgery 2020 Jun;44(3):993-1005
Aesthetic plastic surgery 2020 Jun;44(3):993-1005
Protein Phosphatase 2A Inhibiting β-Catenin Phosphorylation Contributes Critically to the Anti-renal Interstitial Fibrotic Effect of Norcantharidin.
Xiao Z, Wen L, Zeng D, Yin D, Zhou X, Tang C, Li Y
Inflammation 2020 Jun;43(3):878-891
Inflammation 2020 Jun;43(3):878-891
Neuroprotective effects of notoginsenoside R1 by upregulating Trx-1 on acrylamide-induced neurotoxicity in PC12.
Wang W, Huang L, Hu Y, Thomas ER, Li X
Human & experimental toxicology 2020 Jun;39(6):797-807
Human & experimental toxicology 2020 Jun;39(6):797-807
Hispidulin Inhibits Neuroinflammation in Lipopolysaccharide-Activated BV2 Microglia and Attenuates the Activation of Akt, NF-κB, and STAT3 Pathway.
Yu CI, Cheng CI, Kang YF, Chang PC, Lin IP, Kuo YH, Jhou AJ, Lin MY, Chen CY, Lee CH
Neurotoxicity research 2020 Jun;38(1):163-174
Neurotoxicity research 2020 Jun;38(1):163-174
CAFs-derived MFAP5 promotes bladder cancer malignant behavior through NOTCH2/HEY1 signaling.
Zhou Z, Cui D, Sun MH, Huang JL, Deng Z, Han BM, Sun XW, Xia SJ, Sun F, Shi F
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jun;34(6):7970-7988
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jun;34(6):7970-7988
Effect of STAT3 mediated epigenetic regulation in pre-eclampsia: an analysis of trial data.
Zhang XL, Pan J, Wang G, Li H, Wang JL, Jiang XM, Zhao XY
European review for medical and pharmacological sciences 2020 Jun;24(11):5843-5855
European review for medical and pharmacological sciences 2020 Jun;24(11):5843-5855
Triiodothyronine potentiates angiogenesis-related factor expression through PI3K/AKT signaling pathway in human osteoarthritic osteoblasts.
Li L, Pang Y, Zhang L, Li M, Zhu C, Fang S, Yin Z
Iranian journal of basic medical sciences 2020 Jun;23(6):819-825
Iranian journal of basic medical sciences 2020 Jun;23(6):819-825
Correction of Bcl-x splicing improves responses to imatinib in chronic myeloid leukaemia cells and mouse models.
Zhang J, Wang Y, Li SQ, Fang L, Wang XZ, Li J, Zhang HB, Huang B, Xu YM, Yang WM, Lin J, Min QH, Liao ZH, Wu Y, Liu J
British journal of haematology 2020 Jun;189(6):1141-1150
British journal of haematology 2020 Jun;189(6):1141-1150
Tubeimoside I improves survival of mice in sepsis by inhibiting inducible nitric oxide synthase expression.
Luo M, Luo S, Cheng Z, Yang X, Lv D, Li X, Guo Y, Li C, Yan J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jun;126:110083
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jun;126:110083
CD4+ T cells and TGFβ1/MAPK signal pathway involved in the valvular hyperblastosis and fibrosis in patients with rheumatic heart disease.
Zhao Z, He D, Ling F, Chu T, Huang D, Wu H, Ge J
Experimental and molecular pathology 2020 Jun;114:104402
Experimental and molecular pathology 2020 Jun;114:104402
Beneficial Effects of Theta-Burst Transcranial Magnetic Stimulation on Stroke Injury via Improving Neuronal Microenvironment and Mitochondrial Integrity.
Zong X, Dong Y, Li Y, Yang L, Li Y, Yang B, Tucker L, Zhao N, Brann DW, Yan X, Hu S, Zhang Q
Translational stroke research 2020 Jun;11(3):450-467
Translational stroke research 2020 Jun;11(3):450-467
Pseudolaric acid B induces mitotic arrest and apoptosis in both imatinib-sensitive and -resistant chronic myeloid leukaemia cells.
Jiang L, Wen C, He Q, Sun Y, Wang J, Lan X, Rohondia S, Dou QP, Shi X, Liu J
European journal of pharmacology 2020 Jun 5;876:173064
European journal of pharmacology 2020 Jun 5;876:173064
lncRNA MIRF Promotes Cardiac Apoptosis through the miR-26a-Bak1 Axis.
Su X, Lv L, Li Y, Fang R, Yang R, Li C, Li T, Zhu D, Li X, Zhou Y, Shan H, Liang H
Molecular therapy. Nucleic acids 2020 Jun 5;20:841-850
Molecular therapy. Nucleic acids 2020 Jun 5;20:841-850
Paeoniflorin-6'-O-benzene sulfonate down-regulates CXCR4-Gβγ-PI3K/AKT mediated migration in fibroblast-like synoviocytes of rheumatoid arthritis by inhibiting GRK2 translocation.
Wang DD, Jiang MY, Wang W, Zhou WJ, Zhang YW, Yang M, Chen JY, Wei W
Biochemical and biophysical research communications 2020 Jun 4;526(3):805-812
Biochemical and biophysical research communications 2020 Jun 4;526(3):805-812
Deletion of the Impg2 gene causes the degeneration of rod and cone cells in mice.
Xu H, Qu C, Gan L, Sun K, Tan J, Liu X, Jiang Z, Tian W, Liu W, Zhang S, Yang Y, Jiang L, Zhu X, Zhang L
Human molecular genetics 2020 Jun 27;29(10):1624-1634
Human molecular genetics 2020 Jun 27;29(10):1624-1634
The RBP1-CKAP4 axis activates oncogenic autophagy and promotes cancer progression in oral squamous cell carcinoma.
Gao L, Wang Q, Ren W, Zheng J, Li S, Dou Z, Kong X, Liang X, Zhi K
Cell death & disease 2020 Jun 25;11(6):488
Cell death & disease 2020 Jun 25;11(6):488
A Gold(I) Complex Containing an Oleanolic Acid Derivative as a Potential Anti-Ovarian-Cancer Agent by Inhibiting TrxR and Activating ROS-Mediated ERS.
Bian M, Sun Y, Liu Y, Xu Z, Fan R, Liu Z, Liu W
Chemistry (Weinheim an der Bergstrasse, Germany) 2020 Jun 2;26(31):7092-7108
Chemistry (Weinheim an der Bergstrasse, Germany) 2020 Jun 2;26(31):7092-7108
YBX1 mediates autophagy by targeting p110β and decreasing the sensitivity to cisplatin in NSCLC.
Cui Y, Li F, Xie Q, Zhao S, Guo T, Guo P, Hu S, Hao J, Tian C, Yu W, Li Z, Fang L, Zhao L, Chen M, Wu T, Gu C
Cell death & disease 2020 Jun 19;11(6):476
Cell death & disease 2020 Jun 19;11(6):476
Role of mitochondrial acyl-CoA dehydrogenases in the metabolism of dicarboxylic fatty acids.
Bharathi SS, Zhang Y, Gong Z, Muzumdar R, Goetzman ES
Biochemical and biophysical research communications 2020 Jun 18;527(1):162-166
Biochemical and biophysical research communications 2020 Jun 18;527(1):162-166
Drp1, a potential therapeutic target for Parkinson's disease, is involved in olfactory bulb pathological alteration in the Rotenone-induced rat model.
Zhang X, Huang W, Shao Q, Yang Y, Xu Z, Chen J, Zhang X, Ge X
Toxicology letters 2020 Jun 1;325:1-13
Toxicology letters 2020 Jun 1;325:1-13
LncRNA-H19 induces hepatic stellate cell activation via upregulating alcohol dehydrogenase III-mediated retinoic acid signals.
Wang ZM, Xia SW, Zhang T, Wang ZY, Yang X, Kai J, Cheng XD, Shao JJ, Tan SZ, Chen AP, Wang SJ, Zhang F, Zhang ZL, Zheng SZ
International immunopharmacology 2020 Jul;84:106470
International immunopharmacology 2020 Jul;84:106470
Network Pharmacology and Bioactive Equivalence Assessment Integrated Strategy Driven Q-markers Discovery for Da-Cheng-Qi Decoction to Attenuate Intestinal Obstruction.
Li D, Lv B, Wang D, Xu D, Qin S, Zhang Y, Chen J, Zhang W, Zhang Z, Xu F
Phytomedicine : international journal of phytotherapy and phytopharmacology 2020 Jul;72:153236
Phytomedicine : international journal of phytotherapy and phytopharmacology 2020 Jul;72:153236
The up-regulation of NDRG1 by HIF counteracts the cancer-promoting effect of HIF in VHL-deficient clear cell renal cell carcinoma.
Zhang ZY, Zhang SL, Chen HL, Mao YQ, Li ZM, Kong CY, Han B, Zhang J, Chen YH, Xue W, Zhai W, Wang LS
Cell proliferation 2020 Jul;53(7):e12853
Cell proliferation 2020 Jul;53(7):e12853
Pycnogenol achieves neuroprotective effects in rats with spinal cord injury by stabilizing the mitochondrial membrane potential.
Tao L, Liu X, Da W, Tao Z, Zhu Y
Neurological research 2020 Jul;42(7):597-604
Neurological research 2020 Jul;42(7):597-604
Expression of lncRNA-HOTAIR in the serum of patients with lymph node metastasis of papillary thyroid carcinoma and its impact.
Wu L, Shi Y, Liu B, Zhao M
Oncology letters 2020 Jul;20(1):907-913
Oncology letters 2020 Jul;20(1):907-913
Leucine-rich α-2-glycoprotein-1 promotes diabetic corneal epithelial wound healing and nerve regeneration via regulation of matrix metalloproteinases.
Li W, Wang X, Cheng J, Li J, Wang Q, Zhou Q, Li H, Xue J, Zhang Y, Yang L, Xie L
Experimental eye research 2020 Jul;196:108060
Experimental eye research 2020 Jul;196:108060
Fingolimod (FTY720) improves postoperative cognitive dysfunction in mice subjected to D-galactose-induced aging.
Zhang J, Xiao B, Li CX, Wang Y
Neural regeneration research 2020 Jul;15(7):1308-1315
Neural regeneration research 2020 Jul;15(7):1308-1315
Resveratrol slows the tumourigenesis of pancreatic cancer by inhibiting NFκB activation.
Qian W, Xiao Q, Wang L, Qin T, Xiao Y, Li J, Yue Y, Zhou C, Duan W, Ma Q, Ma J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jul;127:110116
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jul;127:110116
The Establishment and Application Studies on Precise Lysosome pH Indicator Based on Self-Decomposable Nanoparticles.
Pang C, Song C, Li Y, Wang Q, Zhu X, Wu J, Tian Y, Fan H, Hu J, Li C, Wang B, Li X, Liu W, Fan L
Nanoscale research letters 2020 Jul 8;15(1):143
Nanoscale research letters 2020 Jul 8;15(1):143
PD-L1 promotes tumor growth and progression by activating WIP and β-catenin signaling pathways and predicts poor prognosis in lung cancer.
Yu W, Hua Y, Qiu H, Hao J, Zou K, Li Z, Hu S, Guo P, Chen M, Sui S, Xiong Y, Li F, Lu J, Guo W, Luo G, Deng W
Cell death & disease 2020 Jul 6;11(7):506
Cell death & disease 2020 Jul 6;11(7):506
Elevated expression of minichromosome maintenance 3 indicates poor outcomes and promotes G1/S cell cycle progression, proliferation, migration and invasion in colorectal cancer.
Zhou H, Xiong Y, Zhang G, Liu Z, Li L, Hou S, Zhou T
Bioscience reports 2020 Jul 31;40(7)
Bioscience reports 2020 Jul 31;40(7)
miR-5089-5p suppresses castration-resistant prostate cancer resistance to enzalutamide and metastasis via miR-5089-5p/SPINK1/ MAPK/MMP9 signaling.
Wang ZC, Li Y, Wang KL, Wang L, You BS, Zhao DF, Liu ZQ, Fang RZ, Wang JQ, Zhang W, Zhang JM, Xu WH
Aging 2020 Jul 21;12(14):14418-14433
Aging 2020 Jul 21;12(14):14418-14433
Nintedanib Reduces Neutrophil Chemotaxis via Activating GRK2 in Bleomycin-Induced Pulmonary Fibrosis.
Chen WC, Chen NJ, Chen HP, Yu WK, Su VY, Chen H, Wu HH, Yang KY
International journal of molecular sciences 2020 Jul 2;21(13)
International journal of molecular sciences 2020 Jul 2;21(13)
Myeloid cells protect intestinal epithelial barrier integrity through the angiogenin/plexin-B2 axis.
Bai R, Sun D, Chen M, Shi X, Luo L, Yao Z, Liu Y, Ge X, Gao X, Hu GF, Zhou W, Sheng J, Xu Z
The EMBO journal 2020 Jul 1;39(13):e103325
The EMBO journal 2020 Jul 1;39(13):e103325
Euscaphic acid and Tormentic acid protect vascular endothelial cells against hypoxia-induced apoptosis via PI3K/AKT or ERK 1/2 signaling pathway.
Shi C, Li Z, Wu Y, Li X, Li Y, Wei J, Li J, Zhang Y, Li L
Life sciences 2020 Jul 1;252:117666
Life sciences 2020 Jul 1;252:117666
Antitumor activity of celastrol by inhibition of proliferation, invasion, and migration in cholangiocarcinoma via PTEN/PI3K/Akt pathway.
Zhu B, Wei Y
Cancer medicine 2020 Jan;9(2):783-796
Cancer medicine 2020 Jan;9(2):783-796
PRRX1-induced epithelial-to-mesenchymal transition in salivary adenoid cystic carcinoma activates the metabolic reprogramming of free fatty acids to promote invasion and metastasis.
Jiang YP, Tang YL, Wang SS, Wu JS, Zhang M, Pang X, Wu JB, Chen Y, Tang YJ, Liang XH
Cell proliferation 2020 Jan;53(1):e12705
Cell proliferation 2020 Jan;53(1):e12705
α-Ketoglutarate Modulates Macrophage Polarization Through Regulation of PPARγ Transcription and mTORC1/p70S6K Pathway to Ameliorate ALI/ARDS.
Liu M, Chen Y, Wang S, Zhou H, Feng D, Wei J, Shi X, Wu L, Zhang P, Yang H, Lv X
Shock (Augusta, Ga.) 2020 Jan;53(1):103-113
Shock (Augusta, Ga.) 2020 Jan;53(1):103-113
MiR-22 restrains proliferation of rheumatoid arthritis by targeting IL6R and may be concerned with the suppression of NF-κB pathway.
Yang QY, Yang KP, Li ZZ
The Kaohsiung journal of medical sciences 2020 Jan;36(1):20-26
The Kaohsiung journal of medical sciences 2020 Jan;36(1):20-26
Scavenger receptor A impairs interferon response to HBV infection by limiting TRAF3 ubiquitination through recruiting OTUB1.
Xie M, Yin Y, Chen L, Yin A, Liu Y, Liu Y, Dong L, Lai Q, Zhou J, Zhang L, Xu M, Chen Z, Zuo D
The FEBS journal 2020 Jan;287(2):310-324
The FEBS journal 2020 Jan;287(2):310-324
Fluoride induced mitochondrial impairment and PINK1-mediated mitophagy in Leydig cells of mice: In vivo and in vitro studies.
Liang C, Gao Y, He Y, Han Y, Manthari RK, Tikka C, Chen C, Wang J, Zhang J
Environmental pollution (Barking, Essex : 1987) 2020 Jan;256:113438
Environmental pollution (Barking, Essex : 1987) 2020 Jan;256:113438
NRSN2 promotes breast cancer metastasis by activating PI3K/AKT/mTOR and NF-κB signaling pathways.
Ren F, Zhang W, Lu S, Ren H, Guo Y
Oncology letters 2020 Jan;19(1):813-823
Oncology letters 2020 Jan;19(1):813-823
LINC00365-SCGB2A1 axis inhibits the viability of breast cancer through targeting NF-κB signaling.
Zhang L, Yan X, Yu S, Zhong X, Tian R, Xu L, Bian X, Su J
Oncology letters 2020 Jan;19(1):753-762
Oncology letters 2020 Jan;19(1):753-762
MicroRNA-150 functions as a tumor suppressor and sensitizes osteosarcoma to doxorubicin-induced apoptosis by targeting RUNX2.
Ling Z, Fan G, Yao D, Zhao J, Zhou Y, Feng J, Zhou G, Chen Y
Experimental and therapeutic medicine 2020 Jan;19(1):481-488
Experimental and therapeutic medicine 2020 Jan;19(1):481-488
Matrine suppresses breast cancer metastasis by targeting ITGB1 and inhibiting epithelial-to-mesenchymal transition.
Ren L, Mo W, Wang L, Wang X
Experimental and therapeutic medicine 2020 Jan;19(1):367-374
Experimental and therapeutic medicine 2020 Jan;19(1):367-374
Effect of stromal cell-derived factor-1/CXCR4 axis in neural stem cell transplantation for Parkinson's disease.
Xu JT, Qian Y, Wang W, Chen XX, Li Y, Li Y, Yang ZY, Song XB, Lu D, Deng XL
Neural regeneration research 2020 Jan;15(1):112-119
Neural regeneration research 2020 Jan;15(1):112-119
Perilla oil regulates intestinal microbiota and alleviates insulin resistance through the PI3K/AKT signaling pathway in type-2 diabetic KKAy mice.
Wang J, He Y, Yu D, Jin L, Gong X, Zhang B
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2020 Jan;135:110965
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2020 Jan;135:110965
Involvement of proliferative and apoptotic factors in the development of hindgut in rat fetuses with ethylenethiourea-induced anorectal malformations.
Long C, Xiao Y, Li S, Tang X, Yuan Z, Bai Y
Acta histochemica 2020 Jan;122(1):151466
Acta histochemica 2020 Jan;122(1):151466
Naturally-derived diterpenoid sphaeropsidin C as an activator of Nrf2/ARE pathway and its potential capability of relieving intracellular oxidative stress in human lung epithelial cells.
Li GH, Li AL, Chen XM, Zhang LY, Wang T, Wang XN, Shen T
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jan;121:109669
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jan;121:109669
Human umbilical cord blood mononuclear cells protect against renal tubulointerstitial fibrosis in cisplatin-treated rats.
Li XW, Feng LX, Zhu XJ, Liu Q, Wang HS, Wu X, Yan P, Duan XJ, Xiao YQ, Cheng W, Peng JC, Zhao F, Deng YH, Duan SB
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jan;121:109310
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jan;121:109310
Deoxycholic Acid Upregulates the Reprogramming Factors KFL4 and OCT4 Through the IL-6/STAT3 Pathway in Esophageal Adenocarcinoma Cells.
Chen M, Ye A, Wei J, Wang R, Poon K
Technology in cancer research & treatment 2020 Jan-Dec;19:1533033820945302
Technology in cancer research & treatment 2020 Jan-Dec;19:1533033820945302
Odor-mediated contextual learning induced memory consolidation and hippocampus development in neonate rat.
Cao J, Xu J, Chen S, Fan F, Chen M, Liu F, Li G
Neuroreport 2020 Jan 8;31(1):64-68
Neuroreport 2020 Jan 8;31(1):64-68
Aspirin enhances the sensitivity of colon cancer cells to cisplatin by abrogating the binding of NF-κB to the COX-2 promoter.
Jiang W, Yan Y, Chen M, Luo G, Hao J, Pan J, Hu S, Guo P, Li W, Wang R, Zuo Y, Sun Y, Sui S, Yu W, Pan Z, Zou K, Zheng Z, Deng W, Wu X, Guo W
Aging 2020 Jan 6;12(1):611-627
Aging 2020 Jan 6;12(1):611-627
Protective effects of Salidroside on spermatogenesis in streptozotocin induced type-1 diabetic male mice by inhibiting oxidative stress mediated blood-testis barrier damage.
Jiang YP, Ye RJ, Yang JM, Liu N, Zhang WJ, Ma L, Sun T, Niu JG, Zheng P, Yu JQ
Chemico-biological interactions 2020 Jan 5;315:108869
Chemico-biological interactions 2020 Jan 5;315:108869
Suppression of Notch Signaling Stimulates Progesterone Synthesis by Enhancing the Expression of NR5A2 and NR2F2 in Porcine Granulosa Cells.
Guo R, Chen F, Shi Z
Genes 2020 Jan 22;11(2)
Genes 2020 Jan 22;11(2)
Romo1 is involved in the immune response of glioblastoma by regulating the function of macrophages.
Sun G, Cao Y, Qian C, Wan Z, Zhu J, Guo J, Shi L
Aging 2020 Jan 16;12(2):1114-1127
Aging 2020 Jan 16;12(2):1114-1127
The testis-specific gene 1700102P08Rik is essential for male fertility.
Wu XL, Yun DM, Gao S, Liang AJ, Duan ZZ, Wang HS, Wang GS, Sun F
Molecular reproduction and development 2020 Feb;87(2):231-240
Molecular reproduction and development 2020 Feb;87(2):231-240
Asiaticoside nitric oxide gel accelerates diabetic cutaneous ulcers healing by activating Wnt/β-catenin signaling pathway.
Nie X, Zhang H, Shi X, Zhao J, Chen Y, Wu F, Yang J, Li X
International immunopharmacology 2020 Feb;79:106109
International immunopharmacology 2020 Feb;79:106109
FLI1 promotes protein translation via the transcriptional regulation of MKNK1 expression.
Wang C, Song J, Liu W, Yao Y, Kapranov P, Sample KM, Gajendran B, Zacksenhaus E, Hao X, Ben-David Y
International journal of oncology 2020 Feb;56(2):430-438
International journal of oncology 2020 Feb;56(2):430-438
Screening for reproductive biomarkers in Bactrian camel via iTRAQ analysis of proteomes.
Wang Q, Zhang Q, Gan Z, Li H, Yang Y, Zhang Y, Zhao X
Reproduction in domestic animals = Zuchthygiene 2020 Feb;55(2):189-199
Reproduction in domestic animals = Zuchthygiene 2020 Feb;55(2):189-199
Resveratrol Downregulates STAT3 Expression and Astrocyte Activation in Primary Astrocyte Cultures of Rat.
Wu M, Wang L, Li F, Hu R, Ma J, Zhang K, Cheng X
Neurochemical research 2020 Feb;45(2):455-464
Neurochemical research 2020 Feb;45(2):455-464
Dendrobium Alkaloids Promote Neural Function After Cerebral Ischemia-Reperfusion Injury Through Inhibiting Pyroptosis Induced Neuronal Death in both In Vivo and In Vitro Models.
Liu D, Dong Z, Xiang F, Liu H, Wang Y, Wang Q, Rao J
Neurochemical research 2020 Feb;45(2):437-454
Neurochemical research 2020 Feb;45(2):437-454
Study of the protective effect on damaged intestinal epithelial cells of rat multilineage-differentiating stress-enduring (Muse) cells.
Sun D, Yang L, Cao H, Shen ZY, Song HL
Cell biology international 2020 Feb;44(2):549-559
Cell biology international 2020 Feb;44(2):549-559
Programmed cell death protein 1 promotes hepatitis B virus transmission through the regulation of ERK1/2-mediated trophoblasts differentiation.
Yang J, Liu J, Sheng M, Zhang X, Liu M
Archives of gynecology and obstetrics 2020 Feb;301(2):551-558
Archives of gynecology and obstetrics 2020 Feb;301(2):551-558
Anti-insulin resistance effects of salidroside through mitochondrial quality control.
You B, Dun Y, Zhang W, Jiang L, Li H, Xie M, Liu Y, Liu S
The Journal of endocrinology 2020 Feb;244(2):383-393
The Journal of endocrinology 2020 Feb;244(2):383-393
Inhibition of PFKFB3 suppresses osteoclastogenesis and prevents ovariectomy-induced bone loss.
Wang J, Guan H, Liu H, Lei Z, Kang H, Guo Q, Dong Y, Liu H, Sun Y, Fang Z, Li F
Journal of cellular and molecular medicine 2020 Feb;24(3):2294-2307
Journal of cellular and molecular medicine 2020 Feb;24(3):2294-2307
Post-production modifications of murine mesenchymal stem cell (mMSC) derived extracellular vesicles (EVs) and impact on their cellular interaction.
Le Saux S, Aarrass H, Lai-Kee-Him J, Bron P, Armengaud J, Miotello G, Bertrand-Michel J, Dubois E, George S, Faklaris O, Devoisselle JM, Legrand P, Chopineau J, Morille M
Biomaterials 2020 Feb;231:119675
Biomaterials 2020 Feb;231:119675
CMIP promotes Herceptin resistance of HER2 positive gastric cancer cells.
Xiang R, Han X, Ding K, Wu Z
Pathology, research and practice 2020 Feb;216(2):152776
Pathology, research and practice 2020 Feb;216(2):152776
Inhibition of calcineurin/NFATc4 signaling attenuates ventilator‑induced lung injury.
Li M, Fang XZ, Liu XT, Zheng YF, Xie YB, Ma XD, Xia Y, Shao DH
Molecular medicine reports 2020 Feb;21(2):607-614
Molecular medicine reports 2020 Feb;21(2):607-614
Effects of dexmedetomidine on oxidative stress and inflammatory response in lungs during mechanical ventilation in COPD rats.
Li P, Han J, Zhang D, Cao S, Su C
Experimental and therapeutic medicine 2020 Feb;19(2):1219-1224
Experimental and therapeutic medicine 2020 Feb;19(2):1219-1224
Isorhamnetin attenuates Streptococcus suis virulence by inhibiting the inflammatory response.
Li G, Wang G, Wang S, Sun M, Wen Z
Antonie van Leeuwenhoek 2020 Feb;113(2):303-310
Antonie van Leeuwenhoek 2020 Feb;113(2):303-310
Targeting the miR-122/PKM2 autophagy axis relieves arsenic stress.
Wang Y, Zhao H, Guo M, Fei D, Zhang L, Xing M
Journal of hazardous materials 2020 Feb 5;383:121217
Journal of hazardous materials 2020 Feb 5;383:121217
A20 targets PFKL and glycolysis to inhibit the progression of hepatocellular carcinoma.
Feng Y, Zhang Y, Cai Y, Liu R, Lu M, Li T, Fu Y, Guo M, Huang H, Ou Y, Chen Y
Cell death & disease 2020 Feb 3;11(2):89
Cell death & disease 2020 Feb 3;11(2):89
Colorectal cancer-derived exosomal miR-106b-3p promotes metastasis by down-regulating DLC-1 expression.
Liu H, Liu Y, Sun P, Leng K, Xu Y, Mei L, Han P, Zhang B, Yao K, Li C, Bai J, Cui B
Clinical science (London, England : 1979) 2020 Feb 28;134(4):419-434
Clinical science (London, England : 1979) 2020 Feb 28;134(4):419-434
Minicircle DNA vector expressing interferon-lambda-3 inhibits hepatitis B virus replication and expression in hepatocyte-derived cell line.
Guo X, Chen D, Cai Q, Huang Z, Xu W, Peng L, Chen P
BMC molecular and cell biology 2020 Feb 18;21(1):6
BMC molecular and cell biology 2020 Feb 18;21(1):6
A tropomyosin-like Meretrix meretrix Linnaeus polypeptide inhibits the proliferation and metastasis of glioma cells via microtubule polymerization and FAK/Akt/MMPs signaling.
Fan Z, Xu Q, Wang C, Lin X, Zhang Q, Wu N
International journal of biological macromolecules 2020 Feb 15;145:154-164
International journal of biological macromolecules 2020 Feb 15;145:154-164
Transactivation of miR-202-5p by Steroidogenic Factor 1 (SF1) Induces Apoptosis in Goat Granulosa Cells by Targeting TGFβR2.
Ding Q, Jin M, Wang Y, Liu J, Kalds P, Wang Y, Yang Y, Wang X, Chen Y
Cells 2020 Feb 14;9(2)
Cells 2020 Feb 14;9(2)
GPAT3 deficiency alleviates insulin resistance and hepatic steatosis in a mouse model of severe congenital generalized lipodystrophy.
Gao M, Liu L, Wang X, Mak HY, Liu G, Yang H
Human molecular genetics 2020 Feb 1;29(3):432-443
Human molecular genetics 2020 Feb 1;29(3):432-443
Protection of diabetes-induced kidney injury by phosphocreatine via the regulation of ERK/Nrf2/HO-1 signaling pathway.
Shopit A, Niu M, Wang H, Tang Z, Li X, Tesfaldet T, Ai J, Ahmad N, Al-Azab M, Tang Z
Life sciences 2020 Feb 1;242:117248
Life sciences 2020 Feb 1;242:117248
Fine-tuning of the respiratory complexes stability and supercomplexes assembly in cells defective of complex III.
Tropeano CV, Aleo SJ, Zanna C, Roberti M, Scandiffio L, Loguercio Polosa P, Fiori J, Porru E, Roda A, Carelli V, Steimle S, Daldal F, Rugolo M, Ghelli A
Biochimica et biophysica acta. Bioenergetics 2020 Feb 1;1861(2):148133
Biochimica et biophysica acta. Bioenergetics 2020 Feb 1;1861(2):148133
MicroRNA-217 ameliorates inflammatory damage of endothelial cells induced by oxidized LDL by targeting EGR1.
Yang X, Li D, Qi YZ, Chen W, Yang CH, Jiang YH
Molecular and cellular biochemistry 2020 Dec;475(1-2):41-51
Molecular and cellular biochemistry 2020 Dec;475(1-2):41-51
Alprostadil attenuates LPS-induced cardiomyocyte injury by inhibiting the Wnt5a/JNK/NF-κB pathway.
Yu T, Dong D, Guan J, Sun J, Guo M, Wang Q
Herz 2020 Dec;45(Suppl 1):130-138
Herz 2020 Dec;45(Suppl 1):130-138
Exogenous CGRP Regulates Apoptosis and Autophagy to Alleviate Traumatic Brain Injury Through Akt/mTOR Signalling Pathway.
Tian J, Yang L, Wang P, Yang L, Fan Z
Neurochemical research 2020 Dec;45(12):2926-2938
Neurochemical research 2020 Dec;45(12):2926-2938
Acylglycerol kinase promotes the stemness of nasopharyngeal carcinoma cells by promoting β-catenin translocation to the nucleus through activating PI3K/Akt pathway.
Zhao Q, Sun P, Qin S, Liu J
Environmental toxicology 2020 Dec;35(12):1299-1307
Environmental toxicology 2020 Dec;35(12):1299-1307
Myeloid-derived suppressor cells promote epithelial ovarian cancer cell stemness by inducing the CSF2/p-STAT3 signalling pathway.
Li X, Wang J, Wu W, Gao H, Liu N, Zhan G, Li L, Han L, Guo X
The FEBS journal 2020 Dec;287(23):5218-5235
The FEBS journal 2020 Dec;287(23):5218-5235
Co-delivery of paclitaxel and anti-VEGF siRNA by tripeptide lipid nanoparticle to enhance the anti-tumor activity for lung cancer therapy.
Zhang C, Zhao Y, Zhang E, Jiang M, Zhi D, Chen H, Cui S, Zhen Y, Cui J, Zhang S
Drug delivery 2020 Dec;27(1):1397-1411
Drug delivery 2020 Dec;27(1):1397-1411
Poldip2 mediates blood-brain barrier disruption and cerebral edema by inducing AQP4 polarity loss in mouse bacterial meningitis model.
Gao M, Lu W, Shu Y, Yang Z, Sun S, Xu J, Gan S, Zhu S, Qiu G, Zhuo F, Xu S, Wang Y, Chen J, Wu X, Huang J
CNS neuroscience & therapeutics 2020 Dec;26(12):1288-1302
CNS neuroscience & therapeutics 2020 Dec;26(12):1288-1302
Inhibition of miRNA-29a regulates intestinal barrier function in diarrhea-predominant irritable bowel syndrome by upregulating ZO-1 and CLDN1.
Zhu H, Xiao X, Shi Y, Wu Y, Huang Y, Li D, Xiong F, He G, Chai Y, Tang H
Experimental and therapeutic medicine 2020 Dec;20(6):155
Experimental and therapeutic medicine 2020 Dec;20(6):155
Baicalin reversal of DNA hypermethylation-associated Klotho suppression ameliorates renal injury in type 1 diabetic mouse model.
Zhang XT, Wang G, Ye LF, Pu Y, Li RT, Liang J, Wang L, Lee KKH, Yang X
Cell cycle (Georgetown, Tex.) 2020 Dec;19(23):3329-3347
Cell cycle (Georgetown, Tex.) 2020 Dec;19(23):3329-3347
Functional Food XingJiuTang Attenuates Alcohol-Induced Liver Injury by Regulating SIRT1/Nrf-2 Signaling Pathway.
Hao J, Ding Y, Shi W, Zhang C, Li R
Chemistry & biodiversity 2020 Dec;17(12):e2000619
Chemistry & biodiversity 2020 Dec;17(12):e2000619
TLR4 inhibition ameliorates mesencephalic substantia nigra injury in neonatal rats exposed to lipopolysaccharide via regulation of neuro-immunity.
He W, Jiang M, Mao P, Yan F
Brain research bulletin 2020 Dec;165:90-96
Brain research bulletin 2020 Dec;165:90-96
Saikosaponin-d impedes hippocampal neurogenesis and causes cognitive deficits by inhibiting the survival of neural stem/progenitor cells via neurotrophin receptor signaling in mice.
Qin T, Yuan Z, Yu J, Fu X, Deng X, Fu Q, Ma Z, Ma S
Clinical and translational medicine 2020 Dec;10(8):e243
Clinical and translational medicine 2020 Dec;10(8):e243
Transforming growth factor beta type 1 (TGF-β) and hypoxia-inducible factor 1 (HIF-1) transcription complex as master regulators of the immunosuppressive protein galectin-9 expression in human cancer and embryonic cells.
Selnø ATH, Schlichtner S, Yasinska IM, Sakhnevych SS, Fiedler W, Wellbrock J, Klenova E, Pavlova L, Gibbs BF, Degen M, Schnyder I, Aliu N, Berger SM, Fasler-Kan E, Sumbayev VV
Aging 2020 Dec 8;12(23):23478-23496
Aging 2020 Dec 8;12(23):23478-23496
MicroRNA-410-3p Binds to TLR2 and Alleviates Myocardial Mitochondrial Dysfunction and Chemokine Production in LPS-Induced Sepsis.
Zuo T, Tang Q, Zhang X, Shang F
Molecular therapy. Nucleic acids 2020 Dec 4;22:273-284
Molecular therapy. Nucleic acids 2020 Dec 4;22:273-284
Curcumin protects rat hippocampal neurons against pseudorabies virus by regulating the BDNF/TrkB pathway.
Yang B, Luo G, Zhang C, Feng L, Luo X, Gan L
Scientific reports 2020 Dec 17;10(1):22204
Scientific reports 2020 Dec 17;10(1):22204
Multi-walled carbon nanotubes decrease neuronal NO synthase in 3D brain organoids.
Jiang Y, Gong H, Jiang S, She C, Cao Y
The Science of the total environment 2020 Dec 15;748:141384
The Science of the total environment 2020 Dec 15;748:141384
Decreased Expression of the Host Long-Noncoding RNA-GM Facilitates Viral Escape by Inhibiting the Kinase activity TBK1 via S-glutathionylation.
Wang Y, Wang P, Zhang Y, Xu J, Li Z, Li Z, Zhou Z, Liu L, Cao X
Immunity 2020 Dec 15;53(6):1168-1181.e7
Immunity 2020 Dec 15;53(6):1168-1181.e7
Initiation of PI3K/AKT pathway by IGF-1 decreases spinal cord injury-induced endothelial apoptosis and microvascular damage.
Li H, Kong R, Wan B, Yang L, Zhang S, Cao X, Chen H
Life sciences 2020 Dec 15;263:118572
Life sciences 2020 Dec 15;263:118572
Discovery of potent small molecule PROTACs targeting mutant EGFR.
Zhao HY, Yang XY, Lei H, Xi XX, Lu SM, Zhang JJ, Xin M, Zhang SQ
European journal of medicinal chemistry 2020 Dec 15;208:112781
European journal of medicinal chemistry 2020 Dec 15;208:112781
An autoregulatory feedback loop of miR-21/VMP1 is responsible for the abnormal expression of miR-21 in colorectal cancer cells.
Wang C, Peng R, Zeng M, Zhang Z, Liu S, Jiang D, Lu Y, Zou F
Cell death & disease 2020 Dec 14;11(12):1067
Cell death & disease 2020 Dec 14;11(12):1067
Indoxyl sulfate promotes osteogenic differentiation of vascular smooth muscle cells by miR-155-5p-dependent downregulation of matrix Gla protein via ROS/NF-κB signaling.
He X, Wang Z, Wei L, Cheng X, Chen L, Gao F, Jiang H
Experimental cell research 2020 Dec 1;397(1):112301
Experimental cell research 2020 Dec 1;397(1):112301
Berberine alleviates cisplatin-induced acute kidney injury by regulating mitophagy via PINK 1/Parkin pathway.
Qi J, Xue Q, Kuang L, Xie L, Luo R, Nie X
Translational andrology and urology 2020 Aug;9(4):1712-1724
Translational andrology and urology 2020 Aug;9(4):1712-1724
Minocycline prevents the depressive-like behavior through inhibiting the release of HMGB1 from microglia and neurons.
Wang B, Huang X, Pan X, Zhang T, Hou C, Su WJ, Liu LL, Li JM, Wang YX
Brain, behavior, and immunity 2020 Aug;88:132-143
Brain, behavior, and immunity 2020 Aug;88:132-143
Melatonin Ameliorates Renal Fibrosis Through the Inhibition of NF-κB and TGF-β1/Smad3 Pathways in db/db Diabetic Mice.
Fan Z, Qi X, Yang W, Xia L, Wu Y
Archives of medical research 2020 Aug;51(6):524-534
Archives of medical research 2020 Aug;51(6):524-534
LncRNA XIST promotes chemoresistance of breast cancer cells to doxorubicin by sponging miR-200c-3p to upregulate ANLN.
Zhang M, Wang F, Xiang Z, Huang T, Zhou WB
Clinical and experimental pharmacology & physiology 2020 Aug;47(8):1464-1472
Clinical and experimental pharmacology & physiology 2020 Aug;47(8):1464-1472
Role of the Nucleotide-Binding Domain-Like Receptor Protein 3 Inflammasome in the Endothelial Dysfunction of Early Sepsis.
Luo M, Meng J, Yan J, Shang F, Zhang T, Lv D, Li C, Yang X, Luo S
Inflammation 2020 Aug;43(4):1561-1571
Inflammation 2020 Aug;43(4):1561-1571
Integrin-α9 and Its Corresponding Ligands Play Regulatory Roles in Chronic Periodontitis.
Xu S, Jiang C, Liu H, Zhang H, Liao H, Wang X, Yao S, Ma L, Guo Y, Cao Z
Inflammation 2020 Aug;43(4):1488-1497
Inflammation 2020 Aug;43(4):1488-1497
The metabolic changes in the hippocampus of an atherosclerotic rat model and the regulation of aerobic training.
Liu B, Li J, Lin X, Hu J, Lou S
Metabolic brain disease 2020 Aug;35(6):1017-1034
Metabolic brain disease 2020 Aug;35(6):1017-1034
USP30 sets a trigger threshold for PINK1-PARKIN amplification of mitochondrial ubiquitylation.
Rusilowicz-Jones EV, Jardine J, Kallinos A, Pinto-Fernandez A, Guenther F, Giurrandino M, Barone FG, McCarron K, Burke CJ, Murad A, Martinez A, Marcassa E, Gersch M, Buckmelter AJ, Kayser-Bricker KJ, Lamoliatte F, Gajbhiye A, Davis S, Scott HC, Murphy E, England K, Mortiboys H, Komander D, Trost M, Kessler BM, Ioannidis S, Ahlijanian MK, Urbé S, Clague MJ
Life science alliance 2020 Aug;3(8)
Life science alliance 2020 Aug;3(8)
PRDM16 orchestrates angiogenesis via neural differentiation in the developing brain.
Su L, Lei X, Ma H, Feng C, Jiang J, Jiao J
Cell death and differentiation 2020 Aug;27(8):2313-2329
Cell death and differentiation 2020 Aug;27(8):2313-2329
MiR-34a affects G2 arrest in prostate cancer PC3 cells via Wnt pathway and inhibits cell growth and migration.
Dong B, Xu GC, Liu ST, Liu T, Geng B
European review for medical and pharmacological sciences 2020 Aug;24(16):8349-8358
European review for medical and pharmacological sciences 2020 Aug;24(16):8349-8358
Vitamin D3 protects articular cartilage by inhibiting the Wnt/β-catenin signaling pathway.
Yang T, Sun W, Duan YH, Sun YB, Ren YM, Hou WY, Tian MQ
Experimental and therapeutic medicine 2020 Aug;20(2):1775-1781
Experimental and therapeutic medicine 2020 Aug;20(2):1775-1781
Graphene oxide size-dependently altered lipid profiles in THP-1 macrophages.
Luo Y, Peng J, Huang C, Cao Y
Ecotoxicology and environmental safety 2020 Aug;199:110714
Ecotoxicology and environmental safety 2020 Aug;199:110714
Identification of EMT-related high-risk stage II colorectal cancer and characterisation of metastasis-related genes.
Wang K, Song K, Ma Z, Yao Y, Liu C, Yang J, Xiao H, Zhang J, Zhang Y, Zhao W
British journal of cancer 2020 Aug;123(3):410-417
British journal of cancer 2020 Aug;123(3):410-417
Activation of the Hedgehog Pathway Promotes Recovery of Neurological Function After Traumatic Brain Injury by Protecting the Neurovascular Unit.
Wu J, He J, Tian X, Zhong J, Li H, Sun X
Translational stroke research 2020 Aug;11(4):720-733
Translational stroke research 2020 Aug;11(4):720-733
A mutation found in esophageal cancer alters integrin β4 mRNA splicing.
Kelly GT, Faraj R, Dai Z, Cress AE, Wang T
Biochemical and biophysical research communications 2020 Aug 27;529(3):726-732
Biochemical and biophysical research communications 2020 Aug 27;529(3):726-732
BCCIPβ facilitates p53 ubiquitination via binding with E6 protein in high-risk HPV positive head and neck squamous cell carcinoma.
Wang F, Wang J, Wang J, Zhang L, Fu H, Li J, Tian T, Zuo J, Lv W, Ma X
Biochemical and biophysical research communications 2020 Aug 27;529(3):685-691
Biochemical and biophysical research communications 2020 Aug 27;529(3):685-691
FB-15 inhibits MGC-803 cells growth by regulating energy metabolism.
Deng X, Pi Y, Li Z, Xiong R, Liu J, Zhao J, Xie Z, Lei X, Tang G
Chemico-biological interactions 2020 Aug 25;327:109186
Chemico-biological interactions 2020 Aug 25;327:109186
BVES downregulation in non-syndromic tetralogy of fallot is associated with ventricular outflow tract stenosis.
Shi Y, Li Y, Wang Y, Zhu P, Chen Y, Wang H, Yue S, Xia X, Chen J, Jiang Z, Zhou C, Cai W, Yuan H, Wu Y, Wan Y, Li X, Zhu X, Zhou Z, Dai G, Li F, Mo X, Ye X, Fan X, Zhuang J, Wu X, Yuan W
Scientific reports 2020 Aug 25;10(1):14167
Scientific reports 2020 Aug 25;10(1):14167
ZEB1-Mediated Transcriptional Upregulation of circWWC3 Promotes Breast Cancer Progression through Activating Ras Signaling Pathway.
Meng L, Liu S, Liu F, Sang M, Ju Y, Fan X, Gu L, Li Z, Geng C, Sang M
Molecular therapy. Nucleic acids 2020 Aug 19;22:124-137
Molecular therapy. Nucleic acids 2020 Aug 19;22:124-137
Computational repositioning of dimethyl fumarate for treating alcoholic liver disease.
Zhang Y, Zhao S, Fu Y, Yan L, Feng Y, Chen Y, Wu Y, Deng Y, Zhang G, Chen Z, Chen Y, Liu T
Cell death & disease 2020 Aug 18;11(8):641
Cell death & disease 2020 Aug 18;11(8):641
Silychristin A activates Nrf2-HO-1/SOD2 pathway to reduce apoptosis and improve GLP-1 production through upregulation of estrogen receptor α in GLUTag cells.
Wang J, Zhang X, Zhang L, Yan T, Wu B, Xu F, Jia Y
European journal of pharmacology 2020 Aug 15;881:173236
European journal of pharmacology 2020 Aug 15;881:173236
Metformin ameliorates cardiac conduction delay by regulating microRNA-1 in mice.
Lv L, Zheng N, Zhang L, Li R, Li Y, Yang R, Li C, Fang R, Shabanova A, Li X, Liu Y, Liang H, Zhou Y, Shan H
European journal of pharmacology 2020 Aug 15;881:173131
European journal of pharmacology 2020 Aug 15;881:173131
Antagomirs targeting miR-142-5p attenuate pilocarpine-induced status epilepticus in mice.
Zhang H, Lian Y, Xie N, Cheng X, Chen C, Xu H, Zheng Y
Experimental cell research 2020 Aug 15;393(2):112089
Experimental cell research 2020 Aug 15;393(2):112089
Sulforaphane enhances the cisplatin sensitivity through regulating DNA repair and accumulation of intracellular cisplatin in ovarian cancer cells.
Gong TT, Liu XD, Zhan ZP, Wu QJ
Experimental cell research 2020 Aug 15;393(2):112061
Experimental cell research 2020 Aug 15;393(2):112061
HIF-1α-upregulated lncRNA-H19 regulates lipid droplet metabolism through the AMPKα pathway in hepatic stellate cells.
Wang Z, Yang X, Kai J, Wang F, Wang Z, Shao J, Tan S, Chen A, Zhang F, Wang S, Zhang Z, Zheng S
Life sciences 2020 Aug 15;255:117818
Life sciences 2020 Aug 15;255:117818
Progesterone promotes endothelial nitric oxide synthase expression through enhancing nuclear progesterone receptor-SP-1 formation.
You Y, Tan W, Guo Y, Luo M, Shang FF, Xia Y, Luo S
American journal of physiology. Heart and circulatory physiology 2020 Aug 1;319(2):H341-H348
American journal of physiology. Heart and circulatory physiology 2020 Aug 1;319(2):H341-H348
A multi-scale systems pharmacology approach uncovers the anti-cancer molecular mechanism of Ixabepilone.
Cao DS, Jiang SL, Guan YD, Chen XS, Zhang LX, Zhang Y, Chen AF, Yang JM, Cheng Y
European journal of medicinal chemistry 2020 Aug 1;199:112421
European journal of medicinal chemistry 2020 Aug 1;199:112421
Pyrazinamide alleviates rifampin-induced steatohepatitis in mice by regulating the activities of cholesterol-activated 7α-hydroxylase and lipoprotein lipase.
Tan W, Zhao K, Xiang J, Zhou X, Cao F, Song W, Liu Q, Zhang X, Li X, Tan Z
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2020 Aug 1;151:105402
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2020 Aug 1;151:105402
Exogenous hydrogen sulfide inhibits human melanoma cell development via suppression of the PI3K/AKT/ mTOR pathway.
Xiao Q, Ying J, Qiao Z, Yang Y, Dai X, Xu Z, Zhang C, Xiang L
Journal of dermatological science 2020 Apr;98(1):26-34
Journal of dermatological science 2020 Apr;98(1):26-34
Responses of intestinal morphology and function in offspring to heat stress in primiparous sows during late gestation.
Guo H, He J, Yang X, Zheng W, Yao W
Journal of thermal biology 2020 Apr;89:102539
Journal of thermal biology 2020 Apr;89:102539
Hydrogen sulfide inhibits cigarette smoke-induced inflammation and injury in alveolar epithelial cells by suppressing PHD2/HIF-1α/MAPK signaling pathway.
Guan R, Wang J, Li D, Li Z, Liu H, Ding M, Cai Z, Liang X, Yang Q, Long Z, Chen L, Liu W, Sun D, Yao H, Lu W
International immunopharmacology 2020 Apr;81:105979
International immunopharmacology 2020 Apr;81:105979
Lycopene attenuates body weight gain through induction of browning via regulation of peroxisome proliferator-activated receptor γ in high-fat diet-induced obese mice.
Zhu R, Wei J, Liu H, Liu C, Wang L, Chen B, Li L, Jia Q, Tian Y, Li R, Zhao D, Mo F, Li Y, Gao S, Wang XD, Zhang D
The Journal of nutritional biochemistry 2020 Apr;78:108335
The Journal of nutritional biochemistry 2020 Apr;78:108335
Identification of novel variants in the FZD4 gene associated with familial exudative vitreoretinopathy in Chinese families.
Xu H, Zhang S, Huang L, Zhao P, Zhang X, Yang Z, Zhang L
Clinical & experimental ophthalmology 2020 Apr;48(3):356-365
Clinical & experimental ophthalmology 2020 Apr;48(3):356-365
High- and low-virulent bovine Pasteurella multocida induced differential NLRP3 inflammasome activation and subsequent IL-1β secretion.
Fang R, Lei G, Jiang J, Du H, Liu Y, Lei Z, Ye C, Li N, Peng Y
Veterinary microbiology 2020 Apr;243:108646
Veterinary microbiology 2020 Apr;243:108646
Stromal fibroblast-derived MFAP5 promotes the invasion and migration of breast cancer cells via Notch1/slug signaling.
Chen Z, Yan X, Li K, Ling Y, Kang H
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2020 Apr;22(4):522-531
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2020 Apr;22(4):522-531
Decreased basal and stimulated salivary parameters by histopathological lesions and secretory dysfunction of parotid and submandibular glands in rats with type 2 diabetes.
Chen SY, Wang Y, Zhang CL, Yang ZM
Experimental and therapeutic medicine 2020 Apr;19(4):2707-2719
Experimental and therapeutic medicine 2020 Apr;19(4):2707-2719
Novel nortriterpenoids with new skeletons and limonoids from the fruits of Evodia rutaecarpa and their bioactivities.
Shi YS, Xia HM, Wu CH, Li CB, Duan CC, Che C, Zhang XJ, Li HT, Zhang Y, Zhang XF
Fitoterapia 2020 Apr;142:104503
Fitoterapia 2020 Apr;142:104503
SMAD3/SP1 complex-mediated constitutive active loop between lncRNA PCAT7 and TGF-β signaling promotes prostate cancer bone metastasis.
Lang C, Dai Y, Wu Z, Yang Q, He S, Zhang X, Guo W, Lai Y, Du H, Wang H, Ren D, Peng X
Molecular oncology 2020 Apr;14(4):808-828
Molecular oncology 2020 Apr;14(4):808-828
Paradoxical Pro-inflammatory Responses by Human Macrophages to an Amoebae Host-Adapted Legionella Effector.
Price C, Jones S, Mihelcic M, Santic M, Abu Kwaik Y
Cell host & microbe 2020 Apr 8;27(4):571-584.e7
Cell host & microbe 2020 Apr 8;27(4):571-584.e7
Calcium-sensing receptor promotes tumor proliferation and migration in human intrahepatic cholangiocarcinoma by targeting ERK signaling pathway.
Fang Y, Liu L, Liu S, Hu L, Cai W, Wan X, Liu D, He Y, Zhu Z
European journal of pharmacology 2020 Apr 5;872:172915
European journal of pharmacology 2020 Apr 5;872:172915
Ablation of glutaredoxin 1 promotes pulmonary angiogenesis and alveolar formation in hyperoxia-injured lungs by modifying HIF-1α stability and inhibiting the NF-κB pathway.
Liu X, Li K, Zhang F, Zhang Y, Deng C, Guo C
Biochemical and biophysical research communications 2020 Apr 30;525(2):528-535
Biochemical and biophysical research communications 2020 Apr 30;525(2):528-535
An inducible intestinal epithelial cell-specific NHE3 knockout mouse model mimicking congenital sodium diarrhea.
Xue J, Thomas L, Tahmasbi M, Valdez A, Dominguez Rieg JA, Fenton RA, Rieg T
Clinical science (London, England : 1979) 2020 Apr 30;134(8):941-953
Clinical science (London, England : 1979) 2020 Apr 30;134(8):941-953
RNA-seq analysis of potential lncRNAs for age-related hearing loss in a mouse model.
Zhao T, Liu X, Sun Z, Zhang J, Zhang X, Wang C, Geng R, Zheng T, Li B, Zheng QY
Aging 2020 Apr 26;12(8):7491-7510
Aging 2020 Apr 26;12(8):7491-7510
CACNA1H downregulation induces skeletal muscle atrophy involving endoplasmic reticulum stress activation and autophagy flux blockade.
Li S, Hao M, Li B, Chen M, Chen J, Tang J, Hong S, Min J, Hu M, Hong L
Cell death & disease 2020 Apr 24;11(4):279
Cell death & disease 2020 Apr 24;11(4):279
MicroRNA-183 regulates lipopolysaccharide-induced oxidative stress of hippocampal neurons by targeting the fibronectin 1 gene.
Xie Q, Feng L, Zhang C, Gan L
Neuroscience letters 2020 Apr 23;725:134902
Neuroscience letters 2020 Apr 23;725:134902
Asperosaponin VI Injection Enhances Orthodontic Tooth Movement in Rats.
Ma D, Wang X, Ren X, Bu J, Zheng D, Zhang J
Medical science monitor : international medical journal of experimental and clinical research 2020 Apr 23;26:e922372
Medical science monitor : international medical journal of experimental and clinical research 2020 Apr 23;26:e922372
Posterior Neocortex-Specific Regulation of Neuronal Migration by CEP85L Identifies Maternal Centriole-Dependent Activation of CDK5.
Kodani A, Kenny C, Lai A, Gonzalez DM, Stronge E, Sejourne GM, Isacco L, Partlow JN, O'Donnell A, McWalter K, Byrne AB, Barkovich AJ, Yang E, Hill RS, Gawlinski P, Wiszniewski W, Cohen JS, Fatemi SA, Baranano KW, Sahin M, Vossler DG, Yuskaitis CJ, Walsh CA
Neuron 2020 Apr 22;106(2):246-255.e6
Neuron 2020 Apr 22;106(2):246-255.e6
Effect of KIF22 on promoting proliferation and migration of gastric cancer cells via MAPK-ERK pathways.
Yu ZY, Jiang XY, Zhao RR, Qin JJ, Luo CJ, Ren YX, Ren W, Ma ZJ, Jiao ZY
Chinese medical journal 2020 Apr 20;133(8):919-928
Chinese medical journal 2020 Apr 20;133(8):919-928
CCL5 derived from tumor-associated macrophages promotes prostate cancer stem cells and metastasis via activating β-catenin/STAT3 signaling.
Huang R, Wang S, Wang N, Zheng Y, Zhou J, Yang B, Wang X, Zhang J, Guo L, Wang S, Chen Z, Wang Z, Xiang S
Cell death & disease 2020 Apr 16;11(4):234
Cell death & disease 2020 Apr 16;11(4):234
Histone Deacetylation 10 Alleviates Inflammation After Intracerebral Hemorrhage via the PTPN22/NLRP3 Pathway in Rats.
Wang L, Zheng S, Zhang L, Xiao H, Gan H, Chen H, Zhai X, Liang P, Zhao J, Li Y
Neuroscience 2020 Apr 15;432:247-259
Neuroscience 2020 Apr 15;432:247-259
All-trans-retinal induces autophagic cell death via oxidative stress and the endoplasmic reticulum stress pathway in human retinal pigment epithelial cells.
Zhang L, Zhou Y, Xia Q, Chen Y, Li J
Toxicology letters 2020 Apr 1;322:77-86
Toxicology letters 2020 Apr 1;322:77-86
Targeting β2 subunit of Na+/K+-ATPase induces glioblastoma cell apoptosis through elevation of intracellular Ca2.
Li S, Dai Z, Yang D, Li W, Dai H, Sun B, Liu X, Xie X, Xu R, Zhao X
American journal of cancer research 2019;9(6):1293-1308
American journal of cancer research 2019;9(6):1293-1308
p66Shc Contributes to Liver Fibrosis through the Regulation of Mitochondrial Reactive Oxygen Species.
Zhao Y, Wang Z, Feng D, Zhao H, Lin M, Hu Y, Zhang N, Lv L, Gao Z, Zhai X, Tian X, Yao J
Theranostics 2019;9(5):1510-1522
Theranostics 2019;9(5):1510-1522
LncRNA-MTA2TR functions as a promoter in pancreatic cancer via driving deacetylation-dependent accumulation of HIF-1α.
Zeng Z, Xu FY, Zheng H, Cheng P, Chen QY, Ye Z, Zhong JX, Deng SJ, Liu ML, Huang K, Li Q, Li W, Hu YH, Wang F, Wang CY, Zhao G
Theranostics 2019;9(18):5298-5314
Theranostics 2019;9(18):5298-5314
STAT3 Contributes To Oncolytic Newcastle Disease Virus-Induced Immunogenic Cell Death in Melanoma Cells.
Shao X, Wang X, Guo X, Jiang K, Ye T, Chen J, Fang J, Gu L, Wang S, Zhang G, Meng S, Xu Q
Frontiers in oncology 2019;9:436
Frontiers in oncology 2019;9:436
Antitumor Effects of Berberine on Gliomas via Inactivation of Caspase-1-Mediated IL-1β and IL-18 Release.
Tong L, Xie C, Wei Y, Qu Y, Liang H, Zhang Y, Xu T, Qian X, Qiu H, Deng H
Frontiers in oncology 2019;9:364
Frontiers in oncology 2019;9:364
PNS-R1 inhibits Dex-induced bronchial epithelial cells apoptosis in asthma through mitochondrial apoptotic pathway.
Zou W, Niu C, Fu Z, Gong C
Cell & bioscience 2019;9:18
Cell & bioscience 2019;9:18
MiR-24-3p Inhibits the Progression of Pancreatic Ductal Adenocarcinoma Through LAMB3 Downregulation.
Huang W, Gu J, Tao T, Zhang J, Wang H, Fan Y
Frontiers in oncology 2019;9:1499
Frontiers in oncology 2019;9:1499
The Binding of PD-L1 and Akt Facilitates Glioma Cell Invasion Upon Starvation via Akt/Autophagy/F-Actin Signaling.
Chen RQ, Xu XH, Liu F, Li CY, Li YJ, Li XR, Jiang GY, Hu F, Liu D, Pan F, Qiu XY, Chen XQ
Frontiers in oncology 2019;9:1347
Frontiers in oncology 2019;9:1347
Critical role of Tim-3 mediated autophagy in chronic stress induced immunosuppression.
Qin A, Zhong T, Zou H, Wan X, Yao B, Zheng X, Yin D
Cell & bioscience 2019;9:13
Cell & bioscience 2019;9:13
MTHFD1L-Mediated Redox Homeostasis Promotes Tumor Progression in Tongue Squamous Cell Carcinoma.
Li H, Fu X, Yao F, Tian T, Wang C, Yang A
Frontiers in oncology 2019;9:1278
Frontiers in oncology 2019;9:1278
Chrysanthemum extract attenuates hepatotoxicity via inhibiting oxidative stress in vivo and in vitro.
Tian Z, Jia H, Jin Y, Wang M, Kou J, Wang C, Rong X, Xie X, Han G, Pang X
Food & nutrition research 2019;63
Food & nutrition research 2019;63
Mild hypothermia improves neurological outcome in mice after cardiopulmonary resuscitation through Silent Information Regulator 1-actviated autophagy.
Wei H, Yin M, Lu Y, Yang Y, Li B, Liao XX, Dai G, Jing X, Xiong Y, Hu C
Cell death discovery 2019;5:129
Cell death discovery 2019;5:129
Inhibition of Mitochondrial Complex I Aggravates Folic Acid-Induced Acute Kidney Injury.
Zhang W, Yang Y, Gao H, Zhang Y, Jia Z, Huang S
Kidney & blood pressure research 2019;44(5):1002-1013
Kidney & blood pressure research 2019;44(5):1002-1013
SOCS3 control the activity of NF-κB induced by HSP70 via degradation of MyD88-adapter-like protein (Mal) in IPEC-J2 cells.
Yong YH, Wang P, Jia RM, Gooneratne R, Robert Wang HC, Liao M, Ju XH
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2019;36(1):151-159
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2019;36(1):151-159
UHRF1 Promotes Proliferation of Human Adipose-Derived Stem Cells and Suppresses Adipogenesis via Inhibiting Peroxisome Proliferator-Activated Receptor γ.
Chen K, Guo Z, Luo Y, Yuan J, Mo Z
BioMed research international 2019;2019:9456847
BioMed research international 2019;2019:9456847
Mechanisms of Aerobic Exercise Upregulating the Expression of Hippocampal Synaptic Plasticity-Associated Proteins in Diabetic Rats.
Li J, Liu Y, Liu B, Li F, Hu J, Wang Q, Li M, Lou S
Neural plasticity 2019;2019:7920540
Neural plasticity 2019;2019:7920540
Spica Prunellae Extract Enhances Fluorouracil Sensitivity of 5-Fluorouracil-Resistant Human Colon Carcinoma HCT-8/5-FU Cells via TOP2α and miR-494.
Fang Y, Yang C, Zhang L, Wei L, Lin J, Zhao J, Peng J
BioMed research international 2019;2019:5953619
BioMed research international 2019;2019:5953619
Hepatitis B Virus X Protein-Induced RORγ Expression to Promote the Migration and Proliferation of Hepatocellular Carcinoma.
Huang Y, Liang H, He C, Peng F
BioMed research international 2019;2019:5407126
BioMed research international 2019;2019:5407126
Primary Cilia Blockage Promotes the Malignant Behaviors of Hepatocellular Carcinoma via Induction of Autophagy.
Liu L, Sheng JQ, Wang MR, Gan Y, Wu XL, Liao JZ, Tian DA, He XX, Li PY
BioMed research international 2019;2019:5202750
BioMed research international 2019;2019:5202750
Carnosine Protects Mouse Podocytes from High Glucose Induced Apoptosis through PI3K/AKT and Nrf2 Pathways.
Zhao K, Li Y, Wang Z, Han N, Wang Y
BioMed research international 2019;2019:4348973
BioMed research international 2019;2019:4348973
Analysis of Toll-Like Receptors in Human Milk: Detection of Membrane-Bound and Soluble Forms.
Cattaneo C, Caramaschi A, Uga E, Braghin M, Cosi G, Peila C, Strozzi MC, Sabatini M, Gazzolo D, Manfredi M, Cavaletto M
Journal of immunology research 2019;2019:4078671
Journal of immunology research 2019;2019:4078671
Alleviation of Hepatic Ischemia Reperfusion Injury by Oleanolic Acid Pretreating via Reducing HMGB1 Release and Inhibiting Apoptosis and Autophagy.
Wang W, Wu L, Li J, Ji J, Chen K, Yu Q, Li S, Feng J, Liu T, Zhang J, Chen J, Zhou Y, Mao Y, Wang F, Dai W, Fan X, Guo C, Wu J
Mediators of inflammation 2019;2019:3240713
Mediators of inflammation 2019;2019:3240713
Atorvastatin Inhibits Breast Cancer Cells by Downregulating PTEN/AKT Pathway via Promoting Ras Homolog Family Member B (RhoB).
Ma Q, Gao Y, Xu P, Li K, Xu X, Gao J, Qi Y, Xu J, Yang Y, Song W, He X, Liu S, Yuan X, Yin W, He Y, Pan W, Wei L, Zhang J
BioMed research international 2019;2019:3235021
BioMed research international 2019;2019:3235021
Nrf2/Keap1/ARE Signaling Mediated an Antioxidative Protection of Human Placental Mesenchymal Stem Cells of Fetal Origin in Alveolar Epithelial Cells.
Yan X, Fu X, Jia Y, Ma X, Tao J, Yang T, Ma H, Liang X, Liu X, Yang J, Wei J
Oxidative medicine and cellular longevity 2019;2019:2654910
Oxidative medicine and cellular longevity 2019;2019:2654910
Jiawei Foshou San Induces Apoptosis in Ectopic Endometrium Based on Systems Pharmacology, Molecular Docking, and Experimental Evidence.
Wei J, Zhao B, Zhang C, Shen B, Zhang Y, Li C, Chen Y
Evidence-based complementary and alternative medicine : eCAM 2019;2019:2360367
Evidence-based complementary and alternative medicine : eCAM 2019;2019:2360367
Jiedu Sangen Decoction Inhibits the Invasion and Metastasis of Colorectal Cancer Cells by Regulating EMT through the Hippo Signaling Pathway.
Yuan L, Zhou M, Wasan HS, Zhang K, Li Z, Guo K, Shen F, Shen M, Ruan S
Evidence-based complementary and alternative medicine : eCAM 2019;2019:1431726
Evidence-based complementary and alternative medicine : eCAM 2019;2019:1431726
RAD51 is a potential marker for prognosis and regulates cell proliferation in pancreatic cancer.
Zhang X, Ma N, Yao W, Li S, Ren Z
Cancer cell international 2019;19:356
Cancer cell international 2019;19:356
Casticin inhibits nasopharyngeal carcinoma growth by targeting phosphoinositide 3-kinase.
Liu J, Yang J, Hou Y, Zhu Z, He J, Zhao H, Ye X, Li D, Wu Z, Huang Z, Hao B, Yao K
Cancer cell international 2019;19:348
Cancer cell international 2019;19:348
SIRT6/HIF-1α axis promotes papillary thyroid cancer progression by inducing epithelial-mesenchymal transition.
Yang Z, Yu W, Huang R, Ye M, Min Z
Cancer cell international 2019;19:17
Cancer cell international 2019;19:17
TGF-β1 Induces Epithelial-Mesenchymal Transition of Chronic Sinusitis with Nasal Polyps through MicroRNA-21.
Li X, Li C, Zhu G, Yuan W, Xiao ZA
International archives of allergy and immunology 2019;179(4):304-319
International archives of allergy and immunology 2019;179(4):304-319
Anti-apoptotic effect of the Shh signaling pathway in cigarette smoke extract induced MLE 12 apoptosis.
Li J, Zong D, Chen Y, Chen P
Tobacco induced diseases 2019;17:49
Tobacco induced diseases 2019;17:49
P11 Loss-of-Function is Associated with Decreased Cell Proliferation and Neurobehavioral Disorders in Mice.
Liu G, Wang Y, Zheng W, Cheng H, Zhou R
International journal of biological sciences 2019;15(7):1383-1395
International journal of biological sciences 2019;15(7):1383-1395
Glycolytic Enzyme PKM2 Mediates Autophagic Activation to Promote Cell Survival in NPM1-Mutated Leukemia.
Wang L, Yang L, Yang Z, Tang Y, Tao Y, Zhan Q, Lei L, Jing Y, Jiang X, Jin H, Zou Q, Xian J, Zhang L
International journal of biological sciences 2019;15(4):882-894
International journal of biological sciences 2019;15(4):882-894
LncRNA SLCO4A1-AS1 predicts poor prognosis and promotes proliferation and metastasis via the EGFR/MAPK pathway in colorectal cancer.
Tang R, Chen J, Tang M, Liao Z, Zhou L, Jiang J, Hu Y, Liao Q, Xiong W, Tang Y, Nie S
International journal of biological sciences 2019;15(13):2885-2896
International journal of biological sciences 2019;15(13):2885-2896
LncRNA expression profile during autophagy and Malat1 function in macrophages.
Ma Z, Zhang J, Xu X, Qu Y, Dong H, Dang J, Huo Z, Xu G
PloS one 2019;14(8):e0221104
PloS one 2019;14(8):e0221104
NAMPT overexpression alleviates alcohol-induced hepatic steatosis in mice.
Xiong X, Yu J, Fan R, Zhang C, Xu L, Sun X, Huang Y, Wang Q, Ruan HB, Qian X
PloS one 2019;14(2):e0212523
PloS one 2019;14(2):e0212523
Porous Se@SiO2 nanocomposite promotes migration and osteogenic differentiation of rat bone marrow mesenchymal stem cell to accelerate bone fracture healing in a rat model.
Li C, Wang Q, Gu X, Kang Y, Zhang Y, Hu Y, Li T, Jin H, Deng G, Wang Q
International journal of nanomedicine 2019;14:3845-3860
International journal of nanomedicine 2019;14:3845-3860
Inhibition of COX2/PGD2-Related Autophagy Is Involved in the Mechanism of Brain Injury in T2DM Rat.
Yang Y, Chen Q, Zhao Q, Luo Y, Xu Y, Du W, Wang H, Li H, Yang L, Hu C, Zhang J, Li Y, Xia H, Chen Z, Ma J, Tian X, Yang J
Frontiers in cellular neuroscience 2019;13:68
Frontiers in cellular neuroscience 2019;13:68
Bone Mesenchymal Stem Cell-Derived Extracellular Vesicles Promote Recovery Following Spinal Cord Injury via Improvement of the Integrity of the Blood-Spinal Cord Barrier.
Lu Y, Zhou Y, Zhang R, Wen L, Wu K, Li Y, Yao Y, Duan R, Jia Y
Frontiers in neuroscience 2019;13:209
Frontiers in neuroscience 2019;13:209
CITED1 contributes to the progression of papillary thyroid carcinoma via the Wnt/β-catenin signaling pathway.
Wang Y, Huang H, Hu F, Li J, Zhang L, Pang H
OncoTargets and therapy 2019;12:6769-6777
OncoTargets and therapy 2019;12:6769-6777
GPX2 suppression of H2O2 stress regulates cervical cancer metastasis and apoptosis via activation of the β-catenin-WNT pathway.
Wang Y, Cao P, Alshwmi M, Jiang N, Xiao Z, Jiang F, Gu J, Wang X, Sun X, Li S
OncoTargets and therapy 2019;12:6639-6651
OncoTargets and therapy 2019;12:6639-6651
SIRT6 promotes the Warburg effect of papillary thyroid cancer cell BCPAP through reactive oxygen species.
Yu W, Yang Z, Huang R, Min Z, Ye M
OncoTargets and therapy 2019;12:2861-2868
OncoTargets and therapy 2019;12:2861-2868
Prognostic implications and oncogenic roles of MYBL2 protein expression in esophageal squamous-cell carcinoma.
Qin H, Li Y, Zhang H, Wang F, He H, Bai X, Li S
OncoTargets and therapy 2019;12:1917-1927
OncoTargets and therapy 2019;12:1917-1927
DHT deteriorates the progression of monocrotaline-induced pulmonary arterial hypertension: effects of endogenous and exogenous androgen.
Wen J, Wang J, Tang X, Deng S, Dai J, Li X, Cai W
American journal of translational research 2019;11(9):5752-5763
American journal of translational research 2019;11(9):5752-5763
miR-23a-5p inhibits cell proliferation and invasion in pancreatic ductal adenocarcinoma by suppressing ECM1 expression.
Huang W, Huang Y, Gu J, Zhang J, Yang J, Liu S, Xie C, Fan Y, Wang H
American journal of translational research 2019;11(5):2983-2994
American journal of translational research 2019;11(5):2983-2994
The IRE1α-XBP1 pathway function in hypoxia-induced pulmonary vascular remodeling, is upregulated by quercetin, inhibits apoptosis and partially reverses the effect of quercetin in PASMCs.
Cao X, He Y, Li X, Xu Y, Liu X
American journal of translational research 2019;11(2):641-654
American journal of translational research 2019;11(2):641-654
Rutin suppresses FNDC1 expression in bone marrow mesenchymal stem cells to inhibit postmenopausal osteoporosis.
Xiao Y, Wei R, Yuan Z, Lan X, Kuang J, Hu D, Song Y, Luo J
American journal of translational research 2019;11(10):6680-6690
American journal of translational research 2019;11(10):6680-6690
The lncRNA HOXA11-AS regulates Rab3D expression by sponging miR-125a-5p promoting metastasis of osteosarcoma.
Cao K, Fang Y, Wang H, Jiang Z, Guo L, Hu Y
Cancer management and research 2019;11:4505-4518
Cancer management and research 2019;11:4505-4518
High expression of SMARCE1 predicts poor prognosis and promotes cell growth and metastasis in gastric cancer.
Liu H, Zhao YR, Chen B, Ge Z, Huang JS
Cancer management and research 2019;11:3493-3509
Cancer management and research 2019;11:3493-3509
Catalpol Exerts a Neuroprotective Effect in the MPTP Mouse Model of Parkinson's Disease.
Wang LY, Yu X, Li XX, Zhao YN, Wang CY, Wang ZY, He ZY
Frontiers in aging neuroscience 2019;11:316
Frontiers in aging neuroscience 2019;11:316
MARCH5 overexpression contributes to tumor growth and metastasis and associates with poor survival in breast cancer.
Tang H, Peng S, Dong Y, Yang X, Yang P, Yang L, Yang B, Bao G
Cancer management and research 2019;11:201-215
Cancer management and research 2019;11:201-215
AAV-Mig-6 Increase the Efficacy of TAE in VX2 Rabbit Model, Is Associated With JNK Mediated Autophagy.
Li Z, Tian Y, Qu L, Mao J, Zhong H
Journal of Cancer 2019;10(4):1060-1069
Journal of Cancer 2019;10(4):1060-1069
Up-regulation of EMT-related gene VCAN by NPM1 mutant-driven TGF-β/cPML signalling promotes leukemia cell invasion.
Yang L, Wang L, Yang Z, Jin H, Zou Q, Zhan Q, Tang Y, Tao Y, Lei L, Jing Y, Jiang X, Zhang L
Journal of Cancer 2019;10(26):6570-6583
Journal of Cancer 2019;10(26):6570-6583
SIRT5 Promotes Hepatocellular Carcinoma Progression by Regulating Mitochondrial Apoptosis.
Zhang R, Wang C, Tian Y, Yao Y, Mao J, Wang H, Li Z, Xu Y, Ye M, Wang L
Journal of Cancer 2019;10(16):3871-3882
Journal of Cancer 2019;10(16):3871-3882
Involvement of Actin-Regulating Factor Cofilin in the Inclusion Body Formation and RNA Synthesis of Human Parainfluenza Virus Type 3 via Interaction With the Nucleoprotein.
Li Y, Zhang C, Lu N, Deng X, Zang G, Zhang S, Tang H, Zhang G
Frontiers in microbiology 2019;10:95
Frontiers in microbiology 2019;10:95
Naringenin Produces Neuroprotection Against LPS-Induced Dopamine Neurotoxicity via the Inhibition of Microglial NLRP3 Inflammasome Activation.
Chen C, Wei YZ, He XM, Li DD, Wang GQ, Li JJ, Zhang F
Frontiers in immunology 2019;10:936
Frontiers in immunology 2019;10:936
miR-181b-5p May Regulate Muscle Growth in Tilapia by Targeting Myostatin b.
Zhao Z, Yu X, Jia J, Yang G, Sun C, Li W
Frontiers in endocrinology 2019;10:812
Frontiers in endocrinology 2019;10:812
TLR4/NF-κB Signaling Induces GSDMD-Related Pyroptosis in Tubular Cells in Diabetic Kidney Disease.
Wang Y, Zhu X, Yuan S, Wen S, Liu X, Wang C, Qu Z, Li J, Liu H, Sun L, Liu F
Frontiers in endocrinology 2019;10:603
Frontiers in endocrinology 2019;10:603
The Wnt/β-Catenin/LEF1 Pathway Promotes Cell Proliferation at Least in Part Through Direct Upregulation of miR-17-92 Cluster.
Mu F, Huang J, Xing T, Jing Y, Cui T, Guo Y, Yan X, Li H, Wang N
Frontiers in genetics 2019;10:525
Frontiers in genetics 2019;10:525
Combined melatonin and poricoic acid A inhibits renal fibrosis through modulating the interaction of Smad3 and β-catenin pathway in AKI-to-CKD continuum.
Chen DQ, Cao G, Zhao H, Chen L, Yang T, Wang M, Vaziri ND, Guo Y, Zhao YY
Therapeutic advances in chronic disease 2019;10:2040622319869116
Therapeutic advances in chronic disease 2019;10:2040622319869116
Protective Effects of 18β-Glycyrrhetinic Acid on Monocrotaline-Induced Pulmonary Arterial Hypertension in Rats.
Zhang M, Chang Z, Zhao F, Zhang P, Hao YJ, Yan L, Liu N, Wang JL, Bo L, Ma P, Zhou W, Ma X, Xu QB, Zhou R
Frontiers in pharmacology 2019;10:13
Frontiers in pharmacology 2019;10:13
Downregulation of Wnt3 Suppresses Colorectal Cancer Development Through Inhibiting Cell Proliferation and Migration.
Nie X, Xia F, Liu Y, Zhou Y, Ye W, Hean P, Meng J, Liu H, Liu L, Wen J, Ren X, Chen WD, Wang YD
Frontiers in pharmacology 2019;10:1110
Frontiers in pharmacology 2019;10:1110
The Therapeutic Effects of Treadmill Exercise on Osteoarthritis in Rats by Inhibiting the HDAC3/NF-KappaB Pathway in vivo and in vitro.
Zhang H, Ji L, Yang Y, Wei Y, Zhang X, Gang Y, Lu J, Bai L
Frontiers in physiology 2019;10:1060
Frontiers in physiology 2019;10:1060
Protective mechanism of Taxifolin for chlorpyrifos neurotoxicity in BV2 cells.
Zhang C, Zhan J, Zhao M, Dai H, Deng Y, Zhou W, Zhao L
Neurotoxicology 2019 Sep;74:74-80
Neurotoxicology 2019 Sep;74:74-80
Time-dependent C5a and C5aR expression in dental pulp cells following stimulation with LTA and LPS.
Liu M, Mu H, Peng W, Zhao L, Hu W, Jiang Z, Gao L, Cao X, Li N, Han J
International journal of molecular medicine 2019 Sep;44(3):823-834
International journal of molecular medicine 2019 Sep;44(3):823-834
Fluorene-9-bisphenol inhibits epithelial-mesenchymal transition of human endometrial cancer Ishikawa cells by repressing TGF-β signaling pathway.
Wang L, Zhuang T, Li F, Wei W
Environmental science and pollution research international 2019 Sep;26(26):27407-27413
Environmental science and pollution research international 2019 Sep;26(26):27407-27413
Hydrogen inhalation protects hypoxic-ischemic brain damage by attenuating inflammation and apoptosis in neonatal rats.
Wu G, Chen Z, Wang P, Zhao M, Fujino M, Zhang C, Zhou W, Hirano SI, Li XK, Zhao L
Experimental biology and medicine (Maywood, N.J.) 2019 Sep;244(12):1017-1027
Experimental biology and medicine (Maywood, N.J.) 2019 Sep;244(12):1017-1027
Resveratrol inhibits the invasion and metastasis of colon cancer through reversal of epithelial‑ mesenchymal transition via the AKT/GSK‑3β/Snail signaling pathway.
Yuan L, Zhou M, Huang D, Wasan HS, Zhang K, Sun L, Huang H, Ma S, Shen M, Ruan S
Molecular medicine reports 2019 Sep;20(3):2783-2795
Molecular medicine reports 2019 Sep;20(3):2783-2795
TAK242 suppresses the TLR4 signaling pathway and ameliorates DCD liver IRI in rats.
Zhong X, Xiao Q, Liu Z, Wang W, Lai CH, Yang W, Yue P, Ye Q, Xiao J
Molecular medicine reports 2019 Sep;20(3):2101-2110
Molecular medicine reports 2019 Sep;20(3):2101-2110
Mechanism Underlying the Protective Effect of Selenium on NO-Induced Oxidative Damage in Bovine Mammary Epithelial Cells.
Guo Y, Guo X, Yan S, Zhang B, Shi B
Biological trace element research 2019 Sep;191(1):104-114
Biological trace element research 2019 Sep;191(1):104-114
Association between CIRP expression and hypoxic-ischemic brain injury in neonatal rats.
Chen L, Tian Q, Wang W
Experimental and therapeutic medicine 2019 Sep;18(3):1515-1520
Experimental and therapeutic medicine 2019 Sep;18(3):1515-1520
REG4 is an indicator for KRAS mutant lung adenocarcinoma with TTF-1 low expression.
Sun S, Hu Z, Huang S, Ye X, Wang J, Chang J, Wu X, Wang Q, Zhang L, Hu X, Yu H
Journal of cancer research and clinical oncology 2019 Sep;145(9):2273-2283
Journal of cancer research and clinical oncology 2019 Sep;145(9):2273-2283
Novel diterpenoid-type activators of the Keap1/Nrf2/ARE signaling pathway and their regulation of redox homeostasis.
Li AL, Shen T, Wang T, Zhou MX, Wang B, Song JT, Zhang PL, Wang XL, Ren DM, Lou HX, Wang XN
Free radical biology & medicine 2019 Sep;141:21-33
Free radical biology & medicine 2019 Sep;141:21-33
Multi-walled carbon nanotubes (MWCNTs) promoted lipid accumulation in THP-1 macrophages through modulation of endoplasmic reticulum (ER) stress.
Long J, Ma W, Yu Z, Liu H, Cao Y
Nanotoxicology 2019 Sep;13(7):938-951
Nanotoxicology 2019 Sep;13(7):938-951
Targeting Exosomal EBV-LMP1 Transfer and miR-203 Expression via the NF-κB Pathway: The Therapeutic Role of Aspirin in NPC.
Zuo L, Xie Y, Tang J, Xin S, Liu L, Zhang S, Yan Q, Zhu F, Lu J
Molecular therapy. Nucleic acids 2019 Sep 6;17:175-184
Molecular therapy. Nucleic acids 2019 Sep 6;17:175-184
Enhancing the retrograde axonal transport by curcumin promotes autophagic flux in N2a/APP695swe cells.
Liang J, Zhou F, Xiong X, Zhang X, Li S, Li X, Gao M, Li Y
Aging 2019 Sep 6;11(17):7036-7050
Aging 2019 Sep 6;11(17):7036-7050
ROS/KRAS/AMPK Signaling Contributes to Gemcitabine-Induced Stem-like Cell Properties in Pancreatic Cancer.
Zhao H, Wu S, Li H, Duan Q, Zhang Z, Shen Q, Wang C, Yin T
Molecular therapy oncolytics 2019 Sep 27;14:299-312
Molecular therapy oncolytics 2019 Sep 27;14:299-312
Establishment of an Experimental Intracerebral Haemorrhage Model for Mass Effect Research using a Thermo-sensitive Hydrogel.
Gong Y, Gong Y, Hou Z, Guo T, Deng J, Hao S, Wang B
Scientific reports 2019 Sep 25;9(1):13838
Scientific reports 2019 Sep 25;9(1):13838
Protective effects of 18β-glycyrrhetinic acid on pulmonary arterial hypertension via regulation of Rho A/Rho kinsase pathway.
Zhang M, Chang Z, Zhang P, Jing Z, Yan L, Feng J, Hu Z, Xu Q, Zhou W, Ma P, Hao Y, Zhou R
Chemico-biological interactions 2019 Sep 25;311:108749
Chemico-biological interactions 2019 Sep 25;311:108749
OPA1 overexpression ameliorates mitochondrial cristae remodeling, mitochondrial dysfunction, and neuronal apoptosis in prion diseases.
Wu W, Zhao D, Shah SZA, Zhang X, Lai M, Yang D, Wu X, Guan Z, Li J, Zhao H, Li W, Gao H, Zhou X, Qiao J, Yang L
Cell death & disease 2019 Sep 24;10(10):710
Cell death & disease 2019 Sep 24;10(10):710
Structural Characterization and Antioxidant Activity of Polysaccharides from Athyrium multidentatum (Doll.) Ching in d-Galactose-Induced Aging Mice via PI3K/AKT Pathway.
Jing L, Jiang JR, Liu DM, Sheng JW, Zhang WF, Li ZJ, Wei LY
Molecules (Basel, Switzerland) 2019 Sep 16;24(18)
Molecules (Basel, Switzerland) 2019 Sep 16;24(18)
Long Noncoding RNA FAM225A Promotes Nasopharyngeal Carcinoma Tumorigenesis and Metastasis by Acting as ceRNA to Sponge miR-590-3p/miR-1275 and Upregulate ITGB3.
Zheng ZQ, Li ZX, Zhou GQ, Lin L, Zhang LL, Lv JW, Huang XD, Liu RQ, Chen F, He XJ, Kou J, Zhang J, Wen X, Li YQ, Ma J, Liu N, Sun Y
Cancer research 2019 Sep 15;79(18):4612-4626
Cancer research 2019 Sep 15;79(18):4612-4626
Age-Associated Dopaminergic Neuron Loss and Midbrain Glia Cell Phenotypic Polarization.
Wang G, Zhou Y, Wang Y, Li D, Liu J, Zhang F
Neuroscience 2019 Sep 1;415:89-96
Neuroscience 2019 Sep 1;415:89-96
Antinociceptive effect of isoorientin against neuropathic pain induced by the chronic constriction injury of the sciatic nerve in mice.
Zhang G, Liu N, Zhu C, Ma L, Yang J, Du J, Zhang W, Sun T, Niu J, Yu J
International immunopharmacology 2019 Oct;75:105753
International immunopharmacology 2019 Oct;75:105753
Macrophage migration inhibitory factor promotes the invasion and metastasis of oral squamous cell carcinoma through matrix metalloprotein-2/9.
Wang SS, Zheng M, Pang X, Zhang M, Yu XH, Wu JB, Gao XL, Wu JS, Yang X, Tang YJ, Tang YL, Liang XH
Molecular carcinogenesis 2019 Oct;58(10):1809-1821
Molecular carcinogenesis 2019 Oct;58(10):1809-1821
Bromodomain inhibitor jq1 induces cell cycle arrest and apoptosis of glioma stem cells through the VEGF/PI3K/AKT signaling pathway.
Wen N, Guo B, Zheng H, Xu L, Liang H, Wang Q, Wang D, Chen X, Zhang S, Li Y, Zhang L
International journal of oncology 2019 Oct;55(4):879-895
International journal of oncology 2019 Oct;55(4):879-895
Paip1 Indicated Poor Prognosis in Cervical Cancer and Promoted Cervical Carcinogenesis.
Li N, Piao J, Wang X, Kim KY, Bae JY, Ren X, Lin Z
Cancer research and treatment 2019 Oct;51(4):1653-1665
Cancer research and treatment 2019 Oct;51(4):1653-1665
Babao Dan induces gastric cancer cell apoptosis via regulating MAPK and NF-κB signaling pathways.
Shang H, Cao Z, Zhao J, Guan J, Liu J, Peng J, Chen Y, Joseph Sferra T, Sankararaman S, Lin J
The Journal of international medical research 2019 Oct;47(10):5106-5119
The Journal of international medical research 2019 Oct;47(10):5106-5119
Downregulation of nicotinamide N-methyltransferase inhibits migration and epithelial-mesenchymal transition of esophageal squamous cell carcinoma via Wnt/β-catenin pathway.
Cui Y, Zhang L, Wang W, Ma S, Liu H, Zang X, Zhang Y, Guan F
Molecular and cellular biochemistry 2019 Oct;460(1-2):93-103
Molecular and cellular biochemistry 2019 Oct;460(1-2):93-103
Apatinib inhibits glycolysis by suppressing the VEGFR2/AKT1/SOX5/GLUT4 signaling pathway in ovarian cancer cells.
Chen L, Cheng X, Tu W, Qi Z, Li H, Liu F, Yang Y, Zhang Z, Wang Z
Cellular oncology (Dordrecht) 2019 Oct;42(5):679-690
Cellular oncology (Dordrecht) 2019 Oct;42(5):679-690
Propofol attenuates TNF-α-induced MMP-9 expression in human cerebral microvascular endothelial cells by inhibiting Ca2+/CAMK II/ERK/NF-κB signaling pathway.
Ding XW, Sun X, Shen XF, Lu Y, Wang JQ, Sun ZR, Miao CH, Chen JW
Acta pharmacologica Sinica 2019 Oct;40(10):1303-1313
Acta pharmacologica Sinica 2019 Oct;40(10):1303-1313
A novel long noncoding RNA PGC1β-OT1 regulates adipocyte and osteoblast differentiation through antagonizing miR-148a-3p.
Yuan H, Xu X, Feng X, Zhu E, Zhou J, Wang G, Tian L, Wang B
Cell death and differentiation 2019 Oct;26(10):2029-2045
Cell death and differentiation 2019 Oct;26(10):2029-2045
Whole-Exome Sequencing Analysis Identified Novel Mutations in the TSPAN12 Gene in Chinese Families with Familial Exudative Vitreoretinopathy.
Yuan Y, Xu H, Zhang S, Zhang X, Zhang L, Yang Z
Genetic testing and molecular biomarkers 2019 Oct;23(10):722-727
Genetic testing and molecular biomarkers 2019 Oct;23(10):722-727
Turnover of bile acids in liver, serum and caecal content by high-fat diet feeding affects hepatic steatosis in rats.
Tang Y, Zhang J, Li J, Lei X, Xu D, Wang Y, Li C, Li X, Mao Y
Biochimica et biophysica acta. Molecular and cell biology of lipids 2019 Oct;1864(10):1293-1304
Biochimica et biophysica acta. Molecular and cell biology of lipids 2019 Oct;1864(10):1293-1304
CX-F9, a novel RSK2 inhibitor, suppresses cutaneous melanoma cells proliferation and metastasis through regulating autophagy.
Zhang X, Cai L, Zhao S, Long J, Li J, Wu L, Su J, Zhang J, Tao J, Zhou J, Chen X, Peng C
Biochemical pharmacology 2019 Oct;168:14-25
Biochemical pharmacology 2019 Oct;168:14-25
Novel ADAM-17 inhibitor ZLDI-8 inhibits the proliferation and metastasis of chemo-resistant non-small-cell lung cancer by reversing Notch and epithelial mesenchymal transition in vitro and in vivo.
Lu HY, Zu YX, Jiang XW, Sun XT, Liu TY, Li RL, Wu Q, Zhang YS, Zhao QC
Pharmacological research 2019 Oct;148:104406
Pharmacological research 2019 Oct;148:104406
RNA-Seq analysis of potential lncRNAs and genes for the anti-renal fibrotic effect of norcantharidin.
Xiao H, Liao Y, Tang C, Xiao Z, Luo H, Li J, Liu H, Sun L, Zeng D, Li Y
Journal of cellular biochemistry 2019 Oct;120(10):17354-17367
Journal of cellular biochemistry 2019 Oct;120(10):17354-17367
Neuroprotective effect of Vanillin on hypoxic-ischemic brain damage in neonatal rats.
Lan XB, Wang Q, Yang JM, Ma L, Zhang WJ, Zheng P, Sun T, Niu JG, Liu N, Yu JQ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109196
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109196
Dehydroepiandrosterone alleviates E. Coli O157:H7-induced inflammation by preventing the activation of p38 MAPK and NF-κB pathways in mice peritoneal macrophages.
Zhao J, Cao J, Yu L, Ma H
Molecular immunology 2019 Oct;114:114-122
Molecular immunology 2019 Oct;114:114-122
Oncogenic ADAM28 induces gemcitabine resistance and predicts a poor prognosis in pancreatic cancer.
Wei L, Wen JY, Chen J, Ma XK, Wu DH, Chen ZH, Huang JL
World journal of gastroenterology 2019 Oct 7;25(37):5590-5603
World journal of gastroenterology 2019 Oct 7;25(37):5590-5603
Adipose tissue-derived omentin-1 attenuates arterial calcification via AMPK/Akt signaling pathway.
Xu F, Li FX, Lin X, Zhong JY, Wu F, Shan SK, Tan CM, Yuan LQ, Liao XB
Aging 2019 Oct 25;11(20):8760-8776
Aging 2019 Oct 25;11(20):8760-8776
ROS-mediated inactivation of the PI3K/AKT pathway is involved in the antigastric cancer effects of thioredoxin reductase-1 inhibitor chaetocin.
Wen C, Wang H, Wu X, He L, Zhou Q, Wang F, Chen S, Huang L, Chen J, Wang H, Ye W, Li W, Yang X, Liu H, Peng J
Cell death & disease 2019 Oct 24;10(11):809
Cell death & disease 2019 Oct 24;10(11):809
Fractionated irradiation of right thorax induces abscopal damage on testes leading to decline in fertility.
Zhang J, Yao D, Song Y, Pan Y, Zhu L, Bai Y, Xu Y, Zhang J, Shao C
Scientific reports 2019 Oct 23;9(1):15221
Scientific reports 2019 Oct 23;9(1):15221
HIF-1α contributes to Ang II-induced inflammatory cytokine production in podocytes.
Huang H, Fan Y, Gao Z, Wang W, Shao N, Zhang L, Yang Y, Zhu W, Chen Z, Hu J, Ding G
BMC pharmacology & toxicology 2019 Oct 17;20(1):59
BMC pharmacology & toxicology 2019 Oct 17;20(1):59
The interference of DEHP in precocious puberty of females mediated by the hypothalamic IGF-1/PI3K/Akt/mTOR signaling pathway.
Shao P, Wang Y, Zhang M, Wen X, Zhang J, Xu Z, Hu M, Jiang J, Liu T
Ecotoxicology and environmental safety 2019 Oct 15;181:362-369
Ecotoxicology and environmental safety 2019 Oct 15;181:362-369
Young Blood Rescues the Cognition of Alzheimer's Model Mice by Restoring the Hippocampal Cholinergic Circuit.
Xia E, Xu F, Hu C, Kumal JPP, Tang X, Mao D, Li Y, Wu D, Zhang R, Wu S, Sun L
Neuroscience 2019 Oct 1;417:57-69
Neuroscience 2019 Oct 1;417:57-69
PPAR-δ of orange-spotted grouper exerts antiviral activity against fish virus and regulates interferon signaling and inflammatory factors.
Wang Y, Yu Y, Wang Q, Wei S, Wang S, Qin Q, Yang M
Fish & shellfish immunology 2019 Nov;94:38-49
Fish & shellfish immunology 2019 Nov;94:38-49
Piperine as a neuroprotective functional component in rats with cerebral ischemic injury.
Hua S, Liu J, Zhang Y, Li J, Zhang X, Dong L, Zhao Y, Fu X
Food science & nutrition 2019 Nov;7(11):3443-3451
Food science & nutrition 2019 Nov;7(11):3443-3451
Niban protein regulates apoptosis in HK-2 cells via caspase-dependent pathway.
Tang S, Wang J, Liu J, Huang Y, Zhou Y, Yang S, Zhang W, Yang M, Zhang H
Renal failure 2019 Nov;41(1):455-466
Renal failure 2019 Nov;41(1):455-466
Cadmium regulates von Willebrand factor and occludin expression in glomerular endothelial cells of mice in a TNF-α-dependent manner.
Sun Z, Xie Q, Pan J, Niu N
Renal failure 2019 Nov;41(1):354-362
Renal failure 2019 Nov;41(1):354-362
Wnt1 silencing enhances neurotoxicity induced by paraquat and maneb in SH-SY5Y cells.
Huang C, Ma J, Li BX, Sun Y
Experimental and therapeutic medicine 2019 Nov;18(5):3643-3649
Experimental and therapeutic medicine 2019 Nov;18(5):3643-3649
Propionate relieves pentylenetetrazol-induced seizures, consequent mitochondrial disruption, neuron necrosis and neurological deficits in mice.
Cheng Y, Mai Q, Zeng X, Wang H, Xiao Y, Tang L, Li J, Zhang Y, Ding H
Biochemical pharmacology 2019 Nov;169:113607
Biochemical pharmacology 2019 Nov;169:113607
Iron dysregulation in vascular dementia: Focused on the AMPK/autophagy pathway.
Huo T, Jia Y, Yin C, Luo X, Zhao J, Wang Z, Lv P
Brain research bulletin 2019 Nov;153:305-313
Brain research bulletin 2019 Nov;153:305-313
Identification of predictors of drug sensitivity using patient-derived models of esophageal squamous cell carcinoma.
Su D, Zhang D, Jin J, Ying L, Han M, Chen K, Li B, Wu J, Xie Z, Zhang F, Lin Y, Cheng G, Li JY, Huang M, Wang J, Wang K, Zhang J, Li F, Xiong L, Futreal A, Mao W
Nature communications 2019 Nov 7;10(1):5076
Nature communications 2019 Nov 7;10(1):5076
Hypertension-associated mitochondrial DNA 4401A>G mutation caused the aberrant processing of tRNAMet, all 8 tRNAs and ND6 mRNA in the light-strand transcript.
Zhao X, Cui L, Xiao Y, Mao Q, Aishanjiang M, Kong W, Liu Y, Chen H, Hong F, Jia Z, Wang M, Jiang P, Guan MX
Nucleic acids research 2019 Nov 4;47(19):10340-10356
Nucleic acids research 2019 Nov 4;47(19):10340-10356
Dexmedetomidine inhibits neuronal apoptosis by inducing Sigma-1 receptor signaling in cerebral ischemia-reperfusion injury.
Zhai M, Liu C, Li Y, Zhang P, Yu Z, Zhu H, Zhang L, Zhang Q, Wang J, Wang J
Aging 2019 Nov 4;11(21):9556-9568
Aging 2019 Nov 4;11(21):9556-9568
Oroxin B Induces Apoptosis by Down-Regulating MicroRNA-221 Resulting in the Inactivation of the PTEN/PI3K/AKT Pathway in Liver Cancer.
Li N, Men W, Zheng Y, Wang H, Meng X
Molecules (Basel, Switzerland) 2019 Nov 30;24(23)
Molecules (Basel, Switzerland) 2019 Nov 30;24(23)
PP2Ac Modulates AMPK-Mediated Induction of Autophagy in Mycobacterium bovis-Infected Macrophages.
Hussain T, Zhao D, Shah SZA, Sabir N, Wang J, Liao Y, Song Y, Hussain Mangi M, Yao J, Dong H, Yang L, Zhou X
International journal of molecular sciences 2019 Nov 29;20(23)
International journal of molecular sciences 2019 Nov 29;20(23)
Protrudin modulates seizure activity through GABAA receptor regulation.
Lu X, Yang Y, Zhou R, Li Y, Yang Y, Wang X
Cell death & disease 2019 Nov 27;10(12):897
Cell death & disease 2019 Nov 27;10(12):897
Folic acid delays age-related cognitive decline in senescence-accelerated mouse prone 8: alleviating telomere attrition as a potential mechanism.
Lv X, Wang X, Wang Y, Zhou D, Li W, Wilson JX, Chang H, Huang G
Aging 2019 Nov 22;11(22):10356-10373
Aging 2019 Nov 22;11(22):10356-10373
Inhibition of Bcl-2 Synergistically Enhances the Antileukemic Activity of Midostaurin and Gilteritinib in Preclinical Models of FLT3-Mutated Acute Myeloid Leukemia.
Ma J, Zhao S, Qiao X, Knight T, Edwards H, Polin L, Kushner J, Dzinic SH, White K, Wang G, Zhao L, Lin H, Wang Y, Taub JW, Ge Y
Clinical cancer research : an official journal of the American Association for Cancer Research 2019 Nov 15;25(22):6815-6826
Clinical cancer research : an official journal of the American Association for Cancer Research 2019 Nov 15;25(22):6815-6826
Chitosan Ameliorates DSS-Induced Ulcerative Colitis Mice by Enhancing Intestinal Barrier Function and Improving Microflora.
Wang J, Zhang C, Guo C, Li X
International journal of molecular sciences 2019 Nov 15;20(22)
International journal of molecular sciences 2019 Nov 15;20(22)
Circ-ASH2L promotes tumor progression by sponging miR-34a to regulate Notch1 in pancreatic ductal adenocarcinoma.
Chen Y, Li Z, Zhang M, Wang B, Ye J, Zhang Y, Tang D, Ma D, Jin W, Li X, Wang S
Journal of experimental & clinical cancer research : CR 2019 Nov 12;38(1):466
Journal of experimental & clinical cancer research : CR 2019 Nov 12;38(1):466
Protective effects of Clec11a in islets against lipotoxicity via modulation of proliferation and lipid metabolism in mice.
Shi R, Hu J, Li W, Wang Z, Pan Y, Bai M, Mao W, Wang X, Zhong M, Yuan Y, Lau J, Sun Z, Zhao S
Experimental cell research 2019 Nov 1;384(1):111613
Experimental cell research 2019 Nov 1;384(1):111613
Elevated Levels of Arachidonic Acid Metabolites in Follicular Fluid of PCOS Patients.
Li S, Qi J, Tao Y, Zhu Q, Huang R, Liao Y, Yue J, Liu W, Zhao H, Yin H, Sun Y
Reproduction (Cambridge, England) 2019 Nov 1;
Reproduction (Cambridge, England) 2019 Nov 1;
Melatonin protects against COPD by attenuating apoptosis and endoplasmic reticulum stress via upregulating SIRT1 expression in rats.
He B, Zhang W, Qiao J, Peng Z, Chai X
Canadian journal of physiology and pharmacology 2019 May;97(5):386-391
Canadian journal of physiology and pharmacology 2019 May;97(5):386-391
Functional analysis of the CXCR1a gene response to SGIV viral infection in grouper.
Wang Q, Yang M, Li C, Wang S, Wang Y, Lin F, Zheng L, Yu Y, Qin Q
Fish & shellfish immunology 2019 May;88:217-224
Fish & shellfish immunology 2019 May;88:217-224
A novel tumor suppressor SPINK5 targets Wnt/β-catenin signaling pathway in esophageal cancer.
Wang Q, Lv Q, Bian H, Yang L, Guo KL, Ye SS, Dong XF, Tao LL
Cancer medicine 2019 May;8(5):2360-2371
Cancer medicine 2019 May;8(5):2360-2371
Microglial LOX-1/MAPKs/NF-κB positive loop promotes the vicious cycle of neuroinflammation and neural injury.
Ge X, Zhang DM, Li MM, Zhang Y, Zhu XY, Zhou Y, Peng X, Shen AG
International immunopharmacology 2019 May;70:187-200
International immunopharmacology 2019 May;70:187-200
Activation of Nrf2 signaling by Icariin protects against 6-OHDA-induced neurotoxicity.
Zhu L, Li D, Chen C, Wang G, Shi J, Zhang F
Biotechnology and applied biochemistry 2019 May;66(3):465-471
Biotechnology and applied biochemistry 2019 May;66(3):465-471
Circular RNA cMras inhibits lung adenocarcinoma progression via modulating miR-567/PTPRG regulatory pathway.
Yu C, Tian F, Liu J, Su M, Wu M, Zhu X, Qian W
Cell proliferation 2019 May;52(3):e12610
Cell proliferation 2019 May;52(3):e12610
Eutopic endometrium from patients with endometriosis modulates the expression of CD36 and SIRP-α in peritoneal macrophages.
Xie Q, He H, Wu YH, Zou LJ, She XL, Xia XM, Wu XQ
The journal of obstetrics and gynaecology research 2019 May;45(5):1045-1057
The journal of obstetrics and gynaecology research 2019 May;45(5):1045-1057
Induced Pluripotent Stem Cells Regulate Triggering Receptor Expressed on Myeloid Cell-1 Expression and the p38 Mitogen-Activated Protein Kinase Pathway in Endotoxin-Induced Acute Lung Injury.
Su VY, Yang KY, Chiou SH, Chen NJ, Mo MH, Lin CS, Wang CT
Stem cells (Dayton, Ohio) 2019 May;37(5):631-639
Stem cells (Dayton, Ohio) 2019 May;37(5):631-639
HepaCAM Regulates Warburg Effect of Renal Cell Carcinoma via HIF-1α/NF-κB Signaling Pathway.
Fan Y, Ou L, Fan J, Li L, Wu X, Luo C, Gao Y, Niu L
Urology 2019 May;127:61-67
Urology 2019 May;127:61-67
Kallikrein 12 Regulates Innate Resistance of Murine Macrophages against Mycobacterium bovis Infection by Modulating Autophagy and Apoptosis.
Sabir N, Hussain T, Liao Y, Wang J, Song Y, Shahid M, Cheng G, Mangi MH, Yao J, Yang L, Zhao D, Zhou X
Cells 2019 May 5;8(5)
Cells 2019 May 5;8(5)
Predictable chronic mild stress promotes recovery from LPS-induced depression.
Dang R, Guo YY, Zhang K, Jiang P, Zhao MG
Molecular brain 2019 May 3;12(1):42
Molecular brain 2019 May 3;12(1):42
HMGB1 contributes to SASH1 methylation to attenuate astrocyte adhesion.
Wu R, Yan Y, Ma C, Chen H, Dong Z, Wang Y, Liu Y, Liu M, Yang L
Cell death & disease 2019 May 28;10(6):417
Cell death & disease 2019 May 28;10(6):417
Nilotinib: A Tyrosine Kinase Inhibitor Mediates Resistance to Intracellular Mycobacterium Via Regulating Autophagy.
Hussain T, Zhao D, Shah SZA, Sabir N, Wang J, Liao Y, Song Y, Dong H, Hussain Mangi M, Ni J, Yang L, Zhou X
Cells 2019 May 26;8(5)
Cells 2019 May 26;8(5)
Glucose metabolic alterations in hippocampus of diabetes mellitus rats and the regulation of aerobic exercise.
Li J, Liu B, Cai M, Lin X, Lou S
Behavioural brain research 2019 May 17;364:447-456
Behavioural brain research 2019 May 17;364:447-456
Efficient Production of Human Norovirus-Specific IgY in Egg Yolks by Vaccination of Hens with a Recombinant Vesicular Stomatitis Virus Expressing VP1 Protein.
Zhu Y, Ma Y, Lu M, Zhang Y, Li A, Liang X, Li J
Viruses 2019 May 16;11(5)
Viruses 2019 May 16;11(5)
Neuroprotective Effect of Swertiamain on Cerebral Ischemia/Reperfusion Injury by Inducing the Nrf2 Protective Pathway.
Wang H, Wei W, Lan X, Liu N, Li Y, Ma H, Sun T, Peng X, Zhuang C, Yu J
ACS chemical neuroscience 2019 May 15;10(5):2276-2286
ACS chemical neuroscience 2019 May 15;10(5):2276-2286
Role of OXCT1 in ovine adipose and preadipocyte differentiation.
Zeng J, Zhou SW, Zhao J, Jin MH, Kang DJ, Yang YX, Wang XL, Chen YL
Biochemical and biophysical research communications 2019 May 14;512(4):779-785
Biochemical and biophysical research communications 2019 May 14;512(4):779-785
Quantitative proteomic profiling of tumor-associated vascular endothelial cells in colorectal cancer.
Wang G, Yang Q, Li M, Zhang Y, Cai Y, Liang X, Fu Y, Xiao Z, Zhou M, Xie Z, Huang H, Huang Y, Chen Y, He Q, Peng F, Chen Z
Biology open 2019 May 13;8(5)
Biology open 2019 May 13;8(5)
Repurposing of omeprazole for oligodendrocyte differentiation and remyelination.
Zhu K, Sun J, Kang Z, Zou Z, Wu X, Wang Y, Wu G, Harris RA, Wang J
Brain research 2019 May 1;1710:33-42
Brain research 2019 May 1;1710:33-42
Hepatoprotective effects and structure-activity relationship of five flavonoids against lipopolysaccharide/d-galactosamine induced acute liver failure in mice.
He Y, Xia Z, Yu D, Wang J, Jin L, Huang D, Ye X, Li X, Zhang B
International immunopharmacology 2019 Mar;68:171-178
International immunopharmacology 2019 Mar;68:171-178
NS38 is required for aquareovirus replication via interaction with viral core proteins and host eIF3A.
Zhang J, Guo H, Zhang F, Chen Q, Chang M, Fang Q
Virology 2019 Mar;529:216-225
Virology 2019 Mar;529:216-225
CSE1L participates in regulating cell mitosis in human seminoma.
Liu C, Wei J, Xu K, Sun X, Zhang H, Xiong C
Cell proliferation 2019 Mar;52(2):e12549
Cell proliferation 2019 Mar;52(2):e12549
The endogenous retrovirus-derived long noncoding RNA TROJAN promotes triple-negative breast cancer progression via ZMYND8 degradation.
Jin X, Xu XE, Jiang YZ, Liu YR, Sun W, Guo YJ, Ren YX, Zuo WJ, Hu X, Huang SL, Shen HJ, Lan F, He YF, Hu GH, Di GH, He XH, Li DQ, Liu S, Yu KD, Shao ZM
Science advances 2019 Mar;5(3):eaat9820
Science advances 2019 Mar;5(3):eaat9820
Regulation of Neurotransmitter Release by Amyloid Precursor Protein Through Synapsin Phosphorylation.
Liu A, Zhang Y, Han L, He G, Xie W, Zhou Z, Jia Z
Neurochemical research 2019 Mar;44(3):683-691
Neurochemical research 2019 Mar;44(3):683-691
LncRNA EPB41L4A-AS1 regulates glycolysis and glutaminolysis by mediating nucleolar translocation of HDAC2.
Liao M, Liao W, Xu N, Li B, Liu F, Zhang S, Wang Y, Wang S, Zhu Y, Chen D, Xie W, Jiang Y, Cao L, Yang BB, Zhang Y
EBioMedicine 2019 Mar;41:200-213
EBioMedicine 2019 Mar;41:200-213
The selective HDAC6 inhibitor Nexturastat A induces apoptosis, overcomes drug resistance and inhibits tumor growth in multiple myeloma.
Sun X, Xie Y, Sun X, Yao Y, Li H, Li Z, Yao R, Xu K
Bioscience reports 2019 Mar 29;39(3)
Bioscience reports 2019 Mar 29;39(3)
iTRAQ-based quantitative proteomics reveals the neuroprotection of rhubarb in experimental intracerebral hemorrhage.
Liu T, Zhou J, Cui H, Li P, Luo J, Li T, He F, Wang Y, Tang T
Journal of ethnopharmacology 2019 Mar 25;232:244-254
Journal of ethnopharmacology 2019 Mar 25;232:244-254
MicroRNA-596 acts as a tumor suppressor in gastric cancer and is upregulated by promotor demethylation.
Zhang Z, Dai DQ
World journal of gastroenterology 2019 Mar 14;25(10):1224-1237
World journal of gastroenterology 2019 Mar 14;25(10):1224-1237
Hypoxic BMSC-derived exosomal miRNAs promote metastasis of lung cancer cells via STAT3-induced EMT.
Zhang X, Sai B, Wang F, Wang L, Wang Y, Zheng L, Li G, Tang J, Xiang J
Molecular cancer 2019 Mar 13;18(1):40
Molecular cancer 2019 Mar 13;18(1):40
The methionine salvage pathway-involving ADI1 inhibits hepatoma growth by epigenetically altering genes expression via elevating S-adenosylmethionine.
Chu YD, Lai HY, Pai LM, Huang YH, Lin YH, Liang KH, Yeh CT
Cell death & disease 2019 Mar 11;10(3):240
Cell death & disease 2019 Mar 11;10(3):240
S-1-Propenylcysteine augments BACH1 degradation and heme oxygenase 1 expression in a nitric oxide-dependent manner in endothelial cells.
Tsuneyoshi T, Kunimura K, Morihara N
Nitric oxide : biology and chemistry 2019 Mar 1;84:22-29
Nitric oxide : biology and chemistry 2019 Mar 1;84:22-29
The role of autophagy in the overexpression of MUC5AC in patients with chronic rhinosinusitis.
Ye Y, Zhao J, Ye J, Jiang X, Liu H, Xie Y, Zhang J, Luo Q
International immunopharmacology 2019 Jun;71:169-180
International immunopharmacology 2019 Jun;71:169-180
Clock mutant promotes osteoarthritis by inhibiting the acetylation of NFκB.
Yuan G, Xu L, Cai T, Hua B, Sun N, Yan Z, Lu C, Qian R
Osteoarthritis and cartilage 2019 Jun;27(6):922-931
Osteoarthritis and cartilage 2019 Jun;27(6):922-931
Cell survival controlled by lens-derived Sema3A-Nrp1 is vital on caffeine-suppressed corneal innervation during chick organogenesis.
Wang G, Jiang LM, Tan BY, Li PZ, Zhang PL, Zhang Y, Cheng X, Ma ZL, Li ZJ, Brand-Saberi B, Yang X
Journal of cellular physiology 2019 Jun;234(6):9826-9838
Journal of cellular physiology 2019 Jun;234(6):9826-9838
Ghrelin regulates sepsis‑induced rat acute gastric injury.
Li B, Lin Q, Guo H, Liu L, Li Y
Molecular medicine reports 2019 Jun;19(6):5424-5432
Molecular medicine reports 2019 Jun;19(6):5424-5432
Bronchial epithelial cell extracellular vesicles ameliorate epithelial-mesenchymal transition in COPD pathogenesis by alleviating M2 macrophage polarization.
He S, Chen D, Hu M, Zhang L, Liu C, Traini D, Grau GE, Zeng Z, Lu J, Zhou G, Xie L, Sun S
Nanomedicine : nanotechnology, biology, and medicine 2019 Jun;18:259-271
Nanomedicine : nanotechnology, biology, and medicine 2019 Jun;18:259-271
YWHA/14-3-3 proteins recognize phosphorylated TFEB by a noncanonical mode for controlling TFEB cytoplasmic localization.
Xu Y, Ren J, He X, Chen H, Wei T, Feng W
Autophagy 2019 Jun;15(6):1017-1030
Autophagy 2019 Jun;15(6):1017-1030
GDF-15 promotes mitochondrial function and proliferation in neuronal HT22 cells.
Liu H, Liu J, Si L, Guo C, Liu W, Liu Y
Journal of cellular biochemistry 2019 Jun;120(6):10530-10547
Journal of cellular biochemistry 2019 Jun;120(6):10530-10547
circ-CSPP1 promotes proliferation, invasion and migration of ovarian cancer cells by acting as a miR-1236-3p sponge.
Li QH, Liu Y, Chen S, Zong ZH, Du YP, Sheng XJ, Zhao Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jun;114:108832
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jun;114:108832
Site-Specific Immobilization of β2-AR Using O6-Benzylguanine Derivative-Functionalized Supporter for High-Throughput Receptor-Targeting Lead Discovery.
Wang J, Wang Y, Liu J, Li Q, Yin G, Zhang Y, Xiao C, Fan T, Zhao X, Zheng X
Analytical chemistry 2019 Jun 4;91(11):7385-7393
Analytical chemistry 2019 Jun 4;91(11):7385-7393
Pseudogene RACGAP1P activates RACGAP1/Rho/ERK signalling axis as a competing endogenous RNA to promote hepatocellular carcinoma early recurrence.
Wang MY, Chen DP, Qi B, Li MY, Zhu YY, Yin WJ, He L, Yu Y, Li ZY, Lin L, Yang F, Lin ZR, Liu JQ
Cell death & disease 2019 Jun 3;10(6):426
Cell death & disease 2019 Jun 3;10(6):426
iTRAQ-based proteomics analysis reveals the deregulated proteins related to liver toxicity induced by melamine with or without cyanuric acid in mice.
Yin RH, Huang C, Yuan J, Li W, Yin RL, Li HS, Dong Q, Li XT, Bai WL
Ecotoxicology and environmental safety 2019 Jun 15;174:618-629
Ecotoxicology and environmental safety 2019 Jun 15;174:618-629
Transection of the cervical sympathetic trunk inhibits the progression of pulmonary arterial hypertension via ERK-1/2 Signalling.
Zhao Y, Xiang R, Peng X, Dong Q, Li D, Yu G, Xiao L, Qin S, Huang W
Respiratory research 2019 Jun 14;20(1):121
Respiratory research 2019 Jun 14;20(1):121
The long non-coding RNA H19 induces hypoxia/reoxygenation injury by up-regulating autophagy in the hepatoma carcinoma cells.
Cui C, Li Z, Wu D
Biological research 2019 Jun 13;52(1):32
Biological research 2019 Jun 13;52(1):32
Role of PM2.5 in the development and progression of COPD and its mechanisms.
Zhao J, Li M, Wang Z, Chen J, Zhao J, Xu Y, Wei X, Wang J, Xie J
Respiratory research 2019 Jun 13;20(1):120
Respiratory research 2019 Jun 13;20(1):120
Epidural adipose tissue-derived mesenchymal stem cell activation induced by lung cancer cells promotes malignancy and EMT of lung cancer.
Wang Y, Chu Y, Ren X, Xiang H, Xi Y, Ma X, Zhu K, Guo Z, Zhou C, Zhang G, Chen B
Stem cell research & therapy 2019 Jun 13;10(1):168
Stem cell research & therapy 2019 Jun 13;10(1):168
The up-regulation of two identified wound healing specific proteins-HSP70 and lysozyme in regenerated Eisenia fetida through transcriptome analysis.
Yang Y, Sun Y, Zhang N, Li J, Zhang C, Duan X, Ding Y, Zhao R, Zheng Z, Geng D, Sun Y
Journal of ethnopharmacology 2019 Jun 12;237:64-73
Journal of ethnopharmacology 2019 Jun 12;237:64-73
Reduction of SIRT1 blunts the protective effects of ischemic post-conditioning in diabetic mice by impairing the Akt signaling pathway.
Ding M, Hu L, Yang H, Gao C, Zeng K, Yu M, Feng J, Qiu J, Liu C, Fu F, Li Y
Biochimica et biophysica acta. Molecular basis of disease 2019 Jun 1;1865(6):1677-1689
Biochimica et biophysica acta. Molecular basis of disease 2019 Jun 1;1865(6):1677-1689
MiR-664-2 impacts pubertal development in a precocious-puberty rat model through targeting the NMDA receptor-1†.
Ju M, Yang L, Zhu J, Chen Z, Zhang M, Yu J, Tian Z
Biology of reproduction 2019 Jun 1;100(6):1536-1548
Biology of reproduction 2019 Jun 1;100(6):1536-1548
Protective effects of pyrroloquinoline quinine against oxidative stress-induced cellular senescence and inflammation in human renal tubular epithelial cells via Keap1/Nrf2 signaling pathway.
Wang Z, Han N, Zhao K, Li Y, Chi Y, Wang B
International immunopharmacology 2019 Jul;72:445-453
International immunopharmacology 2019 Jul;72:445-453
Exogenous hydrogen sulfide mitigates LPS + ATP-induced inflammation by inhibiting NLRP3 inflammasome activation and promoting autophagy in L02 cells.
Wu D, Zhong P, Wang J, Wang H
Molecular and cellular biochemistry 2019 Jul;457(1-2):145-156
Molecular and cellular biochemistry 2019 Jul;457(1-2):145-156
Echinacoside Alleviates Hypoxic-Ischemic Brain Injury in Neonatal Rat by Enhancing Antioxidant Capacity and Inhibiting Apoptosis.
Wei W, Lan XB, Liu N, Yang JM, Du J, Ma L, Zhang WJ, Niu JG, Sun T, Yu JQ
Neurochemical research 2019 Jul;44(7):1582-1592
Neurochemical research 2019 Jul;44(7):1582-1592
Normoxia is not favorable for maintaining stemness of human endothelial progenitor cells.
Lin Y, Liu B, Deng T, Zhong J, Feng Z, Zeng Q, Huang G, Chen Z
Stem cell research 2019 Jul;38:101464
Stem cell research 2019 Jul;38:101464
GSTO1 acts as a mediator in sodium fluoride-induced alterations of learning and memory related factors expressions in the hippocampus cell line.
Wang J, Gao Y, Cheng X, Yang J, Zhao Y, Xu H, Zhu Y, Yan Z, Manthari RK, Ommati MM, Wang J
Chemosphere 2019 Jul;226:201-209
Chemosphere 2019 Jul;226:201-209
c‑Jun N‑terminal kinase/transforming growth factor‑β/Smad3 pathway: Is it associated with endoplasmic reticulum stress‑mediated renal interstitial fibrosis?
Liu Y, Shen P, Zhou Y, Tang L, Chai H
Molecular medicine reports 2019 Jul;20(1):755-762
Molecular medicine reports 2019 Jul;20(1):755-762
Toxicity mechanism of sevoflurane in neural stem cells of rats through DNA methylation.
Wang K, Tian Y, Zhang Y, Li X, Wei X, Hu H, Xu S
Experimental and therapeutic medicine 2019 Jul;18(1):237-241
Experimental and therapeutic medicine 2019 Jul;18(1):237-241
Aloperine suppresses human pulmonary vascular smooth muscle cell proliferation via inhibiting inflammatory response.
Chang Z, Zhang P, Zhang M, Jun F, Hu Z, Yang J, Wu Y, Zhou R
The Chinese journal of physiology 2019 Jul-Aug;62(4):157-165
The Chinese journal of physiology 2019 Jul-Aug;62(4):157-165
Deciphering novel biomarkers of lymph node metastasis of thyroid papillary microcarcinoma using proteomic analysis of ultrasound-guided fine-needle aspiration biopsy samples.
Lin P, Yao Z, Sun Y, Li W, Liu Y, Liang K, Liu Y, Qin J, Hou X, Chen L
Journal of proteomics 2019 Jul 30;204:103414
Journal of proteomics 2019 Jul 30;204:103414
Precise and systematic survey of the efficacy of multicomponent drugs against functional dyspepsia.
Wei J, Man Q, Guo F, Xian M, Wang T, Tang C, Zhang Y, Li D, Tang D, Yang H, Huang L
Scientific reports 2019 Jul 24;9(1):10713
Scientific reports 2019 Jul 24;9(1):10713
Insulin secretion impairment induced by rosuvastatin partly though autophagy in INS-1E cells.
Qian L, Zhu K, Lin Y, An L, Huang F, Yao Y, Ren L
Cell biology international 2019 Jul 24;
Cell biology international 2019 Jul 24;
Nek2 augments sorafenib resistance by regulating the ubiquitination and localization of β-catenin in hepatocellular carcinoma.
Deng L, Sun J, Chen X, Liu L, Wu D
Journal of experimental & clinical cancer research : CR 2019 Jul 18;38(1):316
Journal of experimental & clinical cancer research : CR 2019 Jul 18;38(1):316
miR-629-5p promotes growth and metastasis of hepatocellular carcinoma by activating β-catenin.
Tao X, Yang X, Wu K, Yang L, Huang Y, Jin Q, Chen S
Experimental cell research 2019 Jul 15;380(2):124-130
Experimental cell research 2019 Jul 15;380(2):124-130
Mitophagy is a protective response against oxidative damage in bone marrow mesenchymal stem cells.
Fan P, Yu XY, Xie XH, Chen CH, Zhang P, Yang C, Peng X, Wang YT
Life sciences 2019 Jul 15;229:36-45
Life sciences 2019 Jul 15;229:36-45
Multi-walled carbon nanotubes promoted lipid accumulation in human aortic smooth muscle cells.
Yang H, Li J, Yang C, Liu H, Cao Y
Toxicology and applied pharmacology 2019 Jul 1;374:11-19
Toxicology and applied pharmacology 2019 Jul 1;374:11-19
Hypericum perforatum L. supplementation protects sciatic nerve injury-induced apoptotic, inflammatory and oxidative damage to muscle, blood and brain in rats.
Uslusoy F, Nazıroğlu M, Övey İS, Sönmez TT
The Journal of pharmacy and pharmacology 2019 Jan;71(1):83-92
The Journal of pharmacy and pharmacology 2019 Jan;71(1):83-92
S1P promotes inflammation-induced tube formation by HLECs via the S1PR1/NF-κB pathway.
Zheng Z, Zeng YZ, Ren K, Zhu X, Tan Y, Li Y, Li Q, Yi GH
International immunopharmacology 2019 Jan;66:224-235
International immunopharmacology 2019 Jan;66:224-235
Overexpression of CDCA8 promotes the malignant progression of cutaneous melanoma and leads to poor prognosis.
Ci C, Tang B, Lyu D, Liu W, Qiang D, Ji X, Qiu X, Chen L, Ding W
International journal of molecular medicine 2019 Jan;43(1):404-412
International journal of molecular medicine 2019 Jan;43(1):404-412
Regulation of host cell pyroptosis and cytokines production by Mycobacterium tuberculosis effector PPE60 requires LUBAC mediated NF-κB signaling.
Gong Z, Kuang Z, Li H, Li C, Ali MK, Huang F, Li P, Li Q, Huang X, Ren S, Li J, Xie J
Cellular immunology 2019 Jan;335:41-50
Cellular immunology 2019 Jan;335:41-50
Induction of Endoplasmic Reticulum Stress by Cadmium and Its Regulation on Nrf2 Signaling Pathway in Kidneys of Rats.
Chen ZJ, Chen JX, Wu LK, Li BY, Tian YF, Xian M, Huang ZP, Yu RA
Biomedical and environmental sciences : BES 2019 Jan;32(1):1-10
Biomedical and environmental sciences : BES 2019 Jan;32(1):1-10
Radioprotective effects of roxadustat (FG-4592) in haematopoietic system.
Zhang P, Du J, Zhao H, Cheng Y, Dong S, Yang Y, Li B, Gao F, Sun X, Cai J, Liu C
Journal of cellular and molecular medicine 2019 Jan;23(1):349-356
Journal of cellular and molecular medicine 2019 Jan;23(1):349-356
BPTF promotes hepatocellular carcinoma growth by modulating hTERT signaling and cancer stem cell traits.
Zhao X, Zheng F, Li Y, Hao J, Tang Z, Tian C, Yang Q, Zhu T, Diao C, Zhang C, Chen M, Hu S, Guo P, Zhang L, Liao Y, Yu W, Chen M, Zou L, Guo W, Deng W
Redox biology 2019 Jan;20:427-441
Redox biology 2019 Jan;20:427-441
PARP inhibitor re‑sensitizes Adriamycin resistant leukemia cells through DNA damage and apoptosis.
Wu J, Xiao S, Yuan M, Li Q, Xiao G, Wu W, Ouyang Y, Huang L, Yao C
Molecular medicine reports 2019 Jan;19(1):75-84
Molecular medicine reports 2019 Jan;19(1):75-84
Constitutive androstane receptor weakens the induction of panaxytriol on CYP3A4 by repressing the activation of pregnane X receptor.
Hu Q, Yao N, Wu J, Liu M, Liu F, Zhang H, Xiong Y, Xia C
Biochemical pharmacology 2019 Jan;159:32-39
Biochemical pharmacology 2019 Jan;159:32-39
DEP domain containing 1 predicts prognosis of hepatocellular carcinoma patients and regulates tumor proliferation and metastasis.
Qu D, Cui F, Lu D, Yang Y, Xu Y
Cancer science 2019 Jan;110(1):157-165
Cancer science 2019 Jan;110(1):157-165
Zerumbone inhibits migration in ESCC via promoting Rac1 ubiquitination.
Wang M, Niu J, Gao L, Gao Y, Gao S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jan;109:2447-2455
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jan;109:2447-2455
FS-7 inhibits MGC-803 cells growth in vitro and in vivo via down-regulating glycolysis.
Deng X, Li Z, Xiong R, Liu J, Liu R, Peng J, Chen Y, Lei X, Cao X, Zheng X, Xie Z, Tang G
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jan;109:1659-1669
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jan;109:1659-1669
Nerve injury elevates functional Cav3.2 channels in superficial spinal dorsal horn.
Feng XJ, Ma LX, Jiao C, Kuang HX, Zeng F, Zhou XY, Cheng XE, Zhu MY, Zhang DY, Jiang CY, Liu T
Molecular pain 2019 Jan-Dec;15:1744806919836569
Molecular pain 2019 Jan-Dec;15:1744806919836569
Dexamethasone interferes with osteoblasts formation during osteogenesis through altering IGF-1-mediated angiogenesis.
Xu S, Guo R, Li PZ, Li K, Yan Y, Chen J, Wang G, Brand-Saberi B, Yang X, Cheng X
Journal of cellular physiology 2019 Jan 22;
Journal of cellular physiology 2019 Jan 22;
Differential response to lead toxicity in rat primary microglia and astrocytes.
Peng J, Zhou F, Wang Y, Xu Y, Zhang H, Zou F, Meng X
Toxicology and applied pharmacology 2019 Jan 15;363:64-71
Toxicology and applied pharmacology 2019 Jan 15;363:64-71
Melatonin protects against sepsis-induced cardiac dysfunction by regulating apoptosis and autophagy via activation of SIRT1 in mice.
Zhang WX, He BM, Wu Y, Qiao JF, Peng ZY
Life sciences 2019 Jan 15;217:8-15
Life sciences 2019 Jan 15;217:8-15
miR-429 and miR-424-5p inhibit cell proliferation and Ca2+ influx by downregulating CaSR in pulmonary artery smooth muscle cells.
Li C, Qin F, Xue M, Lei Y, Hu F, Xu H, Sun G, Wang T, Guo M
American journal of physiology. Cell physiology 2019 Jan 1;316(1):C111-C120
American journal of physiology. Cell physiology 2019 Jan 1;316(1):C111-C120
Sulforaphane Improves Lipid Metabolism by Enhancing Mitochondrial Function and Biogenesis In Vivo and In Vitro.
Lei P, Tian S, Teng C, Huang L, Liu X, Wang J, Zhang Y, Li B, Shan Y
Molecular nutrition & food research 2019 Feb;63(4):e1800795
Molecular nutrition & food research 2019 Feb;63(4):e1800795
Citrate reduced oxidative damage in stem cells by regulating cellular redox signaling pathways and represent a potential treatment for oxidative stress-induced diseases.
Wu X, Dai H, Liu L, Xu C, Yin Y, Yi J, Bielec MD, Han Y, Li S
Redox biology 2019 Feb;21:101057
Redox biology 2019 Feb;21:101057
Strand break-induced replication fork collapse leads to C-circles, C-overhangs and telomeric recombination.
Zhang T, Zhang Z, Shengzhao G, Li X, Liu H, Zhao Y
PLoS genetics 2019 Feb;15(2):e1007925
PLoS genetics 2019 Feb;15(2):e1007925
Exogenous Tetranectin Protects Against 1-Methyl-4-Phenylpyridine-Induced Neurotoxicity by Inhibiting Apoptosis and Autophagy Through Ribosomal Protein S6 Kinase Beta-1.
Xie Q, Liu M, Yan YF, Shen X, Wang ES
World neurosurgery 2019 Feb;122:e375-e382
World neurosurgery 2019 Feb;122:e375-e382
Interferon-alpha promotes immunosuppression through IFNAR1/STAT1 signalling in head and neck squamous cell carcinoma.
Ma H, Yang W, Zhang L, Liu S, Zhao M, Zhou G, Wang L, Jin S, Zhang Z, Hu J
British journal of cancer 2019 Feb;120(3):317-330
British journal of cancer 2019 Feb;120(3):317-330
A coronary artery disease-associated tRNAThr mutation altered mitochondrial function, apoptosis and angiogenesis.
Jia Z, Zhang Y, Li Q, Ye Z, Liu Y, Fu C, Cang X, Wang M, Guan MX
Nucleic acids research 2019 Feb 28;47(4):2056-2074
Nucleic acids research 2019 Feb 28;47(4):2056-2074
Protective effect of oxytocin on LPS-induced acute lung injury in mice.
An X, Sun X, Hou Y, Yang X, Chen H, Zhang P, Wu J
Scientific reports 2019 Feb 26;9(1):2836
Scientific reports 2019 Feb 26;9(1):2836
Long noncoding RNA HOTAIR regulates autophagy via the miR-20b-5p/ATG7 axis in hepatic ischemia/reperfusion injury.
Tang B, Bao N, He G, Wang J
Gene 2019 Feb 20;686:56-62
Gene 2019 Feb 20;686:56-62
Carnosol as a Nrf2 Activator Improves Endothelial Barrier Function Through Antioxidative Mechanisms.
Li X, Zhang Q, Hou N, Li J, Liu M, Peng S, Zhang Y, Luo Y, Zhao B, Wang S, Zhang Y, Qiao Y
International journal of molecular sciences 2019 Feb 18;20(4)
International journal of molecular sciences 2019 Feb 18;20(4)
MiR-223-3p functions as a tumor suppressor in lung squamous cell carcinoma by miR-223-3p-mutant p53 regulatory feedback loop.
Luo P, Wang Q, Ye Y, Zhang J, Lu D, Cheng L, Zhou H, Xie M, Wang B
Journal of experimental & clinical cancer research : CR 2019 Feb 12;38(1):74
Journal of experimental & clinical cancer research : CR 2019 Feb 12;38(1):74
Autophagy inhibition potentiates the anti-angiogenic property of multikinase inhibitor anlotinib through JAK2/STAT3/VEGFA signaling in non-small cell lung cancer cells.
Liang L, Hui K, Hu C, Wen Y, Yang S, Zhu P, Wang L, Xia Y, Qiao Y, Sun W, Fei J, Chen T, Zhao F, Yang B, Jiang X
Journal of experimental & clinical cancer research : CR 2019 Feb 12;38(1):71
Journal of experimental & clinical cancer research : CR 2019 Feb 12;38(1):71
Protective Effect of Koumine, an Alkaloid from Gelsemium Sempervirens, on Injury Induced by H₂O₂ in IPEC-J2 Cells.
Yuan Z, Liang Z, Yi J, Chen X, Li R, Wu Y, Wu J, Sun Z
International journal of molecular sciences 2019 Feb 11;20(3)
International journal of molecular sciences 2019 Feb 11;20(3)
Blockade of glycolysis-dependent contraction by oroxylin a via inhibition of lactate dehydrogenase-a in hepatic stellate cells.
Wang F, Jia Y, Li M, Wang L, Shao J, Guo Q, Tan S, Ding H, Chen A, Zhang F, Zheng S
Cell communication and signaling : CCS 2019 Feb 11;17(1):11
Cell communication and signaling : CCS 2019 Feb 11;17(1):11
Identification of diterpenoid compounds that interfere with Fli-1 DNA binding to suppress leukemogenesis.
Liu T, Xia L, Yao Y, Yan C, Fan Y, Gajendran B, Yang J, Li YJ, Chen J, Filmus J, Spaner DE, Zacksenhaus E, Hao X, Ben-David Y
Cell death & disease 2019 Feb 11;10(2):117
Cell death & disease 2019 Feb 11;10(2):117
Nano-Gold Loaded with Resveratrol Enhance the Anti-Hepatoma Effect of Resveratrol In Vitro and In Vivo.
Zhang D, Zhang J, Zeng J, Li Z, Zuo H, Huang C, Zhao X
Journal of biomedical nanotechnology 2019 Feb 1;15(2):288-300
Journal of biomedical nanotechnology 2019 Feb 1;15(2):288-300
Propofol Attenuates Hypoxia/Reoxygenation-Induced Apoptosis and Autophagy in HK-2 Cells by Inhibiting JNK Activation.
Wang H, Peng X, Huang Y, Xiao Y, Wang Z, Zhan L
Yonsei medical journal 2019 Dec;60(12):1195-1202
Yonsei medical journal 2019 Dec;60(12):1195-1202
Effect of hydrogen-rich water on the Nrf2/ARE signaling pathway in rats with myocardial ischemia-reperfusion injury.
Li L, Liu T, Liu L, Li S, Zhang Z, Zhang R, Zhou Y, Liu F
Journal of bioenergetics and biomembranes 2019 Dec;51(6):393-402
Journal of bioenergetics and biomembranes 2019 Dec;51(6):393-402
Molecular mechanism of miR-204 regulates proliferation, apoptosis and autophagy of cervical cancer cells by targeting ATF2.
Li N, Guo X, Liu L, Wang L, Cheng R
Artificial cells, nanomedicine, and biotechnology 2019 Dec;47(1):2529-2535
Artificial cells, nanomedicine, and biotechnology 2019 Dec;47(1):2529-2535
Osteoadherin serves roles in the regulation of apoptosis and growth in MC3T3‑E1 osteoblast cells.
Hamaya E, Fujisawa T, Tamura M
International journal of molecular medicine 2019 Dec;44(6):2336-2344
International journal of molecular medicine 2019 Dec;44(6):2336-2344
Bexarotene Attenuates Focal Cerebral Ischemia-Reperfusion Injury via the Suppression of JNK/Caspase-3 Signaling Pathway.
Liu H, Liu S, Tian X, Wang Q, Rao J, Wang Y, Xiang F, Zheng H, Xu L, Dong Z
Neurochemical research 2019 Dec;44(12):2809-2820
Neurochemical research 2019 Dec;44(12):2809-2820
Design, synthesis and molecular mechanisms of novel dual inhibitors of heat shock protein 90/phosphoinositide 3-kinase alpha (Hsp90/PI3Kα) against cutaneous melanoma.
Qin F, Wang Y, Jiang X, Wang Y, Zhang N, Wen X, Wang L, Jiang Q, He G
Journal of enzyme inhibition and medicinal chemistry 2019 Dec;34(1):909-926
Journal of enzyme inhibition and medicinal chemistry 2019 Dec;34(1):909-926
Silencing ubiquitin-conjugating enzyme 2C inhibits proliferation and epithelial-mesenchymal transition in pancreatic ductal adenocarcinoma.
Wang X, Yin L, Yang L, Zheng Y, Liu S, Yang J, Cui H, Wang H
The FEBS journal 2019 Dec;286(24):4889-4909
The FEBS journal 2019 Dec;286(24):4889-4909
Hepatoprotective effects of zinc (II) via cytochrome P-450/reactive oxygen species and canonical apoptosis pathways after arsenite waterborne exposure in common carp.
Zhao H, Wang Y, Guo M, Fei D, Mu M, Yu H, Xing M
Chemosphere 2019 Dec;236:124869
Chemosphere 2019 Dec;236:124869
CircRhoC promotes tumorigenicity and progression in ovarian cancer by functioning as a miR-302e sponge to positively regulate VEGFA.
Wang LL, Zong ZH, Liu Y, Guan X, Chen S, Zhao Y
Journal of cellular and molecular medicine 2019 Dec;23(12):8472-8481
Journal of cellular and molecular medicine 2019 Dec;23(12):8472-8481
Protective effects of betaine on diabetic induced disruption of the male mice blood-testis barrier by regulating oxidative stress-mediated p38 MAPK pathways.
Jiang YP, Yang JM, Ye RJ, Liu N, Zhang WJ, Ma L, Zheng P, Niu JG, Liu P, Yu JQ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109474
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109474
Glycogen phosphorylase B promotes ovarian cancer progression via Wnt/β-catenin signaling and is regulated by miR-133a-3p.
Zhou Y, Jin Z, Wang C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109449
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109449
Differential immune responses of C57BL/6 mice to infection by Salmonella enterica serovar Typhimurium strain SL1344, CVCC541 and CMCC50115.
Wei S, Huang J, Liu Z, Wang M, Zhang B, Lian Z, Guo Y, Han H
Virulence 2019 Dec;10(1):248-259
Virulence 2019 Dec;10(1):248-259
circPUM1 Promotes Tumorigenesis and Progression of Ovarian Cancer by Sponging miR-615-5p and miR-6753-5p.
Guan X, Zong ZH, Liu Y, Chen S, Wang LL, Zhao Y
Molecular therapy. Nucleic acids 2019 Dec 6;18:882-892
Molecular therapy. Nucleic acids 2019 Dec 6;18:882-892
Dietary Curcumin Supplementation Increases Antioxidant Capacity, Upregulates Nrf2 and Hmox1 Levels in the Liver of Piglet Model with Intrauterine Growth Retardation.
Niu Y, He J, Ahmad H, Shen M, Zhao Y, Gan Z, Zhang L, Zhong X, Wang C, Wang T
Nutrients 2019 Dec 5;11(12)
Nutrients 2019 Dec 5;11(12)
ATXN3 promotes breast cancer metastasis by deubiquitinating KLF4.
Zou H, Chen H, Zhou Z, Wan Y, Liu Z
Cancer letters 2019 Dec 28;467:19-28
Cancer letters 2019 Dec 28;467:19-28
Autophagy Attenuation Hampers Progesterone Synthesis during the Development of Pregnant Corpus Luteum.
Tang Z, Zhang Z, Zhang H, Wang Y, Zhang Y, Zhao J, Yang H, Wang Z
Cells 2019 Dec 27;9(1)
Cells 2019 Dec 27;9(1)
Dietary Dihydroartemisinin Supplementation Attenuates Hepatic Oxidative Damage of Weaned Piglets with Intrauterine Growth Retardation through the Nrf2/ARE Signaling Pathway.
Zhao Y, Niu Y, He J, Zhang L, Wang C, Wang T
Animals : an open access journal from MDPI 2019 Dec 13;9(12)
Animals : an open access journal from MDPI 2019 Dec 13;9(12)
LPS Inhibits Fatty Acid Absorption in Enterocytes through TNF-α Secreted by Macrophages.
Liu H, Kai L, Du H, Wang X, Wang Y
Cells 2019 Dec 12;8(12)
Cells 2019 Dec 12;8(12)
Icariin targets Nrf2 signaling to inhibit microglia-mediated neuroinflammation.
Zheng Y, Zhu G, He J, Wang G, Li D, Zhang F
International immunopharmacology 2019 Aug;73:304-311
International immunopharmacology 2019 Aug;73:304-311
Disubstituted Dithiolethione ACDT Exerts Neuroprotective Effects Against 6-Hydroxydopamine-Induced Oxidative Stress in SH-SY5Y Cells.
Betharia S, Rondόn-Ortiz AN, Brown DA
Neurochemical research 2019 Aug;44(8):1878-1892
Neurochemical research 2019 Aug;44(8):1878-1892
Abnormal serum vitamin A levels and retinoic acid receptor α expression patterns in children with anorectal malformation.
Wang Z, Wang Q, Gu C, Zhang J, Wang Y
Pediatric surgery international 2019 Aug;35(8):903-910
Pediatric surgery international 2019 Aug;35(8):903-910
Hypoxic postconditioning activates the Wnt/β-catenin pathway and protects against transient global cerebral ischemia through Dkk1 Inhibition and GSK-3β inactivation.
Zhan L, Liu D, Wen H, Hu J, Pang T, Sun W, Xu E
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Aug;33(8):9291-9307
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Aug;33(8):9291-9307
Exosomes from high glucose-treated macrophages activate glomerular mesangial cells via TGF-β1/Smad3 pathway in vivo and in vitro.
Zhu QJ, Zhu M, Xu XX, Meng XM, Wu YG
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Aug;33(8):9279-9290
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Aug;33(8):9279-9290
Bone marrow mesenchymal stem cells could reduce the toxic effects of hexavalent chromium on the liver by decreasing endoplasmic reticulum stress-mediated apoptosis via SIRT1/HIF-1α signaling pathway in rats.
Zhao Y, Yan J, Li AP, Zhang ZL, Li ZR, Guo KJ, Zhao KC, Ruan Q, Guo L
Toxicology letters 2019 Aug;310:31-38
Toxicology letters 2019 Aug;310:31-38
Knockdown of LncRNA SCAMP1 suppressed malignant biological behaviours of glioma cells via modulating miR-499a-5p/LMX1A/NLRC5 pathway.
Zong Z, Song Y, Xue Y, Ruan X, Liu X, Yang C, Zheng J, Cao S, Li Z, Liu Y
Journal of cellular and molecular medicine 2019 Aug;23(8):5048-5062
Journal of cellular and molecular medicine 2019 Aug;23(8):5048-5062
RING finger protein 10 is a potential drug target for diabetic vascular complications.
Li S, Yu G, Huang W, Wang R, Pu P, Chen M
Molecular medicine reports 2019 Aug;20(2):931-938
Molecular medicine reports 2019 Aug;20(2):931-938
Bilirubin alleviates alum-induced peritonitis through inactivation of NLRP3 inflammasome.
Lin Y, Wang S, Yang Z, Gao L, Zhou Z, Yu P, Wu B
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Aug;116:108973
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Aug;116:108973
The expression of cerebrospinal fluid exosomal miR-630 plays an important role in the dysfunction of endothelial cells after subarachnoid hemorrhage.
Sun L, Zhang W, Li Z, Li M, Guo J, Wang H, Wang X
Scientific reports 2019 Aug 8;9(1):11510
Scientific reports 2019 Aug 8;9(1):11510
Cordycepin alleviates hepatic lipid accumulation by inducing protective autophagy via PKA/mTOR pathway.
Li T, Wen L, Cheng B
Biochemical and biophysical research communications 2019 Aug 27;516(3):632-638
Biochemical and biophysical research communications 2019 Aug 27;516(3):632-638
Brilliant Blue G Inhibits Inflammasome Activation and Reduces Disruption of Blood-Spinal Cord Barrier Induced by Spinal Cord Injury in Rats.
Zhou X, Yang Y, Wu L, Wang Y, Du C, Li C, Wang Z, Wang Y
Medical science monitor : international medical journal of experimental and clinical research 2019 Aug 24;25:6359-6366
Medical science monitor : international medical journal of experimental and clinical research 2019 Aug 24;25:6359-6366
miR-205-5p regulates epithelial-mesenchymal transition by targeting PTEN via PI3K/AKT signaling pathway in cisplatin-resistant nasopharyngeal carcinoma cells.
Zhang P, Lu X, Shi Z, Li X, Zhang Y, Zhao S, Liu H
Gene 2019 Aug 20;710:103-113
Gene 2019 Aug 20;710:103-113
Rho-kinase inhibitor attenuates airway mucus hypersecretion and inflammation partly by downregulation of IL-13 and the JNK1/2-AP1 signaling pathway.
Zhang W, Li X, Zhang Y
Biochemical and biophysical research communications 2019 Aug 20;516(2):571-577
Biochemical and biophysical research communications 2019 Aug 20;516(2):571-577
Selective ERK1/2 agonists isolated from Melia azedarach with potent anti-leukemic activity.
Wang N, Fan Y, Yuan CM, Song J, Yao Y, Liu W, Gajendran B, Zacksenhaus E, Li Y, Liu J, Hao XJ, Ben-David Y
BMC cancer 2019 Aug 2;19(1):764
BMC cancer 2019 Aug 2;19(1):764
MiR-146b accelerates osteoarthritis progression by targeting alpha-2-macroglobulin.
Liu X, Liu L, Zhang H, Shao Y, Chen Z, Feng X, Fang H, Zhao C, Pan J, Zhang H, Zeng C, Cai D
Aging 2019 Aug 17;11(16):6014-6028
Aging 2019 Aug 17;11(16):6014-6028
Identification of proteomic signatures associated with COPD frequent exacerbators.
Sun P, Ye R, Wang C, Bai S, Zhao L
Life sciences 2019 Aug 1;230:1-9
Life sciences 2019 Aug 1;230:1-9
Changes among TGF-β1+ Breg cells and helper T cell subsets in a murine model of allergic rhinitis with prolonged OVA challenge.
Wang M, Gu Z, Yang J, Zhao H, Cao Z
International immunopharmacology 2019 Apr;69:347-357
International immunopharmacology 2019 Apr;69:347-357
CD36 plays a negative role in the regulation of lipophagy in hepatocytes through an AMPK-dependent pathway.
Li Y, Yang P, Zhao L, Chen Y, Zhang X, Zeng S, Wei L, Varghese Z, Moorhead JF, Chen Y, Ruan XZ
Journal of lipid research 2019 Apr;60(4):844-855
Journal of lipid research 2019 Apr;60(4):844-855
Simvastatin ameliorates total liver ischemia/reperfusion injury via KLF2-mediated mechanism in rats.
Liu Z, Lai CH, Zhang X, Luo J, Huang X, Qi X, Wang W, Zhong Z, Xiaoli F, Li L, Xiong Y, Senninger N, Wang Y, Ye Q, Ye S
Clinics and research in hepatology and gastroenterology 2019 Apr;43(2):171-178
Clinics and research in hepatology and gastroenterology 2019 Apr;43(2):171-178
High-mobility group box 1 protein modulated proliferation and radioresistance in esophageal squamous cell carcinoma.
Di X, He G, Chen H, Zhu C, Qin Q, Yan J, Zhang X, Sun X
Journal of gastroenterology and hepatology 2019 Apr;34(4):728-735
Journal of gastroenterology and hepatology 2019 Apr;34(4):728-735
Nicotinate-curcumin ameliorates cognitive impairment in diabetic rats by rescuing autophagic flux in CA1 hippocampus.
Gu HF, Li N, Tang YL, Yan CQ, Shi Z, Yi SN, Zhou HL, Liao DF, OuYang XP
CNS neuroscience & therapeutics 2019 Apr;25(4):430-441
CNS neuroscience & therapeutics 2019 Apr;25(4):430-441
CCL18 promotes the metastasis of squamous cell carcinoma of the head and neck through MTDH-NF-κB signalling pathway.
Qin Y, Wang J, Zhu G, Li G, Tan H, Chen C, Pi L, She L, Chen X, Wei M, Li Z, Liu Z, Huang D, Liu Y, Zhang X
Journal of cellular and molecular medicine 2019 Apr;23(4):2689-2701
Journal of cellular and molecular medicine 2019 Apr;23(4):2689-2701
SIRT5-mediated SDHA desuccinylation promotes clear cell renal cell carcinoma tumorigenesis.
Ma Y, Qi Y, Wang L, Zheng Z, Zhang Y, Zheng J
Free radical biology & medicine 2019 Apr;134:458-467
Free radical biology & medicine 2019 Apr;134:458-467
Changes in the levels of 12/15-lipoxygenase, apoptosis-related proteins and inflammatory factors in the cortex of diabetic rats and the neuroprotection of baicalein.
Li Y, Chen Q, Ran D, Wang H, Du W, Luo Y, Jiang W, Yang Y, Yang J
Free radical biology & medicine 2019 Apr;134:239-247
Free radical biology & medicine 2019 Apr;134:239-247
The toxicity of multi-walled carbon nanotubes (MWCNTs) to human endothelial cells: The influence of diameters of MWCNTs.
Zhao X, Chang S, Long J, Li J, Li X, Cao Y
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2019 Apr;126:169-177
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2019 Apr;126:169-177
Effects of myostatin deficiency on PGC-1α and FNDC5 expression in three different murine muscle types.
Bai Y, Bi H, Li L, Li J, Yu X, Ren H, Li Y, Ji Y, Li H, Wang H
Acta histochemica 2019 Apr;121(3):323-329
Acta histochemica 2019 Apr;121(3):323-329
Prolonged high-glucose exposure decreased SREBP-1/FASN/ACC in Schwann cells of diabetic mice via blocking PI3K/Akt pathway.
Zhu L, Du W, Liu Y, Cheng M, Wang X, Zhang C, Lv X, Li F, Zhao S, Hao J
Journal of cellular biochemistry 2019 Apr;120(4):5777-5789
Journal of cellular biochemistry 2019 Apr;120(4):5777-5789
MiRNA-29a modulates visceral hyperalgesia in irritable bowel syndrome by targeting HTR7.
Zhu H, Xiao X, Chai Y, Li D, Yan X, Tang H
Biochemical and biophysical research communications 2019 Apr 9;511(3):671-678
Biochemical and biophysical research communications 2019 Apr 9;511(3):671-678
Long non-coding RNA GBCDRlnc1 induces chemoresistance of gallbladder cancer cells by activating autophagy.
Cai Q, Wang S, Jin L, Weng M, Zhou D, Wang J, Tang Z, Quan Z
Molecular cancer 2019 Apr 5;18(1):82
Molecular cancer 2019 Apr 5;18(1):82
The Anticonvulsant Effects of Baldrinal on Pilocarpine-Induced convulsion in Adult Male Mice.
Zhang X, Li X, Liu N, Zheng P, Ma L, Guo F, Sun T, Zhou R, Yu J
Molecules (Basel, Switzerland) 2019 Apr 24;24(8)
Molecules (Basel, Switzerland) 2019 Apr 24;24(8)
Effects of agomelatine in rotenone-induced Parkinson's disease in rats.
Günaydın C, Avcı B, Bozkurt A, Önger ME, Balcı H, Bilge SS
Neuroscience letters 2019 Apr 23;699:71-76
Neuroscience letters 2019 Apr 23;699:71-76
Ginsenoside Rk1 induces cell cycle arrest and apoptosis in MDA-MB-231 triple negative breast cancer cells.
Hong Y, Fan D
Toxicology 2019 Apr 15;418:22-31
Toxicology 2019 Apr 15;418:22-31
The effect of di-2-ethylhexyl phthalate on inflammation and lipid metabolic disorder in rats.
Zhou L, Chen H, Xu Q, Han X, Zhao Y, Song X, Zhao T, Ye L
Ecotoxicology and environmental safety 2019 Apr 15;170:391-398
Ecotoxicology and environmental safety 2019 Apr 15;170:391-398
Transketolase (TKT) activity and nuclear localization promote hepatocellular carcinoma in a metabolic and a non-metabolic manner.
Qin Z, Xiang C, Zhong F, Liu Y, Dong Q, Li K, Shi W, Ding C, Qin L, He F
Journal of experimental & clinical cancer research : CR 2019 Apr 11;38(1):154
Journal of experimental & clinical cancer research : CR 2019 Apr 11;38(1):154
Microglial NLRP3 inflammasome activation mediates IL-1β release and contributes to central sensitization in a recurrent nitroglycerin-induced migraine model.
He W, Long T, Pan Q, Zhang S, Zhang Y, Zhang D, Qin G, Chen L, Zhou J
Journal of neuroinflammation 2019 Apr 10;16(1):78
Journal of neuroinflammation 2019 Apr 10;16(1):78
TCF7L1 indicates prognosis and promotes proliferation through activation of Keap1/NRF2 in gastric cancer.
Zhang B, Wu J, Cai Y, Luo M, Wang B, Gu Y
Acta biochimica et biophysica Sinica 2019 Apr 1;51(4):375-385
Acta biochimica et biophysica Sinica 2019 Apr 1;51(4):375-385
Inhibition of soluble epoxide hydrolase ameliorates hyperhomocysteinemia-induced hepatic steatosis by enhancing β-oxidation of fatty acid in mice.
Yao L, Cao B, Cheng Q, Cai W, Ye C, Liang J, Liu W, Tan L, Yan M, Li B, He J, Hwang SH, Zhang X, Wang C, Ai D, Hammock BD, Zhu Y
American journal of physiology. Gastrointestinal and liver physiology 2019 Apr 1;316(4):G527-G538
American journal of physiology. Gastrointestinal and liver physiology 2019 Apr 1;316(4):G527-G538
High Expression of lncRNA AFAP1-AS1 Promotes the Progression of Colon Cancer and Predicts Poor Prognosis.
Bo H, Fan L, Li J, Liu Z, Zhang S, Shi L, Guo C, Li X, Liao Q, Zhang W, Zhou M, Xiang B, Li X, Li G, Xiong W, Zeng Z, Xiong F, Gong Z
Journal of Cancer 2018;9(24):4677-4683
Journal of Cancer 2018;9(24):4677-4683
Trio-Based Deep Sequencing Reveals a Low Incidence of Off-Target Mutations in the Offspring of Genetically Edited Goats.
Li C, Zhou S, Li Y, Li G, Ding Y, Li L, Liu J, Qu L, Sonstegard T, Huang X, Jiang Y, Chen Y, Petersen B, Wang X
Frontiers in genetics 2018;9:449
Frontiers in genetics 2018;9:449
Fangchinoline Ameliorates the Expressions of Angiogenic Molecule in Cerebral Ischemia Induced Neuronal Degeneration in Neonatal Rats.
Daicheng H, Shiwen X, Huaping Z, Yong L, Qianqian Z, Changxia H
Translational neuroscience 2018;9:117-122
Translational neuroscience 2018;9:117-122
Snx27 Deletion Promotes Recovery From Spinal Cord Injury by Neuroprotection and Reduces Macrophage/Microglia Proliferation.
Zeng Y, Wang N, Guo T, Zheng Q, Wang S, Wu S, Li X, Wu J, Chen Z, Xu H, Wang X, Lin B
Frontiers in neurology 2018;9:1059
Frontiers in neurology 2018;9:1059
Adipocytes fuel gastric cancer omental metastasis via PITPNC1-mediated fatty acid metabolic reprogramming.
Tan Y, Lin K, Zhao Y, Wu Q, Chen D, Wang J, Liang Y, Li J, Hu J, Wang H, Liu Y, Zhang S, He W, Huang Q, Hu X, Yao Z, Liang B, Liao W, Shi M
Theranostics 2018;8(19):5452-5468
Theranostics 2018;8(19):5452-5468
Th17 cell-derived IL-17A promoted tumor progression via STAT3/NF-κB/Notch1 signaling in non-small cell lung cancer.
Wang R, Yang L, Zhang C, Wang R, Zhang Z, He Q, Chen X, Zhang B, Qin Z, Wang L, Zhang Y
Oncoimmunology 2018;7(11):e1461303
Oncoimmunology 2018;7(11):e1461303
Long Noncoding RNA HOTTIP Promotes Mouse Hepatic Stellate Cell Activation via Downregulating miR-148a.
Li Z, Wang J, Zeng Q, Hu C, Zhang J, Wang H, Yan J, Li H, Yu Z
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;51(6):2814-2828
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;51(6):2814-2828
The FOXK1-CCDC43 Axis Promotes the Invasion and Metastasis of Colorectal Cancer Cells.
Wang J, Liu G, Liu M, Xiang L, Xiao Y, Zhu H, Wu X, Peng Y, Zhang W, Jiang P, Li A, Nan Q, Chen Y, Chen C, Cheng T, Liu S, Wang J
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;51(6):2547-2563
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;51(6):2547-2563
Tumor-Secreted Exosomal miR-222 Promotes Tumor Progression via Regulating P27 Expression and Re-Localization in Pancreatic Cancer.
Li Z, Tao Y, Wang X, Jiang P, Li J, Peng M, Zhang X, Chen K, Liu H, Zhen P, Zhu J, Liu X, Liu X
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;51(2):610-629
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;51(2):610-629
High Concentration of Aspirin Induces Apoptosis in Rat Tendon Stem Cells via Inhibition of the Wnt/β-Catenin Pathway.
Wang Y, Tang H, He G, Shi Y, Kang X, Lyu J, Zhou M, Zhu M, Zhang J, Tang K
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;50(6):2046-2059
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;50(6):2046-2059
Mesenchymal Stem Cell-Derived Exosomes Reduce A1 Astrocytes via Downregulation of Phosphorylated NFκB P65 Subunit in Spinal Cord Injury.
Wang L, Pei S, Han L, Guo B, Li Y, Duan R, Yao Y, Xue B, Chen X, Jia Y
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;50(4):1535-1559
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;50(4):1535-1559
LncRNA PCGEM1 Induces Ovarian Carcinoma Tumorigenesis and Progression Through RhoA Pathway.
Chen S, Wang LL, Sun KX, Liu Y, Guan X, Zong ZH, Zhao Y
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(4):1578-1588
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(4):1578-1588
The influence of GAPT extraction on synapse loss of APPswe/PS1dE9 transgenic mice via adjusting Bcl-2/Bax balance.
Shi J, Zhang X, Ni J, Wei M, Li T, Zhou B, Liu X, Zhang L, Wang P, Tian J, Wang Y
Alzheimer's & dementia (New York, N. Y.) 2018;4:724-736
Alzheimer's & dementia (New York, N. Y.) 2018;4:724-736
The Potential Protective Effect of Curcumin on Amyloid-β-42 Induced Cytotoxicity in HT-22 Cells.
Zhang L, Fang Y, Cheng X, Lian Y, Zeng Z, Wu C, Zhu H, Xu H
BioMed research international 2018;2018:8134902
BioMed research international 2018;2018:8134902
Ingredients from Litsea garrettii as Potential Preventive Agents against Oxidative Insult and Inflammatory Response.
Li YR, Li GH, Sun L, Li L, Liu Y, Kong DG, Wang SQ, Ren DM, Wang XN, Lou HX, Shen T
Oxidative medicine and cellular longevity 2018;2018:7616852
Oxidative medicine and cellular longevity 2018;2018:7616852
Serum and Ectopic Endometrium from Women with Endometriosis Modulate Macrophage M1/M2 Polarization via the Smad2/Smad3 Pathway.
Nie MF, Xie Q, Wu YH, He H, Zou LJ, She XL, Wu XQ
Journal of immunology research 2018;2018:6285813
Journal of immunology research 2018;2018:6285813
Dysfunction of Nrf2-ARE Signaling Pathway: Potential Pathogenesis in the Development of Neurocognitive Impairment in Patients with Moderate to Severe Obstructive Sleep Apnea-Hypopnea Syndrome.
Zhou L, Ouyang R, Luo H, Peng Y, Chen P, Ren S, Liu G
Oxidative medicine and cellular longevity 2018;2018:3529709
Oxidative medicine and cellular longevity 2018;2018:3529709
Fucosterol Protects against Concanavalin A-Induced Acute Liver Injury: Focus on P38 MAPK/NF-κB Pathway Activity.
Mo W, Wang C, Li J, Chen K, Xia Y, Li S, Xu L, Lu X, Wang W, Guo C
Gastroenterology research and practice 2018;2018:2824139
Gastroenterology research and practice 2018;2018:2824139
Effects of Chicory on Serum Uric Acid, Renal Function, and GLUT9 Expression in Hyperuricaemic Rats with Renal Injury and In Vitro Verification with Cells.
Jin YN, Lin ZJ, Zhang B, Bai YF
Evidence-based complementary and alternative medicine : eCAM 2018;2018:1764212
Evidence-based complementary and alternative medicine : eCAM 2018;2018:1764212
Necrostatin-1 promotes ectopic periodontal tissue like structure regeneration in LPS-treated PDLSCs.
Yan B, Zhang H, Dai T, Gu Y, Qiu X, Hu C, Liu Y, Wei K, Li D
PloS one 2018;13(11):e0207760
PloS one 2018;13(11):e0207760
Targeting MAPK Pathways by Naringenin Modulates Microglia M1/M2 Polarization in Lipopolysaccharide-Stimulated Cultures.
Zhang B, Wei YZ, Wang GQ, Li DD, Shi JS, Zhang F
Frontiers in cellular neuroscience 2018;12:531
Frontiers in cellular neuroscience 2018;12:531
Arsenic sulfide amplifies JQ1 toxicity via mitochondrial pathway in gastric and colon cancer cells.
Tan Z, Zhang X, Kang T, Zhang L, Chen S
Drug design, development and therapy 2018;12:3913-3927
Drug design, development and therapy 2018;12:3913-3927
Natural antisense transcript of hypoxia-inducible factor 1 regulates hypoxic cell apoptosis in epithelial ovarian cancer.
Qiu JJ, Lin XJ, Zheng TT, Tang XY, Hua KQ
OncoTargets and therapy 2018;11:9101-9110
OncoTargets and therapy 2018;11:9101-9110
Contribution of dysregulated circRNA_100876 to proliferation and metastasis of esophageal squamous cell carcinoma.
Cao S, Chen G, Yan L, Li L, Huang X
OncoTargets and therapy 2018;11:7385-7394
OncoTargets and therapy 2018;11:7385-7394
Combination Treatment of Icariin and L-DOPA Against 6-OHDA-Lesioned Dopamine Neurotoxicity.
Lu DS, Chen C, Zheng YX, Li DD, Wang GQ, Liu J, Shi J, Zhang F
Frontiers in molecular neuroscience 2018;11:155
Frontiers in molecular neuroscience 2018;11:155
Lithium chloride inhibits cell survival, overcomes drug resistance, and triggers apoptosis in multiple myeloma via activation of the Wnt/β-catenin pathway.
Yao R, Sun X, Xie Y, Liu L, Han D, Yao Y, Li H, Li Z, Xu K
American journal of translational research 2018;10(8):2610-2618
American journal of translational research 2018;10(8):2610-2618
Leucine Carboxyl Methyltransferase Downregulation and Protein Phosphatase Methylesterase Upregulation Contribute Toward the Inhibition of Protein Phosphatase 2A by α-Synuclein.
Tian H, Lu Y, Liu J, Liu W, Lu L, Duan C, Gao G, Yang H
Frontiers in aging neuroscience 2018;10:173
Frontiers in aging neuroscience 2018;10:173
Cdk5 Inhibitory Peptide Prevents Loss of Dopaminergic Neurons and Alleviates Behavioral Changes in an MPTP Induced Parkinson's Disease Mouse Model.
He R, Huang W, Huang Y, Xu M, Song P, Huang Y, Xie H, Hu Y
Frontiers in aging neuroscience 2018;10:162
Frontiers in aging neuroscience 2018;10:162
lncRNA DLEU1 contributes to tumorigenesis and development of endometrial carcinoma by targeting mTOR.
Du Y, Wang L, Chen S, Liu Y, Zhao Y
Molecular carcinogenesis 2018 Sep;57(9):1191-1200
Molecular carcinogenesis 2018 Sep;57(9):1191-1200
Curcumin attenuates resistance to irinotecan via induction of apoptosis of cancer stem cells in chemoresistant colon cancer cells.
Su P, Yang Y, Wang G, Chen X, Ju Y
International journal of oncology 2018 Sep;53(3):1343-1353
International journal of oncology 2018 Sep;53(3):1343-1353
MiR-20a-3p regulates TGF-β1/Survivin pathway to affect keratinocytes proliferation and apoptosis by targeting SFMBT1 in vitro.
Li R, Qiao M, Zhao X, Yan J, Wang X, Sun Q
Cellular signalling 2018 Sep;49:95-104
Cellular signalling 2018 Sep;49:95-104
Resveratrol relieves particulate matter (mean diameter < 2.5 μm)-induced oxidative injury of lung cells through attenuation of autophagy deregulation.
Li Y, Qian W, Wang D, Meng Y, Wang X, Chen Y, Li X, Xie C, Zhong C, Fu S
Journal of applied toxicology : JAT 2018 Sep;38(9):1251-1261
Journal of applied toxicology : JAT 2018 Sep;38(9):1251-1261
Artemisitene suppresses tumorigenesis by inducing DNA damage through deregulating c-Myc-topoisomerase pathway.
Chen J, Li W, Cui K, Ji K, Xu S, Xu Y
Oncogene 2018 Sep;37(37):5079-5087
Oncogene 2018 Sep;37(37):5079-5087
Knockdown of long noncoding RNA GHET1 inhibits cell‑cycle progression and invasion of gastric cancer cells.
Xia Y, Yan Z, Wan Y, Wei S, Bi Y, Zhao J, Liu J, Liao DJ, Huang H
Molecular medicine reports 2018 Sep;18(3):3375-3381
Molecular medicine reports 2018 Sep;18(3):3375-3381
TAM Infiltration Differences in "Tumor-First" and " ZHENG-First" Models and the Underlying Inflammatory Molecular Mechanism in Pancreatic Cancer.
Wang FJ, Wang P, Chen LY, Geng YW, Chen H, Meng ZQ, Liu LM, Chen Z
Integrative cancer therapies 2018 Sep;17(3):707-716
Integrative cancer therapies 2018 Sep;17(3):707-716
Overexpression of SMARCA2 or CAMK2D is associated with cisplatin resistance in human epithelial ovarian cancer.
Xu X, Zheng Z, Jia L, Suo S, Liu B, Shao T, Tu Q, Hua Y, Xu H
Oncology letters 2018 Sep;16(3):3796-3804
Oncology letters 2018 Sep;16(3):3796-3804
Effects of SB202190 on expression levels of IL-6 and NF-κB in flap ischemia-reperfusion injury.
Guo K, Ma J, Liang W
Experimental and therapeutic medicine 2018 Sep;16(3):2522-2526
Experimental and therapeutic medicine 2018 Sep;16(3):2522-2526
2',4'-Dihydroxy-6'-methoxy-3',5'-dimethylchalcone, a potent Nrf2/ARE pathway inhibitor, reverses drug resistance by decreasing glutathione synthesis and drug efflux in BEL-7402/5-FU cells.
Wei X, Mo X, An F, Ji X, Lu Y
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2018 Sep;119:252-259
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2018 Sep;119:252-259
Bexarotene protects against neurotoxicity partially through a PPARγ-dependent mechanism in mice following traumatic brain injury.
He J, Liu H, Zhong J, Guo Z, Wu J, Zhang H, Huang Z, Jiang L, Li H, Zhang Z, Liu L, Wu Y, Qi L, Sun X, Cheng C
Neurobiology of disease 2018 Sep;117:114-124
Neurobiology of disease 2018 Sep;117:114-124
miR-383 negatively regulates osteoblastic differentiation of bone marrow mesenchymal stem cells in rats by targeting Satb2.
Tang J, Zhang Z, Jin X, Shi H
Bone 2018 Sep;114:137-143
Bone 2018 Sep;114:137-143
Oxymatrine Inhibits Transforming Growth Factor β1 (TGF-β1)-Induced Cardiac Fibroblast-to-Myofibroblast Transformation (FMT) by Mediating the Notch Signaling Pathway In Vitro.
Zhao L, Xu Y, Tao L, Yang Y, Shen X, Li L, Luo P
Medical science monitor : international medical journal of experimental and clinical research 2018 Sep 9;24:6280-6288
Medical science monitor : international medical journal of experimental and clinical research 2018 Sep 9;24:6280-6288
Lactate enhanced the effect of parathyroid hormone on osteoblast differentiation via GPR81-PKC-Akt signaling.
Wu Y, Wang M, Zhang K, Li Y, Xu M, Tang S, Qu X, Li C
Biochemical and biophysical research communications 2018 Sep 5;503(2):737-743
Biochemical and biophysical research communications 2018 Sep 5;503(2):737-743
H2A.Z.1 crosstalk with H3K56-acetylation controls gliogenesis through the transcription of folate receptor.
Su L, Xia W, Shen T, Liang Q, Wang W, Li H, Jiao J
Nucleic acids research 2018 Sep 28;46(17):8817-8831
Nucleic acids research 2018 Sep 28;46(17):8817-8831
RING finger protein 10 prevents neointimal hyperplasia by promoting apoptosis in vitro and in vivo.
Yu G, Chen J, Li S, Pu P, Huang W, Zhao Y, Peng X, Wang R, Lei H
Life sciences 2018 Sep 1;208:325-332
Life sciences 2018 Sep 1;208:325-332
miR‑92b promotes autophagy and suppresses viability and invasion in breast cancer by targeting EZH2.
Liu F, Sang M, Meng L, Gu L, Liu S, Li J, Geng C
International journal of oncology 2018 Oct;53(4):1505-1515
International journal of oncology 2018 Oct;53(4):1505-1515
Acrolein-induced autophagy-dependent apoptosis via activation of the lysosomal-mitochondrial pathway in EAhy926 cells.
Luo S, Jiang L, Li Q, Sun X, Liu T, Pei F, Zhang T, Liu T, Dong L, Liu X, Jiang L
Toxicology in vitro : an international journal published in association with BIBRA 2018 Oct;52:146-153
Toxicology in vitro : an international journal published in association with BIBRA 2018 Oct;52:146-153
Erythropoietin Treatment Ameliorates Lupus Nephritis of MRL/lpr Mice.
Zhang Z, Liu D, Zhang X, Wang X
Inflammation 2018 Oct;41(5):1888-1899
Inflammation 2018 Oct;41(5):1888-1899
Association between Tim‑3 and Gal‑9 expression and gastric cancer prognosis.
Wang Y, Zhao E, Zhang Z, Zhao G, Cao H
Oncology reports 2018 Oct;40(4):2115-2126
Oncology reports 2018 Oct;40(4):2115-2126
Low-Dose Radiation Enhanced Inhibition of Breast Tumor Xenograft and Reduced Myocardial Injury Induced by Doxorubicin.
Jiang X, Du Y, Meng X, Zhang H, Zhao D, Zhao L, Chen J, Xiao S, Jiang H
Dose-response : a publication of International Hormesis Society 2018 Oct-Dec;16(4):1559325818813061
Dose-response : a publication of International Hormesis Society 2018 Oct-Dec;16(4):1559325818813061
High expression of WNT7A predicts poor prognosis and promote tumor metastasis in pancreatic ductal adenocarcinoma.
Wu DJ, Jiang YS, He RZ, Tao LY, Yang MW, Fu XL, Yang JY, Zhu K
Scientific reports 2018 Oct 25;8(1):15792
Scientific reports 2018 Oct 25;8(1):15792
Construction of a High-Efficiency Drug and Gene Co-Delivery System for Cancer Therapy from a pH-Sensitive Supramolecular Inclusion between Oligoethylenimine- graft-β-cyclodextrin and Hyperbranched Polyglycerol Derivative.
Zhou X, Xu L, Xu J, Wu J, Kirk TB, Ma D, Xue W
ACS applied materials & interfaces 2018 Oct 24;10(42):35812-35829
ACS applied materials & interfaces 2018 Oct 24;10(42):35812-35829
ERα is a negative regulator of PD-L1 gene transcription in breast cancer.
Liu L, Shen Y, Zhu X, Lv R, Li S, Zhang Z, Shi YG, Tan L
Biochemical and biophysical research communications 2018 Oct 20;505(1):157-161
Biochemical and biophysical research communications 2018 Oct 20;505(1):157-161
Temozolomide-Perillyl alcohol conjugate impairs Mitophagy flux by inducing lysosomal dysfunction in non-small cell lung Cancer cells and sensitizes them to irradiation.
Chang M, Song X, Geng X, Wang X, Wang W, Chen TC, Xie L, Song X
Journal of experimental & clinical cancer research : CR 2018 Oct 16;37(1):250
Journal of experimental & clinical cancer research : CR 2018 Oct 16;37(1):250
CNTNAP4 Impacts Epilepsy Through GABAA Receptors Regulation: Evidence From Temporal Lobe Epilepsy Patients and Mouse Models.
Shangguan Y, Xu X, Ganbat B, Li Y, Wang W, Yang Y, Lu X, Du C, Tian X, Wang X
Cerebral cortex (New York, N.Y. : 1991) 2018 Oct 1;28(10):3491-3504
Cerebral cortex (New York, N.Y. : 1991) 2018 Oct 1;28(10):3491-3504
Cold-induced protein RBM3 orchestrates neurogenesis via modulating Yap mRNA stability in cold stress.
Xia W, Su L, Jiao J
The Journal of cell biology 2018 Oct 1;217(10):3464-3479
The Journal of cell biology 2018 Oct 1;217(10):3464-3479
BF211, a derivative of bufalin, enhances the cytocidal effects in multiple myeloma cells by inhibiting the IL-6/JAK2/STAT3 pathway.
Wu XY, Tian F, Su MH, Wu M, Huang Y, Hu LH, Jin L, Zhu XJ
International immunopharmacology 2018 Nov;64:24-32
International immunopharmacology 2018 Nov;64:24-32
FGF9 modulates Schwann cell myelination in developing nerves and induces a pro-inflammatory environment during injury.
Deng B, Lv W, Duan W, Liu Y, Li Z, Song X, Cui C, Qi X, Wang X, Li C
Journal of cellular biochemistry 2018 Nov;119(10):8643-8658
Journal of cellular biochemistry 2018 Nov;119(10):8643-8658
Pyroptosis of HUVECs can be induced by heat stroke.
Pei Y, Geng Y, Su L
Biochemical and biophysical research communications 2018 Nov 30;506(3):626-631
Biochemical and biophysical research communications 2018 Nov 30;506(3):626-631
Luteolin sensitizes the antitumor effect of cisplatin in drug-resistant ovarian cancer via induction of apoptosis and inhibition of cell migration and invasion.
Wang H, Luo Y, Qiao T, Wu Z, Huang Z
Journal of ovarian research 2018 Nov 19;11(1):93
Journal of ovarian research 2018 Nov 19;11(1):93
Lysyl oxidase blockade ameliorates anovulation in polycystic ovary syndrome.
Zhang C, Ma J, Wang W, Sun Y, Sun K
Human reproduction (Oxford, England) 2018 Nov 1;33(11):2096-2106
Human reproduction (Oxford, England) 2018 Nov 1;33(11):2096-2106
Decrease of galectin-3 in keratinocytes: A potential diagnostic marker and a critical contributor to the pathogenesis of psoriasis.
Shi ZR, Tan GZ, Cao CX, Han YF, Meng Z, Man XY, Jiang ZX, Zhang YP, Dang NN, Wei KH, Bu DF, Liu FT, Wang L
Journal of autoimmunity 2018 May;89:30-40
Journal of autoimmunity 2018 May;89:30-40
The inhibitory effect in Fraxinellone on oxidative stress-induced senescence correlates with AMP-activated protein kinase-dependent autophagy restoration.
Han X, Chen H, Zhou J, Tai H, Gong H, Wang X, Huang N, Qin J, Fang T, Wang F, Xiao H
Journal of cellular physiology 2018 May;233(5):3945-3954
Journal of cellular physiology 2018 May;233(5):3945-3954
PD-L1 confers glioblastoma multiforme malignancy via Ras binding and Ras/Erk/EMT activation.
Qiu XY, Hu DX, Chen WQ, Chen RQ, Qian SR, Li CY, Li YJ, Xiong XX, Liu D, Pan F, Yu SB, Chen XQ
Biochimica et biophysica acta. Molecular basis of disease 2018 May;1864(5 Pt A):1754-1769
Biochimica et biophysica acta. Molecular basis of disease 2018 May;1864(5 Pt A):1754-1769
Reversing Multidrug Resistance by Multiplexed Gene Silencing for Enhanced Breast Cancer Chemotherapy.
Li Y, Gao X, Yu Z, Liu B, Pan W, Li N, Tang B
ACS applied materials & interfaces 2018 May 9;10(18):15461-15466
ACS applied materials & interfaces 2018 May 9;10(18):15461-15466
Oxyresveratrol prevents lipopolysaccharide/d-galactosamine-induced acute liver injury in mice.
Jia YN, Lu HP, Peng YL, Zhang BS, Gong XB, Su J, Zhou Y, Pan MH, Xu L
International immunopharmacology 2018 Mar;56:105-112
International immunopharmacology 2018 Mar;56:105-112
Donor Treatment With a Hypoxia-Inducible Factor-1 Agonist Prevents Donation After Cardiac Death Liver Graft Injury in a Rat Isolated Perfusion Model.
Zhang X, Liu Z, Xiao Q, Zeng C, Lai CH, Fan X, Ye Q, Wang Y, Xiong Y
Artificial organs 2018 Mar;42(3):280-289
Artificial organs 2018 Mar;42(3):280-289
Proteomics analysis of altered proteins in kidney of mice with aristolochic acid nephropathy using the fluorogenic derivatization-liquid chromatography-tandem mass spectrometry method.
Lin CE, Chang WS, Lee JA, Chang TY, Huang YS, Hirasaki Y, Chen HS, Imai K, Chen SM
Biomedical chromatography : BMC 2018 Mar;32(3)
Biomedical chromatography : BMC 2018 Mar;32(3)
Expression of diaphragmatic myostatin and correlation with apoptosis in rats with chronic obstructive pulmonary disease.
Zhou X, Yi D, Wu Y, Pei X, Yu H, Chen Y, Jiang Y, Li W
Experimental and therapeutic medicine 2018 Mar;15(3):2295-2300
Experimental and therapeutic medicine 2018 Mar;15(3):2295-2300
Lipoxin A4 improves erectile dysfunction in rats with type I diabetes by inhibiting oxidative stress and corporal fibrosis.
Cui K, Tang Z, Li CC, Wang T, Rao K, Wang SG, Liu JH, Chen Z
Asian journal of andrology 2018 Mar-Apr;20(2):166-172
Asian journal of andrology 2018 Mar-Apr;20(2):166-172
Marine Bacterial Polysaccharide EPS11 Inhibits Cancer Cell Growth via Blocking Cell Adhesion and Stimulating Anoikis.
Cao R, Jin W, Shan Y, Wang J, Liu G, Kuang S, Sun C
Marine drugs 2018 Mar 8;16(3)
Marine drugs 2018 Mar 8;16(3)
AMPK alleviates endoplasmic reticulum stress by inducing the ER-chaperone ORP150 via FOXO1 to protect human bronchial cells from apoptosis.
Liu JQ, Zhang L, Yao J, Yao S, Yuan T
Biochemical and biophysical research communications 2018 Mar 4;497(2):564-570
Biochemical and biophysical research communications 2018 Mar 4;497(2):564-570
7-Acetylsinumaximol B Induces Apoptosis and Autophagy in Human Gastric Carcinoma Cells through Mitochondria Dysfunction and Activation of the PERK/eIF2α/ATF4/CHOP Signaling Pathway.
Tsai TC, Lai KH, Su JH, Wu YJ, Sheu JH
Marine drugs 2018 Mar 26;16(4)
Marine drugs 2018 Mar 26;16(4)
In vitro inhibition of porcine reproductive and respiratory syndrome virus replication by short antisense oligonucleotides with locked nucleic acid modification.
Zhu L, Bi J, Zheng L, Zhao Q, Shu X, Guo G, Liu J, Yang G, Liu J, Yin G
BMC veterinary research 2018 Mar 26;14(1):109
BMC veterinary research 2018 Mar 26;14(1):109
Epidermal Growth Factor, through Alleviating Oxidative Stress, Protect IPEC-J2 Cells from Lipopolysaccharides-Induced Apoptosis.
Tang X, Liu B, Wang X, Yu Q, Fang R
International journal of molecular sciences 2018 Mar 14;19(3)
International journal of molecular sciences 2018 Mar 14;19(3)
Early Postnatal Exposure to Airborne Fine Particulate Matter Induces Autism-like Phenotypes in Male Rats.
Li K, Li L, Cui B, Gai Z, Li Q, Wang S, Yan J, Lin B, Tian L, Liu H, Liu X, Xi Z
Toxicological sciences : an official journal of the Society of Toxicology 2018 Mar 1;162(1):189-199
Toxicological sciences : an official journal of the Society of Toxicology 2018 Mar 1;162(1):189-199
All-Trans Retinoic Acid Ameliorates the Early Experimental Cerebral Ischemia-Reperfusion Injury in Rats by Inhibiting the Loss of the Blood-Brain Barrier via the JNK/P38MAPK Signaling Pathway.
Li M, Tian X, An R, Yang M, Zhang Q, Xiang F, Liu H, Wang Y, Xu L, Dong Z
Neurochemical research 2018 Jun;43(6):1283-1296
Neurochemical research 2018 Jun;43(6):1283-1296
Formononetin inhibits colon carcinoma cell growth and invasion by microRNA‑149‑mediated EphB3 downregulation and inhibition of PI3K/AKT and STAT3 signaling pathways.
Wang AL, Li Y, Zhao Q, Fan LQ
Molecular medicine reports 2018 Jun;17(6):7721-7729
Molecular medicine reports 2018 Jun;17(6):7721-7729
Expression of tumor suppressor programmed cell death 4 in endometrioid endometrial carcinomas and clinicopathological significance.
Liu Y, Sun H, Mao H, Gao M, Tan X, Li Y, Li Y, Muloye GM, Zhang L, Wang X, Wei Z
Oncology letters 2018 Jun;15(6):9369-9376
Oncology letters 2018 Jun;15(6):9369-9376
FPOA induces apoptosis in HeLa human cervical cancer cells through a caspase-mediated pathway.
Li X, Bau T, Bao H
Oncology letters 2018 Jun;15(6):8357-8362
Oncology letters 2018 Jun;15(6):8357-8362
Pseudo-Ginsenoside Rh2 induces A549 cells apoptosis via the Ras/Raf/ERK/p53 pathway.
Wang Y, Xu H, Lu Z, Yu X, Lv C, Tian Y, Sui D
Experimental and therapeutic medicine 2018 Jun;15(6):4916-4924
Experimental and therapeutic medicine 2018 Jun;15(6):4916-4924
Effects of Tumor Necrosis Factor α (TNF-α) and Interleukina 10 (IL-10) on Intercellular Cell Adhesion Molecule-1 (ICAM-1) and Cluster of Differentiation 31 (CD31) in Human Coronary Artery Endothelial Cells.
Xue M, Qiqige C, Zhang Q, Zhao H, Su L, Sun P, Zhao P
Medical science monitor : international medical journal of experimental and clinical research 2018 Jun 27;24:4433-4439
Medical science monitor : international medical journal of experimental and clinical research 2018 Jun 27;24:4433-4439
Chronic cold exposure results in subcutaneous adipose tissue browning and altered global metabolism in Qinghai-Tibetan plateau pika (Ochotona curzoniae).
Li J, Yang Q, Bai Z, Zhou W, Semenza GL, Ge RL
Biochemical and biophysical research communications 2018 Jun 2;500(2):117-123
Biochemical and biophysical research communications 2018 Jun 2;500(2):117-123
Regional up-regulation of NOX2 contributes to the differential vulnerability of outer hair cells to neomycin.
Qi M, Qiu Y, Zhou X, Tian K, Zhou K, Sun F, Yue B, Chen F, Zha D, Qiu J
Biochemical and biophysical research communications 2018 Jun 2;500(2):110-116
Biochemical and biophysical research communications 2018 Jun 2;500(2):110-116
Down-regulation of IFIT3 protects liver from ischemia-reperfusion injury.
Guan G, Shen Y, Yu Q, Liu H, Zhang B, Guo Y, Zhu X, Li Z, Rao W, Zhuang L, Zang Y
International immunopharmacology 2018 Jul;60:170-178
International immunopharmacology 2018 Jul;60:170-178
Long non-coding RNA (lncRNA) MAGI2-AS3 inhibits breast cancer cell growth by targeting the Fas/FasL signalling pathway.
Yang Y, Yang H, Xu M, Zhang H, Sun M, Mu P, Dong T, Du S, Liu K
Human cell 2018 Jul;31(3):232-241
Human cell 2018 Jul;31(3):232-241
Wnt/β-catenin modulates chronic tobacco smoke exposure-induced acquisition of pulmonary cancer stem cell properties and diallyl trisulfide intervention.
Wang J, Chen J, Jiang Y, Shi Y, Zhu J, Xie C, Geng S, Wu J, Zhang Q, Wang X, Meng Y, Li Y, Chen Y, Cao W, Wang X, Zhong C, Li X
Toxicology letters 2018 Jul;291:70-76
Toxicology letters 2018 Jul;291:70-76
Glutathione Reduction of Patulin-Evoked Cytotoxicity in HEK293 Cells by the Prevention of Oxidative Damage and the Mitochondrial Apoptotic Pathway.
Wang X, Jin C, Zhong Y, Li X, Han J, Xue W, Wu P, Xia X, Peng X
Journal of agricultural and food chemistry 2018 Jul 25;66(29):7775-7785
Journal of agricultural and food chemistry 2018 Jul 25;66(29):7775-7785
Intermittent streptozotocin administration induces behavioral and pathological features relevant to Alzheimer's disease and vascular dementia.
Murtishaw AS, Heaney CF, Bolton MM, Belmonte KCD, Langhardt MA, Kinney JW
Neuropharmacology 2018 Jul 15;137:164-177
Neuropharmacology 2018 Jul 15;137:164-177
Baicalein inhibits cervical cancer progression via downregulating long noncoding RNA BDLNR and its downstream PI3K/Akt pathway.
Yu X, Yang Y, Li Y, Cao Y, Tang L, Chen F, Xia J
The international journal of biochemistry & cell biology 2018 Jan;94:107-118
The international journal of biochemistry & cell biology 2018 Jan;94:107-118
Activation of Nrf2 pathway and inhibition of NLRP3 inflammasome activation contribute to the protective effect of chlorogenic acid on acute liver injury.
Shi A, Shi H, Wang Y, Liu X, Cheng Y, Li H, Zhao H, Wang S, Dong L
International immunopharmacology 2018 Jan;54:125-130
International immunopharmacology 2018 Jan;54:125-130
Nitric oxide, afferent sensory nerves, and antioxidative enzymes in the mechanism of protection mediated by tricarbonyldichlororuthenium(II) dimer and sodium hydrosulfide against aspirin-induced gastric damage.
Magierowski M, Hubalewska-Mazgaj M, Magierowska K, Wojcik D, Sliwowski Z, Kwiecien S, Brzozowski T
Journal of gastroenterology 2018 Jan;53(1):52-63
Journal of gastroenterology 2018 Jan;53(1):52-63
Anticancer effect of SZC015 on pancreatic cancer via mitochondria-dependent apoptosis and the constitutive suppression of activated nuclear factor κB and STAT3 in vitro and in vivo.
Song Y, Gao L, Tang Z, Li H, Sun B, Chu P, Qaed E, Ma X, Peng J, Wang S, Hu M, Tang Z
Journal of cellular physiology 2018 Jan;234(1):777-788
Journal of cellular physiology 2018 Jan;234(1):777-788
Thrombopoietin protects H9C2 cells from excessive autophagy and apoptosis in doxorubicin-induced cardiotoxicity.
Wang H, Wang H, Liang EY, Zhou LX, Dong ZL, Liang P, Weng QF, Yang M
Oncology letters 2018 Jan;15(1):839-848
Oncology letters 2018 Jan;15(1):839-848
Exogenous oxidants activate nuclear factor kappa B through Toll-like receptor 4 stimulation to maintain inflammatory phenotype in macrophage.
Zhang Y, Igwe OJ
Biochemical pharmacology 2018 Jan;147:104-118
Biochemical pharmacology 2018 Jan;147:104-118
Experimental evidence of good efficacy and reduced toxicity with peptide-doxorubicin to treat gastric cancer.
Zhang J, Yuan JP, Wang Q, Shao LH, Liu SP, Firestone RA, Hong YP, Li JG, Xin YC, Li Y
Oncotarget 2018 Jan 5;9(2):1957-1968
Oncotarget 2018 Jan 5;9(2):1957-1968
The protective role of low-concentration alcohol in high-fructose induced adverse cardiovascular events in mice.
Wu X, Pan B, Wang Y, Liu L, Huang X, Tian J
Biochemical and biophysical research communications 2018 Jan 1;495(1):1403-1410
Biochemical and biophysical research communications 2018 Jan 1;495(1):1403-1410
Nicotine Induces Progressive Properties of Lung Adenocarcinoma A549 Cells by Inhibiting Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Expression and Plasma Membrane Localization.
Li H, Ma N, Wang J, Wang Y, Yuan C, Wu J, Luo M, Yang J, Chen J, Shi J, Liu X
Technology in cancer research & treatment 2018 Jan 1;17:1533033818809984
Technology in cancer research & treatment 2018 Jan 1;17:1533033818809984
Effects of calycosin against high-fat diet-induced nonalcoholic fatty liver disease in mice.
Duan X, Meng Q, Wang C, Liu Z, Sun H, Huo X, Sun P, Ma X, Peng J, Liu K
Journal of gastroenterology and hepatology 2018 Feb;33(2):533-542
Journal of gastroenterology and hepatology 2018 Feb;33(2):533-542
Genipin alleviates high-fat diet-induced hyperlipidemia and hepatic lipid accumulation in mice via miR-142a-5p/SREBP-1c axis.
Zhong H, Chen K, Feng M, Shao W, Wu J, Chen K, Liang T, Liu C
The FEBS journal 2018 Feb;285(3):501-517
The FEBS journal 2018 Feb;285(3):501-517
Di-(2-ethylhexyl)-phthalate induces glucose metabolic disorder in adolescent rats.
Xu J, Zhou L, Wang S, Zhu J, Liu T, Jia Y, Sun D, Chen H, Wang Q, Xu F, Zhang Y, Liu H, Zhang T, Ye L
Environmental science and pollution research international 2018 Feb;25(4):3596-3607
Environmental science and pollution research international 2018 Feb;25(4):3596-3607
Construction and protective immunogenicity of DNA vaccine pNMB0315 against Neisseria meningitidis serogroup B.
Wu X, Li K, Xie M, Yu M, Tang S, Li Z, Hu S
Molecular medicine reports 2018 Feb;17(2):3178-3185
Molecular medicine reports 2018 Feb;17(2):3178-3185
The N-terminal ubiquitin-associated domain of Cezanne is crucial for its function to suppress NF-κB pathway.
Ji Y, Cao L, Zeng L, Zhang Z, Xiao Q, Guan P, Chen S, Chen Y, Wang M, Guo D
Journal of cellular biochemistry 2018 Feb;119(2):1979-1991
Journal of cellular biochemistry 2018 Feb;119(2):1979-1991
[Impact of Cystic Fibrosis Transmembrane Conductance Regulator on Malignant Properties of KRAS Mutant Lung Adenocarcinoma A549 Cells].
Li H, Wang Y, Yang J, Liu X, Shi J
Zhongguo fei ai za zhi = Chinese journal of lung cancer 2018 Feb 20;21(2):89-98
Zhongguo fei ai za zhi = Chinese journal of lung cancer 2018 Feb 20;21(2):89-98
RACK1 is indispensable for porcine reproductive and respiratory syndrome virus replication and NF-κB activation in Marc-145 cells.
Bi J, Zhao Q, Zhu L, Li X, Yang G, Liu J, Yin G
Scientific reports 2018 Feb 14;8(1):2985
Scientific reports 2018 Feb 14;8(1):2985
Neuroprotective Effect of Anethole Against Neuropathic Pain Induced by Chronic Constriction Injury of the Sciatic Nerve in Mice.
Wang B, Zhang G, Yang M, Liu N, Li YX, Ma H, Ma L, Sun T, Tan H, Yu J
Neurochemical research 2018 Dec;43(12):2404-2422
Neurochemical research 2018 Dec;43(12):2404-2422
Relationship of Epidermal Growth Factor Receptor Expression with Clinical Symptoms and Metastasis of Invasive Breast Cancer.
Han L, Li L, Wang N, Xiong Y, Li Y, Gu Y
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2018 Dec;38(12):578-582
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2018 Dec;38(12):578-582
Role of Long Noncoding RNA 799 in the Metastasis of Cervical Cancer through Upregulation of TBL1XR1 Expression.
Liao LM, Zhang FH, Yao GJ, Ai SF, Zheng M, Huang L
Molecular therapy. Nucleic acids 2018 Dec 7;13:580-589
Molecular therapy. Nucleic acids 2018 Dec 7;13:580-589
WISP1 mediates lung injury following hepatic ischemia reperfusion dependent on TLR4 in mice.
Tong Y, Yu Z, Zhang R, Ding X, Chen Z, Li Q
BMC pulmonary medicine 2018 Dec 6;18(1):189
BMC pulmonary medicine 2018 Dec 6;18(1):189
The Traditional Chinese Medicine MLC901 inhibits inflammation processes after focal cerebral ischemia.
Widmann C, Gandin C, Petit-Paitel A, Lazdunski M, Heurteaux C
Scientific reports 2018 Dec 24;8(1):18062
Scientific reports 2018 Dec 24;8(1):18062
Cancer-derived exosomal miR-25-3p promotes pre-metastatic niche formation by inducing vascular permeability and angiogenesis.
Zeng Z, Li Y, Pan Y, Lan X, Song F, Sun J, Zhou K, Liu X, Ren X, Wang F, Hu J, Zhu X, Yang W, Liao W, Li G, Ding Y, Liang L
Nature communications 2018 Dec 19;9(1):5395
Nature communications 2018 Dec 19;9(1):5395
Metformin suppresses growth and adrenocorticotrophic hormone secretion in mouse pituitary corticotroph tumor AtT20 cells.
Jin K, Ruan L, Pu J, Zhong A, Wang F, Tan S, Huang H, Mu J, Yang G
Molecular and cellular endocrinology 2018 Dec 15;478:53-61
Molecular and cellular endocrinology 2018 Dec 15;478:53-61
Whole-exome sequencing revealed HKDC1 as a candidate gene associated with autosomal-recessive retinitis pigmentosa.
Zhang L, Sun Z, Zhao P, Huang L, Xu M, Yang Y, Chen X, Lu F, Zhang X, Wang H, Zhang S, Liu W, Jiang Z, Ma S, Chen R, Zhao C, Yang Z, Sui R, Zhu X
Human molecular genetics 2018 Dec 1;27(23):4157-4168
Human molecular genetics 2018 Dec 1;27(23):4157-4168
Transcription Factor FOXO3a Is a Negative Regulator of Cytotoxicity of Fusarium mycotoxin in GES-1 Cells.
Yang Y, Yu S, Liu N, Xu H, Gong Y, Wu Y, Wang P, Su X, Liao Y, De Saeger S, Humpf HU, Wu A
Toxicological sciences : an official journal of the Society of Toxicology 2018 Dec 1;166(2):370-381
Toxicological sciences : an official journal of the Society of Toxicology 2018 Dec 1;166(2):370-381
Protective effects of ginsenoside Rg1 against lipopolysaccharide/d-galactosamine-induced acute liver injury in mice through inhibiting toll-like receptor 4 signaling pathway.
Ning C, Gao X, Wang C, Huo X, Liu Z, Sun H, Yang X, Sun P, Ma X, Meng Q, Liu K
International immunopharmacology 2018 Aug;61:266-276
International immunopharmacology 2018 Aug;61:266-276
Dietary eicosapentaenoic acid normalizes hippocampal omega-3 and 6 polyunsaturated fatty acid profile, attenuates glial activation and regulates BDNF function in a rodent model of neuroinflammation induced by central interleukin-1β administration.
Dong Y, Xu M, Kalueff AV, Song C
European journal of nutrition 2018 Aug;57(5):1781-1791
European journal of nutrition 2018 Aug;57(5):1781-1791
TRPC1/3/6 inhibition attenuates the TGF-β1-induced epithelial-mesenchymal transition in gastric cancer via the Ras/Raf1/ERK signaling pathway.
Ge P, Wei L, Zhang M, Hu B, Wang K, Li Y, Liu S, Wang J, Li Y
Cell biology international 2018 Aug;42(8):975-984
Cell biology international 2018 Aug;42(8):975-984
Knockdown of TIPE2 increases the proliferation in lipopolysaccharide-stimulated gastric cancer cells.
Liu W, Fan Y, Shi Y, Lin Z, Huang X, Huang W, Shen D, Qi Z
BMC cancer 2018 Aug 29;18(1):857
BMC cancer 2018 Aug 29;18(1):857
Anti-inflammatory activities and potential mechanisms of phenolic acids isolated from Salvia miltiorrhiza f. alba roots in THP-1 macrophages.
Liu H, Ma S, Xia H, Lou H, Zhu F, Sun L
Journal of ethnopharmacology 2018 Aug 10;222:201-207
Journal of ethnopharmacology 2018 Aug 10;222:201-207
Hepatic, Metabolic, and Toxicity Evaluation of Repeated Oral Administration of SnS2 Nanoflowers in Mice.
Bai D, Li Q, Xiong Y, Wang C, Shen P, Bai L, Yuan L, Wu P
Toxicological sciences : an official journal of the Society of Toxicology 2018 Aug 1;164(2):501-511
Toxicological sciences : an official journal of the Society of Toxicology 2018 Aug 1;164(2):501-511
Aspm knockout ferret reveals an evolutionary mechanism governing cerebral cortical size.
Johnson MB, Sun X, Kodani A, Borges-Monroy R, Girskis KM, Ryu SC, Wang PP, Patel K, Gonzalez DM, Woo YM, Yan Z, Liang B, Smith RS, Chatterjee M, Coman D, Papademetris X, Staib LH, Hyder F, Mandeville JB, Grant PE, Im K, Kwak H, Engelhardt JF, Walsh CA, Bae BI
Nature 2018 Apr;556(7701):370-375
Nature 2018 Apr;556(7701):370-375
CHOP induces apoptosis by affecting brain iron metabolism in rats with subarachnoid hemorrhage.
Zhao J, Xiang X, Zhang H, Jiang D, Liang Y, Qing W, Liu L, Zhao Q, He Z
Experimental neurology 2018 Apr;302:22-33
Experimental neurology 2018 Apr;302:22-33
Regulation on SIRT1-PGC-1α/Nrf2 pathway together with selective inhibition of aldose reductase makes compound hr5F a potential agent for the treatment of diabetic complications.
Wang Z, Yuan S, Li Y, Zhang Z, Xiao W, Tang D, Ye K, Liu Z, Wang C, Zheng Y, Nie H, Chen H
Biochemical pharmacology 2018 Apr;150:54-63
Biochemical pharmacology 2018 Apr;150:54-63
DL-3-n-butylphthalide alleviates vascular cognitive impairment induced by chronic cerebral hypoperfusion by activating the Akt/Nrf2 signaling pathway in the hippocampus of rats.
Qi Q, Xu J, Lv P, Dong Y, Liu Z, Hu M, Xiao Y, Jia Y, Jin W, Fan M, Zhang D, Meng N
Neuroscience letters 2018 Apr 13;672:59-64
Neuroscience letters 2018 Apr 13;672:59-64
Novel decellularized liver matrix-alginate hybrid gel beads for the 3D culture of hepatocellular carcinoma cells.
Sun D, Liu Y, Wang H, Deng F, Zhang Y, Zhao S, Ma X, Wu H, Sun G
International journal of biological macromolecules 2018 Apr 1;109:1154-1163
International journal of biological macromolecules 2018 Apr 1;109:1154-1163
Volatile Oil from Amomi Fructus Attenuates 5-Fluorouracil-Induced Intestinal Mucositis.
Zhang T, Lu SH, Bi Q, Liang L, Wang YF, Yang XX, Gu W, Yu J
Frontiers in pharmacology 2017;8:786
Frontiers in pharmacology 2017;8:786
Inhibition of the TRPM2 and TRPV1 Channels through Hypericum perforatum in Sciatic Nerve Injury-induced Rats Demonstrates their Key Role in Apoptosis and Mitochondrial Oxidative Stress of Sciatic Nerve and Dorsal Root Ganglion.
Uslusoy F, Nazıroğlu M, Çiğ B
Frontiers in physiology 2017;8:335
Frontiers in physiology 2017;8:335
Whole exome-wide association study identifies a missense variant in SLC2A4RG associated with glioblastoma risk.
Zhao Y, Yun D, Zou X, Jiang T, Li G, Hu L, Chen J, Xu J, Mao Y, Chen H, Lu D
American journal of cancer research 2017;7(9):1937-1947
American journal of cancer research 2017;7(9):1937-1947
Inhibition of HIF-1α by PX-478 suppresses tumor growth of esophageal squamous cell cancer in vitro and in vivo.
Zhu Y, Zang Y, Zhao F, Li Z, Zhang J, Fang L, Li M, Xing L, Xu Z, Yu J
American journal of cancer research 2017;7(5):1198-1212
American journal of cancer research 2017;7(5):1198-1212
Rosiglitazone Inhibits Angiotensin II-Induced Proliferation of Glomerular Mesangial Cells via the Gαq/Plcβ4/TRPC Signaling Pathway.
Wei L, Mao J, Lu J, Gao J, Zhu D, Tian L, Chen Z, Jia L, Wang L, Fu R
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;44(6):2228-2242
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;44(6):2228-2242
Chondroprotective Effects and Multitarget Mechanisms of Fu Yuan Capsule in a Rat Osteoarthritis Model.
Zeng L, Xiao CZ, Deng ZT, Li RH
Evidence-based complementary and alternative medicine : eCAM 2017;2017:8985623
Evidence-based complementary and alternative medicine : eCAM 2017;2017:8985623
Electroacupuncture Improved Hippocampal Neurogenesis following Traumatic Brain Injury in Mice through Inhibition of TLR4 Signaling Pathway.
Ye Y, Yang Y, Chen C, Li Z, Jia Y, Su X, Wang C, He X
Stem cells international 2017;2017:5841814
Stem cells international 2017;2017:5841814
Pretreatment Donors after Circulatory Death with Simvastatin Alleviates Liver Ischemia Reperfusion Injury through a KLF2-Dependent Mechanism in Rat.
Liu Z, Zhang X, Xiao Q, Ye S, Lai CH, Luo J, Huang X, Wang W, Zeng C, Zhong Z, Fan X, Xia Z, Xiong Y, Mao X, Ye Q, Wang Y
Oxidative medicine and cellular longevity 2017;2017:3861914
Oxidative medicine and cellular longevity 2017;2017:3861914
Differential inhibition of activity, activation and gene expression of MMP-9 in THP-1 cells by azithromycin and minocycline versus bortezomib: A comparative study.
Vandooren J, Knoops S, Aldinucci Buzzo JL, Boon L, Martens E, Opdenakker G, Kolaczkowska E
PloS one 2017;12(4):e0174853
PloS one 2017;12(4):e0174853
Hyperlipidemia impairs erectile function in rats by causing cavernosal fibrosis.
Li R, Cui K, Wang T, Wang S, Li X, Qiu J, Yu G, Liu J, Wen B, Rao K
Andrologia 2017 Sep;49(7)
Andrologia 2017 Sep;49(7)
Histone variant H3.3 orchestrates neural stem cell differentiation in the developing brain.
Xia W, Jiao J
Cell death and differentiation 2017 Sep;24(9):1548-1563
Cell death and differentiation 2017 Sep;24(9):1548-1563
Exosomes derived from bone marrow stromal cells decrease the sensitivity of leukemic cells to etoposide.
Wang J, Li D, Zhuang Y, Fu J, Li X, Shi Q, Ju X
Oncology letters 2017 Sep;14(3):3082-3088
Oncology letters 2017 Sep;14(3):3082-3088
Roux-en-Y gastric bypass surgery suppresses hypothalamic PTP1B protein level and alleviates leptin resistance in obese rats.
Liu JY, Mu S, Zhang SP, Guo W, Li QF, Xiao XQ, Zhang J, Wang ZH
Experimental and therapeutic medicine 2017 Sep;14(3):2536-2542
Experimental and therapeutic medicine 2017 Sep;14(3):2536-2542
Low Frequency Magnetic Fields Induce Autophagy-associated Cell Death in Lung Cancer through miR-486-mediated Inhibition of Akt/mTOR Signaling Pathway.
Xu Y, Wang Y, Yao A, Xu Z, Dou H, Shen S, Hou Y, Wang T
Scientific reports 2017 Sep 18;7(1):11776
Scientific reports 2017 Sep 18;7(1):11776
AMPK activation-dependent autophagy compromises oleanolic acid-induced cytotoxicity in human bladder cancer cells.
Song Y, Zhang P, Sun Y, Li X, Chen L, Xiao Y, Xing Y
Oncotarget 2017 Sep 15;8(40):67942-67954
Oncotarget 2017 Sep 15;8(40):67942-67954
Role of autophagy in cadmium-induced testicular injury.
Wang YJ, Yan J, Yin F, Li L, Qin YG, Meng CY, Lu RF, Guo L
Human & experimental toxicology 2017 Oct;36(10):1039-1048
Human & experimental toxicology 2017 Oct;36(10):1039-1048
Effects of hydrogen sulfide on inducible nitric oxide synthase activity and expression of cardiomyocytes in diabetic rats.
Yang R, Jia Q, Liu XF, Wang YY, Ma SF
Molecular medicine reports 2017 Oct;16(4):5277-5284
Molecular medicine reports 2017 Oct;16(4):5277-5284
Antiplatelet drug ticagrelor delays gastric ulcer healing in rats.
Li JJ, Wu XY, Chen JL, Chen GR, Xu J, Gu Y, Song HP
Experimental and therapeutic medicine 2017 Oct;14(4):3774-3779
Experimental and therapeutic medicine 2017 Oct;14(4):3774-3779
HOTAIR regulates HK2 expression by binding endogenous miR-125 and miR-143 in oesophageal squamous cell carcinoma progression.
Ma J, Fan Y, Feng T, Chen F, Xu Z, Li S, Lin Q, He X, Shi W, Liu Y, Liu Z, Zhu B, Cao X
Oncotarget 2017 Oct 17;8(49):86410-86422
Oncotarget 2017 Oct 17;8(49):86410-86422
Functional characterization of a novel transcript of ERCC1 in chemotherapy resistance of ovarian cancer.
Liu J, Zhang L, Mao P, Jiang G, Liu L, Wang J, Yang W, Owusu L, Li W
Oncotarget 2017 Oct 17;8(49):85759-85771
Oncotarget 2017 Oct 17;8(49):85759-85771
A novel protein derived from lamprey supraneural body tissue with efficient cytocidal actions against tumor cells.
Pang Y, Li C, Wang S, Ba W, Yu T, Pei G, Bi D, Liang H, Pan X, Zhu T, Gou M, Han Y, Li Q
Cell communication and signaling : CCS 2017 Oct 16;15(1):42
Cell communication and signaling : CCS 2017 Oct 16;15(1):42
LINC00461, a long non-coding RNA, is important for the proliferation and migration of glioma cells.
Yang Y, Ren M, Song C, Li D, Soomro SH, Xiong Y, Zhang H, Fu H
Oncotarget 2017 Oct 13;8(48):84123-84139
Oncotarget 2017 Oct 13;8(48):84123-84139
A high-fat, high-protein diet attenuates the negative impact of casein-induced chronic inflammation on testicular steroidogenesis and sperm parameters in adult mice.
Zhao JL, Zhao YY, Zhu WJ
General and comparative endocrinology 2017 Oct 1;252:48-59
General and comparative endocrinology 2017 Oct 1;252:48-59
Neuroprotective effect of liquiritin against neuropathic pain induced by chronic constriction injury of the sciatic nerve in mice.
Zhang MT, Wang B, Jia YN, Liu N, Ma PS, Gong SS, Niu Y, Sun T, Li YX, Yu JQ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Nov;95:186-198
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Nov;95:186-198
Hepatoprotective effect of quercetin against LPS/d-GalN induced acute liver injury in mice by inhibiting the IKK/NF-κB and MAPK signal pathways.
Peng Z, Gong X, Yang Y, Huang L, Zhang Q, Zhang P, Wan R, Zhang B
International immunopharmacology 2017 Nov;52:281-289
International immunopharmacology 2017 Nov;52:281-289
Neuroprotective Effect of Chitosan Oligosaccharide on Hypoxic-Ischemic Brain Damage in Neonatal Rats.
Wu W, Wei W, Lu M, Zhu X, Liu N, Niu Y, Sun T, Li Y, Yu J
Neurochemical research 2017 Nov;42(11):3186-3198
Neurochemical research 2017 Nov;42(11):3186-3198
CMIP is oncogenic in human gastric cancer cells.
Zhang J, Huang J, Wang X, Chen W, Tang Q, Fang M, Qian Y
Molecular medicine reports 2017 Nov;16(5):7277-7286
Molecular medicine reports 2017 Nov;16(5):7277-7286
Dlitiazem inhibits the oxidative stress induced by angiotensin II through growth hormone secretagogue receptor type 1a in human umbilicus vein endothelial cells.
Zhou L, Yang M, Zuo S, Guan X, Wang J, Chen Q, Zuo X, Jia S, Guo R
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 May;89:76-82
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 May;89:76-82
Protective effects of aloperine on monocrotaline-induced pulmonary hypertension in rats.
Wu F, Hao Y, Yang J, Yao W, Xu Y, Yan L, Niu Y, Sun T, Yu J, Zhou R
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 May;89:632-641
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 May;89:632-641
ApoA-I/SR-BI modulates S1P/S1PR2-mediated inflammation through the PI3K/Akt signaling pathway in HUVECs.
Ren K, Lu YJ, Mo ZC, -Liu X, Tang ZL, Jiang Y, Peng XS, Li L, Zhang QH, Yi GH
Journal of physiology and biochemistry 2017 May;73(2):287-296
Journal of physiology and biochemistry 2017 May;73(2):287-296
Up-regulated BAFF and BAFF receptor expression in patients with intractable temporal lobe epilepsy and a pilocarpine-induced epilepsy rat model.
Ma L, Li R, Huang H, Yuan J, Ou S, Xu T, Yu X, Liu X, Chen Y
Seizure 2017 May;48:79-88
Seizure 2017 May;48:79-88
β-Caryophyllene Pretreatment Alleviates Focal Cerebral Ischemia-Reperfusion Injury by Activating PI3K/Akt Signaling Pathway.
Zhang Q, An R, Tian X, Yang M, Li M, Lou J, Xu L, Dong Z
Neurochemical research 2017 May;42(5):1459-1469
Neurochemical research 2017 May;42(5):1459-1469
AGR2 ameliorates tumor necrosis factor-α-induced epithelial barrier dysfunction via suppression of NF-κB p65-mediated MLCK/p-MLC pathway activation.
Ye X, Sun M
International journal of molecular medicine 2017 May;39(5):1206-1214
International journal of molecular medicine 2017 May;39(5):1206-1214
Relationship between abnormal TOX3 gene methylation and polycystic ovarian syndrome.
Ning Z, Jiayi L, Jian R, Wanli X
European review for medical and pharmacological sciences 2017 May;21(9):2034-2038
European review for medical and pharmacological sciences 2017 May;21(9):2034-2038
Icariin inhibits MMP‑1, MMP‑3 and MMP‑13 expression through MAPK pathways in IL‑1β‑stimulated SW1353 chondrosarcoma cells.
Zeng L, Rong XF, Li RH, Wu XY
Molecular medicine reports 2017 May;15(5):2853-2858
Molecular medicine reports 2017 May;15(5):2853-2858
A novel role of fragile X mental retardation protein in pre-mRNA alternative splicing through RNA-binding protein 14.
Zhou LT, Ye SH, Yang HX, Zhou YT, Zhao QH, Sun WW, Gao MM, Yi YH, Long YS
Neuroscience 2017 May 4;349:64-75
Neuroscience 2017 May 4;349:64-75
PLAA Mutations Cause a Lethal Infantile Epileptic Encephalopathy by Disrupting Ubiquitin-Mediated Endolysosomal Degradation of Synaptic Proteins.
Hall EA, Nahorski MS, Murray LM, Shaheen R, Perkins E, Dissanayake KN, Kristaryanto Y, Jones RA, Vogt J, Rivagorda M, Handley MT, Mali GR, Quidwai T, Soares DC, Keighren MA, McKie L, Mort RL, Gammoh N, Garcia-Munoz A, Davey T, Vermeren M, Walsh D, Budd P, Aligianis IA, Faqeih E, Quigley AJ, Jackson IJ, Kulathu Y, Jackson M, Ribchester RR, von Kriegsheim A, Alkuraya FS, Woods CG, Maher ER, Mill P
American journal of human genetics 2017 May 4;100(5):706-724
American journal of human genetics 2017 May 4;100(5):706-724
The Long Noncoding RNA NEAT1 Exerts Antihantaviral Effects by Acting as Positive Feedback for RIG-I Signaling.
Ma H, Han P, Ye W, Chen H, Zheng X, Cheng L, Zhang L, Yu L, Wu X, Xu Z, Lei Y, Zhang F
Journal of virology 2017 May 1;91(9)
Journal of virology 2017 May 1;91(9)
The Anticonvulsant and Neuroprotective Effects of Oxysophocarpine on Pilocarpine-Induced Convulsions in Adult Male Mice.
Liu G, Wang J, Deng XH, Ma PS, Li FM, Peng XD, Niu Y, Sun T, Li YX, Yu JQ
Cellular and molecular neurobiology 2017 Mar;37(2):339-349
Cellular and molecular neurobiology 2017 Mar;37(2):339-349
KIAA1199 is induced by inflammation and enhances malignant phenotype in pancreatic cancer.
Kohi S, Sato N, Koga A, Matayoshi N, Hirata K
Oncotarget 2017 Mar 7;8(10):17156-17163
Oncotarget 2017 Mar 7;8(10):17156-17163
Generation and characteristics of human Sertoli cell line immortalized by overexpression of human telomerase.
Wen L, Yuan Q, Sun M, Niu M, Wang H, Fu H, Zhou F, Yao C, Wang X, Li Z, He Z
Oncotarget 2017 Mar 7;8(10):16553-16570
Oncotarget 2017 Mar 7;8(10):16553-16570
Beneficial effects of Lycium barbarum polysaccharide on spermatogenesis by improving antioxidant activity and inhibiting apoptosis in streptozotocin-induced diabetic male mice.
Shi GJ, Zheng J, Wu J, Qiao HQ, Chang Q, Niu Y, Sun T, Li YX, Yu JQ
Food & function 2017 Mar 22;8(3):1215-1226
Food & function 2017 Mar 22;8(3):1215-1226
Mitochondrial dynamics changes with age in an APPsw/PS1dE9 mouse model of Alzheimer's disease.
Xu LL, Shen Y, Wang X, Wei LF, Wang P, Yang H, Wang CF, Xie ZH, Bi JZ
Neuroreport 2017 Mar 1;28(4):222-228
Neuroreport 2017 Mar 1;28(4):222-228
HMGB1-induced autophagy: a new pathway to maintain Treg function during chronic hepatitis B virus infection.
Cheng LS, Li J, Liu Y, Wang FP, Wang SQ, She WM, Wu SD, Qi XL, Zhou YP, Jiang W
Clinical science (London, England : 1979) 2017 Mar 1;131(5):381-394
Clinical science (London, England : 1979) 2017 Mar 1;131(5):381-394
TGF-β1 promotes human hepatic carcinoma HepG2 cells invasion by upregulating autophagy.
Ma CL, Qiao S, Li YC, Wang XF, Sun RJ, Zhang X, Qian RK, Song SD
European review for medical and pharmacological sciences 2017 Jun;21(11):2604-2610
European review for medical and pharmacological sciences 2017 Jun;21(11):2604-2610
DDX50 inhibits the replication of dengue virus 2 by upregulating IFN-β production.
Han P, Ye W, Lv X, Ma H, Weng D, Dong Y, Cheng L, Chen H, Zhang L, Xu Z, Lei Y, Zhang F
Archives of virology 2017 Jun;162(6):1487-1494
Archives of virology 2017 Jun;162(6):1487-1494
Generation and characterization of induced pluripotent stem cells from guinea pig fetal fibroblasts.
Wu Y, Li O, He C, Li Y, Li M, Liu XL, Wang Y, He Y
Molecular medicine reports 2017 Jun;15(6):3690-3698
Molecular medicine reports 2017 Jun;15(6):3690-3698
Esculetin induces apoptosis of SMMC-7721 cells through IGF-1/PI3K/Akt-mediated mitochondrial pathways.
Li J, Li S, Wang X, Wang H
Canadian journal of physiology and pharmacology 2017 Jul;95(7):787-794
Canadian journal of physiology and pharmacology 2017 Jul;95(7):787-794
Estrogen receptor-α36 is involved in icaritin induced growth inhibition of triple-negative breast cancer cells.
Wang X, Zheng N, Dong J, Wang X, Liu L, Huang J
The Journal of steroid biochemistry and molecular biology 2017 Jul;171:318-327
The Journal of steroid biochemistry and molecular biology 2017 Jul;171:318-327
Nrf2-Knockout Protects from Intestinal Injuries in C57BL/6J Mice Following Abdominal Irradiation with γ Rays.
Yang W, Sun Z, Yang B, Wang Q
International journal of molecular sciences 2017 Jul 31;18(8)
International journal of molecular sciences 2017 Jul 31;18(8)
Hypoxia-inducible factor-1 alpha is involved in RIP-induced necroptosis caused by in vitro and in vivo ischemic brain injury.
Yang XS, Yi TL, Zhang S, Xu ZW, Yu ZQ, Sun HT, Yang C, Tu Y, Cheng SX
Scientific reports 2017 Jul 19;7(1):5818
Scientific reports 2017 Jul 19;7(1):5818
SHIP, a novel factor to ameliorate extracellular matrix accumulation via suppressing PI3K/Akt/CTGF signaling in diabetic kidney disease.
Li F, Li L, Cheng M, Wang X, Hao J, Liu S, Duan H
Biochemical and biophysical research communications 2017 Jan 22;482(4):1477-1483
Biochemical and biophysical research communications 2017 Jan 22;482(4):1477-1483
Effect of Oleracein E, a Neuroprotective Tetrahydroisoquinoline, on Rotenone-Induced Parkinson's Disease Cell and Animal Models.
Sun H, He X, Liu C, Li L, Zhou R, Jin T, Yue S, Feng D, Gong J, Sun J, Ji J, Xiang L
ACS chemical neuroscience 2017 Jan 18;8(1):155-164
ACS chemical neuroscience 2017 Jan 18;8(1):155-164
BMP4 promotes mouse iPS cell differentiation to male germ cells via Smad1/5, Gata4, Id1 and Id2.
Yang S, Yuan Q, Niu M, Hou J, Zhu Z, Sun M, Li Z, He Z
Reproduction (Cambridge, England) 2017 Feb;153(2):211-220
Reproduction (Cambridge, England) 2017 Feb;153(2):211-220
Induction of apoptosis by FFJ-5, a novel naphthoquinone compound, occurs via downregulation of PKM2 in A549 and HepG2 cells.
Wei X, Li M, Ma M, Jia H, Zhang Y, Kang W, Wang T, Shi X
Oncology letters 2017 Feb;13(2):791-799
Oncology letters 2017 Feb;13(2):791-799
Coptisine from Rhizoma Coptidis Suppresses HCT-116 Cells-related Tumor Growth in vitro and in vivo.
Huang T, Xiao Y, Yi L, Li L, Wang M, Tian C, Ma H, He K, Wang Y, Han B, Ye X, Li X
Scientific reports 2017 Feb 6;7:38524
Scientific reports 2017 Feb 6;7:38524
TRIM14 regulates cell proliferation and invasion in osteosarcoma via promotion of the AKT signaling pathway.
Xu G, Guo Y, Xu D, Wang Y, Shen Y, Wang F, Lv Y, Song F, Jiang D, Zhang Y, Lou Y, Meng Y, Yang Y, Kang Y
Scientific reports 2017 Feb 16;7:42411
Scientific reports 2017 Feb 16;7:42411
Antitumor effects of baicalin on ovarian cancer cells through induction of cell apoptosis and inhibition of cell migration in vitro.
Gao C, Zhou Y, Li H, Cong X, Jiang Z, Wang X, Cao R, Tian W
Molecular medicine reports 2017 Dec;16(6):8729-8734
Molecular medicine reports 2017 Dec;16(6):8729-8734
Chloroform extract of Hedyotis diffusa Willd inhibits viability of human colorectal cancer cells via suppression of AKT and ERK signaling pathways.
Yan Z, Feng J, Peng J, Lai Z, Zhang L, Jin Y, Yang H, Chen W, Lin J
Oncology letters 2017 Dec;14(6):7923-7930
Oncology letters 2017 Dec;14(6):7923-7930
Inhibition of chemotherapy-induced apoptosis of testicular cells by squid ink polysaccharide.
Gu YP, Yang XM, Duan ZH, Luo P, Shang JH, Xiao W, Tao YX, Zhang DY, Zhang YB, Liu HZ
Experimental and therapeutic medicine 2017 Dec;14(6):5889-5895
Experimental and therapeutic medicine 2017 Dec;14(6):5889-5895
Involvement of TRPM2 and TRPV1 channels on hyperalgesia, apoptosis and oxidative stress in rat fibromyalgia model: Protective role of selenium.
Yüksel E, Nazıroğlu M, Şahin M, Çiğ B
Scientific reports 2017 Dec 13;7(1):17543
Scientific reports 2017 Dec 13;7(1):17543
Inhibition of Calcineurin A by FK506 Suppresses Seizures and Reduces the Expression of GluN2B in Membrane Fraction.
Wen Y, Fu P, Wu K, Si K, Xie Y, Dan W, Zhan Y, Shi Q
Neurochemical research 2017 Aug;42(8):2154-2166
Neurochemical research 2017 Aug;42(8):2154-2166
miR-367 promotes tumor growth by inhibiting FBXW7 in NSCLC.
Xiao G, Gao X, Sun X, Yang C, Zhang B, Sun R, Huang G, Li X, Liu J, Du N, Liu D, Liang R, Ren H, Qin S
Oncology reports 2017 Aug;38(2):1190-1198
Oncology reports 2017 Aug;38(2):1190-1198
Melatonin ameliorates restraint stress-induced oxidative stress and apoptosis in testicular cells via NF-κB/iNOS and Nrf2/ HO-1 signaling pathway.
Guo Y, Sun J, Li T, Zhang Q, Bu S, Wang Q, Lai D
Scientific reports 2017 Aug 29;7(1):9599
Scientific reports 2017 Aug 29;7(1):9599
Epigallocatechin-3-gallate inhibits H2O2-induced apoptosis in Mouse Vascular Smooth Muscle Cells via 67kD Laminin Receptor.
Yan X, Li Y, Yu H, Wang W, Wu C, Yang Y, Hu Y, Shi X, Li J
Scientific reports 2017 Aug 10;7(1):7774
Scientific reports 2017 Aug 10;7(1):7774
Phosphocreatine protects endothelial cells from Methylglyoxal induced oxidative stress and apoptosis via the regulation of PI3K/Akt/eNOS and NF-κB pathway.
Chu P, Han G, Ahsan A, Sun Z, Liu S, Zhang Z, Sun B, Song Y, Lin Y, Peng J, Tang Z
Vascular pharmacology 2017 Apr;91:26-35
Vascular pharmacology 2017 Apr;91:26-35
Long non-coding RNA TUG1 promotes cell proliferation and metastasis by negatively regulating miR-300 in gallbladder carcinoma.
Ma F, Wang SH, Cai Q, Jin LY, Zhou D, Ding J, Quan ZW
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Apr;88:863-869
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Apr;88:863-869
The Circadian Gene Clock Regulates Bone Formation Via PDIA3.
Yuan G, Hua B, Yang Y, Xu L, Cai T, Sun N, Yan Z, Lu C, Qian R
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2017 Apr;32(4):861-871
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2017 Apr;32(4):861-871
Terrein performs antitumor functions on esophageal cancer cells by inhibiting cell proliferation and synergistic interaction with cisplatin.
Wu Y, Zhu Y, Li S, Zeng M, Chu J, Hu P, Li J, Guo Q, Lv XB, Huang G
Oncology letters 2017 Apr;13(4):2805-2810
Oncology letters 2017 Apr;13(4):2805-2810
miR-150 is downregulated in osteosarcoma and suppresses cell proliferation, migration and invasion by targeting ROCK1.
Li CH, Yu TB, Qiu HW, Zhao X, Zhou CL, Qi C
Oncology letters 2017 Apr;13(4):2191-2197
Oncology letters 2017 Apr;13(4):2191-2197
Boschniakia Rossica Polysaccharide Triggers Laryngeal Carcinoma Cell Apoptosis by Regulating Expression of Bcl-2, Caspase-3, and P53.
Yao C, Cao X, Fu Z, Tian J, Dong W, Xu J, An K, Zhai L, Yu J
Medical science monitor : international medical journal of experimental and clinical research 2017 Apr 29;23:2059-2064
Medical science monitor : international medical journal of experimental and clinical research 2017 Apr 29;23:2059-2064
Tumor-associated macrophages promote Ezrin phosphorylation-mediated epithelial-mesenchymal transition in lung adenocarcinoma through FUT4/LeY up-regulation.
Wang A, Lu C, Ning Z, Gao W, Xie Y, Zhang N, Liang J, Abbasi FS, Yan Q, Liu J
Oncotarget 2017 Apr 25;8(17):28247-28259
Oncotarget 2017 Apr 25;8(17):28247-28259
The acute exposure of tetrachloro-p-benzoquinone (a.k.a. chloranil) triggers inflammation and neurological dysfunction via Toll-like receptor 4 signaling: The protective role of melatonin preconditioning.
Fu J, Xia X, Liu Z, Wang Y, Wang Y, Shi Q, Song X, Song E, Song Y
Toxicology 2017 Apr 15;381:39-50
Toxicology 2017 Apr 15;381:39-50
1,2-Dichloroethane impairs glucose and lipid homeostasis in the livers of NIH Swiss mice.
Wang T, Xu D, Fan Q, Rong W, Zheng J, Gao C, Li G, Zeng N, Guo T, Zeng L, Wang F, Xiao C, Cai L, Tang S, Deng X, Yin X, Huang M, Lu F, Hu Q, Chen W, Huang Z, Wang Q
Toxicology 2017 Apr 1;380:38-49
Toxicology 2017 Apr 1;380:38-49
High-dose irradiation in combination with toll-like receptor 9 agonist CpG oligodeoxynucleotide 7909 downregulates PD-L1 expression via the NF-κB signaling pathway in non-small cell lung cancer cells.
Chen X, Zhang Q, Luo Y, Gao C, Zhuang X, Xu G, Qiao T
OncoTargets and therapy 2016;9:6511-6518
OncoTargets and therapy 2016;9:6511-6518
Radiation promotes epithelial-to-mesenchymal transition and invasion of pancreatic cancer cell by activating carcinoma-associated fibroblasts.
Li D, Qu C, Ning Z, Wang H, Zang K, Zhuang L, Chen L, Wang P, Meng Z
American journal of cancer research 2016;6(10):2192-2206
American journal of cancer research 2016;6(10):2192-2206
Targeting Dynamin 2 as a Novel Pathway to Inhibit Cardiomyocyte Apoptosis Following Oxidative Stress.
Gao D, Yang J, Wu Y, Wang Q, Wang Q, Lai EY, Zhu J
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;39(6):2121-2134
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;39(6):2121-2134
N-Methyl-D-aspartate Receptor Excessive Activation Inhibited Fetal Rat Lung Development In Vivo and In Vitro.
Liao Z, Zhou X, Luo Z, Huo H, Wang M, Yu X, Cao C, Ding Y, Xiong Z, Yue S
BioMed research international 2016;2016:5843981
BioMed research international 2016;2016:5843981
The Generation and Characterization of Recombinant Protein and Antibodies of Clostridium perfringens Beta2 Toxin.
Zeng J, Song F, Yang Y, Ma C, Deng G, Li Y, Wang Y, Liu X
Journal of immunology research 2016;2016:5708468
Journal of immunology research 2016;2016:5708468
Quantitative Proteomic Profiling the Molecular Signatures of Annexin A5 in Lung Squamous Carcinoma Cells.
Sun B, Bai Y, Zhang L, Gong L, Qi X, Li H, Wang F, Chi X, Jiang Y, Shao S
PloS one 2016;11(9):e0163622
PloS one 2016;11(9):e0163622
The long noncoding RNA MALAT1 regulates the lipopolysaccharide-induced inflammatory response through its interaction with NF-κB.
Zhao G, Su Z, Song D, Mao Y, Mao X
FEBS letters 2016 Sep;590(17):2884-95
FEBS letters 2016 Sep;590(17):2884-95
Lactobacillus rhamnosus induced epithelial cell apoptosis, ameliorates inflammation and prevents colon cancer development in an animal model.
Gamallat Y, Meyiah A, Kuugbee ED, Hago AM, Chiwala G, Awadasseid A, Bamba D, Zhang X, Shang X, Luo F, Xin Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 Oct;83:536-541
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 Oct;83:536-541
Hydrogen Sulfide and Carbon Monoxide Protect Gastric Mucosa Compromised by Mild Stress Against Alendronate Injury.
Magierowski M, Magierowska K, Szmyd J, Surmiak M, Sliwowski Z, Kwiecien S, Brzozowski T
Digestive diseases and sciences 2016 Nov;61(11):3176-3189
Digestive diseases and sciences 2016 Nov;61(11):3176-3189
Quantitative proteomics reveals molecular mechanism of gamabufotalin and its potential inhibition on Hsp90 in lung cancer.
Zhang L, Yu Z, Wang Y, Wang X, Zhang L, Wang C, Yue Q, Wang X, Deng S, Huo X, Tian X, Huang S, Zhang B, Ma X
Oncotarget 2016 Nov 22;7(47):76551-76564
Oncotarget 2016 Nov 22;7(47):76551-76564
Progranulin deficiency leads to severe inflammation, lung injury and cell death in a mouse model of endotoxic shock.
Yu Y, Xu X, Liu L, Mao S, Feng T, Lu Y, Cheng Y, Wang H, Zhao W, Tang W
Journal of cellular and molecular medicine 2016 Mar;20(3):506-17
Journal of cellular and molecular medicine 2016 Mar;20(3):506-17
The tumor suppressor PTEN has a critical role in antiviral innate immunity.
Li S, Zhu M, Pan R, Fang T, Cao YY, Chen S, Zhao X, Lei CQ, Guo L, Chen Y, Li CM, Jokitalo E, Yin Y, Shu HB, Guo D
Nature immunology 2016 Mar;17(3):241-9
Nature immunology 2016 Mar;17(3):241-9
AMPK-mediated up-regulation of mTORC2 and MCL-1 compromises the anti-cancer effects of aspirin.
Gao M, Kong Q, Hua H, Yin Y, Wang J, Luo T, Jiang Y
Oncotarget 2016 Mar 29;7(13):16349-61
Oncotarget 2016 Mar 29;7(13):16349-61
Potassium supplementation inhibits IL-17A production induced by salt loading in human T lymphocytes via p38/MAPK-SGK1 pathway.
Wen W, Wan Z, Ren K, Zhou D, Gao Q, Wu Y, Wang L, Yuan Z, Zhou J
Experimental and molecular pathology 2016 Jun;100(3):370-7
Experimental and molecular pathology 2016 Jun;100(3):370-7
Myricetin ameliorates brain injury and neurological deficits via Nrf2 activation after experimental stroke in middle-aged rats.
Wu S, Yue Y, Peng A, Zhang L, Xiang J, Cao X, Ding H, Yin S
Food & function 2016 Jun 15;7(6):2624-34
Food & function 2016 Jun 15;7(6):2624-34
Carboxy-terminal modulator protein attenuated extracellular matrix deposit by inhibiting phospho-Akt, TGF-β1 and α-SMA in kidneys of diabetic mice.
Chen N, Hao J, Li L, Li F, Liu S, Duan H
Biochemical and biophysical research communications 2016 Jun 10;474(4):753-760
Biochemical and biophysical research communications 2016 Jun 10;474(4):753-760
Lipodystrophy and severe metabolic dysfunction in mice with adipose tissue-specific insulin receptor ablation.
Qiang G, Whang Kong H, Xu S, Pham HA, Parlee SD, Burr AA, Gil V, Pang J, Hughes A, Gu X, Fantuzzi G, MacDougald OA, Liew CW
Molecular metabolism 2016 Jul;5(7):480-490
Molecular metabolism 2016 Jul;5(7):480-490
miR-223 enhances the sensitivity of non-small cell lung cancer cells to erlotinib by targeting the insulin-like growth factor-1 receptor.
Zhao FY, Han J, Chen XW, Wang J, Wang XD, Sun JG, Chen ZT
International journal of molecular medicine 2016 Jul;38(1):183-91
International journal of molecular medicine 2016 Jul;38(1):183-91
Development of a Biomimetic Chondroitin Sulfate-modified Hydrogel to Enhance the Metastasis of Tumor Cells.
Liu Y, Wang S, Sun D, Liu Y, Liu Y, Wang Y, Liu C, Wu H, Lv Y, Ren Y, Guo X, Sun G, Ma X
Scientific reports 2016 Jul 19;6:29858
Scientific reports 2016 Jul 19;6:29858
Novel Recombinant Protein FlaA N/C Protects against Radiation Injury via NF-κB Signaling.
Xu Y, Wu D, Fan Y, Li P, Du H, Shi J, Wang D, Zhou X
Radiation research 2016 Jan;185(1):77-86
Radiation research 2016 Jan;185(1):77-86
[Corrigendum] Cannabinoid WIN55, 212-2 induces cell cycle arrest and inhibits the proliferation and migration of human BEL7402 hepatocellular carcinoma cells.
Xu D, Wang J, Zhou Z, He Z, Zhao Q
Molecular medicine reports 2016 Jan;13(1):1054
Molecular medicine reports 2016 Jan;13(1):1054
Gamabufotalin, a major derivative of bufadienolide, inhibits VEGF-induced angiogenesis by suppressing VEGFR-2 signaling pathway.
Tang N, Shi L, Yu Z, Dong P, Wang C, Huo X, Zhang B, Huang S, Deng S, Liu K, Ma T, Wang X, Wu L, Ma XC
Oncotarget 2016 Jan 19;7(3):3533-47
Oncotarget 2016 Jan 19;7(3):3533-47
Bezafibrate-mizoribine interaction: Involvement of organic anion transporters OAT1 and OAT3 in rats.
Feng Y, Wang C, Liu Q, Meng Q, Huo X, Liu Z, Sun P, Yang X, Sun H, Qin J, Liu K
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2016 Jan 1;81:119-28
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2016 Jan 1;81:119-28
Nicotine Induced Murine Spermatozoa Apoptosis via Up-Regulation of Deubiquitinated RIP1 by Trim27 Promoter Hypomethylation.
Nie D, Zhang D, Dai J, Zhang M, Zhao X, Xu W, Chen Z, Wang L, Wang Z, Qiao Z
Biology of reproduction 2016 Feb;94(2):31
Biology of reproduction 2016 Feb;94(2):31
IL-17 intensifies IFN-γ-induced NOS2 upregulation in RAW 264.7 cells by further activating STAT1 and NF-κB.
Gao Q, Liu Y, Wu Y, Zhao Q, Wang L, Gao S, Wen W, Zhang W, Guo N, Zhou J, Yuan Z
International journal of molecular medicine 2016 Feb;37(2):347-58
International journal of molecular medicine 2016 Feb;37(2):347-58
Effect of acute lipopolysaccharide-induced inflammation in intracerebroventricular-streptozotocin injected rats.
Murtishaw AS, Heaney CF, Bolton MM, Sabbagh JJ, Langhardt MA, Kinney JW
Neuropharmacology 2016 Feb;101:110-22
Neuropharmacology 2016 Feb;101:110-22
ApoA-I induces S1P release from endothelial cells through ABCA1 and SR-BI in a positive feedback manner.
Liu X, Ren K, Suo R, Xiong SL, Zhang QH, Mo ZC, Tang ZL, Jiang Y, Peng XS, Yi GH
Journal of physiology and biochemistry 2016 Dec;72(4):657-667
Journal of physiology and biochemistry 2016 Dec;72(4):657-667
Establishment of a first-line second-line treatment model for human pulmonary adenocarcinoma.
Wang L, Wang Y, Guan Q, Liu Y, He T, Wang J
Oncology letters 2016 Dec;12(6):4461-4466
Oncology letters 2016 Dec;12(6):4461-4466
Interaction between endogenous carbon monoxide and hydrogen sulfide in the mechanism of gastroprotection against acute aspirin-induced gastric damage.
Magierowski M, Magierowska K, Hubalewska-Mazgaj M, Adamski J, Bakalarz D, Sliwowski Z, Pajdo R, Kwiecien S, Brzozowski T
Pharmacological research 2016 Dec;114:235-250
Pharmacological research 2016 Dec;114:235-250
Anti-tumor effects of osthole on ovarian cancer cells in vitro.
Jiang G, Liu J, Ren B, Tang Y, Owusu L, Li M, Zhang J, Liu L, Li W
Journal of ethnopharmacology 2016 Dec 4;193:368-376
Journal of ethnopharmacology 2016 Dec 4;193:368-376
Casitas B-cell lymphoma (Cbl) proteins protect mammary epithelial cells from proteotoxicity of active c-Src accumulation.
Mukhopadhyay C, Triplett A, Bargar T, Heckman C, Wagner KU, Naramura M
Proceedings of the National Academy of Sciences of the United States of America 2016 Dec 20;113(51):E8228-E8237
Proceedings of the National Academy of Sciences of the United States of America 2016 Dec 20;113(51):E8228-E8237
State estimation and prediction using clustered particle filters.
Lee Y, Majda AJ
Proceedings of the National Academy of Sciences of the United States of America 2016 Dec 20;113(51):14609-14614
Proceedings of the National Academy of Sciences of the United States of America 2016 Dec 20;113(51):14609-14614
Disrupting MALAT1/miR-200c sponge decreases invasion and migration in endometrioid endometrial carcinoma.
Li Q, Zhang C, Chen R, Xiong H, Qiu F, Liu S, Zhang M, Wang F, Wang Y, Zhou X, Xiao G, Wang X, Jiang Q
Cancer letters 2016 Dec 1;383(1):28-40
Cancer letters 2016 Dec 1;383(1):28-40
miR-1273g-3p modulates activation and apoptosis of hepatic stellate cells by directly targeting PTEN in HCV-related liver fibrosis.
Niu X, Fu N, Du J, Wang R, Wang Y, Zhao S, Du H, Wang B, Zhang Y, Sun D, Nan Y
FEBS letters 2016 Aug;590(16):2709-24
FEBS letters 2016 Aug;590(16):2709-24
MiR-770-5p inhibits cisplatin chemoresistance in human ovarian cancer by targeting ERCC2.
Zhao H, Yu X, Ding Y, Zhao J, Wang G, Wu X, Jiang J, Peng C, Guo GZ, Cui S
Oncotarget 2016 Aug 16;7(33):53254-53268
Oncotarget 2016 Aug 16;7(33):53254-53268
Calcium efflux from the endoplasmic reticulum regulates cisplatin-induced apoptosis in human cervical cancer HeLa cells.
Shen L, Wen N, Xia M, Zhang YU, Liu W, Xu YE, Sun L
Oncology letters 2016 Apr;11(4):2411-2419
Oncology letters 2016 Apr;11(4):2411-2419
Highly expressed UNC119 promotes hepatocellular carcinoma cell proliferation through Wnt/β-catenin signaling and predicts a poor prognosis.
Lei B, Chai W, Wang Z, Liu R
American journal of cancer research 2015;5(10):3123-34
American journal of cancer research 2015;5(10):3123-34
Study on the Dynamic Biological Characteristics of Sca-1(+) Hematopoietic Stem and Progenitor Cell Senescence.
Geng S, Mu XY, Chen XB, Hou JY, Jia DY, Xu CY, Wang YP
Stem cells international 2015;2015:954120
Stem cells international 2015;2015:954120
Liquiritigenin Protects Rats from Carbon Tetrachloride Induced Hepatic Injury through PGC-1α Pathway.
Zhang Y, He Y, Yu H, Ma F, Wu J, Zhang X
Evidence-based complementary and alternative medicine : eCAM 2015;2015:649568
Evidence-based complementary and alternative medicine : eCAM 2015;2015:649568
MYBL2 guides autophagy suppressor VDAC2 in the developing ovary to inhibit autophagy through a complex of VDAC2-BECN1-BCL2L1 in mammals.
Yuan J, Zhang Y, Sheng Y, Fu X, Cheng H, Zhou R
Autophagy 2015;11(7):1081-98
Autophagy 2015;11(7):1081-98
Panaxadiol Saponin and Dexamethasone Improve Renal Function in Lipopolysaccharide-Induced Mouse Model of Acute Kidney Injury.
Chen Y, Du Y, Li Y, Wang X, Gao P, Yang G, Fang Y, Meng Y, Zhao X
PloS one 2015;10(7):e0134653
PloS one 2015;10(7):e0134653
The Nucleocapsid Protein of Coronaviruses Acts as a Viral Suppressor of RNA Silencing in Mammalian Cells.
Cui L, Wang H, Ji Y, Yang J, Xu S, Huang X, Wang Z, Qin L, Tien P, Zhou X, Guo D, Chen Y
Journal of virology 2015 Sep;89(17):9029-43
Journal of virology 2015 Sep;89(17):9029-43
FUS Interacts with HSP60 to Promote Mitochondrial Damage.
Deng J, Yang M, Chen Y, Chen X, Liu J, Sun S, Cheng H, Li Y, Bigio EH, Mesulam M, Xu Q, Du S, Fushimi K, Zhu L, Wu JY
PLoS genetics 2015 Sep;11(9):e1005357
PLoS genetics 2015 Sep;11(9):e1005357
Exposure to airborne PM2.5 suppresses microRNA expression and deregulates target oncogenes that cause neoplastic transformation in NIH3T3 cells.
Liu C, Guo H, Cheng X, Shao M, Wu C, Wang S, Li H, Wei L, Gao Y, Tan W, Cheng S, Wu T, Yu D, Lin D
Oncotarget 2015 Oct 6;6(30):29428-39
Oncotarget 2015 Oct 6;6(30):29428-39
HBx-related long non-coding RNA DBH-AS1 promotes cell proliferation and survival by activating MAPK signaling in hepatocellular carcinoma.
Huang JL, Ren TY, Cao SW, Zheng SH, Hu XM, Hu YW, Lin L, Chen J, Zheng L, Wang Q
Oncotarget 2015 Oct 20;6(32):33791-804
Oncotarget 2015 Oct 20;6(32):33791-804
Olaquindox induces DNA damage via the lysosomal and mitochondrial pathway involving ROS production and p53 activation in HEK293 cells.
Yang Y, Jiang L, She Y, Chen M, Li Q, Yang G, Geng C, Tang L, Zhong L, Jiang L, Liu X
Environmental toxicology and pharmacology 2015 Nov;40(3):792-9
Environmental toxicology and pharmacology 2015 Nov;40(3):792-9
Inhibition of migration and induction of apoptosis in LoVo human colon cancer cells by polysaccharides from Ganoderma lucidum.
Liang ZE, Yi YJ, Guo YT, Wang RC, Hu QL, Xiong XY
Molecular medicine reports 2015 Nov;12(5):7629-36
Molecular medicine reports 2015 Nov;12(5):7629-36
Establishment and Characterization of Human Germline Stem Cell Line with Unlimited Proliferation Potentials and no Tumor Formation.
Hou J, Niu M, Liu L, Zhu Z, Wang X, Sun M, Yuan Q, Yang S, Zeng W, Liu Y, Li Z, He Z
Scientific reports 2015 Nov 20;5:16922
Scientific reports 2015 Nov 20;5:16922
A Critical Role for Cysteine 57 in the Biological Functions of Selenium Binding Protein-1.
Ying Q, Ansong E, Diamond AM, Yang W
International journal of molecular sciences 2015 Nov 18;16(11):27599-608
International journal of molecular sciences 2015 Nov 18;16(11):27599-608
MicroRNA-206 attenuates tumor proliferation and migration involving the downregulation of NOTCH3 in colorectal cancer.
Wang XW, Xi XQ, Wu J, Wan YY, Hui HX, Cao XF
Oncology reports 2015 Mar;33(3):1402-10
Oncology reports 2015 Mar;33(3):1402-10
Reactive stroma component COL6A1 is upregulated in castration-resistant prostate cancer and promotes tumor growth.
Zhu YP, Wan FN, Shen YJ, Wang HK, Zhang GM, Ye DW
Oncotarget 2015 Jun 10;6(16):14488-96
Oncotarget 2015 Jun 10;6(16):14488-96
Tetrachlorobenzoquinone triggers the cleavage of Bid and promotes the cross-talk of extrinsic and intrinsic apoptotic signalings in pheochromocytoma (PC) 12 cells.
Hu L, Su C, Song X, Shi Q, Fu J, Xia X, Xu D, Song E, Song Y
Neurotoxicology 2015 Jul;49:149-57
Neurotoxicology 2015 Jul;49:149-57
Trophoblast glycoprotein promotes pancreatic ductal adenocarcinoma cell metastasis through Wnt/planar cell polarity signaling.
He P, Jiang S, Ma M, Wang Y, Li R, Fang F, Tian G, Zhang Z
Molecular medicine reports 2015 Jul;12(1):503-9
Molecular medicine reports 2015 Jul;12(1):503-9
The safety and anti-hypercholesterolemic effect of coptisine in Syrian golden hamsters.
He K, Ye X, Wu H, Wang Y, Zou Z, Ning N, Hu Y, Chen B, Fang X, Li X
Lipids 2015 Feb;50(2):185-94
Lipids 2015 Feb;50(2):185-94
SPAG6 silencing inhibits the growth of the malignant myeloid cell lines SKM-1 and K562 via activating p53 and caspase activation-dependent apoptosis.
Yang B, Wang L, Luo X, Chen L, Yang Z, Liu L
International journal of oncology 2015 Feb;46(2):649-56
International journal of oncology 2015 Feb;46(2):649-56
Artificial sweetener neohesperidin dihydrochalcone showed antioxidative, anti-inflammatory and anti-apoptosis effects against paraquat-induced liver injury in mice.
Shi Q, Song X, Fu J, Su C, Xia X, Song E, Song Y
International immunopharmacology 2015 Dec;29(2):722-729
International immunopharmacology 2015 Dec;29(2):722-729
Dynamic expression of miR-206-3p during mouse skin development is independent of keratinocyte differentiation.
Mu Y, Zhou H, Wu WJ, Hu LC, Chen HB
Molecular medicine reports 2015 Dec;12(6):8113-20
Molecular medicine reports 2015 Dec;12(6):8113-20
Cannabinoid WIN55, 212-2 induces cell cycle arrest and inhibits the proliferation and migration of human BEL7402 hepatocellular carcinoma cells.
Xu D, Wang J, Zhou Z, He Z, Zhao Q
Molecular medicine reports 2015 Dec;12(6):7963-70
Molecular medicine reports 2015 Dec;12(6):7963-70
miR-140-5p regulates adipocyte differentiation by targeting transforming growth factor-β signaling.
Zhang X, Chang A, Li Y, Gao Y, Wang H, Ma Z, Li X, Wang B
Scientific reports 2015 Dec 11;5:18118
Scientific reports 2015 Dec 11;5:18118
Postnatal alterations in GABAB receptor tone produce sensorimotor gating deficits and protein level differences in adulthood.
Bolton MM, Heaney CF, Murtishaw AS, Sabbagh JJ, Magcalas CM, Kinney JW
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 2015 Apr;41:17-27
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 2015 Apr;41:17-27
RAD51B Activity and Cell Cycle Regulation in Response to DNA Damage in Breast Cancer Cell Lines.
Lee PS, Fang J, Jessop L, Myers T, Raj P, Hu N, Wang C, Taylor PR, Wang J, Khan J, Jasin M, Chanock SJ
Breast cancer : basic and clinical research 2014;8:135-44
Breast cancer : basic and clinical research 2014;8:135-44
Inhibition of 15-lipoxygenase (15-LOX) reverses hypoxia-induced down-regulation of potassium channels Kv1.5 and Kv2.1Inhibition of 15-lipoxygenase (15-LOX) reverses hypoxia-induced down-regulation of potassium channels Kv1.5 and Kv2.1.
Liu W, Wang D, Song K, Chen L, Zhu Y, Liu P, Zhu Y
International journal of clinical and experimental medicine 2014;7(11):4147-53
International journal of clinical and experimental medicine 2014;7(11):4147-53
Role of α-lipoic acid in LPS/d-GalN induced fulminant hepatic failure in mice: studies on oxidative stress, inflammation and apoptosis.
Xia X, Su C, Fu J, Zhang P, Jiang X, Xu D, Hu L, Song E, Song Y
International immunopharmacology 2014 Oct;22(2):293-302
International immunopharmacology 2014 Oct;22(2):293-302
Identification and validation of a novel microRNA-like molecule derived from a cytoplasmic RNA virus antigenome by bioinformatics and experimental approaches.
Shi J, Duan Z, Sun J, Wu M, Wang B, Zhang J, Wang H, Hu N, Hu Y
Virology journal 2014 Jul 1;11:121
Virology journal 2014 Jul 1;11:121
Edwardsiella tarda-Induced cytotoxicity depends on its type III secretion system and flagellin.
Xie HX, Lu JF, Rolhion N, Holden DW, Nie P, Zhou Y, Yu XJ
Infection and immunity 2014 Aug;82(8):3436-45
Infection and immunity 2014 Aug;82(8):3436-45
Integrative genomics in combination with RNA interference identifies prognostic and functionally relevant gene targets for oral squamous cell carcinoma.
Xu C, Wang P, Liu Y, Zhang Y, Fan W, Upton MP, Lohavanichbutr P, Houck JR, Doody DR, Futran ND, Zhao LP, Schwartz SM, Chen C, Méndez E
PLoS genetics 2013;9(1):e1003169
PLoS genetics 2013;9(1):e1003169
Calpain mediates caspase-dependent apoptosis initiated by hydrogen peroxide in pancreatic acinar AR42J cells.
Weber H, Müller L, Jonas L, Schult C, Sparmann G, Schuff-Werner P
Free radical research 2013 May;47(5):432-46
Free radical research 2013 May;47(5):432-46
The hepatitis B virus X protein downregulates NF-κB signaling pathways through decreasing the Notch signaling pathway in HBx-transformed L02 cells.
Luo J, Zhou H, Wang F, Xia X, Sun Q, Wang R, Cheng B
International journal of oncology 2013 May;42(5):1636-43
International journal of oncology 2013 May;42(5):1636-43
Limb-girdle muscular dystrophy 1F is caused by a microdeletion in the transportin 3 gene.
Melià MJ, Kubota A, Ortolano S, Vílchez JJ, Gámez J, Tanji K, Bonilla E, Palenzuela L, Fernández-Cadenas I, Pristoupilová A, García-Arumí E, Andreu AL, Navarro C, Hirano M, Martí R
Brain : a journal of neurology 2013 May;136(Pt 5):1508-17
Brain : a journal of neurology 2013 May;136(Pt 5):1508-17
Cytohesin-2 as a novel prognostic marker for hepatocellular carcinoma.
Xu K, Gao J, Yang X, Yao Y, Liu Q
Oncology reports 2013 Jun;29(6):2211-8
Oncology reports 2013 Jun;29(6):2211-8
Roles of 3,4-methylenedioxymethamphetamine (MDMA)-induced alteration of connexin43 and intracellular Ca(2+) oscillation in its cardiotoxicity.
Zhuo L, Liu Q, Liu L, Sun TY, Wang RS, Qu GQ, Liu Q, Liu Y, Ren L
Toxicology 2013 Aug 9;310:61-72
Toxicology 2013 Aug 9;310:61-72
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The beta actin antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human beta actin. This antibody recognizes human,mouse,rat,zebrafish, monkey antigen. The beta actin antibody has been validated for the following applications: ELISA, IF, WB, IHC analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using ACTB antibody 20536-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human colon using 20536-1-AP(ACTB antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human colon using 20536-1-AP(ACTB antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue
