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- Antibody Data
- Antigen structure
- References [2459]
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- Western blot [1]
- Immunocytochemistry [1]
- Immunoprecipitation [1]
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- Product number
- 66009-1-Ig - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#66009-1-Ig, RRID:AB_2687938
- Product name
- beta actin antibody
- Antibody type
- Monoclonal
- Description
- KD/KO validated Beta Actin antibody (Cat. #66009-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, mouse, rat, hamster, zebrafish, monkey, dog and has been validated for the following applications: FC, IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat, Canine, Hamster, Simian, Zebrafish
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 2D4H5
- Vial size
- 150ul
Submitted references M1-type microglia can induce astrocytes to deposit chondroitin sulfate proteoglycan after spinal cord injury.
Injectable self-healing hydrogel with siRNA delivery property for sustained STING silencing and enhanced therapy of intervertebral disc degeneration.
Systematic characterization of the metabolites of defatted walnut powder extract in vivo and screening of the mechanisms against NAFLD by UPLC-Q-Exactive Orbitrap MS combined with network pharmacology.
Moringa oleifera Lam. seed extract protects kidney function in rats with diabetic nephropathy by increasing GSK-3β activity and activating the Nrf2/HO-1 pathway.
Ror2 mediates chronic post-thoracotomy pain by inducing the transformation of A1/A2 reactive astrocytes in rats.
Resveratrol Improves Synaptic Plasticity in Hypoxic-Ischemic Brain Injury in Neonatal Mice via Alleviating SIRT1/NF-κB Signaling-Mediated Neuroinflammation.
Inflammatory cell-derived CXCL3 promotes pancreatic cancer metastasis through a novel myofibroblast-hijacked cancer escape mechanism.
A calcium phosphate drug carrier loading with 5-fluorouracil achieving a synergistic effect for pancreatic cancer therapy.
SIRT1 induces the accumulation of TAMs at colorectal cancer tumor sites via the CXCR4/CXCL12 axis.
Inhibition of progesterone receptor membrane component-1 exacerbates neonatal hypoxic-ischemic cerebral damage in male mice.
Electroacupuncture alleviates spatial memory deficits in METH withdrawal mice by enhancing astrocyte-mediated glutamate clearance in the dCA1.
Zinc-finger protein 750 mitigates malignant biological behavior of oral CSC-like cells enriched from parental CAL-27 cells.
DNMT3B regulates proliferation of A549 cells through the microRNA-152-3p/NCAM1 pathway.
Morphological changes of macrophages and their potential contribution to tendon healing.
METTL3 Regulates Liver Homeostasis, Hepatocyte Ploidy, and Circadian Rhythm-Controlled Gene Expression in Mice.
Pyridoxamine ameliorates methylglyoxal-induced macrophage dysfunction to facilitate tissue repair in diabetic wounds.
RNF2 promotes the progression of colon cancer by regulating ubiquitination and degradation of IRF4.
Silencing TXNIP ameliorates high uric acid-induced insulin resistance via the IRS2/AKT and Nrf2/HO-1 pathways in macrophages.
Mettl3 inhibits the apoptosis and autophagy of chondrocytes in inflammation through mediating Bcl2 stability via Ythdf1-mediated m6A modification.
Overexpression of DOCK6 in oral squamous cell cancer promotes cellular migration and invasion and is associated with poor prognosis.
Cotargeting of Bcl-2 and Mcl-1 shows promising antileukemic activity against AML cells including those with acquired cytarabine resistance.
ERK/p38/ROS burst responses to environmentally relevant concentrations of diphenyl phosphate-evoked neutrophil extracellular traps formation: Assessing the role of autophagy.
Novel 5-fluorouracil sensitizers for colorectal cancer therapy: Design and synthesis of S1P receptor 2 (S1PR2) antagonists.
Saponins from Nigella glandulifera seeds attenuate collagen-induced rheumatoid arthritis in rats via the OPG/RANKL/NF-κB and Ang/Tie-2 pathways.
Guizhi-Shaoyao-Zhimu decoction attenuates monosodium urate crystal-induced inflammation through inactivation of NF-κB and NLRP3 inflammasome.
The ethanol extract of flower buds of Tussilago farfara L. attenuates cigarette smoke-induced lung inflammation through regulating NLRP3 inflammasome, Nrf2, and NF-κB.
Sodium hydrosulfide reverses β2-microglobulin-induced depressive-like behaviors of male Sprague-Dawley rats: Involving improvement of synaptic plasticity and enhancement of Warburg effect in hippocampus.
Salubrinal protects against inflammatory response in macrophage and attenuates psoriasiform skin inflammation by antagonizing NF-κB signaling pathway.
Pyk2 suppresses contextual fear memory in an autophosphorylation-independent manner.
The amino acids of Autographa californica multiple nucleopolyhedrovirus P48 critical for the association with Ac93 are important for the nuclear egress of nucleocapsids and efficient formation of intranuclear microvesicles.
Ellagic acid ameliorates paraquat-induced liver injury associated with improved gut microbial profile.
The PERK/PKR-eIF2α Pathway Negatively Regulates Porcine Hemagglutinating Encephalomyelitis Virus Replication by Attenuating Global Protein Translation and Facilitating Stress Granule Formation.
Anti-tumor effect of Yanggan Huayu granule by inducing AKT-mediated apoptosis in hepatocellular carcinoma.
Tanshinone IIA alleviates NLRP3 inflammasome-mediated pyroptosis in Mycobacterium tuberculosis-(H37Ra-) infected macrophages by inhibiting endoplasmic reticulum stress.
Overexpression of Lin28a induces a primary ovarian insufficiency phenotype via facilitation of primordial follicle activation in mice.
PTP70-2, a novel polysaccharide from Polygala tenuifolia, prevents neuroinflammation and protects neurons by suppressing the TLR4-mediated MyD88/NF-κB signaling pathway.
Neuroglobin expression and function in the temporal cortex of bilirubin encephalopathy rats.
Role of TGF-β1 in Fluoride-Treated Osteoblasts at Different Stages.
Zinc Protects against Heat Stress-Induced Apoptosis via the Inhibition of Endoplasmic Reticulum Stress in TM3 Leydig Cells.
miRNA-338-3p inhibits glioma cell proliferation and progression by targeting MYT1L.
Vibrio harveyi infections induce production of proinflammatory cytokines in murine peritoneal macrophages via activation of p38 MAPK and NF-κB pathways, but reversed by PI3K/AKT pathways.
Anti-proliferation and anti-inflammation effects of corilagin in rheumatoid arthritis by downregulating NF-κB and MAPK signaling pathways.
Physiological and transcriptomic analyses reveal the toxicological mechanism and risk assessment of environmentally-relevant waterborne tetracycline exposure on the gills of tilapia (Oreochromis niloticus).
Aspirin relieves the calcification of aortic smooth muscle cells by enhancing the heat shock response.
Inhibiting Hyper-O-GlcNAcylation of c-Myc accelerate diabetic wound healing by alleviating keratinocyte dysfunction.
Comprehensive analysis of abnormal expression, prognostic value and oncogenic role of the hub gene FN1 in pancreatic ductal adenocarcinoma via bioinformatic analysis and in vitro experiments.
Identification of KIF4A as a pan-cancer diagnostic and prognostic biomarker via bioinformatics analysis and validation in osteosarcoma cell lines.
PPy@Fe3O4 Nanoparticles Inhibit Tumor Growth and Metastasis Through Chemodynamic and Photothermal Therapy in Non-small Cell Lung Cancer.
Cadherin-12 Regulates Neurite Outgrowth Through the PKA/Rac1/Cdc42 Pathway in Cortical Neurons.
LncRNA FEZF1-AS1 Promotes Multi-Drug Resistance of Gastric Cancer Cells via Upregulating ATG5.
Eicosapentaenoic Acid-Induced Autophagy Attenuates Intervertebral Disc Degeneration by Suppressing Endoplasmic Reticulum Stress, Extracellular Matrix Degradation, and Apoptosis.
Autophagy Regulates VDAC3 Ubiquitination by FBXW7 to Promote Erastin-Induced Ferroptosis in Acute Lymphoblastic Leukemia.
TMT-Based Proteomic Explores the Influence of DHEA on the Osteogenic Differentiation of hBMSCs.
ESRRB Facilitates the Conversion of Trophoblast-Like Stem Cells From Induced Pluripotent Stem Cells by Directly Regulating CDX2.
Cyclophosphamide Exposure Causes Long-Term Detrimental Effect of Oocytes Developmental Competence Through Affecting the Epigenetic Modification and Maternal Factors' Transcription During Oocyte Growth.
The E3 Ligase PIAS1 Regulates p53 Sumoylation to Control Stress-Induced Apoptosis of Lens Epithelial Cells Through the Proapoptotic Regulator Bax.
SARS-CoV-2 Host Receptor ACE2 Protein Expression Atlas in Human Gastrointestinal Tract.
MYC Enhances Cholesterol Biosynthesis and Supports Cell Proliferation Through SQLE.
NTNG1 Modulates Cisplatin Resistance in Epithelial Ovarian Cancer Cells via the GAS6/AXL/Akt Pathway.
TAp63α Is Involved in Tobacco Smoke-Induced Lung Cancer EMT and the Anti-cancer Activity of Curcumin via miR-19 Transcriptional Suppression.
Grb2 Induces Cardiorenal Syndrome Type 3: Roles of IL-6, Cardiomyocyte Bioenergetics, and Akt/mTOR Pathway.
Zirconia Nanoparticles Induce HeLa Cell Death Through Mitochondrial Apoptosis and Autophagy Pathways Mediated by ROS.
Maslinic Acid Attenuates Ischemia/Reperfusion Injury-Induced Myocardial Inflammation and Apoptosis by Regulating HMGB1-TLR4 Axis.
Loss of Hepatic Surf4 Depletes Lipid Droplets in the Adrenal Cortex but Does Not Impair Adrenal Hormone Production.
S-Propargyl-Cysteine Attenuates Diabetic Cardiomyopathy in db/db Mice Through Activation of Cardiac Insulin Receptor Signaling.
The Regulation of Staphylococcus aureus-Induced Inflammatory Responses in Bovine Mammary Epithelial Cells.
β-Sitosterol Ameliorates Endometrium Receptivity in PCOS-Like Mice: The Mediation of Gut Microbiota.
Exosomal MicroRNA-181a Derived From Mesenchymal Stem Cells Improves Gut Microbiota Composition, Barrier Function, and Inflammatory Status in an Experimental Colitis Model.
Liraglutide Protects Nucleus Pulposus Cells Against High-Glucose Induced Apoptosis by Activating PI3K/Akt/ mTOR/Caspase-3 and PI3K/Akt/GSK3β/Caspase-3 Signaling Pathways.
Hydroxysafflor yellow A acutely attenuates blood-brain barrier permeability, oxidative stress, inflammation and apoptosis in traumatic brain injury in rats1.
Autophagy Prevents Osteocyte Cell Death under Hypoxic Conditions.
Long Noncoding RNA HCG9 Promotes Osteosarcoma Progression through RAD51 by Acting as a ceRNA of miR-34b-3p.
Exosomes Containing LINC00636 Inhibit MAPK1 through the miR-450a-2-3p Overexpression in Human Pericardial Fluid and Improve Cardiac Fibrosis in Patients with Atrial Fibrillation.
TRIM29 Reverses Oxaliplatin Resistance of P53 Mutant Colon Cancer Cell.
Constitutive Androstane Receptor-Mediated Inhibition of Metformin on Phase II Metabolic Enzyme SULT2A1.
Ze-Qi-Tang Formula Induces Granulocytic Myeloid-Derived Suppressor Cell Apoptosis via STAT3/S100A9/Bcl-2/Caspase-3 Signaling to Prolong the Survival of Mice with Orthotopic Lung Cancer.
ADAM17 Mediates Hypoxia-Induced Keratinocyte Migration via the p38/MAPK Pathway.
Catalpol-Induced AMPK Activation Alleviates Cisplatin-Induced Nephrotoxicity through the Mitochondrial-Dependent Pathway without Compromising Its Anticancer Properties.
High Methionine Diet-Induced Alzheimer's Disease like Symptoms Are Accompanied by 5-Methylcytosine Elevated Levels in the Brain.
Neferine Protects against Hypoxic-Ischemic Brain Damage in Neonatal Rats by Suppressing NLRP3-Mediated Inflammasome Activation.
The Regulation of ROS- and BECN1-Mediated Autophagy by Human Telomerase Reverse Transcriptase in Glioblastoma.
Overexpression of RIPK4 Predicts Poor Prognosis and Promotes Metastasis in Ovarian Cancer.
Uncovering the Pharmacology of Xiaochaihu Decoction in the Treatment of Acute Pancreatitis Based on the Network Pharmacology.
Taohong Siwu-Containing Serum Enhances Angiogenesis in Rat Aortic Endothelial Cells by Regulating the VHL/HIF-1α/VEGF Signaling Pathway.
GDF-15 Suppresses Atherosclerosis by Inhibiting oxLDL-Induced Lipid Accumulation and Inflammation in Macrophages.
Deficiency of MIF Accentuates Overloaded Compression-Induced Nucleus Pulposus Cell Oxidative Damage via Depressing Mitophagy.
Epigallocatechin-3-Gallate Alleviates High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease via Inhibition of Apoptosis and Promotion of Autophagy through the ROS/MAPK Signaling Pathway.
EZH2 Mediates miR-146a-5p/HIF-1α to Alleviate Inflammation and Glycolysis after Acute Spinal Cord Injury.
A Network Pharmacology Approach for Exploring the Mechanisms of Panax notoginseng Saponins in Ischaemic Stroke.
Inhibition of α-Synuclein Accumulation Improves Neuronal Apoptosis and Delayed Postoperative Cognitive Recovery in Aged Mice.
POU2F1 Promotes Cell Viability and Tumor Growth in Gastric Cancer through Transcriptional Activation of lncRNA TTC3-AS1.
Baihe Jizihuang Tang Ameliorates Chronic Unpredictable Mild Stress-Induced Depression-Like Behavior: Integrating Network Pharmacology and Brain-Gut Axis Evaluation.
NOX4-Derived ROS Mediates TGF-β1-Induced Metabolic Reprogramming during Epithelial-Mesenchymal Transition through the PI3K/AKT/HIF-1α Pathway in Glioblastoma.
Study on the Antitumor Effect and Glycolysis of Andrographolide in Anaplastic Thyroid Carcinoma.
Berbamine Inhibits Cell Proliferation and Migration and Induces Cell Death of Lung Cancer Cells via Regulating c-Maf, PI3K/Akt, and MDM2-P53 Pathways.
The Key Ingredient Acacetin in Weishu Decoction Alleviates Gastrointestinal Motility Disorder Based on Network Pharmacology Analysis.
The Effect of miR-520b on Macrophage Polarization and T Cell Immunity by Targeting PTEN in Breast Cancer.
OM-MSCs Alleviate the Golgi Apparatus Stress Response following Cerebral Ischemia/Reperfusion Injury via the PEDF-PI3K/Akt/mTOR Signaling Pathway.
The Dietary Supplement γ-Oryzanol Attenuates Hepatic Ischemia Reperfusion Injury via Inhibiting Endoplasmic Reticulum Stress and HMGB1/NLRP3 Inflammasome.
Ameliorative Effects and Mechanism of Buyang Huanwu Decoction on Pulmonary Vascular Remodeling: Network and Experimental Analyses.
Comparative Efficacy of Haizao Yuhu Decoction Composed of Different Varieties of Glycyrrhiza in Goiter Rats.
Zinc Regulates Glucose Metabolism of the Spinal Cord and Neurons and Promotes Functional Recovery after Spinal Cord Injury through the AMPK Signaling Pathway.
Nrf2 Pathway Ameliorates Bladder Dysfunction in Cyclophosphamide-Induced Cystitis via Suppression of Oxidative Stress.
Chlorogenic Acid Alleviates Colon Mucosal Damage Induced by a High-Fat Diet via Gut Microflora Adjustment to Increase Short-Chain Fatty Acid Accumulation in Rats.
Electroacupuncture Ameliorates Depression-Like Behaviour in Rats by Enhancing Synaptic Plasticity via the GluN2B/CaMKII/CREB Signalling Pathway.
Inhibition of the PERK/TXNIP/NLRP3 Axis by Baicalin Reduces NLRP3 Inflammasome-Mediated Pyroptosis in Macrophages Infected with Mycobacterium tuberculosis.
Microglia-Derived Exosomes Improve Spinal Cord Functional Recovery after Injury via Inhibiting Oxidative Stress and Promoting the Survival and Function of Endothelia Cells.
Inhibiting PP2Acα Promotes the Malignant Phenotype of Gastric Cancer Cells through the ATM/METTL3 Axis.
Qingda granule exerts neuroprotective effects against ischemia/reperfusion-induced cerebral injury via lncRNA GAS5/miR-137 signaling pathway.
NSE, positively regulated by LINC00657-miR-93-5p axis, promotes small cell lung cancer (SCLC) invasion and epithelial-mesenchymal transition (EMT) process.
Simultaneous silencing Aurora-A and UHRF1 inhibits colorectal cancer cell growth through regulating expression of DNMT1 and STAT1.
GABAB receptor inhibits tumor progression and epithelial-mesenchymal transition via the regulation of Hippo/YAP1 pathway in colorectal cancer.
Macrophage migration inhibitory factor regulates joint capsule fibrosis by promoting TGF-β1 production in fibroblasts.
Aurka deficiency in the intestinal epithelium promotes age-induced obesity via propionate-mediated AKT activation.
Targeting HLA-F suppresses the proliferation of glioma cells via a reduction in hexokinase 2-dependent glycolysis.
FOXM1-induced miR-552 expression contributes to pancreatic cancer progression by targeting multiple tumor suppressor genes.
AKR1B10 confers resistance to radiotherapy via FFA/TLR4/NF-κB axis in nasopharyngeal carcinoma.
SOCS2 Suppresses Inflammation and Apoptosis during NASH Progression through Limiting NF-κB Activation in Macrophages.
KMT5A downregulation participated in High Glucose-mediated EndMT via Upregulation of ENO1 Expression in Diabetic Nephropathy.
The imbalance of PGD2-DPs pathway is involved in the type 2 diabetes brain injury by regulating autophagy.
Discovery of a novel HDACi structure that inhibits the proliferation of ovarian cancer cells in vivo and in vitro.
Deubiquitinase PSMD7 promotes the proliferation, invasion, and cisplatin resistance of gastric cancer cells by stabilizing RAD23B.
NCTD Prevents Renal Interstitial Fibrosis via Targeting Sp1/lncRNA Gm26669 Axis.
H2O2 gel bleaching induces cytotoxicity and pain conduction in dental pulp stem cells via intracellular reactive oxygen species on enamel/dentin disc.
Chirality and asymmetry increase the potency of candidate ADRM1/RPN13 inhibitors.
Harmine inhibits breast cancer cell migration and invasion by inducing the degradation of Twist1.
Systematic identification of autophagy-related proteins in Aedes albopictus.
Accurately Controlled Delivery of Temozolomide by Biocompatible UiO-66-NH2 Through Ultrasound to Enhance the Antitumor Efficacy and Attenuate the Toxicity for Treatment of Malignant Glioma.
Photobiomodulation Promotes Repair Following Spinal Cord Injury by Regulating the Transformation of A1/A2 Reactive Astrocytes.
5-HT7 Receptor Is Involved in Electroacupuncture Inhibition of Chronic Pain in the Spinal Cord.
IL-17 Inhibits Oligodendrocyte Progenitor Cell Proliferation and Differentiation by Increasing K+ Channel Kv1.3.
Injection of Anti-proBDNF Attenuates Hippocampal-Dependent Learning and Memory Dysfunction in Mice With Sepsis-Associated Encephalopathy.
Tetramethylpyrazine Alleviates Behavioral and Psychological Symptoms of Dementia Through Facilitating Hippocampal Synaptic Plasticity in Rats With Chronic Cerebral Hypoperfusion.
Dl-3-n-Butylphthalide Reduces Cognitive Deficits and Alleviates Neuropathology in P301S Tau Transgenic Mice.
IRE1α-XBP1 Affects the Mitochondrial Function of Aβ25-35-Treated SH-SY5Y Cells by Regulating Mitochondria-Associated Endoplasmic Reticulum Membranes.
Doxazosin Attenuates Liver Fibrosis by Inhibiting Autophagy in Hepatic Stellate Cells via Activation of the PI3K/Akt/mTOR Signaling Pathway.
Baicalin Alleviates Oxidative Stress and Inflammation in Diabetic Nephropathy via Nrf2 and MAPK Signaling Pathway.
Selective Inhibition of 11β-Hydroxysteroid Dehydrogenase Type 1 Attenuates High-Fat Diet-Induced Hepatic Steatosis in Mice.
ADAM17 and NF-κB p65 form a positive feedback loop that facilitates human esophageal squamous cell carcinoma cell viability.
Gαi1 Promoted Proliferation, Migration and Invasion via Activating the Akt-mTOR/Erk-MAPK Signaling Pathway in Renal Cell Carcinoma.
Regulation of IFN-Is by MEF2D Promotes Inflammatory Homeostasis in Microglia.
GADD45B Facilitates Metastasis of Ovarian Cancer Through Epithelial-Mesenchymal Transition.
Upregulation of Neuronal Cylindromatosis Expression is Essential for Electroacupuncture-Mediated Alleviation of Neuroinflammatory Injury by Regulating Microglial Polarization in Rats Subjected to Focal Cerebral Ischemia/Reperfusion.
Orexin-A Attenuates Inflammatory Responses in Lipopolysaccharide-Induced Neural Stem Cells by Regulating NF-KB and Phosphorylation of MAPK/P38/Erk Pathways.
MiRNA-223-3p Affects Mantle Cell Lymphoma Development by Regulating the CHUK/NF-ƘB2 Signaling Pathway.
The Significance of HOXC11 and LSH in Survival Prediction in Gastric Adenocarcinoma.
Network pharmacology-guided mechanism study uncovers inhibitory effect of Mahuang Decoction on lung cancer growth by impeding Akt/ERK signaling pathways.
Sevoflurane prevents pulmonary vascular remodeling and right ventricular dysfunction in pulmonary arterial hypertension in rats.
Dura cells in the etiopathogenesis of Crouzon syndrome: the effects of FGFR2 mutations in the dura cells on the proliferation of osteoblasts through the hippo/YAP mediated transcriptional regulation pathway.
Schisandrin C attenuates renal damage in diabetic nephropathy by regulating macrophage polarization.
Overexpression of the lncRNA AC012213.3 Promotes Proliferation, Migration and Invasion of Breast Cancer via RAD54B/PI3K/AKT Axis and is Associated with Worse Patient Prognosis.
LncRNA TMEM220-AS1 suppresses hepatocellular carcinoma cell proliferation and invasion by regulating the TMEM220/β-catenin axis.
LncRNA MALAT1 was regulated by HPV16 E7 independently of pRB in cervical cancer cells.
Inositol hexaphosphate sensitizes hepatocellular carcinoma to oxaliplatin relating inhibition of CCN2-LRP6-β-catenin-ABCG1 signaling pathway.
Caspase-11-Mediated Hepatocytic Pyroptosis Promotes the Progression of Nonalcoholic Steatohepatitis.
SLC39A7 promotes malignant behaviors in glioma via the TNF-α-mediated NF-κB signaling pathway.
Demethylzelasteral inhibits proliferation and EMT via repressing Wnt/β-catenin signaling in esophageal squamous cell carcinoma.
CDK5 Knockdown inhibits proliferation and induces apoptosis and Cell Cycle Arrest in Human Glioblastoma.
Punicalin Attenuates Breast Cancer-Associated Osteolysis by Inhibiting the NF-κB Signaling Pathway of Osteoclasts.
CircEpc1 Promotes Ricin Toxin-Induced Inflammation via Activation of NF-κB and MAPK Signaling Pathways by Sponging miR-5114.
Trametinib Inhibits the Growth and Aerobic Glycolysis of Glioma Cells by Targeting the PKM2/c-Myc Axis.
The Effect of Ellagic Acid on Hepatic Lipid Metabolism and Antioxidant Activity in Mice.
SARS-CoV-2 Nsp5 Activates NF-κB Pathway by Upregulating SUMOylation of MAVS.
Rhein Relieves Oxidative Stress in an Aβ(1-42) Oligomer-Burdened Neuron Model by Activating the SIRT1/PGC-1α-Regulated Mitochondrial Biogenesis.
Anlotinib Inhibits PFKFB3-Driven Glycolysis in Myofibroblasts to Reverse Pulmonary Fibrosis.
Identification of a Novel Gene Correlated With Vascular Smooth Muscle Cells Proliferation and Migration in Chronic Thromboembolic Pulmonary Hypertension.
Morchella importuna Flavones Improve Intestinal Integrity in Dextran Sulfate Sodium-Challenged Mice.
Probiotic Interventions Alleviate Food Allergy Symptoms Correlated With Cesarean Section: A Murine Model.
Paeoniflorin Suppresses TBHP-Induced Oxidative Stress and Apoptosis in Human Umbilical Vein Endothelial Cells via the Nrf2/HO-1 Signaling Pathway and Improves Skin Flap Survival.
Polysaccharides Extracted From Panax Ginseng C.A. Mey Enhance Complement Component 4 Biosynthesis in Human Hepatocytes.
Association of Pericyte Loss With Microthrombosis After Subarachnoid Hemorrhage in ApoE-Deficient Mice.
Identification of Potential Prognostic Biomarker for Predicting Survival in Multiple Myeloma Using Bioinformatics Analysis and Experiments.
The Downregulation of eIF3a Contributes to Vemurafenib Resistance in Melanoma by Activating ERK via PPP2R1B.
Inhibition of the Inflammasome Activity of NLRP3 Attenuates HDM-Induced Allergic Asthma.
Weighted Gene Co-Expression Network Analysis Identifies ANGPTL4 as a Key Regulator in Diabetic Cardiomyopathy via FAK/SIRT3/ROS Pathway in Cardiomyocyte.
Novel Pyrazolo[3,4-b] Pyridine Derivative (HLQ2g) Attenuates Hypoxic Pulmonary Hypertension via Restoring cGKI Expression and BMP Signaling Pathway.
miR-25 Regulates Gastric Cancer Cell Growth and Apoptosis by Targeting EGR2.
An Escherichia coli Effector Protein EspF May Induce Host DNA Damage via Interaction With SMC1.
Lidocaine Promoted Ferroptosis by Targeting miR-382-5p /SLC7A11 Axis in Ovarian and Breast Cancer.
Autophagy is Involved in Neuroprotective Effect of Alpha7 Nicotinic Acetylcholine Receptor on Ischemic Stroke.
c-Myc Upregulated by High Glucose Inhibits HaCaT Differentiation by S100A6 Transcriptional Activation.
High Mobility Group Box 1 (HMGB1) Induces Toll-Like Receptor 4-Mediated Production of the Immunosuppressive Protein Galectin-9 in Human Cancer Cells.
Effects of Sodium Ferulate on Cardiac Hypertrophy Are via the CaSR-Mediated Signaling Pathway.
SARS-CoV-2 Membrane Protein Inhibits Type I Interferon Production Through Ubiquitin-Mediated Degradation of TBK1.
Astragaloside IV Inhibits Galactose-Deficient IgA1 Secretion via miR-98-5p in Pediatric IgA Nephropathy.
Circ_0040039 May Aggravate Intervertebral Disk Degeneration by Regulating the MiR-874-3p-ESR1 Pathway.
A New Chalcone Derivative C49 Reverses Doxorubicin Resistance in MCF-7/DOX Cells by Inhibiting P-Glycoprotein Expression.
Nicotine Causes Mitochondrial Dynamics Imbalance and Apoptosis Through ROS Mediated Mitophagy Impairment in Cardiomyocytes.
Quercetin Attenuates Trauma-Induced Heterotopic Ossification by Tuning Immune Cell Infiltration and Related Inflammatory Insult.
TOX Acts as a Tumor Suppressor by Inhibiting mTOR Signaling in Colorectal Cancer.
Identification of a RAD52 Inhibitor Inducing Synthetic Lethality in BRCA2-Deficient Cancer Cells.
BYHWD Alleviates Inflammatory Response by NIK-Mediated Repression of the Noncanonical NF-κB Pathway During ICH Recovery.
Increased Angiogenin Expression Correlates With Radiation Resistance and Predicts Poor Survival for Patients With Nasopharyngeal Carcinoma.
Meteorin-Like Ameliorates β Cell Function by Inhibiting β Cell Apoptosis of and Promoting β Cell Proliferation via Activating the WNT/β-Catenin Pathway.
Duck Hepatitis A Virus Type 1 Induces eIF2α Phosphorylation-Dependent Cellular Translation Shutoff via PERK/GCN2.
In Vivo Inhibition of MicroRNA-326 in a NOD.H-2h4 Mouse Model of Autoimmune Thyroiditis.
IR-61 Improves Voiding Function via Mitochondrial Protection in Diabetic Rats.
Bortezomib Sustains T Cell Function by Inducing miR-155-Mediated Downregulation of SOCS1 and SHIP1.
Inhibition of Shear-Induced Platelet Aggregation by Xueshuantong via Targeting Piezo1 Channel-Mediated Ca2+ Signaling Pathway.
SFTSV Infection Induced Interleukin-1β Secretion Through NLRP3 Inflammasome Activation.
PHB2 promotes tumorigenesis via RACK1 in non-small cell lung cancer.
Necroptosis pathway blockage attenuates PFKFB3 inhibitor-induced cell viability loss and genome instability in colorectal cancer cells.
Targeting of glioma stem-like cells with a parthenolide derivative ACT001 through inhibition of AEBP1/PI3K/AKT signaling.
Local administration of liposomal-based Srpx2 gene therapy reverses pulmonary fibrosis by blockading fibroblast-to-myofibroblast transition.
KAT6A, a novel regulator of β-catenin, promotes tumorigenicity and chemoresistance in ovarian cancer by acetylating COP1.
Aurka loss in CD19+ B cells promotes megakaryocytopoiesis via IL-6/STAT3 signaling-mediated thrombopoietin production.
Ese-3 contributes to colon cancer progression by downregulating EHD2 and transactivating INPP4B.
Cardiac telocytes inhibit cardiac microvascular endothelial cell apoptosis through exosomal miRNA-21-5p-targeted cdip1 silencing to improve angiogenesis following myocardial infarction.
Autophagy-Induced HDAC6 Activity During Hypoxia Regulates Mitochondrial Energy Metabolism Through the β-Catenin/COUP-TFII Axis in Hepatocellular Carcinoma Cells.
Purified Vitexin Compound 1 Serves as a Promising Antineoplastic Agent in Ovarian Cancer.
Identification of Glycolysis-Related lncRNAs and the Novel lncRNA WAC-AS1 Promotes Glycolysis and Tumor Progression in Hepatocellular Carcinoma.
Honokiol Suppresses Perineural Invasion of Pancreatic Cancer by Inhibiting SMAD2/3 Signaling.
The Anti-Colon Cancer Effects of Essential Oil of Curcuma phaeocaulis Through Tumour Vessel Normalisation.
Downregulation of miR-142a Contributes to the Enhanced Anti-Apoptotic Ability of Murine Chronic Myelogenous Leukemia Cells.
Cystatin-B Negatively Regulates the Malignant Characteristics of Oral Squamous Cell Carcinoma Possibly Via the Epithelium Proliferation/Differentiation Program.
NEK7 Promotes Pancreatic Cancer Progression And Its Expression Is Correlated With Poor Prognosis.
Transcriptomic Analyses of the Adenoma-Carcinoma Sequence Identify Hallmarks Associated With the Onset of Colorectal Cancer.
The EIF4A3/CASC2/RORA Feedback Loop Regulates the Aggressive Phenotype in Glioblastomas.
Aeromonas sobria Induces Proinflammatory Cytokines Production in Mouse Macrophages via Activating NLRP3 Inflammasome Signaling Pathways.
Transcriptomic Analyses Reveal B-Cell Translocation Gene 2 as a Potential Therapeutic Target in Ovarian Cancer.
The RNA-Binding Protein NELFE Promotes Gastric Cancer Growth and Metastasis Through E2F2.
Long Non-Coding RNA LINC00467 Correlates to Poor Prognosis and Aggressiveness of Breast Cancer.
N6-Methyladenosine Modification of LncRNA DUXAP9 Promotes Renal Cancer Cells Proliferation and Motility by Activating the PI3K/AKT Signaling Pathway.
Downregulation of GLYAT Facilitates Tumor Growth and Metastasis and Poor Clinical Outcomes Through the PI3K/AKT/Snail Pathway in Human Breast Cancer.
MiR-454-3p Promotes Oxaliplatin Resistance by Targeting PTEN in Colorectal Cancer.
Asparagine Synthetase-Mediated l-Asparagine Metabolism Disorder Promotes the Perineural Invasion of Oral Squamous Cell Carcinoma.
Discovering and Characterizing of Survivin Dominant Negative Mutants With Stronger Pro-apoptotic Activity on Cancer Cells and CSCs.
HOXA5 Is Recognized as a Prognostic-Related Biomarker and Promotes Glioma Progression Through Affecting Cell Cycle.
TFEB Promotes Prostate Cancer Progression via Regulating ABCA2-Dependent Lysosomal Biogenesis.
Identification of Hub Genes Associated With Sensitivity of 5-Fluorouracil Based Chemotherapy for Colorectal Cancer by Integrated Bioinformatics Analysis.
IFN-γ facilitates liver fibrogenesis by CD161+CD4+ T cells through a regenerative IL-23/IL-17 axis in chronic hepatitis B virus infection.
Epigallocatechin-3-gallate inhibits proliferation and triggers apoptosis in colon cancer via the hedgehog/phosphoinositide 3-kinase pathways.
SARS-CoV-2 ORF9b antagonizes type I and III interferons by targeting multiple components of the RIG-I/MDA-5-MAVS, TLR3-TRIF, and cGAS-STING signaling pathways.
Subicular Caspase-1 Contributes to Pharmacoresistance in Temporal Lobe Epilepsy.
Yangonin modulates lipid homeostasis, ameliorates cholestasis and cellular senescence in alcoholic liver disease via activating nuclear receptor FXR.
Actin-binding protein, IQGAP1, regulates LPS-induced RPMVECs hyperpermeability and ICAM-1 upregulation via Rap1/Src signalling pathway.
HOXA5 induces M2 macrophage polarization to attenuate carotid atherosclerosis by activating MED1.
AIM2 forms a complex with pyrin and ZBP1 to drive PANoptosis and host defence.
Disruption of Circadian Clocks Promotes Progression of Alzheimer's Disease in Diabetic Mice.
Postconditioning with Sevoflurane or Propofol Alleviates Lipopolysaccharide-Induced Neuroinflammation but Exerts Dissimilar Effects on the NR2B Subunit and Cognition.
Melatonin and doxorubicin synergistically enhance apoptosis via autophagy-dependent reduction of AMPKα1 transcription in human breast cancer cells.
Bruton's tyrosine kinase regulates macrophage‑induced inflammation in the diabetic kidney via NLRP3 inflammasome activation.
Environmental Microcystin exposure in underlying NAFLD-induced exacerbation of neuroinflammation, blood-brain barrier dysfunction, and neurodegeneration are NLRP3 and S100B dependent.
Spata2 Knockdown Exacerbates Brain Inflammation via NF-κB/P38MAPK Signaling and NLRP3 Inflammasome Activation in Cerebral Ischemia/Reperfusion Rats.
Long noncoding RNA ANRIL knockdown attenuates neuroinflammation following ischemic stroke via suppressing the expression of NF-κB in vitro and in vivo.
KDELR2 promotes breast cancer proliferation via HDAC3-mediated cell cycle progression.
Gastrodin protects against high glucose-induced cardiomyocyte toxicity via GSK-3β-mediated nuclear translocation of Nrf2.
An Antioxidant Sesquiterpene Inhibits Osteoclastogenesis Via Blocking IPMK/TRAF6 and Counteracts OVX-Induced Osteoporosis in Mice.
Long non-coding RNA DUXAP9 promotes hepatocellular carcinoma cell stemness via directly interacting with sox9.
Compound essential oils relieve oxidative stress caused by PM2 .5 exposure by inhibiting autophagy through the AMPK/mTOR pathway.
CTR9-mediated JAK2/STAT3 pathway promotes the proliferation, migration, and invasion of human glioma cells.
MiR-100-5p regulates cardiac hypertrophy through activation of autophagy by targeting mTOR.
Bone marrow mesenchymal stem cell-derived exosomes induce the Th17/Treg imbalance in immune thrombocytopenia through miR-146a-5p/IRAK1 axis.
Bovine viral diarrhea virus NS4B protein interacts with 2CARD of MDA5 domain and negatively regulates the RLR-mediated IFN-β production.
Docosahexaenoic acid activates the Nrf2 signaling pathway to alleviate impairment of spleen cellular immunity in intrauterine growth restricted rat pups.
Cinnabar protects serum-nutrient starvation induced apoptosis by improving intracellular oxidative stress and inhibiting the expression of CHOP and PERK.
miR-29c-3p regulates TET2 expression and inhibits autophagy process in Parkinson's disease models.
DNM3OS regulates GAPDH expression and influences the molecular pathogenesis of Huntington's disease.
Exogenous H2 S prevents the nuclear translocation of PDC-E1 and inhibits vascular smooth muscle cell proliferation in the diabetic state.
Salusin‑β participates in high glucose‑induced HK‑2 cell ferroptosis in a Nrf‑2‑dependent manner.
Lack of Mof reduces acute liver injury by enhancing transcriptional activation of Igf1.
PKC-β/Alox5 axis activation promotes Bcr-Abl-independent TKI-resistance in chronic myeloid leukemia.
Propofol inhibited gastric cancer proliferation via the hsa-miR-328-3p/STAT3 pathway.
The piRNA pathway is essential for generating functional oocytes in golden hamsters.
RNA N6 -methyladenosine modification suppresses replication of rice black streaked dwarf virus and is associated with virus persistence in its insect vector.
Low-dose repeated exposure to chemical surfactant impairs corneal epithelium: When personal cleaning products entering the eye.
Hsa_circ_0006232 promotes laryngeal squamous cell cancer progression through FUS-mediated EZH2 stabilization.
Total Flavonoids of Engelhardia roxburghiana Wall. Leaves Alleviated Foam Cells Formation through AKT/mTOR-Mediated Autophagy in the Progression of Atherosclerosis.
High mobility group box 1 mediates inflammatory response of astrocytes via cyclooxygenase 2/prostaglandin E2 signaling following spinal cord injury.
Ruyiping extract reduces lung metastasis in triple negative breast cancer by regulating macrophage polarization.
Quadruple-editing of the MAPK and PI3K pathways effectively blocks the progression of KRAS-mutated colorectal cancer cells.
METTL14 promotes glomerular endothelial cell injury and diabetic nephropathy via m6A modification of α-klotho.
Genomic and epigenomic evolution of acquired resistance to combination therapy in esophageal squamous cell carcinoma.
Viral targeting of glioblastoma stem cells with patient-specific genetic and post-translational p53 deregulations.
A pair of long intergenic non-coding RNA LINC00887 variants act antagonistically to control Carbonic Anhydrase IX transcription upon hypoxia in tongue squamous carcinoma progression.
Cannabidiol Effectively Promoted Cell Death in Bladder Cancer and the Improved Intravesical Adhesion Drugs Delivery Strategy Could Be Better Used for Treatment.
ACLY ubiquitination by CUL3-KLHL25 induces the reprogramming of fatty acid metabolism to facilitate iTreg differentiation.
LncRNA-6395 promotes myocardial ischemia-reperfusion injury in mice through increasing p53 pathway.
Sema3A accelerates bone formation during distraction osteogenesis in mice.
Stimulation of ROS Generation by Extract of Warburgia ugandensis Leading to G0/G1 Cell Cycle Arrest and Antiproliferation in A549 Cells.
Identification and Characterization of Eimeria tenella Microneme Protein (EtMIC8).
HIF-1α/JMJD1A signaling regulates inflammation and oxidative stress following hyperglycemia and hypoxia-induced vascular cell injury.
Adipose expression of CREB3L3 modulates body weight during obesity.
Hexokinase 2-mediated glycolysis promotes receptor activator of NF-κB ligand expression in Porphyromonas gingivalis lipopolysaccharide-treated osteoblasts.
Exosomal microRNA-588 from M2 polarized macrophages contributes to cisplatin resistance of gastric cancer cells.
Dual Inhibition of Endoplasmic Reticulum Stress and Oxidation Stress Manipulates the Polarization of Macrophages under Hypoxia to Sensitize Immunotherapy.
Identification of genes and pathways leading to metastasis and poor prognosis in melanoma.
Regulatory variants at 2q33.1 confer schizophrenia risk by modulating distal gene TYW5 expression.
The Ginsenoside Rg1 Rescues Mitochondrial Disorders in Aristolochic Acid-Induced Nephropathic Mice.
Anti-osteosarcoma effect of antiserum against cross antigen TPD52 between osteosarcoma and Trichinella spiralis.
MEST promotes lung cancer invasion and metastasis by interacting with VCP to activate NF-κB signaling.
Differential expression of long non-coding RNAs in the hippocampus of mice exposed to PM2.5 in Dalian, China.
Potent Inhibition of HIF1α and p300 Interaction by a Constrained Peptide Derived from CITED2.
Discovery of a Potent Glutathione Peroxidase 4 Inhibitor as a Selective Ferroptosis Inducer.
Transgelin-2 interacts with CD44 to regulate Notch1 signaling pathway and participates in colorectal cancer proliferation and migration.
Perinatal low-dose bisphenol AF exposure impairs synaptic plasticity and cognitive function of adult offspring in a sex-dependent manner.
Genistein exhibits therapeutic potential for PCOS mice via the ER-Nrf2-Foxo1-ROS pathway.
Isonicotinylation is a histone mark induced by the anti-tuberculosis first-line drug isoniazid.
β-adrenergic receptor inhibition enhances oncolytic herpes virus propagation through STAT3 activation in gastric cancer.
Ultramicronized Palmitoylethanolamide Inhibits NLRP3 Inflammasome Expression and Pro-Inflammatory Response Activated by SARS-CoV-2 Spike Protein in Cultured Murine Alveolar Macrophages.
RIOK2 Inhibitor NSC139021 Exerts Anti-Tumor Effects on Glioblastoma via Inducing Skp2-Mediated Cell Cycle Arrest and Apoptosis.
Lactobacillus johnsonii L531 Alleviates the Damage Caused by Salmonella Typhimurium via Inhibiting TLR4, NF-κB, and NLRP3 Inflammasome Signaling Pathways.
KIF15 upregulation promotes leiomyosarcoma cell growth via promoting USP15-mediated DEK deubiquitylation.
UBE2S promotes the progression and Olaparib resistance of ovarian cancer through Wnt/β-catenin signaling pathway.
HSF1 is involved in suppressing A1 phenotype conversion of astrocytes following spinal cord injury in rats.
MiR-200c-3p promotes ox-LDL-induced endothelial to mesenchymal transition in human umbilical vein endothelial cells through SMAD7/YAP pathway.
Harmine-inspired design and synthesis of benzo[d]imidazo[2,1-b]thiazole derivatives bearing 1,3,4-oxadiazole moiety as potential tumor suppressors.
Hypoxia increases KIAA1199/CEMIP expression and enhances cell migration in pancreatic cancer.
Exogenous melatonin prevents type 1 diabetes mellitus-induced bone loss, probably by inhibiting senescence.
Genetically variant human pluripotent stem cells selectively eliminate wild-type counterparts through YAP-mediated cell competition.
Ketamine ameliorates depressive-like behaviors in mice through increasing glucose uptake regulated by the ERK/GLUT3 signaling pathway.
A standardized extract of Asparagus officinalis stem improves HSP70-mediated redox balance and cell functions in bovine cumulus-granulosa cells.
2,5-dimethyl celecoxib induces apoptosis and autophagy via activation of ROS/JNK axis in nasopharyngeal carcinoma cells.
Defining the Cholesterol Lowering Mechanism of Bergamot (Citrus bergamia) Extract in HepG2 and Caco-2 Cells.
Targeting chromosome trisomy for chromosome editing.
Baicalein Enhances the Effect of Acarbose on the Improvement of Nonalcoholic Fatty Liver Disease Associated with Prediabetes via the Inhibition of De Novo Lipogenesis.
H2S alleviates aortic aneurysm and dissection: Crosstalk between transforming growth factor 1 signaling and NLRP3 inflammasome.
Silica nanoparticles inhibiting the differentiation of round spermatid and chromatin remodeling of haploid period via MIWI in mice.
LncAY controls BMI1 expression and activates BMI1/Wnt/β-catenin signaling axis in hepatocellular carcinoma.
Sitagliptin attenuates endothelial dysfunction independent of its blood glucose controlling effect.
LncRNA OIP5-AS1 inhibits ferroptosis in prostate cancer with long-term cadmium exposure through miR-128-3p/SLC7A11 signaling.
Yeast Shells Encapsulating Adjuvant AS04 as an Antigen Delivery System for a Novel Vaccine against Toxoplasma Gondii.
Radiation-Induced Autophagy in Human Pancreatic Cancer Cells is Critically Dependent on G2 Checkpoint Activation: A Mechanism of Radioresistance in Pancreatic Cancer.
Sodium butyrate alleviates pre-eclampsia in pregnant rats by improving the gut microbiota and short-chain fatty acid metabolites production.
Ornithine decarboxylase of the fungal pathogen Colletotrichum higginsianum plays an important role in regulating global metabolic pathways and virulence.
JNK inhibition alleviates delayed neurocognitive recovery after surgery by limiting microglia pyroptosis.
Thymus quinquecostatus Celak. ameliorates cerebral ischemia-reperfusion injury via dual antioxidant actions: Activating Keap1/Nrf2/HO-1 signaling pathway and directly scavenging ROS.
Lactobacillus casei relieves liver injury by regulating immunity and suppression of the enterogenic endotoxin-induced inflammatory response in rats cotreated with alcohol and iron.
Characteristics and clinical significance of polyploid giant cancer cells in laryngeal carcinoma.
SETD3 Downregulation Mediates PTEN Upregulation-Induced Ischemic Neuronal Death Through Suppression of Actin Polymerization and Mitochondrial Function.
Systematic screening identifies a TEAD4-S100A13 axis modulating cisplatin sensitivity of oral squamous cell carcinoma cells.
Alpha-ketoglutarate ameliorates pressure overload-induced chronic cardiac dysfunction in mice.
CTHRC1 Knockdown Promotes Inflammatory Responses Partially by p38 MAPK Activation in Human Periodontal Ligament Cells.
Interleukin-38 Suppresses Cell Migration and Proliferation and Promotes Apoptosis of Colorectal Cancer Cell Through Negatively Regulating Extracellular Signal-Regulated Kinases Signaling.
High-mobility group AT-Hook 1 mediates the role of nuclear factor I/X in osteogenic differentiation through activating canonical Wnt signaling.
Autographa Californica Multiple Nucleopolyhedrovirus orf13 Is Required for Efficient Nuclear Egress of Nucleocapsids.
An enzyme-responsive Gp1a-hydrogel for skin wound healing.
Imbalanced inflammatory response in subchronic arsenic-induced liver injury and the protective effects of Ginkgo biloba extract in rats: Potential role of cytokines mediated cell-cell interactions.
5-IP7 is a GPCR messenger mediating neural control of synaptotagmin-dependent insulin exocytosis and glucose homeostasis.
Dynamin-related protein 1 regulates substrate oxidation in skeletal muscle by stabilizing cellular and mitochondrial calcium dynamics.
Arsenic Trioxide Combining Leflunomide Activates Nrf2-ARE-HO-1 Signaling Pathway and Protects Heart Xenografts.
MicroRNA ssc-miR-124a exhibits antiviral activity against porcine reproductive and respiratory syndrome virus via suppression of host genes CD163.
TRIM21 negatively regulates Corynebacterium pseudotuberculosis-induced inflammation and is critical for the survival of C. pseudotuberculosis infected C57BL6 mice.
Reactive oxygen species induced by uric acid promote NRK‑52E cell apoptosis through the NEK7‑NLRP3 signaling pathway.
Hsa_circ_0004058 inhibits apoptosis of SRA01/04 cells by promoting autophagy via miR-186/ATG7 axis.
Advanced Maternal Age-associated SIRT1 Deficiency Compromises Trophoblast Epithelial-Mesenchymal Transition through an Increase in Vimentin Acetylation.
Activation of angiotensin-converting enzyme 2/angiotensin (1-7)/mas receptor axis triggers autophagy and suppresses microglia proinflammatory polarization via forkhead box class O1 signaling.
Peptides derived from viral glycoprotein Gc Inhibit infection of severe fever with thrombocytopenia syndrome virus.
RSL3 enhances the antitumor effect of cisplatin on prostate cancer cells via causing glycolysis dysfunction.
PIKE-A promotes glioblastoma growth by driving PPP flux through increasing G6PD expression mediated by phosphorylation of STAT3.
Dihydroartemisinin regulates lipid droplet metabolism in hepatic stellate cells by inhibiting lncRNA-H19-induced AMPK signal.
LncRNA-Malat1 down-regulates miR-211-5p expression to promote neuronal damage from cerebral ischemia reperfusion injury.
Ginsenoside Rg1 prevents bone marrow mesenchymal stem cell senescence via NRF2 and PI3K/Akt signaling.
A purified human platelet pellet lysate rich in neurotrophic factors and antioxidants repairs and protects corneal endothelial cells from oxidative stress.
Deletion of ribosomal paralogs Rpl39 and Rpl39l compromises cell proliferation via protein synthesis and mitochondrial activity.
Design, synthesis and antitumor evaluation of novel chiral diaryl substituted azetidin-2-one derivatives as tubulin polymerization inhibitors.
Transcription factor POU4F2 promotes colorectal cancer cell migration and invasion through hedgehog-mediated epithelial-mesenchymal transition.
Aberrant expression of SNHG12 contributes to N, N-dimethylformamide-induced hepatic apoptosis both in short-term and long-term DMF exposure.
Protocols for Characterization of Cdk5 Kinase Activity.
CENPA promotes clear cell renal cell carcinoma progression and metastasis via Wnt/β-catenin signaling pathway.
sTNFRII-Fc modification protects human UC-MSCs against apoptosis/autophagy induced by TNF-α and enhances their efficacy in alleviating inflammatory arthritis.
Glycogen synthase kinase 3 drives thymocyte egress by suppressing β-catenin activation of Akt.
d-mannose attenuates lipopolysaccharide-induced osteolysis via CPT1A-Mediated lipid metabolic regulation in macrophages.
TDAG51 induces renal interstitial fibrosis through modulation of TGF-β receptor 1 in chronic kidney disease.
Sulforaphane downregulated fatty acid synthase and inhibited microtubule-mediated mitophagy leading to apoptosis.
Tetrahedral Framework Nucleic Acid Delivered RNA Therapeutics Significantly Attenuate Pancreatic Cancer Progression via Inhibition of CTR1-Dependent Copper Absorption.
PDCD4 Simultaneously Promotes Microglia Activation via PDCD4-MAPK-NF-κB Positive Loop and Facilitates Neuron Apoptosis During Neuroinflammation.
Leojaponin inhibits NLRP3 inflammasome activation through restoration of autophagy via upregulating RAPTOR phosphorylation.
p53 transcriptionally regulates SQLE to repress cholesterol synthesis and tumor growth.
PFP@PLGA/Cu12Sb4S13-mediated PTT ablates hepatocellular carcinoma by inhibiting the RAS/MAPK/MT-CO1 signaling pathway.
Newcastle disease virus degrades SIRT3 via PINK1-PRKN-dependent mitophagy to reprogram energy metabolism in infected cells.
FAIM regulates autophagy through glutaminolysis in lung adenocarcinoma.
Activation of G protein coupled estrogen receptor prevents chemotherapy-induced intestinal mucositis by inhibiting the DNA damage in crypt cell in an extracellular signal-regulated kinase 1- and 2- dependent manner.
ATP-binding cassette protein ABCF1 couples transcription and genome surveillance in embryonic stem cells through low-complexity domain.
Stigmasterol inhibits the progression of lung cancer by regulating retinoic acid-related orphan receptor C.
Fructus Ligustri Lucidi aqueous extract promotes calcium balance and short-chain fatty acids production in ovariectomized rats.
Dysfunctional lactate metabolism in human alveolar type II cells from idiopathic pulmonary fibrosis lung explant tissue.
Subtractive CRISPR screen identifies the ATG16L1/vacuolar ATPase axis as required for non-canonical LC3 lipidation.
FABP4 is an independent risk factor for lymph node metastasis and poor prognosis in patients with cervical cancer.
The overexpression of Tipe2 in CRC cells suppresses survival while endogenous Tipe2 accelerates AOM/DSS induced-tumor initiation.
Circular RNA circPRKCI contributes to malignant progression of T-cell acute lymphoblastic leukemia by modulating miR-20a-5p/SOX4 axis.
The IFN-inducible GTPase IRGB10 regulates viral replication and inflammasome activation during influenza A virus infection in mice.
Glaesserella parasuis serotype 4 HPS4-YC disrupts the integrity of the swine tracheal epithelial barrier and facilitates bacterial translocation.
Layered Double Hydroxide Nanoparticles with Osteogenic Effects as miRNA Carriers to Synergistically Promote Osteogenesis of MSCs.
The OPG/RANKL/RANK system modulates calcification of common carotid artery in simulated microgravity rats by regulating NF-κB pathway.
Metformin sensitises hepatocarcinoma cells to methotrexate by targeting dihydrofolate reductase.
ADAR1 restricts ZBP1-mediated immune response and PANoptosis to promote tumorigenesis.
Synapse development is regulated by microglial THIK-1 K+ channels.
Agrimoniin sensitizes pancreatic cancer to apoptosis through ROS-mediated energy metabolism dysfunction.
LncRNA LINC00152 promotes oral squamous cell carcinoma growth via enhancing Upstream Transcription Factor 1 mediated Mitochondrial Ribosomal Protein L52 transcription.
Targeting CDC7 potentiates ATR-CHK1 signaling inhibition through induction of DNA replication stress in liver cancer.
Aronia melanocarpa polysaccharide ameliorates inflammation and aging in mice by modulating the AMPK/SIRT1/NF-κB signaling pathway and gut microbiota.
Unexpected Implication of SRP and AGO2 in Parkinson's Disease: Involvement in Alpha-Synuclein Biogenesis.
Thromboxane A2 is involved in the development of hypertension in chronic kidney disease rats.
A systematic approach to decode the mechanism of Cornus in the treatment of hepatocellular carcinoma (HCC).
Antidepressant mechanism of catalpol: Involvement of the PI3K/Akt/Nrf2/HO-1 signaling pathway in rat hippocampus.
Pharmacological activation of SIRT1 by metformin prevented trauma-induced heterotopic ossification through inhibiting macrophage mediated inflammation.
TRIM46 contributes to high glucose-induced ferroptosis and cell growth inhibition in human retinal capillary endothelial cells by facilitating GPX4 ubiquitination.
The expression of IFN-β is suppressed by the viral 3D polymerase via its impact on PGAM5 expression during enterovirus D68 infection.
NLRP3 inflammasome blocked the glycolytic pathway via targeting to PKLR in arsenic-induced hepatic insulin resistance.
5-Aminonaphthalene derivatives as selective nonnucleoside nuclear receptor binding SET domain-protein 2 (NSD2) inhibitors for the treatment of multiple myeloma.
HBeAg mediates inflammatory functions of macrophages by TLR2 contributing to hepatic fibrosis.
The Timing and Effects of Low-Dose Ethanol Treatment on Acetaminophen-Induced Liver Injury.
Revisiting astrocyte to neuron conversion with lineage tracing in vivo.
The interaction of S100A16 and GRP78 actives endoplasmic reticulum stress-mediated through the IRE1α/XBP1 pathway in renal tubulointerstitial fibrosis.
Shift in MSL1 alternative polyadenylation in response to DNA damage protects cancer cells from chemotherapeutic agent-induced apoptosis.
Vezatin regulates seizures by controlling AMPAR-mediated synaptic activity.
Sitagliptin activates the p62-Keap1-Nrf2 signalling pathway to alleviate oxidative stress and excessive autophagy in severe acute pancreatitis-related acute lung injury.
Triiodothyronine ameliorates silica-induced pulmonary inflammation and fibrosis in mice.
Effects of Bacillus subtilis on jejunal integrity, redox status, and microbial composition of intrauterine growth restriction suckling piglets.
Catalpol Weakens Depressive-like Behavior in Mice with Streptozotocin-induced Hyperglycemia via PI3K/AKT/Nrf2/HO-1 Signaling Pathway.
GRIM-19 inhibits proliferation and induces apoptosis in a p53-dependent manner in colorectal cancer cells through the SIRT7/PCAF/MDM2 axis.
EPS8 supports pancreatic cancer growth by inhibiting BMI1 mediated proteasomal degradation of ALDH7A1.
Harpagide alleviate neuronal apoptosis and blood-brain barrier leakage by inhibiting TLR4/MyD88/NF-κB signaling pathway in Angiotensin II-induced microglial activation in vitro.
Antagonizing effects of curcumin against mercury-induced autophagic death and trace elements disorder by regulating PI3K/AKT and Nrf2 pathway in the spleen.
Cadmium promotes apoptosis and inflammation via the circ08409/miR-133a/TGFB2 axis in bovine mammary epithelial cells and mouse mammary gland.
Cellular OCIAD2 protein is a proviral factor for hepatitis C virus replication.
Switch receptor T3/28 improves long-term persistence and antitumor efficacy of CAR-T cells.
Nitrate increases cisplatin chemosensitivity of oral squamous cell carcinoma via REDD1/AKT signaling pathway.
Hsa-miR-372-5p regulates the NIMA related kinase 7 and IL-1β release in NK/T-cell lymphoma.
D-mannose alleviates osteoarthritis progression by inhibiting chondrocyte ferroptosis in a HIF-2α-dependent manner.
Curcumol inhibits the malignant progression of prostate cancer and regulates the PDK1/AKT/mTOR pathway by targeting miR‑9.
Interleukin-17 upregulation participates in the pathogenesis of heart failure in mice via NF-κB-dependent suppression of SERCA2a and Cav1.2 expression.
Oxidative stress-mediated apoptosis is involved in bisphenol S-induced reproductive toxicity in male C57BL/6 mice.
Propylparaben concentrations in the urine of women and adverse effects on ovarian function in mice in vivo and ovarian cells in vitro.
Proteasome inhibition induces macrophage apoptosis via mitochondrial dysfunction.
Rutaecarpine alleviates acute pancreatitis in mice and AR42J cells by suppressing the MAPK and NF-κB signaling pathways via calcitonin gene-related peptide.
Icariin attenuates renal fibrosis in chronic kidney disease by inhibiting interleukin-1β/transforming growth factor-β-mediated activation of renal fibroblasts.
NudCL2 is an autophagy receptor that mediates selective autophagic degradation of CP110 at mother centrioles to promote ciliogenesis.
A peptide CORO1C-47aa encoded by the circular noncoding RNA circ-0000437 functions as a negative regulator in endometrium tumor angiogenesis.
Environmental Pollutant Benzo[a]pyrene Upregulated Long Non-coding RNA HZ07 Inhibits Trophoblast Cell Migration by Inactivating PI3K/AKT/MMP2 Signaling Pathway in Recurrent Pregnancy Loss.
miR‑486‑5p suppresses gastric cancer cell growth and migration through downregulation of fibroblast growth factor 9.
Low-dose exposure to black carbon significantly increase lung injury of cadmium by promoting cellular apoptosis.
Gas6/Axl signaling pathway promotes proliferation, migration and invasion and inhibits apoptosis in A549 cells.
Metformin attenuates H(2)O(2)-induced osteoblast apoptosis by regulating SIRT3 via the PI3K/AKT pathway.
The anti-neoplastic activities of aloperine in HeLa cervical cancer cells are associated with inhibition of the IL-6-JAK1-STAT3 feedback loop.
Tau phosphorylation and OPA1 proteolysis are unrelated events: Implications for Alzheimer's Disease.
Chemical Constituents from the Rhizome of Ligusticum chuanxiong Hort. and Their Nrf2 Inducing Activity.
Chitotriosidase attenuates brain inflammation via HDAC3/NF-κB pathway in D-galactose and aluminum-induced rat model with cognitive impairments.
The differentiation state of the Schwann cell progenitor drives phenotypic variation between two contagious cancers.
Perfluorooctane sulfonate induces autophagy-dependent lysosomal membrane permeabilization by weakened interaction between tyrosinated alpha-tubulin and spinster 1.
Gastrodin promotes hippocampal neurogenesis via PDE9-cGMP-PKG pathway in mice following cerebral ischemia.
Comparative proteomics reveals Cryptosporidium parvum manipulation of the host cell molecular expression and immune response.
Trophoblast-derived interleukin 9 mediates immune cell conversion and contributes to maternal-fetal tolerance.
Dopamine receptor 2 downregulation and brain-derived neurotrophic factor upregulation in the paraventricular nucleus are correlated with brown adipose tissue thermogenesis in rats with bilateral substantia nigra lesions.
miRNA-223-3p modulates ibrutinib resistance through regulation of the CHUK/Nf-κb signaling pathway in mantle cell lymphoma.
Isoliquiritigenin alleviates LPS/ D-GalN-induced acute liver failure by activating the PGC-1α/ Nrf2 pathway to reduce oxidative stress and inflammatory response.
Functional role of galectin-9 in directing human innate immune reactions to Gram-negative bacteria and T cell apoptosis.
Ultrathin 2D Titanium Carbide MXene (Ti3 C2 Tx ) Nanoflakes Activate WNT/HIF-1α-Mediated Metabolism Reprogramming for Periodontal Regeneration.
DNMT1-induced miR-378a-3p silencing promotes angiogenesis via the NF-κB signaling pathway by targeting TRAF1 in hepatocellular carcinoma.
High throughput sequencing of whole transcriptome and construct of ceRNA regulatory network in RD cells infected with enterovirus D68.
The histone deacetylase inhibitor belinostat ameliorates experimental autoimmune encephalomyelitis in mice by inhibiting TLR2/MyD88 and HDAC3/ NF-κB p65-mediated neuroinflammation.
Betaine alleviates right ventricular failure via regulation of Rho A/ROCK signaling pathway in rats with pulmonary arterial hypertension.
Discovery of a potent MLL1 and WDR5 protein-protein interaction inhibitor with in vivo antitumor activity.
NOX4-derived ROS-induced overexpression of FOXM1 regulates aerobic glycolysis in glioblastoma.
Photobiomodulation inhibits the activation of neurotoxic microglia and astrocytes by inhibiting Lcn2/JAK2-STAT3 crosstalk after spinal cord injury in male rats.
FAK regulates cardiomyocyte mitochondrial fission and function through Drp1.
WFS1 functions in ER export of vesicular cargo proteins in pancreatic β-cells.
Alnustone inhibits the growth of hepatocellular carcinoma via ROS- mediated PI3K/Akt/mTOR/p70S6K axis.
Decreased efficacy of the ketamine and scopolamine-induced sustained antidepressant-like effects in rats receiving metformin.
Hyaluronic acid hydrogel encapsulated BMP-14-modified ADSCs accelerate cartilage defect repair in rabbits.
Taxifolin retards the D-galactose-induced aging process through inhibiting Nrf2-mediated oxidative stress and regulating the gut microbiota in mice.
Exosomes from dental pulp cells attenuate bone loss in mouse experimental periodontitis.
Golgi Phosphoprotein 3 Confers Radioresistance via Stabilizing EGFR in Lung Adenocarcinoma.
Structure-Based Discovery of Potent CARM1 Inhibitors for Solid Tumor and Cancer Immunology Therapy.
Proteolysis-Targeting Chimera (PROTAC) Modification of Dovitinib Enhances the Antiproliferative Effect against FLT3-ITD-Positive Acute Myeloid Leukemia Cells.
Carrier-Free Delivery of Ultrasmall π-Conjugated Oligomer Nanoparticles with Photothermal Conversion over 80% for Cancer Theranostics.
Knockdown of GBP1 inhibits BCG-induced apoptosis in macrophage RAW 264.7 cells via p38/JNK pathway.
The deubiquitinase USP28 stabilizes the expression of RecQ family helicases and maintains the viability of triple negative breast cancer cells.
Sorafenib attenuates liver fibrosis by triggering hepatic stellate cell ferroptosis via HIF-1α/SLC7A11 pathway.
Ginsenoside Rb1 alleviates diabetic kidney podocyte injury by inhibiting aldose reductase activity.
Cadmium attenuates testosterone synthesis by promoting ferroptosis and blocking autophagosome-lysosome fusion.
Effect of combination therapy with neural stem cell transplantation and teramethylpyrazine in rats following acute spinal cord injury.
HIF-1-regulated expression of calreticulin promotes breast tumorigenesis and progression through Wnt/β-catenin pathway activation.
MiR-29b-1-5p regulates the proliferation and differentiation of chicken primary myoblasts and analysis of its effective targets.
Sestrin2 induction contributes to anti-inflammatory responses and cell survival by globular adiponectin in macrophages.
Identification of proximal SUMO-dependent interactors using SUMO-ID.
Induction of estrogen receptor β-mediated autophagy sensitizes breast cancer cells to TAD1822-7, a novel biphenyl urea taspine derivative.
Fluoride Stimulates Anxiety- and Depression-like Behaviors Associated with SIK2-CRTC1 Signaling Dysfunction.
Dendrobium officinale Polysaccharide Alleviates Intestinal Inflammation by Promoting Small Extracellular Vesicle Packaging of miR-433-3p.
Role of Epigallocatechin Gallate in Glucose, Lipid, and Protein Metabolism and L-Theanine in the Metabolism-Regulatory Effects of Epigallocatechin Gallate.
Exopolysaccharides from Bifidobacterium animalis Ameliorate Escherichia coli-Induced IPEC-J2 Cell Damage via Inhibiting Apoptosis and Restoring Autophagy.
Ciliary Type III Adenylyl Cyclase in the VMH Is Crucial for High-Fat Diet-Induced Obesity Mediated by Autophagy.
Astragalus polysaccharide prevents ferroptosis in a murine model of experimental colitis and human Caco-2 cells via inhibiting NRF2/HO-1 pathway.
HMMR is a downstream target of FOXM1 in enhancing proliferation and partial epithelial-to-mesenchymal transition of bladder cancer cells.
3-Epipachysamine B suppresses proliferation and induces apoptosis of breast cancer cell via PI3K/AKT/mTOR signaling pathway.
Si-Wu-Tang facilitates ovarian function through improving ovarian microenvironment and angiogenesis in a mouse model of premature ovarian failure.
Protective effect of the effective part of Andrographis paniculata (Burm.f.) Nees on PM2.5-induced lung injury in rats by modulating the NF-κB pathway.
Yi-Qi-Jian-Pi formula modulates the PI3K/AKT signaling pathway to attenuate acute-on-chronic liver failure by suppressing hypoxic injury and apoptosis in vivo and in vitro.
Cutting Edge: Caspase-8 Is a Linchpin in Caspase-3 and Gasdermin D Activation to Control Cell Death, Cytokine Release, and Host Defense during Influenza A Virus Infection.
SARS-CoV-2 inhibits induction of the MHC class I pathway by targeting the STAT1-IRF1-NLRC5 axis.
Heat stress induces oxidative stress and activates the KEAP1-NFE2L2-ARE pathway in bovine endometrial epithelial cells†.
Xbp1s-Ddit3 promotes MCT-induced pulmonary hypertension.
The Mutational Landscape of PTK7 in Congenital Scoliosis and Adolescent Idiopathic Scoliosis.
Phase separation drives RNA virus-induced activation of the NLRP6 inflammasome.
The cytotoxicity of zinc oxide nanoparticles to 3D brain organoids results from excessive intracellular zinc ions and defective autophagy.
Erythritol Improves Nonalcoholic Fatty Liver Disease by Activating Nrf2 Antioxidant Capacity.
AICAR enhances the cytotoxicity of PFKFB3 inhibitor in an AMPK signaling-independent manner in colorectal cancer cells.
Isorhapontigenin (ISO) inhibits EMT through FOXO3A/METTL14/VIMENTIN pathway in bladder cancer cells.
SAA1 is transcriptionally activated by STAT3 and accelerates renal interstitial fibrosis by inducing endoplasmic reticulum stress.
Competing endogenous RNA network associated with oxygen-induced retinopathy: Expression of the network and identification of the MALAT1/miR-124-3p/EGR1 regulatory axis.
A naturally occurring FXR agonist, alisol B 23-acetate, protects against renal ischemia-reperfusion injury.
Vps13D functions in a Pink1-dependent and Parkin-independent mitophagy pathway.
Role of Lysocardiolipin Acyltransferase in Cigarette Smoke-Induced Lung Epithelial Cell Mitochondrial ROS, Mitochondrial Dynamics, and Apoptosis.
Deleterious impact of nerve growth factor precursor (proNGF) on bladder urothelial and smooth muscle cells.
Efficient Killing of Multidrug-Resistant Internalized Bacteria by AIEgens In Vivo.
Amelioration of Murine Macrophage Activation Syndrome by Monomethyl Fumarate in Both a Heme Oxygenase 1-Dependent and Heme Oxygenase 1-Independent Manner.
Elevated type I interferon responses potentiate metabolic dysfunction, inflammation, and accelerated aging in mtDNA mutator mice.
Novel Japanese encephalitis virus NS1-based vaccine: Truncated NS1 fused with E. coli heat labile enterotoxin B subunit.
Cu-induced mitochondrial dysfunction is mediated by abnormal mitochondrial fission through oxidative stress in primary chicken embryo hepatocytes.
Changes of lipid profiles in human umbilical vein endothelial cells exposed to zirconia nanoparticles with or without the presence of free fatty acids.
Comparison of toxicity of Ti3 C2 and Nb2 C Mxene quantum dots (QDs) to human umbilical vein endothelial cells.
Long non-coding RNA LEISA promotes progression of lung adenocarcinoma via enhancing interaction between STAT3 and IL-6 promoter.
miR-509-3p Suppresses Migration, Invasion, and Epithelial- Mesenchymal Transition in Melanoma Cells by Targeting Collagen Triple Helix Repeat Containing 1.
Cross-talk Between Histone and DNA Methylation Mediates Bone Loss in Hind Limb Unloading.
Long noncoding RNA DUXAP10 promotes the stemness of glioma cells by recruiting HuR to enhance Sox12 mRNA stability.
Glucose-dependent insulinotropic polypeptide modifies adipose plasticity and promotes beige adipogenesis of human omental adipose-derived stem cells.
Loss of ferroportin induces memory impairment by promoting ferroptosis in Alzheimer's disease.
Cholesterol 25-hydroxylase inhibits Senecavirus A replication by enzyme activity-dependent and independent mechanisms.
IL-1/IL-1R signaling induced by all-trans-retinal contributes to complement alternative pathway activation in retinal pigment epithelium.
Free Deoxycholic Acid Exacerbates Vascular Calcification in CKD through ER Stress-Mediated ATF4 Activation.
Long non-coding RNA PCA3 inhibits lipid accumulation and atherosclerosis through the miR-140-5p/RFX7/ABCA1 axis.
Anti-osteoporotic effects of alisol C 23-acetate via osteoclastogenesis inhibition.
SREBP1/FASN/cholesterol axis facilitates radioresistance in colorectal cancer.
Multi-omics approaches identify SF3B3 and SIRT3 as candidate autophagic regulators and druggable targets in invasive breast carcinoma.
The role of PKA/PP2B-mediated Drp1 phosphorylation and the subsequent EGFR inhibition in Cr(VI)-induced premature senescence.
De novo purine biosynthesis is a major driver of chemoresistance in glioblastoma.
Oxidative stress induced by NOX2 contributes to neuropathic pain via plasma membrane translocation of PKCε in rat dorsal root ganglion neurons.
Redd1 knockdown prevents doxorubicin-induced cardiac senescence.
Circular RNA Calm4 Regulates Hypoxia-Induced Pulmonary Arterial Smooth Muscle Cells Pyroptosis via the Circ-Calm4/miR-124-3p/PDCD6 Axis.
Evaluation of Stable LifeAct-mRuby2- and LAMP1-NeonGreen Expressing A549 Cell Lines for Investigation of Aspergillus fumigatus Interaction with Pulmonary Cells.
High-fat diet impairs ferroptosis and promotes cancer invasiveness via downregulating tumor suppressor ACSL4 in lung adenocarcinoma.
FKBP52 overexpression accelerates hippocampal-dependent memory impairments in a tau transgenic mouse model.
Ribonucleic Acid Export 1 Is a Kinetochore-Associated Protein That Participates in Chromosome Alignment in Mouse Oocytes.
Effect of circular RNA, mmu_circ_0000296, on neuronal apoptosis in chronic cerebral ischaemia via the miR-194-5p/Runx3/Sirt1 axis.
Oocyte-secreted factors strongly stimulate sFRP4 expression in human cumulus cells.
Lipoxin A4 protects primary spinal cord neurons from Erastin-induced ferroptosis by activating the Akt/Nrf2/HO-1 signaling pathway.
Vertebrate cells differentially interpret ciliary and extraciliary cAMP.
Genome-wide CRISPRi screening identifies OCIAD1 as a prohibitin client and regulatory determinant of mitochondrial Complex III assembly in human cells.
Evaluation of the nephrotoxicity and safety of low-dose aristolochic acid, extending to the use of Xixin (Asurum), by determination of methylglyoxal and d-lactate.
Downregulation of CD151 restricts VCAM-1 mediated leukocyte infiltration to reduce neurobiological injuries after experimental stroke.
Maternal folic acid supplementation prevents autistic behaviors in a rat model induced by prenatal exposure to valproic acid.
USP18 positively regulates innate antiviral immunity by promoting K63-linked polyubiquitination of MAVS.
The miR-378c-Samd1 circuit promotes phenotypic modulation of vascular smooth muscle cells and foam cells formation in atherosclerosis lesions.
Mir-139-5p inhibits glioma cell proliferation and progression by targeting GABRA1.
LncRNA ZNF674-AS1 regulates granulosa cell glycolysis and proliferation by interacting with ALDOA.
NT5DC2 promotes leiomyosarcoma tumour cell growth via stabilizing unpalmitoylated TEAD4 and generating a positive feedback loop.
Exercise improves lipid droplet metabolism disorder through activation of AMPK-mediated lipophagy in NAFLD.
SET8 mitigates hepatic ischemia/reperfusion injury in mice by suppressing MARK4/NLRP3 inflammasome pathway.
Purification, structural characterization, and PCSK9 secretion inhibitory effect of the novel alkali-extracted polysaccharide from Cordyceps militaris.
Asenapine maleate inhibits angiotensin II-induced proliferation and activation of cardiac fibroblasts via the ROS/TGFβ1/MAPK signaling pathway.
Hyperactivation of HER2-SHCBP1-PLK1 axis promotes tumor cell mitosis and impairs trastuzumab sensitivity to gastric cancer.
trans-Fatty acids promote p53-dependent apoptosis triggered by cisplatin-induced DNA interstrand crosslinks via the Nox-RIP1-ASK1-MAPK pathway.
A subcellular map of the human kinome.
Berberine-photodynamic therapy sensitizes melanoma cells to cisplatin-induced apoptosis through ROS-mediated P38 MAPK pathways.
High fat suppresses SOD1 activity by reducing copper chaperone for SOD1 associated with neurodegeneration and memory decline.
Short-term but not long-term high fat diet feeding protects against pressure overload-induced heart failure through activation of mitophagy.
6-Gingerol attenuates ventilator-induced lung injury via anti-inflammation and antioxidative stress by modulating the PPARγ/NF-κBsignalling pathway in rats.
Total glycosides from stems of Cistanche tubulosa alleviate depression-like behaviors: bidirectional interaction of the phytochemicals and gut microbiota.
Androgen Receptor Stimulates Hexokinase 2 and Induces Glycolysis by PKA/CREB Signaling in Hepatocellular Carcinoma.
Circadian clock genes promote glioma progression by affecting tumour immune infiltration and tumour cell proliferation.
Nbs1-mediated DNA damage repair pathway regulates haematopoietic stem cell development and embryonic haematopoiesis.
MiR-520a-3p inhibits malignant progression of epithelial ovarian cancer by targeting SUV39H1 expression.
Oncogenic AURKA-enhanced N6-methyladenosine modification increases DROSHA mRNA stability to transactivate STC1 in breast cancer stem-like cells.
Chondrocyte ferroptosis contribute to the progression of osteoarthritis.
miR-130b-3p regulates M1 macrophage polarization via targeting IRF1.
Apoptosis inhibition is involved in improvement of sevoflurane-induced cognitive impairment following normobaric hyperoxia preconditioning in aged rats.
Regulation of ARL2 in colorectal cancer cell proliferation and tumorigenicity, and its negative association with AXL.
Three phytosterols from sweet potato inhibit MCF7-xenograft-tumor growth through modulating gut microbiota homeostasis and SCFAs secretion.
d-Mannose suppresses osteoarthritis development in vivo and delays IL-1β-induced degeneration in vitro by enhancing autophagy activated via the AMPK pathway.
Gasdermin D Protects Mouse Podocytes Against High-Glucose-Induced Inflammation and Apoptosis via the C-Jun N-Terminal Kinase (JNK) Pathway.
Plumbagin, a Biomolecule with (Anti)Osteoclastic Properties.
Expression of Talin-1 in endometriosis and its possible role in pathogenesis.
lncRNA GCAT1 is involved in premature ovarian insufficiency by regulating p27 translation in GCs via competitive binding to PTBP1.
Combining combretastatin A4 phosphate with ginsenoside Rd synergistically inhibited hepatocellular carcinoma by reducing HIF-1α via PI3K/AKT/mTOR signalling pathway.
PUMA facilitates EMI1-promoted cytoplasmic Rad51 ubiquitination and inhibits DNA repair in stem and progenitor cells.
MYC promotes cancer progression by modulating m6 A modifications to suppress target gene translation.
The CREB/KMT5A complex regulates PTP1B to modulate high glucose-induced endothelial inflammatory factor levels in diabetic nephropathy.
Profiling PRMT methylome reveals roles of hnRNPA1 arginine methylation in RNA splicing and cell growth.
Hispidulin inhibits proliferation, migration, and invasion by promoting autophagy via regulation of PPARγ activation in prostate cancer cells and xenograft models.
Effects of transforming growth factor-β1 on odontoblastic differentiation in dental papilla cells is determined by IPO7 expression level.
hPER3 promotes adipogenesis via hHSP90AA1-mediated inhibition of Notch1 pathway.
Identifying SLC27A5 as a potential prognostic marker of hepatocellular carcinoma by weighted gene co-expression network analysis and in vitro assays.
PEG-GO@XN nanocomposite suppresses breast cancer metastasis via inhibition of mitochondrial oxidative phosphorylation and blockade of epithelial-to-mesenchymal transition.
PCGF3 promotes the proliferation and migration of non-small cell lung cancer cells via the PI3K/AKT signaling pathway.
The Effect of Hispidulin, a Flavonoid from Salvia plebeia, on Human Nasopharyngeal Carcinoma CNE-2Z Cell Proliferation, Migration, Invasion, and Apoptosis.
Citrus Alkaline Extracts Inhibit Senescence of A549 Cells to Alleviate Pulmonary Fibrosis via the β-Catenin/P53 Pathway.
Gastrodin ameliorates learning and memory impairment in rats with vascular dementia by promoting autophagy flux via inhibition of the Ca2+/CaMKII signal pathway.
Cytotoxicity mechanisms of plumbagin in drug-resistant tongue squamous cell carcinoma.
The deubiquitylase USP9X controls ribosomal stalling.
SZB120 Exhibits Immunomodulatory Effects by Targeting eIF2α to Suppress Th17 Cell Differentiation.
Melatonin inhibits vascular endothelial cell pyroptosis by improving mitochondrial function via up-regulation and demethylation of UQCRC1.
A novel peptide promotes human trophoblast proliferation and migration through PI3K/Akt/mTOR signaling pathway.
Ninjinyoeito improves anxiety behavior in neuropeptide Y deficient zebrafish.
Interleukin-24 as a Pulmonary Target Cytokine in Bronchopulmonary Dysplasia.
Promoterless, Nuclease-Free Genome Editing Confers a Growth Advantage for Corrected Hepatocytes in Mice With Methylmalonic Acidemia.
NCOA4-mediated ferritinophagy promoted inflammatory responses in periodontitis.
Sodium sulfite causes gastric mucosal cell death by inducing oxidative stress.
Golgi phosphoprotein 3 promotes the proliferation of gallbladder carcinoma cells via regulation of the NLRP3 inflammasome.
FMR1/circCHAF1A/miR-211-5p/HOXC8 feedback loop regulates proliferation and tumorigenesis via MDM2-dependent p53 signaling in GSCs.
SMAR1 attenuates the stemness of osteosarcoma cells via through suppressing ABCG2 transcriptional activity.
Small Interfering RNA Targeting DMP1 Protects Mice Against Blood-Brain Barrier Disruption and Brain Injury After Intracerebral Hemorrhage.
Cellular microRNAs influence replication of H3N2 canine influenza virus in infected cells.
Sparstolonin B exerts beneficial effects on prostate cancer by acting on the reactive oxygen species-mediated PI3K/AKT pathway.
Fructose-1,6-bisphosphatase aggravates oxidative stress-induced apoptosis in asthma by suppressing the Nrf2 pathway.
Phgdh serves a protective role in Il‑1β induced chondrocyte inflammation and oxidative‑stress damage.
Exploration of the hepatoprotective effect and mechanism of magnesium isoglycyrrhizinate in mice with arsenic trioxide‑induced acute liver injury.
Resveratrol sensitizes A549 cells to irradiation damage via suppression of store-operated calcium entry with Orai1 and STIM1 downregulation.
Differential expression of protein disulfide isomerase (PDI) in regulating endometrial receptivity in humans.
miR-29a-3p-dependent COL3A1 and COL5A1 expression reduction assists sulforaphane to inhibit gastric cancer progression.
RRx-001 ameliorates inflammatory diseases by acting as a potent covalent NLRP3 inhibitor.
Signal-regulatory protein alpha is an anti-viral entry factor targeting viruses using endocytic pathways.
SNX-3 mediates retromer-independent tubular endosomal recycling by opposing EEA-1-facilitated trafficking.
Paricalcitol inhibits oxidative stress-induced cell senescence of the bile duct epithelium dependent on modulating Sirt1 pathway in cholestatic mice.
Natural molecule Munronoid I attenuates LPS-induced acute lung injury by promoting the K48-linked ubiquitination and degradation of TAK1.
Tumor cell membrane-based peptide delivery system targeting the tumor microenvironment for cancer immunotherapy and diagnosis.
Long non-coding RNA muskelin 1 antisense RNA (MKLN1-AS) is a potential diagnostic and prognostic biomarker and therapeutic target for hepatocellular carcinoma.
Upregulation of ZHX2 predicts poor prognosis and is correlated with immune infiltration in gastric cancer.
Effect of SOCS3 on apoptosis of human trophoblasts via adjustment of the JAK2/STAT3 signaling pathway in preterm birth.
CDK5 positively regulates Notch1 signaling in pancreatic cancer cells by phosphorylation.
PBRM1 Cooperates with YTHDF2 to Control HIF-1α Protein Translation.
Epac activation ameliorates tubulointerstitial inflammation in diabetic nephropathy.
Multilevel regulation of Wnt signaling by Zic2 in colon cancer due to mutation of β-catenin.
The combination of CUDC-907 and gilteritinib shows promising in vitro and in vivo antileukemic activity against FLT3-ITD AML.
Hypericin-mediated photodynamic therapy inhibits growth of colorectal cancer cells via inducing S phase cell cycle arrest and apoptosis.
Cisplatin remodels the tumor immune microenvironment via the transcription factor EB in ovarian cancer.
The benzoate plant metabolite ethyl gallate prevents cellular- and vascular-lipid accumulation in experimental models of atherosclerosis.
Alisol A 24-acetate protects against brain microvascular endothelial cells injury through inhibiting miR-92a-3p/tight junctions axis.
Lactobacillus acidophilus ATCC 4356 Exopolysaccharides Suppresses Mediators of Inflammation through the Inhibition of TLR2/STAT-3/P38-MAPK Pathway in DEN-Induced Hepatocarcinogenesis in Rats.
Formin-like protein 2 promotes cell proliferation by a p27-related mechanism in human breast cancer cells.
Purification, characterization and anti-atherosclerotic effects of the polysaccharides from the fruiting body of Cordyceps militaris.
Self-stabilizing regulation of deubiquitinating enzymes in an enzymatic activity-dependent manner.
Breast tumor stiffness instructs bone metastasis via maintenance of mechanical conditioning.
Neu1 deficiency induces abnormal emotional behavior in zebrafish.
Thymosin β4 reverses phenotypic polarization of glial cells and cognitive impairment via negative regulation of NF-κB signaling axis in APP/PS1 mice.
The Anti-Tumor Effect and Underlying Apoptotic Mechanism of Ginsenoside Rk1 and Rg5 in Human Liver Cancer Cells.
DUSP1 overexpression attenuates renal tubular mitochondrial dysfunction by restoring Parkin-mediated mitophagy in diabetic nephropathy.
LncRNA CARMN overexpression promotes prognosis and chemosensitivity of triple negative breast cancer via acting as miR143-3p host gene and inhibiting DNA replication.
Binding of Benzo[a]pyrene Alters the Bioreactivity of Fine Biochar Particles toward Macrophages Leading to Deregulated Macrophagic Defense and Autophagy.
LINC00842 inactivates transcription co-regulator PGC-1α to promote pancreatic cancer malignancy through metabolic remodelling.
LINC_00355 promotes gastric cancer progression by upregulating PHF19 expression through sponging miR-15a-5p.
Colorectal cancer cells utilize autophagy to maintain mitochondrial metabolism for cell proliferation under nutrient stress.
Isorhamnetin Promotes Estrogen Biosynthesis and Proliferation in Porcine Granulosa Cells via the PI3K/Akt Signaling Pathway.
Protective effect of scorpion venom heat-resistant synthetic peptide against PM2.5-induced microglial polarization via TLR4-mediated autophagy activating PI3K/AKT/NF-κB signaling pathway.
HIF-2α activation potentiates oxidative cell death in colorectal cancers by increasing cellular iron.
Aerobic Exercise Improves Mitochondrial Function in Sarcopenia Mice Through Sestrin2 in an AMPKα2-Dependent Manner.
The engineered expression of secreted HSPB5-Fc in CHO cells exhibits cytoprotection in vitro.
Protective effects of 4-octyl itaconate against inflammatory response in angiotensin II-induced oxidative stress in human primary retinal pigment epithelium.
Protective Effects of Bone Marrow Mesenchymal Stem Cells (BMMSCS) Combined with Normothermic Machine Perfusion on Liver Grafts Donated After Circulatory Death via Reducing the Ferroptosis of Hepatocytes.
Central nervous system-targeted adeno-associated virus gene therapy in methylmalonic acidemia.
CSNK2A1-mediated phosphorylation of HMGA2 modulates cisplatin resistance in cervical cancer.
LncRNA CTD-2528L19.6 prevents the progression of IPF by alleviating fibroblast activation.
Resveratrol and its derivative pterostilbene ameliorate intestine injury in intrauterine growth-retarded weanling piglets by modulating redox status and gut microbiota.
A comparison expression analysis of CXCR4, CXCL9 and Caspase-9 in dermal vascular endothelial cells between keloids and normal skin on chemotaxis and apoptosis.
Tumors exploit FTO-mediated regulation of glycolytic metabolism to evade immune surveillance.
Galectin-9 Targets NLRP3 for Autophagic Degradation to Limit Inflammation.
Butyrate enhances CPT1A activity to promote fatty acid oxidation and iTreg differentiation.
25-Hydroxycholesterol mitigates hepatic ischemia reperfusion injury via mediating mitophagy.
Targeting TSP-1 decreased periodontitis by attenuating extracellular matrix degradation and alveolar bone destruction.
Pirfenidone mediates cigarette smoke extract induced inflammation and oxidative stress in vitro and in vivo.
A neutral polysaccharide from Ophiocordyceps lanpingensis restrains cisplatin-induced nephrotoxicity.
YAP/TEAD4-induced KIF4A contributes to the progression and worse prognosis of esophageal squamous cell carcinoma.
Thioredoxin-1 Rescues MPP+/MPTP-Induced Ferroptosis by Increasing Glutathione Peroxidase 4.
miR-671-5p Attenuates Neuroinflammation via Suppressing NF-κB Expression in an Acute Ischemic Stroke Model.
DHCR24 Knockdown Lead to Hyperphosphorylation of Tau at Thr181, Thr231, Ser262, Ser396, and Ser422 Sites by Membrane Lipid-Raft Dependent PP2A Signaling in SH-SY5Y Cells.
Hawthorn polyphenols, D-chiro-inositol, and epigallocatechin gallate exert a synergistic hypoglycemic effect.
EZH2 regulates expression of FOXC1 by mediating H3K27me3 in breast cancers.
The role of the HIF-1α/ALYREF/PKM2 axis in glycolysis and tumorigenesis of bladder cancer.
Sestrin2 protects against traumatic brain injury by reinforcing the activation of Nrf2 signaling.
Targeted radioimmunotherapy with the iodine-131-labeled caerin 1.1 peptide for human anaplastic thyroid cancer in nude mice.
Hepcidin sequesters iron to sustain nucleotide metabolism and mitochondrial function in colorectal cancer epithelial cells.
TCDD induced lipid accumulation by impairment of autophagic flux in THP-1 macrophages.
TLR2 senses the SARS-CoV-2 envelope protein to produce inflammatory cytokines.
Effect of the interference with DRP1 expression on the biological characteristics of glioma stem cells.
A conserved ubiquitin- and ESCRT-dependent pathway internalizes human lysosomal membrane proteins for degradation.
C1orf61 promotes hepatocellular carcinoma metastasis and increases the therapeutic response to sorafenib.
Visfatin regulates Pg LPS-induced proinflammatory/prodegradative effects in healthy and inflammatory periodontal cells partially via NF-κB pathway.
Ets-2 deletion in myeloid cells attenuates IL-1α-mediated inflammatory disease caused by a Ptpn6 point mutation.
DENV NS1 and MMP-9 cooperate to induce vascular leakage by altering endothelial cell adhesion and tight junction.
Chemical conjugation of FITC to track silica nanoparticles in vivo and in vitro: An emerging method to assess the reproductive toxicity of industrial nanomaterials.
Andrographolide Attenuates Gut-Brain-Axis Associated Pathology in Gulf War Illness by Modulating Bacteriome-Virome Associated Inflammation and Microglia-Neuron Proinflammatory Crosstalk.
ets1 associates with KMT5A to participate in high glucose-mediated EndMT via upregulation of PFN2 expression in diabetic nephropathy.
Inhibition of xCT suppresses the efficacy of anti-PD-1/L1 melanoma treatment through exosomal PD-L1-induced macrophage M2 polarization.
Baicalein Delays H2O2-Induced Astrocytic Senescence through Inhibition of Senescence-Associated Secretory Phenotype (SASP), Suppression of JAK2/STAT1/NF-κB Pathway, and Regulation of Leucine Metabolism.
Piperlongumine inhibits migration and proliferation of castration-resistant prostate cancer cells via triggering persistent DNA damage.
Baicalein inhibits RLS3-induced ferroptosis in melanocytes.
Melatonin alleviates Ochratoxin A-induced liver inflammation involved intestinal microbiota homeostasis and microbiota-independent manner.
mPEG2k-PCLx Polymeric Micelles Influence Pharmacokinetics and Hypoglycemic Efficacy of Metformin through Inhibition of Organic Cation Transporters in Rats.
The intrinsic role and mechanism of tumor expressed-CD38 on lung adenocarcinoma progression.
Probiotic-fermented black tartary buckwheat alleviates hyperlipidemia and gut microbiota dysbiosis in rats fed with a high-fat diet.
L-Theanine regulates glutamine metabolism and immune function by binding to cannabinoid receptor 1.
NR1D1 suppressed the growth of ovarian cancer by abrogating the JAK/STAT3 signaling pathway.
Glycoursodeoxycholic acid ameliorates diet-induced metabolic disorders with inhibiting endoplasmic reticulum stress.
Subregion-Specific Regulation of Dopamine D1 Receptor Signaling in the Striatum: Implication for L-DOPA-Induced Dyskinesia.
Growth Hormone Receptor (GHR) 6Ω Pseudoexon Activation: a Novel Cause of Severe Growth Hormone Insensitivity.
HELLS serves as a poor prognostic biomarker and its downregulation reserves the malignant phenotype in pancreatic cancer.
Serum exosomes from young rats improve the reduced osteogenic differentiation of BMSCs in aged rats with osteoporosis after fatigue loading in vivo.
Integrated analysis of m6A mRNA methylation in rats with monocrotaline-induced pulmonary arterial hypertension.
Effects of Loblolly Pine Biochar and Wood Vinegar on Poultry Litter Nutrients and Microbial Abundance.
REM Sleep Deprivation Impairs Learning and Memory by Decreasing Brain O-GlcNAc Cycling in Mouse.
Phenethylamine in chlorella alleviates high-fat diet-induced mouse liver damage by regulating generation of methylglyoxal.
Hypoxic preconditioning rejuvenates mesenchymal stem cells and enhances neuroprotection following intracerebral hemorrhage via the miR-326-mediated autophagy.
VALD-3, a Schiff base ligand synthesized from o-vanillin derivatives, induces cell cycle arrest and apoptosis in breast cancer cells by inhibiting the Wnt/β-catenin pathway.
Lactate secreted by PKM2 upregulation promotes Galectin-9-mediated immunosuppression via inhibiting NF-κB pathway in HNSCC.
Expression and significance of let-7a and tumor necrosis factor-alpha in placenta of severe preeclampsia.
Spodoptera frugiperda mRNA export factor interacts with and mediates the nuclear import of Autographa californica multiple nucleopolyhedrovirus ORF34 (Ac34).
Establishment of a specific in vivo Cu(Ⅰ) reporting system based on metallothionein screening.
The critical role of B4GALT4 in promoting microtubule spindle assembly in HCC through the regulation of PLK1 and RHAMM expression.
Potential effect of EGCG on the anti-tumor efficacy of metformin in melanoma cells.
Decreased expression of the clock gene Bmal1 is involved in the pathogenesis of temporal lobe epilepsy.
p53 deficiency induces MTHFD2 transcription to promote cell proliferation and restrain DNA damage.
Cyclophilin A Inhibits Human Respiratory Syncytial Virus (RSV) Replication by Binding to RSV-N through Its PPIase Activity.
Stimuli-Responsive and Highly Penetrable Nanoparticles as a Multifunctional Nanoplatform for Boosting Nonsmall Cell Lung Cancer siRNA Therapy.
Activation of Adenosine A1 Receptor in Ischemic Stroke: Neuroprotection by Tetrahydroxy Stilbene Glycoside as an Agonist.
The ZMYND8-regulated mevalonate pathway endows YAP-high intestinal cancer with metabolic vulnerability.
Evaluating the protective effects of individual or combined ginsenoside compound K and the downregulation of soluble epoxide hydrolase expression against sodium valproate-induced liver cell damage.
MicroRNA-363-3p promotes apoptosis in response to cadmium-induced renal injury by down-regulating phosphoinositide 3-kinase expression.
p55PIK deficiency and its NH2-terminal derivative inhibit inflammation and emphysema in COPD mouse model.
Novel functional variants in the Notch pathway and survival of Chinese colorectal cancer.
Alterations of GABA B receptors in the APP/PS1 mouse model of Alzheimer's disease.
Identification and validation of L Antigen Family Member 3 as an immune-related biomarker associated with the progression of papillary thyroid cancer.
Postnatal overfeeding induces hepatic microRNA-221 expression and impairs the PI3K/AKT pathway in adult male rats.
Uncaria rhynchophylla ameliorates unpredictable chronic mild stress-induced depression in mice via activating 5-HT1A receptor: Insights from transcriptomics.
Regulation of branched-chain amino acid metabolism by hypoxia-inducible factor in glioblastoma.
miR-937-5p targets SOX17 to modulate breast cancer cell cycle and cell proliferation through the Wnt signaling pathway.
Isoorientin exerts a urate-lowering effect through inhibition of xanthine oxidase and regulation of the TLR4-NLRP3 inflammasome signaling pathway.
Layer-specific strain for assessing the effect of naringin on systolic myocardial dysfunction induced by sepsis and its underlying mechanisms.
Esomeprazole overcomes paclitaxel-resistance and enhances anticancer effects of paclitaxel by inducing autophagy in A549/Taxol cells.
Topotecan induces hepatocellular injury via ASCT2 mediated oxidative stress.
Small extracellular vesicles containing miR-30a-3p attenuate the migration and invasion of hepatocellular carcinoma by targeting SNAP23 gene.
FBW7-NRA41-SCD1 axis synchronously regulates apoptosis and ferroptosis in pancreatic cancer cells.
Senolytic therapy ameliorates renal fibrosis postacute kidney injury by alleviating renal senescence.
Neuropathy-associated histidyl-tRNA synthetase variants attenuate protein synthesis in vitro and disrupt axon outgrowth in developing zebrafish.
Arsenic exposure increased expression of HOTAIR and LincRNA-p21 in vivo and vitro.
CircRNA-vgll3 promotes osteogenic differentiation of adipose-derived mesenchymal stem cells via modulating miRNA-dependent integrin α5 expression.
SNHG1 represses the anti-cancer roles of baicalein in cervical cancer through regulating miR-3127-5p/FZD4/Wnt/β-catenin signaling.
Endogenous promoter-driven sgRNA for monitoring the expression of low-abundance transcripts and lncRNAs.
Protection against Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice by Neferine, A Natural Product from Nelumbo nucifera Gaertn.
Quantitative proteomics reveals stage-specific protein regulation of triple negative breast cancer.
Loss of WD2 subdomain of Apaf-1 forms an apoptosome structure which blocks activation of caspase-3 and caspase-9.
Characteristics of inflammation process in monocrotaline-induced pulmonary arterial hypertension in rats.
Improved BMP2-CPC-stimulated osteogenesis in vitro and in vivo via modulation of macrophage polarization.
Hyperglycemia-reduced NAD+ biosynthesis impairs corneal epithelial wound healing in diabetic mice.
MiR-362 suppresses cervical cancer progression via directly targeting BAP31 and activating TGFβ/Smad pathway.
Identification of an N6-methyladenosine-mediated positive feedback loop that promotes Epstein-Barr virus infection.
Androgen receptor splicing variant 7 (ARV7) inhibits docetaxel sensitivity by inactivating the spindle assembly checkpoint.
The ATPase ATP6V1A facilitates rabies virus replication by promoting virion uncoating and interacting with the viral matrix protein.
Protective Effect of Retrograde Reperfusion Against Hepatic Autophagy Impairment in Rat Liver Transplantation.
The EGFR-HSF1 axis accelerates the tumorigenesis of pancreatic cancer.
Identification of the atypical cadherin FAT1 as a novel glypican-3 interacting protein in liver cancer cells.
Cell surface GRP78 regulates BACE2 via lysosome-dependent manner to maintain mesenchymal phenotype of glioma stem cells.
Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes.
β-Conglycinin induces the formation of neutrophil extracellular traps dependent on NADPH oxidase-derived ROS, PAD4, ERK1/2 and p38 signaling pathways in mice.
Yangonin inhibits ethanol-induced hepatocyte senescence via miR-194/FXR axis.
Progranulin induces immune escape in breast cancer via up-regulating PD-L1 expression on tumor-associated macrophages (TAMs) and promoting CD8+ T cell exclusion.
NEO100 enables brain delivery of blood‒brain barrier impermeable therapeutics.
Effect of Pregnane X Receptor on CYP3A29 Expression in Porcine Alveolar Macrophages during Mycoplasma hyopneumoniae Infection.
Effects of different concentrations of coated nano zinc oxide material on fecal bacterial composition and intestinal barrier in weaned piglets.
ADAM15 Participates in Tick-Borne Encephalitis Virus Replication.
Angiogenesis is promoted by exosomal DPP4 derived from 5-fluorouracil-resistant colon cancer cells.
Absolute configuration of tetrandrine and isotetrandrine influences their anti-proliferation effects in human T cells via different regulation of NF-κB.
Arsenite induce neurotoxicity of common carp: Involvement of blood brain barrier, apoptosis and autophagy, and subsequently relieved by zinc (Ⅱ) supplementation.
MicroRNA-193a-5p Regulates the Synthesis of Polyunsaturated Fatty Acids by Targeting Fatty Acid Desaturase 1 (FADS1) in Bovine Mammary Epithelial Cells.
Circular RNA circRUNX1 promotes papillary thyroid cancer progression and metastasis by sponging MiR-296-3p and regulating DDHD2 expression.
Diosmetin Ameliorates Nonalcoholic Steatohepatitis through Modulating Lipogenesis and Inflammatory Response in a STAT1/CXCL10-Dependent Manner.
Perampanel Stimulates Mitochondrial Biogenesis in Neuronal Cells through Activation of the SIRT1/PGC-1α Signaling Pathway.
Downregulation of metabotropic glutamate receptor 5 alleviates central sensitization by activating autophagy via inhibiting mTOR pathway in a rat model of chronic migraine.
Mutations in GDAP1 Influence Structure and Function of the Trans-Golgi Network.
Synergism of HPV and MNNG repress miR-218 promoting Het-1A cell malignant transformation by targeting GAB2.
Hypoxic conditioned promotes the proliferation of human olfactory mucosa mesenchymal stem cells and relevant lncRNA and mRNA analysis.
Microcystin-leucine arginine induced the apoptosis of GnRH neurons by activating the endoplasmic reticulum stress resulting in a decrease of serum testosterone level in mice.
Zinc offers splenic protection through suppressing PERK/IRE1-driven apoptosis pathway in common carp (Cyprinus carpio) under arsenic stress.
Curcumin ameliorates mercuric chloride-induced liver injury via modulating cytochrome P450 signaling and Nrf2/HO-1 pathway.
iASPP protects the heart from ischemia injury by inhibiting p53 expression and cardiomyocyte apoptosis.
Salvia miltiorrhiza stems and leaves total phenolic acids combination with tanshinone protect against DSS-induced ulcerative colitis through inhibiting TLR4/PI3K/AKT/mTOR signaling pathway in mice.
Aptamer-based CRISPR/Cas12a assay for the ultrasensitive detection of extracellular vesicle proteins.
An identified PfHMGB1 promotes microcystin-LR-induced liver injury of yellow catfish (Pelteobagrus fulvidraco).
The impact of SAMHD1 expression and mutation status in mantle cell lymphoma: An analysis of the MCL Younger and Elderly trial.
Role of Slit2 upregulation in recurrent miscarriage through regulation of stromal decidualization.
mTORC1-mediated amino acid signaling is critical for cell fate determination under transplant-induced stress.
Mutation analysis of MFSD8 in an amyotrophic lateral sclerosis cohort from mainland China.
lncRNA NEAT1 ameliorates LPS‑induced inflammation in MG63 cells by activating autophagy and suppressing the NLRP3 inflammasome.
The miR-145-5p/CD36 pathway mediates PCB2-induced apoptosis in MCF-7 cells.
Hypoxia-induced PLOD1 overexpression contributes to the malignant phenotype of glioblastoma via NF-κB signaling.
Activation of the G Protein-Coupled Estrogen Receptor Prevented the Development of Acute Colitis by Protecting the Crypt Cell.
TAR DNA-Binding Protein 43 is Cleaved by the Protease 3C of Enterovirus A71.
Enhancer II-targeted dsRNA decreases GDNF expression via histone H3K9 trimethylation to inhibit glioblastoma progression.
Upregulated Nmnat2 causes neuronal death and increases seizure susceptibility in temporal lobe epilepsy.
Piezo2 channel in nodose ganglia neurons is essential in controlling hypertension in a pathway regulated directly by Nedd4-2.
Triptolide inhibits epithelial-mesenchymal transition phenotype through the p70S6k/GSK3/β-catenin signaling pathway in taxol-resistant human lung adenocarcinoma.
Tregs facilitate obesity and insulin resistance via a Blimp-1/IL-10 axis.
NOGOB receptor-mediated RAS signaling pathway is a target for suppressing proliferating hemangioma.
Angiomotin Counteracts the Negative Regulatory Effect of Host WWOX on Viral PPxY-Mediated Egress.
Fork head box M1 regulates vascular endothelial growth factor-A expression to promote the angiogenesis and tumor cell growth of gallbladder cancer.
Hypoxic pancreatic stellate cell-derived exosomal mirnas promote proliferation and invasion of pancreatic cancer through the PTEN/AKT pathway.
Human drug efflux transporter ABCC5 confers acquired resistance to pemetrexed in breast cancer.
Exosomes in ovarian cancer ascites promote epithelial-mesenchymal transition of ovarian cancer cells by delivery of miR-6780b-5p.
Impaired Intestinal Akkermansia muciniphila and Aryl Hydrocarbon Receptor Ligands Contribute to Nonalcoholic Fatty Liver Disease in Mice.
Comparison of content-toxicity-activity of six ingenane-type diterpenoids between Euphorbia kansui before and after stir-fried with vinegar by using UFLC-MS/MS, zebrafish embryos and HT-29 cells.
Small extracellular vesicle-mediated Hsp70 intercellular delivery enhances breast cancer adriamycin resistance.
Differential mitochondrial proteomic analysis of A549 cells infected with avian influenza virus subtypes H5 and H9.
Polyamine Analog Diethylnorspermidine Restricts Coxsackievirus B3 and Is Overcome by 2A Protease Mutation In Vitro.
Down-regulation of A3AR signaling by IL-6-induced GRK2 activation contributes to Th17 cell differentiation.
Circ_0119872 promotes uveal melanoma development by regulating the miR-622/G3BP1 axis and downstream signalling pathways.
The long noncoding RNA KTN1-AS1 promotes bladder cancer tumorigenesis via KTN1 cis-activation and the consequent initiation of Rho GTPase-mediated signaling.
Protective role of serpina3c as a novel thrombin inhibitor against atherosclerosis in mice.
QiShenYiQi pill activates autophagy to attenuate reactive myocardial fibrosis via the PI3K/AKT/mTOR pathway.
Diosgenin alleviates hypercholesterolemia via SRB1/CES-1/CYP7A1/FXR pathway in high-fat diet-fed rats.
A novel tonicity-responsive microRNA miR-23a-5p modulates renal cell survival under osmotic stress through targeting heat shock protein 70 HSPA1B.
NF-κB pathway play a role in SCD1 deficiency-induced ceramide de novo synthesis.
Vascular endothelial cell-secreted exosomes facilitate osteoarthritis pathogenesis by promoting chondrocyte apoptosis.
Red ginseng has stronger anti-aging effects compared to ginseng possibly due to its regulation of oxidative stress and the gut microbiota.
IL-27 signalling promotes adipocyte thermogenesis and energy expenditure.
CoCrMo-Nanoparticles induced peri-implant osteolysis by promoting osteoblast ferroptosis via regulating Nrf2-ARE signalling pathway.
Identification of autophagic target RAB13 with small-molecule inhibitor in low-grade glioma via integrated multi-omics approaches coupled with virtual screening of traditional Chinese medicine databases.
Semaglutide attenuates seizure severity and ameliorates cognitive dysfunction by blocking the NLR family pyrin domain containing 3 inflammasome in pentylenetetrazole‑kindled mice.
Endoplasmic reticulum stress pathway mediates T-2 toxin-induced chondrocyte apoptosis.
FOXO1 inhibits prostate cancer cell proliferation via suppressing E2F1 activated NPRL2 expression.
GLO 1 and PKCλ Regulate ALDH1-positive Breast Cancer Stem Cell Survival.
The transcribed ultraconserved element uc.51 promotes the proliferation and metastasis of breast cancer by stabilizing NONO.
ubtor Mutation Causes Motor Hyperactivity by Activating mTOR Signaling in Zebrafish.
The flavonoid procyanidin C1 has senotherapeutic activity and increases lifespan in mice.
Caspase-6 promotes activation of the caspase-11-NLRP3 inflammasome during gram-negative bacterial infections.
MEHP induces pyroptosis and autophagy alternation by cathepsin B activation in INS-1 cells.
A bivalent cyclic RGD-siRNA conjugate enhances the antitumor effect of apatinib via co-inhibiting VEGFR2 in non-small cell lung cancer xenografts.
Exosomal ANXA2 derived from ovarian cancer cells regulates epithelial-mesenchymal plasticity of human peritoneal mesothelial cells.
FPR2 serves a role in recurrent spontaneous abortion by regulating trophoblast function via the PI3K/AKT signaling pathway.
Knockdown of TRIM9 attenuates irinotecan‑induced intestinal mucositis in IEC‑6 cells by regulating DUSP6 expression via the P38 pathway.
Suppression of ER-stress induction of GRP78 as an anti-neoplastic mechanism of the cardiac glycoside Lanatoside C in pancreatic cancer: Lanatoside C suppresses GRP78 stress induction.
Danshensu derivative ADTM ameliorates CCl4‑induced acute liver injury in mice through inhibiting oxidative stress and apoptosis.
Mel1b and Mel1c melatonin receptors mediate green light-induced secretion of growth hormone in chick adenohypophysis cells via the AC/PKA and ERK1/2 signalling pathways.
Arsenic (III) induces oxidative stress and inflammation in the gills of common carp, which is ameliorated by zinc (II).
Knockdown of METTL14 suppresses the malignant progression of non-small cell lung cancer by reducing Twist expression.
CMPK2 accelerates liver ischemia/reperfusion injury via the NLRP3 signaling pathway.
Antidepressant effect of catalpol on corticosterone-induced depressive-like behavior involves the inhibition of HPA axis hyperactivity, central inflammation and oxidative damage probably via dual regulation of NF-κB and Nrf2.
Small molecule targeting topoisomerase 3β for cancer therapy.
Dihydroartemisinin ameliorates retinal vascular dysfunction in diabetes mellitus via the FASN/Kmal-mTOR/SREBP1 feedback loop.
DNA damage-inducible transcript 3 restrains osteoclast differentiation and function.
Acupuncture regulates the autophagy of ovarian granulosa cells in polycystic ovarian syndrome ovulation disorder by inhibiting the PI3K/AKT/mTOR pathway through LncMEG3.
Selenoprotein S attenuates high glucose and/or ox-LDL-induced endothelium injury by regulating Akt/mTOR signaling and autophagy.
Silencing FYVE, RhoGEF, and PH domain containing 1 (FGD1) suppresses melanoma progression by inhibiting PI3K/AKT signaling pathway.
Role of Rho guanine nucleotide exchange factors in non-small cell lung cancer.
Mechanistic insights into the renoprotective role of curcumin in cisplatin-induced acute kidney injury: network pharmacology analysis and experimental validation.
Human umbilical vein endothelial cells derived-exosomes promote osteosarcoma cell stemness by activating Notch signaling pathway.
A comprehensive genome-wide analysis of long non-coding RNA and mRNA expression profiles of JAK2V617F-positive classical myeloproliferative neoplasms.
A virulent Bacillus cereus strain from deep-sea cold seep induces pyroptosis in a manner that involves NLRP3 inflammasome, JNK pathway, and lysosomal rupture.
ATR kinase activity promotes antibody class switch recombination in B cells through cell cycle regulation without suppressing DSB resection and microhomology usage.
GABAA receptor agonist muscimol rescues inhibitory microcircuit defects in the olfactory bulb and improves olfactory function in APP/PS1 transgenic mice.
1β-Hydroxyalantolactone from Inulae Flos alleviated the progression of pulmonary fibrosis via inhibiting JNK/FOXO1/NF-κB pathway.
Dietary hawthorn-leaves flavonoids improves ovarian function and liver lipid metabolism in aged breeder hens.
Mannan-binding lectin deficiency augments hepatic endoplasmic reticulum stress through IP3R-controlled calcium release.
Acquiring high expression of suilysin enable non-epidemic Streptococccus suis to cause streptococcal toxic shock-like syndrome (STSLS) through NLRP3 inflammasome hyperactivation.
Oligomeric Aβ25-35 induces the tyrosine phosphorylation of PSD-95 by SrcPTKs in rat hippocampal CA1 subfield.
MiRNA-132/212 regulates tight junction stabilization in blood-brain barrier after stroke.
NLRP3 inflammasome signal pathway involves in Vibrio harveyi-induced inflammatory response in murine peritoneal macrophages in vitro.
Transcriptional regulator CTR9 promotes hepatocellular carcinoma progression and metastasis via increasing PEG10 transcriptional activity.
ZNF382 controls mouse neuropathic pain via silencer-based epigenetic inhibition of Cxcl13 in DRG neurons.
Diacerein attenuates vascular dysfunction by reducing inflammatory response and insulin resistance in type 2 diabetic rats.
CD38 activation by monosodium urate crystals contributes to inflammatory responses in human and murine macrophages.
USP30-AS1 contributes to mitochondrial quality control in glioblastoma cells.
Heat stress affects fetal brain and intestinal function associated with the alterations of placental barrier in late pregnant mouse.
Interleukin-37 inhibits inflammation activation and disease severity of PM2.5-induced airway hyperresponsiveness.
Nucleosomes enter cells by clathrin- and caveolin-dependent endocytosis.
Evaluating the Effect of Lenvatinib on Sorafenib-Resistant Hepatocellular Carcinoma Cells.
A distributed residue network permits conformational binding specificity in a conserved family of actin remodelers.
Probiotic Bacillus cereus Alleviates Dextran Sulfate Sodium-Induced Colitis in Mice through Improvement of the Intestinal Barrier Function, Anti-Inflammation, and Gut Microbiota Modulation.
Tangeretin maintains antioxidant activity by reducing CUL3 mediated NRF2 ubiquitination.
Carnosol alleviates nonalcoholic fatty liver disease by inhibiting mitochondrial dysfunction and apoptosis through targeting of PRDX3.
Involvement of endoplasmic reticulum stress-activated PERK-eIF2α-ATF4 signaling pathway in T-2 toxin-induced apoptosis of porcine renal epithelial cells.
PAX5-activated lncRNA ARRDC1-AS1 accelerates the autophagy and progression of DLBCL through sponging miR-2355-5p to regulate ATG5.
Ketamine enhances novel object recognition memory reconsolidation via the BDNF/TrkB pathway in mice.
Role of the hippo signaling pathway in the extracellular matrix degradation of chondrocytes induced by fluoride exposure.
Cypermethrin triggers YY1-mediated testosterone biosynthesis suppression.
Quercetin reverses chronic unpredictable mild stress-induced depression-like behavior in vivo by involving nuclear factor-E2-related factor 2.
ATF6-mediated unfolded protein response facilitates AAV2 transduction by releasing the suppression of AAV receptor on ER stress.
Metformin alleviates hydrogen peroxide-induced inflammation and oxidative stress via inhibiting P2X7R signaling in spinal cord tissue cells neurons.
AKR1C3 decreased CML sensitivity to Imatinib in bone marrow microenvironment via dysregulation of miR-379-5p.
Heat shock protein 90 inhibitor ameliorates pancreatic fibrosis by degradation of transforming growth factor-β receptor.
Microglial Calhm2 regulates neuroinflammation and contributes to Alzheimer's disease pathology.
Rapid generation of maternal mutants via oocyte transgenic expression of CRISPR-Cas9 and sgRNAs in zebrafish.
The intervention of intestinal Wnt/β-catenin pathway alters inflammation and disease severity of CIA.
Milk Polar Lipids Supplementation to Obese Rats During Pregnancy and Lactation Benefited Skeletal Outcomes of Male Offspring.
H. pylori infection induces CXCL8 expression and promotes gastric cancer progress through downregulating KLF4.
Exosomal miR-193b-5p as a regulator of LPS-induced inflammation in dairy cow mammary epithelial cells.
Circadian misalignment promotes vascular smooth muscle cell apoptosis via defective autophagy.
Progranulin promotes osteogenic differentiation of periodontal membrane stem cells in both inflammatory and non-inflammatory conditions.
Lipocalin-2: a role in hepatic gluconeogenesis via AMP-activated protein kinase (AMPK).
Hepatoprotective effects of loach (Misgurnus anguillicaudatus) lyophilized powder on dimethylnitrosamine-induced liver fibrosis in rats.
Chicoric acid attenuates hyperglycemia-induced endothelial dysfunction through AMPK-dependent inhibition of oxidative/nitrative stresses.
W436, a novel SMART derivative, exhibits anti-hepatocarcinoma activity by inducing apoptosis and G2/M cell cycle arrest in vitro and in vivo and induces protective autophagy.
Immunization with recombinant Erns-LTB fusion protein elicits protective immune responses against bovine viral diarrhea virus.
Downregulation of SUN2 promotes metastasis of colon cancer by activating BDNF/TrkB signalling by interacting with SIRT1.
Procyanidin B2 alleviates liver injury caused by cold stimulation through Sonic hedgehog signalling and autophagy.
LncRNA MAYA promotes iron overload and hepatocyte senescence through inhibition of YAP in non-alcoholic fatty liver disease.
CircPLCE1 facilitates the malignant progression of colorectal cancer by repressing the SRSF2-dependent PLCE1 pre-RNA splicing.
Fisetin mitigates hepatic ischemia-reperfusion injury by regulating GSK3β/AMPK/NLRP3 inflammasome pathway.
DDIT3/CHOP promotes autophagy in chondrocytes via SIRT1-AKT pathway.
Targeting P2RX1 alleviates renal ischemia/reperfusion injury by preserving mitochondrial dynamics.
Ferroptosis inducer erastin sensitizes NSCLC cells to celastrol through activation of the ROS-mitochondrial fission-mitophagy axis.
Momordin Ic induces G0/1 phase arrest and apoptosis in colon cancer cells by suppressing SENP1/c-MYC signaling pathway.
The active ingredients and mechanisms of Longchai Jiangxue Formula in treating PV, based on UPLC/Q-TOF-MS/MS, systematic pharmacology, and molecular biology validation.
Systematic investigation of the pharmacological mechanism for renal protection by the leaves of Eucommia ulmoides Oliver using UPLC-Q-TOF/MS combined with network pharmacology analysis.
Grouper TRAF5 exerts negative regulation on antiviral immune response against iridovirus.
Bone morphogenetic protein-7 inhibits endothelial-to-mesenchymal transition in primary human umbilical vein endothelial cells and mouse model of systemic sclerosis via Akt/mTOR/p70S6K pathway.
Melatonin mediates monochromatic light-induced expression of somatostatin in the hypothalamus and pituitary of chicks.
Suramin attenuates intervertebral disc degeneration by inhibiting NF-κB signalling pathway.
Extract of Cynomorium songaricum ameliorates mitochondrial ultrastructure impairments and dysfunction in two different in vitro models of Alzheimer's disease.
Metformin Is a Pyridoxal-5'-phosphate (PLP)-Competitive Inhibitor of SHMT2.
TRIM28 SUMOylates and stabilizes NLRP3 to facilitate inflammasome activation.
Association of CASC18/miR-20a-3p/TGFB2 ceRNA axis with occult lymph node metastasis in tongue squamous cell carcinoma.
DEAD-box helicase 27 enhances stem cell-like properties with poor prognosis in breast cancer.
METTL3 regulates PM2.5-induced cell injury by targeting OSGIN1 in human airway epithelial cells.
Mammalian target of rapamycin signaling pathway is involved in synaptic plasticity of the spinal dorsal horn and neuropathic pain in rats by regulating autophagy.
circBTBD7 Promotes Immature Porcine Sertoli Cell Growth through Modulating miR-24-3p/MAPK7 Axis to Inactivate p38 MAPK Signaling Pathway.
Targeting Amino Acid Metabolic Reprogramming via L-Type Amino Acid Transporter 1 (LAT1) for Endocrine-Resistant Breast Cancer.
The COL-4A1 polypeptide destroy endothelial cells through the TGF-β/PI3K/AKT pathway.
Protection of pancreatic β-cell by phosphocreatine through mitochondrial improvement via the regulation of dual AKT/IRS-1/GSK-3β and STAT3/Cyp-D signaling pathways.
CCT5 interacts with cyclin D1 promoting lung adenocarcinoma cell migration and invasion.
Association of T2285C polymorphism in PARP1 gene coding region with its expression, activity and NSCLC risk along with prognosis.
Glyceraldehyde-3-Phosphate Dehydrogenase Restricted in Cytoplasmic Location by Viral GP5 Facilitates Porcine Reproductive and Respiratory Syndrome Virus Replication via Its Glycolytic Activity.
Hepatoprotective effect of anemoside B4 against sepsis-induced acute liver injury through modulating the mTOR/p70S6K-mediated autophagy.
Ten-eleven translocation 1 mediated-DNA hydroxymethylation is required for myelination and remyelination in the mouse brain.
Osthole inhibits the migration and invasion of highly metastatic breast cancer cells by suppressing ITGα3/ITGβ5 signaling.
Circular RNA CircEYA3 induces energy production to promote pancreatic ductal adenocarcinoma progression through the miR-1294/c-Myc axis.
HIF-1α-activated TM4SF1-AS1 promotes the proliferation, migration, and invasion of hepatocellular carcinoma cells by enhancing TM4SF1 expression.
Advanced oxidation protein products impair autophagic flux in macrophage by inducing lysosomal dysfunction via activation of PI3K-Akt-mTOR pathway in Crohn's disease.
MicroRNA-138-1-3p sensitizes sorafenib to hepatocellular carcinoma by targeting PAK5 mediated β-catenin/ABCB1 signaling pathway.
Polysaccharides from Ulva prolifera O.F. Müller inhibit cell proliferation via activating MAPK signaling in A549 and H1650 cells.
Antitumor Effects of Astaxanthin on Esophageal Squamous Cell Carcinoma by up-Regulation of PPARγ.
IL-22 Downregulates Peptidylarginine Deiminase-1 in Human Keratinocytes: Adding Another Piece to the IL-22 Puzzle in Epidermal Barrier Formation.
Ceruloplasmin correlates with immune infiltration and serves as a prognostic biomarker in breast cancer.
Silibinin Suppresses Tumor Cell-Intrinsic Resistance to Nintedanib and Enhances Its Clinical Activity in Lung Cancer.
Serum DJ-1 Is a Biomarker of Colorectal Cancer and DJ-1 Activates Mitophagy to Promote Colorectal Cancer Progression.
Large-scale and high-resolution mass spectrometry-based proteomics profiling defines molecular subtypes of esophageal cancer for therapeutic targeting.
In vitro assessment of a synergistic combination of gemcitabine and zebularine in pancreatic cancer cells.
Microtubule associated protein 4 (MAP4) phosphorylation reduces cardiac microvascular density through NLRP3-related pyroptosis.
KAT2A-mediated AR translocation into nucleus promotes abiraterone-resistance in castration-resistant prostate cancer.
Metformin attenuates renal tubulointerstitial fibrosis via upgrading autophagy in the early stage of diabetic nephropathy.
Nervous Necrosis Virus Coat Protein Mediates Host Translation Shutoff through Nuclear Translocalization and Degradation of Polyadenylate Binding Protein.
Ophiocordyceps lanpingensis polysaccharides alleviate chronic kidney disease through MAPK/NF-κB pathway.
LncRNA LINC00680 promotes lung adenocarcinoma growth via binding to GATA6 and canceling GATA6-mediated suppression of SOX12 expression.
Empagliflozin, a sodium glucose cotransporter-2 inhibitor, ameliorates peritoneal fibrosis via suppressing TGF-β/Smad signaling.
Ergosterol peroxide exhibits antiviral and immunomodulatory abilities against porcine deltacoronavirus (PDCoV) via suppression of NF-κB and p38/MAPK signaling pathways in vitro.
LncRNA ABCC6P1 promotes proliferation and migration of papillary thyroid cancer cells via Wnt/β-catenin signaling pathway.
Limonin induces apoptosis of HL-60 cells by inhibiting NQO1 activity.
Melatonin Ameliorates Lipopolysaccharide-Induced Microglial Inflammation via Triggering SIRT1/HMGB1 Signaling Axis.
Pooled CRISPR screening identifies m6A as a positive regulator of macrophage activation.
Bio-inspired chiral self-assemblies promoted neuronal differentiation of retinal progenitor cells through activation of metabolic pathway.
Perilipin 4 Protein: an Impending Target for Amyotrophic Lateral Sclerosis.
Inhibition of soluble epoxide hydrolase (sEH) protects hippocampal neurons and reduces cognitive decline in type 2 diabetic mice.
Expression of lncRNA CCAT2 in children with neuroblastoma and its effect on cancer cell growth.
Induction of NUPR1 and AP‑1 contributes to the carcinogenic potential of nickel.
Anti-thrombotic activity of phenolic acids obtained from Salvia miltiorrhiza f. alba in TNF-α-stimulated endothelial cells via the NF-κB/JNK/p38 MAPK signaling pathway.
miR-182-5p and miR-96-5p Target PIAS1 and Mediate the Negative Feedback Regulatory Loop between PIAS1 and STAT3 in Endometrial Cancer.
CRISPR/Cas9 library screening uncovered methylated PKP2 as a critical driver of lung cancer radioresistance by stabilizing β-catenin.
The orphan nuclear receptor Nurr1 agonist amodiaquine mediates neuroprotective effects in 6-OHDA Parkinson's disease animal model by enhancing the phosphorylation of P38 mitogen-activated kinase but not PI3K/AKT signaling pathway.
Programmed cell death 4 modulates lysosomal function by inhibiting TFEB translation.
ARFGAP1 binds to classical swine fever virus NS5A protein and enhances CSFV replication in PK-15 cells.
MARCH5 restores endothelial cell function against ischaemic/hypoxia injury via Akt/eNOS pathway.
Method used to establish a large animal model of drug-induced acute kidney injury.
Postnatal growth retardation is associated with deteriorated intestinal mucosal barrier function using a porcine model.
[Effect of astragaloside IV on the expression of NOD-like receptor protein 3 inflammasome in neonatal rats with hypoxic-ischemic brain damage].
LncIHAT Is Induced by Hypoxia-Inducible Factor 1 and Promotes Breast Cancer Progression.
Cigarette smoke extract amplifies NADPH oxidase-dependent ROS production to inactivate PTEN by oxidation in BEAS-2B cells.
Low-dose naltrexone plays antineoplastic role in cervical cancer progression through suppressing PI3K/AKT/mTOR pathway.
The S100 calcium-binding protein A11 promotes hepatic steatosis through RAGE-mediated AKT-mTOR signaling.
Resveratrol Attenuates Meningitic Escherichia coli-Mediated Blood-Brain Barrier Disruption.
PolyQ-expanded proteins impair cellular proteostasis of ataxin-3 through sequestering the co-chaperone HSJ1 into aggregates.
Absence of TNF Leads to Alternative Activation in Peritoneal Macrophages in Experimental Listeria Monocytogenes Infection.
Methylene blue prevents osteoarthritis progression and relieves pain in rats via upregulation of Nrf2/PRDX1.
N(6)-methyladenosine-binding protein YTHDF1 suppresses EBV replication and promotes EBV RNA decay.
ASIC1 and ASIC3 mediate cellular senescence of human nucleus pulposus mesenchymal stem cells during intervertebral disc degeneration.
EGFR-ERK induced activation of GRHL1 promotes cell cycle progression by up-regulating cell cycle related genes in lung cancer.
Interleukin-17A mediates tobacco smoke-induced lung cancer epithelial-mesenchymal transition through transcriptional regulation of ΔNp63α on miR-19.
miR-190 promotes malignant transformation and progression of human urothelial cells through CDKN1B/p27 inhibition.
Pterostilbene, a Dimethylether Analogue of Resveratrol, Possesses High Potency in the Prevention of Platelet Activation in Humans and the Reduction of Vascular Thrombosis in Mice.
Fludarabine Inhibits Infection of Zika Virus, SFTS Phlebovirus, and Enterovirus A71.
Dynamic evolution of emphysema and airway remodeling in two mouse models of COPD.
Leukemia inhibitory factor regulates Schwann cell proliferation and migration and affects peripheral nerve regeneration.
Circ11103 Interacts with miR-128/PPARGC1A to Regulate Milk Fat Metabolism in Dairy Cows.
H2O2 enhances the anticancer activity of TMPyP4 by ROS-mediated mitochondrial dysfunction and DNA damage.
Buprenorphine alters microglia and astrocytes acutely following diffuse traumatic brain injury.
CK2 Activity Mediates the Aggressive Molecular Signature of Glioblastoma Multiforme by Inducing Nerve/Glial Antigen (NG)2 Expression.
Identification of a mesenchymal-related signature associated with clinical prognosis in glioma.
Btk knockout attenuates the liver inflammation in STZ-induced diabetic mice by suppressing NLRP3 inflammasome activation.
An IgD-Fc-Ig fusion protein restrains the activation of T and B cells by inhibiting IgD-IgDR-Lck signaling in rheumatoid arthritis.
Differential Expression of CB1 Cannabinoid Receptor and Cannabinoid Receptor Interacting Protein 1a in Labor.
Chemoproteomics-enabled discovery of covalent RNF114-based degraders that mimic natural product function.
Loss of Mitochondrial Protease CLPP Activates Type I IFN Responses through the Mitochondrial DNA-cGAS-STING Signaling Axis.
AKR1B10 negatively regulates autophagy through reducing GAPDH upon glucose starvation in colon cancer.
Kisspeptin-10 Maintains the Activation of the mTOR Signaling Pathway by Inhibiting SIRT6 to Promote the Synthesis of Milk in Bovine Mammary Epithelial Cells.
AIF3 splicing switch triggers neurodegeneration.
An Experimentally Induced Mutation in the UBA Domain of p62 Changes the Sensitivity of Cisplatin by Up-Regulating HK2 Localisation on the Mitochondria and Increasing Mitophagy in A2780 Ovarian Cancer Cells.
Nonsegmented Negative-Sense RNA Viruses Utilize N 6-Methyladenosine (m6A) as a Common Strategy To Evade Host Innate Immunity.
Kaempferol induces ROS-dependent apoptosis in pancreatic cancer cells via TGM2-mediated Akt/mTOR signaling.
Effect of Shuangdan Mingmu capsule, a Chinese herbal formula, on oxidative stress-induced apoptosis of pericytes through PARP/GAPDH pathway.
TET1 may contribute to hypoxia-induced epithelial to mesenchymal transition of endometrial epithelial cells in endometriosis.
Lycopene alleviates oxidative stress via the PI3K/Akt/Nrf2pathway in a cell model of Alzheimer's disease.
Tethering of Telomeres to the Nuclear Envelope Is Mediated by SUN1-MAJIN and Possibly Promoted by SPDYA-CDK2 During Meiosis.
Enterohemorrhagic Escherichia coli Effector Protein EspF Interacts With Host Protein ANXA6 and Triggers Myosin Light Chain Kinase (MLCK)-Dependent Tight Junction Dysregulation.
Safrana l Prevents Prostate Cancer Recurrence by Blocking the Re-activation of Quiescent Cancer Cells via Downregulation of S-Phase Kinase-Associated Protein 2.
miR-7-5p Affects Brain Edema After Intracerebral Hemorrhage and Its Possible Mechanism.
Amnion-Derived Mesenchymal Stem Cell Exosomes-Mediated Autophagy Promotes the Survival of Trophoblasts Under Hypoxia Through mTOR Pathway by the Downregulation of EZH2.
C2C12 Mouse Myoblasts Damage Induced by Oxidative Stress Is Alleviated by the Antioxidant Capacity of the Active Substance Phloretin.
Ferroptosis-Related Gene Signature Predicts Glioma Cell Death and Glioma Patient Progression.
miR-205 Expression Elevated With EDS Treatment and Induced Leydig Cell Apoptosis by Targeting RAP2B via the PI3K/AKT Signaling Pathway.
Ketamine ameliorates hypoxia-induced endothelial injury in human umbilical vein endothelial cells.
Cdk5 Inhibitory Peptide Prevents Loss of Neurons and Alleviates Behavioral Changes in p25 Transgenic Mice.
Maternal Methyl-Donor Micronutrient Supplementation During Pregnancy Promotes Skeletal Muscle Differentiation and Maturity in Newborn and Weaning Pigs.
Potential Role of SLC5A8 Expression in the Etiology of Subacute Ruminal Acidosis.
miR-124-3p Suppresses the Invasiveness and Metastasis of Hepatocarcinoma Cells via Targeting CRKL.
MicroRNA-362-3p Inhibits Migration and Invasion via Targeting BCAP31 in Cervical Cancer.
Metformin effectively treats Tsc1 deletion-caused kidney pathology by upregulating AMPK phosphorylation.
miR-143-3p inhibition promotes neuronal survival in an Alzheimer's disease cell model by targeting neuregulin-1.
Modulation of Wnt/β-catenin signaling in IL-17A-mediated macrophage polarization of RAW264.7 cells.
Antrodia Cinnamomea Attenuates Non-Alcoholic Steatohepatitis by Suppressing NLRP3 Inflammasome Activation In Vitro and In Vivo.
Koumine Alleviates Lipopolysaccharide-Induced Intestinal Barrier Dysfunction in IPEC-J2 Cells by Regulating Nrf2/NF-κ
Osthole Improves Cognitive Function of Vascular Dementia Rats: Reducing Aβ Deposition via Inhibition NLRP3 Inflammasome.
Dietary Baicalin Zinc Supplementation Alleviates Oxidative Stress and Enhances Nutrition Absorption in Deoxynivalenol Challenged Pigs.
Heme Oxygenase-1-Mediated Autophagy Protects against Oxidative Damage in Rat Nucleus Pulposus-Derived Mesenchymal Stem Cells.
Environmental Pollutant Benzo[a]pyrene Induces Recurrent Pregnancy Loss through Promoting Apoptosis and Suppressing Migration of Extravillous Trophoblast.
Disease Mutation Study Identifies Critical Residues for Phosphatidylserine Flippase ATP11A.
Rhein Suppresses Neuroinflammation via Multiple Signaling Pathways in LPS-Stimulated BV2 Microglia Cells.
Hydrogen Gas Attenuates Hypoxic-Ischemic Brain Injury via Regulation of the MAPK/HO-1/PGC-1a Pathway in Neonatal Rats.
Human Tissue Kallikrein 1 Improves Erectile Dysfunction of Streptozotocin-Induced Diabetic Rats by Inhibition of Excessive Oxidative Stress and Activation of the PI3K/AKT/eNOS Pathway.
Bergenin Attenuates Hepatic Fibrosis by Regulating Autophagy Mediated by the PPAR-γ/TGF-β Pathway.
Hyperglycemia Induces Endoplasmic Reticulum Stress in Atrial Cardiomyocytes, and Mitofusin-2 Downregulation Prevents Mitochondrial Dysfunction and Subsequent Cell Death.
Mild Hypothermia Attenuates Hepatic Ischemia-Reperfusion Injury through Regulating the JAK2/STAT3-CPT1a-Dependent Fatty Acid β-Oxidation.
Dexmedetomidine Attenuates Neurotoxicity in Developing Rats Induced by Sevoflurane through Upregulating BDNF-TrkB-CREB and Downregulating ProBDNF-P75NRT-RhoA Signaling Pathway.
NLRC3 Delays the Progression of AD in APP/PS1 Mice via Inhibiting PI3K Activation.
Qingjie Fuzheng Granule Inhibited the Migration and Invasion of Colorectal Cancer Cells by Regulating the lncRNA ANRIL/let-7a/TGF-β1/Smad Axis.
The Nrf2/PGC1α Pathway Regulates Antioxidant and Proteasomal Activity to Alter Cisplatin Sensitivity in Ovarian Cancer.
Congrong Shujing Granule-Induced GRP78 Expression Reduced Endoplasmic Reticulum Stress and Neuronal Apoptosis in the Midbrain in a Parkinson's Disease Rat Model.
LncRNA CAR10 Upregulates PDPK1 to Promote Cervical Cancer Development by Sponging miR-125b-5p.
Fasting Induces Hepatocellular Carcinoma Cell Apoptosis by Inhibiting SET8 Expression.
Tyrosine Kinase Receptors Axl and MerTK Mediate the Beneficial Effect of Electroacupuncture in a Cuprizone-Induced Demyelinating Model.
Gubenzhike Recipe Ameliorates Respiratory Mucosal Immunity in Mice with Chronic Obstructive Pulmonary Disease through Upregulation of the γδT Lymphocytes and KGF Levels.
Hypouricemic Effects of Extracts from Urtica hyperborea Jacq. ex Wedd. in Hyperuricemia Mice through XOD, URAT1, and OAT1.
Gentiopicroside Ameliorates Oxidative Stress and Lipid Accumulation through Nuclear Factor Erythroid 2-Related Factor 2 Activation.
N-Butanol Extract of Gastrodia elata Suppresses Inflammatory Responses in Lipopolysaccharide-Stimulated Macrophages and Complete Freund's Adjuvant- (CFA-) Induced Arthritis Rats via Inhibition of MAPK Signaling Pathway.
Effect of Thymoquinone on Acute Kidney Injury Induced by Sepsis in BALB/c Mice.
HuR Affects Proliferation and Apoptosis of Chronic Lymphocytic Leukemia Cells via NF-κB Pathway.
Azelaic Acid Exerts Antileukemia Effects against Acute Myeloid Leukemia by Regulating the Prdxs/ROS Signaling Pathway.
Melatonin Alleviates Neuroinflammation and Metabolic Disorder in DSS-Induced Depression Rats.
Suppression of NLRP3 Inflammasome, Pyroptosis, and Cell Death by NIM811 in Rotenone-Exposed Cells as an in vitro Model of Parkinson's Disease.
MiR-1307-5p targeting TRAF3 upregulates the MAPK/NF-κB pathway and promotes lung adenocarcinoma proliferation.
XIST lost induces ovarian cancer stem cells to acquire taxol resistance via a KMT2C-dependent way.
TET1 promotes fatty acid oxidation and inhibits NAFLD progression by hydroxymethylation of PPARα promoter.
Integrin α1 promotes tumorigenicity and progressive capacity of colorectal cancer.
PFKP is transcriptionally repressed by BRCA1/ZBRK1 and predicts prognosis in breast cancer.
Structure-function analyses of candidate small molecule RPN13 inhibitors with antitumor properties.
Jia-Ji Electro-Acupuncture Improves Locomotor Function With Spinal Cord Injury by Regulation of Autophagy Flux and Inhibition of Necroptosis.
Hydrogen Sulfide Overproduction Is Involved in Acute Ischemic Cerebral Injury Under Hyperhomocysteinemia.
Olfactory Mucosa Mesenchymal Stem Cells Ameliorate Cerebral Ischemic/Reperfusion Injury Through Modulation of UBIAD1 Expression.
Differences in DNA Methylation Reprogramming Underlie the Sexual Dimorphism of Behavioral Disorder Caused by Prenatal Stress in Rats.
iTRAQ-Based Quantitative Proteomic Analysis of Intestines in Murine Polymicrobial Sepsis with Hydrogen Gas Treatment.
Identification of a Novel c-Myc Inhibitor 7594-0037 by Structure-Based Virtual Screening and Investigation of Its Anti-Cancer Effect on Multiple Myeloma.
The Potential Effects of Aliskiren on Atrial Remodeling Induced by Chronic Intermittent Hypoxia in Rats.
Electro-Acupuncture Promotes the Differentiation of Endogenous Neural Stem Cells via Exosomal microRNA 146b After Ischemic Stroke.
Paeoniflorin Ameliorates Chronic Hypoxia/SU5416-Induced Pulmonary Arterial Hypertension by Inhibiting Endothelial-to-Mesenchymal Transition.
The knockdown of the sepiapterin reductase gene suppresses the proliferation of breast cancer by inducing ROS-mediated apoptosis.
Chaetomugilin J Enhances Apoptosis in Human Ovarian Cancer A2780 Cells Induced by Cisplatin Through Inhibiting Pink1/Parkin Mediated Mitophagy.
MicroRNA-623 Inhibits Epithelial-Mesenchymal Transition to Attenuate Glioma Proliferation by Targeting TRIM44.
Excessive Treadmill Training Enhances Brain-Specific MicroRNA-34a in the Mouse Hippocampus.
Chronic Intermittent Hypobaric Hypoxia Restores Hippocampus Function and Rescues Cognitive Impairments in Chronic Epileptic Rats via Wnt/β-catenin Signaling.
β-Elemene Enhances the Chemotherapeutic Effect of 5-Fluorouracil in Triple-Negative Breast Cancer via PI3K/AKT, RAF-MEK-ErK, and NF-κB Signaling Pathways.
Elevated Levels of circRUNX1 in Colorectal Cancer Promote Cell Growth and Metastasis via miR-145-5p/IGF1 Signalling.
Microsatellite Instability-Related ACVR2A Mutations Partially Account for Decreased Lymph Node Metastasis in MSI-H Gastric Cancers.
Long Noncoding RNA NEAT1 Upregulates Survivin and Facilitates Gallbladder Cancer Progression by Sponging microRNA-335.
Alpha1-Antitrypsin in Urinary Extracellular Vesicles: A Potential Biomarker of Diabetic Kidney Disease Prior to Microalbuminuria.
Empagliflozin Protects Against Proximal Renal Tubular Cell Injury Induced by High Glucose via Regulation of Hypoxia-Inducible Factor 1-Alpha.
Simultaneous Inhibition of Ornithine Decarboxylase 1 and Pyruvate Kinase M2 Exerts Synergistic Effects Against Hepatocellular Carcinoma Cells.
MiR-935/HIF1α Feedback Loop Inhibits the Proliferation and Invasiveness of Glioma.
SNHG9 was upregulated in NSCLC and associated with DDP-resistance and poor prognosis of NSCLC patients.
Brequinar inhibits enterovirus replication by targeting biosynthesis pathway of pyrimidines.
A New Rat Model of Chronic Cerebral Hypoperfusion Resulting in Early-Stage Vascular Cognitive Impairment.
Overexpression of IGFBP5 Enhances Radiosensitivity Through PI3K-AKT Pathway in Prostate Cancer.
Long Noncoding RNA LINC00261 Reduces Proliferation and Migration of Breast Cancer Cells via the NME1-EMT Pathway.
Resatorvid Relieves Breast Cancer Complicated with Depression by Inactivating Hippocampal Microglia Through TLR4/NF-κB/NLRP3 Signaling Pathway.
The lncRNA BCYRN1 Functions as an Oncogene in Human Glioma by Downregulating miR-125a-5p in vitro.
Pyruvate dehydrogenase kinase 1 interferes with glucose metabolism reprogramming and mitochondrial quality control to aggravate stress damage in cancer.
Long Noncoding RNA DSCAM-AS1 Facilitates Colorectal Cancer Cell Proliferation and Migration via miR-137/Notch1 Axis.
Arsenic trioxide (ATO) induced degradation of Cyclin D1 sensitized PD-1/PD-L1 checkpoint inhibitor in oral and esophageal squamous cell carcinoma.
Translocator Protein 18 kDa (TSPO) Deficiency Inhibits Microglial Activation and Impairs Mitochondrial Function.
Mitochondrial Iron Overload-Mediated Inhibition of Nrf2-HO-1/GPX4 Assisted ALI-Induced Nephrotoxicity.
Histone Deacetylase SIRT1 Mediates C5b-9-Induced Cell Cycle in Oligodendrocytes.
Oleoylethanolamide Protects Against Acute Liver Injury by Regulating Nrf-2/HO-1 and NLRP3 Pathways in Mice.
A Mechanism of Action Study on Danggui Sini Decoction to Discover Its Therapeutic Effect on Gastric Cancer.
JAK2V617F Mutation Promoted IL-6 Production and Glycolysis via Mediating PKM1 Stabilization in Macrophages.
Bu-Shen-Huo-Xue Decoction Ameliorates Diabetic Nephropathy by Inhibiting Rac1/PAK1/p38MAPK Signaling Pathway in High-Fat Diet/Streptozotocin-Induced Diabetic Mice.
miR-222 Suppresses Immature Porcine Sertoli Cell Growth by Targeting the GRB10 Gene Through Inactivating the PI3K/AKT Signaling Pathway.
Bu-Yin-Qian-Zheng Formula Ameliorates MPP+-Induced Mitochondrial Dysfunction in Parkinson's Disease via Parkin.
Molecular and Immune Characteristics for Lung Adenocarcinoma Patients With ERLIN2 Overexpression.
microRNA-630 Regulates Underglycosylated IgA1 Production in the Tonsils by Targeting TLR4 in IgA Nephropathy.
Metabolomics Deciphers Potential Targets of Xuefu Zhuyu Decoction Against Traumatic Brain Injury in Rat.
Susceptibility to Hyperglycemia in Rats With Stress-Induced Depressive-Like Behavior: Involvement of IL-6 Mediated Glucose Homeostasis Signaling.
PKM2-c-Myc-Survivin Cascade Regulates the Cell Proliferation, Migration, and Tamoxifen Resistance in Breast Cancer.
Effects of Xiaoyaosan on Depressive-Like Behaviors in Rats With Chronic Unpredictable Mild Stress Through HPA Axis Induced Astrocytic Activities.
Lian Hua Qing Wen Capsules, a Potent Epithelial Protector in Acute Lung Injury Model, Block Proapoptotic Communication Between Macrophages, and Alveolar Epithelial Cells.
ARP-1 Regulates the Transcriptional Activity of the Aromatase Gene in the Mouse Brain.
Scutellarein inhibits BLM-mediated pulmonary fibrosis by affecting fibroblast differentiation, proliferation, and apoptosis.
MicroRNA-34a Inhibition Alleviates Lung Injury in Cecal Ligation and Puncture Induced Septic Mice.
PPARγ as an E3 Ubiquitin-Ligase Impedes Phosphate-Stat6 Stability and Promotes Prostaglandins E2-Mediated Inhibition of IgE Production in Asthma.
Schisandrin B Inhibits Osteoclastogenesis and Protects Against Ovariectomy-Induced Bone Loss.
Toddalolactone Protects Lipopolysaccharide-Induced Sepsis and Attenuates Lipopolysaccharide-Induced Inflammatory Response by Modulating HMGB1-NF-κB Translocation.
MiR-10a-5p-Mediated Syndecan 1 Suppression Restricts Porcine Hemagglutinating Encephalomyelitis Virus Replication.
Eye Drops of Metformin Prevents Fibrosis After Glaucoma Filtration Surgery in Rats via Activating AMPK/Nrf2 Signaling Pathway.
CoenzymeQ10-Induced Activation of AMPK-YAP-OPA1 Pathway Alleviates Atherosclerosis by Improving Mitochondrial Function, Inhibiting Oxidative Stress and Promoting Energy Metabolism.
A miR-146a-5p/TRAF6/NF-kB p65 axis regulates pancreatic cancer chemoresistance: functional validation and clinical significance.
α1,6-Fucosyltransferase (FUT8) regulates the cancer-promoting capacity of cancer-associated fibroblasts (CAFs) by modifying EGFR core fucosylation (CF) in non-small cell lung cancer (NSCLC).
Cardio-renal Exosomes in Myocardial Infarction Serum Regulate Proangiogenic Paracrine Signaling in Adipose Mesenchymal Stem Cells.
Theta-burst transcranial magnetic stimulation promotes stroke recovery by vascular protection and neovascularization.
Graphene oxide improves postoperative cognitive dysfunction by maximally alleviating amyloid beta burden in mice.
Targeting BCL10 by small peptides for the treatment of B cell lymphoma.
Flubendazole elicits anti-cancer effects via targeting EVA1A-modulated autophagy and apoptosis in Triple-negative Breast Cancer.
Protein acetylation derepresses Serotonin Synthesis to potentiate Pancreatic Beta-Cell Function through HDAC1-PKA-Tph1 signaling.
Homozygous MESP1 knock-in reporter hESCs facilitated cardiovascular cell differentiation and myocardial infarction repair.
Extracellular vesicle-mediated delivery of miR-101 inhibits lung metastasis in osteosarcoma.
Aberrant miR-1246 expression promotes radioresistance in non-small cell lung cancer: a potential prognostic biomarker and radiotherapy sensitization target.
KLF13 suppresses the proliferation and growth of colorectal cancer cells through transcriptionally inhibiting HMGCS1-mediated cholesterol biosynthesis.
TIPE Regulates DcR3 Expression and Function by Activating the PI3K/AKT Signaling Pathway in CRC.
Forkhead Box Q1 Is Critical to Angiogenesis and Macrophage Recruitment of Colorectal Cancer.
Up-regulation of L Antigen Family Member 3 Associates With Aggressive Progression of Breast Cancer.
A Natural Dietary Flavone Myricetin as an α-Hemolysin Inhibitor for Controlling Staphylococcus aureus Infection.
Steroid 5α-Reductase Type I Induces Cell Viability and Migration via Nuclear Factor-κB/Vascular Endothelial Growth Factor Signaling Pathway in Colorectal Cancer.
The SIRT6-Autophagy-Warburg Effect Axis in Papillary Thyroid Cancer.
Methylation-Induced Silencing of ALDH2 Facilitates Lung Adenocarcinoma Bone Metastasis by Activating the MAPK Pathway.
Prognostic and Clinicopathological Significance of X-Box-Binding Protein 1 and N-Acetyltransferase 1 in Gallbladder Cancer.
NLRP6 contributes to inflammation and brain injury following intracerebral haemorrhage by activating autophagy.
Low-dose naltrexone inhibits the epithelial-mesenchymal transition of cervical cancer cells in vitro and effects indirectly on tumor-associated macrophages in vivo.
Increased regulatory T cells and eosinophils characterize atopic dermatitis-like graft-versus-host disease compared with lichen planus-like graft-versus-host disease.
Sublethal Levels of Antibiotics Promote Bacterial Persistence in Epithelial Cells.
Mitochondrial Transplantation Attenuates Brain Dysfunction in Sepsis by Driving Microglial M2 Polarization.
S-palmitoylation of swine interferon-inducible transmembrane protein is essential for its anti-JEV activity.
Deficiency of Grx1 leads to high sensitivity of HeLaS3 cells to oxidative stress via excessive accumulation of intracellular oxidants including ROS.
Estrogen Exerts Neuroprotective Effects in Vascular Dementia Rats by Suppressing Autophagy and Activating the Wnt/β-Catenin Signaling Pathway.
MCC950 Inhibits NLRP3 Inflammasome and Alleviates Axonal Injures in Early Stages of Diffuse Axonal Injury in Rats.
A novel GNAS-mutated human induced pluripotent stem cell model for understanding GNAS-mutated tumors.
Visualization of translocator protein (18 kDa) (TSPO) in the retina of diabetic retinopathy rats using fluorine-18-DPA-714.
SRSF10 inhibits the polymerase activity and replication of avian influenza virus by regulating the alternative splicing of chicken ANP32A.
The deubiquitylase USP2 maintains ErbB2 abundance via counteracting endocytic degradation and represents a therapeutic target in ErbB2-positive breast cancer.
RUNX3-dependent oxidative epithelial-to-mesenchymal transition in methamphetamine-induced chronic lung injury.
ACE2 modulates glucose homeostasis through GABA signaling during metabolic stress.
Musashi2 promotes the progression of pancreatic cancer through a novel ISYNA1-p21/ZEB-1 pathway.
Tacrolimus ameliorates tubulointerstitial inflammation in diabetic nephropathy via inhibiting the NFATc1/TRPC6 pathway.
Knockdown of endogenous RNF4 exacerbates ischaemia-induced cardiomyocyte apoptosis in mice.
Rosamultin Attenuates Acute Hypobaric Hypoxia-Induced Bone Injuries by Regulation of Sclerostin and Its Downstream Signals.
Polyphyllin II inhibits human bladder cancer migration and invasion by regulating EMT-associated factors and MMPs.
Sirtuin 3-mediated deacetylation of acyl-CoA synthetase family member 3 by protocatechuic acid attenuates non-alcoholic fatty liver disease.
Methamphetamine induces GSDME-dependent cell death in hippocampal neuronal cells through the endoplasmic reticulum stress pathway.
Inhibition of NK1R attenuates LPS-induced microglial inflammation and consequent death of PC12 cells.
NS5-V372A and NS5-H386Y variations are responsible for differences in interferon α/β induction and co-contribute to the replication advantage of Japanese encephalitis virus genotype I over genotype III in ducklings.
H63D variant of the homeostatic iron regulator (HFE) gene alters α-synuclein expression, aggregation, and toxicity.
Interleukin-18 levels in the hippocampus and behavior of adult rat offspring exposed to prenatal restraint stress during early and late pregnancy.
Control the fate of human umbilical cord mesenchymal stem cells with dual-enzymatically cross-linked gelatin hydrogels for potential applications in nerve regeneration.
Duck IFIT5 differentially regulates Tembusu virus replication and inhibits virus-triggered innate immune response.
The effect of monotropein on alleviating cisplatin-induced acute kidney injury by inhibiting oxidative damage, inflammation and apoptosis.
Dual PI3K/mTOR inhibitor PKI-402 suppresses the growth of ovarian cancer cells by degradation of Mcl-1 through autophagy.
SOCS3-deficient lung epithelial cells uptaking neutrophil-derived SOCS3 worsens lung influenza infection.
The roles of grouper TANK in innate immune defense against iridovirus and nodavirus infections.
Zinc exerts its renal protection effect on arsenic-exposed common carp: A signaling network comprising Nrf2, NF-κB and MAPK pathways.
S-allyl-L-cysteine protects hepatocytes from indomethacin-induced apoptosis by attenuating endoplasmic reticulum stress.
HEATR1 promotes proliferation in gastric cancer in vitro and in vivo.
Autocrine INSL5 promotes tumor progression and glycolysis via activation of STAT5 signaling.
Circular RNA circREPS2 Acts as a Sponge of miR-558 to Suppress Gastric Cancer Progression by Regulating RUNX3/β-catenin Signaling.
The microRNA/TET3/REST axis is required for olfactory globose basal cell proliferation and male behavior.
Oxidative stress mediates the apoptosis and epigenetic modification of the Bcl-2 promoter via DNMT1 in a cigarette smoke-induced emphysema model.
Myricanol 5-fluorobenzyloxy ether regulation of survivin pathway inhibits human lung adenocarcinoma A549 cells growth in vitro.
Characterization of Low Molecular Weight Sulfate Ulva Polysaccharide and its Protective Effect against IBD in Mice.
NOD2/c-Jun NH2-Terminal Kinase Triggers Mycoplasma ovipneumoniae-Induced Macrophage Autophagy.
L-Theanine affects intestinal mucosal immunity by regulating short-chain fatty acid metabolism under dietary fiber feeding.
Astaxanthin attenuates oxidative stress and immune impairment in D-galactose-induced aging in rats by activating the Nrf2/Keap1 pathway and suppressing the NF-κB pathway.
Neural progenitor cell pyroptosis contributes to Zika virus-induced brain atrophy and represents a therapeutic target.
(+)-Clausenamide protects against drug-induced liver injury by inhibiting hepatocyte ferroptosis.
Overexpression of MicroRNA-9a-5p Ameliorates NLRP1 Inflammasome-mediated Ischemic Injury in Rats Following Ischemic Stroke.
Inhibition of autophagy enhances timosaponin AIII-induced lung cancer cell apoptosis and anti-tumor effect in vitro and in vivo.
Inflammasome/NF-κB translocation inhibition via PPARγ agonist mitigates inorganic mercury induced nephrotoxicity.
FUT9-Driven Programming of Colon Cancer Cells towards a Stem Cell-Like State.
Adenovirus-mediated specific tumor tagging facilitates CAR-T therapy against antigen-mismatched solid tumors.
The AKT/GSK3-Mediated Slug Expression Contributes to Oxaliplatin Resistance in Colorectal Cancer via Upregulation of ERCC1.
Combination of luteolin and lycopene effectively protect against the "two-hit" in NAFLD through Sirt1/AMPK signal pathway.
Four active monomers from Moutan Cortex exert inhibitory effects against oxidative stress by activating Nrf2/Keap1 signaling pathway.
Herpes Simplex Virus Type 2 Inhibits Type I IFN Signaling Mediated by the Novel E3 Ubiquitin Protein Ligase Activity of Viral Protein ICP22.
Targeting SLC7A11 specifically suppresses the progression of colorectal cancer stem cells via inducing ferroptosis.
Expression Level of Small Envelope Protein in Addition to Sequence Divergence inside Its Major Hydrophilic Region Contributes to More Efficient Surface Antigen Secretion by Hepatitis B Virus Subgenotype D2 than Subgenotype A2.
Down-regulation of NTSR3 inhibits cell growth and metastasis, as well as the PI3K-AKT and MAPK signaling pathways in colorectal cancer.
Cytotoxic effects of vitamins K1, K2, and K3 against human T lymphoblastoid leukemia cells through apoptosis induction and cell cycle arrest.
Ubiquitin specific protease 5 negatively regulates the IFNs-mediated antiviral activity via targeting SMURF1.
Lycopene protects neuroblastoma cells against oxidative damage via depression of ER stress.
Upregulation of secreted phosphoprotein 1 affects malignant progression, prognosis, and resistance to cetuximab via the KRAS/MEK pathway in head and neck cancer.
Resveratrol modulates the apoptosis and autophagic death of human lung adenocarcinoma A549 cells via a p53‑dependent pathway: Integrated bioinformatics analysis and experimental validation.
Schisandrin A restrains osteoclastogenesis by inhibiting reactive oxygen species and activating Nrf2 signalling.
YY1-mediated PTEN dephosphorylation antagonizes IR-induced DNA repair contributing to tongue squamous cell carcinoma radiosensitization.
Spatiotemporal expression of neurogenic locus notch homolog protein 1 in developing caudal spinal cord of fetuses with anorectal malformations from ETU-fed rats.
Silica nanoparticles induce spermatogenesis disorders via L3MBTL2-DNA damage-p53 apoptosis and RNF8-ubH2A/ubH2B pathway in mice.
Autophagy plays a protective role during Pseudomonas aeruginosa-induced apoptosis via ROS-MAPK pathway.
LKB1-MARK2 signalling mediates lipopolysaccharide-induced production of cytokines in mouse macrophages.
Dihydrotanshinone I inhibits ovarian cancer cell proliferation and migration by transcriptional repression of PIK3CA gene.
KIAA1429 regulates cell proliferation by targeting c-Jun messenger RNA directly in gastric cancer.
Silencing long non‑coding RNA NEAT1 suppresses the tumorigenesis of infantile hemangioma by competitively binding miR‑33a‑5p to stimulate HIF1α/NF‑κB pathway.
Arsenic (III) and/or copper (II) induces oxidative stress in chicken brain and subsequent effects on mitochondrial homeostasis and autophagy.
Dihydrotanshinone I inhibits human glioma cell proliferation via the activation of ferroptosis.
Essential roles of S100A10 in Toll-like receptor signaling and immunity to infection.
miR-103a-3p regulates mitophagy in Parkinson's disease through Parkin/Ambra1 signaling.
p53 promotes ZDHHC1-mediated IFITM3 palmitoylation to inhibit Japanese encephalitis virus replication.
A Histomorphological Study of the Divergent Corpus Spongiosum Surrounding the Urethral Plate in Hypospadias.
Exosomal miR-1255b-5p targets human telomerase reverse transcriptase in colorectal cancer cells to suppress epithelial-to-mesenchymal transition.
Polydatin alleviates parkinsonism in MPTP-model mice by enhancing glycolysis in dopaminergic neurons.
Proteomic analyses reveal that Orf virus induces the activation and maturation of mouse bone marrow-derived dendritic cells.
Biomechanically reduced expression of Derlin-3 is linked to the apoptosis of chondrocytes in the mandibular condylar cartilage via the endoplasmic reticulum stress pathway.
T-type calcium channel blockade induces apoptosis in C2C12 myotubes and skeletal muscle via endoplasmic reticulum stress activation.
Impaired NLRP3 inflammasome activation/pyroptosis leads to robust inflammatory cell death via caspase-8/RIPK3 during coronavirus infection.
Calreticulin promotes EMT in pancreatic cancer via mediating Ca2+ dependent acute and chronic endoplasmic reticulum stress.
Profiling pro-neural to mesenchymal transition identifies a lncRNA signature in glioma.
Revealing active ingredients, potential targets, and action mechanism of Ermiao fang for treating endometritis based on network pharmacology strategy.
c-Myc inactivation of p53 through the pan-cancer lncRNA MILIP drives cancer pathogenesis.
Defect of SLC38A3 promotes epithelial-mesenchymal transition and predicts poor prognosis in esophageal squamous cell carcinoma.
Transcriptomic and Proteomic Analysis Reveals Mechanisms of Patulin-Induced Cell Toxicity in Human Embryonic Kidney Cells.
Anticancer Effects of Honokiol via Mitochondrial Dysfunction Are Strongly Enhanced by the Mitochondria-Targeting Carrier Berberine.
Rosmarinic Acid Alleviates Inflammation, Apoptosis, and Oxidative Stress through Regulating miR-155-5p in a Mice Model of Parkinson's Disease.
miR-497 regulates fatty acid synthesis via LATS2 in bovine mammary epithelial cells.
Amorphous silica nanoparticles accelerated atherosclerotic lesion progression in ApoE-/- mice through endoplasmic reticulum stress-mediated CD36 up-regulation in macrophage.
Sodium butyrate promotes milk fat synthesis in bovine mammary epithelial cells via GPR41 and its downstream signalling pathways.
Designing an eEF2K-Targeting PROTAC small molecule that induces apoptosis in MDA-MB-231 cells.
Sestrin2 promotes angiogenesis to alleviate brain injury by activating Nrf2 through regulating the interaction between p62 and Keap1 following photothrombotic stroke in rats.
Upregulation of Glutaredoxin 2 alleviates oxygen-glucose deprivation/reoxygenation-induced apoptosis and ROS production in neurons by enhancing Nrf2 signaling via modulation of GSK-3β.
A novel bile acid analog, A17, ameliorated non-alcoholic steatohepatitis in high-fat diet-fed hamsters.
Polydatin executes anticancer effects against glioblastoma multiforme by inhibiting the EGFR-AKT/ERK1/2/STAT3-SOX2/Snail signaling pathway.
Notch1 contributes to TNF-α-induced proliferation and migration of airway smooth muscle cells through regulation of the Hes1/PTEN axis.
Knockdown of fatty acid binding protein 4 exacerbates Bacillus Calmette-Guerin infection-induced RAW264.7 cell apoptosis via the endoplasmic reticulum stress pathway.
Enhanced therapeutic efficacy of a novel colon-specific nanosystem loading emodin on DSS-induced experimental colitis.
CaMKII as a key regulator of contrast-induced nephropathy through mPTP opening in HK-2 cells.
Histone demethylase Jmjd3 modulates osteoblast apoptosis induced by tumor necrosis factor-alpha through directly targeting RASSF5.
RNA binding motif protein 10 suppresses lung cancer progression by controlling alternative splicing of eukaryotic translation initiation factor 4H.
Spatiotemporal heterogeneity of PPARγ expression in porcine uteroplacenta for regulating of placental angiogenesis through VEGF-mediated signalling.
Identification of octopus peptide and its promotion of β-casein synthesis in a mouse mammary epithelial cell line.
Low-intensity pulsed ultrasound protects subchondral bone in rabbit temporomandibular joint osteoarthritis by suppressing TGF-β1/Smad3 pathway.
Involvement of NMDAR/PSD-95/nNOS-NO-cGMP pathway in embryonic exposure to BPA induced learning and memory dysfunction of rats.
Long noncoding RNA LINC00346 promotes glioma cell migration, invasion and proliferation by up-regulating ROCK1.
MicroRNA-127-5p impairs function of granulosa cells via HMGB2 gene in premature ovarian insufficiency.
Oxidative stress is important in the pathogenesis of stress-related mucosal disease.
Brilliant blue G attenuates neuro-inflammation via regulating MAPKs and NF-κB signaling pathways in lipopolysaccharide-induced BV2 microglia cells.
Methylprednisolone potentiates tetrandrine pharmacodynamics against human T lymphoblastoid leukemia MOLT-4 cells via regulation of NF-κB activation and cell cycle transition.
Activation of angiotensin II type-2 receptor protects against cigarette smoke-induced COPD.
Up-regulation of astrocyte excitatory amino acid transporter 2 alleviates central sensitization in a rat model of chronic migraine.
TRIM25 upregulation by Mycobacterium tuberculosis infection promotes intracellular survival of M.tb in RAW264.7 cells.
Indirubin alleviates bleomycin-induced pulmonary fibrosis in mice by suppressing fibroblast to myofibroblast differentiation.
Nucleoredoxin interaction with flightless-I/actin complex is differentially altered in alcoholic liver disease.
Mycoplasma bovis-generated reactive oxygen species and induced apoptosis in bovine mammary epithelial cell cultures.
Sox13 promotes hepatocellular carcinoma metastasis by transcriptionally activating Twist1.
TMEM176A acts as a tumor suppressor gene in pancreatic cancer by inhibiting ERK signaling.
Deficiency of microglial Hv1 channel is associated with activation of autophagic pathway and ROS production in LPC-induced demyelination mouse model.
Effects of Osthole on Progesterone Secretion in Chicken Preovulatory Follicles Granulosa Cells.
Amino acid transporter LAT1 in tumor-associated vascular endothelium promotes angiogenesis by regulating cell proliferation and VEGF-A-dependent mTORC1 activation.
Anthocyanins decrease the internalization of TiO2 nanoparticles into 3D Caco-2 spheroids.
Hypoxia induces sorafenib resistance mediated by autophagy via activating FOXO3a in hepatocellular carcinoma.
Effective RNA Knockdown Using CRISPR-Cas13a and Molecular Targeting of the EML4-ALK Transcript in H3122 Lung Cancer Cells.
MiR-103a-3p promotes tumour glycolysis in colorectal cancer via hippo/YAP1/HIF1A axis.
Velvet antler polypeptide prevents the disruption of hepatic tight junctions via inhibiting oxidative stress in cholestatic mice and liver cell lines.
Identification of Milk Fat Metabolism-Related Pathways of the Bovine Mammary Gland during Mid and Late Lactation and Functional Verification of the ACSL4 Gene.
Eurocristatine, a plant alkaloid from Eurotium cristatum, alleviates insulin resistance in db/db diabetic mice via activation of PI3K/AKT signaling pathway.
Baicalein ameliorates ionizing radiation-induced injuries by rebalancing gut microbiota and inhibiting apoptosis.
A novel polysaccharide from Acorus tatarinowii protects against LPS-induced neuroinflammation and neurotoxicity by inhibiting TLR4-mediated MyD88/NF-κB and PI3K/Akt signaling pathways.
Binding properties of marine bromophenols with human protein tyrosine phosphatase 1B: Molecular docking, surface plasmon resonance and cellular insulin resistance study.
Targeting HMGB3/hTERT axis for radioresistance in cervical cancer.
Synergism of TNF-α and IFN-γ triggers inflammatory cell death, tissue damage, and mortality in SARS-CoV-2 infection and cytokine shock syndromes.
Duck enteritis virus pUL47, as a late structural protein localized in the nucleus, mainly depends on residues 40 to 50 and 768 to 777 and inhibits IFN-β signalling by interacting with STAT1.
Immunoproteasome is up-regulated in rotenone-induced Parkinson's disease rat model.
Berberine inhibits proliferation and induces G0/G1 phase arrest in colorectal cancer cells by downregulating IGF2BP3.
iTRAQ-based quantitative proteomic analysis of the therapeutic effects of 2% hydrogen gas inhalation on brain injury in septic mice.
Combination of N, N'-dicyclohexyl-N-arachidonic acylurea and tacrolimus prolongs cardiac allograft survival in mice.
Long non-coding RNA OIP5-AS1 promotes pancreatic cancer cell growth through sponging miR-342-3p via AKT/ERK signaling pathway.
Role of fucosyltransferase IV in the migration and invasion of human melanoma cells.
OGDHL silencing promotes hepatocellular carcinoma by reprogramming glutamine metabolism.
miR-142-5P regulates triglyceride by targeting CTNNB1 in goat mammary epithelial cells.
Transcriptome sequencing analysis of mono‑ADP‑ribosylation in colorectal cancer cells.
Annexin-1 Mimetic Peptide Ac2-26 Suppresses Inflammatory Mediators in LPS-Induced Astrocytes and Ameliorates Pain Hypersensitivity in a Rat Model of Inflammatory Pain.
Mitochondrial dysfunction is involved in aristolochic acid I-induced apoptosis in renal proximal tubular epithelial cells.
Exogenous spermine attenuates rat diabetic cardiomyopathy via suppressing ROS-p53 mediated downregulation of calcium-sensitive receptor.
Programmable prodrug micelle with size-shrinkage and charge-reversal for chemotherapy-improved IDO immunotherapy.
PM2.5 in poultry houses synergizes with Pseudomonas aeruginosa to aggravate lung inflammation in mice through the NF-κB pathway.
Shear stress stimulates integrin β1 trafficking and increases directional migration of cancer cells via promoting deacetylation of microtubules.
TOPORS, a tumor suppressor protein, contributes to the maintenance of higher-order chromatin architecture.
Protective effect of cilastatin against diclofenac-induced nephrotoxicity through interaction with diclofenac acyl glucuronide via organic anion transporters.
Palmatine induces G2/M phase arrest and mitochondrial-associated pathway apoptosis in colon cancer cells by targeting AURKA.
Protective effect of ginsenoside Rg5 against kidney injury via inhibition of NLRP3 inflammasome activation and the MAPK signaling pathway in high-fat diet/streptozotocin-induced diabetic mice.
Elevated SRC3 expression predicts pemetrexed resistance in lung adenocarcinoma.
LncRNA MFI2-AS1 promotes HCC progression and metastasis by acting as a competing endogenous RNA of miR-134 to upregulate FOXM1 expression.
Protein kinase CK2 participates in estrogen-mediated endothelial progenitor cell homing to endometriotic lesions through stromal cells in a stromal cell-derived factor-1- CXCR4-dependent manner.
BMP8A promotes survival and drug resistance via Nrf2/TRIM24 signaling pathway in clear cell renal cell carcinoma.
Mitochondria-related miR-574 reduces sperm ATP by targeting ND5 in aging males.
Rare Neurologic Disease-Associated Mutations of AIMP1 are Related with Inhibitory Neuronal Differentiation Which is Reversed by Ibuprofen.
Artesunate attenuates 2, 4-dinitrochlorobenzene-induced atopic dermatitis by down-regulating Th17 cell responses in BALB/c mice.
Effect of miR-195-5p on cardiomyocyte apoptosis in rats with heart failure by regulating TGF-β1/Smad3 signaling pathway.
TET2-mediated Cdkn2A DNA hydroxymethylation in midbrain dopaminergic neuron injury of Parkinson's disease.
The Lumiptosome, an engineered luminescent form of the apoptosome can report cell death by using the same Apaf-1 dependent pathway.
P-21-activated kinase 1 contributes to tumor angiogenesis upon photodynamic therapy via the HIF-1α/VEGF pathway.
Neddylation-mediated Nedd4-2 activation regulates ubiquitination modification of renal NBCe1.
Concentration and Duration of Indoxyl Sulfate Exposure Affects Osteoclastogenesis by Regulating NFATc1 via Aryl Hydrocarbon Receptor.
Androgen aggravates liver fibrosis by activation of NLRP3 inflammasome in CCl4-induced liver injury mouse model.
In vitro and in vivo anti-Listeria effect of Succinoglycan Riclin through regulating MAPK/IL-6 axis and metabolic profiling.
Blueberry Prevents the Bladder Dysfunction in Bladder Outlet Obstruction Rats by Attenuating Oxidative Stress and Suppressing Bladder Remodeling.
Suppression of experimental atrial fibrillation in a canine model of rapid atrial pacing by the phosphodiesterase 3 inhibitor cilostazol.
Ketamine attenuates high-glucose-mediated endothelial inflammation in human umbilical vein endothelial cells.
Interleukin-4 Restores Insulin Sensitivity in Insulin-Resistant Osteoblasts by Increasing the Expression of Insulin Receptor Substrate 1.
NLRP6 expressed in astrocytes aggravates neurons injury after OGD/R through activating the inflammasome and inducing pyroptosis.
Dihydroartemisinin inhibits the proliferation of IgAN mesangial cells through the mTOR signaling pathway.
JTE-013 supplementation improves erectile dysfunction in rats with streptozotocin-induced type Ⅰ diabetes through the inhibition of the rho-kinase pathway, fibrosis, and apoptosis.
Danshen formula granule and salvianic acid A alleviate ethanol-induced neurotoxicity.
Resveratrol protects the integrity of alveolar epithelial barrier via SIRT1/PTEN/p-Akt pathway in methamphetamine-induced chronic lung injury.
Integrin β3 Modulates TLR4-Mediated Inflammation by Regulation of CD14 Expression in Macrophages in Septic Condition.
Inhibitory mechanism of muscone in liver cancer involves the induction of apoptosis and autophagy.
Samarium enriches antitumor activity of ZnO nanoparticles via downregulation of CXCR4 receptor and cytochrome P450.
Cyclovirobuxine D Exerts Anticancer Effects by Suppressing the EGFR-FAK-AKT/ERK1/2-Slug Signaling Pathway in Human Hepatocellular Carcinoma.
Lysophosphatidic acid receptor 4 regulates osteogenic and adipogenic differentiation of progenitor cells via inactivation of RhoA/ROCK1/β-catenin signaling.
HUWE1 promotes EGFR ubiquitination and degradation to protect against renal tubulointerstitial fibrosis.
Molecular hydrogen regulates PTEN-AKT-mTOR signaling via ROS to alleviate peritoneal dialysis-related peritoneal fibrosis.
Recombinant Human Milk Fat Globule-Epidermal Growth Factor 8 Attenuates Microthrombosis after Subarachnoid Hemorrhage in Rats.
Blockade of HSP70 by VER-155008 synergistically enhances bortezomib-induced cytotoxicity in multiple myeloma.
The marine-derived furanone reduces intracellular lipid accumulation in vitro by targeting LXRα and PPARα.
Mechanism of the hypoxia inducible factor 1/hypoxic response element pathway in rat myocardial ischemia/diazoxide post‑conditioning.
Ginsenosides reduce body weight and ameliorate hepatic steatosis in high fat diet‑induced obese mice via endoplasmic reticulum stress and p‑STAT3/STAT3 signaling.
Cystatin C promotes cognitive dysfunction in rats with cerebral microbleeds by inhibiting the ERK/synapsin Ia/Ib pathway.
WHIMP links the actin nucleation machinery to Src-family kinase signaling during protrusion and motility.
LongShengZhi capsule inhibits doxorubicin-induced heart failure by anti-oxidative stress.
The mechanism of PDA/PEI/5-Fu coated esophageal stent material on inhibiting cancer associated pathological cells.
DJ-1 exerts anti-inflammatory effects and regulates NLRX1-TRAF6 via SHP-1 in stroke.
Transcription co-activator P300 activates Elk1-aPKC-ι signaling mediated epithelial-to-mesenchymal transition and malignancy in hepatocellular carcinoma.
Quantitative Mitochondrial Proteomics Reveals ANXA7 as a Crucial Factor in Mitophagy.
miR-17 regulates the proliferation and differentiation of retinal progenitor cells by targeting CHMP1A.
SIRT3 inhibits cardiac hypertrophy by regulating PARP-1 activity.
BCAP31, a cancer/testis antigen-like protein, can act as a probe for non-small-cell lung cancer metastasis.
(20S)G-Rh2 Inhibits NF-κB Regulated Epithelial-Mesenchymal Transition by Targeting Annexin A2.
5-HT1AR alleviates Aβ-induced cognitive decline and neuroinflammation through crosstalk with NF-κB pathway in mice.
The Agpat4/LPA axis in colorectal cancer cells regulates antitumor responses via p38/p65 signaling in macrophages.
LINC00978 promotes hepatocellular carcinoma carcinogenesis partly via activating the MAPK/ERK pathway.
Posttranslational lysine 2-hydroxyisobutyrylation of human sperm tail proteins affects motility.
Design, Synthesis, and Biological Evaluation of Imidazo[1,2-a]pyridine Derivatives as Novel PI3K/mTOR Dual Inhibitors.
Dendrobium officinale polysaccharides protected against ethanol-induced acute liver injury in vivo and in vitro via the TLR4/NF-κB signaling pathway.
Optimization of Experimental Variables Influencing Apoptosome Biosensor in HEK293T Cells.
Protective effects of panax notoginseng saponin on dextran sulfate sodium-induced colitis in rats through phosphoinositide-3-kinase protein kinase B signaling pathway inhibition.
Extrahepatic deficiency of transferrin receptor 2 is associated with increased erythropoiesis independent of iron overload.
Dual regulation of p53 by the ribosome maturation factor SBDS.
Regulation of the linear ubiquitination of STAT1 controls antiviral interferon signaling.
HNF-1a promotes pancreatic cancer growth and apoptosis resistance via its target gene PKLR.
Alarmin HMGB1 Plays a Detrimental Role in Hippocampal Dysfunction Caused by Hypoxia-Ischemia Insult in Neonatal Mice: Evidence from the Application of the HMGB1 Inhibitor Glycyrrhizin.
Identification of ALPPL2 as a Naive Pluripotent State-Specific Surface Protein Essential for Human Naive Pluripotency Regulation.
TXNIP deficiency mitigates podocyte apoptosis via restraining the activation of mTOR or p38 MAPK signaling in diabetic nephropathy.
Synergetic inhibition of daidzein and regular exercise on breast cancer in bearing-4T1 mice by regulating NK cells and apoptosis pathway.
Neuronal BIN1 Regulates Presynaptic Neurotransmitter Release and Memory Consolidation.
HIF2-Induced Long Noncoding RNA RAB11B-AS1 Promotes Hypoxia-Mediated Angiogenesis and Breast Cancer Metastasis.
Microcystins-LR induced apoptosis via S-nitrosylation of GAPDH in colorectal cancer cells.
Ferulic acid isolated from propolis inhibits porcine parvovirus replication potentially through Bid-mediate apoptosis.
Histone demethylase KDM4A regulates adipogenic and osteogenic differentiation via epigenetic regulation of C/EBPα and canonical Wnt signaling.
Reversing a model of Parkinson's disease with in situ converted nigral neurons.
MiR-153-3p induces immune dysregulation by inhibiting PELI1 expression in umbilical cord-derived mesenchymal stem cells in patients with systemic lupus erythematosus.
PAQR3 protects against oxygen-glucose deprivation/reperfusion-induced injury through the ERK signaling pathway in N2A cells.
Esculetin Ameliorates Lipopolysaccharide-Induced Acute Lung Injury in Mice Via Modulation of the AKT/ERK/NF-κB and RORγt/IL-17 Pathways.
Quercetin suppresses migration and invasion by targeting miR-146a/GATA6 axis in fibroblast-like synoviocytes of rheumatoid arthritis.
Inhibition of miR-574-5p suppresses cell growth and metastasis and enhances chemosensitivity by targeting RNA binding protein QKI in cervical cancer cells.
Human placenta derived mesenchymal stromal cells alleviate GVHD by promoting the generation of GSH and GST in PD-1+T cells.
Regulatory T cell is critical for interleukin-33-mediated neuroprotection against stroke.
SUMOylation of vascular endothelial growth factor receptor 2 inhibits the proliferation, migration, and angiogenesis signaling pathway in non-small cell lung cancer.
Tizoxanide mitigates inflammatory response in LPS-induced neuroinflammation in microglia via restraining p38/MAPK pathway.
Astrocyte elevated gene 1 (AEG-1) promotes anoikis resistance and metastasis by inducing autophagy in hepatocellular carcinoma.
Disregulation of Autophagy in the Transgenerational Cc2d1a Mouse Model of Autism.
The Activation of Heat-Shock Protein After Copper(II) and/or Arsenic(III)-Induced Imbalance of Homeostasis, Inflammatory Response in Chicken Rectum.
BRM-SWI/SNF chromatin remodeling complex enables functional telomeres by promoting co-expression of TRF2 and TRF1.
Sustained mitochondrial biogenesis is essential to maintain caloric restriction-induced beige adipocytes.
Tolfenamic acid inhibits GSK-3β and PP2A mediated tau hyperphosphorylation in Alzheimer's disease models.
Highly expressed STAT1 contributes to the suppression of stemness properties in human paclitaxel-resistant ovarian cancer cells.
Arsenic induces dysfunctional autophagy via dual regulation of mTOR pathway and Beclin1-Vps34/PI3K complex in MLTC-1 cells.
The GTPase Rab27b regulates the release, autophagic clearance, and toxicity of α-synuclein.
BDH2 triggers ROS-induced cell death and autophagy by promoting Nrf2 ubiquitination in gastric cancer.
Enterovirus A71 Oncolysis of Malignant Gliomas.
Cytoplasmic PCNA is located in the actin belt and involved in osteoclast differentiation.
MiR-377-3p inhibits atherosclerosis-associated vascular smooth muscle cell proliferation and migration via targeting neuropilin2.
Molecular mechanism of targeted inhibition of HMGA2 via miRNAlet-7a in proliferation and metastasis of laryngeal squamous cell carcinoma.
Opening large-conductance potassium channels selectively induced cell death of triple-negative breast cancer.
Enhanced autophagic retrograde axonal transport by dynein intermediate chain upregulation improves Aβ clearance and cognitive function in APP/PS1 double transgenic mice.
L-3-n-butylphthalide attenuates inflammation response and brain edema in rat intracerebral hemorrhage model.
A Gold(I) Complex Containing an Oleanolic Acid Derivative as a Potential Anti-Ovarian-Cancer Agent by Inhibiting TrxR and Activating ROS-Mediated ERS.
Excretory/secretory products of Angiostrongylus cantonensis fifth-stage larvae induce endoplasmic reticulum stress via the Sonic hedgehog pathway in mouse astrocytes.
Immune profiling reveals prognostic genes in high-grade serous ovarian cancer.
Neurotoxicity of aluminum oxide nanoparticles and their mechanistic role in dopaminergic neuron injury involving p53-related pathways.
Cerenkov luminescence imaging is an effective preclinical tool for assessing colorectal cancer PD-L1 levels in vivo.
Mechanism of Heshouwuyin inhibiting the Cyt c/Apaf-1/Caspase-9/Caspase-3 pathway in spermatogenic cell apoptosis.
Regulatory effects of Prohibitin 1 on proliferation and apoptosis of pulmonary arterial smooth muscle cells in monocrotaline-induced PAH rats.
Synergistic Effect of Benzethonium Chloride Combined with Endoxan against Hepatocellular Carcinoma in Rats through Targeting Apoptosis Signaling Pathway.
Fast and unbiased purification of RNA-protein complexes after UV cross-linking.
Daucosterol linolenate from Sweet Potato Suppresses MCF7-Xenograft-Tumor Growth through Regulating PI3K/AKT Pathway.
A novel homozygous nonsense ZP1 variant causes human female infertility associated with empty follicle syndrome (EFS).
Structural Basis of Human Helicase DDX21 in RNA Binding, Unwinding, and Antiviral Signal Activation.
A mitophagic response to iron overload-induced oxidative damage associated with the PINK1/Parkin pathway in pancreatic beta cells.
lncRNA LA16c‑313D11.11 modulates the development of endometrial cancer by binding to and inhibiting microRNA‑205‑5p function and indirectly increasing PTEN activity.
Matrix Metalloproteinase 11 as a Novel Tumor Promoter and Diagnostic and Prognostic Biomarker for Pancreatic Ductal Adenocarcinoma.
Characterization of red ginseng-drug interaction by CYP3A activity increased in high dose administration in mice.
HMGB1-induced aberrant autophagy contributes to insulin resistance in granulosa cells in PCOS.
miR-196b-5p controls adipocyte differentiation and lipogenesis through regulating mTORC1 and TGF-β signaling.
Presynaptic Caytaxin prevents apoptosis via deactivating DAPK1 in the acute phase of cerebral ischemic stroke.
miR-203a suppresses cell proliferation by targeting RING-finger protein 6 in colorectal cancer.
Stomatin-like protein-2 confers neuroprotection effect in oxygen-glucose deprivation/reoxygenation-injured neurons by regulating AMPK/Nrf2 signalling.
Protective effect of quercetin on rat testes against cadmium toxicity by alleviating oxidative stress and autophagy.
BMP7 is Downregulated in Lumbosacral Spinal Cord of Rat Embryos With Anorectal Malformation.
Targeted immunomodulation of inflammatory monocytes across the blood-brain barrier by curcumin-loaded nanoparticles delays the progression of experimental autoimmune encephalomyelitis.
AMPH1 functions as a tumour suppressor in ovarian cancer via the inactivation of PI3K/AKT pathway.
SIRT2 suppresses expression of inflammatory factors via Hsp90-glucocorticoid receptor signalling.
CUDC-907, a novel dual PI3K and HDAC inhibitor, in prostate cancer: Antitumour activity and molecular mechanism of action.
The effect of lncRNA-ARAP1-AS2/ARAP1 on high glucose-induced cytoskeleton rearrangement and epithelial-mesenchymal transition in human renal tubular epithelial cells.
Reversal of prolonged obesity-associated cerebrovascular dysfunction by inhibiting microglial Tak1.
LHPP inhibits hepatocellular carcinoma cell growth and metastasis.
Melatonin protects against chronic stress-induced oxidative meiotic defects in mice MII oocytes by regulating SIRT1.
Human alkaline ceramidase 2 promotes the growth, invasion, and migration of hepatocellular carcinoma cells via sphingomyelin phosphodiesterase acid-like 3B.
Bisdemethoxycurcumin inhibits oxidative stress and antagonizes Alzheimer's disease by up-regulating SIRT1.
Pathological mutations in PNKP trigger defects in DNA single-strand break repair but not DNA double-strand break repair.
Integrative Proteomic Characterization of Human Lung Adenocarcinoma.
SLC7A2 serves as a potential biomarker and therapeutic target for ovarian cancer.
Protective effect of miRNA-containing extracellular vesicles derived from mesenchymal stromal cells of old rats on renal function in chronic kidney disease.
SNHG11 promotes cell proliferation in colorectal cancer by forming a positive regulatory loop with c-Myc.
The miR-1224-5p/TNS4/EGFR axis inhibits tumour progression in oesophageal squamous cell carcinoma.
Transcriptome Analysis of Testes and Uterus: Reproductive Dysfunction Induced by Toxoplasma gondii in Mice.
NLRP3 inflammasome-mediated microglial pyroptosis is critically involved in the development of post-cardiac arrest brain injury.
Innate Effector Systems in Primary Human Macrophages Sensitize Multidrug-Resistant Klebsiella pneumoniae to Antibiotics.
ZIC2 is downregulated and represses tumor growth via the regulation of STAT3 in breast cancer.
Impairment in dynein-mediated nuclear translocation by BICD2 C-terminal truncation leads to neuronal migration defect and human brain malformation.
Genetic variants in m6A modification genes are associated with esophageal squamous-cell carcinoma in the Chinese population.
Long non-coding RNA JPX correlates with poor prognosis and tumor progression in non-small-cell lung cancer by interacting with miR-145-5p and CCND2.
Excessive Mg2+ Impairs Intestinal Homeostasis by Enhanced Production of Adenosine Triphosphate and Reactive Oxygen Species.
Carfilzomib inhibits the growth of lung adenocarcinoma via upregulation of Gadd45a expression.
Identification and characterization of c-raf from orange-spotted grouper (Epinephelus coioides).
MiR-203a-3p inhibits retinal angiogenesis and alleviates proliferative diabetic retinopathy in oxygen-induced retinopathy (OIR) rat model via targeting VEGFA and HIF-1α.
Calycosin-7-O-β-D-glucoside attenuates myocardial ischemia-reperfusion injury by activating JAK2/STAT3 signaling pathway via the regulation of IL-10 secretion in mice.
MiR-183-5p protects rat hearts against myocardial ischemia/reperfusion injury through targeting VDAC1.
Decreased ALCAM expression and promoter hypermethylation is associated with preeclampsia.
High Expression of c-Met, PKCλ and ALDH1A3 Predicts a Poor Prognosis in Late-stage Breast Cancer.
ALKATI interacts with c-Myc and promotes cancer stem cell-like properties in sarcoma.
MnTBAP inhibits bone loss in ovariectomized rats by reducing mitochondrial oxidative stress in osteoblasts.
LncRNA SNHG3 promotes cell proliferation and invasion through the miR-384/hepatoma-derived growth factor axis in breast cancer.
Hydrogen sulfide attenuates cigarette smoke-induced airway remodeling by upregulating SIRT1 signaling pathway.
Human mesenchymal stem cells-derived conditioned medium inhibits hypoxia-induced death of neonatal porcine islets by inducing autophagy.
LncRNA HOXA11-AS regulates calcium oxalate crystal-induced renal inflammation via miR-124-3p/MCP-1.
Arsenic influences spermatogenesis by disorganizing the elongation of spermatids in adult male mice.
Endoplasmic reticulum stress regulates epithelial‑mesenchymal transition in human lens epithelial cells.
Effects of oral florfenicol on intestinal structure, function and microbiota in mice.
MicroRNA-138 inhibits tumor growth and enhances chemosensitivity in human cervical cancer by targeting H2AX.
REDD1 overexpression in oral squamous cell carcinoma may predict poor prognosis and correlates with high microvessel density.
USP12 translocation maintains interferon antiviral efficacy by inhibiting CBP acetyltransferase activity.
The novel thioredoxin reductase inhibitor A-Z2 triggers intrinsic apoptosis and shows efficacy in the treatment of acute myeloid leukemia.
Osthole inhibits cell proliferation by regulating the TGF-β1/Smad/p38 signaling pathways in pulmonary arterial smooth muscle cells.
Tandem mass tag (TMT) proteomic analysis of fetal lungs revealed differential expression of tight junction proteins in a rat model of congenital diaphragmatic hernia.
Activation of CD137 signaling promotes neointimal formation by attenuating TET2 and transferrring from endothelial cell-derived exosomes to vascular smooth muscle cells.
LncRNA GAS5 exacerbates renal tubular epithelial fibrosis by acting as a competing endogenous RNA of miR-96-5p.
Isolated Erythrocytosis Associated With 3 Novel Missense Mutations in the EGLN1 Gene.
Acetyltransferase GCN5 regulates autophagy and lysosome biogenesis by targeting TFEB.
5-(3,4,5-trimethoxybenzoyl)-4-methyl-2-(p-tolyl) imidazol (BZML) targets tubulin and DNA to induce anticancer activity and overcome multidrug resistance in colorectal cancer cells.
Resveratrol targets PD-L1 glycosylation and dimerization to enhance antitumor T-cell immunity.
The tight junction protein TJP1 regulates the feeding-modulated hepatic circadian clock.
Porphyromonas gingivalis triggers inflammatory responses in periodontal ligament cells by succinate-succinate dehydrogenase-HIF-1α axis.
Alisol A-24-acetate promotes glucose uptake via activation of AMPK in C2C12 myotubes.
Schnurri-3 regulates BMP9-induced osteogenic differentiation and angiogenesis of human amniotic mesenchymal stem cells through Runx2 and VEGF.
Calcium relieves fluoride-induced bone damage through the PI3K/AKT pathway.
Graphene Oxide Promotes Cancer Metastasis through Associating with Plasma Membrane To Promote TGF-β Signaling-Dependent Epithelial-Mesenchymal Transition.
GSPE alleviates renal fibrosis by inhibiting the activation of C3/ HMGB1/ TGF-β1 pathway.
An insertion mutation of ERBB2 enhances breast cancer cell growth and confers resistance to lapatinib through AKT signaling pathway.
miR-485 suppresses inflammation and proliferation of mesangial cells in an in vitro model of diabetic nephropathy by targeting NOX5.
FAM60A, increased by Helicobacter pylori, promotes proliferation and suppresses apoptosis of gastric cancer cells by targeting the PI3K/AKT pathway.
The Nuclear Matrix Protein SAFB Cooperates with Major Satellite RNAs to Stabilize Heterochromatin Architecture Partially through Phase Separation.
K562 cell-derived exosomes suppress the adhesive function of bone marrow mesenchymal stem cells via delivery of miR-711.
Fangchinoline derivatives induce cell cycle arrest and apoptosis in human leukemia cell lines via suppression of the PI3K/AKT and MAPK signaling pathway.
Microglia P2X4R-BDNF signalling contributes to central sensitization in a recurrent nitroglycerin-induced chronic migraine model.
DEF Cell-Derived Exosomal miR-148a-5p Promotes DTMUV Replication by Negative Regulating TLR3 Expression.
Endogenous production of C-C motif chemokine ligand 2 by nasopharyngeal carcinoma cells drives radioresistance-associated metastasis.
Schizandrin B Mitigates Rifampicin-Induced Liver Injury by Inhibiting Endoplasmic Reticulum Stress.
Regulation of the firing activity by PKA-PKC-Src family kinases in cultured neurons of hypothalamic arcuate nucleus.
PITPNC1 fuels radioresistance of rectal cancer by inhibiting reactive oxygen species production.
Chronic toxicity of methamphetamine: Oxidative remodeling of pulmonary arteries.
Beta-Amyloid Increases the Expression Levels of Tid1 Responsible for Neuronal Cell Death and Amyloid Beta Production.
Association between different levels of lipid metabolism‑related enzymes and fatty acid synthase in Wilms' tumor.
BDNF-TrkB pathway mediates antidepressant-like roles of H2 S in diabetic rats via promoting hippocampal autophagy.
Transcription factor RUNX2 regulates epithelial‑mesenchymal transition and progression in renal cell carcinomas.
Sirtuin 3 induces apoptosis and necroptosis by regulating mutant p53 expression in small‑cell lung cancer.
Visfatin Exerts Immunotherapeutic Effects in Lipopolysaccharide-Induced Acute Lung Injury in Murine Model.
Lactobacillus johnsonii L531 ameliorates enteritis via elimination of damaged mitochondria and suppression of SQSTM1-dependent mitophagy in a Salmonella infantis model of piglet diarrhea.
Berberine inhibits proliferation and migration of colorectal cancer cells by downregulation of GRP78.
RhoB is regulated by hypoxia and modulates metastasis in breast cancer.
Polychlorinated biphenyl quinone promotes macrophage polarization to CD163+ cells through Nrf2 signaling pathway.
LncRNA HRCEG, regulated by HDAC1, inhibits cells proliferation and epithelial-mesenchymal-transition in gastric cancer.
Mitochondrial respiratory chain damage and mitochondrial fusion disorder are involved in liver dysfunction of fluoride-induced mice.
Effects of Starvation on Antioxidant-Related Signaling Molecules, Oxidative Stress, and Autophagy in Juvenile Chinese Perch Skeletal Muscle.
Involvement of neurotrophic signaling in doxorubicin-induced cardiotoxicity.
1,3-Dicaffeoylquinic acid targeting 14-3-3 tau suppresses human breast cancer cell proliferation and metastasis through IL6/JAK2/PI3K pathway.
Discovery of a first-in-class EZH2 selective degrader.
PDE9 inhibition promotes proliferation of neural stem cells via cGMP-PKG pathway following oxygen-glucose deprivation/reoxygenation injury in vitro.
Predictive Value of Pin1 in Cervical Low-Grade Squamous Intraepithelial Lesions and Inhibition of Pin1 Exerts Potent Anticancer Activity against Human Cervical Cancer.
Ferrostatin-1 mitigates cognitive impairment of epileptic rats by inhibiting P38 MAPK activation.
The Combination of Fasting, Acute Resistance Exercise, and Protein Ingestion Led to Different Responses of Autophagy Markers in Gastrocnemius and Liver Samples.
MicroRNA-377-3p alleviates IL-1β-caused chondrocyte apoptosis and cartilage degradation in osteoarthritis in part by downregulating ITGA6.
RNA Binding Protein RNPC1 Suppresses the Stemness of Human Endometrial Cancer Cells via Stabilizing MST1/2 mRNA.
Targeting UBE4A Revives Viperin Protein in Epithelium to Enhance Host Antiviral Defense.
Polyphyllin VII attenuated RANKL-induced osteoclast differentiation via inhibiting of TRAF6/c-Src/PI3K pathway and ROS production.
GRWD1 promotes cell proliferation and migration in non-small cell lung cancer by activating the Notch pathway.
Network Pharmacology-Based Prediction and Verification of Qingluo Tongbi Formula to Reduce Liver Toxicity of Tripterygium wilfordii via UGT2B7 in Endoplasmic Reticulum.
PRL/microRNA-183/IRS1 Pathway Regulates Milk Fat Metabolism in Cow Mammary Epithelial Cells.
Doublecortin undergo nucleocytoplasmic transport via the RanGTPase signaling to promote glioma progression.
Curcumin Protects Human Trophoblast HTR8/SVneo Cells from H2O2-Induced Oxidative Stress by Activating Nrf2 Signaling Pathway.
Protective effect of resveratrol on obesity-related osteoarthritis via alleviating JAK2/STAT3 signaling pathway is independent of SOCS3.
PTP1B promotes macrophage activation by regulating the NF-κB pathway in alcoholic liver injury.
Silencing of DsbA-L gene impairs the PPARγ agonist function of improving insulin resistance in a high-glucose cell model.
SUMOylation of Pdia3 exacerbates proinsulin misfolding and ER stress in pancreatic beta cells.
LXA4 protects against hypoxic-ischemic damage in neonatal rats by reducing the inflammatory response via the IκB/NF-κB pathway.
Annexin A3 upregulates the infiltrated neutrophil-lymphocyte ratio to remodel the immune microenvironment in hepatocellular carcinoma.
Angiopoietin-like protein 4 promotes very-low-density lipoprotein assembly and secretion in bovine hepatocytes in vitro.
Quercetin alleviates neonatal hypoxic-ischemic brain injury by inhibiting microglia-derived oxidative stress and TLR4-mediated inflammation.
Knockdown of eukaryotic translation initiation factor 5A2 enhances the therapeutic efficiency of doxorubicin in hepatocellular carcinoma cells by triggering lethal autophagy.
Nobiletin Ameliorates NLRP3 Inflammasome-Mediated Inflammation Through Promoting Autophagy via the AMPK Pathway.
An antiviral drug-resistant mutant of hepatitis B virus with high replication capacity in association with a large in-frame deletion in the preS1 region of viral surface gene.
Intratunical injection of human urine-derived stem cells derived exosomes prevents fibrosis and improves erectile function in a rat model of Peyronie's disease.
MMP7 damages the integrity of the renal tubule epithelium by activating MMP2/9 during ischemia-reperfusion injury.
Down-Regulated CUEDC2 Increases GDNF Expression by Stabilizing CREB Through Reducing Its Ubiquitination in Glioma.
Aberrant expression of miRNA-192-5p contributes to N,N-dimethylformamide-induced hepatic apoptosis.
Histone demethylase JHDM2A regulates H3K9 dimethylation in response to arsenic-induced DNA damage and repair in normal human liver cells.
Inhibition of ACSL4 attenuates ferroptotic damage after pulmonary ischemia-reperfusion.
PFOS-induced placental cell growth inhibition is partially mediated by lncRNA H19 through interacting with miR-19a and miR-19b.
Molecular identification, tissue distribution and in vitro functional analysis of growth hormone and its receptors in red-spotted grouper (Epinephelus akaara).
Inhibition of CACNA1H can alleviate endoplasmic reticulum stress and reduce myocardial cell apoptosis caused by myocardial infarction.
FABP4 inhibitor attenuates inflammation and endoplasmic reticulum stress of islet in leptin receptor knockout rats.
Polarization of ADAM17-driven EGFR signalling in electric field-guided collective migration of epidermal sheets.
The proinflammatory cytokines IL-1β and TNF-α modulate corneal epithelial wound healing through p16Ink4a suppressing STAT3 activity.
miR-448-3p alleviates diabetic vascular dysfunction by inhibiting endothelial-mesenchymal transition through DPP-4 dysregulation.
Inhibition of p38 MAPK regulates epileptic severity by decreasing expression levels of A1R and ENT1.
Effect of TFAM on ATP content in tachypacing primary cultured cardiomyocytes and atrial fibrillation patients.
IGFBP‑rP1‑silencing promotes hypoxia‑induced angiogenic potential of choroidal endothelial cells via the RAF/MEK/ERK signaling pathway.
Pseudolaric acid B induces apoptosis in human rhabdomyosarcoma RD cells.
A Combination of BRD4 and HDAC3 Inhibitors Synergistically Suppresses Glioma Stem Cell Growth by Blocking GLI1/IL6/STAT3 Signaling Axis.
Resveratrol improves meat quality, muscular antioxidant capacity, lipid metabolism and fiber type composition of intrauterine growth retarded pigs.
Polymethoxyflavones from citrus inhibited gastric cancer cell proliferation through inducing apoptosis by upregulating RARβ, both in vitro and in vivo.
Cannabinoid receptor subtype influence on neuritogenesis in human SH-SY5Y cells.
Andrographolide exerts anti-inflammatory effects in Mycobacterium tuberculosis-infected macrophages by regulating the Notch1/Akt/NF-κB axis.
Structural and Functional Characterization of Host FHL1 Protein Interaction with Hypervariable Domain of Chikungunya Virus nsP3 Protein.
β-Elemene enhances radiosensitivity in non-small-cell lung cancer by inhibiting epithelial-mesenchymal transition and cancer stem cell traits via Prx-1/NF-kB/iNOS signaling pathway.
Condensation of Rubisco into a proto-pyrenoid in higher plant chloroplasts.
Exploration of the Effects of Substrate Stiffness on Biological Responses of Neural Cells and Their Mechanisms.
circ_2858 Helps Blood-Brain Barrier Disruption by Increasing VEGFA via Sponging miR-93-5p during Escherichia coli Meningitis.
Metabotropic glutamate receptor 5 regulates synaptic plasticity in a chronic migraine rat model through the PKC/NR2B signal.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) membrane (M) protein inhibits type I and III interferon production by targeting RIG-I/MDA-5 signaling.
TRIM24 promotes stemness and invasiveness of glioblastoma cells via activating Sox2 expression.
RIPK1 Distinctly Regulates Yersinia-Induced Inflammatory Cell Death, PANoptosis.
Ubiquitination of RIPK1 regulates its activation mediated by TNFR1 and TLRs signaling in distinct manners.
Exploring the mechanism of cisplatin resistance by transcriptome sequencing and reversing the chemoresistance by autophagy inhibition in small cell lung cancer.
Podocyte-derived extracellular vesicles mediate renal proximal tubule cells dedifferentiation via microRNA-221 in diabetic nephropathy.
PhospholipaseCγ1/calcium-dependent membranous localization of Gsdmd-N drives endothelial pyroptosis, contributing to lipopolysaccharide-induced fatal outcome.
Effects of taraxasterol against ethanol and high-fat diet-induced liver injury by regulating TLR4/MyD88/NF-κB and Nrf2/HO-1 signaling pathways.
NPY stimulates cholesterol synthesis acutely by activating the SREBP2-HMGCR pathway through the Y1 and Y5 receptors in murine hepatocytes.
Prostaglandin I2 mediates weak vasodilatation in human placental microvessels.
HOTAIR promotes paclitaxel resistance by regulating CHEK1 in ovarian cancer.
Ginsenoside Rk3 alleviated DSS-induced ulcerative colitis by protecting colon barrier and inhibiting NLRP3 inflammasome pathway.
Metformin inhibits extracellular matrix accumulation, inflammation and proliferation of mesangial cells in diabetic nephropathy by regulating H19/miR-143-3p/TGF-β1 axis.
GOLPH3 Regulates Exosome miRNA Secretion in Glioma Cells.
Metabolomic profiling reveals similar cytotoxic effects and protective functions of quercetin during deoxynivalenol- and 15-acetyl deoxynivalenol-induced cell apoptosis.
All-Trans Retinoic Acid Exerts Neuroprotective Effects in Amyotrophic Lateral Sclerosis-Like Tg (SOD1*G93A)1Gur Mice.
Exopolysaccharide from Cryptococcus heimaeyensis S20 induces autophagic cell death in non-small cell lung cancer cells via ROS/p38 and ROS/ERK signalling.
Role of Zinc Sulphate in Immune Regulation in Artemisia annua Pollen-challenged P815 Mastocytoma Cells.
Exogenous spermine attenuates myocardial fibrosis in diabetic cardiomyopathy by inhibiting endoplasmic reticulum stress and the canonical Wnt signaling pathway.
Setosphapyrone C and D accelerate macrophages cholesterol efflux by promoting LXRα/ABCA1 pathway.
Thymidine phosphorylase promotes angiogenesis and tumour growth in intrahepatic cholangiocarcinoma.
Downregulation of miR-140-5p affects the pathogenesis of HSCR by targeting EGR2.
Inhibition of the facilitative sugar transporters (GLUTs) by tea extracts and catechins.
Lnc00462717 regulates the permeability of the blood-brain tumor barrier through interaction with PTBP1 to inhibit the miR-186-5p/Occludin signaling pathway.
USP30 sets a trigger threshold for PINK1-PARKIN amplification of mitochondrial ubiquitylation.
Pseudorabies virus infection inhibits stress granules formation via dephosphorylating eIF2α.
Protective effect of exogenous hydrogen sulfide on diaphragm muscle fibrosis in streptozotocin-induced diabetic rats.
Cell cycle exit during bortezomib-induced osteogenic differentiation of mesenchymal stem cells was mediated by Xbp1s-upregulated p21Cip1 and p27Kip1.
Salvianic acid A alleviates chronic alcoholic liver disease by inhibiting HMGB1 translocation via down-regulating BRD4.
Septin4 regulates endoplasmic reticulum stress and apoptosis in melatonin‑induced osteoblasts.
Overexpression of negative regulator of ubiquitin-like proteins 1 (NUB1) inhibits proliferation and invasion of gastric cancer cells through upregulation of p27Kip1 and inhibition of epithelial-mesenchymal transition.
Overexpression of B7-H4 promotes renal cell carcinoma progression by recruiting tumor-associated neutrophils via upregulation of CXCL8.
Hsa-miR-425-5p promotes tumor growth and metastasis by activating the CTNND1-mediated β-catenin pathway and EMT in colorectal cancer.
Catalase is required for peroxisome maintenance during adipogenesis.
Targeting G6PD reverses paclitaxel resistance in ovarian cancer by suppressing GSTP1.
Localization of ZIP14 and ZIP8 in HIBCPP Cells.
Reelin Promotes Cisplatin Resistance by Induction of Epithelial-Mesenchymal Transition via p38/GSK3β/Snail Signaling in Non-Small Cell Lung Cancer.
STIM1-mediated calcium influx controls antifungal immunity and the metabolic function of non-pathogenic Th17 cells.
Selective Translation of Cell Fate Regulators Mediates Tolerance to Broad Oncogenic Stress.
Development of a Cationic Amphiphilic Helical Peptidomimetic (B18L) As A Novel Anti-Cancer Drug Lead.
Hippuric Acid Promotes Renal Fibrosis by Disrupting Redox Homeostasis via Facilitation of NRF2-KEAP1-CUL3 Interactions in Chronic Kidney Disease.
Cotargeting of Mitochondrial Complex I and Bcl-2 Shows Antileukemic Activity against Acute Myeloid Leukemia Cells Reliant on Oxidative Phosphorylation.
α-Mangostin, a Dietary Xanthone, Exerts Protective Effects on Cisplatin-Induced Renal Injury via PI3K/Akt and JNK Signaling Pathways in HEK293 Cells.
Tetrandrine enhances glucocorticoid receptor translocation possibly via inhibition of P-glycoprotein in daunorubicin-resistant human T lymphoblastoid leukemia cells.
Bcl2 inhibitor ABT737 reverses the Warburg effect via the Sirt3-HIF1α axis to promote oxidative stress-induced apoptosis in ovarian cancer cells.
Lactobacillus johnsonii L531 Ameliorates Escherichia coli-Induced Cell Damage via Inhibiting NLRP3 Inflammasome Activity and Promoting ATG5/ATG16L1-Mediated Autophagy in Porcine Mammary Epithelial Cells.
Plakoglobin is involved in cytoskeletal rearrangement of podocytes under the regulation of UCH-L1.
Flavagline synthetic derivative induces senescence in glioblastoma cancer cells without being toxic to healthy astrocytes.
Acetylation of Cytidine Residues Boosts HIV-1 Gene Expression by Increasing Viral RNA Stability.
Cultivation of Hair Matrix Cells from Cashmere Goat Skins and Exemplified Applications.
The Small Molecule P7C3-A20 Exerts Neuroprotective Effects in a Hypoxic-ischemic Encephalopathy Model via Activation of PI3K/AKT/GSK3β Signaling.
TMT-based proteomics analysis reveals the protective effects of Xuefu Zhuyu decoction in a rat model of traumatic brain injury.
Lignans from Schisandra chinensis ameliorate alcohol and CCl4-induced long-term liver injury and reduce hepatocellular degeneration via blocking ETBR.
Role of ion channels in chronic intermittent hypoxia-induced atrial remodeling in rats.
TLR4 knockout upregulates the expression of Mfn2 and PGC-1α in a high-fat diet and ischemia-reperfusion mice model of liver injury.
Comparative analysis of two brine shrimps revealed differential expression pattern and functional characterization of CK2α under bacterial stimulation from different geographical distribution.
Fangjihuangqi Decoction inhibits MDA-MB-231 cell invasion in vitro and decreases tumor growth and metastasis in triple-negative breast cancer xenografts tumor zebrafish model.
Berberine combined with cyclosporine A alleviates acute graft-versus-host disease in murine models.
Long non-coding RNA LOC100133669 promotes cell proliferation in oesophageal squamous cell carcinoma.
Retinoid X receptor α (RXRα)-mediated erythroid-2-related factor-2 (NRF2) inactivation contributes to N,N-dimethylformamide (DMF)-induced oxidative stress in HL-7702 and HuH6 cells.
The Potential Role of PKA/CREB Signaling Pathway Concerned with Gastrodin Administration on Methamphetamine-Induced Conditioned Place Preference Rats and SH-SY5Y Cell Line.
Virus analog decreases estradiol secretion in FSH-treated human ovarian granulosa cells.
The deletion of mutant SOD1 via CRISPR/Cas9/sgRNA prolongs survival in an amyotrophic lateral sclerosis mouse model.
MiR-129-5p protects against myocardial ischemia-reperfusion injury via targeting HMGB1.
Targeting STAT3 enhances NDV-induced immunogenic cell death in prostate cancer cells.
GLL398, an oral selective estrogen receptor degrader (SERD), blocks tumor growth in xenograft breast cancer models.
IL-29 promoted obesity-induced inflammation and insulin resistance.
NEK2 induces autophagy-mediated bortezomib resistance by stabilizing Beclin-1 in multiple myeloma.
A novel Sprouty4-ERK1/2-Wnt/β-catenin regulatory loop in marrow stromal progenitor cells controls osteogenic and adipogenic differentiation.
Myxovirus resistance (Mx) gene and its differential expression regulated by three type I and two type II IFNs in mandarin fish, Siniperca chuatsi.
p53-mediated control of aspartate-asparagine homeostasis dictates LKB1 activity and modulates cell survival.
A Combination of Formic Acid and Monolaurin Attenuates Enterotoxigenic Escherichia coli Induced Intestinal Inflammation in Piglets by Inhibiting the NF-κB/MAPK Pathways with Modulation of Gut Microbiota.
Synergistic Neuroprotective Effect of Endogenously-Produced Hydroxytyrosol and Synaptic Vesicle Proteins on Pheochromocytoma Cell Line Against Salsolinol.
Interaction between PHB2 and Enterovirus A71 VP1 Induces Autophagy and Affects EV-A71 Infection.
Anti-neuroinflammatory effects of dimethylaminomylide (DMAMCL, i.e., ACT001) are associated with attenuating the NLRP3 inflammasome in MPTP-induced Parkinson disease in mice.
MicroRNA-574-5p in gastric cancer cells promotes angiogenesis by targeting protein tyrosine phosphatase non-receptor type 3 (PTPN3).
Effect of fluoride on osteocyte-driven osteoclastic differentiation.
Caspase-6 Is a Key Regulator of Innate Immunity, Inflammasome Activation, and Host Defense.
Decreased ZNF750 promotes angiogenesis in a paracrine manner via activating DANCR/miR-4707-3p/FOXC2 axis in esophageal squamous cell carcinoma.
Cold atmospheric plasma induces GSDME-dependent pyroptotic signaling pathway via ROS generation in tumor cells.
4β-Hydroxywithanolide E from Goldenberry (Whole Fruits of Physalis peruviana L.) as a Promising Agent against Chronic Obstructive Pulmonary Disease.
HIF-1β Positively Regulates NF-κB Activity via Direct Control of TRAF6.
Maternal curcumin supplementation ameliorates placental function and fetal growth in mice with intrauterine growth retardation†.
Pathogenic Variants in CEP85L Cause Sporadic and Familial Posterior Predominant Lissencephaly.
Soluble epoxide hydrolase inhibitor protects against blood-brain barrier dysfunction in a mouse model of type 2 diabetes via the AMPK/HO-1 pathway.
AcMNPV PKIP is required for hyperexpression of very late genes and involved in the hyperphosphorylation of the viral basic protein P6.9.
Circadian clock gene Clock is involved in the pathogenesis of preeclampsia through hypoxia.
STIM2 knockdown protects against ischemia/reperfusion injury through reducing mitochondrial calcium overload and preserving mitochondrial function.
The SCFβ-TrCP E3 Ubiquitin Ligase Regulates Immune Receptor Signaling by Targeting the Negative Regulatory Protein TIPE2.
Physicochemical characterization of polysaccharide from the leaf of Dendrobium officinale and effect on LPS induced damage in GES-1 cell.
Trehalose attenuates renal ischemia-reperfusion injury by enhancing autophagy and inhibiting oxidative stress and inflammation.
Localized injection of miRNA-21-enriched extracellular vesicles effectively restores cardiac function after myocardial infarction.
HSF2 regulates aerobic glycolysis by suppression of FBP1 in hepatocellular carcinoma.
Oncogenic MSH6-CXCR4-TGFB1 Feedback Loop: A Novel Therapeutic Target of Photothermal Therapy in Glioblastoma Multiforme.
Targeting mitochondrial dynamics by regulating Mfn2 for therapeutic intervention in diabetic cardiomyopathy.
Triptolide Induces Glioma Cell Autophagy and Apoptosis via Upregulating the ROS/JNK and Downregulating the Akt/mTOR Signaling Pathways.
Identification of RE1-Silencing Transcription Factor as a Promoter of Metastasis in Pancreatic Cancer.
Inhibition of oxidative stress by testosterone improves synaptic plasticity in senescence accelerated mice.
Evidence for interaction of the NLRP3 inflammasome and Bruton's tyrosine kinase in tumor-associated macrophages: implications for myeloid cell production of interleukin-1beta.
Bergenin Ameliorates MPTP-Induced Parkinson's Disease by Activating PI3K/Akt Signaling Pathway.
aFGF Promotes Neurite Growth by Regulating GSK3β-CRMP2 Signaling Pathway in Cortical Neurons Damaged by Amyloid-β.
Synergetic Inhibition of Human Colorectal Cancer Cells by Combining Polyyne-Enriched Fraction from Oplopanax elatus and Irinotecan.
MiR-223-3p Alleviates Vascular Endothelial Injury by Targeting IL6ST in Kawasaki Disease.
Loss of the Golgi Matrix Protein 130 Cause Aberrant IgA1 Glycosylation in IgA Nephropathy.
Chemo-Preventive Potential of Falcarindiol-Enriched Fraction from Oplopanax elatus on Colorectal Cancer Interfered by Human Gut Microbiota.
Cinobufagin Promotes Cell Cycle Arrest and Apoptosis to Block Human Esophageal Squamous Cell Carcinoma Cells Growth via the p73 Signalling Pathway.
Loss of Mitochondrial DNA by Gemcitabine Triggers Mitophagy and Cell Death.
RNA-seq analysis of PHD and VHL inhibitors reveals differences and similarities to the hypoxia response.
The Role of Nrf2 Signaling Pathway in Eucommia ulmoides Flavones Regulating Oxidative Stress in the Intestine of Piglets.
Dexmedetomidine Attenuates Orthotopic Liver Transplantation-Induced Acute Gut Injury via α 2-Adrenergic Receptor-Dependent Suppression of Oxidative Stress.
Paneth Cell Ablation Aggravates Pancreatic and Intestinal Injuries in a Rat Model of Acute Necrotizing Pancreatitis after Normal and High-Fat Diet.
Palmitic Acid Induces MicroRNA-221 Expression to Decrease Glucose Uptake in HepG2 Cells via the PI3K/AKT/GLUT4 Pathway.
Tetrandrine-Induced Autophagy in MDA-MB-231 Triple-Negative Breast Cancer Cell through the Inhibition of PI3K/AKT/mTOR Signaling.
N-n-Butyl Haloperidol Iodide Ameliorates Oxidative Stress in Mitochondria Induced by Hypoxia/Reoxygenation through the Mitochondrial c-Jun N-Terminal Kinase/Sab/Src/Reactive Oxygen Species Pathway in H9c2 Cells.
Oral Administration of Lactobacillus delbrueckii during the Suckling Phase Improves Antioxidant Activities and Immune Responses after the Weaning Event in a Piglet Model.
Minocycline Protects against Rotenone-Induced Neurotoxicity Correlating with Upregulation of Nurr1 in a Parkinson's Disease Rat Model.
Phosphocreatine Improves Cardiac Dysfunction by Normalizing Mitochondrial Respiratory Function through JAK2/STAT3 Signaling Pathway In Vivo and In Vitro.
CD133 Is Associated with Increased Melanoma Cell Survival after Multikinase Inhibition.
CTGF Attenuates Tendon-Derived Stem/Progenitor Cell Aging.
Reactive Oxygen Species Are Involved in the Development of Gastric Cancer and Gastric Cancer-Related Depression through ABL1-Mediated Inflammation Signaling Pathway.
Purple Sweet Potato Color Attenuates Kidney Damage by Blocking VEGFR2/ROS/NLRP3 Signaling in High-Fat Diet-Treated Mice.
Nicorandil Attenuates LPS-Induced Acute Lung Injury by Pulmonary Endothelial Cell Protection via NF-κB and MAPK Pathways.
Shuangyu Tiaozhi Granule Attenuates Hypercholesterolemia through the Reduction of Cholesterol Synthesis in Rat Fed a High Cholesterol Diet.
Prevention of Huntington's Disease-Like Behavioral Deficits in R6/1 Mouse by Tolfenamic Acid Is Associated with Decreases in Mutant Huntingtin and Oxidative Stress.
Bu Shen Zhu Yun Decoction Improves Endometrial Receptivity via VEGFR-2-Mediated Angiogenesis.
Yiqihuoxue Formula Activates Autophagy and Offers Renoprotection in a Rat Model of Adenine-Induced Kidney Disease.
Curcumin and Curcumol Inhibit NF-κB and TGF-β 1/Smads Signaling Pathways in CSE-Treated RAW246.7 Cells.
Astragalus Membranaceus Treatment Protects Raw264.7 Cells from Influenza Virus by Regulating G1 Phase and the TLR3-Mediated Signaling Pathway.
Salvianolic Acid A Protects the Kidney against Oxidative Stress by Activating the Akt/GSK-3β/Nrf2 Signaling Pathway and Inhibiting the NF-κB Signaling Pathway in 5/6 Nephrectomized Rats.
Stem Cells from Human Exfoliated Deciduous Teeth Ameliorate Diabetic Nephropathy In Vivo and In Vitro by Inhibiting Advanced Glycation End Product-Activated Epithelial-Mesenchymal Transition.
Leukemia Inhibitory Factor Receptor Is Involved in Apoptosis in Rat Astrocytes Exposed to Oxygen-Glucose Deprivation.
Astragaloside IV Suppresses High Glucose-Induced NLRP3 Inflammasome Activation by Inhibiting TLR4/NF-κB and CaSR.
miR-100-3p inhibits cell proliferation and induces apoptosis in human gastric cancer through targeting to BMPR2.
SSRP1 influences colorectal cancer cell growth and apoptosis via the AKT pathway.
Fucoidan prevent murine autoimmune diabetes via suppression TLR4-signaling pathways, regulation DC/Treg induced immune tolerance and improving gut microecology.
CXXC5 Mediates P. gingivalis-suppressed Cementoblast Functions Partially via MAPK Signaling Network.
Fructose-1,6-bisphosphate prevents pulmonary fibrosis by regulating extracellular matrix deposition and inducing phenotype reversal of lung myofibroblasts.
SPSB2 inhibits hepatitis C virus replication by targeting NS5A for ubiquitination and degradation.
Resveratrol induced premature senescence and inhibited epithelial-mesenchymal transition of cancer cells via induction of tumor suppressor Rad9.
The Pseudogene PTTG3P Promotes Cell Migration and Invasion in Esophageal Squamous Cell Carcinoma.
Synergism of cisplatin-oleanolic acid co-loaded calcium carbonate nanoparticles on hepatocellular carcinoma cells for enhanced apoptosis and reduced hepatotoxicity.
Treatment With Liraglutide Exerts Neuroprotection After Hypoxic-Ischemic Brain Injury in Neonatal Rats via the PI3K/AKT/GSK3β Pathway.
Overexpression of CX3CR1 in Adipose-Derived Stem Cells Promotes Cell Migration and Functional Recovery After Experimental Intracerebral Hemorrhage.
Arsenic sulfide induces miR-4665-3p to inhibit gastric cancer cell invasion and migration.
Hydrogen Sulfide Attenuates β2-Microglobulin-Induced Cognitive Dysfunction: Involving Recovery of Hippocampal Autophagic Flux.
Necrostatin-1 Ameliorates Peripheral Nerve Injury-Induced Neuropathic Pain by Inhibiting the RIP1/RIP3 Pathway.
The Neuroprotection of KIBRA in Promoting Neuron Survival and Against Amyloid β-Induced Apoptosis.
SUMOylation and deacetylation affect NF-κB p65 activity induced by high glucose in human lens epithelial cells.
Gatifloxacin inducing apoptosis of stromal fibroblasts through cross-talk between caspase-dependent extrinsic and intrinsic pathways.
Expression Of BMP7 In Ovarian Cancer And Biological Effect Of BMP7 Knockdown On Ovarian Cancer Cells.
MicroRNA-765 sensitizes osteosarcoma cells to cisplatin via downregulating APE1 expression.
LAPTM4B knockdown increases the radiosensitivity of EGFR-overexpressing radioresistant nasopharyngeal cancer cells by inhibiting autophagy.
β-elemene inhibits radiation and hypoxia-induced macrophages infiltration via Prx-1/NF-κB/HIF-1α signaling pathway.
Exosomal Tenascin-c induces proliferation and invasion of pancreatic cancer cells by WNT signaling.
Multiple Functions of KBP in Neural Development Underlie Brain Anomalies in Goldberg-Shprintzen Syndrome.
Dichloroacetic acid upregulates apoptosis of ovarian cancer cells by regulating mitochondrial function.
miR-492 Promotes Cancer Progression by Targeting GJB4 and Is a Novel Biomarker for Bladder Cancer.
miR-509-5p Downregulation Is Associated With Male Infertility And Acts As A Suppressor In Testicular Germ Cell Tumor Cells Through Targeting MDM2.
Escin protects against acetaminophen-induced liver injury in mice via attenuating inflammatory response and inhibiting ERK signaling pathway.
MiR-302a-5p suppresses cell proliferation and invasion in non-small cell lung carcinoma by targeting ITGA6.
VASN promotes YAP/TAZ and EMT pathway in thyroid carcinogenesis in vitro.
Overexpression of CBX2 in breast cancer promotes tumor progression through the PI3K/AKT signaling pathway.
BPTF cooperates with p50 NF-κB to promote COX-2 expression and tumor cell growth in lung cancer.
Clinical roles of miR-136-5p and its target metadherin in thyroid carcinoma.
Downregulation of angiopoietin-like protein 2 inhibits cementoblast differentiation partially by activating the ERK1/2 signaling pathway.
ADAR1 may be involved in the proliferation of acute myeloid leukemia cells via regulation of the Wnt pathway.
Overexpressed PKMYT1 promotes tumor progression and associates with poor survival in esophageal squamous cell carcinoma.
HIF1α/miR-520a-3p/AKT1/mTOR Feedback Promotes The Proliferation And Glycolysis Of Gastric Cancer Cells.
STIP1 Regulates Proliferation and Migration of Lung Adenocarcinoma Through JAK2/STAT3 Signaling Pathway.
Inhibition of RNA-Binding Protein Musashi-1 Suppresses Malignant Properties and Reverses Paclitaxel Resistance in Ovarian Carcinoma.
CLEC4M is associated with poor prognosis and promotes cisplatin resistance in NSCLC patients.
Methylation of SLFN11 promotes gastric cancer growth and increases gastric cancer cell resistance to cisplatin.
EP300 as an oncogene correlates with poor prognosis in esophageal squamous carcinoma.
8-bromo-7-methoxychrysin targets NF-κB and FoxM1 to inhibit lung cancer stem cells induced by pro-inflammatory factors.
An NF90/long noncoding RNA-LET/miR-548k feedback amplification loop controls esophageal squamous cell carcinoma progression.
Verteporfin suppresses the proliferation, epithelial-mesenchymal transition and stemness of head and neck squamous carcinoma cells via inhibiting YAP1.
ITRAQ-Based Proteomics Analysis Reveals the Effect of Neoliensinine on KCl-Induced Vascular Smooth Muscle Contraction by Inhibiting Regulatory Light Chain Phosphorylation.
Discovery of N-(2-Aminophenyl)-4-(bis(2-chloroethyl)amino)Benzamide as a Potent Histone Deacetylase Inhibitor.
A Novel Regulatory Circuit "C/EBPα/miR-20a-5p/TOB2" Regulates Adipogenesis and Lipogenesis.
Effects of Exercise Training on the Autophagy-Related Muscular Proteins Expression in Ovariectomized Rats.
Irbesartan Ameliorates Lipid Deposition by Enhancing Autophagy via PKC/AMPK/ULK1 Axis in Free Fatty Acid Induced Hepatocytes.
Fish Autophagy Protein 5 Exerts Negative Regulation on Antiviral Immune Response Against Iridovirus and Nodavirus.
A Novel Postbiotic From Lactobacillus rhamnosus GG With a Beneficial Effect on Intestinal Barrier Function.
An improved Tet-on system in microRNA overexpression and CRISPR/Cas9-mediated gene editing.
Identification of a Novel Bcl-2 Inhibitor by Ligand-Based Screening and Investigation of Its Anti-cancer Effect on Human Breast Cancer Cells.
Prepartum body conditions affect insulin signaling pathways in postpartum adipose tissues in transition dairy cows.
Da-Bu-Yin-Wan and Qian-Zheng-San Ameliorate Mitochondrial Dynamics in the Parkinson's Disease Cell Model Induced by MPP.
The Involvement of Renin-Angiotensin System in Lipopolysaccharide-Induced Behavioral Changes, Neuroinflammation, and Disturbed Insulin Signaling.
Epstein-Barr Virus Nuclear Antigen 1 Recruits Cyclophilin A to Facilitate the Replication of Viral DNA Genome.
Dengue Virus Infection Activates Interleukin-1β to Induce Tissue Injury and Vascular Leakage.
Hypertensive Rats Treated Chronically With Nω-Nitro-L-Arginine Methyl Ester (L-NAME) Induced Disorder of Hepatic Fatty Acid Metabolism and Intestinal Pathophysiology.
Cathelicidin-WA Facilitated Intestinal Fatty Acid Absorption Through Enhancing PPAR-γ Dependent Barrier Function.
The Capsid Protein VP1 of Coxsackievirus B Induces Cell Cycle Arrest by Up-Regulating Heat Shock Protein 70.
LncRNA LUCRC Regulates Colorectal Cancer Cell Growth and Tumorigenesis by Targeting Endoplasmic Reticulum Stress Response.
Ghrelin Attenuates Neuroinflammation and Demyelination in Experimental Autoimmune Encephalomyelitis Involving NLRP3 Inflammasome Signaling Pathway and Pyroptosis.
An Improved Enzyme-Linked Focus Formation Assay Revealed Baloxavir Acid as a Potential Antiviral Therapeutic Against Hantavirus Infection.
LPS Induces Preeclampsia-Like Phenotype in Rats and HTR8/SVneo Cells Dysfunction Through TLR4/p38 MAPK Pathway.
Sorghum Phenolics Inhibits Inflammasomes in Lipopolysaccharide (LPS)-Primed and Adenosine Triphosphate (ATP)-Activated Macrophages.
Functional evidence for a de novo mutation in WDR45 leading to BPAN in a Chinese girl.
Aerobic Exercise Improves Synaptic-Related Proteins of Diabetic Rats by Inhibiting FOXO1/NF-κB/NLRP3 Inflammatory Signaling Pathway and Ameliorating PI3K/Akt Insulin Signaling Pathway.
Comparison of the Effects of Green and Black Tea Extracts on Na+ /K+ -ATPase Activity in Intestine of Type 1 and Type 2 Diabetic Mice.
Mechanosensitive ion channel Piezo1 promotes prostate cancer development through the activation of the Akt/mTOR pathway and acceleration of cell cycle.
MicroRNA-191 promotes hepatocellular carcinoma cell proliferation by has_circ_0000204/miR-191/KLF6 axis.
Cardiac troponin I autoantibody induces myocardial dysfunction by PTEN signaling activation.
DEPDC1 drives hepatocellular carcinoma cell proliferation, invasion and angiogenesis by regulating the CCL20/CCR6 signaling pathway.
Eukaryotic elongation factor-2 kinase regulates the cross-talk between autophagy and pyroptosis in doxorubicin-treated human melanoma cells in vitro.
The Functional Polymorphism R129W in the BVES Gene Is Associated with Sporadic Tetralogy of Fallot in the Han Chinese Population.
Ursolic acid suppresses the invasive potential of colorectal cancer cells by regulating the TGF-β1/ZEB1/miR-200c signaling pathway.
2',4'-Dihydroxy-6'-methoxy-3',5'-dimethylchalcone induced apoptosis and G1 cell cycle arrest through PI3K/AKT pathway in BEL-7402/5-FU cells.
HOXA11-AS regulates JAK-STAT pathway by miR-15a-3p/STAT3 axis to promote the growth and metastasis in liver cancer.
SARI attenuates colon inflammation by promoting STAT1 degradation in intestinal epithelial cells.
Induction of Nrf2 pathway by Dendrobium nobile Lindl. alkaloids protects against carbon tetrachloride induced acute liver injury.
A hidden human proteome encoded by 'non-coding' genes.
LINC01123, a c-Myc-activated long non-coding RNA, promotes proliferation and aerobic glycolysis of non-small cell lung cancer through miR-199a-5p/c-Myc axis.
CDK5-dependent phosphorylation and nuclear translocation of TRIM59 promotes macroH2A1 ubiquitination and tumorigenicity.
Applying vibration in early postmenopausal osteoporosis promotes osteogenic differentiation of bone marrow-derived mesenchymal stem cells and suppresses postmenopausal osteoporosis progression.
Fine particulate matters induce apoptosis via the ATM/P53/CDK2 and mitochondria apoptosis pathway triggered by oxidative stress in rat and GC-2spd cell.
NRF2-dependent gene expression promotes ciliogenesis and Hedgehog signaling.
MiR-143-3p directly targets GLUT9 to reduce uric acid reabsorption and inflammatory response of renal tubular epithelial cells.
Kinsenoside ameliorates intervertebral disc degeneration through the activation of AKT-ERK1/2-Nrf2 signaling pathway.
Accelerated Metabolite Levels of Aerobic Glycolysis and the Pentose Phosphate Pathway Are Required for Efficient Replication of Infectious Spleen and Kidney Necrosis Virus in Chinese Perch Brain Cells.
Long non-coding RNA, HOTAIRM1, promotes glioma malignancy by forming a ceRNA network.
Maltol (3-Hydroxy-2-methyl-4-pyrone) Slows d-Galactose-Induced Brain Aging Process by Damping the Nrf2/HO-1-Mediated Oxidative Stress in Mice.
Exosomes derived from cardiac progenitor cells attenuate CVB3-induced apoptosis via abrogating the proliferation of CVB3 and modulating the mTOR signaling pathways.
Bisdemethoxycurcumin Protection of Cardiomyocyte Mainly Depends on Nrf2/HO-1 Activation Mediated by the PI3K/AKT Pathway.
Regulatory effect of a Chinese herbal medicine formula on non-alcoholic fatty liver disease.
Artocarmitin B enhances intracellular antioxidant capacity via activation of Nrf2 signaling pathway in human lung epithelial cells.
Tetrandrine and cepharanthine induce apoptosis through caspase cascade regulation, cell cycle arrest, MAPK activation and PI3K/Akt/mTOR signal modification in glucocorticoid resistant human leukemia Jurkat T cells.
Astragaloside IV protects against hyperglycemia-induced vascular endothelial dysfunction by inhibiting oxidative stress and Calpain-1 activation.
The protective effects of Ghrelin/GHSR on hippocampal neurogenesis in CUMS mice.
Grouper Atg12 negatively regulates the antiviral immune response against Singapore grouper iridovirus (SGIV) infection.
MicroRNA-182-3p negatively regulates cytokines expression by targeting TLR5M in orange-spotted grouper, Epinephelus coioides.
Naringin mitigates myocardial strain and the inflammatory response in sepsis-induced myocardial dysfunction through regulation of PI3K/AKT/NF-κB pathway.
Rhein inhibits ATP-triggered inflammatory responses in rheumatoid rat fibroblast-like synoviocytes.
SIRT1-regulated HMGB1 release is partially involved in TLR4 signal transduction: A possible anti-neuroinflammatory mechanism of resveratrol in neonatal hypoxic-ischemic brain injury.
USP22 Deubiquitinates CD274 to Suppress Anticancer Immunity.
Overexpression of Limb-Bud and Heart (LBH) promotes angiogenesis in human glioma via VEGFA-mediated ERK signalling under hypoxia.
MiR-26a promotes fracture healing of nonunion rats possibly by targeting SOSTDC1 and further activating Wnt/β-catenin signaling pathway.
Ginsenoside compound K ameliorates Alzheimer's disease in HT22 cells by adjusting energy metabolism.
Dioscin attenuates Bleomycin-Induced acute lung injury via inhibiting the inflammatory response in mice.
Propentofylline reduces mechanical allodynia and induces mitogen-activated protein kinase phosphatase-1: An experimental study in a rat model of acute incisional pain.
PM2.5 upregulates rat mesenteric arteries 5-HT2A receptor via inflammatory-mediated mitogen-activated protein kinases signaling pathway.
MYCT1 represses apoptosis of laryngeal cancerous cells through the MAX/miR-181a/NPM1 pathway.
LncRNA ADPGK-AS1 regulated cell proliferation, invasion, migration and apoptosis via targeting miR-542-3p in osteosarcoma.
Berberine attenuates XRCC1-mediated base excision repair and sensitizes breast cancer cells to the chemotherapeutic drugs.
Glycine cleavage system determines the fate of pluripotent stem cells via the regulation of senescence and epigenetic modifications.
Cleavage and polyadenylation specific factor 4 promotes colon cancer progression by transcriptionally activating hTERT.
Apigenin reduces the excessive accumulation of lipids induced by palmitic acid via the AMPK signaling pathway in HepG2 cells.
The development of a cell-based model for the assessment of carcinogenic potential upon long-term PM2.5 exposure.
Inhibition of myeloid differentiation 1 specifically in colon with antisense oligonucleotide exacerbates dextran sodium sulfate-induced colitis.
RNA sequencing analysis of the CAL-27 cell response to over-expressed ZNF750 gene revealed an extensive regulation on cell cycle.
Limonin enhances the radiosensitivity of nasopharyngeal carcinoma cells via attenuating Stat3-induced cell stemness.
SIRT1 activation attenuates cardiac fibrosis by endothelial-to-mesenchymal transition.
Inhibition of high mobility group box 1 (HMGB1) attenuates podocyte apoptosis and epithelial-mesenchymal transition by regulating autophagy flux.
MiR-16a Regulates Milk Fat Metabolism by Targeting Large Tumor Suppressor Kinase 1 (LATS1) in Bovine Mammary Epithelial Cells.
Viral N6-methyladenosine upregulates replication and pathogenesis of human respiratory syncytial virus.
CircWHSC1 promotes ovarian cancer progression by regulating MUC1 and hTERT through sponging miR-145 and miR-1182.
Oxidative stress-induced cellular senescence desensitizes cell growth and migration of vascular smooth muscle cells through down-regulation of platelet-derived growth factor receptor-beta.
Tumor vasculature remolding by thalidomide increases delivery and efficacy of cisplatin.
Knockout of neutrophil elastase protects against western diet induced nonalcoholic steatohepatitis in mice by regulating hepatic ceramides metabolism.
SPOP suppresses pancreatic cancer progression by promoting the degradation of NANOG.
Circ-Spidr enhances axon regeneration after peripheral nerve injury.
γ-Oryzanol alleviates acetaminophen-induced liver injury: roles of modulating AMPK/GSK3β/Nrf2 and NF-κB signaling pathways.
Six1 is negatively correlated with poor prognosis and reduces 5-fluorouracil sensitivity via attenuating the stemness of hepatocellular carcinoma cells.
Angiotensin II deteriorates advanced atherosclerosis by promoting MerTK cleavage and impairing efferocytosis through the AT1R/ROS/p38 MAPK/ADAM17 pathway.
Melatonin Receptor Mel1b- and Mel1c-mediated Green Light Induced the Secretion of Growth Hormone in Anterior Pituitary of Chicks.
A novel RING finger protein CqRNF152-like with self-ubiquitination activity inhibits white spot syndrome virus infection in a crustacean Cherax quadricarinatus.
Zinc alleviates arsenism in common carp: Varied change profiles of cytokines and tight junction proteins among two intestinal segments.
Molecular cloning, expression and functional analysis of Atg16L1 from orange-spotted grouper (Epinephelus coioides).
Screening candidate microR-15a- IRAK2 regulatory pairs for predicting the response to Staphylococcus aureus-induced mastitis in dairy cows.
Tumor-suppressive activity of Hnf1β in Wilms' tumor.
The protective effects of L-carnitine on myocardial ischaemia-reperfusion injury in patients with rheumatic valvular heart disease undergoing CPB surgery are associated with the suppression of NF-κB pathway and the activation of Nrf2 pathway.
ADP-ribosyltransferase PARP11 modulates the interferon antiviral response by mono-ADP-ribosylating the ubiquitin E3 ligase β-TrCP.
Nonviral Delivery of GRIM-19 Gene Inhibits Tumor Growth with Reduced Local and Systemic Complications.
Long-term exposure of 4-hydroxyestradiol induces the cancer cell characteristics via upregulating CYP1B1 in MCF-10A cells.
Isoflurane produces antidepressant effects inducing BDNF-TrkB signaling in CUMS mice.
Astragaloside IV alleviates myocardial damage induced by type 2 diabetes via improving energy metabolism.
Deep Protein Methylation Profiling by Combined Chemical and Immunoaffinity Approaches Reveals Novel PRMT1 Targets.
Repurposing of the anti-helminthic drug niclosamide to treat melanoma and pulmonary metastasis via the STAT3 signaling pathway.
Increased Tim-3 expression alleviates liver injury by regulating macrophage activation in MCD-induced NASH mice.
LNRRIL6, a novel long noncoding RNA, protects colorectal cancer cells by activating the IL-6-STAT3 pathway.
Inhibition of p53 and/or AKT as a new therapeutic approach specifically targeting ALT cancers.
O-GlcNAcylation of Thr12/Ser56 in short-form O-GlcNAc transferase (sOGT) regulates its substrate selectivity.
LncRNA GABPB1-AS1 and GABPB1 regulate oxidative stress during erastin-induced ferroptosis in HepG2 hepatocellular carcinoma cells.
Porcine Circovirus Type 2 Induces Single Immunoglobulin Interleukin-1 Related Receptor (SIGIRR) Downregulation to Promote Interleukin-1β Upregulation in Porcine Alveolar Macrophage.
Dietary Stevioside Supplementation Alleviates Lipopolysaccharide-Induced Intestinal Mucosal Damage through Anti-Inflammatory and Antioxidant Effects in Broiler Chickens.
Mulberry leaf reduces inflammation and insulin resistance in type 2 diabetic mice by TLRs and insulin Signalling pathway.
Inhibition of PTP1B blocks pancreatic cancer progression by targeting the PKM2/AMPK/mTOC1 pathway.
Tissue plasminogen activator disrupts the blood-brain barrier through increasing the inflammatory response mediated by pericytes after cerebral ischemia.
Chitosan Oligosaccharide Attenuates Nonalcoholic Fatty Liver Disease Induced by High Fat Diet through Reducing Lipid Accumulation, Inflammation and Oxidative Stress in C57BL/6 Mice.
Cardioprotective effects of galectin-3 inhibition against ischemia/reperfusion injury.
Anti-osteoporosis effects of osteoking via reducing reactive oxygen species.
Epithelial and interstitial Notch1 activity contributes to the myofibroblastic phenotype and fibrosis.
Dengue Virus M Protein Promotes NLRP3 Inflammasome Activation To Induce Vascular Leakage in Mice.
Recombinant porcine NK-lysin inhibits the invasion of hepatocellular carcinoma cells in vitro.
Hepatocyte nuclear factor 1 alpha (HNF1A) regulates transcription of O-GlcNAc transferase in a negative feedback mechanism.
Degradation of Caytaxin Causes Learning and Memory Deficits via Activation of DAPK1 in Aging.
ZW290 Increases Cold Tolerance by Inducing Thermogenesis via the Upregulation of Uncoupling Protein 1 in Brown Adipose Tissue In Vitro and In Vivo.
Inhibition of PI3K/mTOR increased the sensitivity of hepatocellular carcinoma cells to cisplatin via interference with mitochondrial-lysosomal crosstalk.
Homeodomain-interacting protein kinase 2 suppresses proliferation and aerobic glycolysis via ERK/cMyc axis in pancreatic cancer.
Moderate- and Low-Dose of Atorvastatin Alleviate Cognition Impairment Induced by High-Fat Diet via Sirt1 Activation.
Apoptosis and cell cycle arrest of hepatocellular carcinoma spheroids treated by an alternating electric field.
[6]-Gingerol enhances the cisplatin sensitivity of gastric cancer cells through inhibition of proliferation and invasion via PI3K/AKT signaling pathway.
5-aminolevulinic acid photodynamic therapy reduces HPV viral load via autophagy and apoptosis by modulating Ras/Raf/MEK/ERK and PI3K/AKT pathways in HeLa cells.
A novel function of anaphase promoting complex subunit 10 in tumor progression in non-small cell lung cancer.
Nano hydroxyapatite induces glioma cell apoptosis by suppressing NF-κB signaling pathway.
Porcine circovirus type 2 ORF5 protein induces endoplasmic reticulum stress and unfolded protein response in porcine alveolar macrophages.
TDP-43 induces mitochondrial damage and activates the mitochondrial unfolded protein response.
Heat shock factor 1 in cancer-associated fibroblasts is a potential prognostic factor and drives progression of oral squamous cell carcinoma.
LncRNA TPT1-AS1 promotes tumorigenesis and metastasis in epithelial ovarian cancer by inducing TPT1 expression.
Highly Selective Protein Tyrosine Phosphatase Inhibitor, 2,2',3,3'-Tetrabromo-4,4',5,5'-tetrahydroxydiphenylmethane, Ameliorates Type 2 Diabetes Mellitus in BKS db Mice.
Adipose HuR protects against diet-induced obesity and insulin resistance.
Canagliflozin inhibits growth of hepatocellular carcinoma via blocking glucose-influx-induced β-catenin activation.
Fucoidan A2 from the Brown Seaweed Ascophyllum nodosum Lowers Lipid by Improving Reverse Cholesterol Transport in C57BL/6J Mice Fed a High-Fat Diet.
Estrogen negatively regulates the renal epithelial sodium channel (ENaC) by promoting Derlin-1 expression and AMPK activation.
Phosphatase of regenerating liver sensitizes MET to functional activation by hepatocyte growth factor.
Triptolide prevents proliferation and migration of Esophageal Squamous Cell Cancer via MAPK/ERK signaling pathway.
Comparison of the Hepatoprotective Effects of the Three Main Stilbenes from Mulberry Twigs.
MiR-34s negatively regulate homologous recombination through targeting RAD51.
Gambogic acid attenuates liver fibrosis by inhibiting the PI3K/AKT and MAPK signaling pathways via inhibiting HSP90.
Meningitic Escherichia coli-induced upregulation of PDGF-B and ICAM-1 aggravates blood-brain barrier disruption and neuroinflammatory response.
Sodium ferulate protects against influenza virus infection by activation of the TLR7/9-MyD88-IRF7 signaling pathway and inhibition of the NF-κB signaling pathway.
A maternal high-fat, high-sucrose diet induces transgenerational cardiac mitochondrial dysfunction independently of maternal mitochondrial inheritance.
Histone deacetylase 7 inhibits plakoglobin expression to promote lung cancer cell growth and metastasis.
Overexpression of ERBB4 rejuvenates aged mesenchymal stem cells and enhances angiogenesis via PI3K/AKT and MAPK/ERK pathways.
In utero exposure to PM2.5 during gestation caused adult cardiac hypertrophy through histone acetylation modification.
Nuciferine inhibits the progression of glioblastoma by suppressing the SOX2-AKT/STAT3-Slug signaling pathway.
Cysteine Dioxygenase Regulates the Epithelial Morphogenesis of Mammary Gland via Cysteine Sulfinic Acid.
Curcumin and Resveratrol Regulate Intestinal Bacteria and Alleviate Intestinal Inflammation in Weaned Piglets.
Effect of Stereochemical Configuration on the Transport and Metabolism of Catechins from Green Tea across Caco-2 Monolayers.
RNA-Binding Motif Protein 24 (RBM24) Is Involved in Pregenomic RNA Packaging by Mediating Interaction between Hepatitis B Virus Polymerase and the Epsilon Element.
GRASP depletion-mediated Golgi destruction decreases cell adhesion and migration via the reduction of α5β1 integrin.
The role of adenosine in up-regulation of p38 MAPK and ERK during limb ischemic preconditioning-induced brain ischemic tolerance.
Purification of cross-linked RNA-protein complexes by phenol-toluol extraction.
CD30 ligand deficiency accelerates glioma progression by promoting the formation of tumor immune microenvironment.
Deficiency of ZnT8 Promotes Adiposity and Metabolic Dysfunction by Increasing Peripheral Serotonin Production.
MicroRNA-145 regulates immune cytokines via targeting FSCN1 in Staphylococcus aureus-induced mastitis in dairy cows.
ERβ modulates genistein's cisplatin-enhancing activities in breast cancer MDA-MB-231 cells via P53-independent pathway.
p62 aggregates mediated Caspase 8 activation is responsible for progression of ovarian cancer.
Age-dependent expression of the vitamin D receptor and the protective effect of vitamin D receptor activation on H2O2-induced apoptosis in rat intervertebral disc cells.
TUSC3 as a potential biomarker for prognosis in clear cell renal cell carcinoma.
An NLRP3 inflammasome-triggered cytokine storm contributes to Streptococcal toxic shock-like syndrome (STSLS).
Decreased S1P and SPHK2 are involved in pancreatic acinar cell injury.
A promising therapeutic option for diabetic bladder dysfunction: Adipose tissue-derived stem cells pretreated by defocused low-energy shock wave.
Recombinant human arginase I elicited immunosuppression in activated macrophages through inhibiting autophagy.
Rh type C-glycoprotein functions as a novel tumor suppressor gene by inhibiting tumorigenicity and metastasis in head and neck squamous cell carcinoma.
Mechanism of Snhg8/miR-384/Hoxa13/FAM3A axis regulating neuronal apoptosis in ischemic mice model.
ROS/JNK/c-Jun axis is involved in oridonin-induced caspase-dependent apoptosis in human colorectal cancer cells.
TGF-β mediates thoracic radiation-induced abscopal effects of testis injury in rat.
Chitosan Hydrogel Delivery System Containing Herbal Compound Functions as a Potential Antineuroinflammatory Agent.
UHRF1 promotes aerobic glycolysis and proliferation via suppression of SIRT4 in pancreatic cancer.
TRIP4 promotes tumor growth and metastasis and regulates radiosensitivity of cervical cancer by activating MAPK, PI3K/AKT, and hTERT signaling.
Silencing of Aberrant Secretory Protein Expression by Disease-Associated Mutations.
Organophosphorus Flame Retardants Impair Intracellular Lipid Metabolic Function in Human Hepatocellular Cells.
Blocking podoplanin suppresses growth and pulmonary metastasis of human malignant melanoma.
Insulin transcriptionally down-regulates carboxylesterases through pregnane X receptor in an Akt-dependent manner.
Inhibition of Glioma Development by ASCL1-Mediated Direct Neuronal Reprogramming.
Porcine HMGCR Inhibits Porcine Circovirus Type 2 Infection by Directly Interacting with the Viral Proteins.
Sonodynamic therapy inhibits palmitate-induced beta cell dysfunction via PINK1/Parkin-dependent mitophagy.
Macrophage Migration Inhibitory Factor Promotes Chemotaxis of Astrocytes through Regulation of Cholesterol 25-Hydroxylase Following Rat Spinal Cord Injury.
A new split-luciferase complementation assay identifies pentachlorophenol as an inhibitor of apoptosome formation.
Activation of the immunoproteasome protects SH-SY5Y cells from the toxicity of rotenone.
Atractylodin ameliorates lipopolysaccharide and d-galactosamine-induced acute liver failure via the suppression of inflammation and oxidative stress.
MicroRNA-221 sensitizes chronic myeloid leukemia cells to imatinib by targeting STAT5.
Epithelial ovarian cancer stem‑like cells are resistant to the cellular lysis of cytokine‑induced killer cells via HIF1A‑mediated downregulation of ICAM‑1.
Aspirin targets P4HA2 through inhibiting NF-κB and LMCD1-AS1/let-7g to inhibit tumour growth and collagen deposition in hepatocellular carcinoma.
Tubeimoside-1, a triterpenoid saponin, induces cytoprotective autophagy in human breast cancer cells in vitro via Akt-mediated pathway.
Septin 9 isoforms promote tumorigenesis in mammary epithelial cells by increasing migration and ECM degradation through metalloproteinase secretion at focal adhesions.
STAT3 phosphorylation mediates high glucose-impaired cell autophagy in an HDAC1-dependent and -independent manner in Schwann cells of diabetic peripheral neuropathy.
Notch signaling activation induces cell death in MAPKi-resistant melanoma cells.
Complement C3 activation regulates the production of tRNA-derived fragments Gly-tRFs and promotes alcohol-induced liver injury and steatosis.
CtIP promotes G2/M arrest in etoposide-treated HCT116 cells in a p53-independent manner.
DAAM1-mediated migration and invasion of ovarian cancer cells are suppressed by miR-208a-5p.
Harnessing the anti-cancer natural product nimbolide for targeted protein degradation.
Observation of novel COX20 mutations related to autosomal recessive axonal neuropathy and static encephalopathy.
Low-dose PCB126 compromises circadian rhythms associated with disordered glucose and lipid metabolism in mice.
UCP2 alleviates tubular epithelial cell apoptosis in lipopolysaccharide-induced acute kidney injury by decreasing ROS production.
Roscovitine attenuates renal interstitial fibrosis in diabetic mice through the TGF-β1/p38 MAPK pathway.
Naringenin ameliorates insulin resistance by modulating endoplasmic reticulum stress in hepatitis C virus-infected liver.
Regulation of CD11b by HIF-1α and the STAT3 signaling pathway contributes to the immunosuppressive function of B cells in inflammatory bowel disease.
Lysine glutarylation in human sperm is associated with progressive motility.
Inhibition of nucleotide synthesis promotes replicative senescence of human mammary epithelial cells.
A novel hydrogen sulfide-releasing donor, HA-ADT, suppresses the growth of human breast cancer cells through inhibiting the PI3K/AKT/mTOR and Ras/Raf/MEK/ERK signaling pathways.
Lingguizhugan decoction attenuates diet-induced obesity and hepatosteatosis via gut microbiota.
Hypoxia inducible factor 1α in vascular smooth muscle cells promotes angiotensin II-induced vascular remodeling via activation of CCL7-mediated macrophage recruitment.
AcMNPV PKIP is associated with nucleocapsid of budded virions and involved in nucleocapsid assembly.
CUL7 E3 Ubiquitin Ligase Mediates the Degradation of Activation-Induced Cytidine Deaminase and Regulates the Ig Class Switch Recombination in B Lymphocytes.
Tri-ortho-cresyl phosphate (TOCP) induced ovarian failure in mice is related to the Hippo signaling pathway disruption.
Autocrine secretions enhance radioresistance in an exosome‑independent manner in NSCLC cells.
miR-132-3p boosts caveolae-mediated transcellular transport in glioma endothelial cells by targeting PTEN/PI3K/PKB/Src/Cav-1 signaling pathway.
Plant-derived alkaloid sinomenine potentiates glucocorticoid pharmacodynamics in mitogen-activated human peripheral blood mononuclear cells by regulating the translocation of glucocorticoid receptor.
MMP-9 Upregulation is Attenuated by the Monoclonal TLR2 Antagonist T2.5 After Oxygen-Glucose Deprivation and Reoxygenation in Rat Brain Microvascular Endothelial Cells.
Function of BRD4 in the pathogenesis of high glucose‑induced cardiac hypertrophy.
SVIP alleviates CCl4-induced liver fibrosis via activating autophagy and protecting hepatocytes.
LncRNA SNHG12 inhibits miR-199a to upregulate SIRT1 to attenuate cerebral ischemia/reperfusion injury through activating AMPK signaling pathway.
Reciprocal regulation of integrin β4 and KLF4 promotes gliomagenesis through maintaining cancer stem cell traits.
MMP13 inhibition rescues cognitive decline in Alzheimer transgenic mice via BACE1 regulation.
Mechanism underlying the retarded nuclear translocation of androgen receptor splice variants.
Sodium rutin ameliorates Alzheimer's disease-like pathology by enhancing microglial amyloid-β clearance.
Nucleoporin 107 facilitates the nuclear export of Scn5a mRNA to regulate cardiac bioelectricity.
Effects of Fluoride on Autophagy in Mouse Sertoli Cells.
CDK11p110 plays a critical role in the tumorigenicity of esophageal squamous cell carcinoma cells and is a potential drug target.
Intestinal non-canonical NFκB signaling shapes the local and systemic immune response.
Dietary canolol induces apoptosis in human cervical carcinoma HeLa cells through ROS-MAPK mediated mitochondrial signaling pathway: In vitro and in vivo.
Kibra Modulates Learning and Memory via Binding to Dendrin.
miR-33 and RIP140 participate in LPS-induced acute lung injury
Gene expression profile-based drug screen identifies SAHA as a novel treatment for NAFLD.
The Autographa californica Multiple Nucleopolyhedrovirus ac51 Gene Is Required for Efficient Nuclear Egress of Nucleocapsids and Is Essential for In Vivo Virulence.
SRT1720 retards renal fibrosis via inhibition of HIF1α /GLUT1 in diabetic nephropathy.
JAK2/STAT1-mediated HMGB1 translocation increases inflammation and cell death in a ventilator-induced lung injury model.
LncRNA SNHG4 promotes the proliferation, migration, invasiveness, and epithelial-mesenchymal transition of lung cancer cells by regulating miR-98-5p.
NO donor inhibits proliferation and induces apoptosis by targeting PI3K/AKT/mTOR and MEK/ERK pathways in hepatocellular carcinoma cells.
Carpesium abrotanoides (L.) Root as a Potential Source of Natural Anticancer Compounds: Targeting Glucose Metabolism and PKM2/HIF-1α Axis of Breast Cancer Cells.
Indoxyl sulfate-induced calcification of vascular smooth muscle cells via the PI3K/Akt/NF-κB signaling pathway.
Peroxisome Proliferator-Activated Receptors (PPARs) levels in spermatozoa of normozoospermic and asthenozoospermic men.
LncRNA-241 inhibits 1,2-Dichloroethane-induced hepatic apoptosis.
Lipopolysaccharide-induced DNA damage response activates nuclear factor κB signalling pathway via GATA4 in dental pulp cells.
Transcriptome sequencing of Eospalax fontanierii to determine hypoxia regulation of cardiac fibrinogen.
Dysregulated Transcription Factor TFAP2A After Peripheral Nerve Injury Modulated Schwann Cell Phenotype.
ORP4L couples IP3 to ITPR1 in control of endoplasmic reticulum calcium release.
Base pair editing in goat: nonsense codon introgression into FGF5 results in longer hair.
Rotenone protects against β-cell apoptosis and attenuates type 1 diabetes mellitus.
S100A9 regulates porcine reproductive and respiratory syndrome virus replication by interacting with the viral nucleocapsid protein.
Tandem repeat sequence of duck circovirus serves as downstream sequence element to regulate viral gene expression.
miR-451a inhibits cancer growth, epithelial-mesenchymal transition and induces apoptosis in papillary thyroid cancer by targeting PSMB8.
Punicalagin Reversed the Hepatic Injury of Tetrachloromethane by Antioxidation and Enhancement of Autophagy.
Hypoxia enhances IL-10-producing B cell generation through upregulating high-mobility group B1 on tumor cell-released autophagosomes.
Novel sphingomyelin biomarkers for brain glioma and associated regulation research on the PI3K/Akt signaling pathway.
Catalpol alleviates adriamycin-induced nephropathy by activating the SIRT1 signalling pathway in vivo and in vitro.
HDAC11 restricts HBV replication through epigenetic repression of cccDNA transcription.
BECN1 promotes the migration of NSCLC cells through regulating the ubiquitination of Vimentin.
Xiaoerfupi alleviates the symptoms of functional dyspepsia by regulating the HTR3A and c-FOS.
Pleiotropic Effects of Epithelial Mesenchymal Crosstalk on Head and Neck Cancer: EMT and beyond.
Endocytic degradation of ErbB2 mediates the effectiveness of neratinib in the suppression of ErbB2-positive ovarian cancer.
Curcumin inhibits LPS-induced neuroinflammation by promoting microglial M2 polarization via TREM2/ TLR4/ NF-κB pathways in BV2 cells.
Critical roles of NLRP3 inflammasome in IL-1β secretion induced by Corynebacterium pseudotuberculosis in vitro.
Activating macrophages for enhanced osteogenic and bactericidal performance by Cu ion release from micro/nano-topographical coating on a titanium substrate.
Oral Administration of Succinoglycan Riclin Improves Diet-Induced Hypercholesterolemia in Mice.
Yes-associated protein regulates podocyte cell cycle re-entry and dedifferentiation in adriamycin-induced nephropathy.
Sal B Alleviates Myocardial Ischemic Injury by Inhibiting TLR4 and the Priming Phase of NLRP3 Inflammasome.
Hydrogen sulfide attenuates mitochondrial dysfunction-induced cellular senescence and apoptosis in alveolar epithelial cells by upregulating sirtuin 1.
Beneficial Effects of Ticagrelor on Oxidized Low-Density Lipoprotein (ox-LDL)-Induced Apoptosis in Human Umbilical Vein Endothelial Cells.
RASAL1 induces to downregulate the SCD1, leading to suppression of cell proliferation in colon cancer via LXRα/SREBP1c pathway.
Stasimon Contributes to the Loss of Sensory Synapses and Motor Neuron Death in a Mouse Model of Spinal Muscular Atrophy.
Gdf11 gene transfer prevents high fat diet-induced obesity and improves metabolic homeostasis in obese and STZ-induced diabetic mice.
Integration of transcriptomics and network analysis deciphers the mechanisms of baicalein in improving learning and memory impairment in senescence-accelerated mouse prone 8 (SAMP8).
Rafoxanide promotes apoptosis and autophagy of gastric cancer cells by suppressing PI3K /Akt/mTOR pathway.
PI3K/Akt inhibitor partly decreases TNF-α-induced activation of fibroblast-like synoviocytes in osteoarthritis.
Aptamer-Based Erythrocyte-Derived Mimic Vesicles Loaded with siRNA and Doxorubicin for the Targeted Treatment of Multidrug-Resistant Tumors.
7-O-geranylquercetin contributes to reverse P-gp-mediated adriamycin resistance in breast cancer.
Fe3O4@OA@Poloxamer nanoparticles lower triglyceride in hepatocytes through liposuction effect and nano-enzyme effect.
Abnormal expression of Pappa2 gene may indirectly affect mouse hip development through the IGF signaling pathway.
MIF/CD74 axis participates in inflammatory activation of Schwann cells following sciatic nerve injury.
In Vitro Infectious Risk Assessment of Heliothis virescens ascovirus 3j (HvAV-3j) toward Non-target Vertebrate Cells.
PLZF regulates apoptosis of leukemia cells by regulating AKT/Foxo3a pathway.
The effects of fluorene-9-bisphenol on female zebrafish (Danio rerio) reproductive and exploratory behaviors.
17β‑Estradiol protects against interleukin‑1β‑induced apoptosis in rat nucleus pulposus cells via the mTOR/caspase‑3 pathway.
Proteomic Analysis Reveals that Odoroside A Triggers G2/M Arrest and Apoptosis in Colorectal Carcinoma Through ROS-p53 Pathway.
Diosgenin regulates cholesterol metabolism in hypercholesterolemic rats by inhibiting NPC1L1 and enhancing ABCG5 and ABCG8.
HSF1 phosphorylation by cyclosporin A confers hyperthermia sensitivity through suppression of HSP expression.
Sesterterpene MHO7 suppresses breast cancer cells as a novel estrogen receptor degrader.
Proteomic analysis of murine bone marrow derived dendritic cells in response to peste des petits ruminants virus.
Involvement of microRNA-23b-5p in the promotion of cardiac hypertrophy and dysfunction via the HMGB2 signaling pathway.
Interleukin-1 receptor associated kinase (IRAK)-M -mediated type 2 microglia polarization ameliorates the severity of experimental autoimmune encephalomyelitis (EAE).
USP49 potently stabilizes APOBEC3G protein by removing ubiquitin and inhibits HIV-1 replication.
Bone marrow-derived mesenchymal stromal cells promote resistance to tyrosine kinase inhibitors in chronic myeloid leukemia via the IL-7/JAK1/STAT5 pathway.
Stimulation of endothelial progenitor cells by microRNA-31a-5p to induce endothelialization in an aneurysm neck after coil embolization by modulating the Axin1-mediated β-catenin/vascular endothelial growth factor pathway.
ANLN-induced EZH2 upregulation promotes pancreatic cancer progression by mediating miR-218-5p/LASP1 signaling axis.
Jingfukang induces anti-cancer activity through oxidative stress-mediated DNA damage in circulating human lung cancer cells.
Platelet-Membrane-Camouflaged Black Phosphorus Quantum Dots Enhance Anticancer Effect Mediated by Apoptosis and Autophagy.
Epigenetic Memory Is Involved in the Persistent Alterations of Drug-Processing Genes in Adult Mice due to PCN-Activated PXR during Early Life.
Large-conductance calcium-activated potassium channels mediate lipopolysaccharide-induced activation of murine microglia.
ORMDL3 knockdown in the lungs alleviates airway inflammation and airway remodeling in asthmatic mice via JNK1/2-MMP-9 pathway.
Glial response in early stages of traumatic brain injury.
Divergent engagements between adeno-associated viruses with their cellular receptor AAVR.
BMAL1 Disrupted Intrinsic Diurnal Oscillation in Rat Cerebrovascular Contractility of Simulated Microgravity Rats by Altering Circadian Regulation of miR-103/CaV1.2 Signal Pathway.
Induction of Fibroblast Senescence During Mouse Corneal Wound Healing.
The fucoidan A3 from the seaweed Ascophyllum nodosum enhances RCT-related genes expression in hyperlipidemic C57BL/6J mice.
The fucoidan from the brown seaweed Ascophyllum nodosum ameliorates atherosclerosis in apolipoprotein E-deficient mice.
The status of ω-3 PUFAs influence chronic unpredicted mild stress-induced metabolic side effects in rats through INSIG/SREBP pathway.
LncRNA THOR increases osteosarcoma cell stemness and migration by enhancing SOX9 mRNA stability.
Nerve growth factor prevents arsenic-induced toxicity in PC12 cells through the AKT/GSK-3β/NFAT pathway.
NLRP3 inflammasome plays an important role in caspase-1 activation and IL-1β secretion in macrophages infected with Pasteurella multocida.
Curcumin exerts cytotoxicity dependent on reactive oxygen species accumulation in non-small-cell lung cancer cells.
Downregulation of RGMA by HIF-1A/miR-210-3p axis promotes cell proliferation in oral squamous cell carcinoma.
Aspirin ameliorates lung cancer by targeting the miR-98/WNT1 axis.
Human cells are permissive for the productive infection of porcine circovirus type 2 in vitro.
LncRNA SNHG20 predicts a poor prognosis and promotes cell progression in epithelial ovarian cancer.
UBE2C functions as a potential oncogene by enhancing cell proliferation, migration, invasion, and drug resistance in hepatocellular carcinoma cells.
Excessive miR-25-3p maturation via N6-methyladenosine stimulated by cigarette smoke promotes pancreatic cancer progression.
Icariin attenuates neuroinflammation and exerts dopamine neuroprotection via an Nrf2-dependent manner.
Ntrk1 Promotes Resistance to PD-1 Checkpoint Blockade in Mesenchymal Kras/p53 Mutant Lung Cancer.
Macrophage migration inhibitory factor facilitates prostaglandin E2 production of astrocytes to tune inflammatory milieu following spinal cord injury.
MicroRNA-106b Regulates Milk Fat Metabolism via ATP Binding Cassette Subfamily A Member 1 ( ABCA1) in Bovine Mammary Epithelial Cells.
Immunomodulatory effects of an acidic polysaccharide fraction from herbal Gynostemma pentaphyllum tea in RAW264.7 cells.
Exosomal ephrinA2 derived from serum as a potential biomarker for prostate cancer.
AMPH-1 is critical for breast cancer progression.
The Protective Effect of Astaxanthin on Cognitive Function via Inhibition of Oxidative Stress and Inflammation in the Brains of Chronic T2DM Rats.
Maternal Protein Restriction Induces Alterations in Hepatic Unfolded Protein Response-Related Molecules in Adult Rat Offspring.
β-TrCP Restricts Lipopolysaccharide (LPS)-Induced Activation of TRAF6-IKK Pathway Upstream of IκBα Signaling.
The Host Restriction Factor Interferon-Inducible Transmembrane Protein 3 Inhibits Vaccinia Virus Infection.
Protective Effect of Extract of Bletilla Striata on Isoflurane Induced Neuronal Injury By Altering PI3K/Akt Pathway.
Magnolol Alleviates Inflammatory Responses and Lipid Accumulation by AMP-Activated Protein Kinase-Dependent Peroxisome Proliferator-Activated Receptor α Activation.
Geniposide and Chlorogenic Acid Combination Ameliorates Non-alcoholic Steatohepatitis Involving the Protection on the Gut Barrier Function in Mouse Induced by High-Fat Diet.
Oncolytic Newcastle disease virus induces autophagy-dependent immunogenic cell death in lung cancer cells.
Add-On therapy with Chinese herb medicine Bo-Er-Ning capsule (BENC) improves outcomes of gastric cancer patients: a randomized clinical trial followed with bioinformatics-assisted mechanism study.
Liposomal Curcumin Targeting Endometrial Cancer Through the NF-κB Pathway.
Placental growth factor promotes epithelial-mesenchymal transition-like changes in ARPE-19 cells under hypoxia.
Dorsal Root Ganglion Maintains Stemness of Bone Marrow Mesenchymal Stem Cells by Enhancing Autophagy through the AMPK/mTOR Pathway in a Coculture System.
Glucagon-Like Peptide-1 Mediates the Protective Effect of the Dipeptidyl Peptidase IV Inhibitor on Renal Fibrosis via Reducing the Phenotypic Conversion of Renal Microvascular Cells in Monocrotaline-Treated Rats.
Oxidative stress and NF-κB signaling are involved in LPS induced pulmonary dysplasia in chick embryos.
Foot-and-mouth disease virus capsid protein VP2 activates the cellular EIF2S1-ATF4 pathway and induces autophagy via HSPB1.
TRIM59 regulates autophagy through modulating both the transcription and the ubiquitination of BECN1.
Linagliptin unmasks specific antioxidant pathways protective against albuminuria and kidney hypertrophy in a mouse model of diabetes.
Dysregulation of Neuregulin-1/ErbB signaling in the hippocampus of rats after administration of doxorubicin.
Involvement of microRNA-146a in diabetic peripheral neuropathy through the regulation of inflammation.
Expression and significance of the Hedgehog signal transduction pathway in oxygen-induced retinal neovascularization in mice.
miR-222-3p promotes osteosarcoma cell migration and invasion through targeting TIMP3.
Protective Effect of Hydrogen on Sodium Iodate-Induced Age-Related Macular Degeneration in Mice.
Dl-3-n-Butylphthalide improves lipopolysaccharide-induced depressive-like behavior in rats: involvement of Nrf2 and NF-κB pathways.
miR-34b-5p inhibition attenuates lung inflammation and apoptosis in an LPS-induced acute lung injury mouse model by targeting progranulin.
Amyotrophic lateral sclerosis (ALS) and Alzheimer's disease (AD) are characterised by differential activation of ER stress pathways: focus on UPR target genes.
Exosomal zinc transporter ZIP4 promotes cancer growth and is a novel diagnostic biomarker for pancreatic cancer.
Disruption of Tmem30a results in cerebellar ataxia and degeneration of Purkinje cells.
The regulatory effects of metformin on the [SNAIL/miR-34]:[ZEB/miR-200] system in the epithelial-mesenchymal transition(EMT) for colorectal cancer(CRC).
Targeting Epigenetic Crosstalk as a Therapeutic Strategy for EZH2-Aberrant Solid Tumors.
Transcriptomic but not genomic variability confers phenotype of breast cancer stem cells.
Cattle Encephalon Glycoside and Ignotin Reduce Early Brain Injury and Cognitive Dysfunction after Subarachnoid Hemorrhage in Rats.
Cutting Edge: Dysregulated CARD9 Signaling in Neutrophils Drives Inflammation in a Mouse Model of Neutrophilic Dermatoses.
Resveratrol Suppresses Matrix Metalloproteinase-2 Activation Induced by Lipopolysaccharide in Mouse Osteoblasts via Interactions with AMP-Activated Protein Kinase and Suppressor of Cytokine Signaling 1.
The apoptosis in arsenic-induced oxidative stress is associated with autophagy in the testis tissues of chicken.
Dipeptidyl peptidase IV (DPP-4) inhibition alleviates pulmonary arterial remodeling in experimental pulmonary hypertension.
Bone morphogenetic protein 4 expression in the developing lumbosacral spinal cord of rat embryos with anorectal malformations.
MicroRNA-543 functions as an osteogenesis promoter in human periodontal ligament-derived stem cells by inhibiting transducer of ERBB2, 2.
Curcumol induces RIPK1/RIPK3 complex-dependent necroptosis via JNK1/2-ROS signaling in hepatic stellate cells.
Quantitative Global Proteome and Lysine Succinylome Analyses Reveal the Effects of Energy Metabolism in Renal Cell Carcinoma.
Salidroside attenuates endothelial cellular senescence via decreasing the expression of inflammatory cytokines and increasing the expression of SIRT3.
TRIM65 supports bladder urothelial carcinoma cell aggressiveness by promoting ANXA2 ubiquitination and degradation.
Cyclophilin J limits inflammation through the blockage of ubiquitin chain sensing.
Berberrubine and its analog, hydroxypropyl-berberrubine, regulate LDLR and PCSK9 expression via the ERK signal pathway to exert cholesterol-lowering effects in human hepatoma HepG2 cells.
Apelin-13 Upregulates BDNF Against Chronic Stress-induced Depression-like Phenotypes by Ameliorating HPA Axis and Hippocampal Glucocorticoid Receptor Dysfunctions.
Reduced graphene oxide triggered epithelial-mesenchymal transition in A549 cells.
Andrographolide inhibits breast cancer through suppressing COX-2 expression and angiogenesis via inactivation of p300 signaling and VEGF pathway.
SUMO-1 modification of FEN1 facilitates its interaction with Rad9-Rad1-Hus1 to counteract DNA replication stress.
Fluoride induces apoptosis and autophagy through the IL-17 signaling pathway in mice hepatocytes.
Atorvastatin Pretreatment Attenuates Ischemic Brain Edema by Suppressing Aquaporin 4.
Oncogenic activation of PI3K induces progenitor cell differentiation to suppress epidermal growth.
(2R,3R)Dihydromyricetin inhibits osteoclastogenesis and bone loss through scavenging LPS-induced oxidative stress and NF-κB and MAPKs pathways activating.
NR2B-Tyr phosphorylation regulates synaptic plasticity in central sensitization in a chronic migraine rat model.
MicroRNA-32 Regulates Development and Progression of Hepatocellular Carcinoma by Targeting ADAMTS9 and Affects Its Prognosis.
Zinc finger E-box-binding homeobox 1 mediates aerobic glycolysis via suppression of sirtuin 3 in pancreatic cancer.
Estrogen receptor β upregulated by lncRNA-H19 to promote cancer stem-like properties in papillary thyroid carcinoma.
Citrus Tangeretin Improves Skeletal Muscle Mitochondrial Biogenesis via Activating the AMPK-PGC1-α Pathway In Vitro and In Vivo: A Possible Mechanism for Its Beneficial Effect on Physical Performance.
Nitric oxide triggers the assembly of "type II" stress granules linked to decreased cell viability.
Inhibitor of Bruton's tyrosine kinases, PCI-32765, decreases pro-inflammatory mediators' production in high glucose-induced macrophages.
Overexpression of collagen type V α1 chain in human breast invasive ductal carcinoma is mediated by TGF-β1.
Establishment of a human embryonic stem cell line with homozygous TP53 R248W mutant by TALEN mediated gene editing.
Induction of OTUD1 by RNA viruses potently inhibits innate immune responses by promoting degradation of the MAVS/TRAF3/TRAF6 signalosome.
Systemic administration of scAAV9-IGF1 extends survival in SOD1G93A ALS mice via inhibiting p38 MAPK and the JNK-mediated apoptosis pathway.
Exogenous leptin affects sperm parameters and impairs blood testis barrier integrity in adult male mice.
IRF8 Regulates Transcription of Naips for NLRC4 Inflammasome Activation.
Effect of propolis on preserving human periodontal ligament cells and regulating pro-inflammatory cytokines.
Hepatoprotection of auraptene from peels of citrus fruits against thioacetamide-induced hepatic fibrosis in mice by activating farnesoid X receptor.
TRIM50 suppressed hepatocarcinoma progression through directly targeting SNAIL for ubiquitous degradation.
Renal protective effect of Paeoniflorin by inhibition of JAK2/STAT3 signaling pathway in diabetic mice.
Cell Cycle Regulation by Alternative Polyadenylation of CCND1.
Dietary α-Mangostin Provides Protective Effects against Acetaminophen-Induced Hepatotoxicity in Mice via Akt/mTOR-Mediated Inhibition of Autophagy and Apoptosis.
ASK1/2 signaling promotes inflammation in a mouse model of neutrophilic dermatosis.
Innately activated TLR4 signal in the nucleus accumbens is sustained by CRF amplification loop and regulates impulsivity.
Effects of gelling bath on the physical properties of alginate gel beads and the biological characteristics of entrapped HepG2 cells.
Insulin Treatment Cannot Promote Lipogenesis in Rat Fetal Lung in Gestational Diabetes Mellitus Because of Failure to Redress the Imbalance Among SREBP-1, SCAP, and INSIG-1.
Ubenimex, an APN inhibitor, could serve as an anti‑tumor drug in RT112 and 5637 cells by operating in an Akt‑associated manner.
LIFR increases the release of soluble endoglin via the upregulation of MMP14 expression in preeclampsia.
7α,8α-Epoxynagilactones and their glucosides from the twigs of Podocarpus nagi: Isolation, structures, and cytotoxic activities.
Nicotine-Induced Neuroprotection against Cognitive Dysfunction after Partial Hepatectomy Involves Activation of BDNF/TrkB Signaling Pathway and Inhibition of NF-κB Signaling Pathway in Aged Rats.
Effect of Di-(2-ethylhexyl) phthalate on the hypothalamus-pituitary-thyroid axis in adolescent rat.
Exosomes from C2C12 myoblasts enhance osteogenic differentiation of MC3T3-E1 pre-osteoblasts by delivering miR-27a-3p.
New Drug Candidate Targeting the 4A1 Orphan Nuclear Receptor for Medullary Thyroid Cancer Therapy.
Apoptosome formation upon overexpression of native and truncated Apaf-1 in cell-free and cell-based systems.
Mitochondrial Dysfunctions Contribute to Hypertrophic Cardiomyopathy in Patient iPSC-Derived Cardiomyocytes with MT-RNR2 Mutation.
Cell division cycle 7 is a potential therapeutic target in oral squamous cell carcinoma and is regulated by E2F1.
IL-6 receptor blockade ameliorates diabetic nephropathy via inhibiting inflammasome in mice.
Metformin inhibits ovarian cancer via decreasing H3K27 trimethylation.
Avian leukosis virus subgroup J promotes cell proliferation and cell cycle progression through miR-221 by targeting CDKN1B.
PEDF improves cardiac function in rats subjected to myocardial ischemia/reperfusion injury by inhibiting ROS generation via PEDF‑R.
Effect of Banxia Xiexin decoction on Helicobacter pylori-related peptic ulcers and its possible mechanism via the TGF-β/Smad signaling pathway.
Doxycycline attenuates chronic intermittent hypoxia-induced atrial fibrosis in rats.
Cysteine-rich protein 61 regulates adipocyte differentiation from mesenchymal stem cells through mammalian target of rapamycin complex 1 and canonical Wnt signaling.
A comparison of CRISPR/Cas9 and siRNA-mediated ALDH2 gene silencing in human cell lines.
Effects of nicotine on the metabolism and gene expression profile of Sprague‑Dawley rat primary osteoblasts.
Myxovirus resistance protein A inhibits hepatitis C virus replication through JAK-STAT pathway activation.
Berberine exerts antioxidant effects via protection of spiral ganglion cells against cytomegalovirus-induced apoptosis.
Tert-butylhydroquinone post-treatment attenuates neonatal hypoxic-ischemic brain damage in rats.
Enhancer of zeste homolog 2 promotes cisplatin resistance by reducing cellular platinum accumulation.
Effects of Levonorgestrel and progesterone on Oviductal physiology in mammals.
Alpha protocadherins and Pyk2 kinase regulate cortical neuron migration and cytoskeletal dynamics via Rac1 GTPase and WAVE complex in mice.
DRm217 attenuates myocardial ischemia-reperfusion injury via stabilizing plasma membrane Na+-K+-ATPase, inhibiting Na+-K+-ATPase/ROS pathway and activating PI3K/Akt and ERK1/2.
Long noncoding RNA lncARSR promotes hepatic cholesterol biosynthesis via modulating Akt/SREBP-2/HMGCR pathway.
Acetylation of oxidized base repair-initiating NEIL1 DNA glycosylase required for chromatin-bound repair complex formation in the human genome increases cellular resistance to oxidative stress.
Underexpression of Receptor for Activated C Kinase 1 (RACK1) in Leukocytes from Patients with Severe Acute Pancreatitis.
Generation and propagation of yeast prion [URE3] are elevated under electromagnetic field.
Japanese encephalitis virus induces apoptosis by inhibiting Foxo signaling pathway.
Membrane topology of rat sodium-coupled neutral amino acid transporter 2 (SNAT2).
Rapamycin and ZSTK474 can have differential effects at different post‑infection time‑points regarding CVB3 replication and CVB3‑induced autophagy.
Chronic stress causes protein kinase C epsilon-aldehyde dehydrogenase 2 signaling pathway perturbation in the rat hippocampus and prefrontal cortex, but not in the myocardium.
A Polysaccharide Isolated from Dictyophora indusiata Promotes Recovery from Antibiotic-Driven Intestinal Dysbiosis and Improves Gut Epithelial Barrier Function in a Mouse Model.
The actin cytoskeletal architecture of estrogen receptor positive breast cancer cells suppresses invasion.
Myc activity is required for maintenance of the neuromesodermal progenitor signalling network and for segmentation clock gene oscillations in mouse.
Synthesis and structure-activity relationship studies of MI-2 analogues as MALT1 inhibitors.
Vitamin C increases 5-hydroxymethylcytosine level and inhibits the growth of bladder cancer.
A novel small-molecule activator of Sirtuin-1 induces autophagic cell death/mitophagy as a potential therapeutic strategy in glioblastoma.
A reproducible swine model of proximal descending thoracic aortic aneurysm created with intra-adventitial application of elastase.
Photobiomodulation therapy promotes neurogenesis by improving post-stroke local microenvironment and stimulating neuroprogenitor cells.
Hypoxia induces the dysfunction of human endothelial colony-forming cells via HIF-1α signaling.
Mechanism of prolactin inhibition of miR-135b via methylation in goat mammary epithelial cells.
Selectivity, cell permeability and oral availability studies of novel bromophenol derivative HPN as protein tyrosine phosphatase 1B inhibitor.
Clinical efficacy of recombinant human latrophilin 3 antibody in the treatment of pediatric asthma.
PTEN-L promotes type I interferon responses and antiviral immunity.
Epithelial-mesenchymal crosstalk induces radioresistance in HNSCC cells.
Wnt/β-catenin pathway promotes acute lung injury induced by LPS through driving the Th17 response in mice.
Comparative Proteomics Analysis Identifies Cdc42-Cdc42BPA Signaling as Prognostic Biomarker and Therapeutic Target for Colon Cancer Invasion.
Rhubarb Supplementation Promotes Intestinal Mucosal Innate Immune Homeostasis through Modulating Intestinal Epithelial Microbiota in Goat Kids.
Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral β-lactam bridged combretastatin A-4 analogues as potent antitumor agents.
SOCE induced calcium overload regulates autophagy in acute pancreatitis via calcineurin activation.
Autophagy promotes metastasis and glycolysis by upregulating MCT1 expression and Wnt/β-catenin signaling pathway activation in hepatocellular carcinoma cells.
Proteasome Inhibitor Carbobenzoxy-L-Leucyl-L-Leucyl-L-Leucinal (MG132) Enhances Therapeutic Effect of Paclitaxel on Breast Cancer by Inhibiting Nuclear Factor (NF)-κB Signaling.
miR-3189-3p Mimics Enhance the Effects of S100A4 siRNA on the Inhibition of Proliferation and Migration of Gastric Cancer Cells by Targeting CFL2.
Uncovering the anticancer mechanism of Compound Kushen Injection against HCC by integrating quantitative analysis, network analysis and experimental validation.
Dietary Supplement of Large Yellow Tea Ameliorates Metabolic Syndrome and Attenuates Hepatic Steatosis in db/db Mice.
Repulsive guidance molecule a suppresses angiogenesis after ischemia/reperfusion injury of middle cerebral artery occlusion in rats.
Protein Kinase A/CREB Signaling Prevents Adriamycin-Induced Podocyte Apoptosis via Upregulation of Mitochondrial Respiratory Chain Complexes.
Eukaryotic translation initiation factor 2 subunit α (eIF2α) inhibitor salubrinal attenuates paraquat-induced human lung epithelial-like A549 cell apoptosis by regulating the PERK-eIF2α signaling pathway.
RhPDCD5 combined with dexamethasone increases antitumor activity in multiple myeloma partially via inhibiting the Wnt signalling pathway.
Aberrant expression of miR-451a contributes to 1,2-dichloroethane-induced hepatic glycerol gluconeogenesis disorder by inhibiting glycerol kinase expression in NIH Swiss mice.
Ephrin receptor A2 is an epithelial cell receptor for Epstein-Barr virus entry.
Carnosol-mediated Sirtuin 1 activation inhibits Enhancer of Zeste Homolog 2 to attenuate liver fibrosis.
N-oleoylethanolamide suppresses intimal hyperplasia after balloon injury in rats through AMPK/PPARα pathway.
PUM1 promotes ovarian cancer proliferation, migration and invasion.
Interferon-alpha enhances the antitumour activity of EGFR-targeted therapies by upregulating RIG-I in head and neck squamous cell carcinoma.
Involvement of impaired autophagy and mitophagy in Neuro-2a cell damage under hypoxic and/or high-glucose conditions.
Hypoxia Activates Src and Promotes Endocytosis Which Decreases MMP-2 Activity and Aggravates Renal Interstitial Fibrosis.
The RARS-MAD1L1 Fusion Gene Induces Cancer Stem Cell-like Properties and Therapeutic Resistance in Nasopharyngeal Carcinoma.
Effects of garlic polysaccharide on alcoholic liver fibrosis and intestinal microflora in mice.
Involvement of PINK1/Parkin-mediated mitophagy in paraquat- induced apoptosis in human lung epithelial-like A549 cells.
Oxymatrine attenuates brain hypoxic-ischemic injury from apoptosis and oxidative stress: role of p-Akt/GSK3β/HO-1/Nrf-2 signaling pathway.
RNF126 Quenches RNF168 Function in the DNA Damage Response.
1,3-Dichloro-2-Propanol inhibits autophagy via P53/AMPK/mTOR pathway in HepG2 cells.
Urea transport B gene induces melanoma B16 cell death via activation of p53 and mitochondrial apoptosis.
Type 3 innate lymphoid cell: a new player in liver fibrosis progression.
Long non-coding RNA BRE-AS1 represses non-small cell lung cancer cell growth and survival via up-regulating NR4A3.
Protein A from orange-spotted grouper nervous necrosis virus triggers type I interferon production in fish cell.
Overcoming resistance to mitochondrial apoptosis by BZML-induced mitotic catastrophe is enhanced by inhibition of autophagy in A549/Taxol cells.
Osteoglycin-induced VEGF Inhibition Enhances T Lymphocytes Infiltrating in Colorectal Cancer.
Restoration of 5-hydroxymethylcytosine by ascorbate blocks kidney tumour growth.
Matrine inhibits the proliferation and migration of lung cancer cells through regulation of the protein kinase B/glycogen synthase kinase-3β signaling pathways.
TNFSF14/LIGHT, a Non-Canonical NF-κB Stimulus, Induces the HIF Pathway.
NRAGE confers poor prognosis and promotes proliferation, invasion, and chemoresistance in gastric cancer.
Selenium-enriched yeast inhibited β-amyloid production and modulated autophagy in a triple transgenic mouse model of Alzheimer's disease.
Effects of Dahuang zhechong pill on doxorubicin-resistant SMMC-7721 xenografts in mice.
Uncoupling protein 1 expression in adipocytes derived from skeletal muscle fibro/adipogenic progenitors is under genetic and hormonal control.
Role of TGF-β activated kinase-1 inhibitor on the interaction between macrophages and mesangial cells on the condition of high glucose.
MiR-151a is involved in the pathogenesis of atopic dermatitis by regulating interleukin-12 receptor β2.
TIPE2 is negatively correlated with tissue factor and thrombospondin-1 expression in patients with bronchial asthma.
The enhancement of siPLK1 penetration across BBB and its anti glioblastoma activity in vivo by magnet and transferrin co-modified nanoparticle.
Identification of novel Nrf2 activators from Cinnamomum chartophyllum H.W. Li and their potential application of preventing oxidative insults in human lung epithelial cells.
Catalpol ameliorates hepatic insulin resistance in type 2 diabetes through acting on AMPK/NOX4/PI3K/AKT pathway.
Protective effect of methylallyl sulfone in the development of cigarette smoke extract-induced apoptosis in rats and HFL-1 cells.
Smurf1 restricts the antiviral function mediated by USP25 through promoting its ubiquitination and degradation.
GRASP55 Senses Glucose Deprivation through O-GlcNAcylation to Promote Autophagosome-Lysosome Fusion.
Role of silent information regulator 1 in the protective effect of hydrogen sulfide on homocysteine-induced cognitive dysfunction: Involving reduction of hippocampal ER stress.
Nogo-B receptor promotes epithelial-mesenchymal transition in non-small cell lung cancer cells through the Ras/ERK/Snail1 pathway.
GRHL2 suppresses tumor metastasis via regulation of transcriptional activity of RhoG in non-small cell lung cancer.
Silencing Rab14 represses the proliferation and migration of oral squamous cell carcinoma, and enhances cisplatin sensitivity.
3-Mercaptopyruvate Sulfurtransferase, Not Cystathionine β-Synthase Nor Cystathionine γ-Lyase, Mediates Hypoxia-Induced Migration of Vascular Endothelial Cells.
Antimycobacterial and Anti-inflammatory Mechanisms of Baicalin via Induced Autophagy in Macrophages Infected with Mycobacterium tuberculosis.
Variant Amino Acid Residues Alter the Enzyme Activity of Peanut Type 2 Diacylglycerol Acyltransferases.
Iridoids with Genipin Stem Nucleus Inhibit Lipopolysaccharide-Induced Inflammation and Oxidative Stress by Blocking the NF-κB Pathway in Polycystic Ovary Syndrome.
The USP7 Inhibitor P5091 Induces Cell Death in Ovarian Cancers with Different P53 Status.
α-Lipoic Acid Promotes Neurological Recovery After Ischemic Stroke by Activating the Nrf2/HO-1 Pathway to Attenuate Oxidative Damage.
Targeted kinase inhibition relieves slowness and tremor in a Drosophila model of LRRK2 Parkinson's disease.
Endoplasmic Reticulum Stress Is Involved in Cochlear Cell Apoptosis in a Cisplatin-Induced Ototoxicity Rat Model.
Role of Zebrafish fhl1A in Satellite Cell and Skeletal Muscle Development.
XRCC5 cooperates with p300 to promote cyclooxygenase-2 expression and tumor growth in colon cancers.
miR-125b-5p functions as a tumor suppressor gene partially by regulating HMGA2 in esophageal squamous cell carcinoma.
Autophagy promotes degradation of polyethyleneimine-alginate nanoparticles in endothelial progenitor cells.
Curcumin Activates AMPK Pathway and Regulates Lipid Metabolism in Rats Following Prolonged Clozapine Exposure.
Paeoniflorin attenuates incipient diabetic nephropathy in streptozotocin-induced mice by the suppression of the Toll-like receptor-2 signaling pathway.
Roux-en-Y Gastric Bypass Improves Hepatic Glucose Metabolism Involving Down-Regulation of Protein Tyrosine Phosphatase 1B in Obese Rats.
HOXD-AS1 functions as an oncogenic ceRNA to promote NSCLC cell progression by sequestering miR-147a.
Transcription Factor NFAT5 Promotes Glioblastoma Cell-driven Angiogenesis via SBF2-AS1/miR-338-3p-Mediated EGFL7 Expression Change.
Identification of Flavin-Containing Monooxygenase 5 (FMO5) as a Regulator of Glucose Homeostasis and a Potential Sensor of Gut Bacteria.
Visfatin induces the apoptosis of endothelial progenitor cells via the induction of pro-inflammatory mediators through the NF-κB pathway.
Mechanism of Lycium barbarum polysaccharides on primary cultured rat hippocampal neurons.
Downregulation of serum RAB27B confers improved prognosis and is associated with hepatocellular carcinoma progression through PI3K-AKT-P21 signaling.
Dendrobium nobile Lindl. alkaloids regulate metabolism gene expression in livers of mice.
APPL1 promotes the migration of gastric cancer cells by regulating Akt2 phosphorylation.
Thrombospondin-1 Production Regulates the Inflammatory Cytokine Secretion in THP-1 Cells Through NF-κB Signaling Pathway.
An Important Function of Petrosiol E in Inducing the Differentiation of Neuronal Progenitors and in Protecting Them against Oxidative Stress.
Anti-inflammatory capacity of Lactobacillus rhamnosus GG in monophasic variant Salmonella infected piglets is correlated with impeding NLRP6-mediated host inflammatory responses.
Ovarian cancer proliferation and apoptosis are regulated by human transfer RNA methyltransferase 9-likevia LIN9.
The role of long non-coding RNA PCA3 in epithelial ovarian carcinoma tumorigenesis and progression.
Inhibition of Starvation-Triggered Endoplasmic Reticulum Stress, Autophagy, and Apoptosis in ARPE-19 Cells by Taurine through Modulating the Expression of Calpain-1 and Calpain-2.
Evidence for a direct cross-talk between malic enzyme and the pentose phosphate pathway via structural interactions.
Ligand-dependent EphA7 signaling inhibits prostate tumor growth and progression.
Fluoride-Induced Autophagy via the Regulation of Phosphorylation of Mammalian Targets of Rapamycin in Mice Leydig Cells.
MicroRNA-23a promotes pancreatic cancer metastasis by targeting epithelial splicing regulator protein 1.
Epigenetic silencing of ASPP1 confers 5-FU resistance in clear cell renal cell carcinoma by preventing p53 activation.
Cryptotanshinone sensitizes antitumor effect of paclitaxel on tongue squamous cell carcinoma growth by inhibiting the JAK/STAT3 signaling pathway.
Spatiotemporal Expression of Bcl-2/Bax and Neural Cell Apoptosis in the Developing Lumbosacral Spinal Cord of Rat Fetuses with Anorectal Malformations.
Sialic acid-modified solid lipid nanoparticles as vascular endothelium-targeting carriers for ischemia-reperfusion-induced acute renal injury.
Lack of BACE1 S-palmitoylation reduces amyloid burden and mitigates memory deficits in transgenic mouse models of Alzheimer's disease.
Cell-autonomous adiposity through increased cell surface GLUT4 due to ankyrin-B deficiency.
Proteomics and metabolomics analysis of hepatic mitochondrial metabolism in alcohol-preferring and non-preferring rats.
Copper or/and arsenic induce oxidative stress-cascaded, nuclear factor kappa B-dependent inflammation and immune imbalance, trigging heat shock response in the kidney of chicken.
Hydrogen Sulfide Inhibits Chronic Unpredictable Mild Stress-Induced Depressive-Like Behavior by Upregulation of Sirt-1: Involvement in Suppression of Hippocampal Endoplasmic Reticulum Stress.
Inhibition of tissue transglutaminase attenuates lipopolysaccharide-induced inflammation in glial cells through AKT/mTOR signal pathway.
FGF7/FGFR2 signal promotes invasion and migration in human gastric cancer through upregulation of thrombospondin-1.
Embelin attenuates adipogenesis and lipogenesis through activating canonical Wnt signaling and inhibits high-fat diet-induced obesity.
Sulforaphane-cysteine induces apoptosis by sustained activation of ERK1/2 and caspase 3 in human glioblastoma U373MG and U87MG cells.
oxLDL antibody inhibits MCP-1 release in monocytes/macrophages by regulating Ca2+ /K+ channel flow.
TET3-mediated DNA oxidation promotes ATR-dependent DNA damage response.
Menin enhances c-Myc-mediated transcription to promote cancer progression.
Thyroid stimulating hormone increases hepatic gluconeogenesis via CRTC2.
Longikaurin A, a natural ent-kaurane, suppresses stemness in nasopharyngeal carcinoma cells.
Hypoxia promotes chemotherapy resistance by down-regulating SKA1 gene expression in human osteosarcoma.
miR-148a and miR-17-5p synergistically regulate milk TAG synthesis via PPARGC1A and PPARA in goat mammary epithelial cells.
MicroRNA-17-92 Regulates the Transcription Factor E2F3b during Myogenesis In Vitro and In Vivo.
Probiotics may delay the progression of nonalcoholic fatty liver disease by restoring the gut microbiota structure and improving intestinal endotoxemia.
Anti-tumor effect of evodiamine by inducing Akt-mediated apoptosis in hepatocellular carcinoma.
Upregulation of microRNA-574-3p in a human gastric cancer cell line AGS by TGF-β1.
Sulforaphane prevents bleomycin‑induced pulmonary fibrosis in mice by inhibiting oxidative stress via nuclear factor erythroid 2‑related factor‑2 activation.
Cerebrolysin alleviates cognitive deficits induced by chronic cerebral hypoperfusion by increasing the levels of plasticity-related proteins and decreasing the levels of apoptosis-related proteins in the rat hippocampus.
CADASIL mutant NOTCH3(R90C) decreases the viability of HS683 oligodendrocytes via apoptosis.
The MBNL3 splicing factor promotes hepatocellular carcinoma by increasing PXN expression through the alternative splicing of lncRNA-PXN-AS1.
Malvidin and cyanidin derivatives from açai fruit (Euterpe oleracea Mart.) counteract UV-A-induced oxidative stress in immortalized fibroblasts.
Selenium-Containing Polysaccharide-Protein Complex in Se-Enriched Ulva fasciata Induces Mitochondria-Mediated Apoptosis in A549 Human Lung Cancer Cells.
Deubiquitinase USP33 is negatively regulated by β-TrCP through ubiquitin-dependent proteolysis.
Transcription regulator TRIP-Br2 mediates ER stress-induced brown adipocytes dysfunction.
The role of the ATM/Chk/P53 pathway in mediating DNA damage in hand-foot syndrome induced by PLD.
Targeting P-glycoprotein function, p53 and energy metabolism: Combination of metformin and 2-deoxyglucose reverses the multidrug resistance of MCF-7/Dox cells to doxorubicin.
Knockdown of TREM-1 suppresses IL-1β-induced chondrocyte injury via inhibiting the NF-κB pathway.
Transdifferentiation of human male germline stem cells to hepatocytes in vivo via the transplantation under renal capsules.
Calycosin attenuates triglyceride accumulation and hepatic fibrosis in murine model of non-alcoholic steatohepatitis via activating farnesoid X receptor.
Single tumor-initiating cells evade immune clearance by recruiting type II macrophages.
Ontogeny, aging, and gender-related changes in hepatic multidrug resistant protein genes in rats.
Altered Expression of TXNIP in the peripheral leukocytes of patients with coronary atherosclerotic heart disease.
Effects of polysaccharide from Physalis alkekengi var. francheti on liver injury and intestinal microflora in type-2 diabetic mice.
Induction of autophagy by an oleanolic acid derivative, SZC017, promotes ROS-dependent apoptosis through Akt and JAK2/STAT3 signaling pathway in human lung cancer cells.
Glucose potentiates β-cell function by inducing Tph1 expression in rat islets.
POSH participates in epileptogenesis by increasing the surface expression of the NMDA receptor: a promising therapeutic target for epilepsy.
Regulation of AMH by oocyte-specific growth factors in human primary cumulus cells.
Effects of dimethyl carbonate-induced autophagic activation on follicular development in the mouse ovary.
MicroRNA-30e Functions as a Tumor Suppressor in Cervical Carcinoma Cells through Targeting GALNT7.
Piperlongumine suppresses bladder cancer invasion via inhibiting epithelial mesenchymal transition and F-actin reorganization.
Salvianolic acid B protects against lipopolysaccharide-induced behavioral deficits and neuroinflammatory response: involvement of autophagy and NLRP3 inflammasome.
Rho/ROCK Pathway Regulates Migration and Invasion of Esophageal Squamous Cell Carcinoma by Regulating Caveolin-1.
CAPE-pNO2 ameliorated diabetic nephropathy through regulating the Akt/NF-κB/ iNOS pathway in STZ-induced diabetic mice.
Synergistic inhibition of tumor growth by combination treatment with drugs against different subpopulations of glioblastoma cells.
Discovery of a Small-Molecule Bromodomain-Containing Protein 4 (BRD4) Inhibitor That Induces AMP-Activated Protein Kinase-Modulated Autophagy-Associated Cell Death in Breast Cancer.
Cadherin 6 is activated by Epstein-Barr virus LMP1 to mediate EMT and metastasis as an interplay node of multiple pathways in nasopharyngeal carcinoma.
Ultrasound reverses chemoresistance in breast cancer stem cell like cells by altering ABCG2 expression.
Indomethacin-based stimuli-responsive micelles combined with paclitaxel to overcome multidrug resistance.
De novo, deleterious sequence variants that alter the transcriptional activity of the homeoprotein PBX1 are associated with intellectual disability and pleiotropic developmental defects.
Ascl2 activation by YAP1/KLF5 ensures the self-renewability of colon cancer progenitor cells.
Adeno-associated virus 9-mediated Cdk5 inhibitory peptide reverses pathologic changes and behavioral deficits in the Alzheimer's disease mouse model.
Effect of GAPT extract on expression of tau protein and its phosphorylation related enzymes in hippocampal neurons of APPV717I transgenic mice.
Ubiquitin C-terminal hydrolase-L3 promotes interferon antiviral activity by stabilizing type I-interferon receptor.
Palbociclib induces activation of AMPK and inhibits hepatocellular carcinoma in a CDK4/6-independent manner.
NFATc3 mediates the sensitivity of gastric cancer cells to arsenic sulfide.
Apoptosis pattern and alterations of expression of apoptosis-related factors of supporting cells in Kölliker's organ in vivo in early stage after birth in rats.
Enteric dysbiosis-linked gut barrier disruption triggers early renal injury induced by chronic high salt feeding in mice.
Structure-based virtual screening and optimization of modulators targeting Hsp90-Cdc37 interaction.
Exogenous H2S facilitating ubiquitin aggregates clearance via autophagy attenuates type 2 diabetes-induced cardiomyopathy.
High expression of RBM8A predicts poor patient prognosis and promotes tumor progression in hepatocellular carcinoma.
Upregulated unique long 16 binding protein 1 detected in preeclamptic placenta affects human extravillous trophoblast cell line (HTR-8/SVneo) invasion by modulating the function of uterine natural killer cells.
Endogenous Stem Cells Were Recruited by Defocused Low-Energy Shock Wave in Treating Diabetic Bladder Dysfunction.
Autoinhibition of Dishevelled protein regulated by its extreme C terminus plays a distinct role in Wnt/β-catenin and Wnt/planar cell polarity (PCP) signaling pathways.
A novel glutaminase inhibitor-968 inhibits the migration and proliferation of non-small cell lung cancer cells by targeting EGFR/ERK signaling pathway.
Tenofovir and adefovir down-regulate mitochondrial chaperone TRAP1 and succinate dehydrogenase subunit B to metabolically reprogram glucose metabolism and induce nephrotoxicity.
Discovery of a small molecule targeting ULK1-modulated cell death of triple negative breast cancer in vitro and in vivo.
The role of TGF-β-activated kinase 1 in db/db mice and high glucose-induced macrophage.
B7-H4 expression in human infiltrating ductal carcinoma‑associated macrophages.
Interleukin-11 promotes epithelial-mesenchymal transition in anaplastic thyroid carcinoma cells through PI3K/Akt/GSK3β signaling pathway activation.
Functional characterization of hepatitis B virus core promoter mutants revealed transcriptional interference among co-terminal viral mRNAs.
Effect of Polygonatum odoratum extract on human breast cancer MDA-MB-231 cell proliferation and apoptosis.
Afamin promotes glucose metabolism in papillary thyroid carcinoma.
MicroRNA-181b suppresses TAG via target IRS2 and regulating multiple genes in the Hippo pathway.
HSPB1 deficiency sensitizes melanoma cells to hyperthermia induced cell death.
A comparison of incidences of bladder neck contracture of 80- versus 180-W GreenLight laser photoselective vaporization of benign prostatic hyperplasia.
Ubiquitin-dependent Turnover of Adenosine Deaminase Acting on RNA 1 (ADAR1) Is Required for Efficient Antiviral Activity of Type I Interferon.
Human epithelial-type ovarian tumour marker beta-2-microglobulin is regulated by the TGF-β signaling pathway.
AMPK activation protects cells from oxidative stress-induced senescence via autophagic flux restoration and intracellular NAD(+) elevation.
Pancreatic cancer risk variant in LINC00673 creates a miR-1231 binding site and interferes with PTPN11 degradation.
Deubiquitinase USP2a Sustains Interferons Antiviral Activity by Restricting Ubiquitination of Activated STAT1 in the Nucleus.
Homologous recombination-dependent repair of telomeric DSBs in proliferating human cells.
Blockade of TGF-β-activated kinase 1 prevents advanced glycation end products-induced inflammatory response in macrophages.
The PLC/PKC/Ras/MEK/Kv channel pathway is involved in uncarboxylated osteocalcin-regulated insulin secretion in rats.
Nuclear PTEN interferes with binding of Ku70 at double-strand breaks through post-translational poly(ADP-ribosyl)ation.
Berberine increases adipose triglyceride lipase in 3T3-L1 adipocytes through the AMPK pathway.
Senescence: novel insight into DLX3 mutations leading to enhanced bone formation in Tricho-Dento-Osseous syndrome.
H2O2 treatment or serum deprivation induces autophagy and apoptosis in naked mole-rat skin fibroblasts by inhibiting the PI3K/Akt signaling pathway.
Chronic stress and excessive glucocorticoid exposure both lead to altered Neuregulin-1/ErbB signaling in rat myocardium.
YB-1 regulates tiRNA-induced Stress Granule formation but not translational repression.
Enhanced SLC34A2 in breast cancer stem cell-like cells induces chemotherapeutic resistance to doxorubicin via SLC34A2-Bmi1-ABCC5 signaling.
Protective effect of melatonin on myenteric neuron damage in experimental colitis in rats.
Arsenic sulfide, the main component of realgar, a traditional Chinese medicine, induces apoptosis of gastric cancer cells in vitro and in vivo.
Cardiac microvascular barrier function mediates the protection of Tongxinluo against myocardial ischemia/reperfusion injury.
Elevated GAPDH expression is associated with the proliferation and invasion of lung and esophageal squamous cell carcinomas.
Gabarapl1 mediates androgen-regulated autophagy in prostate cancer.
MiR-101 sensitizes human nasopharyngeal carcinoma cells to radiation by targeting stathmin 1.
Formaldehyde exposure induces autophagy in testicular tissues of adult male rats.
Astrocyte elevated gene-1 promotes progression of cervical squamous cell carcinoma by inducing epithelial-mesenchymal transition via Wnt signaling.
MiR-200c inhibits autophagy and enhances radiosensitivity in breast cancer cells by targeting UBQLN1.
G-protein coupled receptor 34 activates Erk and phosphatidylinositol 3-kinase/Akt pathways and functions as alternative pathway to mediate p185Bcr-Abl-induced transformation and leukemogenesis.
8-p-Hdroxybenzoyl Tovarol Induces Paraptosis Like Cell Death and Protective Autophagy in Human Cervical Cancer HeLa Cells.
Annexin A3 as a potential target for immunotherapy of liver cancer stem-like cells.
Inhibition of JNK3 promotes apoptosis induced by BH3 mimetic S1 in chemoresistant human ovarian cancer cells.
Decreased expression of mucin-1 in endometriosis endometrium correlated with progesterone receptor B involved in infertility.
Tolerance to endoplasmic reticulum stress mediates cisplatin resistance in human ovarian cancer cells by maintaining endoplasmic reticulum and mitochondrial homeostasis.
IFIT5 positively regulates NF-κB signaling through synergizing the recruitment of IκB kinase (IKK) to TGF-β-activated kinase 1 (TAK1).
Mitophagy in APPsw/PS1dE9 transgenic mice and APPsw stably expressing in HEK293 cells.
G1/S Cell Cycle Checkpoint Dysfunction in Lymphoblasts from Sporadic Parkinson's Disease Patients.
Lentivirus vector-mediated gene transduction of CNGRC peptide in rat adipose stem cells.
Neuropilin-1 promotes epithelial-to-mesenchymal transition by stimulating nuclear factor-kappa B and is associated with poor prognosis in human oral squamous cell carcinoma.
Altered expression of hypoxia-inducible factor-1α (HIF-1α) and its regulatory genes in gastric cancer tissues.
Proteomics approaches for identification of tumor relevant protein targets in pulmonary squamous cell carcinoma by 2D-DIGE-MS.
The association of HMGB1 gene with the prognosis of HCC.
Tetramethylpyrazine ameliorates high glucose-induced endothelial dysfunction by increasing mitochondrial biogenesis.
Prognostic value of myeloid differentiation primary response 88 and Toll-like receptor 4 in breast cancer patients.
Elevated MiR-222-3p promotes proliferation and invasion of endometrial carcinoma via targeting ERα.
Matrix metalloproteinase 3 promotes cellular anti-dengue virus response via interaction with transcription factor NFκB in cell nucleus.
Cytotoxicity induced by nanobacteria and nanohydroxyapatites in human choriocarcinoma cells.
PNMA1 promotes cell growth in human pancreatic ductal adenocarcinoma.
mTOR inhibitor AZD8055 inhibits proliferation and induces apoptosis in laryngeal carcinoma.
Involvement of TLR4 in oxidized LDL/β2GPI/anti-β2GPI-induced transformation of macrophages to foam cells.
Ganoderma lucidum polysaccharides target a Fas/caspase dependent pathway to induce apoptosis in human colon cancer cells.
Atorvastatin induces autophagy of mesenchymal stem cells under hypoxia and serum deprivation conditions by activating the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway.
Geniposide and its iridoid analogs exhibit antinociception by acting at the spinal GLP-1 receptors.
Cryopreserved mouse fetal liver stromal cells treated with mitomycin C are able to support the growth of human embryonic stem cells.
USP33, a new player in lung cancer, mediates Slit-Robo signaling.
Neuroprotective role of BNIP3 under oxidative stress through autophagy in neuroblastoma cells.
Dysregulation of vitamin D metabolism in the brain and myocardium of rats following prolonged exposure to dexamethasone.
In vitro and in vivo protection against enterovirus 71 by an antisense phosphorothioate oligonucleotide.
Lipoxin A4 methyl ester ameliorates cognitive deficits induced by chronic cerebral hypoperfusion through activating ERK/Nrf2 signaling pathway in rats.
Direct interaction of 14-3-3ζ with ezrin promotes cell migration by regulating the formation of membrane ruffle.
Loss of Wdfy3 in mice alters cerebral cortical neurogenesis reflecting aspects of the autism pathology.
Bone marrow mesenchymal stem cells repair spinal cord ischemia/reperfusion injury by promoting axonal growth and anti-autophagy.
A central role for TRPS1 in the control of cell cycle and cancer development.
Cationic poly(amidoamine) dendrimers induced cyto-protective autophagy in hepatocellular carcinoma cells.
Ezrin is required for epithelial-mesenchymal transition induced by TGF-β1 in A549 cells.
Novel microRNA-like viral small regulatory RNAs arising during human hepatitis A virus infection.
Tetrachloro-p-benzoquinone induces hepatic oxidative damage and inflammatory response, but not apoptosis in mouse: the prevention of curcumin.
Chronic stress causes neuroendocrine-immune disturbances without affecting renal vitamin D metabolism in rats.
MicroRNA-145 inhibits cell proliferation by directly targeting ADAM17 in hepatocellular carcinoma.
Toxic effects of levofloxacin on rat annulus fibrosus cells: an in-vitro study.
Cholesterol-conjugated let-7a mimics: antitumor efficacy on hepatocellular carcinoma in vitro and in a preclinical orthotopic xenograft model of systemic therapy.
Phosphatidylinositol 3-kinase CB association with preoperative radiotherapy response in rectal adenocarcinoma.
Levels of human replication factor C4, a clamp loader, correlate with tumor progression and predict the prognosis for colorectal cancer.
Curcumin improves the integrity of blood-spinal cord barrier after compressive spinal cord injury in rats.
The sodium channel β1 subunit mediates outgrowth of neurite-like processes on breast cancer cells and promotes tumour growth and metastasis.
17β-Estradiol protects against apoptosis induced by levofloxacin in rat nucleus pulposus cells by upregulating integrin α2β1.
Nitro-oleic acid downregulates lipoprotein-associated phospholipase A2 expression via the p42/p44 MAPK and NFκB pathways.
Microcystin-LR stabilizes c-myc protein by inhibiting protein phosphatase 2A in HEK293 cells.
Chemical characterization and antitumor activities of polysaccharide extracted from Ganoderma lucidum.
A caspase-dependent pathway is involved in Wnt/β-catenin signaling promoted apoptosis in Bacillus Calmette-Guerin infected RAW264.7 macrophages.
HMG-CoA reductase is negatively associated with PCV2 infection and PCV2-induced apoptotic cell death.
Downregulation of p16(ink4a) inhibits cell proliferation and induces G1 cell cycle arrest in cervical cancer cells.
Zebrafish Cacna1fa is required for cone photoreceptor function and synaptic ribbon formation.
TNF-α promotes early atherosclerosis by increasing transcytosis of LDL across endothelial cells: crosstalk between NF-κB and PPAR-γ.
Effects of natural mineral-rich water consumption on the expression of sirtuin 1 and angiogenic factors in the erectile tissue of rats with fructose-induced metabolic syndrome.
Ruthenium(II) polypyridyl complexes: cellular uptake, cell image and apoptosis of HeLa cancer cells induced by double targets.
Lactobacillus casei reduces susceptibility to type 2 diabetes via microbiota-mediated body chloride ion influx.
Nanoscale chromatin profiling of gastric adenocarcinoma reveals cancer-associated cryptic promoters and somatically acquired regulatory elements.
Chondroprotective effects and multi-target mechanisms of Icariin in IL-1 beta-induced human SW 1353 chondrosarcoma cells and a rat osteoarthritis model.
Protection of ischemic post conditioning against transient focal ischemia-induced brain damage is associated with inhibition of neuroinflammation via modulation of TLR2 and TLR4 pathways.
Expression of SPRR3 is associated with tumor cell proliferation and invasion in glioblastoma multiforme.
MiR-451 increases radiosensitivity of nasopharyngeal carcinoma cells by targeting ras-related protein 14 (RAB14).
Fluoride affects calcium homeostasis and osteogenic transcription factor expressions through L-type calcium channels in osteoblast cell line.
MicroRNA-15b promotes neurogenesis and inhibits neural progenitor proliferation by directly repressing TET3 during early neocortical development.
Lentiviral vector-mediated RBM5 overexpression downregulates EGFR expression in human non-small cell lung cancer cells.
Blocking autophagy enhanced cytotoxicity induced by recombinant human arginase in triple-negative breast cancer cells.
The expression level of TRAF1 in human gastric mucosa is related to virulence genotypes of Helicobacter pylori.
Reversal of multidrug resistance in vitro and in vivo by 5-N-formylardeemin, a new ardeemin derivative.
oxLDL/β2GPI/anti-β2GPI complex induced macrophage differentiation to foam cell involving TLR4/NF-kappa B signal transduction pathway.
Anthocyanin-rich fractions from red raspberries attenuate inflammation in both RAW264.7 macrophages and a mouse model of colitis.
The crucial role of Atg5 in cortical neurogenesis during early brain development.
si-DNMT1 restore tumor suppressor genes expression through the reversal of DNA hypermethylation in cholangiocarcinoma.
NLRP3 deficiency ameliorates neurovascular damage in experimental ischemic stroke.
A synergic role of caspase-6 and caspase-3 in Tau truncation at D421 induced by H2O 2.
miR-200c inhibits metastasis of breast cancer cells by targeting HMGB1.
Epigallocatechin-3-gallate inhibits TF and TNF-α expression induced by the anti-β2GPI/β2GPI complex in human THP-1 cells.
Association analysis of UGT1A genotype and haplotype with SN-38 glucuronidation in human livers.
Activation of spinal glucagon-like peptide-1 receptors specifically suppresses pain hypersensitivity.
Ezh2 regulates adult hippocampal neurogenesis and memory.
Ubiquitin B in cervical cancer: critical for the maintenance of cancer stem-like cell characters.
Simvastatin alleviates hyperpermeability of glomerular endothelial cells in early-stage diabetic nephropathy by inhibition of RhoA/ROCK1.
NOD2 deficiency protects against cardiac remodeling after myocardial infarction in mice.
Scutellarin attenuates hypertension-induced expression of brain Toll-like receptor 4/nuclear factor kappa B.
Anti-β2GPI/β2GPI stimulates activation of THP-1 cells through TLR4/MD-2/MyD88 and NF-κB signaling pathways.
Overexpression of 4EBP1, p70S6K, Akt1 or Akt2 differentially promotes Coxsackievirus B3-induced apoptosis in HeLa cells.
L-3-n-butylphthalide protects against vascular dementia via activation of the Akt kinase pathway.
Specific deletion of Cdc42 does not affect meiotic spindle organization/migration and homologous chromosome segregation but disrupts polarity establishment and cytokinesis in mouse oocytes.
Nucleoside analog inhibits microRNA-214 through targeting heat-shock factor 1 in human epithelial ovarian cancer.
Astragaloside IV attenuates inflammatory cytokines by inhibiting TLR4/NF-кB signaling pathway in isoproterenol-induced myocardial hypertrophy.
Identification and analysis of glycogen synthase kinase 3 beta1 interactome.
Concurrent blockade of NF-κB and Akt pathways potentiates cisplatin's antitumor activity in vivo.
Anti-inflammatory mechanism of taurine against ischemic stroke is related to down-regulation of PARP and NF-κB.
Surgery upregulates high mobility group box-1 and disrupts the blood-brain barrier causing cognitive dysfunction in aged rats.
Regulation of fibroblast growth factor-2 expression and cell cycle progression by an endogenous antisense RNA.
Rosuvastatin treatment activates JAK-STAT pathway and increases efficacy of allogeneic mesenchymal stem cell transplantation in infarcted hearts.
Involvement of IRAKs and TRAFs in anti-β₂GPI/β₂GPI-induced tissue factor expression in THP-1 cells.
Atorvastatin prevents mesenchymal stem cells from hypoxia and serum-free injury through activating AMP-activated protein kinase.
Lentiviral-mediated siRNA targeted against osteopontin suppresses the growth and metastasis of gastric cancer cells.
Perturbation of survivin expression affects chromosome alignment and spindle checkpoint in mouse oocyte meiotic maturation.
[Effects of paclitaxel and gefitinib on the proliferation and cell cycle of human lung adenocarcinoma cell SPC-A1.].
Yu SS, Li ZY, Xu XZ, Yao F, Luo Y, Liu YC, Cheng L, Zheng MG, Jing JH
Neural regeneration research 2022 May;17(5):1072-1079
Neural regeneration research 2022 May;17(5):1072-1079
Injectable self-healing hydrogel with siRNA delivery property for sustained STING silencing and enhanced therapy of intervertebral disc degeneration.
Chen J, Zhu H, Zhu Y, Zhao C, Wang S, Zheng Y, Xie Z, Jin Y, Song H, Yang L, Zhang J, Dai J, Hu Z, Wang H
Bioactive materials 2022 Mar;9:29-43
Bioactive materials 2022 Mar;9:29-43
Systematic characterization of the metabolites of defatted walnut powder extract in vivo and screening of the mechanisms against NAFLD by UPLC-Q-Exactive Orbitrap MS combined with network pharmacology.
Ren SM, Zhang QZ, Jiang M, Chen ML, Xu XJ, Wang DM, Pan YN, Liu XQ
Journal of ethnopharmacology 2022 Mar 1;285:114870
Journal of ethnopharmacology 2022 Mar 1;285:114870
Moringa oleifera Lam. seed extract protects kidney function in rats with diabetic nephropathy by increasing GSK-3β activity and activating the Nrf2/HO-1 pathway.
Wen Y, Liu Y, Huang Q, Liu R, Liu J, Zhang F, Liu S, Jiang Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jan;95:153856
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jan;95:153856
Ror2 mediates chronic post-thoracotomy pain by inducing the transformation of A1/A2 reactive astrocytes in rats.
Liu C, Shen L, Xu L, Zhu A, Huang Y
Cellular signalling 2022 Jan;89:110183
Cellular signalling 2022 Jan;89:110183
Resveratrol Improves Synaptic Plasticity in Hypoxic-Ischemic Brain Injury in Neonatal Mice via Alleviating SIRT1/NF-κB Signaling-Mediated Neuroinflammation.
Peng X, Wang J, Peng J, Jiang H, Le K
Journal of molecular neuroscience : MN 2022 Jan;72(1):113-125
Journal of molecular neuroscience : MN 2022 Jan;72(1):113-125
Inflammatory cell-derived CXCL3 promotes pancreatic cancer metastasis through a novel myofibroblast-hijacked cancer escape mechanism.
Sun X, He X, Zhang Y, Hosaka K, Andersson P, Wu J, Wu J, Jing X, Du Q, Hui X, Ding B, Guo Z, Hong A, Liu X, Wang Y, Ji Q, Beyaert R, Yang Y, Li Q, Cao Y
Gut 2022 Jan;71(1):129-147
Gut 2022 Jan;71(1):129-147
A calcium phosphate drug carrier loading with 5-fluorouracil achieving a synergistic effect for pancreatic cancer therapy.
Chen J, Qiu M, Zhang S, Li B, Li D, Huang X, Qian Z, Zhao J, Wang Z, Tang D
Journal of colloid and interface science 2022 Jan;605:263-273
Journal of colloid and interface science 2022 Jan;605:263-273
SIRT1 induces the accumulation of TAMs at colorectal cancer tumor sites via the CXCR4/CXCL12 axis.
Fang H, Huang Y, Luo Y, Tang J, Yu M, Zhang Y, Zhong M
Cellular immunology 2022 Jan;371:104458
Cellular immunology 2022 Jan;371:104458
Inhibition of progesterone receptor membrane component-1 exacerbates neonatal hypoxic-ischemic cerebral damage in male mice.
Sun X, Hu Y, Zhou H, Wang S, Zhou C, Lin L, Zhu T, Ge J, Han J, Zhou Y, Jin G, Wang Y, Zu J, Shi H, Yang X, Zan K, Wang J, Hua F
Experimental neurology 2022 Jan;347:113893
Experimental neurology 2022 Jan;347:113893
Electroacupuncture alleviates spatial memory deficits in METH withdrawal mice by enhancing astrocyte-mediated glutamate clearance in the dCA1.
He T, Li N, Shi P, Xu X, Nie J, Lu X, Yu P, Fan Y, Ge F, Guan X
Addiction biology 2022 Jan;27(1):e13068
Addiction biology 2022 Jan;27(1):e13068
Zinc-finger protein 750 mitigates malignant biological behavior of oral CSC-like cells enriched from parental CAL-27 cells.
Xu C, Yang HL, Yang YK, Pan L, Chen HY
Oncology letters 2022 Jan;23(1):28
Oncology letters 2022 Jan;23(1):28
DNMT3B regulates proliferation of A549 cells through the microRNA-152-3p/NCAM1 pathway.
Yang B, Huang S, Chen H, Li R, Hou S, Zhao J, Li Y
Oncology letters 2022 Jan;23(1):11
Oncology letters 2022 Jan;23(1):11
Morphological changes of macrophages and their potential contribution to tendon healing.
Yang QQ, Zhang L, Zhou YL, Tang JB
Colloids and surfaces. B, Biointerfaces 2022 Jan;209(Pt 1):112145
Colloids and surfaces. B, Biointerfaces 2022 Jan;209(Pt 1):112145
METTL3 Regulates Liver Homeostasis, Hepatocyte Ploidy, and Circadian Rhythm-Controlled Gene Expression in Mice.
Barajas JM, Lin CH, Sun HL, Alencastro F, Zhu AC, Aljuhani M, Navari L, Yilmaz SA, Yu L, Corps K, He C, Duncan AW, Ghoshal K
The American journal of pathology 2022 Jan;192(1):56-71
The American journal of pathology 2022 Jan;192(1):56-71
Pyridoxamine ameliorates methylglyoxal-induced macrophage dysfunction to facilitate tissue repair in diabetic wounds.
Jiang M, Yakupu A, Guan H, Dong J, Liu Y, Song F, Tang J, Tian M, Niu Y, Lu S
International wound journal 2022 Jan;19(1):52-63
International wound journal 2022 Jan;19(1):52-63
RNF2 promotes the progression of colon cancer by regulating ubiquitination and degradation of IRF4.
Wang J, Ouyang X, Zhou Z, Mao S, Niu X, Li H, Xu W, Song Y, Cao J, Lai B
Biochimica et biophysica acta. Molecular cell research 2022 Jan;1869(1):119162
Biochimica et biophysica acta. Molecular cell research 2022 Jan;1869(1):119162
Silencing TXNIP ameliorates high uric acid-induced insulin resistance via the IRS2/AKT and Nrf2/HO-1 pathways in macrophages.
Yu W, Chen C, Zhuang W, Wang W, Liu W, Zhao H, Lv J, Xie, Wang Q, He F, Xu C, Chen B, Yamamoto T, Koyama H, Cheng J
Free radical biology & medicine 2022 Jan;178:42-53
Free radical biology & medicine 2022 Jan;178:42-53
Mettl3 inhibits the apoptosis and autophagy of chondrocytes in inflammation through mediating Bcl2 stability via Ythdf1-mediated m6A modification.
He Y, Wang W, Xu X, Yang B, Yu X, Wu Y, Wang J
Bone 2022 Jan;154:116182
Bone 2022 Jan;154:116182
Overexpression of DOCK6 in oral squamous cell cancer promotes cellular migration and invasion and is associated with poor prognosis.
Zhang ZY, Sun YY, Wang HC, Fu WN, Sun CF
Archives of oral biology 2022 Jan;133:105297
Archives of oral biology 2022 Jan;133:105297
Cotargeting of Bcl-2 and Mcl-1 shows promising antileukemic activity against AML cells including those with acquired cytarabine resistance.
Liu F, Zhao Q, Su Y, Lv J, Gai Y, Liu S, Lin H, Wang Y, Wang G
Experimental hematology 2022 Jan;105:39-49
Experimental hematology 2022 Jan;105:39-49
ERK/p38/ROS burst responses to environmentally relevant concentrations of diphenyl phosphate-evoked neutrophil extracellular traps formation: Assessing the role of autophagy.
Li S, Ma Y, Ye S, Hu D, Xiao F
Journal of hazardous materials 2022 Jan 5;421:126758
Journal of hazardous materials 2022 Jan 5;421:126758
Novel 5-fluorouracil sensitizers for colorectal cancer therapy: Design and synthesis of S1P receptor 2 (S1PR2) antagonists.
Luo D, Guo Z, Zhao X, Wu L, Liu X, Zhang Y, Zhang Y, Deng Z, Qu X, Cui S, Wan S
European journal of medicinal chemistry 2022 Jan 5;227:113923
European journal of medicinal chemistry 2022 Jan 5;227:113923
Saponins from Nigella glandulifera seeds attenuate collagen-induced rheumatoid arthritis in rats via the OPG/RANKL/NF-κB and Ang/Tie-2 pathways.
Jiang H, Xu F, Zeng L, Li C, Chen Y, Wang L, Li Z, Liu R
Journal of ethnopharmacology 2022 Jan 30;283:114714
Journal of ethnopharmacology 2022 Jan 30;283:114714
Guizhi-Shaoyao-Zhimu decoction attenuates monosodium urate crystal-induced inflammation through inactivation of NF-κB and NLRP3 inflammasome.
Zhou GQ, Chen G, Yang J, Qin WY, Ping J
Journal of ethnopharmacology 2022 Jan 30;283:114707
Journal of ethnopharmacology 2022 Jan 30;283:114707
The ethanol extract of flower buds of Tussilago farfara L. attenuates cigarette smoke-induced lung inflammation through regulating NLRP3 inflammasome, Nrf2, and NF-κB.
Xu LT, Wang T, Fang KL, Zhao Y, Wang XN, Ren DM, Shen T
Journal of ethnopharmacology 2022 Jan 30;283:114694
Journal of ethnopharmacology 2022 Jan 30;283:114694
Sodium hydrosulfide reverses β2-microglobulin-induced depressive-like behaviors of male Sprague-Dawley rats: Involving improvement of synaptic plasticity and enhancement of Warburg effect in hippocampus.
Yang SQ, Tang YY, Zeng D, Tian Q, Wei HJ, Wang CY, Zhang P, Chen YJ, Zou W, Tang XQ
Behavioural brain research 2022 Jan 24;417:113562
Behavioural brain research 2022 Jan 24;417:113562
Salubrinal protects against inflammatory response in macrophage and attenuates psoriasiform skin inflammation by antagonizing NF-κB signaling pathway.
Shangguan Y, Chen Y, Ma Y, Zhao Y, He Y, Li W
Biochemical and biophysical research communications 2022 Jan 22;589:63-70
Biochemical and biophysical research communications 2022 Jan 22;589:63-70
Pyk2 suppresses contextual fear memory in an autophosphorylation-independent manner.
Zheng J, Suo L, Zhou Y, Jia L, Li J, Kuang Y, Cui D, Zhang X, Wu Q
Journal of molecular cell biology 2022 Jan 21;13(11):808-821
Journal of molecular cell biology 2022 Jan 21;13(11):808-821
The amino acids of Autographa californica multiple nucleopolyhedrovirus P48 critical for the association with Ac93 are important for the nuclear egress of nucleocapsids and efficient formation of intranuclear microvesicles.
Wang Y, He J, Mo M, Cai Q, Wu W, Yuan M, Yang K
Virus research 2022 Jan 15;308:198644
Virus research 2022 Jan 15;308:198644
Ellagic acid ameliorates paraquat-induced liver injury associated with improved gut microbial profile.
Qi M, Wang N, Xiao Y, Deng Y, Zha A, Tan B, Wang J, Yin Y, Liao P
Environmental pollution (Barking, Essex : 1987) 2022 Jan 15;293:118572
Environmental pollution (Barking, Essex : 1987) 2022 Jan 15;293:118572
The PERK/PKR-eIF2α Pathway Negatively Regulates Porcine Hemagglutinating Encephalomyelitis Virus Replication by Attenuating Global Protein Translation and Facilitating Stress Granule Formation.
Shi J, Li Z, Xu R, Zhang J, Zhou Q, Gao R, Lu H, Lan Y, Zhao K, He H, Gao F, He W
Journal of virology 2022 Jan 12;96(1):e0169521
Journal of virology 2022 Jan 12;96(1):e0169521
Anti-tumor effect of Yanggan Huayu granule by inducing AKT-mediated apoptosis in hepatocellular carcinoma.
Shen Y, Yang F, Peng H, Zhang G, Zhu F, Xu H, Shi L
Journal of ethnopharmacology 2022 Jan 10;282:114601
Journal of ethnopharmacology 2022 Jan 10;282:114601
Tanshinone IIA alleviates NLRP3 inflammasome-mediated pyroptosis in Mycobacterium tuberculosis-(H37Ra-) infected macrophages by inhibiting endoplasmic reticulum stress.
Li Y, Fu Y, Sun J, Shen J, Liu F, Ning B, Lu Z, Wei L, Jiang X
Journal of ethnopharmacology 2022 Jan 10;282:114595
Journal of ethnopharmacology 2022 Jan 10;282:114595
Overexpression of Lin28a induces a primary ovarian insufficiency phenotype via facilitation of primordial follicle activation in mice.
Chen J, Liu W, Lee KF, Liu K, Wong BPC, Shu-Biu Yeung W
Molecular and cellular endocrinology 2022 Jan 1;539:111460
Molecular and cellular endocrinology 2022 Jan 1;539:111460
PTP70-2, a novel polysaccharide from Polygala tenuifolia, prevents neuroinflammation and protects neurons by suppressing the TLR4-mediated MyD88/NF-κB signaling pathway.
Chen H, Zhong J, Li J, Zeng Z, Yu Q, Yan C
International journal of biological macromolecules 2022 Jan 1;194:546-555
International journal of biological macromolecules 2022 Jan 1;194:546-555
Neuroglobin expression and function in the temporal cortex of bilirubin encephalopathy rats.
Hu JH, Fan P, Zhang LR, Chen CY, Xu J, Huang J, Lu WT, Zhu SJ, Qiu GP, Xu SY, Ran JH, Gan SW
Anatomical record (Hoboken, N.J. : 2007) 2022 Feb;305(2):254-264
Anatomical record (Hoboken, N.J. : 2007) 2022 Feb;305(2):254-264
Role of TGF-β1 in Fluoride-Treated Osteoblasts at Different Stages.
Jiang N, Xu W, Zhang Z, Jin H, Yang Y, Zhang J, Xu H
Biological trace element research 2022 Feb;200(2):740-748
Biological trace element research 2022 Feb;200(2):740-748
Zinc Protects against Heat Stress-Induced Apoptosis via the Inhibition of Endoplasmic Reticulum Stress in TM3 Leydig Cells.
Xiong Y, Li J, He S
Biological trace element research 2022 Feb;200(2):728-739
Biological trace element research 2022 Feb;200(2):728-739
miRNA-338-3p inhibits glioma cell proliferation and progression by targeting MYT1L.
Yu Z, Liu Y, Li Y, Zhang J, Peng J, Gong J, Xia Y, Wang L
Brain research bulletin 2022 Feb;179:1-12
Brain research bulletin 2022 Feb;179:1-12
Vibrio harveyi infections induce production of proinflammatory cytokines in murine peritoneal macrophages via activation of p38 MAPK and NF-κB pathways, but reversed by PI3K/AKT pathways.
Yu G, Yu H, Yang Q, Wang J, Fan H, Liu G, Wang L, Bello BK, Zhao P, Zhang H, Dong J
Developmental and comparative immunology 2022 Feb;127:104292
Developmental and comparative immunology 2022 Feb;127:104292
Anti-proliferation and anti-inflammation effects of corilagin in rheumatoid arthritis by downregulating NF-κB and MAPK signaling pathways.
Shen Y, Teng L, Qu Y, Liu J, Zhu X, Chen S, Yang L, Huang Y, Song Q, Fu Q
Journal of ethnopharmacology 2022 Feb 10;284:114791
Journal of ethnopharmacology 2022 Feb 10;284:114791
Physiological and transcriptomic analyses reveal the toxicological mechanism and risk assessment of environmentally-relevant waterborne tetracycline exposure on the gills of tilapia (Oreochromis niloticus).
Xu YC, Liu GH, Xu YH, Zhao T, Zheng H, Tan XY
The Science of the total environment 2022 Feb 1;806(Pt 3):151290
The Science of the total environment 2022 Feb 1;806(Pt 3):151290
Aspirin relieves the calcification of aortic smooth muscle cells by enhancing the heat shock response.
Shen Q, Chen Q, Liu Y, Xue X, Shen X, He Q, Wang G, Han F
Pharmaceutical biology 2022 Dec;60(1):17-24
Pharmaceutical biology 2022 Dec;60(1):17-24
Inhibiting Hyper-O-GlcNAcylation of c-Myc accelerate diabetic wound healing by alleviating keratinocyte dysfunction.
Zhang J, Yang P, Liu D, Gao M, Wang J, Yu T, Zhang X, Liu Y
Burns & trauma 2021;9:tkab031
Burns & trauma 2021;9:tkab031
Comprehensive analysis of abnormal expression, prognostic value and oncogenic role of the hub gene FN1 in pancreatic ductal adenocarcinoma via bioinformatic analysis and in vitro experiments.
Lei X, Chen G, Li J, Wen W, Gong J, Fu J
PeerJ 2021;9:e12141
PeerJ 2021;9:e12141
Identification of KIF4A as a pan-cancer diagnostic and prognostic biomarker via bioinformatics analysis and validation in osteosarcoma cell lines.
Pan J, Lei X, Mao X
PeerJ 2021;9:e11455
PeerJ 2021;9:e11455
PPy@Fe3O4 Nanoparticles Inhibit Tumor Growth and Metastasis Through Chemodynamic and Photothermal Therapy in Non-small Cell Lung Cancer.
Fang D, Jin H, Huang X, Shi Y, Liu Z, Ben S
Frontiers in chemistry 2021;9:789934
Frontiers in chemistry 2021;9:789934
Cadherin-12 Regulates Neurite Outgrowth Through the PKA/Rac1/Cdc42 Pathway in Cortical Neurons.
Guo B, Qi M, Huang S, Zhuo R, Zhang W, Zhang Y, Xu M, Liu M, Guan T, Liu Y
Frontiers in cell and developmental biology 2021;9:768970
Frontiers in cell and developmental biology 2021;9:768970
LncRNA FEZF1-AS1 Promotes Multi-Drug Resistance of Gastric Cancer Cells via Upregulating ATG5.
Gui Z, Zhao Z, Sun Q, Shao G, Huang J, Zhao W, Kuang Y
Frontiers in cell and developmental biology 2021;9:749129
Frontiers in cell and developmental biology 2021;9:749129
Eicosapentaenoic Acid-Induced Autophagy Attenuates Intervertebral Disc Degeneration by Suppressing Endoplasmic Reticulum Stress, Extracellular Matrix Degradation, and Apoptosis.
Lin Z, Ni L, Teng C, Zhang Z, Wu L, Jin Y, Lu X, Lin Z
Frontiers in cell and developmental biology 2021;9:745621
Frontiers in cell and developmental biology 2021;9:745621
Autophagy Regulates VDAC3 Ubiquitination by FBXW7 to Promote Erastin-Induced Ferroptosis in Acute Lymphoblastic Leukemia.
Zhu T, Liu B, Wu D, Xu G, Fan Y
Frontiers in cell and developmental biology 2021;9:740884
Frontiers in cell and developmental biology 2021;9:740884
TMT-Based Proteomic Explores the Influence of DHEA on the Osteogenic Differentiation of hBMSCs.
Liang X, He M, Zhu B, Zhu Y, He X, Liu D, Wei Q
Frontiers in cell and developmental biology 2021;9:726549
Frontiers in cell and developmental biology 2021;9:726549
ESRRB Facilitates the Conversion of Trophoblast-Like Stem Cells From Induced Pluripotent Stem Cells by Directly Regulating CDX2.
Yu S, Zhang R, Shen Q, Zhu Z, Zhang J, Wu X, Zhao W, Li N, Yang F, Wei H, Hua J
Frontiers in cell and developmental biology 2021;9:712224
Frontiers in cell and developmental biology 2021;9:712224
Cyclophosphamide Exposure Causes Long-Term Detrimental Effect of Oocytes Developmental Competence Through Affecting the Epigenetic Modification and Maternal Factors' Transcription During Oocyte Growth.
Yang W, Ma Y, Jin J, Ren P, Zhou H, Xu S, Zhang Y, Hu Z, Rong Y, Dai Y, Zhang Y, Zhang S
Frontiers in cell and developmental biology 2021;9:682060
Frontiers in cell and developmental biology 2021;9:682060
The E3 Ligase PIAS1 Regulates p53 Sumoylation to Control Stress-Induced Apoptosis of Lens Epithelial Cells Through the Proapoptotic Regulator Bax.
Nie Q, Chen H, Zou M, Wang L, Hou M, Xiang JW, Luo Z, Gong XD, Fu JL, Wang Y, Zheng SY, Xiao Y, Gan YW, Gao Q, Bai YY, Wang JM, Zhang L, Tang XC, Hu X, Gong L, Liu Y, Li DW
Frontiers in cell and developmental biology 2021;9:660494
Frontiers in cell and developmental biology 2021;9:660494
SARS-CoV-2 Host Receptor ACE2 Protein Expression Atlas in Human Gastrointestinal Tract.
An X, Lin W, Liu H, Zhong W, Zhang X, Zhu Y, Wang X, Li J, Sheng Q
Frontiers in cell and developmental biology 2021;9:659809
Frontiers in cell and developmental biology 2021;9:659809
MYC Enhances Cholesterol Biosynthesis and Supports Cell Proliferation Through SQLE.
Yang F, Kou J, Liu Z, Li W, Du W
Frontiers in cell and developmental biology 2021;9:655889
Frontiers in cell and developmental biology 2021;9:655889
NTNG1 Modulates Cisplatin Resistance in Epithelial Ovarian Cancer Cells via the GAS6/AXL/Akt Pathway.
Fang S, Luo Y, Zhang Y, Wang H, Liu Q, Li X, Yu T
Frontiers in cell and developmental biology 2021;9:652325
Frontiers in cell and developmental biology 2021;9:652325
TAp63α Is Involved in Tobacco Smoke-Induced Lung Cancer EMT and the Anti-cancer Activity of Curcumin via miR-19 Transcriptional Suppression.
Xie C, Zhu J, Yang X, Huang C, Zhou L, Meng Z, Li X, Zhong C
Frontiers in cell and developmental biology 2021;9:645402
Frontiers in cell and developmental biology 2021;9:645402
Grb2 Induces Cardiorenal Syndrome Type 3: Roles of IL-6, Cardiomyocyte Bioenergetics, and Akt/mTOR Pathway.
Wang J, Sun X, Wang X, Cui S, Liu R, Liu J, Fu B, Gong M, Wang C, Shi Y, Chen Q, Cai G, Chen X
Frontiers in cell and developmental biology 2021;9:630412
Frontiers in cell and developmental biology 2021;9:630412
Zirconia Nanoparticles Induce HeLa Cell Death Through Mitochondrial Apoptosis and Autophagy Pathways Mediated by ROS.
Shang Y, Wang Q, Li J, Liu H, Zhao Q, Huang X, Dong H, Chen W, Gui R, Nie X
Frontiers in chemistry 2021;9:522708
Frontiers in chemistry 2021;9:522708
Maslinic Acid Attenuates Ischemia/Reperfusion Injury-Induced Myocardial Inflammation and Apoptosis by Regulating HMGB1-TLR4 Axis.
Li Q, Xu M, Li Z, Li T, Wang Y, Chen Q, Wang Y, Feng J, Yin X, Lu C
Frontiers in cardiovascular medicine 2021;8:768947
Frontiers in cardiovascular medicine 2021;8:768947
Loss of Hepatic Surf4 Depletes Lipid Droplets in the Adrenal Cortex but Does Not Impair Adrenal Hormone Production.
Chang X, Zhao Y, Qin S, Wang H, Wang B, Zhai L, Liu B, Gu HM, Zhang DW
Frontiers in cardiovascular medicine 2021;8:764024
Frontiers in cardiovascular medicine 2021;8:764024
S-Propargyl-Cysteine Attenuates Diabetic Cardiomyopathy in db/db Mice Through Activation of Cardiac Insulin Receptor Signaling.
Li Y, Xie KF, Chang YH, Wang C, Chen Y, Wang MJ, Zhu YC
Frontiers in cardiovascular medicine 2021;8:737191
Frontiers in cardiovascular medicine 2021;8:737191
The Regulation of Staphylococcus aureus-Induced Inflammatory Responses in Bovine Mammary Epithelial Cells.
Cai M, Fan W, Li X, Sun H, Dai L, Lei D, Dai Y, Liao Y
Frontiers in veterinary science 2021;8:683886
Frontiers in veterinary science 2021;8:683886
β-Sitosterol Ameliorates Endometrium Receptivity in PCOS-Like Mice: The Mediation of Gut Microbiota.
Yu Y, Cao Y, Huang W, Liu Y, Lu Y, Zhao J
Frontiers in nutrition 2021;8:667130
Frontiers in nutrition 2021;8:667130
Exosomal MicroRNA-181a Derived From Mesenchymal Stem Cells Improves Gut Microbiota Composition, Barrier Function, and Inflammatory Status in an Experimental Colitis Model.
Gu L, Ren F, Fang X, Yuan L, Liu G, Wang S
Frontiers in medicine 2021;8:660614
Frontiers in medicine 2021;8:660614
Liraglutide Protects Nucleus Pulposus Cells Against High-Glucose Induced Apoptosis by Activating PI3K/Akt/ mTOR/Caspase-3 and PI3K/Akt/GSK3β/Caspase-3 Signaling Pathways.
Yao M, Zhang J, Li Z, Bai X, Ma J, Li Y
Frontiers in medicine 2021;8:630962
Frontiers in medicine 2021;8:630962
Hydroxysafflor yellow A acutely attenuates blood-brain barrier permeability, oxidative stress, inflammation and apoptosis in traumatic brain injury in rats1.
Xu J, Zhan T, Zheng W, Huang YK, Chen K, Zhang XH, Ren P, Huang X
Acta cirurgica brasileira 2021;35(12):e351202
Acta cirurgica brasileira 2021;35(12):e351202
Autophagy Prevents Osteocyte Cell Death under Hypoxic Conditions.
Kurihara M, Mukudai Y, Watanabe H, Asakura M, Abe Y, Houri A, Chikuda J, Shimane T, Shirota T
Cells, tissues, organs 2021;210(5-6):326-338
Cells, tissues, organs 2021;210(5-6):326-338
Long Noncoding RNA HCG9 Promotes Osteosarcoma Progression through RAD51 by Acting as a ceRNA of miR-34b-3p.
Wang L, Li S, Qi L, Ling L
Mediators of inflammation 2021;2021:9978882
Mediators of inflammation 2021;2021:9978882
Exosomes Containing LINC00636 Inhibit MAPK1 through the miR-450a-2-3p Overexpression in Human Pericardial Fluid and Improve Cardiac Fibrosis in Patients with Atrial Fibrillation.
Liu L, Luo F, Lei K
Mediators of inflammation 2021;2021:9960241
Mediators of inflammation 2021;2021:9960241
TRIM29 Reverses Oxaliplatin Resistance of P53 Mutant Colon Cancer Cell.
Lei G, Liu S, Yang X, He C
Canadian journal of gastroenterology & hepatology 2021;2021:8870907
Canadian journal of gastroenterology & hepatology 2021;2021:8870907
Constitutive Androstane Receptor-Mediated Inhibition of Metformin on Phase II Metabolic Enzyme SULT2A1.
Hu X, Li M, Zhang C, Pang S
International journal of endocrinology 2021;2021:8867218
International journal of endocrinology 2021;2021:8867218
Ze-Qi-Tang Formula Induces Granulocytic Myeloid-Derived Suppressor Cell Apoptosis via STAT3/S100A9/Bcl-2/Caspase-3 Signaling to Prolong the Survival of Mice with Orthotopic Lung Cancer.
Xu ZH, Zhu YZ, Su L, Tang XY, Yao C, Jiao XN, Hou YF, Chen X, Wei LY, Wang WT, Wang J, Gong CY, Zhu XD, Zhang F, Zhu SG, Zou CP
Mediators of inflammation 2021;2021:8856326
Mediators of inflammation 2021;2021:8856326
ADAM17 Mediates Hypoxia-Induced Keratinocyte Migration via the p38/MAPK Pathway.
Zhu G, Liu J, Wang Y, Jia N, Wang W, Zhang J, Liang Y, Tian H, Zhang J
BioMed research international 2021;2021:8328216
BioMed research international 2021;2021:8328216
Catalpol-Induced AMPK Activation Alleviates Cisplatin-Induced Nephrotoxicity through the Mitochondrial-Dependent Pathway without Compromising Its Anticancer Properties.
Zhang J, Zhao T, Wang C, Meng Q, Huo X, Wang C, Sun P, Sun H, Ma X, Wu J, Liu K
Oxidative medicine and cellular longevity 2021;2021:7467156
Oxidative medicine and cellular longevity 2021;2021:7467156
High Methionine Diet-Induced Alzheimer's Disease like Symptoms Are Accompanied by 5-Methylcytosine Elevated Levels in the Brain.
Pi T, Wei S, Jiang Y, Shi JS
Behavioural neurology 2021;2021:6683318
Behavioural neurology 2021;2021:6683318
Neferine Protects against Hypoxic-Ischemic Brain Damage in Neonatal Rats by Suppressing NLRP3-Mediated Inflammasome Activation.
Zhu JJ, Yu BY, Huang XK, He MZ, Chen BW, Chen TT, Fang HY, Chen SQ, Fu XQ, Li PJ, Lin ZL, Zhu JH
Oxidative medicine and cellular longevity 2021;2021:6654954
Oxidative medicine and cellular longevity 2021;2021:6654954
The Regulation of ROS- and BECN1-Mediated Autophagy by Human Telomerase Reverse Transcriptase in Glioblastoma.
Ding X, Nie Z, She Z, Bai X, Yang Q, Wang F, Wang F, Geng X
Oxidative medicine and cellular longevity 2021;2021:6636510
Oxidative medicine and cellular longevity 2021;2021:6636510
Overexpression of RIPK4 Predicts Poor Prognosis and Promotes Metastasis in Ovarian Cancer.
Liu S, He L, Sheng C, Su R, Wu X, Sun Y, Xi X
BioMed research international 2021;2021:6622439
BioMed research international 2021;2021:6622439
Uncovering the Pharmacology of Xiaochaihu Decoction in the Treatment of Acute Pancreatitis Based on the Network Pharmacology.
Zhan L, Pu J, Hu Y, Xu P, Liang W, Ji C
BioMed research international 2021;2021:6621682
BioMed research international 2021;2021:6621682
Taohong Siwu-Containing Serum Enhances Angiogenesis in Rat Aortic Endothelial Cells by Regulating the VHL/HIF-1α/VEGF Signaling Pathway.
Tang Z, Li W, Xie H, Jiang S, Pu Y, Xiong H
Evidence-based complementary and alternative medicine : eCAM 2021;2021:6610116
Evidence-based complementary and alternative medicine : eCAM 2021;2021:6610116
GDF-15 Suppresses Atherosclerosis by Inhibiting oxLDL-Induced Lipid Accumulation and Inflammation in Macrophages.
Huang H, Chen Z, Li Y, Gong K, Xiao L, Fu H, Yang J, Wang X, Meng Q
Evidence-based complementary and alternative medicine : eCAM 2021;2021:6497568
Evidence-based complementary and alternative medicine : eCAM 2021;2021:6497568
Deficiency of MIF Accentuates Overloaded Compression-Induced Nucleus Pulposus Cell Oxidative Damage via Depressing Mitophagy.
Wang Y, Hu Y, Wang H, Liu N, Luo L, Zhao C, Zhou D, Tong H, Li P, Zhou Q
Oxidative medicine and cellular longevity 2021;2021:6192498
Oxidative medicine and cellular longevity 2021;2021:6192498
Epigallocatechin-3-Gallate Alleviates High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease via Inhibition of Apoptosis and Promotion of Autophagy through the ROS/MAPK Signaling Pathway.
Wu D, Liu Z, Wang Y, Zhang Q, Li J, Zhong P, Xie Z, Ji A, Li Y
Oxidative medicine and cellular longevity 2021;2021:5599997
Oxidative medicine and cellular longevity 2021;2021:5599997
EZH2 Mediates miR-146a-5p/HIF-1α to Alleviate Inflammation and Glycolysis after Acute Spinal Cord Injury.
Ni S, Yang B, Xia L, Zhang H
Mediators of inflammation 2021;2021:5591582
Mediators of inflammation 2021;2021:5591582
A Network Pharmacology Approach for Exploring the Mechanisms of Panax notoginseng Saponins in Ischaemic Stroke.
Wang C, Chen H, Ma ST, Mao BB, Chen Y, Xu HN, Yu H
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5582782
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5582782
Inhibition of α-Synuclein Accumulation Improves Neuronal Apoptosis and Delayed Postoperative Cognitive Recovery in Aged Mice.
Li Y, Yuan Y, Li Y, Han D, Liu T, Yang N, Mi X, Hong J, Liu K, Song Y, He J, Zhou Y, Han Y, Shi C, Yu S, Zou P, Guo X, Li Z
Oxidative medicine and cellular longevity 2021;2021:5572899
Oxidative medicine and cellular longevity 2021;2021:5572899
POU2F1 Promotes Cell Viability and Tumor Growth in Gastric Cancer through Transcriptional Activation of lncRNA TTC3-AS1.
Wang J, Xiao K, Hou F, Tang L, Luo D, Liu G, Wang Z
Journal of oncology 2021;2021:5570088
Journal of oncology 2021;2021:5570088
Baihe Jizihuang Tang Ameliorates Chronic Unpredictable Mild Stress-Induced Depression-Like Behavior: Integrating Network Pharmacology and Brain-Gut Axis Evaluation.
Zhu JP, Wu HY, Zi Y, Xia XB, Xie MZ, Yuan ZY
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5554363
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5554363
NOX4-Derived ROS Mediates TGF-β1-Induced Metabolic Reprogramming during Epithelial-Mesenchymal Transition through the PI3K/AKT/HIF-1α Pathway in Glioblastoma.
Su X, Yang Y, Guo C, Zhang R, Sun S, Wang Y, Qiao Q, Fu Y, Pang Q
Oxidative medicine and cellular longevity 2021;2021:5549047
Oxidative medicine and cellular longevity 2021;2021:5549047
Study on the Antitumor Effect and Glycolysis of Andrographolide in Anaplastic Thyroid Carcinoma.
Yang K, Wu K, Feng J, Yutian L, Zhu X, Xu D
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5526581
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5526581
Berbamine Inhibits Cell Proliferation and Migration and Induces Cell Death of Lung Cancer Cells via Regulating c-Maf, PI3K/Akt, and MDM2-P53 Pathways.
Liu L, Xu Z, Yu B, Tao L, Cao Y
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5517143
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5517143
The Key Ingredient Acacetin in Weishu Decoction Alleviates Gastrointestinal Motility Disorder Based on Network Pharmacology Analysis.
Guo X, Xu Y, Tan HL, Wang XJ, Xiao L
Mediators of inflammation 2021;2021:5265444
Mediators of inflammation 2021;2021:5265444
The Effect of miR-520b on Macrophage Polarization and T Cell Immunity by Targeting PTEN in Breast Cancer.
Zhu Q, Yuan J, He Y, Hu Y
Journal of oncology 2021;2021:5170496
Journal of oncology 2021;2021:5170496
OM-MSCs Alleviate the Golgi Apparatus Stress Response following Cerebral Ischemia/Reperfusion Injury via the PEDF-PI3K/Akt/mTOR Signaling Pathway.
He J, Liu J, Huang Y, Tang X, Xiao H, Liu Z, Jiang Z, Zeng L, Hu Z, Lu M
Oxidative medicine and cellular longevity 2021;2021:4805040
Oxidative medicine and cellular longevity 2021;2021:4805040
The Dietary Supplement γ-Oryzanol Attenuates Hepatic Ischemia Reperfusion Injury via Inhibiting Endoplasmic Reticulum Stress and HMGB1/NLRP3 Inflammasome.
Du Y, Zhong F, Cheng H, Li T, Chen Y, Tan P, Huang M, Liang T, Liu Y, Xia X, Fu W
Oxidative medicine and cellular longevity 2021;2021:4628050
Oxidative medicine and cellular longevity 2021;2021:4628050
Ameliorative Effects and Mechanism of Buyang Huanwu Decoction on Pulmonary Vascular Remodeling: Network and Experimental Analyses.
Chen Y, Cui L, Wang C, Liu J, Guo J
Oxidative medicine and cellular longevity 2021;2021:4576071
Oxidative medicine and cellular longevity 2021;2021:4576071
Comparative Efficacy of Haizao Yuhu Decoction Composed of Different Varieties of Glycyrrhiza in Goiter Rats.
Chen F, Li N, Xiu L, Liu H, Chen S, He C, Fan A, Yu X, Wang X, Ge C, Huo M, He J, Zhong G
Evidence-based complementary and alternative medicine : eCAM 2021;2021:4343239
Evidence-based complementary and alternative medicine : eCAM 2021;2021:4343239
Zinc Regulates Glucose Metabolism of the Spinal Cord and Neurons and Promotes Functional Recovery after Spinal Cord Injury through the AMPK Signaling Pathway.
Hu H, Xia N, Lin J, Li D, Zhang C, Ge M, Tian H, Mei X
Oxidative medicine and cellular longevity 2021;2021:4331625
Oxidative medicine and cellular longevity 2021;2021:4331625
Nrf2 Pathway Ameliorates Bladder Dysfunction in Cyclophosphamide-Induced Cystitis via Suppression of Oxidative Stress.
Ni B, Chen Z, Shu L, Shao Y, Huang Y, Tamrat NE, Wei Z, Shen B
Oxidative medicine and cellular longevity 2021;2021:4009308
Oxidative medicine and cellular longevity 2021;2021:4009308
Chlorogenic Acid Alleviates Colon Mucosal Damage Induced by a High-Fat Diet via Gut Microflora Adjustment to Increase Short-Chain Fatty Acid Accumulation in Rats.
Xie MG, Fei YQ, Wang Y, Wang WY, Wang Z
Oxidative medicine and cellular longevity 2021;2021:3456542
Oxidative medicine and cellular longevity 2021;2021:3456542
Electroacupuncture Ameliorates Depression-Like Behaviour in Rats by Enhancing Synaptic Plasticity via the GluN2B/CaMKII/CREB Signalling Pathway.
Zhang K, Liu R, Zhang J, Wei X, Gao Y, Ma W, Li Y, Cai W, Shen W
Evidence-based complementary and alternative medicine : eCAM 2021;2021:2146001
Evidence-based complementary and alternative medicine : eCAM 2021;2021:2146001
Inhibition of the PERK/TXNIP/NLRP3 Axis by Baicalin Reduces NLRP3 Inflammasome-Mediated Pyroptosis in Macrophages Infected with Mycobacterium tuberculosis.
Fu Y, Shen J, Li Y, Liu F, Ning B, Zheng Y, Jiang X
Mediators of inflammation 2021;2021:1805147
Mediators of inflammation 2021;2021:1805147
Microglia-Derived Exosomes Improve Spinal Cord Functional Recovery after Injury via Inhibiting Oxidative Stress and Promoting the Survival and Function of Endothelia Cells.
Peng W, Wan L, Luo Z, Xie Y, Liu Y, Huang T, Lu H, Hu J
Oxidative medicine and cellular longevity 2021;2021:1695087
Oxidative medicine and cellular longevity 2021;2021:1695087
Inhibiting PP2Acα Promotes the Malignant Phenotype of Gastric Cancer Cells through the ATM/METTL3 Axis.
Cheng Z, Gao S, Liang X, Lian C, Chen J, Fang C
BioMed research international 2021;2021:1015293
BioMed research international 2021;2021:1015293
Qingda granule exerts neuroprotective effects against ischemia/reperfusion-induced cerebral injury via lncRNA GAS5/miR-137 signaling pathway.
Zhang L, Cai Q, Lin S, Chen B, Jia B, Ye R, Weygant N, Chu J, Peng J
International journal of medical sciences 2021;18(7):1687-1698
International journal of medical sciences 2021;18(7):1687-1698
NSE, positively regulated by LINC00657-miR-93-5p axis, promotes small cell lung cancer (SCLC) invasion and epithelial-mesenchymal transition (EMT) process.
Lu L, Zha Z, Zhang P, Li D, Liu G
International journal of medical sciences 2021;18(16):3768-3779
International journal of medical sciences 2021;18(16):3768-3779
Simultaneous silencing Aurora-A and UHRF1 inhibits colorectal cancer cell growth through regulating expression of DNMT1 and STAT1.
Han J, Chen X, Xu J, Chu L, Li R, Sun N, Jiang Z, Liu H, Ge X, Zheng J, Yang J, Ikezoe T
International journal of medical sciences 2021;18(15):3437-3451
International journal of medical sciences 2021;18(15):3437-3451
GABAB receptor inhibits tumor progression and epithelial-mesenchymal transition via the regulation of Hippo/YAP1 pathway in colorectal cancer.
Wang H, Zhang H, Sun Z, Chen W, Miao C
International journal of biological sciences 2021;17(8):1953-1962
International journal of biological sciences 2021;17(8):1953-1962
Macrophage migration inhibitory factor regulates joint capsule fibrosis by promoting TGF-β1 production in fibroblasts.
Zhang Y, Liu Z, Wang K, Lu S, Fan S, Xu L, Cai B
International journal of biological sciences 2021;17(7):1837-1850
International journal of biological sciences 2021;17(7):1837-1850
Aurka deficiency in the intestinal epithelium promotes age-induced obesity via propionate-mediated AKT activation.
Sun N, Meng F, Zhao J, Li X, Li R, Han J, Chen X, Cheng W, Yang X, Kou Y, Zheng K, Yang J, Ikezoe T
International journal of biological sciences 2021;17(5):1302-1314
International journal of biological sciences 2021;17(5):1302-1314
Targeting HLA-F suppresses the proliferation of glioma cells via a reduction in hexokinase 2-dependent glycolysis.
Chen X, Sun N, Li R, Sang X, Li X, Zhao J, Han J, Yang J, Ikezoe T
International journal of biological sciences 2021;17(5):1263-1276
International journal of biological sciences 2021;17(5):1263-1276
FOXM1-induced miR-552 expression contributes to pancreatic cancer progression by targeting multiple tumor suppressor genes.
Wang X, Dou N, Wang J, Zhang Y, Li Y, Gao Y
International journal of biological sciences 2021;17(4):915-925
International journal of biological sciences 2021;17(4):915-925
AKR1B10 confers resistance to radiotherapy via FFA/TLR4/NF-κB axis in nasopharyngeal carcinoma.
Liu X, Hu Z, Qu J, Li J, Gong K, Wang L, Jiang J, Li X, He R, Duan L, Luo W, Xia C, Luo D
International journal of biological sciences 2021;17(3):756-767
International journal of biological sciences 2021;17(3):756-767
SOCS2 Suppresses Inflammation and Apoptosis during NASH Progression through Limiting NF-κB Activation in Macrophages.
Li S, Han S, Jin K, Yu T, Chen H, Zhou X, Tan Z, Zhang G
International journal of biological sciences 2021;17(15):4165-4175
International journal of biological sciences 2021;17(15):4165-4175
KMT5A downregulation participated in High Glucose-mediated EndMT via Upregulation of ENO1 Expression in Diabetic Nephropathy.
Lu L, Li X, Zhong Z, Zhou W, Zhou D, Zhu M, Miao C
International journal of biological sciences 2021;17(15):4093-4107
International journal of biological sciences 2021;17(15):4093-4107
The imbalance of PGD2-DPs pathway is involved in the type 2 diabetes brain injury by regulating autophagy.
Yang Y, Xiang P, Chen Q, Luo Y, Wang H, Li H, Yang L, Hu C, Zhang J, Li Y, Xia H, Chen Z, Yang J
International journal of biological sciences 2021;17(14):3993-4004
International journal of biological sciences 2021;17(14):3993-4004
Discovery of a novel HDACi structure that inhibits the proliferation of ovarian cancer cells in vivo and in vitro.
Bai M, Cui M, Li M, Yao X, Wu Y, Zheng L, Sun L, Song Q, Wang S, Liu L, Yu C, Huang Y
International journal of biological sciences 2021;17(13):3493-3507
International journal of biological sciences 2021;17(13):3493-3507
Deubiquitinase PSMD7 promotes the proliferation, invasion, and cisplatin resistance of gastric cancer cells by stabilizing RAD23B.
Wang J, Liu R, Mo H, Xiao X, Xu Q, Zhao W
International journal of biological sciences 2021;17(13):3331-3342
International journal of biological sciences 2021;17(13):3331-3342
NCTD Prevents Renal Interstitial Fibrosis via Targeting Sp1/lncRNA Gm26669 Axis.
Tian J, Xiao Z, Wei J, Shan Y, Zeng D, Tao Y, Fang X, Tang C, Chen X, Li Y
International journal of biological sciences 2021;17(12):3118-3132
International journal of biological sciences 2021;17(12):3118-3132
H2O2 gel bleaching induces cytotoxicity and pain conduction in dental pulp stem cells via intracellular reactive oxygen species on enamel/dentin disc.
Chen C, Huang X, Zhu W, Ding C, Huang P, Li R
PloS one 2021;16(9):e0257221
PloS one 2021;16(9):e0257221
Chirality and asymmetry increase the potency of candidate ADRM1/RPN13 inhibitors.
Anchoori RK, George L, Tseng SH, Lam B, Polkampally S, Amiano AD, Foran P, Tsingine H, Samanapally H, Carrizo Velasquez F, Das S, Xing D, Bin Salam A, Karanam B, Hung CF, Roden RBS
PloS one 2021;16(9):e0256937
PloS one 2021;16(9):e0256937
Harmine inhibits breast cancer cell migration and invasion by inducing the degradation of Twist1.
Nafie E, Lolarga J, Lam B, Guo J, Abdollahzadeh E, Rodriguez S, Glackin C, Liu J
PloS one 2021;16(2):e0247652
PloS one 2021;16(2):e0247652
Systematic identification of autophagy-related proteins in Aedes albopictus.
Wang Y, Qiao J, Zhang D, Zhong C, Wang S, Li X, Feng L, Shi S, Wang B, Liu Q
PloS one 2021;16(1):e0245694
PloS one 2021;16(1):e0245694
Accurately Controlled Delivery of Temozolomide by Biocompatible UiO-66-NH2 Through Ultrasound to Enhance the Antitumor Efficacy and Attenuate the Toxicity for Treatment of Malignant Glioma.
Wan Z, Li C, Gu J, Qian J, Zhu J, Wang J, Li Y, Jiang J, Chen H, Luo C
International journal of nanomedicine 2021;16:6905-6922
International journal of nanomedicine 2021;16:6905-6922
Photobiomodulation Promotes Repair Following Spinal Cord Injury by Regulating the Transformation of A1/A2 Reactive Astrocytes.
Wang X, Zhang Z, Zhu Z, Liang Z, Zuo X, Ju C, Song Z, Li X, Hu X, Wang Z
Frontiers in neuroscience 2021;15:768262
Frontiers in neuroscience 2021;15:768262
5-HT7 Receptor Is Involved in Electroacupuncture Inhibition of Chronic Pain in the Spinal Cord.
Yuan XC, Yan XJ, Tian LX, Guo YX, Zhao YL, Baba SS, Wang YY, Liang LL, Jia H, Xu LP, Li L, Lin H, Huo FQ
Frontiers in neuroscience 2021;15:733779
Frontiers in neuroscience 2021;15:733779
IL-17 Inhibits Oligodendrocyte Progenitor Cell Proliferation and Differentiation by Increasing K+ Channel Kv1.3.
Liu H, Yang X, Yang J, Yuan Y, Wang Y, Zhang R, Xiong H, Xu Y
Frontiers in cellular neuroscience 2021;15:679413
Frontiers in cellular neuroscience 2021;15:679413
Injection of Anti-proBDNF Attenuates Hippocampal-Dependent Learning and Memory Dysfunction in Mice With Sepsis-Associated Encephalopathy.
Cui YH, Zhou SF, Liu Y, Wang S, Li F, Dai RP, Hu ZL, Li CQ
Frontiers in neuroscience 2021;15:665757
Frontiers in neuroscience 2021;15:665757
Tetramethylpyrazine Alleviates Behavioral and Psychological Symptoms of Dementia Through Facilitating Hippocampal Synaptic Plasticity in Rats With Chronic Cerebral Hypoperfusion.
Tan Z, Qiu J, Zhang Y, Yang Q, Yin X, Li J, Liu G, Li H, Yang G
Frontiers in neuroscience 2021;15:646537
Frontiers in neuroscience 2021;15:646537
Dl-3-n-Butylphthalide Reduces Cognitive Deficits and Alleviates Neuropathology in P301S Tau Transgenic Mice.
Chang Y, Yao Y, Ma R, Wang Z, Hu J, Wu Y, Jiang X, Li L, Li G
Frontiers in neuroscience 2021;15:620176
Frontiers in neuroscience 2021;15:620176
IRE1α-XBP1 Affects the Mitochondrial Function of Aβ25-35-Treated SH-SY5Y Cells by Regulating Mitochondria-Associated Endoplasmic Reticulum Membranes.
Chu B, Li M, Cao X, Li R, Jin S, Yang H, Xu L, Wang P, Bi J
Frontiers in cellular neuroscience 2021;15:614556
Frontiers in cellular neuroscience 2021;15:614556
Doxazosin Attenuates Liver Fibrosis by Inhibiting Autophagy in Hepatic Stellate Cells via Activation of the PI3K/Akt/mTOR Signaling Pathway.
Xiu AY, Ding Q, Li Z, Zhang CQ
Drug design, development and therapy 2021;15:3643-3659
Drug design, development and therapy 2021;15:3643-3659
Baicalin Alleviates Oxidative Stress and Inflammation in Diabetic Nephropathy via Nrf2 and MAPK Signaling Pathway.
Ma L, Wu F, Shao Q, Chen G, Xu L, Lu F
Drug design, development and therapy 2021;15:3207-3221
Drug design, development and therapy 2021;15:3207-3221
Selective Inhibition of 11β-Hydroxysteroid Dehydrogenase Type 1 Attenuates High-Fat Diet-Induced Hepatic Steatosis in Mice.
Li H, Sheng J, Wang J, Gao H, Yu J, Ding G, Ding N, He W, Zha J
Drug design, development and therapy 2021;15:2309-2324
Drug design, development and therapy 2021;15:2309-2324
ADAM17 and NF-κB p65 form a positive feedback loop that facilitates human esophageal squamous cell carcinoma cell viability.
Gao L, Liu H, Xu R, Qiu J, Peng X, Yang Y, Zhang D, Qian J
International journal of clinical and experimental pathology 2021;14(7):845-854
International journal of clinical and experimental pathology 2021;14(7):845-854
Gαi1 Promoted Proliferation, Migration and Invasion via Activating the Akt-mTOR/Erk-MAPK Signaling Pathway in Renal Cell Carcinoma.
Chen Z, Zhang Y, Wu X, Zhang J, Xu W, Shen C, Zheng B
OncoTargets and therapy 2021;14:2941-2952
OncoTargets and therapy 2021;14:2941-2952
Regulation of IFN-Is by MEF2D Promotes Inflammatory Homeostasis in Microglia.
Lu F, Wang R, Xia L, Nie T, Gao F, Yang S, Huang L, Shao K, Liu J, Yang Q
Journal of inflammation research 2021;14:2851-2863
Journal of inflammation research 2021;14:2851-2863
GADD45B Facilitates Metastasis of Ovarian Cancer Through Epithelial-Mesenchymal Transition.
Gong L, Cai L, Li G, Cai J, Yi X
OncoTargets and therapy 2021;14:255-269
OncoTargets and therapy 2021;14:255-269
Upregulation of Neuronal Cylindromatosis Expression is Essential for Electroacupuncture-Mediated Alleviation of Neuroinflammatory Injury by Regulating Microglial Polarization in Rats Subjected to Focal Cerebral Ischemia/Reperfusion.
Lin X, Zhan J, Jiang J, Ren Y
Journal of inflammation research 2021;14:2061-2078
Journal of inflammation research 2021;14:2061-2078
Orexin-A Attenuates Inflammatory Responses in Lipopolysaccharide-Induced Neural Stem Cells by Regulating NF-KB and Phosphorylation of MAPK/P38/Erk Pathways.
Ye W, Yan Y, Tang Y, Dong X, Chen G, Kang J, Huang L, Xiong Q, Feng Z
Journal of inflammation research 2021;14:2007-2017
Journal of inflammation research 2021;14:2007-2017
MiRNA-223-3p Affects Mantle Cell Lymphoma Development by Regulating the CHUK/NF-ƘB2 Signaling Pathway.
Yuan J, Zhang Q, Wu S, Yan S, Zhao R, Sun Y, Tian X, Zhou K
OncoTargets and therapy 2021;14:1553-1564
OncoTargets and therapy 2021;14:1553-1564
The Significance of HOXC11 and LSH in Survival Prediction in Gastric Adenocarcinoma.
Peng X, Sun J, Long Y, Xiao D, Zhou J, Tao Y, Liu S
OncoTargets and therapy 2021;14:1517-1529
OncoTargets and therapy 2021;14:1517-1529
Network pharmacology-guided mechanism study uncovers inhibitory effect of Mahuang Decoction on lung cancer growth by impeding Akt/ERK signaling pathways.
Pan Y, Chen Y, Wu C, Ai J, Wang Y, Jia J, Liu L
American journal of translational research 2021;13(4):2094-2110
American journal of translational research 2021;13(4):2094-2110
Sevoflurane prevents pulmonary vascular remodeling and right ventricular dysfunction in pulmonary arterial hypertension in rats.
Zhai W, Li Y, Luo Y, Gao W, Liu S, Han J, Geng J
American journal of translational research 2021;13(10):11302-11315
American journal of translational research 2021;13(10):11302-11315
Dura cells in the etiopathogenesis of Crouzon syndrome: the effects of FGFR2 mutations in the dura cells on the proliferation of osteoblasts through the hippo/YAP mediated transcriptional regulation pathway.
Dong XH, Zhang MZ, Lai CZ, Li CC, Du L, Song GD, Zong XL, Jin XL
American journal of translational research 2021;13(10):11255-11270
American journal of translational research 2021;13(10):11255-11270
Schisandrin C attenuates renal damage in diabetic nephropathy by regulating macrophage polarization.
Wang Y, Cui J, Liu M, Shao Y, Dong X
American journal of translational research 2021;13(1):210-222
American journal of translational research 2021;13(1):210-222
Overexpression of the lncRNA AC012213.3 Promotes Proliferation, Migration and Invasion of Breast Cancer via RAD54B/PI3K/AKT Axis and is Associated with Worse Patient Prognosis.
Zhong H, Zeng G, He L
Cancer management and research 2021;13:7213-7223
Cancer management and research 2021;13:7213-7223
LncRNA TMEM220-AS1 suppresses hepatocellular carcinoma cell proliferation and invasion by regulating the TMEM220/β-catenin axis.
Liu Y, Liu R, Zhao J, Zeng Z, Shi Z, Lu Q, Guo J, Li L, Yao Y, Liu X, Xu Q
Journal of Cancer 2021;12(22):6805-6813
Journal of Cancer 2021;12(22):6805-6813
LncRNA MALAT1 was regulated by HPV16 E7 independently of pRB in cervical cancer cells.
Wang T, Zhang W, Huang W, Hua Z, Li S
Journal of Cancer 2021;12(21):6344-6355
Journal of Cancer 2021;12(21):6344-6355
Inositol hexaphosphate sensitizes hepatocellular carcinoma to oxaliplatin relating inhibition of CCN2-LRP6-β-catenin-ABCG1 signaling pathway.
Liao X, Zhang Y, Xu B, Ali A, Liu X, Jia Q
Journal of Cancer 2021;12(20):6071-6080
Journal of Cancer 2021;12(20):6071-6080
Caspase-11-Mediated Hepatocytic Pyroptosis Promotes the Progression of Nonalcoholic Steatohepatitis.
Zhu Y, Zhao H, Lu J, Lin K, Ni J, Wu G, Tang H
Cellular and molecular gastroenterology and hepatology 2021;12(2):653-664
Cellular and molecular gastroenterology and hepatology 2021;12(2):653-664
SLC39A7 promotes malignant behaviors in glioma via the TNF-α-mediated NF-κB signaling pathway.
Chen L, Zhou J, Li L, Zhao J, Li H, Zheng W, Xu J, Jing Z
Journal of Cancer 2021;12(15):4530-4541
Journal of Cancer 2021;12(15):4530-4541
Demethylzelasteral inhibits proliferation and EMT via repressing Wnt/β-catenin signaling in esophageal squamous cell carcinoma.
Yu J, Wang W, Liu B, Gu J, Chen S, Cui Y, Sun G
Journal of Cancer 2021;12(13):3967-3975
Journal of Cancer 2021;12(13):3967-3975
CDK5 Knockdown inhibits proliferation and induces apoptosis and Cell Cycle Arrest in Human Glioblastoma.
Zhou Y, Wang X, Lv P, Yu H, Jiang X
Journal of Cancer 2021;12(13):3958-3966
Journal of Cancer 2021;12(13):3958-3966
Punicalin Attenuates Breast Cancer-Associated Osteolysis by Inhibiting the NF-κB Signaling Pathway of Osteoclasts.
Li T, Jiang G, Hu X, Yang D, Tan T, Gao Z, Chen Z, Xiang C, Li S, Ouyang Z, Guo X
Frontiers in pharmacology 2021;12:789552
Frontiers in pharmacology 2021;12:789552
CircEpc1 Promotes Ricin Toxin-Induced Inflammation via Activation of NF-κB and MAPK Signaling Pathways by Sponging miR-5114.
Dong M, Zhang X, Yu H, Wang Y, Chang Y, Sun C, Zhang J, Zhao N, Yu K, Sun G, Zhao G, Xu N, Liu W
Frontiers in pharmacology 2021;12:767900
Frontiers in pharmacology 2021;12:767900
Trametinib Inhibits the Growth and Aerobic Glycolysis of Glioma Cells by Targeting the PKM2/c-Myc Axis.
Gao M, Yang J, Gong H, Lin Y, Liu J
Frontiers in pharmacology 2021;12:760055
Frontiers in pharmacology 2021;12:760055
The Effect of Ellagic Acid on Hepatic Lipid Metabolism and Antioxidant Activity in Mice.
Xu Q, Li S, Tang W, Yan J, Wei X, Zhou M, Diao H
Frontiers in physiology 2021;12:751501
Frontiers in physiology 2021;12:751501
SARS-CoV-2 Nsp5 Activates NF-κB Pathway by Upregulating SUMOylation of MAVS.
Li W, Qiao J, You Q, Zong S, Peng Q, Liu Y, Hu S, Liu W, Li S, Shu X, Sun B
Frontiers in immunology 2021;12:750969
Frontiers in immunology 2021;12:750969
Rhein Relieves Oxidative Stress in an Aβ(1-42) Oligomer-Burdened Neuron Model by Activating the SIRT1/PGC-1α-Regulated Mitochondrial Biogenesis.
Yin Z, Geng X, Zhang Z, Wang Y, Gao X
Frontiers in pharmacology 2021;12:746711
Frontiers in pharmacology 2021;12:746711
Anlotinib Inhibits PFKFB3-Driven Glycolysis in Myofibroblasts to Reverse Pulmonary Fibrosis.
Chen W, Zhang J, Zhong W, Liu Y, Lu Y, Zeng Z, Huang H, Wan X, Meng X, Zou F, Cai S, Dong H
Frontiers in pharmacology 2021;12:744826
Frontiers in pharmacology 2021;12:744826
Identification of a Novel Gene Correlated With Vascular Smooth Muscle Cells Proliferation and Migration in Chronic Thromboembolic Pulmonary Hypertension.
Wang F, Sun C, Lv X, Sun M, Si C, Zhen Y, Guo J, Sun W, Ye Z, Wen J, Liu P
Frontiers in physiology 2021;12:744219
Frontiers in physiology 2021;12:744219
Morchella importuna Flavones Improve Intestinal Integrity in Dextran Sulfate Sodium-Challenged Mice.
Xu Y, Xie L, Tang J, He X, Zhang Z, Chen Y, Zhou J, Gan B, Peng W
Frontiers in microbiology 2021;12:742033
Frontiers in microbiology 2021;12:742033
Probiotic Interventions Alleviate Food Allergy Symptoms Correlated With Cesarean Section: A Murine Model.
Jin BY, Li Z, Xia YN, Li LX, Zhao ZX, Li XY, Li Y, Li B, Zhou RC, Fu SC, Li SY, Li YQ
Frontiers in immunology 2021;12:741371
Frontiers in immunology 2021;12:741371
Paeoniflorin Suppresses TBHP-Induced Oxidative Stress and Apoptosis in Human Umbilical Vein Endothelial Cells via the Nrf2/HO-1 Signaling Pathway and Improves Skin Flap Survival.
Jiang J, Dong C, Zhai L, Lou J, Jin J, Cheng S, Chen Z, Guo X, Lin D, Ding J, Gao W
Frontiers in pharmacology 2021;12:735530
Frontiers in pharmacology 2021;12:735530
Polysaccharides Extracted From Panax Ginseng C.A. Mey Enhance Complement Component 4 Biosynthesis in Human Hepatocytes.
Liu S, Liu F, Wang T, Liu J, Hu C, Sun L, Wang G
Frontiers in pharmacology 2021;12:734394
Frontiers in pharmacology 2021;12:734394
Association of Pericyte Loss With Microthrombosis After Subarachnoid Hemorrhage in ApoE-Deficient Mice.
Pang J, Wu Y, Peng J, Yang P, Chen L, Jiang Y
Frontiers in neurology 2021;12:726520
Frontiers in neurology 2021;12:726520
Identification of Potential Prognostic Biomarker for Predicting Survival in Multiple Myeloma Using Bioinformatics Analysis and Experiments.
Zhou J, Zhang M, Zhang Y, Shi X, Liu L, Yao R
Frontiers in genetics 2021;12:722132
Frontiers in genetics 2021;12:722132
The Downregulation of eIF3a Contributes to Vemurafenib Resistance in Melanoma by Activating ERK via PPP2R1B.
Jiang SL, Wang ZB, Zhu T, Jiang T, Fei JF, Liu C, Luo C, Cheng Y, Liu ZQ
Frontiers in pharmacology 2021;12:720619
Frontiers in pharmacology 2021;12:720619
Inhibition of the Inflammasome Activity of NLRP3 Attenuates HDM-Induced Allergic Asthma.
Ma M, Li G, Qi M, Jiang W, Zhou R
Frontiers in immunology 2021;12:718779
Frontiers in immunology 2021;12:718779
Weighted Gene Co-Expression Network Analysis Identifies ANGPTL4 as a Key Regulator in Diabetic Cardiomyopathy via FAK/SIRT3/ROS Pathway in Cardiomyocyte.
Dai L, Xie Y, Zhang W, Zhong X, Wang M, Jiang H, He Z, Liu X, Zeng H, Wang H
Frontiers in endocrinology 2021;12:705154
Frontiers in endocrinology 2021;12:705154
Novel Pyrazolo[3,4-b] Pyridine Derivative (HLQ2g) Attenuates Hypoxic Pulmonary Hypertension via Restoring cGKI Expression and BMP Signaling Pathway.
Li L, Yin M, Hu L, Tian X, He X, Zhao C, Li Y, Li Q, Li X
Frontiers in pharmacology 2021;12:691405
Frontiers in pharmacology 2021;12:691405
miR-25 Regulates Gastric Cancer Cell Growth and Apoptosis by Targeting EGR2.
Yang L, Li L, Chang P, Wei M, Chen J, Zhu C, Jia J
Frontiers in genetics 2021;12:690196
Frontiers in genetics 2021;12:690196
An Escherichia coli Effector Protein EspF May Induce Host DNA Damage via Interaction With SMC1.
Fu M, Liang S, Wu J, Hua Y, Chen H, Zhang Z, Liu J, Li X, Zhang B, Zhao W, Wan C
Frontiers in microbiology 2021;12:682064
Frontiers in microbiology 2021;12:682064
Lidocaine Promoted Ferroptosis by Targeting miR-382-5p /SLC7A11 Axis in Ovarian and Breast Cancer.
Sun D, Li YC, Zhang XY
Frontiers in pharmacology 2021;12:681223
Frontiers in pharmacology 2021;12:681223
Autophagy is Involved in Neuroprotective Effect of Alpha7 Nicotinic Acetylcholine Receptor on Ischemic Stroke.
Xu ZQ, Zhang JJ, Kong N, Zhang GY, Ke P, Han T, Su DF, Liu C
Frontiers in pharmacology 2021;12:676589
Frontiers in pharmacology 2021;12:676589
c-Myc Upregulated by High Glucose Inhibits HaCaT Differentiation by S100A6 Transcriptional Activation.
Zhang J, Yang P, Liu D, Gao M, Wang J, Wang X, Liu Y, Zhang X
Frontiers in endocrinology 2021;12:676403
Frontiers in endocrinology 2021;12:676403
High Mobility Group Box 1 (HMGB1) Induces Toll-Like Receptor 4-Mediated Production of the Immunosuppressive Protein Galectin-9 in Human Cancer Cells.
Teo Hansen Selnø A, Schlichtner S, Yasinska IM, Sakhnevych SS, Fiedler W, Wellbrock J, Berger SM, Klenova E, Gibbs BF, Fasler-Kan E, Sumbayev VV
Frontiers in immunology 2021;12:675731
Frontiers in immunology 2021;12:675731
Effects of Sodium Ferulate on Cardiac Hypertrophy Are via the CaSR-Mediated Signaling Pathway.
Chen P, Wen Z, Shi W, Li Z, Chen X, Gao Y, Xu S, Gong Q, Deng J
Frontiers in pharmacology 2021;12:674570
Frontiers in pharmacology 2021;12:674570
SARS-CoV-2 Membrane Protein Inhibits Type I Interferon Production Through Ubiquitin-Mediated Degradation of TBK1.
Sui L, Zhao Y, Wang W, Wu P, Wang Z, Yu Y, Hou Z, Tan G, Liu Q
Frontiers in immunology 2021;12:662989
Frontiers in immunology 2021;12:662989
Astragaloside IV Inhibits Galactose-Deficient IgA1 Secretion via miR-98-5p in Pediatric IgA Nephropathy.
Liu C, Li X, Shuai L, Dang X, Peng F, Zhao M, Xiong S, Liu Y, He Q
Frontiers in pharmacology 2021;12:658236
Frontiers in pharmacology 2021;12:658236
Circ_0040039 May Aggravate Intervertebral Disk Degeneration by Regulating the MiR-874-3p-ESR1 Pathway.
Li Y, Wang X, Xu H, Li G, Huo Z, Du L, Zhang K, Shen L, Li H, Xu B
Frontiers in genetics 2021;12:656759
Frontiers in genetics 2021;12:656759
A New Chalcone Derivative C49 Reverses Doxorubicin Resistance in MCF-7/DOX Cells by Inhibiting P-Glycoprotein Expression.
Wang T, Dong J, Yuan X, Wen H, Wu L, Liu J, Sui H, Deng W
Frontiers in pharmacology 2021;12:653306
Frontiers in pharmacology 2021;12:653306
Nicotine Causes Mitochondrial Dynamics Imbalance and Apoptosis Through ROS Mediated Mitophagy Impairment in Cardiomyocytes.
Meng TT, Wang W, Meng FL, Wang SY, Wu HH, Chen JM, Zheng Y, Wang GX, Zhang MX, Li Y, Su GH
Frontiers in physiology 2021;12:650055
Frontiers in physiology 2021;12:650055
Quercetin Attenuates Trauma-Induced Heterotopic Ossification by Tuning Immune Cell Infiltration and Related Inflammatory Insult.
Li J, Sun Z, Luo G, Wang S, Cui H, Yao Z, Xiong H, He Y, Qian Y, Fan C
Frontiers in immunology 2021;12:649285
Frontiers in immunology 2021;12:649285
TOX Acts as a Tumor Suppressor by Inhibiting mTOR Signaling in Colorectal Cancer.
Yang M, Huang Q, Li C, Jiang Z, Sun J, Wang Z, Liang R, Li D, Li B, Zhao H
Frontiers in immunology 2021;12:647540
Frontiers in immunology 2021;12:647540
Identification of a RAD52 Inhibitor Inducing Synthetic Lethality in BRCA2-Deficient Cancer Cells.
Yang Q, Li Y, Sun R, Li J
Frontiers in pharmacology 2021;12:637825
Frontiers in pharmacology 2021;12:637825
BYHWD Alleviates Inflammatory Response by NIK-Mediated Repression of the Noncanonical NF-κB Pathway During ICH Recovery.
Xiao W, He Z, Luo W, Feng D, Wang Y, Tang T, Yang A, Luo J
Frontiers in pharmacology 2021;12:632407
Frontiers in pharmacology 2021;12:632407
Increased Angiogenin Expression Correlates With Radiation Resistance and Predicts Poor Survival for Patients With Nasopharyngeal Carcinoma.
Guo SS, Liang YJ, Liu LT, Chen QY, Wen YF, Liu SL, Sun XS, Tang QN, Li XY, Mai HQ, Tang LQ
Frontiers in pharmacology 2021;12:627935
Frontiers in pharmacology 2021;12:627935
Meteorin-Like Ameliorates β Cell Function by Inhibiting β Cell Apoptosis of and Promoting β Cell Proliferation via Activating the WNT/β-Catenin Pathway.
Hu W, Wang R, Sun B
Frontiers in pharmacology 2021;12:627147
Frontiers in pharmacology 2021;12:627147
Duck Hepatitis A Virus Type 1 Induces eIF2α Phosphorylation-Dependent Cellular Translation Shutoff via PERK/GCN2.
Liu Y, Cheng A, Wang M, Mao S, Ou X, Yang Q, Wu Y, Gao Q, Liu M, Zhang S, Huang J, Jia R, Zhu D, Chen S, Zhao X, Yu Y, Liu Y, Zhang L, Tian B, Pan L
Frontiers in microbiology 2021;12:624540
Frontiers in microbiology 2021;12:624540
In Vivo Inhibition of MicroRNA-326 in a NOD.H-2h4 Mouse Model of Autoimmune Thyroiditis.
Zhao N, Wang Z, Cui X, Wang S, Fan C, Li Y, Shan Z, Teng W
Frontiers in immunology 2021;12:620916
Frontiers in immunology 2021;12:620916
IR-61 Improves Voiding Function via Mitochondrial Protection in Diabetic Rats.
Wang J, Dai L, Yue X, Shen C, Li T, Long L, Zhi Y, Wang Y, Shen G, Shi C, Liu Y, Fang Q, Li W
Frontiers in pharmacology 2021;12:608637
Frontiers in pharmacology 2021;12:608637
Bortezomib Sustains T Cell Function by Inducing miR-155-Mediated Downregulation of SOCS1 and SHIP1.
Renrick AN, Thounaojam MC, de Aquino MTP, Chaudhuri E, Pandhare J, Dash C, Shanker A
Frontiers in immunology 2021;12:607044
Frontiers in immunology 2021;12:607044
Inhibition of Shear-Induced Platelet Aggregation by Xueshuantong via Targeting Piezo1 Channel-Mediated Ca2+ Signaling Pathway.
Liu L, Zhang Q, Xiao S, Sun Z, Ding S, Chen Y, Wang L, Yin X, Liao F, Jiang LH, Xue M, You Y
Frontiers in pharmacology 2021;12:606245
Frontiers in pharmacology 2021;12:606245
SFTSV Infection Induced Interleukin-1β Secretion Through NLRP3 Inflammasome Activation.
Liu JW, Chu M, Jiao YJ, Zhou CM, Qi R, Yu XJ
Frontiers in immunology 2021;12:595140
Frontiers in immunology 2021;12:595140
PHB2 promotes tumorigenesis via RACK1 in non-small cell lung cancer.
Wu B, Chang N, Xi H, Xiong J, Zhou Y, Wu Y, Wu S, Wang N, Yi H, Song Y, Chen L, Zhang J
Theranostics 2021;11(7):3150-3166
Theranostics 2021;11(7):3150-3166
Necroptosis pathway blockage attenuates PFKFB3 inhibitor-induced cell viability loss and genome instability in colorectal cancer cells.
Yan S, Li Q, Zhang D, Wang X, Xu Y, Zhang C, Guo D, Bao Y
American journal of cancer research 2021;11(5):2062-2080
American journal of cancer research 2021;11(5):2062-2080
Targeting of glioma stem-like cells with a parthenolide derivative ACT001 through inhibition of AEBP1/PI3K/AKT signaling.
Hou Y, Sun B, Liu W, Yu B, Shi Q, Luo F, Bai Y, Feng H
Theranostics 2021;11(2):555-566
Theranostics 2021;11(2):555-566
Local administration of liposomal-based Srpx2 gene therapy reverses pulmonary fibrosis by blockading fibroblast-to-myofibroblast transition.
Wang Q, Liu J, Hu Y, Pan T, Xu Y, Yu J, Xiong W, Zhou Q, Wang Y
Theranostics 2021;11(14):7110-7125
Theranostics 2021;11(14):7110-7125
KAT6A, a novel regulator of β-catenin, promotes tumorigenicity and chemoresistance in ovarian cancer by acetylating COP1.
Liu W, Zhan Z, Zhang M, Sun B, Shi Q, Luo F, Zhang M, Zhang W, Hou Y, Xiao X, Li Y, Feng H
Theranostics 2021;11(13):6278-6292
Theranostics 2021;11(13):6278-6292
Aurka loss in CD19+ B cells promotes megakaryocytopoiesis via IL-6/STAT3 signaling-mediated thrombopoietin production.
Chen X, Wang C, Sun N, Pan S, Li R, Li X, Zhao J, Tong H, Tang Y, Han J, Qiao J, Qiu H, Wang H, Yang J, Ikezoe T
Theranostics 2021;11(10):4655-4671
Theranostics 2021;11(10):4655-4671
Ese-3 contributes to colon cancer progression by downregulating EHD2 and transactivating INPP4B.
Li J, Yang J, Hua L, Wang R, Li H, Zhang C, Zhang H, Li S, Zhu L, Su H
American journal of cancer research 2021;11(1):92-107
American journal of cancer research 2021;11(1):92-107
Cardiac telocytes inhibit cardiac microvascular endothelial cell apoptosis through exosomal miRNA-21-5p-targeted cdip1 silencing to improve angiogenesis following myocardial infarction.
Liao Z, Chen Y, Duan C, Zhu K, Huang R, Zhao H, Hintze M, Pu Q, Yuan Z, Lv L, Chen H, Lai B, Feng S, Qi X, Cai D
Theranostics 2021;11(1):268-291
Theranostics 2021;11(1):268-291
Autophagy-Induced HDAC6 Activity During Hypoxia Regulates Mitochondrial Energy Metabolism Through the β-Catenin/COUP-TFII Axis in Hepatocellular Carcinoma Cells.
Yan X, Qu X, Liu B, Zhao Y, Xu L, Yu S, Wang J, Wang L, Su J
Frontiers in oncology 2021;11:742460
Frontiers in oncology 2021;11:742460
Purified Vitexin Compound 1 Serves as a Promising Antineoplastic Agent in Ovarian Cancer.
Ma K, Wang K, Zhou Y, Liu N, Guo W, Qi J, Hu Z, Su S, Tang P, Zhou X
Frontiers in oncology 2021;11:734708
Frontiers in oncology 2021;11:734708
Identification of Glycolysis-Related lncRNAs and the Novel lncRNA WAC-AS1 Promotes Glycolysis and Tumor Progression in Hepatocellular Carcinoma.
Xia X, Zhang H, Xia P, Zhu Y, Liu J, Xu K, Yuan Y
Frontiers in oncology 2021;11:733595
Frontiers in oncology 2021;11:733595
Honokiol Suppresses Perineural Invasion of Pancreatic Cancer by Inhibiting SMAD2/3 Signaling.
Qin T, Li J, Xiao Y, Wang X, Gong M, Wang Q, Zhu Z, Zhang S, Zhang W, Cao F, Han L, Wang Z, Ma Q, Sha H
Frontiers in oncology 2021;11:728583
Frontiers in oncology 2021;11:728583
The Anti-Colon Cancer Effects of Essential Oil of Curcuma phaeocaulis Through Tumour Vessel Normalisation.
Feng Y, Deng L, Guo H, Zhao Y, Peng F, Wang G, Yu C
Frontiers in oncology 2021;11:728464
Frontiers in oncology 2021;11:728464
Downregulation of miR-142a Contributes to the Enhanced Anti-Apoptotic Ability of Murine Chronic Myelogenous Leukemia Cells.
Chen Z, Xie Y, Liu D, Liu P, Li F, Zhang Z, Zhang M, Wang X, Zhang Y, Sun X, Huang Q
Frontiers in oncology 2021;11:718731
Frontiers in oncology 2021;11:718731
Cystatin-B Negatively Regulates the Malignant Characteristics of Oral Squamous Cell Carcinoma Possibly Via the Epithelium Proliferation/Differentiation Program.
Xu TT, Zeng XW, Wang XH, Yang LX, Luo G, Yu T
Frontiers in oncology 2021;11:707066
Frontiers in oncology 2021;11:707066
NEK7 Promotes Pancreatic Cancer Progression And Its Expression Is Correlated With Poor Prognosis.
Yan Z, Qu J, Li Z, Yi J, Su Y, Lin Q, Yu G, Lin Z, Yin W, Lu F, Liu J
Frontiers in oncology 2021;11:705797
Frontiers in oncology 2021;11:705797
Transcriptomic Analyses of the Adenoma-Carcinoma Sequence Identify Hallmarks Associated With the Onset of Colorectal Cancer.
Hong Q, Li B, Cai X, Lv Z, Cai S, Zhong Y, Wen B
Frontiers in oncology 2021;11:704531
Frontiers in oncology 2021;11:704531
The EIF4A3/CASC2/RORA Feedback Loop Regulates the Aggressive Phenotype in Glioblastomas.
Zhao J, Jiang Y, Chen L, Ma Y, Zhang H, Zhou J, Li H, Jing Z
Frontiers in oncology 2021;11:699933
Frontiers in oncology 2021;11:699933
Aeromonas sobria Induces Proinflammatory Cytokines Production in Mouse Macrophages via Activating NLRP3 Inflammasome Signaling Pathways.
Zhang W, Li Z, Yang H, Wang G, Liu G, Wang Y, Bello BK, Zhao P, Liang W, Dong J
Frontiers in cellular and infection microbiology 2021;11:691445
Frontiers in cellular and infection microbiology 2021;11:691445
Transcriptomic Analyses Reveal B-Cell Translocation Gene 2 as a Potential Therapeutic Target in Ovarian Cancer.
Wang J, Li H, Wang L, Zhang J, Li M, Qiao L, Zhang J, Liu L, Zhang C, Gao J, Li W
Frontiers in oncology 2021;11:681250
Frontiers in oncology 2021;11:681250
The RNA-Binding Protein NELFE Promotes Gastric Cancer Growth and Metastasis Through E2F2.
Chen C, Zheng Q, Pan S, Chen W, Huang J, Cao Y, Tu Y, Li Z, Yu C, Jie Z
Frontiers in oncology 2021;11:677111
Frontiers in oncology 2021;11:677111
Long Non-Coding RNA LINC00467 Correlates to Poor Prognosis and Aggressiveness of Breast Cancer.
Zhang Y, Sun Y, Ding L, Shi W, Ding K, Zhu Y
Frontiers in oncology 2021;11:643394
Frontiers in oncology 2021;11:643394
N6-Methyladenosine Modification of LncRNA DUXAP9 Promotes Renal Cancer Cells Proliferation and Motility by Activating the PI3K/AKT Signaling Pathway.
Tan L, Tang Y, Li H, Li P, Ye Y, Cen J, Gui C, Luo J, Cao J, Wei J
Frontiers in oncology 2021;11:641833
Frontiers in oncology 2021;11:641833
Downregulation of GLYAT Facilitates Tumor Growth and Metastasis and Poor Clinical Outcomes Through the PI3K/AKT/Snail Pathway in Human Breast Cancer.
Tian X, Wu L, Jiang M, Zhang Z, Wu R, Miao J, Liu C, Gao S
Frontiers in oncology 2021;11:641399
Frontiers in oncology 2021;11:641399
MiR-454-3p Promotes Oxaliplatin Resistance by Targeting PTEN in Colorectal Cancer.
Qian XL, Zhou F, Xu S, Jiang J, Chen ZP, Wang SK, Zuo Y, Ni C
Frontiers in oncology 2021;11:638537
Frontiers in oncology 2021;11:638537
Asparagine Synthetase-Mediated l-Asparagine Metabolism Disorder Promotes the Perineural Invasion of Oral Squamous Cell Carcinoma.
Fu Y, Ding L, Yang X, Ding Z, Huang X, Zhang L, Chen S, Hu Q, Ni Y
Frontiers in oncology 2021;11:637226
Frontiers in oncology 2021;11:637226
Discovering and Characterizing of Survivin Dominant Negative Mutants With Stronger Pro-apoptotic Activity on Cancer Cells and CSCs.
Guo W, Ma X, Fu Y, Liu C, Liu Q, Hu F, Miao H, Zhang T, Liu Y, Han MH, You F, Yang Y, Zheng W
Frontiers in oncology 2021;11:635233
Frontiers in oncology 2021;11:635233
HOXA5 Is Recognized as a Prognostic-Related Biomarker and Promotes Glioma Progression Through Affecting Cell Cycle.
Ding F, Chen P, Bie P, Piao W, Cheng Q
Frontiers in oncology 2021;11:633430
Frontiers in oncology 2021;11:633430
TFEB Promotes Prostate Cancer Progression via Regulating ABCA2-Dependent Lysosomal Biogenesis.
Zhu X, Zhuo Y, Wu S, Chen Y, Ye J, Deng Y, Feng Y, Liu R, Cai S, Zou Z, Wang B, Wu CL, Zeng G, Zhong W
Frontiers in oncology 2021;11:632524
Frontiers in oncology 2021;11:632524
Identification of Hub Genes Associated With Sensitivity of 5-Fluorouracil Based Chemotherapy for Colorectal Cancer by Integrated Bioinformatics Analysis.
Wang Y, Wei Q, Chen Y, Long S, Yao Y, Fu K
Frontiers in oncology 2021;11:604315
Frontiers in oncology 2021;11:604315
IFN-γ facilitates liver fibrogenesis by CD161+CD4+ T cells through a regenerative IL-23/IL-17 axis in chronic hepatitis B virus infection.
Li J, Cheng L, Jia H, Liu C, Wang S, Liu Y, Shen Y, Wu S, Meng F, Zheng B, Yang C, Jiang W
Clinical & translational immunology 2021;10(11):e1353
Clinical & translational immunology 2021;10(11):e1353
Epigallocatechin-3-gallate inhibits proliferation and triggers apoptosis in colon cancer via the hedgehog/phosphoinositide 3-kinase pathways.
Ding F, Yang S
Canadian journal of physiology and pharmacology 2021 Sep;99(9):910-920
Canadian journal of physiology and pharmacology 2021 Sep;99(9):910-920
SARS-CoV-2 ORF9b antagonizes type I and III interferons by targeting multiple components of the RIG-I/MDA-5-MAVS, TLR3-TRIF, and cGAS-STING signaling pathways.
Han L, Zhuang MW, Deng J, Zheng Y, Zhang J, Nan ML, Zhang XJ, Gao C, Wang PH
Journal of medical virology 2021 Sep;93(9):5376-5389
Journal of medical virology 2021 Sep;93(9):5376-5389
Subicular Caspase-1 Contributes to Pharmacoresistance in Temporal Lobe Epilepsy.
Xu C, Zhang S, Gong Y, Nao J, Shen Y, Tan B, Xu S, Cui S, Ruan Y, Wang S, Wang Y, Chen Z
Annals of neurology 2021 Sep;90(3):377-390
Annals of neurology 2021 Sep;90(3):377-390
Yangonin modulates lipid homeostasis, ameliorates cholestasis and cellular senescence in alcoholic liver disease via activating nuclear receptor FXR.
Kong L, Dong R, Huang K, Wang X, Wang D, Yue N, Wang C, Sun P, Gu J, Luo H, Liu K, Wu J, Sun H, Meng Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Sep;90:153629
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Sep;90:153629
Actin-binding protein, IQGAP1, regulates LPS-induced RPMVECs hyperpermeability and ICAM-1 upregulation via Rap1/Src signalling pathway.
Zhang N, Wang G, Sun G
Cellular signalling 2021 Sep;85:110067
Cellular signalling 2021 Sep;85:110067
HOXA5 induces M2 macrophage polarization to attenuate carotid atherosclerosis by activating MED1.
Jing Y, Gao B, Han Z, Xin S
IUBMB life 2021 Sep;73(9):1142-1152
IUBMB life 2021 Sep;73(9):1142-1152
AIM2 forms a complex with pyrin and ZBP1 to drive PANoptosis and host defence.
Lee S, Karki R, Wang Y, Nguyen LN, Kalathur RC, Kanneganti TD
Nature 2021 Sep;597(7876):415-419
Nature 2021 Sep;597(7876):415-419
Disruption of Circadian Clocks Promotes Progression of Alzheimer's Disease in Diabetic Mice.
Huang J, Peng X, Fan R, Dong K, Shi X, Zhang S, Yu X, Yang Y
Molecular neurobiology 2021 Sep;58(9):4404-4412
Molecular neurobiology 2021 Sep;58(9):4404-4412
Postconditioning with Sevoflurane or Propofol Alleviates Lipopolysaccharide-Induced Neuroinflammation but Exerts Dissimilar Effects on the NR2B Subunit and Cognition.
Liu H, Chen B, Guo B, Deng X, Wang B, Dou X
Molecular neurobiology 2021 Sep;58(9):4251-4267
Molecular neurobiology 2021 Sep;58(9):4251-4267
Melatonin and doxorubicin synergistically enhance apoptosis via autophagy-dependent reduction of AMPKα1 transcription in human breast cancer cells.
Tran QH, Hoang DH, Song M, Choe W, Kang I, Kim SS, Ha J
Experimental & molecular medicine 2021 Sep;53(9):1413-1422
Experimental & molecular medicine 2021 Sep;53(9):1413-1422
Bruton's tyrosine kinase regulates macrophage‑induced inflammation in the diabetic kidney via NLRP3 inflammasome activation.
Zhao J, Chen J, Li YY, Xia LL, Wu YG
International journal of molecular medicine 2021 Sep;48(3)
International journal of molecular medicine 2021 Sep;48(3)
Environmental Microcystin exposure in underlying NAFLD-induced exacerbation of neuroinflammation, blood-brain barrier dysfunction, and neurodegeneration are NLRP3 and S100B dependent.
Mondal A, Saha P, Bose D, Chatterjee S, Seth RK, Xiao S, Porter DE, Brooks BW, Scott GI, Nagarkatti M, Nagarkatti P, Chatterjee S
Toxicology 2021 Sep;461:152901
Toxicology 2021 Sep;461:152901
Spata2 Knockdown Exacerbates Brain Inflammation via NF-κB/P38MAPK Signaling and NLRP3 Inflammasome Activation in Cerebral Ischemia/Reperfusion Rats.
Ren Y, Jiang J, Jiang W, Zhou X, Lu W, Wang J, Luo Y
Neurochemical research 2021 Sep;46(9):2262-2275
Neurochemical research 2021 Sep;46(9):2262-2275
Long noncoding RNA ANRIL knockdown attenuates neuroinflammation following ischemic stroke via suppressing the expression of NF-κB in vitro and in vivo.
Deng L, Guo Y, Liu J, Chen S, Wang X, Zhao H, Zuo T, Hu Q, Dong Z
Neurological research 2021 Sep;43(9):767-777
Neurological research 2021 Sep;43(9):767-777
KDELR2 promotes breast cancer proliferation via HDAC3-mediated cell cycle progression.
Wei H, Ma W, Lu X, Liu H, Lin K, Wang Y, Ye Z, Sun L, Huang Z, Pan T, Zhou Z, Cheng EY, Zhang H, Gao P, Zhong X
Cancer communications (London, England) 2021 Sep;41(9):904-920
Cancer communications (London, England) 2021 Sep;41(9):904-920
Gastrodin protects against high glucose-induced cardiomyocyte toxicity via GSK-3β-mediated nuclear translocation of Nrf2.
Dong Z, Bian L, Wang YL, Sun LM
Human & experimental toxicology 2021 Sep;40(9):1584-1597
Human & experimental toxicology 2021 Sep;40(9):1584-1597
An Antioxidant Sesquiterpene Inhibits Osteoclastogenesis Via Blocking IPMK/TRAF6 and Counteracts OVX-Induced Osteoporosis in Mice.
Wang S, Ma Q, Xie Z, Shen Y, Zheng B, Jiang C, Yuan P, An Q, Fan S, Jie Z
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2021 Sep;36(9):1850-1865
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2021 Sep;36(9):1850-1865
Long non-coding RNA DUXAP9 promotes hepatocellular carcinoma cell stemness via directly interacting with sox9.
Zeng R, Wang C, Wang W, Wang S
Environmental toxicology 2021 Sep;36(9):1793-1801
Environmental toxicology 2021 Sep;36(9):1793-1801
Compound essential oils relieve oxidative stress caused by PM2 .5 exposure by inhibiting autophagy through the AMPK/mTOR pathway.
Ren F, Xu X, Xu J, Mei Y, Zhang J, Wang X, Li F
Environmental toxicology 2021 Sep;36(9):1765-1774
Environmental toxicology 2021 Sep;36(9):1765-1774
CTR9-mediated JAK2/STAT3 pathway promotes the proliferation, migration, and invasion of human glioma cells.
Xu Y, Chen J, He G, Zhang Y
Journal of clinical laboratory analysis 2021 Sep;35(9):e23943
Journal of clinical laboratory analysis 2021 Sep;35(9):e23943
MiR-100-5p regulates cardiac hypertrophy through activation of autophagy by targeting mTOR.
Zeng J, Wang L, Zhao J, Zheng Z, Peng J, Zhang W, Wen T, Nie J, Ding L, Yi D
Human cell 2021 Sep;34(5):1388-1397
Human cell 2021 Sep;34(5):1388-1397
Bone marrow mesenchymal stem cell-derived exosomes induce the Th17/Treg imbalance in immune thrombocytopenia through miR-146a-5p/IRAK1 axis.
He Y, Ji D, Lu W, Li F, Huang X, Huang R, Chen G
Human cell 2021 Sep;34(5):1360-1374
Human cell 2021 Sep;34(5):1360-1374
Bovine viral diarrhea virus NS4B protein interacts with 2CARD of MDA5 domain and negatively regulates the RLR-mediated IFN-β production.
Shan Y, Tong Z, Jinzhu M, Yu L, Zecai Z, Chenhua W, Wenjing H, Siyu L, Nannan C, Siyu S, Tongtong B, Jiang H, Biaohui B, Xin J, Yulong Z, Zhanbo Z
Virus research 2021 Sep;302:198471
Virus research 2021 Sep;302:198471
Docosahexaenoic acid activates the Nrf2 signaling pathway to alleviate impairment of spleen cellular immunity in intrauterine growth restricted rat pups.
Jiang W, Wan L, Chen P, Lu W
Saudi journal of biological sciences 2021 Sep;28(9):4987-4993
Saudi journal of biological sciences 2021 Sep;28(9):4987-4993
Cinnabar protects serum-nutrient starvation induced apoptosis by improving intracellular oxidative stress and inhibiting the expression of CHOP and PERK.
Ma HH, Ding YN, Wang A, Li X, Wang Y, Shi FG, Lu YF
Biochemistry and biophysics reports 2021 Sep;27:101055
Biochemistry and biophysics reports 2021 Sep;27:101055
miR-29c-3p regulates TET2 expression and inhibits autophagy process in Parkinson's disease models.
Wang R, Yao J, Gong F, Chen S, He Y, Hu C, Li C
Genes to cells : devoted to molecular & cellular mechanisms 2021 Sep;26(9):684-697
Genes to cells : devoted to molecular & cellular mechanisms 2021 Sep;26(9):684-697
DNM3OS regulates GAPDH expression and influences the molecular pathogenesis of Huntington's disease.
Dong X, Cong S
Journal of cellular and molecular medicine 2021 Sep;25(18):9066-9071
Journal of cellular and molecular medicine 2021 Sep;25(18):9066-9071
Exogenous H2 S prevents the nuclear translocation of PDC-E1 and inhibits vascular smooth muscle cell proliferation in the diabetic state.
Zhang L, Jiang X, Liu N, Li M, Kang J, Chen L, Tang J, Dong S, Lu F, Zhang W
Journal of cellular and molecular medicine 2021 Sep;25(17):8201-8214
Journal of cellular and molecular medicine 2021 Sep;25(17):8201-8214
Salusin‑β participates in high glucose‑induced HK‑2 cell ferroptosis in a Nrf‑2‑dependent manner.
Wang WJ, Jiang X, Gao CC, Chen ZW
Molecular medicine reports 2021 Sep;24(3)
Molecular medicine reports 2021 Sep;24(3)
Lack of Mof reduces acute liver injury by enhancing transcriptional activation of Igf1.
Wang M, Liu H, Zhang X, Zhao W, Li D, Xu C, Wu Z, Xie F, Li X
Journal of cellular physiology 2021 Sep;236(9):6559-6570
Journal of cellular physiology 2021 Sep;236(9):6559-6570
PKC-β/Alox5 axis activation promotes Bcr-Abl-independent TKI-resistance in chronic myeloid leukemia.
Ma D, Liu P, Wang P, Zhou Z, Fang Q, Wang J
Journal of cellular physiology 2021 Sep;236(9):6312-6327
Journal of cellular physiology 2021 Sep;236(9):6312-6327
Propofol inhibited gastric cancer proliferation via the hsa-miR-328-3p/STAT3 pathway.
Bai ZM, Li XF, Yang Y, Yang YF, Lv DR, Tang LL
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2021 Sep;23(9):1866-1873
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2021 Sep;23(9):1866-1873
The piRNA pathway is essential for generating functional oocytes in golden hamsters.
Zhang H, Zhang F, Chen Q, Li M, Lv X, Xiao Y, Zhang Z, Hou L, Lai Y, Zhang Y, Zhang A, Gao S, Fu H, Xiao W, Zhou J, Diao F, Shi A, Su YQ, Zeng W, Wu L, Li J
Nature cell biology 2021 Sep;23(9):1013-1022
Nature cell biology 2021 Sep;23(9):1013-1022
RNA N6 -methyladenosine modification suppresses replication of rice black streaked dwarf virus and is associated with virus persistence in its insect vector.
Tian S, Wu N, Zhang L, Wang X
Molecular plant pathology 2021 Sep;22(9):1070-1081
Molecular plant pathology 2021 Sep;22(9):1070-1081
Low-dose repeated exposure to chemical surfactant impairs corneal epithelium: When personal cleaning products entering the eye.
Wu J, Wu T, Zheng S, Huang Y, Wang L
Experimental eye research 2021 Sep;210:108696
Experimental eye research 2021 Sep;210:108696
Hsa_circ_0006232 promotes laryngeal squamous cell cancer progression through FUS-mediated EZH2 stabilization.
Wu T, Wang G, Zeng X, Sun Z, Li S, Wang W, Yu B
Cell cycle (Georgetown, Tex.) 2021 Sep;20(18):1799-1811
Cell cycle (Georgetown, Tex.) 2021 Sep;20(18):1799-1811
Total Flavonoids of Engelhardia roxburghiana Wall. Leaves Alleviated Foam Cells Formation through AKT/mTOR-Mediated Autophagy in the Progression of Atherosclerosis.
Wei J, Huang L, Li D, He J, Li Y, He F, Fang W, Wei G
Chemistry & biodiversity 2021 Sep;18(9):e2100308
Chemistry & biodiversity 2021 Sep;18(9):e2100308
High mobility group box 1 mediates inflammatory response of astrocytes via cyclooxygenase 2/prostaglandin E2 signaling following spinal cord injury.
Song HH, Song TC, Yang T, Sun CS, He BQ, Li H, Wang YJ, Li Y, Wu H, Hu YM, Wang YJ
Neural regeneration research 2021 Sep;16(9):1848-1855
Neural regeneration research 2021 Sep;16(9):1848-1855
Ruyiping extract reduces lung metastasis in triple negative breast cancer by regulating macrophage polarization.
Yang R, Xie Y, Li Q, Ye Y, Shi Y, Zhao X, Wu C, Xu Y, Wang R, Zhang Y, Yang X, Han X, Liu S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Sep;141:111883
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Sep;141:111883
Quadruple-editing of the MAPK and PI3K pathways effectively blocks the progression of KRAS-mutated colorectal cancer cells.
Wang Z, Kang B, Gao Q, Huang L, Di J, Fan Y, Yu J, Jiang B, Gao F, Wang D, Sun H, Gu Y, Li J, Su X
Cancer science 2021 Sep;112(9):3895-3910
Cancer science 2021 Sep;112(9):3895-3910
METTL14 promotes glomerular endothelial cell injury and diabetic nephropathy via m6A modification of α-klotho.
Li M, Deng L, Xu G
Molecular medicine (Cambridge, Mass.) 2021 Sep 9;27(1):106
Molecular medicine (Cambridge, Mass.) 2021 Sep 9;27(1):106
Genomic and epigenomic evolution of acquired resistance to combination therapy in esophageal squamous cell carcinoma.
Min Q, Wang Y, Wu Q, Li X, Teng H, Fan J, Cao Y, Fan P, Zhan Q
JCI insight 2021 Sep 8;6(17)
JCI insight 2021 Sep 8;6(17)
Viral targeting of glioblastoma stem cells with patient-specific genetic and post-translational p53 deregulations.
Gil-Ranedo J, Gallego-García C, Almendral JM
Cell reports 2021 Sep 7;36(10):109673
Cell reports 2021 Sep 7;36(10):109673
A pair of long intergenic non-coding RNA LINC00887 variants act antagonistically to control Carbonic Anhydrase IX transcription upon hypoxia in tongue squamous carcinoma progression.
Shen T, Xia W, Min S, Yang Z, Cheng L, Wang W, Zhan Q, Shao F, Zhang X, Wang Z, Zhang Y, Shen G, Zhang H, Wu LL, Yu GY, Kong QP, Wang X
BMC biology 2021 Sep 7;19(1):192
BMC biology 2021 Sep 7;19(1):192
Cannabidiol Effectively Promoted Cell Death in Bladder Cancer and the Improved Intravesical Adhesion Drugs Delivery Strategy Could Be Better Used for Treatment.
Chen S, Deng C, Zheng W, Li S, Liu Y, Zhang T, Zhang C, Fu Y, Miao H, Ren F, Ma X
Pharmaceutics 2021 Sep 7;13(9)
Pharmaceutics 2021 Sep 7;13(9)
ACLY ubiquitination by CUL3-KLHL25 induces the reprogramming of fatty acid metabolism to facilitate iTreg differentiation.
Tian M, Hao F, Jin X, Sun X, Jiang Y, Wang Y, Li D, Chang T, Zou Y, Peng P, Xia C, Liu J, Li Y, Wang P, Feng Y, Wei M
eLife 2021 Sep 7;10
eLife 2021 Sep 7;10
LncRNA-6395 promotes myocardial ischemia-reperfusion injury in mice through increasing p53 pathway.
Zhan LF, Zhang Q, Zhao L, Dong X, Pei XY, Peng LL, Zhang XW, Meng B, Shang WD, Pan ZW, Xu CQ, Lu YJ, Zhang MY
Acta pharmacologica Sinica 2021 Sep 7;
Acta pharmacologica Sinica 2021 Sep 7;
Sema3A accelerates bone formation during distraction osteogenesis in mice.
Zhang N, Hua Y, Li Y, Pan J
Connective tissue research 2021 Sep 5;:1-11
Connective tissue research 2021 Sep 5;:1-11
Stimulation of ROS Generation by Extract of Warburgia ugandensis Leading to G0/G1 Cell Cycle Arrest and Antiproliferation in A549 Cells.
Zhang YL, Chen GL, Liu Y, Zhuang XC, Guo MQ
Antioxidants (Basel, Switzerland) 2021 Sep 30;10(10)
Antioxidants (Basel, Switzerland) 2021 Sep 30;10(10)
Identification and Characterization of Eimeria tenella Microneme Protein (EtMIC8).
Zhao N, Ming S, Sun L, Wang B, Li H, Zhang X, Zhao X
Microbiology spectrum 2021 Sep 3;9(1):e0022821
Microbiology spectrum 2021 Sep 3;9(1):e0022821
HIF-1α/JMJD1A signaling regulates inflammation and oxidative stress following hyperglycemia and hypoxia-induced vascular cell injury.
Zhao M, Wang S, Zuo A, Zhang J, Wen W, Jiang W, Chen H, Liang D, Sun J, Wang M
Cellular & molecular biology letters 2021 Sep 3;26(1):40
Cellular & molecular biology letters 2021 Sep 3;26(1):40
Adipose expression of CREB3L3 modulates body weight during obesity.
McCann MA, Li Y, Muñoz M, Gil V, Qiang G, Cordoba-Chacon J, Blüher M, Duncan S, Liew CW
Scientific reports 2021 Sep 29;11(1):19400
Scientific reports 2021 Sep 29;11(1):19400
Hexokinase 2-mediated glycolysis promotes receptor activator of NF-κB ligand expression in Porphyromonas gingivalis lipopolysaccharide-treated osteoblasts.
Yu Y, Jiang L, Li J, Lei L, Li H
Journal of periodontology 2021 Sep 29;
Journal of periodontology 2021 Sep 29;
Exosomal microRNA-588 from M2 polarized macrophages contributes to cisplatin resistance of gastric cancer cells.
Cui HY, Rong JS, Chen J, Guo J, Zhu JQ, Ruan M, Zuo RR, Zhang SS, Qi JM, Zhang BH
World journal of gastroenterology 2021 Sep 28;27(36):6079-6092
World journal of gastroenterology 2021 Sep 28;27(36):6079-6092
Dual Inhibition of Endoplasmic Reticulum Stress and Oxidation Stress Manipulates the Polarization of Macrophages under Hypoxia to Sensitize Immunotherapy.
Jiang M, Li X, Zhang J, Lu Y, Shi Y, Zhu C, Liu Y, Qin B, Luo Z, Du Y, Luo L, Peng L, You J
ACS nano 2021 Sep 28;15(9):14522-14534
ACS nano 2021 Sep 28;15(9):14522-14534
Identification of genes and pathways leading to metastasis and poor prognosis in melanoma.
Zhang X, Wang W, Wang Y, Jiang G
Aging 2021 Sep 28;13(18):22474-22489
Aging 2021 Sep 28;13(18):22474-22489
Regulatory variants at 2q33.1 confer schizophrenia risk by modulating distal gene TYW5 expression.
Li S, Li J, Liu J, Wang J, Li X, Huo Y, Li Y, Liu Y, Li M, Xiao X, Luo XJ
Brain : a journal of neurology 2021 Sep 28;
Brain : a journal of neurology 2021 Sep 28;
The Ginsenoside Rg1 Rescues Mitochondrial Disorders in Aristolochic Acid-Induced Nephropathic Mice.
Chou CK, Huang YS, Lin PY, Imai K, Chen SM, Lee JA
Life (Basel, Switzerland) 2021 Sep 27;11(10)
Life (Basel, Switzerland) 2021 Sep 27;11(10)
Anti-osteosarcoma effect of antiserum against cross antigen TPD52 between osteosarcoma and Trichinella spiralis.
Yue TT, Zhang N, Li JH, Lu XY, Wang XC, Li X, Zhang HB, Cheng SQ, Wang BB, Gong PT, Zhang XC
Parasites & vectors 2021 Sep 26;14(1):498
Parasites & vectors 2021 Sep 26;14(1):498
MEST promotes lung cancer invasion and metastasis by interacting with VCP to activate NF-κB signaling.
Wang Y, Zhang J, Li YJ, Yu NN, Liu WT, Liang JZ, Xu WW, Sun ZH, Li B, He QY
Journal of experimental & clinical cancer research : CR 2021 Sep 24;40(1):301
Journal of experimental & clinical cancer research : CR 2021 Sep 24;40(1):301
Differential expression of long non-coding RNAs in the hippocampus of mice exposed to PM2.5 in Dalian, China.
Li J, Zhang L, Wang J, Jia R, Zhang X, Li X, Fu Y, Song L
Environmental science and pollution research international 2021 Sep 24;
Environmental science and pollution research international 2021 Sep 24;
Potent Inhibition of HIF1α and p300 Interaction by a Constrained Peptide Derived from CITED2.
Qin X, Chen H, Tu L, Ma Y, Liu N, Zhang H, Li D, Riedl B, Bierer D, Yin F, Li Z
Journal of medicinal chemistry 2021 Sep 23;64(18):13693-13703
Journal of medicinal chemistry 2021 Sep 23;64(18):13693-13703
Discovery of a Potent Glutathione Peroxidase 4 Inhibitor as a Selective Ferroptosis Inducer.
Xu C, Xiao Z, Wang J, Lai H, Zhang T, Guan Z, Xia M, Chen M, Ren L, He Y, Gao Y, Zhao C
Journal of medicinal chemistry 2021 Sep 23;64(18):13312-13326
Journal of medicinal chemistry 2021 Sep 23;64(18):13312-13326
Transgelin-2 interacts with CD44 to regulate Notch1 signaling pathway and participates in colorectal cancer proliferation and migration.
Ding R, Li G, Yao Y, Zhang L, Zhang X, Li J, Shen T, Gao Y, Wu T, Kong S, Huang M, Li Y
Journal of physiology and biochemistry 2021 Sep 23;
Journal of physiology and biochemistry 2021 Sep 23;
Perinatal low-dose bisphenol AF exposure impairs synaptic plasticity and cognitive function of adult offspring in a sex-dependent manner.
Zhang C, Wu XC, Li S, Dou LJ, Zhou L, Wang FH, Ma K, Huang D, Pan Y, Gu JJ, Cao JY, Wang H, Hao JH
The Science of the total environment 2021 Sep 20;788:147918
The Science of the total environment 2021 Sep 20;788:147918
Genistein exhibits therapeutic potential for PCOS mice via the ER-Nrf2-Foxo1-ROS pathway.
Luo M, Zheng LW, Wang YS, Huang JC, Yang ZQ, Yue ZP, Guo B
Food & function 2021 Sep 20;12(18):8800-8811
Food & function 2021 Sep 20;12(18):8800-8811
Isonicotinylation is a histone mark induced by the anti-tuberculosis first-line drug isoniazid.
Jiang Y, Li Y, Liu C, Zhang L, Lv D, Weng Y, Cheng Z, Chen X, Zhan J, Zhang H
Nature communications 2021 Sep 20;12(1):5548
Nature communications 2021 Sep 20;12(1):5548
β-adrenergic receptor inhibition enhances oncolytic herpes virus propagation through STAT3 activation in gastric cancer.
Hu J, Lu R, Zhang Y, Li W, Hu Q, Chen C, Liu Z, Zhang W, Chen L, Xu R, Luo J, McLeod HL, He Y
Cell & bioscience 2021 Sep 20;11(1):174
Cell & bioscience 2021 Sep 20;11(1):174
Ultramicronized Palmitoylethanolamide Inhibits NLRP3 Inflammasome Expression and Pro-Inflammatory Response Activated by SARS-CoV-2 Spike Protein in Cultured Murine Alveolar Macrophages.
Del Re A, Corpetti C, Pesce M, Seguella L, Steardo L, Palenca I, Rurgo S, De Conno B, Sarnelli G, Esposito G
Metabolites 2021 Sep 2;11(9)
Metabolites 2021 Sep 2;11(9)
RIOK2 Inhibitor NSC139021 Exerts Anti-Tumor Effects on Glioblastoma via Inducing Skp2-Mediated Cell Cycle Arrest and Apoptosis.
Yu M, Hu X, Yan J, Wang Y, Lu F, Chang J
Biomedicines 2021 Sep 17;9(9)
Biomedicines 2021 Sep 17;9(9)
Lactobacillus johnsonii L531 Alleviates the Damage Caused by Salmonella Typhimurium via Inhibiting TLR4, NF-κB, and NLRP3 Inflammasome Signaling Pathways.
Chen S, Li Y, Chu B, Yuan L, Liu N, Zhu Y, Wang J
Microorganisms 2021 Sep 17;9(9)
Microorganisms 2021 Sep 17;9(9)
KIF15 upregulation promotes leiomyosarcoma cell growth via promoting USP15-mediated DEK deubiquitylation.
Ge W, Chen Y, Guo Y, Zhao D, Mu L, Zhang K, Zhuo W
Biochemical and biophysical research communications 2021 Sep 17;570:117-124
Biochemical and biophysical research communications 2021 Sep 17;570:117-124
UBE2S promotes the progression and Olaparib resistance of ovarian cancer through Wnt/β-catenin signaling pathway.
Hu W, Li M, Chen Y, Gu X
Journal of ovarian research 2021 Sep 17;14(1):121
Journal of ovarian research 2021 Sep 17;14(1):121
HSF1 is involved in suppressing A1 phenotype conversion of astrocytes following spinal cord injury in rats.
Li L, Li Y, He B, Li H, Ji H, Wang Y, Zhu Z, Hu Y, Zhou Y, Yang T, Sun C, Yuan Y, Wang Y
Journal of neuroinflammation 2021 Sep 16;18(1):205
Journal of neuroinflammation 2021 Sep 16;18(1):205
MiR-200c-3p promotes ox-LDL-induced endothelial to mesenchymal transition in human umbilical vein endothelial cells through SMAD7/YAP pathway.
Mao Y, Jiang L
The journal of physiological sciences : JPS 2021 Sep 15;71(1):30
The journal of physiological sciences : JPS 2021 Sep 15;71(1):30
Harmine-inspired design and synthesis of benzo[d]imidazo[2,1-b]thiazole derivatives bearing 1,3,4-oxadiazole moiety as potential tumor suppressors.
Zhao T, Yang Y, Yang J, Cui Y, Cao Z, Zuo D, Zhai X
Bioorganic & medicinal chemistry 2021 Sep 15;46:116367
Bioorganic & medicinal chemistry 2021 Sep 15;46:116367
Hypoxia increases KIAA1199/CEMIP expression and enhances cell migration in pancreatic cancer.
Oba T, Sato N, Adachi Y, Amaike T, Kudo Y, Koga A, Kohi S, Hirata K
Scientific reports 2021 Sep 14;11(1):18193
Scientific reports 2021 Sep 14;11(1):18193
Exogenous melatonin prevents type 1 diabetes mellitus-induced bone loss, probably by inhibiting senescence.
Gong Z, Da W, Tian Y, Zhao R, Qiu S, Wu Q, Wen K, Shen L, Zhou R, Tao L, Zhu Y
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2021 Sep 14;
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2021 Sep 14;
Genetically variant human pluripotent stem cells selectively eliminate wild-type counterparts through YAP-mediated cell competition.
Price CJ, Stavish D, Gokhale PJ, Stevenson BA, Sargeant S, Lacey J, Rodriguez TA, Barbaric I
Developmental cell 2021 Sep 13;56(17):2455-2470.e10
Developmental cell 2021 Sep 13;56(17):2455-2470.e10
Ketamine ameliorates depressive-like behaviors in mice through increasing glucose uptake regulated by the ERK/GLUT3 signaling pathway.
Ouyang X, Wang Z, Luo M, Wang M, Liu X, Chen J, Feng J, Jia J, Wang X
Scientific reports 2021 Sep 13;11(1):18181
Scientific reports 2021 Sep 13;11(1):18181
A standardized extract of Asparagus officinalis stem improves HSP70-mediated redox balance and cell functions in bovine cumulus-granulosa cells.
Ho KT, Homma K, Takanari J, Bai H, Kawahara M, Nguyen KTK, Takahashi M
Scientific reports 2021 Sep 13;11(1):18175
Scientific reports 2021 Sep 13;11(1):18175
2,5-dimethyl celecoxib induces apoptosis and autophagy via activation of ROS/JNK axis in nasopharyngeal carcinoma cells.
Tan T, Fu X, Qu J, Zhang M, Chen H, Wang Y, Wang B, Li J, Liu J, Liu P
Aging 2021 Sep 12;13(17):21483-21496
Aging 2021 Sep 12;13(17):21483-21496
Defining the Cholesterol Lowering Mechanism of Bergamot (Citrus bergamia) Extract in HepG2 and Caco-2 Cells.
Huang Y, Tocmo R, Nauman MC, Haughan MA, Johnson JJ
Nutrients 2021 Sep 10;13(9)
Nutrients 2021 Sep 10;13(9)
Targeting chromosome trisomy for chromosome editing.
Abe T, Suzuki Y, Ikeya T, Hirota K
Scientific reports 2021 Sep 10;11(1):18054
Scientific reports 2021 Sep 10;11(1):18054
Baicalein Enhances the Effect of Acarbose on the Improvement of Nonalcoholic Fatty Liver Disease Associated with Prediabetes via the Inhibition of De Novo Lipogenesis.
Xing Y, Ren X, Li X, Sui L, Shi X, Sun Y, Quan C, Xiu Z, Dong Y
Journal of agricultural and food chemistry 2021 Sep 1;69(34):9822-9836
Journal of agricultural and food chemistry 2021 Sep 1;69(34):9822-9836
H2S alleviates aortic aneurysm and dissection: Crosstalk between transforming growth factor 1 signaling and NLRP3 inflammasome.
Cui J, Xu G, Bian F
International journal of cardiology 2021 Sep 1;338:215-225
International journal of cardiology 2021 Sep 1;338:215-225
Silica nanoparticles inhibiting the differentiation of round spermatid and chromatin remodeling of haploid period via MIWI in mice.
Liu J, Li X, Zhou G, Zhang Y, Sang Y, Wang J, Li Y, Ge W, Sun Z, Zhou X
Environmental pollution (Barking, Essex : 1987) 2021 Sep 1;284:117446
Environmental pollution (Barking, Essex : 1987) 2021 Sep 1;284:117446
LncAY controls BMI1 expression and activates BMI1/Wnt/β-catenin signaling axis in hepatocellular carcinoma.
Chen MH, Fu LS, Zhang F, Yang Y, Wu XZ
Life sciences 2021 Sep 1;280:119748
Life sciences 2021 Sep 1;280:119748
Sitagliptin attenuates endothelial dysfunction independent of its blood glucose controlling effect.
Chang XM, Xiao F, Pan Q, Wang XX, Guo LX
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2021 Sep 1;25(5):425-437
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2021 Sep 1;25(5):425-437
LncRNA OIP5-AS1 inhibits ferroptosis in prostate cancer with long-term cadmium exposure through miR-128-3p/SLC7A11 signaling.
Zhang Y, Guo S, Wang S, Li X, Hou D, Li H, Wang L, Xu Y, Ma B, Wang H, Jiang X
Ecotoxicology and environmental safety 2021 Sep 1;220:112376
Ecotoxicology and environmental safety 2021 Sep 1;220:112376
Yeast Shells Encapsulating Adjuvant AS04 as an Antigen Delivery System for a Novel Vaccine against Toxoplasma Gondii.
Zhu L, Lei Z, Xia X, Zhang Y, Chen Y, Wang B, Li J, Li G, Yang G, Cao G, Yin Z
ACS applied materials & interfaces 2021 Sep 1;13(34):40415-40428
ACS applied materials & interfaces 2021 Sep 1;13(34):40415-40428
Radiation-Induced Autophagy in Human Pancreatic Cancer Cells is Critically Dependent on G2 Checkpoint Activation: A Mechanism of Radioresistance in Pancreatic Cancer.
Suzuki M, Anko M, Ohara M, Matsumoto KI, Hasegawa S
International journal of radiation oncology, biology, physics 2021 Sep 1;111(1):260-271
International journal of radiation oncology, biology, physics 2021 Sep 1;111(1):260-271
Sodium butyrate alleviates pre-eclampsia in pregnant rats by improving the gut microbiota and short-chain fatty acid metabolites production.
Yong W, Zhao Y, Jiang X, Li P
Journal of applied microbiology 2021 Sep 1;
Journal of applied microbiology 2021 Sep 1;
Ornithine decarboxylase of the fungal pathogen Colletotrichum higginsianum plays an important role in regulating global metabolic pathways and virulence.
Yan Y, Tang J, Yuan Q, Liu H, Huang J, Hsiang T, Bao C, Zheng L
Environmental microbiology 2021 Sep 1;
Environmental microbiology 2021 Sep 1;
JNK inhibition alleviates delayed neurocognitive recovery after surgery by limiting microglia pyroptosis.
He J, Liu T, Li Y, Mi X, Han D, Yang N, Chen L, Li Y, Hong J, Kuang C, Yuan Y, Cao Y, Han Y, Shi C, Li Z, Guo X
International immunopharmacology 2021 Oct;99:107962
International immunopharmacology 2021 Oct;99:107962
Thymus quinquecostatus Celak. ameliorates cerebral ischemia-reperfusion injury via dual antioxidant actions: Activating Keap1/Nrf2/HO-1 signaling pathway and directly scavenging ROS.
Fan S, Liu X, Wang Y, Ren X, Liu Y, Dong Y, Fan Q, Wei J, Ma J, Yu A, Song R, Sui H, Shen M, Fang F, Xia Q, She G
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Oct;91:153673
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Oct;91:153673
Lactobacillus casei relieves liver injury by regulating immunity and suppression of the enterogenic endotoxin-induced inflammatory response in rats cotreated with alcohol and iron.
Li X, Han J, Liu Y, Liang H
Food science & nutrition 2021 Oct;9(10):5391-5401
Food science & nutrition 2021 Oct;9(10):5391-5401
Characteristics and clinical significance of polyploid giant cancer cells in laryngeal carcinoma.
Liu HT, Xia T, You YW, Zhang QC, Ni HS, Liu YF, Liu YR, Xu YQ, You B, Zhang ZX
Laryngoscope investigative otolaryngology 2021 Oct;6(5):1228-1234
Laryngoscope investigative otolaryngology 2021 Oct;6(5):1228-1234
SETD3 Downregulation Mediates PTEN Upregulation-Induced Ischemic Neuronal Death Through Suppression of Actin Polymerization and Mitochondrial Function.
Xu X, Cui Y, Li C, Wang Y, Cheng J, Chen S, Sun J, Ren J, Yao X, Gao J, Huang X, Wan Q, Wang Q
Molecular neurobiology 2021 Oct;58(10):4906-4920
Molecular neurobiology 2021 Oct;58(10):4906-4920
Systematic screening identifies a TEAD4-S100A13 axis modulating cisplatin sensitivity of oral squamous cell carcinoma cells.
Li R, Li W, He F, Zhang M, Luo H, Tang H
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2021 Oct;50(9):882-890
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2021 Oct;50(9):882-890
Alpha-ketoglutarate ameliorates pressure overload-induced chronic cardiac dysfunction in mice.
An D, Zeng Q, Zhang P, Ma Z, Zhang H, Liu Z, Li J, Ren H, Xu D
Redox biology 2021 Oct;46:102088
Redox biology 2021 Oct;46:102088
CTHRC1 Knockdown Promotes Inflammatory Responses Partially by p38 MAPK Activation in Human Periodontal Ligament Cells.
Guo Y, Jiang C, Yao S, Ma L, Zhang H, Wang X, Xu S, Cao Z
Inflammation 2021 Oct;44(5):1831-1842
Inflammation 2021 Oct;44(5):1831-1842
Interleukin-38 Suppresses Cell Migration and Proliferation and Promotes Apoptosis of Colorectal Cancer Cell Through Negatively Regulating Extracellular Signal-Regulated Kinases Signaling.
Huang L, Zhang H, Zhao D, Hu H, Lu Z
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2021 Oct;41(10):375-384
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2021 Oct;41(10):375-384
High-mobility group AT-Hook 1 mediates the role of nuclear factor I/X in osteogenic differentiation through activating canonical Wnt signaling.
Wu X, Wang X, Shan L, Zhou J, Zhang X, Zhu E, Yuan H, Wang B
Stem cells (Dayton, Ohio) 2021 Oct;39(10):1349-1361
Stem cells (Dayton, Ohio) 2021 Oct;39(10):1349-1361
Autographa Californica Multiple Nucleopolyhedrovirus orf13 Is Required for Efficient Nuclear Egress of Nucleocapsids.
Chen X, Yang X, Lei C, Qin F, Sun X, Hu J
Virologica Sinica 2021 Oct;36(5):968-980
Virologica Sinica 2021 Oct;36(5):968-980
An enzyme-responsive Gp1a-hydrogel for skin wound healing.
Zhao C, Dong Y, Liu J, Cai H, Li Z, Sun X, Yin W, Ma J, Liu H, Li S
Journal of biomaterials applications 2021 Oct;36(4):714-721
Journal of biomaterials applications 2021 Oct;36(4):714-721
Imbalanced inflammatory response in subchronic arsenic-induced liver injury and the protective effects of Ginkgo biloba extract in rats: Potential role of cytokines mediated cell-cell interactions.
Dong L, Liu Y, Wang D, Zhu K, Zou Z, Zhang A
Environmental toxicology 2021 Oct;36(10):2073-2092
Environmental toxicology 2021 Oct;36(10):2073-2092
5-IP7 is a GPCR messenger mediating neural control of synaptotagmin-dependent insulin exocytosis and glucose homeostasis.
Zhang X, Li N, Zhang J, Zhang Y, Yang X, Luo Y, Zhang B, Xu Z, Zhu Z, Yang X, Yan Y, Lin B, Wang S, Chen D, Ye C, Ding Y, Lou M, Wu Q, Hou Z, Zhang K, Liang Z, Wei A, Wang B, Wang C, Jiang N, Zhang W, Xiao G, Ma C, Ren Y, Qi X, Han W, Wang C, Rao F
Nature metabolism 2021 Oct;3(10):1400-1414
Nature metabolism 2021 Oct;3(10):1400-1414
Dynamin-related protein 1 regulates substrate oxidation in skeletal muscle by stabilizing cellular and mitochondrial calcium dynamics.
King WT, Axelrod CL, Zunica ERM, Noland RC, Davuluri G, Fujioka H, Tandler B, Pergola K, Hermann GE, Rogers RC, López-Domènech S, Dantas WS, Stadler K, Hoppel CL, Kirwan JP
The Journal of biological chemistry 2021 Oct;297(4):101196
The Journal of biological chemistry 2021 Oct;297(4):101196
Arsenic Trioxide Combining Leflunomide Activates Nrf2-ARE-HO-1 Signaling Pathway and Protects Heart Xenografts.
Wang TD, Xu SL, Yu ZY, Ni SB, Zhang C, Jiao ZX
Chinese journal of integrative medicine 2021 Oct;27(10):760-766
Chinese journal of integrative medicine 2021 Oct;27(10):760-766
MicroRNA ssc-miR-124a exhibits antiviral activity against porcine reproductive and respiratory syndrome virus via suppression of host genes CD163.
Li N, Huang K, Chen Y, Huang Z, Zhang Y, Leng C, Liu Y, Shi J, Xiao S, Yao L
Veterinary microbiology 2021 Oct;261:109216
Veterinary microbiology 2021 Oct;261:109216
TRIM21 negatively regulates Corynebacterium pseudotuberculosis-induced inflammation and is critical for the survival of C. pseudotuberculosis infected C57BL6 mice.
Tan J, Yi W, Wang Z, Ye C, Tian S, Li X, Zou A, Zhao X, Yuan Y, Wang X, Hu S, Zhou Z
Veterinary microbiology 2021 Oct;261:109209
Veterinary microbiology 2021 Oct;261:109209
Reactive oxygen species induced by uric acid promote NRK‑52E cell apoptosis through the NEK7‑NLRP3 signaling pathway.
Li D, Wang L, Ou J, Wang C, Zhou J, Lu L, Wu Y, Gao J
Molecular medicine reports 2021 Oct;24(4)
Molecular medicine reports 2021 Oct;24(4)
Hsa_circ_0004058 inhibits apoptosis of SRA01/04 cells by promoting autophagy via miR-186/ATG7 axis.
Wang Y, Wu Z, Huang Y, Zhang Y
Experimental eye research 2021 Oct;211:108721
Experimental eye research 2021 Oct;211:108721
Advanced Maternal Age-associated SIRT1 Deficiency Compromises Trophoblast Epithelial-Mesenchymal Transition through an Increase in Vimentin Acetylation.
Xiong L, Ye X, Chen Z, Fu H, Li S, Xu P, Yu J, Wen L, Gao R, Fu Y, Qi H, Kilby MD, Saffery R, Baker PN, Tong C
Aging cell 2021 Oct;20(10):e13491
Aging cell 2021 Oct;20(10):e13491
Activation of angiotensin-converting enzyme 2/angiotensin (1-7)/mas receptor axis triggers autophagy and suppresses microglia proinflammatory polarization via forkhead box class O1 signaling.
Dang R, Yang M, Cui C, Wang C, Zhang W, Geng C, Han W, Jiang P
Aging cell 2021 Oct;20(10):e13480
Aging cell 2021 Oct;20(10):e13480
Peptides derived from viral glycoprotein Gc Inhibit infection of severe fever with thrombocytopenia syndrome virus.
Gao C, Yu Y, Wen C, Li Z, Sun M, Gao S, Lin S, Wang S, Zou P, Xing Z
Antiviral research 2021 Oct;194:105164
Antiviral research 2021 Oct;194:105164
RSL3 enhances the antitumor effect of cisplatin on prostate cancer cells via causing glycolysis dysfunction.
Li M, Chen X, Wang X, Wei X, Wang D, Liu X, Xu L, Batu W, Li Y, Guo B, Zhang L
Biochemical pharmacology 2021 Oct;192:114741
Biochemical pharmacology 2021 Oct;192:114741
PIKE-A promotes glioblastoma growth by driving PPP flux through increasing G6PD expression mediated by phosphorylation of STAT3.
Sun M, Sheng H, Wu T, Song J, Sun H, Wang Y, Wang J, Li Z, Zhao H, Tan J, Li Y, Chen G, Huang Q, Zhang Y, Lan B, Liu S, Shan C, Zhang S
Biochemical pharmacology 2021 Oct;192:114736
Biochemical pharmacology 2021 Oct;192:114736
Dihydroartemisinin regulates lipid droplet metabolism in hepatic stellate cells by inhibiting lncRNA-H19-induced AMPK signal.
Xia S, Wang Z, Chen L, Zhou Y, Li Y, Wang S, Chen A, Xu X, Shao J, Zhang Z, Tan S, Zhang F, Zheng S
Biochemical pharmacology 2021 Oct;192:114730
Biochemical pharmacology 2021 Oct;192:114730
LncRNA-Malat1 down-regulates miR-211-5p expression to promote neuronal damage from cerebral ischemia reperfusion injury.
Tan X, Guo W, Peng Z, Gu C, Xiang P, Tu Y, Fei H, Liu X, Lu Y, Li M, Wang H, Luo Y, Yang J
Biochemical pharmacology 2021 Oct;192:114694
Biochemical pharmacology 2021 Oct;192:114694
Ginsenoside Rg1 prevents bone marrow mesenchymal stem cell senescence via NRF2 and PI3K/Akt signaling.
Wang Z, Wang L, Jiang R, Li C, Chen X, Xiao H, Hou J, Hu L, Huang C, Wang Y
Free radical biology & medicine 2021 Oct;174:182-194
Free radical biology & medicine 2021 Oct;174:182-194
A purified human platelet pellet lysate rich in neurotrophic factors and antioxidants repairs and protects corneal endothelial cells from oxidative stress.
Widyaningrum R, Burnouf T, Nebie O, Delila L, Wang TJ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Oct;142:112046
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Oct;142:112046
Deletion of ribosomal paralogs Rpl39 and Rpl39l compromises cell proliferation via protein synthesis and mitochondrial activity.
Zou Q, Qi H
The international journal of biochemistry & cell biology 2021 Oct;139:106070
The international journal of biochemistry & cell biology 2021 Oct;139:106070
Design, synthesis and antitumor evaluation of novel chiral diaryl substituted azetidin-2-one derivatives as tubulin polymerization inhibitors.
Liang Y, Zhang M, Zhou P, Liu M, Li J, Wang Y
Bioorganic chemistry 2021 Oct;115:105239
Bioorganic chemistry 2021 Oct;115:105239
Transcription factor POU4F2 promotes colorectal cancer cell migration and invasion through hedgehog-mediated epithelial-mesenchymal transition.
Guo K, Wang P, Zhang L, Zhou Y, Dai X, Yan Y, Chen Y, Wasan HS, Yu J, Ruan S, Sun L
Cancer science 2021 Oct;112(10):4176-4186
Cancer science 2021 Oct;112(10):4176-4186
Aberrant expression of SNHG12 contributes to N, N-dimethylformamide-induced hepatic apoptosis both in short-term and long-term DMF exposure.
Liu Y, Wen C, Zhang Y, Liu Z, He Q, Cui M, Peng H, Wang Y, Zhang X, Li X, Wang Q
Toxicology research 2021 Oct;10(5):1022-1033
Toxicology research 2021 Oct;10(5):1022-1033
Protocols for Characterization of Cdk5 Kinase Activity.
Terse A, Amin N, Hall B, Bhaskar M, B K B, Utreras E, Pareek TK, Pant H, Kulkarni AB
Current protocols 2021 Oct;1(10):e276
Current protocols 2021 Oct;1(10):e276
CENPA promotes clear cell renal cell carcinoma progression and metastasis via Wnt/β-catenin signaling pathway.
Wang Q, Xu J, Xiong Z, Xu T, Liu J, Liu Y, Chen J, Shi J, Shou Y, Yue C, Liu D, Liang H, Yang H, Yang X, Zhang X
Journal of translational medicine 2021 Oct 9;19(1):417
Journal of translational medicine 2021 Oct 9;19(1):417
sTNFRII-Fc modification protects human UC-MSCs against apoptosis/autophagy induced by TNF-α and enhances their efficacy in alleviating inflammatory arthritis.
Zhao Y, Yang X, Li S, Zhang B, Li S, Wang X, Wang Y, Jia C, Chang Y, Wei W
Stem cell research & therapy 2021 Oct 9;12(1):535
Stem cell research & therapy 2021 Oct 9;12(1):535
Glycogen synthase kinase 3 drives thymocyte egress by suppressing β-catenin activation of Akt.
Liu C, Ma L, Wang Y, Zhao J, Chen P, Chen X, Wang Y, Hu Y, Liu Y, Jia X, Yang Z, Yin X, Wu J, Wu S, Zheng H, Ma X, Sun X, He Y, Lin L, Fu Y, Liao K, Zhou X, Jiang S, Fu G, Tang J, Han W, Chen XL, Fan W, Hong Y, Han J, Huang X, Li BA, Xiao N, Xiao C, Fu G, Liu WH
Science advances 2021 Oct 8;7(41):eabg6262
Science advances 2021 Oct 8;7(41):eabg6262
d-mannose attenuates lipopolysaccharide-induced osteolysis via CPT1A-Mediated lipid metabolic regulation in macrophages.
Zhang Z, Zhou X, Liu J, Zheng Y, Wu Y, Yang W, Yi Y, Liu J, Wang J
Biochemical and biophysical research communications 2021 Oct 8;583:135-141
Biochemical and biophysical research communications 2021 Oct 8;583:135-141
TDAG51 induces renal interstitial fibrosis through modulation of TGF-β receptor 1 in chronic kidney disease.
Carlisle RE, Mohammed-Ali Z, Lu C, Yousof T, Tat V, Nademi S, MacDonald ME, Austin RC, Dickhout JG
Cell death & disease 2021 Oct 8;12(10):921
Cell death & disease 2021 Oct 8;12(10):921
Sulforaphane downregulated fatty acid synthase and inhibited microtubule-mediated mitophagy leading to apoptosis.
Yan Y, Zhou Y, Li J, Zheng Z, Hu Y, Li L, Wu W
Cell death & disease 2021 Oct 7;12(10):917
Cell death & disease 2021 Oct 7;12(10):917
Tetrahedral Framework Nucleic Acid Delivered RNA Therapeutics Significantly Attenuate Pancreatic Cancer Progression via Inhibition of CTR1-Dependent Copper Absorption.
Song G, Dong H, Ma D, Wang H, Ren X, Qu Y, Wu H, Zhu J, Song W, Meng Y, Wang L, Liu T, Shen X, Zhao Y, Zhu C
ACS applied materials & interfaces 2021 Oct 6;13(39):46334-46342
ACS applied materials & interfaces 2021 Oct 6;13(39):46334-46342
PDCD4 Simultaneously Promotes Microglia Activation via PDCD4-MAPK-NF-κB Positive Loop and Facilitates Neuron Apoptosis During Neuroinflammation.
Chen Q, Lu H, Duan C, Zhu X, Zhang Y, Li M, Zhang D
Inflammation 2021 Oct 6;
Inflammation 2021 Oct 6;
Leojaponin inhibits NLRP3 inflammasome activation through restoration of autophagy via upregulating RAPTOR phosphorylation.
Zhang XJ, Shang K, Pu YK, Wang Q, Wang TT, Zou Y, Wang YM, Xu YJ, Li XL, Zhang RH, Xiao WL
Journal of ethnopharmacology 2021 Oct 5;278:114322
Journal of ethnopharmacology 2021 Oct 5;278:114322
p53 transcriptionally regulates SQLE to repress cholesterol synthesis and tumor growth.
Sun H, Li L, Li W, Yang F, Zhang Z, Liu Z, Du W
EMBO reports 2021 Oct 5;22(10):e52537
EMBO reports 2021 Oct 5;22(10):e52537
PFP@PLGA/Cu12Sb4S13-mediated PTT ablates hepatocellular carcinoma by inhibiting the RAS/MAPK/MT-CO1 signaling pathway.
Dong T, Jiang J, Zhang H, Liu H, Zou X, Niu J, Mao Y, Zhu M, Chen X, Li Z, Chen Y, Shi C, Yang X
Nano convergence 2021 Oct 4;8(1):29
Nano convergence 2021 Oct 4;8(1):29
Newcastle disease virus degrades SIRT3 via PINK1-PRKN-dependent mitophagy to reprogram energy metabolism in infected cells.
Gong Y, Tang N, Liu P, Sun Y, Lu S, Liu W, Tan L, Song C, Qiu X, Liao Y, Yu S, Liu X, Lin SH, Ding C
Autophagy 2021 Oct 31;:1-19
Autophagy 2021 Oct 31;:1-19
FAIM regulates autophagy through glutaminolysis in lung adenocarcinoma.
Han T, Wang P, Wang Y, Xun W, Lei J, Wang T, Lu Z, Gan M, Zhang W, Yu B, Wang JB
Autophagy 2021 Oct 31;:1-17
Autophagy 2021 Oct 31;:1-17
Activation of G protein coupled estrogen receptor prevents chemotherapy-induced intestinal mucositis by inhibiting the DNA damage in crypt cell in an extracellular signal-regulated kinase 1- and 2- dependent manner.
Chen G, Zeng H, Li X, Liu J, Li Z, Xu R, Ma Y, Liu C, Xue B
Cell death & disease 2021 Oct 30;12(11):1034
Cell death & disease 2021 Oct 30;12(11):1034
ATP-binding cassette protein ABCF1 couples transcription and genome surveillance in embryonic stem cells through low-complexity domain.
Choi EB, Vodnala M, Zerbato M, Wang J, Ho JJ, Inouye C, Ding L, Fong YW
Science advances 2021 Oct 29;7(44):eabk2775
Science advances 2021 Oct 29;7(44):eabk2775
Stigmasterol inhibits the progression of lung cancer by regulating retinoic acid-related orphan receptor C.
Dong Y, Chen C, Chen C, Zhang C, Zhang L, Zhang Y, Li Y, Dong Z
Histology and histopathology 2021 Oct 29;:18388
Histology and histopathology 2021 Oct 29;:18388
Fructus Ligustri Lucidi aqueous extract promotes calcium balance and short-chain fatty acids production in ovariectomized rats.
Chen B, Wei J, Zhu R, Zhang H, Xia B, Liu Y, Dai X, Ye Z, Tian Y, Li R, Zhao D, Mo F, Orekhov AN, Gao S, Brὃmme D, Wang L, Zhang D
Journal of ethnopharmacology 2021 Oct 28;279:114348
Journal of ethnopharmacology 2021 Oct 28;279:114348
Dysfunctional lactate metabolism in human alveolar type II cells from idiopathic pulmonary fibrosis lung explant tissue.
Newton DA, Lottes RG, Ryan RM, Spyropoulos DD, Baatz JE
Respiratory research 2021 Oct 28;22(1):278
Respiratory research 2021 Oct 28;22(1):278
Subtractive CRISPR screen identifies the ATG16L1/vacuolar ATPase axis as required for non-canonical LC3 lipidation.
Ulferts R, Marcassa E, Timimi L, Lee LC, Daley A, Montaner B, Turner SD, Florey O, Baillie JK, Beale R
Cell reports 2021 Oct 26;37(4):109899
Cell reports 2021 Oct 26;37(4):109899
FABP4 is an independent risk factor for lymph node metastasis and poor prognosis in patients with cervical cancer.
Li G, Wu Q, Gong L, Xu X, Cai J, Xu L, Zeng Y, He X, Wang Z
Cancer cell international 2021 Oct 26;21(1):568
Cancer cell international 2021 Oct 26;21(1):568
The overexpression of Tipe2 in CRC cells suppresses survival while endogenous Tipe2 accelerates AOM/DSS induced-tumor initiation.
Li Y, Zhang N, Ma C, Xu W, Jin G, Zheng Y, Zhang L, Liu B, Gao C, Liu S
Cell death & disease 2021 Oct 26;12(11):1001
Cell death & disease 2021 Oct 26;12(11):1001
Circular RNA circPRKCI contributes to malignant progression of T-cell acute lymphoblastic leukemia by modulating miR-20a-5p/SOX4 axis.
Zheng Y, Niu B, Zhang W, Ru X, Gao Y, Li C, Wu X
Aging 2021 Oct 25;13(20):23757-23768
Aging 2021 Oct 25;13(20):23757-23768
The IFN-inducible GTPase IRGB10 regulates viral replication and inflammasome activation during influenza A virus infection in mice.
Christgen S, Place DE, Zheng M, Briard B, Yamamoto M, Kanneganti TD
European journal of immunology 2021 Oct 25;
European journal of immunology 2021 Oct 25;
Glaesserella parasuis serotype 4 HPS4-YC disrupts the integrity of the swine tracheal epithelial barrier and facilitates bacterial translocation.
Wang Q, Chang X, Liu M, Lu Q, Zhu M, Lin H, Fan H
Veterinary research 2021 Oct 21;52(1):135
Veterinary research 2021 Oct 21;52(1):135
Layered Double Hydroxide Nanoparticles with Osteogenic Effects as miRNA Carriers to Synergistically Promote Osteogenesis of MSCs.
Yang L, He X, Jing G, Wang H, Niu J, Qian Y, Wang S
ACS applied materials & interfaces 2021 Oct 20;13(41):48386-48402
ACS applied materials & interfaces 2021 Oct 20;13(41):48386-48402
The OPG/RANKL/RANK system modulates calcification of common carotid artery in simulated microgravity rats by regulating NF-κB pathway.
Liu H, Ru NY, Cai Y, Lyu Q, Guo CH, Zhou Y, Li SH, Cheng JH, Chang JR, Ma J, Su XL
Canadian journal of physiology and pharmacology 2021 Oct 20;
Canadian journal of physiology and pharmacology 2021 Oct 20;
Metformin sensitises hepatocarcinoma cells to methotrexate by targeting dihydrofolate reductase.
Wang Y, Lu H, Sun L, Chen X, Wei H, Suo C, Feng J, Yuan M, Shen S, Jia W, Wang Y, Zhang H, Li Z, Zhong X, Gao P
Cell death & disease 2021 Oct 2;12(10):902
Cell death & disease 2021 Oct 2;12(10):902
ADAR1 restricts ZBP1-mediated immune response and PANoptosis to promote tumorigenesis.
Karki R, Sundaram B, Sharma BR, Lee S, Malireddi RKS, Nguyen LN, Christgen S, Zheng M, Wang Y, Samir P, Neale G, Vogel P, Kanneganti TD
Cell reports 2021 Oct 19;37(3):109858
Cell reports 2021 Oct 19;37(3):109858
Synapse development is regulated by microglial THIK-1 K+ channels.
Izquierdo P, Shiina H, Hirunpattarasilp C, Gillis G, Attwell D
Proceedings of the National Academy of Sciences of the United States of America 2021 Oct 19;118(42)
Proceedings of the National Academy of Sciences of the United States of America 2021 Oct 19;118(42)
Agrimoniin sensitizes pancreatic cancer to apoptosis through ROS-mediated energy metabolism dysfunction.
Zhu X, Zhang Y, Wang Y, Zhang H, Wang X, Tang H, Huang H, Zhou Z, Chen B, Sun L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Oct 19;:153807
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Oct 19;:153807
LncRNA LINC00152 promotes oral squamous cell carcinoma growth via enhancing Upstream Transcription Factor 1 mediated Mitochondrial Ribosomal Protein L52 transcription.
Zou X, Hu X, He F, Zhang M, Kong X, Rui S, Liu Y, Wang L, Zheng X, Liu J, Li Z, Luo H
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2021 Oct 19;
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2021 Oct 19;
Targeting CDC7 potentiates ATR-CHK1 signaling inhibition through induction of DNA replication stress in liver cancer.
Guo Y, Wang J, Benedict B, Yang C, van Gemert F, Ma X, Gao D, Wang H, Zhang S, Lieftink C, Beijersbergen RL, Te Riele H, Qiao X, Gao Q, Sun C, Qin W, Bernards R, Wang C
Genome medicine 2021 Oct 18;13(1):166
Genome medicine 2021 Oct 18;13(1):166
Aronia melanocarpa polysaccharide ameliorates inflammation and aging in mice by modulating the AMPK/SIRT1/NF-κB signaling pathway and gut microbiota.
Zhao Y, Liu X, Zheng Y, Liu W, Ding C
Scientific reports 2021 Oct 18;11(1):20558
Scientific reports 2021 Oct 18;11(1):20558
Unexpected Implication of SRP and AGO2 in Parkinson's Disease: Involvement in Alpha-Synuclein Biogenesis.
Hernandez SM, Tikhonova EB, Baca KR, Zhao F, Zhu X, Karamyshev AL
Cells 2021 Oct 18;10(10)
Cells 2021 Oct 18;10(10)
Thromboxane A2 is involved in the development of hypertension in chronic kidney disease rats.
Hu J, Yang Z, Chen X, Kuang S, Lian Z, Ke G, Liao R, Ma J, Li S, Zhang L, Li Z, Feng Z, Liang H, Lin T, Dong W, Li R, Li Z, Chen Y, Liang X, Shi W, Deng C, Liu S
European journal of pharmacology 2021 Oct 15;909:174435
European journal of pharmacology 2021 Oct 15;909:174435
A systematic approach to decode the mechanism of Cornus in the treatment of hepatocellular carcinoma (HCC).
Shen HY, Li XQ, Fan WQ, Wang YW, Huang F, Wu JQ, Zhang W, Feng XS, Chao X
European journal of pharmacology 2021 Oct 15;909:174405
European journal of pharmacology 2021 Oct 15;909:174405
Antidepressant mechanism of catalpol: Involvement of the PI3K/Akt/Nrf2/HO-1 signaling pathway in rat hippocampus.
Wang J, Chen R, Liu C, Wu X, Zhang Y
European journal of pharmacology 2021 Oct 15;909:174396
European journal of pharmacology 2021 Oct 15;909:174396
Pharmacological activation of SIRT1 by metformin prevented trauma-induced heterotopic ossification through inhibiting macrophage mediated inflammation.
Sun Z, Li J, Luo G, Liu W, He Y, Wang F, Qian Y, Fan C
European journal of pharmacology 2021 Oct 15;909:174386
European journal of pharmacology 2021 Oct 15;909:174386
TRIM46 contributes to high glucose-induced ferroptosis and cell growth inhibition in human retinal capillary endothelial cells by facilitating GPX4 ubiquitination.
Zhang J, Qiu Q, Wang H, Chen C, Luo D
Experimental cell research 2021 Oct 15;407(2):112800
Experimental cell research 2021 Oct 15;407(2):112800
The expression of IFN-β is suppressed by the viral 3D polymerase via its impact on PGAM5 expression during enterovirus D68 infection.
Yang Z, Zheng H, Li H, Chen Y, Hou D, Fan Q, Song J, Guo L, Liu L
Virus research 2021 Oct 15;304:198549
Virus research 2021 Oct 15;304:198549
NLRP3 inflammasome blocked the glycolytic pathway via targeting to PKLR in arsenic-induced hepatic insulin resistance.
Zhang J, Qiu T, Jiang L, Wang N, Zhu Y, Yan R, Wang S, Bai J, Shi X, Yang G, Liu X, Yao X, Sun X
Ecotoxicology and environmental safety 2021 Oct 15;223:112590
Ecotoxicology and environmental safety 2021 Oct 15;223:112590
5-Aminonaphthalene derivatives as selective nonnucleoside nuclear receptor binding SET domain-protein 2 (NSD2) inhibitors for the treatment of multiple myeloma.
Wang S, Yang H, Su M, Lian F, Cong Z, Wei R, Zhou Y, Li X, Zheng X, Li C, Fu X, Han X, Shi Q, Li C, Zhang N, Geng M, Liu H, Li J, Huang X, Wang J
European journal of medicinal chemistry 2021 Oct 15;222:113592
European journal of medicinal chemistry 2021 Oct 15;222:113592
HBeAg mediates inflammatory functions of macrophages by TLR2 contributing to hepatic fibrosis.
Xie X, Lv H, Liu C, Su X, Yu Z, Song S, Bian H, Tian M, Qin C, Qi J, Zhu Q
BMC medicine 2021 Oct 15;19(1):247
BMC medicine 2021 Oct 15;19(1):247
The Timing and Effects of Low-Dose Ethanol Treatment on Acetaminophen-Induced Liver Injury.
Liu FC, Yu HP, Liao CC, Chou AH, Lee HC
Life (Basel, Switzerland) 2021 Oct 15;11(10)
Life (Basel, Switzerland) 2021 Oct 15;11(10)
Revisiting astrocyte to neuron conversion with lineage tracing in vivo.
Wang LL, Serrano C, Zhong X, Ma S, Zou Y, Zhang CL
Cell 2021 Oct 14;184(21):5465-5481.e16
Cell 2021 Oct 14;184(21):5465-5481.e16
The interaction of S100A16 and GRP78 actives endoplasmic reticulum stress-mediated through the IRE1α/XBP1 pathway in renal tubulointerstitial fibrosis.
Jin R, Zhao A, Han S, Zhang D, Sun H, Li M, Su D, Liang X
Cell death & disease 2021 Oct 13;12(10):942
Cell death & disease 2021 Oct 13;12(10):942
Shift in MSL1 alternative polyadenylation in response to DNA damage protects cancer cells from chemotherapeutic agent-induced apoptosis.
Kunisky AK, Anyaeche VI, Herron RS, Park CY, Hwang HW
Cell reports 2021 Oct 12;37(2):109815
Cell reports 2021 Oct 12;37(2):109815
Vezatin regulates seizures by controlling AMPAR-mediated synaptic activity.
Wang Y, Yuan J, Yu X, Liu X, Tan C, Chen Y, Xu T
Cell death & disease 2021 Oct 12;12(10):936
Cell death & disease 2021 Oct 12;12(10):936
Sitagliptin activates the p62-Keap1-Nrf2 signalling pathway to alleviate oxidative stress and excessive autophagy in severe acute pancreatitis-related acute lung injury.
Kong L, Deng J, Zhou X, Cai B, Zhang B, Chen X, Chen Z, Wang W
Cell death & disease 2021 Oct 11;12(10):928
Cell death & disease 2021 Oct 11;12(10):928
Triiodothyronine ameliorates silica-induced pulmonary inflammation and fibrosis in mice.
Yang M, Wang D, Gan S, Wang B, Yu L, Xie Y, Fan L, Ma J, Chen W
The Science of the total environment 2021 Oct 10;790:148041
The Science of the total environment 2021 Oct 10;790:148041
Effects of Bacillus subtilis on jejunal integrity, redox status, and microbial composition of intrauterine growth restriction suckling piglets.
Yun Y, Ji S, Yu G, Jia P, Niu Y, Zhang H, Zhang X, Wang T, Zhang L
Journal of animal science 2021 Oct 1;99(10)
Journal of animal science 2021 Oct 1;99(10)
Catalpol Weakens Depressive-like Behavior in Mice with Streptozotocin-induced Hyperglycemia via PI3K/AKT/Nrf2/HO-1 Signaling Pathway.
Wu X, Wang J, Song L, Guan Y, Cao C, Cui Y, Zhang Y, Liu C
Neuroscience 2021 Oct 1;473:102-118
Neuroscience 2021 Oct 1;473:102-118
GRIM-19 inhibits proliferation and induces apoptosis in a p53-dependent manner in colorectal cancer cells through the SIRT7/PCAF/MDM2 axis.
Wang D, Wei X, Chen X, Wang Q, Zhang J, Kalvakolanu DV, Guo B, Zhang L
Experimental cell research 2021 Oct 1;407(1):112799
Experimental cell research 2021 Oct 1;407(1):112799
EPS8 supports pancreatic cancer growth by inhibiting BMI1 mediated proteasomal degradation of ALDH7A1.
Tan M, Meng J, Sun X, Fu X, Wang R
Experimental cell research 2021 Oct 1;407(1):112782
Experimental cell research 2021 Oct 1;407(1):112782
Harpagide alleviate neuronal apoptosis and blood-brain barrier leakage by inhibiting TLR4/MyD88/NF-κB signaling pathway in Angiotensin II-induced microglial activation in vitro.
Lu Y, Hao R, Hu Y, Wei Y, Xie Y, Shen Y, Rui Q, Yu G
Chemico-biological interactions 2021 Oct 1;348:109653
Chemico-biological interactions 2021 Oct 1;348:109653
Antagonizing effects of curcumin against mercury-induced autophagic death and trace elements disorder by regulating PI3K/AKT and Nrf2 pathway in the spleen.
Zhao G, Qi L, Wang Y, Li X, Li Q, Tang X, Wang X, Wu C
Ecotoxicology and environmental safety 2021 Oct 1;222:112529
Ecotoxicology and environmental safety 2021 Oct 1;222:112529
Cadmium promotes apoptosis and inflammation via the circ08409/miR-133a/TGFB2 axis in bovine mammary epithelial cells and mouse mammary gland.
Chen Z, Liang Y, Lu Q, Nazar M, Mao Y, Aboragah A, Yang Z, Loor JJ
Ecotoxicology and environmental safety 2021 Oct 1;222:112477
Ecotoxicology and environmental safety 2021 Oct 1;222:112477
Cellular OCIAD2 protein is a proviral factor for hepatitis C virus replication.
Yang Z, Ouyang T, Aoyagi H, Wang T, Xing X, Zhang Y, Wang Y, Li Y, Aizaki H, Li S, Kong L
International journal of biological macromolecules 2021 Oct 1;188:147-159
International journal of biological macromolecules 2021 Oct 1;188:147-159
Switch receptor T3/28 improves long-term persistence and antitumor efficacy of CAR-T cells.
Zhao S, Wang C, Lu P, Lou Y, Liu H, Wang T, Yang S, Bao Z, Han L, Liang X, Ma C, Gao L
Journal for immunotherapy of cancer 2021 Nov;9(12)
Journal for immunotherapy of cancer 2021 Nov;9(12)
Nitrate increases cisplatin chemosensitivity of oral squamous cell carcinoma via REDD1/AKT signaling pathway.
Feng Y, Cao X, Zhao B, Song C, Pang B, Hu L, Zhang C, Wang J, He J, Wang S
Science China. Life sciences 2021 Nov;64(11):1814-1828
Science China. Life sciences 2021 Nov;64(11):1814-1828
Hsa-miR-372-5p regulates the NIMA related kinase 7 and IL-1β release in NK/T-cell lymphoma.
Chen Q, Liu S, Zhang K, Yu B, Zhang W, Zhang H, Chen X
Leukemia & lymphoma 2021 Nov;62(11):2648-2656
Leukemia & lymphoma 2021 Nov;62(11):2648-2656
D-mannose alleviates osteoarthritis progression by inhibiting chondrocyte ferroptosis in a HIF-2α-dependent manner.
Zhou X, Zheng Y, Sun W, Zhang Z, Liu J, Yang W, Yuan W, Yi Y, Wang J, Liu J
Cell proliferation 2021 Nov;54(11):e13134
Cell proliferation 2021 Nov;54(11):e13134
Curcumol inhibits the malignant progression of prostate cancer and regulates the PDK1/AKT/mTOR pathway by targeting miR‑9.
Sheng W, Xu W, Ding J, Li L, You X, Wu Y, He Q
Oncology reports 2021 Nov;46(5)
Oncology reports 2021 Nov;46(5)
Interleukin-17 upregulation participates in the pathogenesis of heart failure in mice via NF-κB-dependent suppression of SERCA2a and Cav1.2 expression.
Xue GL, Li DS, Wang ZY, Liu Y, Yang JM, Li CZ, Li XD, Ma JD, Zhang MM, Lu YJ, Li Y, Yang BF, Pan ZW
Acta pharmacologica Sinica 2021 Nov;42(11):1780-1789
Acta pharmacologica Sinica 2021 Nov;42(11):1780-1789
Oxidative stress-mediated apoptosis is involved in bisphenol S-induced reproductive toxicity in male C57BL/6 mice.
Dai W, He QZ, Zhu BQ, Zeng HC
Journal of applied toxicology : JAT 2021 Nov;41(11):1839-1851
Journal of applied toxicology : JAT 2021 Nov;41(11):1839-1851
Propylparaben concentrations in the urine of women and adverse effects on ovarian function in mice in vivo and ovarian cells in vitro.
Jiao L, Li S, Zhai J, Wang D, Li H, Chu W, Geng X, Du Y
Journal of applied toxicology : JAT 2021 Nov;41(11):1719-1731
Journal of applied toxicology : JAT 2021 Nov;41(11):1719-1731
Proteasome inhibition induces macrophage apoptosis via mitochondrial dysfunction.
Wang J, Wang Y, He S, Wang Z, Deng Q, Liang H
Journal of biochemical and molecular toxicology 2021 Nov;35(11):e22894
Journal of biochemical and molecular toxicology 2021 Nov;35(11):e22894
Rutaecarpine alleviates acute pancreatitis in mice and AR42J cells by suppressing the MAPK and NF-κB signaling pathways via calcitonin gene-related peptide.
Huang H, Wang M, Guo Z, Wu D, Wang H, Jia Y, Liu H, Ding J, Peng J
Phytotherapy research : PTR 2021 Nov;35(11):6472-6485
Phytotherapy research : PTR 2021 Nov;35(11):6472-6485
Icariin attenuates renal fibrosis in chronic kidney disease by inhibiting interleukin-1β/transforming growth factor-β-mediated activation of renal fibroblasts.
Wang M, Wang L, Zhou Y, Feng X, Ye C, Wang C
Phytotherapy research : PTR 2021 Nov;35(11):6204-6215
Phytotherapy research : PTR 2021 Nov;35(11):6204-6215
NudCL2 is an autophagy receptor that mediates selective autophagic degradation of CP110 at mother centrioles to promote ciliogenesis.
Liu M, Zhang W, Li M, Feng J, Kuang W, Chen X, Yang F, Sun Q, Xu Z, Hua J, Yang C, Liu W, Shu Q, Yang Y, Zhou T, Xie S
Cell research 2021 Nov;31(11):1199-1211
Cell research 2021 Nov;31(11):1199-1211
A peptide CORO1C-47aa encoded by the circular noncoding RNA circ-0000437 functions as a negative regulator in endometrium tumor angiogenesis.
Li F, Cai Y, Deng S, Yang L, Liu N, Chang X, Jing L, Zhou Y, Li H
The Journal of biological chemistry 2021 Nov;297(5):101182
The Journal of biological chemistry 2021 Nov;297(5):101182
Environmental Pollutant Benzo[a]pyrene Upregulated Long Non-coding RNA HZ07 Inhibits Trophoblast Cell Migration by Inactivating PI3K/AKT/MMP2 Signaling Pathway in Recurrent Pregnancy Loss.
Ye Y, Jiang S, Du T, Ding M, Hou M, Mi C, Liang T, Zhong H, Xie J, Xu W, Zhang H, Zhao X
Reproductive sciences (Thousand Oaks, Calif.) 2021 Nov;28(11):3085-3093
Reproductive sciences (Thousand Oaks, Calif.) 2021 Nov;28(11):3085-3093
miR‑486‑5p suppresses gastric cancer cell growth and migration through downregulation of fibroblast growth factor 9.
Wei W, Liu C, Yao R, Tan Q, Wang Q, Tian H
Molecular medicine reports 2021 Nov;24(5)
Molecular medicine reports 2021 Nov;24(5)
Low-dose exposure to black carbon significantly increase lung injury of cadmium by promoting cellular apoptosis.
Wang L, Bao S, Liu X, Wang F, Zhang J, Dang P, Wang F, Li B, Lin Y
Ecotoxicology and environmental safety 2021 Nov;224:112703
Ecotoxicology and environmental safety 2021 Nov;224:112703
Gas6/Axl signaling pathway promotes proliferation, migration and invasion and inhibits apoptosis in A549 cells.
Wang D, Bi L, Ran J, Zhang L, Xiao N, Li X
Experimental and therapeutic medicine 2021 Nov;22(5):1321
Experimental and therapeutic medicine 2021 Nov;22(5):1321
Metformin attenuates H(2)O(2)-induced osteoblast apoptosis by regulating SIRT3 via the PI3K/AKT pathway.
Yang K, Pei L, Zhou S, Tao L, Zhu Y
Experimental and therapeutic medicine 2021 Nov;22(5):1316
Experimental and therapeutic medicine 2021 Nov;22(5):1316
The anti-neoplastic activities of aloperine in HeLa cervical cancer cells are associated with inhibition of the IL-6-JAK1-STAT3 feedback loop.
Chen YD, Cai FY, Mao YZ, Yang YS, Xu K, Liu XF, Fan WW, Chen W, Jiang FQ, Zhang H
Chinese journal of natural medicines 2021 Nov;19(11):815-824
Chinese journal of natural medicines 2021 Nov;19(11):815-824
Tau phosphorylation and OPA1 proteolysis are unrelated events: Implications for Alzheimer's Disease.
Alavi MV
Biochimica et biophysica acta. Molecular cell research 2021 Nov;1868(12):119116
Biochimica et biophysica acta. Molecular cell research 2021 Nov;1868(12):119116
Chemical Constituents from the Rhizome of Ligusticum chuanxiong Hort. and Their Nrf2 Inducing Activity.
Zhang K, Fang KL, Wang T, Xu LT, Zhao Y, Wang XN, Xiang L, Shen T
Chemistry & biodiversity 2021 Nov;18(11):e2100302
Chemistry & biodiversity 2021 Nov;18(11):e2100302
Chitotriosidase attenuates brain inflammation via HDAC3/NF-κB pathway in D-galactose and aluminum-induced rat model with cognitive impairments.
Yu X, Yu W, Wu L, Yang W, Lü Y
Neuroscience research 2021 Nov;172:73-79
Neuroscience research 2021 Nov;172:73-79
The differentiation state of the Schwann cell progenitor drives phenotypic variation between two contagious cancers.
Owen RS, Ramarathinam SH, Bailey A, Gastaldello A, Hussey K, Skipp PJ, Purcell AW, Siddle HV
PLoS pathogens 2021 Nov;17(11):e1010033
PLoS pathogens 2021 Nov;17(11):e1010033
Perfluorooctane sulfonate induces autophagy-dependent lysosomal membrane permeabilization by weakened interaction between tyrosinated alpha-tubulin and spinster 1.
Dong Z, Qiu T, Zhang J, Sha S, Han X, Kang J, Shi X, Sun X, Jiang L, Yang G, Yao X, Ma Y
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Nov;157:112540
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Nov;157:112540
Gastrodin promotes hippocampal neurogenesis via PDE9-cGMP-PKG pathway in mice following cerebral ischemia.
Xiao H, Jiang Q, Qiu H, Wu K, Ma X, Yang J, Cheng O
Neurochemistry international 2021 Nov;150:105171
Neurochemistry international 2021 Nov;150:105171
Comparative proteomics reveals Cryptosporidium parvum manipulation of the host cell molecular expression and immune response.
Li T, Liu H, Jiang N, Wang Y, Wang Y, Zhang J, Shen Y, Cao J
PLoS neglected tropical diseases 2021 Nov;15(11):e0009949
PLoS neglected tropical diseases 2021 Nov;15(11):e0009949
Trophoblast-derived interleukin 9 mediates immune cell conversion and contributes to maternal-fetal tolerance.
Sun Y, Wu S, Zhou Q, Li X
Journal of reproductive immunology 2021 Nov;148:103379
Journal of reproductive immunology 2021 Nov;148:103379
Dopamine receptor 2 downregulation and brain-derived neurotrophic factor upregulation in the paraventricular nucleus are correlated with brown adipose tissue thermogenesis in rats with bilateral substantia nigra lesions.
Zhang Y, Zhou L, Lian H, Zhang Y, Tong S, Wang Z
Journal of chemical neuroanatomy 2021 Nov;117:102016
Journal of chemical neuroanatomy 2021 Nov;117:102016
miRNA-223-3p modulates ibrutinib resistance through regulation of the CHUK/Nf-κb signaling pathway in mantle cell lymphoma.
Yuan J, Zhang Q, Wu S, Yan S, Zhao R, Sun Y, Tian X, Zhou K
Experimental hematology 2021 Nov;103:52-59.e2
Experimental hematology 2021 Nov;103:52-59.e2
Isoliquiritigenin alleviates LPS/ D-GalN-induced acute liver failure by activating the PGC-1α/ Nrf2 pathway to reduce oxidative stress and inflammatory response.
Wang L, Wang X, Kong L, Wang S, Huang K, Wu J, Wang C, Sun H, Liu K, Meng Q
International immunopharmacology 2021 Nov;100:108159
International immunopharmacology 2021 Nov;100:108159
Functional role of galectin-9 in directing human innate immune reactions to Gram-negative bacteria and T cell apoptosis.
Schlichtner S, Meyer NH, Yasinska IM, Aliu N, Berger SM, Gibbs BF, Fasler-Kan E, Sumbayev VV
International immunopharmacology 2021 Nov;100:108155
International immunopharmacology 2021 Nov;100:108155
Ultrathin 2D Titanium Carbide MXene (Ti3 C2 Tx ) Nanoflakes Activate WNT/HIF-1α-Mediated Metabolism Reprogramming for Periodontal Regeneration.
Cui D, Kong N, Ding L, Guo Y, Yang W, Yan F
Advanced healthcare materials 2021 Nov;10(22):e2101215
Advanced healthcare materials 2021 Nov;10(22):e2101215
DNMT1-induced miR-378a-3p silencing promotes angiogenesis via the NF-κB signaling pathway by targeting TRAF1 in hepatocellular carcinoma.
Zhu B, Chen JJ, Feng Y, Yang JL, Huang H, Chung WY, Hu YL, Xue WJ
Journal of experimental & clinical cancer research : CR 2021 Nov 8;40(1):352
Journal of experimental & clinical cancer research : CR 2021 Nov 8;40(1):352
High throughput sequencing of whole transcriptome and construct of ceRNA regulatory network in RD cells infected with enterovirus D68.
Si J, Tang X, Xu L, Fu H, Li H, He Y, Bao J, Tang J, Li A, Lu N, Yang C
Virology journal 2021 Nov 7;18(1):216
Virology journal 2021 Nov 7;18(1):216
The histone deacetylase inhibitor belinostat ameliorates experimental autoimmune encephalomyelitis in mice by inhibiting TLR2/MyD88 and HDAC3/ NF-κB p65-mediated neuroinflammation.
Shen Y, Yang R, Zhao J, Chen M, Chen S, Ji B, Chen H, Liu D, Li L, Du G
Pharmacological research 2021 Nov 7;176:105969
Pharmacological research 2021 Nov 7;176:105969
Betaine alleviates right ventricular failure via regulation of Rho A/ROCK signaling pathway in rats with pulmonary arterial hypertension.
Lv Y, Ma P, Wang J, Xu Q, Fan J, Yan L, Ma P, Zhou R
European journal of pharmacology 2021 Nov 5;910:174311
European journal of pharmacology 2021 Nov 5;910:174311
Discovery of a potent MLL1 and WDR5 protein-protein interaction inhibitor with in vivo antitumor activity.
Chen W, Chen X, Li D, Wang X, Long G, Jiang Z, You Q, Guo X
European journal of medicinal chemistry 2021 Nov 5;223:113677
European journal of medicinal chemistry 2021 Nov 5;223:113677
NOX4-derived ROS-induced overexpression of FOXM1 regulates aerobic glycolysis in glioblastoma.
Su X, Yang Y, Yang Q, Pang B, Sun S, Wang Y, Qiao Q, Guo C, Liu H, Pang Q
BMC cancer 2021 Nov 5;21(1):1181
BMC cancer 2021 Nov 5;21(1):1181
Photobiomodulation inhibits the activation of neurotoxic microglia and astrocytes by inhibiting Lcn2/JAK2-STAT3 crosstalk after spinal cord injury in male rats.
Wang X, Li X, Zuo X, Liang Z, Ding T, Li K, Ma Y, Li P, Zhu Z, Ju C, Zhang Z, Song Z, Quan H, Zhang J, Hu X, Wang Z
Journal of neuroinflammation 2021 Nov 5;18(1):256
Journal of neuroinflammation 2021 Nov 5;18(1):256
FAK regulates cardiomyocyte mitochondrial fission and function through Drp1.
Chang YW, Song ZH, Chen CC
The FEBS journal 2021 Nov 5;
The FEBS journal 2021 Nov 5;
WFS1 functions in ER export of vesicular cargo proteins in pancreatic β-cells.
Wang L, Liu H, Zhang X, Song E, Wang Y, Xu T, Li Z
Nature communications 2021 Nov 30;12(1):6996
Nature communications 2021 Nov 30;12(1):6996
Alnustone inhibits the growth of hepatocellular carcinoma via ROS- mediated PI3K/Akt/mTOR/p70S6K axis.
Wang L, Cheng L, Ma L, Ahmad Farooqi A, Qiao G, Zhang Y, Ye H, Liu M, Huang J, Yang X, Lin X, Cao S
Phytotherapy research : PTR 2021 Nov 30;
Phytotherapy research : PTR 2021 Nov 30;
Decreased efficacy of the ketamine and scopolamine-induced sustained antidepressant-like effects in rats receiving metformin.
Chuang HW, Wei IH, Li CT, Huang CC
Pharmacological reports : PR 2021 Nov 30;
Pharmacological reports : PR 2021 Nov 30;
Hyaluronic acid hydrogel encapsulated BMP-14-modified ADSCs accelerate cartilage defect repair in rabbits.
Liu H, Rui Y, Liu J, Gao F, Jin Y
Journal of orthopaedic surgery and research 2021 Nov 3;16(1):657
Journal of orthopaedic surgery and research 2021 Nov 3;16(1):657
Taxifolin retards the D-galactose-induced aging process through inhibiting Nrf2-mediated oxidative stress and regulating the gut microbiota in mice.
Liu XL, Zhao YC, Zhu HY, Wu M, Zheng YN, Yang M, Cheng ZQ, Ding CB, Liu WC
Food & function 2021 Nov 29;12(23):12142-12158
Food & function 2021 Nov 29;12(23):12142-12158
Exosomes from dental pulp cells attenuate bone loss in mouse experimental periodontitis.
Shimizu Y, Takeda-Kawaguchi T, Kuroda I, Hotta Y, Kawasaki H, Hariyama T, Shibata T, Akao Y, Kunisada T, Tatsumi J, Tezuka KI
Journal of periodontal research 2021 Nov 26;
Journal of periodontal research 2021 Nov 26;
Golgi Phosphoprotein 3 Confers Radioresistance via Stabilizing EGFR in Lung Adenocarcinoma.
Chen G, Kong P, Yang M, Hu W, Prise KM, Yu KN, Cui S, Qin F, Meng G, Almahi WA, Nie L, Han W
International journal of radiation oncology, biology, physics 2021 Nov 26;
International journal of radiation oncology, biology, physics 2021 Nov 26;
Structure-Based Discovery of Potent CARM1 Inhibitors for Solid Tumor and Cancer Immunology Therapy.
Zhang Z, Guo Z, Xu X, Cao D, Yang H, Li Y, Shi Q, Du Z, Guo X, Wang X, Chen D, Zhang Y, Chen L, Zhou K, Li J, Geng M, Huang X, Xiong B
Journal of medicinal chemistry 2021 Nov 25;64(22):16650-16674
Journal of medicinal chemistry 2021 Nov 25;64(22):16650-16674
Proteolysis-Targeting Chimera (PROTAC) Modification of Dovitinib Enhances the Antiproliferative Effect against FLT3-ITD-Positive Acute Myeloid Leukemia Cells.
Cao S, Ma L, Liu Y, Wei M, Yao Y, Li C, Wang R, Liu N, Dong Z, Li X, Li M, Wang X, Yang C, Yang G
Journal of medicinal chemistry 2021 Nov 25;64(22):16497-16511
Journal of medicinal chemistry 2021 Nov 25;64(22):16497-16511
Carrier-Free Delivery of Ultrasmall π-Conjugated Oligomer Nanoparticles with Photothermal Conversion over 80% for Cancer Theranostics.
Zheng R, Zhao Q, Qing W, Li S, Liu Z, Li Q, Huang Y
Small (Weinheim an der Bergstrasse, Germany) 2021 Nov 25;:e2104521
Small (Weinheim an der Bergstrasse, Germany) 2021 Nov 25;:e2104521
Knockdown of GBP1 inhibits BCG-induced apoptosis in macrophage RAW 264.7 cells via p38/JNK pathway.
Wang J, Liu Z, Li W, Yu J, Zhang D
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2021 Nov 23;97:105158
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2021 Nov 23;97:105158
The deubiquitinase USP28 stabilizes the expression of RecQ family helicases and maintains the viability of triple negative breast cancer cells.
Wang J, Dong Y, Ma H, Wu L, Zhen X, Tang L, Jin J, Han S, Zhang P, Peng J
The Journal of biological chemistry 2021 Nov 22;298(1):101443
The Journal of biological chemistry 2021 Nov 22;298(1):101443
Sorafenib attenuates liver fibrosis by triggering hepatic stellate cell ferroptosis via HIF-1α/SLC7A11 pathway.
Yuan S, Wei C, Liu G, Zhang L, Li J, Li L, Cai S, Fang L
Cell proliferation 2021 Nov 22;:e13158
Cell proliferation 2021 Nov 22;:e13158
Ginsenoside Rb1 alleviates diabetic kidney podocyte injury by inhibiting aldose reductase activity.
He JY, Hong Q, Chen BX, Cui SY, Liu R, Cai GY, Guo J, Chen XM
Acta pharmacologica Sinica 2021 Nov 22;
Acta pharmacologica Sinica 2021 Nov 22;
Cadmium attenuates testosterone synthesis by promoting ferroptosis and blocking autophagosome-lysosome fusion.
Zeng L, Zhou J, Wang X, Zhang Y, Wang M, Su P
Free radical biology & medicine 2021 Nov 20;176:176-188
Free radical biology & medicine 2021 Nov 20;176:176-188
Effect of combination therapy with neural stem cell transplantation and teramethylpyrazine in rats following acute spinal cord injury.
Zhang H, Huang Z, Guo M, Meng L, Piao M, Zhang M, Yu H
Neuroreport 2021 Nov 2;32(16):1311-1319
Neuroreport 2021 Nov 2;32(16):1311-1319
HIF-1-regulated expression of calreticulin promotes breast tumorigenesis and progression through Wnt/β-catenin pathway activation.
Liu X, Xie P, Hao N, Zhang M, Liu Y, Liu P, Semenza GL, He J, Zhang H
Proceedings of the National Academy of Sciences of the United States of America 2021 Nov 2;118(44)
Proceedings of the National Academy of Sciences of the United States of America 2021 Nov 2;118(44)
MiR-29b-1-5p regulates the proliferation and differentiation of chicken primary myoblasts and analysis of its effective targets.
Li Y, Zhai B, Yuan P, Fan S, Jin W, Li W, Sun G, Tian Y, Liu X, Kang X, Li G
Poultry science 2021 Nov 2;101(2):101557
Poultry science 2021 Nov 2;101(2):101557
Sestrin2 induction contributes to anti-inflammatory responses and cell survival by globular adiponectin in macrophages.
Lee S, Pham DV, Park PH
Archives of pharmacal research 2021 Nov 19;
Archives of pharmacal research 2021 Nov 19;
Identification of proximal SUMO-dependent interactors using SUMO-ID.
Barroso-Gomila O, Trulsson F, Muratore V, Canosa I, Merino-Cacho L, Cortazar AR, Pérez C, Azkargorta M, Iloro I, Carracedo A, Aransay AM, Elortza F, Mayor U, Vertegaal ACO, Barrio R, Sutherland JD
Nature communications 2021 Nov 18;12(1):6671
Nature communications 2021 Nov 18;12(1):6671
Induction of estrogen receptor β-mediated autophagy sensitizes breast cancer cells to TAD1822-7, a novel biphenyl urea taspine derivative.
Su Q, Wu Q, Chen K, Wang J, Sarwar A, Zhang Y
Molecular biology reports 2021 Nov 18;
Molecular biology reports 2021 Nov 18;
Fluoride Stimulates Anxiety- and Depression-like Behaviors Associated with SIK2-CRTC1 Signaling Dysfunction.
Zhou G, Hu Y, Wang A, Guo M, Du Y, Gong Y, Ding L, Feng Z, Hou X, Xu K, Yu F, Li Z, Ba Y
Journal of agricultural and food chemistry 2021 Nov 17;69(45):13618-13627
Journal of agricultural and food chemistry 2021 Nov 17;69(45):13618-13627
Dendrobium officinale Polysaccharide Alleviates Intestinal Inflammation by Promoting Small Extracellular Vesicle Packaging of miR-433-3p.
Liu H, Liang J, Zhong Y, Xiao G, Efferth T, Georgiev MI, Vargas-De-La-Cruz C, Bajpai VK, Caprioli G, Liu J, Lin J, Wu H, Peng L, Li Y, Ma L, Xiao J, Wang Q
Journal of agricultural and food chemistry 2021 Nov 17;69(45):13510-13523
Journal of agricultural and food chemistry 2021 Nov 17;69(45):13510-13523
Role of Epigallocatechin Gallate in Glucose, Lipid, and Protein Metabolism and L-Theanine in the Metabolism-Regulatory Effects of Epigallocatechin Gallate.
Lin L, Zeng L, Liu A, Yuan D, Peng Y, Zhang S, Li Y, Chen J, Xiao W, Gong Z
Nutrients 2021 Nov 17;13(11)
Nutrients 2021 Nov 17;13(11)
Exopolysaccharides from Bifidobacterium animalis Ameliorate Escherichia coli-Induced IPEC-J2 Cell Damage via Inhibiting Apoptosis and Restoring Autophagy.
Yuan L, Chu B, Chen S, Li Y, Liu N, Zhu Y, Zhou D
Microorganisms 2021 Nov 16;9(11)
Microorganisms 2021 Nov 16;9(11)
Ciliary Type III Adenylyl Cyclase in the VMH Is Crucial for High-Fat Diet-Induced Obesity Mediated by Autophagy.
Yang D, Wu X, Wang W, Zhou Y, Wang Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 Nov 16;:e2102568
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 Nov 16;:e2102568
Astragalus polysaccharide prevents ferroptosis in a murine model of experimental colitis and human Caco-2 cells via inhibiting NRF2/HO-1 pathway.
Chen Y, Wang J, Li J, Zhu J, Wang R, Xi Q, Wu H, Shi T, Chen W
European journal of pharmacology 2021 Nov 15;911:174518
European journal of pharmacology 2021 Nov 15;911:174518
HMMR is a downstream target of FOXM1 in enhancing proliferation and partial epithelial-to-mesenchymal transition of bladder cancer cells.
Yang D, Ma Y, Zhao P, Ma J, He C
Experimental cell research 2021 Nov 15;408(2):112860
Experimental cell research 2021 Nov 15;408(2):112860
3-Epipachysamine B suppresses proliferation and induces apoptosis of breast cancer cell via PI3K/AKT/mTOR signaling pathway.
Zhang L, Zheng Y, Zeng L, Zhang F, Che D, Cao Z, Huang C, Xian L, Zhang X, Zhang H, Guo Z
Life sciences 2021 Nov 15;285:119995
Life sciences 2021 Nov 15;285:119995
Si-Wu-Tang facilitates ovarian function through improving ovarian microenvironment and angiogenesis in a mouse model of premature ovarian failure.
Zhou F, Song Y, Liu X, Zhang C, Li F, Hu R, Huang Y, Ma W, Song K, Zhang M
Journal of ethnopharmacology 2021 Nov 15;280:114431
Journal of ethnopharmacology 2021 Nov 15;280:114431
Protective effect of the effective part of Andrographis paniculata (Burm.f.) Nees on PM2.5-induced lung injury in rats by modulating the NF-κB pathway.
Yao H, Zhao J, Zhu L, Xie Y, Zhao N, Yao R, Sun H, Han G
Journal of ethnopharmacology 2021 Nov 15;280:114420
Journal of ethnopharmacology 2021 Nov 15;280:114420
Yi-Qi-Jian-Pi formula modulates the PI3K/AKT signaling pathway to attenuate acute-on-chronic liver failure by suppressing hypoxic injury and apoptosis in vivo and in vitro.
Tang L, Wang F, Xiao L, Shen M, Xia S, Zhang Z, Zhang F, Zheng S, Tan S
Journal of ethnopharmacology 2021 Nov 15;280:114411
Journal of ethnopharmacology 2021 Nov 15;280:114411
Cutting Edge: Caspase-8 Is a Linchpin in Caspase-3 and Gasdermin D Activation to Control Cell Death, Cytokine Release, and Host Defense during Influenza A Virus Infection.
Wang Y, Karki R, Zheng M, Kancharana B, Lee S, Kesavardhana S, Hansen BS, Pruett-Miller SM, Kanneganti TD
Journal of immunology (Baltimore, Md. : 1950) 2021 Nov 15;207(10):2411-2416
Journal of immunology (Baltimore, Md. : 1950) 2021 Nov 15;207(10):2411-2416
SARS-CoV-2 inhibits induction of the MHC class I pathway by targeting the STAT1-IRF1-NLRC5 axis.
Yoo JS, Sasaki M, Cho SX, Kasuga Y, Zhu B, Ouda R, Orba Y, de Figueiredo P, Sawa H, Kobayashi KS
Nature communications 2021 Nov 15;12(1):6602
Nature communications 2021 Nov 15;12(1):6602
Heat stress induces oxidative stress and activates the KEAP1-NFE2L2-ARE pathway in bovine endometrial epithelial cells†.
Murata H, Kunii H, Kusama K, Sakurai T, Bai H, Kawahara M, Takahashi M
Biology of reproduction 2021 Nov 15;105(5):1114-1125
Biology of reproduction 2021 Nov 15;105(5):1114-1125
Xbp1s-Ddit3 promotes MCT-induced pulmonary hypertension.
Jiang H, Ding D, He Y, Li X, Xu Y, Liu X
Clinical science (London, England : 1979) 2021 Nov 12;135(21):2467-2481
Clinical science (London, England : 1979) 2021 Nov 12;135(21):2467-2481
The Mutational Landscape of PTK7 in Congenital Scoliosis and Adolescent Idiopathic Scoliosis.
Su Z, Yang Y, Wang S, Zhao S, Zhao H, Li X, Niu Y, Deciphering Disorders Involving Scoliosis And COmorbidities Disco Study Group, Qiu G, Wu Z, Wu N, Zhang TJ
Genes 2021 Nov 12;12(11)
Genes 2021 Nov 12;12(11)
Phase separation drives RNA virus-induced activation of the NLRP6 inflammasome.
Shen C, Li R, Negro R, Cheng J, Vora SM, Fu TM, Wang A, He K, Andreeva L, Gao P, Tian Z, Flavell RA, Zhu S, Wu H
Cell 2021 Nov 11;184(23):5759-5774.e20
Cell 2021 Nov 11;184(23):5759-5774.e20
The cytotoxicity of zinc oxide nanoparticles to 3D brain organoids results from excessive intracellular zinc ions and defective autophagy.
Liu L, Wang J, Zhang J, Huang C, Yang Z, Cao Y
Cell biology and toxicology 2021 Nov 11;
Cell biology and toxicology 2021 Nov 11;
Erythritol Improves Nonalcoholic Fatty Liver Disease by Activating Nrf2 Antioxidant Capacity.
Jin M, Wei Y, Yu H, Ma X, Yan S, Zhao L, Ding L, Cheng J, Feng H
Journal of agricultural and food chemistry 2021 Nov 10;69(44):13080-13092
Journal of agricultural and food chemistry 2021 Nov 10;69(44):13080-13092
AICAR enhances the cytotoxicity of PFKFB3 inhibitor in an AMPK signaling-independent manner in colorectal cancer cells.
Yan S, Yuan D, Li Q, Li S, Zhang F
Medical oncology (Northwood, London, England) 2021 Nov 10;39(1):10
Medical oncology (Northwood, London, England) 2021 Nov 10;39(1):10
Isorhapontigenin (ISO) inhibits EMT through FOXO3A/METTL14/VIMENTIN pathway in bladder cancer cells.
Zhang N, Hua X, Tu H, Li J, Zhang Z, Max C
Cancer letters 2021 Nov 1;520:400-408
Cancer letters 2021 Nov 1;520:400-408
SAA1 is transcriptionally activated by STAT3 and accelerates renal interstitial fibrosis by inducing endoplasmic reticulum stress.
Zhang F, Zhou X, Zou H, Liu L, Li X, Ruan Y, Xie Y, Shi M, Xiao Y, Wang Y, Zhou Y, Wu Y, Guo B
Experimental cell research 2021 Nov 1;408(1):112856
Experimental cell research 2021 Nov 1;408(1):112856
Competing endogenous RNA network associated with oxygen-induced retinopathy: Expression of the network and identification of the MALAT1/miR-124-3p/EGR1 regulatory axis.
Xia F, Xu Y, Zhang X, Lyu J, Zhao P
Experimental cell research 2021 Nov 1;408(1):112783
Experimental cell research 2021 Nov 1;408(1):112783
A naturally occurring FXR agonist, alisol B 23-acetate, protects against renal ischemia-reperfusion injury.
Luan ZL, Ming WH, Sun XW, Zhang C, Zhou Y, Zheng F, Yang YL, Guan YF, Zhang XY
American journal of physiology. Renal physiology 2021 Nov 1;321(5):F617-F628
American journal of physiology. Renal physiology 2021 Nov 1;321(5):F617-F628
Vps13D functions in a Pink1-dependent and Parkin-independent mitophagy pathway.
Shen JL, Fortier TM, Wang R, Baehrecke EH
The Journal of cell biology 2021 Nov 1;220(11)
The Journal of cell biology 2021 Nov 1;220(11)
Role of Lysocardiolipin Acyltransferase in Cigarette Smoke-Induced Lung Epithelial Cell Mitochondrial ROS, Mitochondrial Dynamics, and Apoptosis.
Bandela M, Suryadevara V, Fu P, Reddy SP, Bikkavilli K, Huang LS, Dhavamani S, Subbaiah PV, Singla S, Dudek SM, Ware LB, Ramchandran R, Natarajan V
Cell biochemistry and biophysics 2021 Nov 1;
Cell biochemistry and biophysics 2021 Nov 1;
Deleterious impact of nerve growth factor precursor (proNGF) on bladder urothelial and smooth muscle cells.
Mossa AH, Abdaem J, Cammisotto P, Campeau L
Cellular signalling 2021 May;81:109936
Cellular signalling 2021 May;81:109936
Efficient Killing of Multidrug-Resistant Internalized Bacteria by AIEgens In Vivo.
Li Y, Liu F, Zhang J, Liu X, Xiao P, Bai H, Chen S, Wang D, Sung SHP, Kwok RTK, Shen J, Zhu K, Tang BZ
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 May;8(9):2001750
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 May;8(9):2001750
Amelioration of Murine Macrophage Activation Syndrome by Monomethyl Fumarate in Both a Heme Oxygenase 1-Dependent and Heme Oxygenase 1-Independent Manner.
Biswas C, Chu N, Burn TN, Kreiger PA, Behrens EM
Arthritis & rheumatology (Hoboken, N.J.) 2021 May;73(5):885-895
Arthritis & rheumatology (Hoboken, N.J.) 2021 May;73(5):885-895
Elevated type I interferon responses potentiate metabolic dysfunction, inflammation, and accelerated aging in mtDNA mutator mice.
Lei Y, Guerra Martinez C, Torres-Odio S, Bell SL, Birdwell CE, Bryant JD, Tong CW, Watson RO, West LC, West AP
Science advances 2021 May;7(22)
Science advances 2021 May;7(22)
Novel Japanese encephalitis virus NS1-based vaccine: Truncated NS1 fused with E. coli heat labile enterotoxin B subunit.
Wan J, Wang T, Xu J, Ouyang T, Wang Q, Zhang Y, Weng S, Li Y, Wang Y, Xin X, Wang X, Li S, Kong L
EBioMedicine 2021 May;67:103353
EBioMedicine 2021 May;67:103353
Cu-induced mitochondrial dysfunction is mediated by abnormal mitochondrial fission through oxidative stress in primary chicken embryo hepatocytes.
Wu L, Kang Z, Qiao N, Wang C, Tang Z
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2021 May;65:126721
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2021 May;65:126721
Changes of lipid profiles in human umbilical vein endothelial cells exposed to zirconia nanoparticles with or without the presence of free fatty acids.
Cheng X, Guo H, Xian Y, Xie X
Journal of applied toxicology : JAT 2021 May;41(5):765-774
Journal of applied toxicology : JAT 2021 May;41(5):765-774
Comparison of toxicity of Ti3 C2 and Nb2 C Mxene quantum dots (QDs) to human umbilical vein endothelial cells.
Gu M, Dai Z, Yan X, Ma J, Niu Y, Lan W, Wang X, Xu Q
Journal of applied toxicology : JAT 2021 May;41(5):745-754
Journal of applied toxicology : JAT 2021 May;41(5):745-754
Long non-coding RNA LEISA promotes progression of lung adenocarcinoma via enhancing interaction between STAT3 and IL-6 promoter.
Wu S, Liu B, Zhang Y, Hong R, Liu S, Xiang T, Tao T, Cai J, Wu J, Li M, Guan H
Oncogene 2021 May;40(19):3449-3459
Oncogene 2021 May;40(19):3449-3459
miR-509-3p Suppresses Migration, Invasion, and Epithelial- Mesenchymal Transition in Melanoma Cells by Targeting Collagen Triple Helix Repeat Containing 1.
Yuan K, Sun Y, Ji Y
Balkan medical journal 2021 May;38(3):177-182
Balkan medical journal 2021 May;38(3):177-182
Cross-talk Between Histone and DNA Methylation Mediates Bone Loss in Hind Limb Unloading.
Li B, Zhao J, Ma J, Chen W, Zhou C, Wei W, Li S, Li G, Xin G, Zhang Y, Liu J, Wang Y, Ma X
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2021 May;36(5):956-967
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2021 May;36(5):956-967
Long noncoding RNA DUXAP10 promotes the stemness of glioma cells by recruiting HuR to enhance Sox12 mRNA stability.
Wu B, Yang C, Fang Y, Ding W, Zhang Y
Environmental toxicology 2021 May;36(5):840-849
Environmental toxicology 2021 May;36(5):840-849
Glucose-dependent insulinotropic polypeptide modifies adipose plasticity and promotes beige adipogenesis of human omental adipose-derived stem cells.
Chen X, He X, Guo Y, Liu L, Li H, Tan J, Feng W, Guan H, Cao X, Xiao H, Li Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 May;35(5):e21534
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 May;35(5):e21534
Loss of ferroportin induces memory impairment by promoting ferroptosis in Alzheimer's disease.
Bao WD, Pang P, Zhou XT, Hu F, Xiong W, Chen K, Wang J, Wang F, Xie D, Hu YZ, Han ZT, Zhang HH, Wang WX, Nelson PT, Chen JG, Lu Y, Man HY, Liu D, Zhu LQ
Cell death and differentiation 2021 May;28(5):1548-1562
Cell death and differentiation 2021 May;28(5):1548-1562
Cholesterol 25-hydroxylase inhibits Senecavirus A replication by enzyme activity-dependent and independent mechanisms.
Zhu H, Yan J, Liu X, Li L, Liu W, Wang X, Jiang P, Bai J
Veterinary microbiology 2021 May;256:109038
Veterinary microbiology 2021 May;256:109038
IL-1/IL-1R signaling induced by all-trans-retinal contributes to complement alternative pathway activation in retinal pigment epithelium.
Cheng X, He D, Liao C, Lin S, Tang L, Wang YL, Hu J, Li W, Liu Z, Wu Y, Liao Y
Journal of cellular physiology 2021 May;236(5):3660-3674
Journal of cellular physiology 2021 May;236(5):3660-3674
Free Deoxycholic Acid Exacerbates Vascular Calcification in CKD through ER Stress-Mediated ATF4 Activation.
Miyazaki-Anzai S, Masuda M, Shiozaki Y, Keenan AL, Chonchol M, Kremoser C, Miyazaki M
Kidney360 2021 May;2(5):857-868
Kidney360 2021 May;2(5):857-868
Long non-coding RNA PCA3 inhibits lipid accumulation and atherosclerosis through the miR-140-5p/RFX7/ABCA1 axis.
Zhao ZW, Zhang M, Liao LX, Zou J, Wang G, Wan XJ, Zhou L, Li H, Qin YS, Yu XH, Tang CK
Biochimica et biophysica acta. Molecular and cell biology of lipids 2021 May;1866(5):158904
Biochimica et biophysica acta. Molecular and cell biology of lipids 2021 May;1866(5):158904
Anti-osteoporotic effects of alisol C 23-acetate via osteoclastogenesis inhibition.
Jia X, Zhu H, Li G, Lan M, Li X, Huang M, Xu W, Wu S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 May;137:111321
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 May;137:111321
SREBP1/FASN/cholesterol axis facilitates radioresistance in colorectal cancer.
Jin Y, Chen Z, Dong J, Wang B, Fan S, Yang X, Cui M
FEBS open bio 2021 May;11(5):1343-1352
FEBS open bio 2021 May;11(5):1343-1352
Multi-omics approaches identify SF3B3 and SIRT3 as candidate autophagic regulators and druggable targets in invasive breast carcinoma.
Zhang S, Zhang J, An Y, Zeng X, Qin Z, Zhao Y, Xu H, Liu B
Acta pharmaceutica Sinica. B 2021 May;11(5):1227-1245
Acta pharmaceutica Sinica. B 2021 May;11(5):1227-1245
The role of PKA/PP2B-mediated Drp1 phosphorylation and the subsequent EGFR inhibition in Cr(VI)-induced premature senescence.
Li S, Ma Y, Liang Y, Liang N, Ye S, Xiao F
Ecotoxicology and environmental safety 2021 May 7;218:112300
Ecotoxicology and environmental safety 2021 May 7;218:112300
De novo purine biosynthesis is a major driver of chemoresistance in glioblastoma.
Shireman JM, Atashi F, Lee G, Ali ES, Saathoff MR, Park CH, Savchuk S, Baisiwala S, Miska J, Lesniak MS, James CD, Stupp R, Kumthekar P, Horbinski CM, Ben-Sahra I, Ahmed AU
Brain : a journal of neurology 2021 May 7;144(4):1230-1246
Brain : a journal of neurology 2021 May 7;144(4):1230-1246
Oxidative stress induced by NOX2 contributes to neuropathic pain via plasma membrane translocation of PKCε in rat dorsal root ganglion neurons.
Xu J, Wu S, Wang J, Wang J, Yan Y, Zhu M, Zhang D, Jiang C, Liu T
Journal of neuroinflammation 2021 May 6;18(1):106
Journal of neuroinflammation 2021 May 6;18(1):106
Redd1 knockdown prevents doxorubicin-induced cardiac senescence.
Huang P, Bai L, Liu L, Fu J, Wu K, Liu H, Liu Y, Qi B, Qi B
Aging 2021 May 6;13(10):13788-13806
Aging 2021 May 6;13(10):13788-13806
Circular RNA Calm4 Regulates Hypoxia-Induced Pulmonary Arterial Smooth Muscle Cells Pyroptosis via the Circ-Calm4/miR-124-3p/PDCD6 Axis.
Jiang Y, Liu H, Yu H, Zhou Y, Zhang J, Xin W, Li Y, He S, Ma C, Zheng X, Zhang L, Zhao X, Wu B, Jiang C, Zhu D
Arteriosclerosis, thrombosis, and vascular biology 2021 May 5;41(5):1675-1693
Arteriosclerosis, thrombosis, and vascular biology 2021 May 5;41(5):1675-1693
Evaluation of Stable LifeAct-mRuby2- and LAMP1-NeonGreen Expressing A549 Cell Lines for Investigation of Aspergillus fumigatus Interaction with Pulmonary Cells.
Schiefermeier-Mach N, Moresco V, Geley S, Heinrich L, Lechner L, Oberhauser H, Perkhofer S
International journal of molecular sciences 2021 May 31;22(11)
International journal of molecular sciences 2021 May 31;22(11)
High-fat diet impairs ferroptosis and promotes cancer invasiveness via downregulating tumor suppressor ACSL4 in lung adenocarcinoma.
Zhang Y, Li S, Li F, Lv C, Yang QK
Biology direct 2021 May 31;16(1):10
Biology direct 2021 May 31;16(1):10
FKBP52 overexpression accelerates hippocampal-dependent memory impairments in a tau transgenic mouse model.
Criado-Marrero M, Gebru NT, Gould LA, Blazier DM, Vidal-Aguiar Y, Smith TM, Abdelmaboud SS, Shelton LB, Wang X, Dahrendorff J, Beaulieu-Abdelahad D, Dickey CA, Blair LJ
NPJ aging and mechanisms of disease 2021 May 3;7(1):9
NPJ aging and mechanisms of disease 2021 May 3;7(1):9
Ribonucleic Acid Export 1 Is a Kinetochore-Associated Protein That Participates in Chromosome Alignment in Mouse Oocytes.
Chen F, Jiao XF, Meng F, Wang YS, Ding ZM, Miao YL, Xiong JJ, Huo LJ
International journal of molecular sciences 2021 May 3;22(9)
International journal of molecular sciences 2021 May 3;22(9)
Effect of circular RNA, mmu_circ_0000296, on neuronal apoptosis in chronic cerebral ischaemia via the miR-194-5p/Runx3/Sirt1 axis.
Huang K, Yang C, Zheng J, Liu X, Liu J, Che D, Xue Y, An P, Wang D, Ruan X, Yu B
Cell death discovery 2021 May 29;7(1):124
Cell death discovery 2021 May 29;7(1):124
Oocyte-secreted factors strongly stimulate sFRP4 expression in human cumulus cells.
Esfandyari S, Winston NJ, Fierro MA, Scoccia H, Stocco C
Molecular human reproduction 2021 May 29;27(6)
Molecular human reproduction 2021 May 29;27(6)
Lipoxin A4 protects primary spinal cord neurons from Erastin-induced ferroptosis by activating the Akt/Nrf2/HO-1 signaling pathway.
Wei N, Lu T, Yang L, Dong Y, Liu X
FEBS open bio 2021 May 28;
FEBS open bio 2021 May 28;
Vertebrate cells differentially interpret ciliary and extraciliary cAMP.
Truong ME, Bilekova S, Choksi SP, Li W, Bugaj LJ, Xu K, Reiter JF
Cell 2021 May 27;184(11):2911-2926.e18
Cell 2021 May 27;184(11):2911-2926.e18
Genome-wide CRISPRi screening identifies OCIAD1 as a prohibitin client and regulatory determinant of mitochondrial Complex III assembly in human cells.
Le Vasseur M, Friedman J, Jost M, Xu J, Yamada J, Kampmann M, Horlbeck MA, Salemi MR, Phinney BS, Weissman JS, Nunnari J
eLife 2021 May 26;10
eLife 2021 May 26;10
Evaluation of the nephrotoxicity and safety of low-dose aristolochic acid, extending to the use of Xixin (Asurum), by determination of methylglyoxal and d-lactate.
Lin CE, Lin PY, Yang WC, Huang YS, Lin TY, Chen CM, Chen HS, Lee JA, Chen SM
Journal of ethnopharmacology 2021 May 23;272:113945
Journal of ethnopharmacology 2021 May 23;272:113945
Downregulation of CD151 restricts VCAM-1 mediated leukocyte infiltration to reduce neurobiological injuries after experimental stroke.
Gao C, Jia W, Xu W, Wu Q, Wu J
Journal of neuroinflammation 2021 May 22;18(1):118
Journal of neuroinflammation 2021 May 22;18(1):118
Maternal folic acid supplementation prevents autistic behaviors in a rat model induced by prenatal exposure to valproic acid.
Di Y, Li Z, Li J, Cheng Q, Zheng Q, Zhai C, Kang M, Wei C, Lan J, Fan J, Ren W, Tian Y
Food & function 2021 May 21;12(10):4544-4555
Food & function 2021 May 21;12(10):4544-4555
USP18 positively regulates innate antiviral immunity by promoting K63-linked polyubiquitination of MAVS.
Hou J, Han L, Zhao Z, Liu H, Zhang L, Ma C, Yi F, Liu B, Zheng Y, Gao C
Nature communications 2021 May 20;12(1):2970
Nature communications 2021 May 20;12(1):2970
The miR-378c-Samd1 circuit promotes phenotypic modulation of vascular smooth muscle cells and foam cells formation in atherosclerosis lesions.
Tian S, Cao Y, Wang J, Bi Y, Zhong J, Meng X, Sun W, Yang R, Gan L, Wang X, Li H, Wang R
Scientific reports 2021 May 18;11(1):10548
Scientific reports 2021 May 18;11(1):10548
Mir-139-5p inhibits glioma cell proliferation and progression by targeting GABRA1.
Wang L, Liu Y, Yu Z, Gong J, Deng Z, Ren N, Zhong Z, Cai H, Tang Z, Cheng H, Chen S, He Z
Journal of translational medicine 2021 May 17;19(1):213
Journal of translational medicine 2021 May 17;19(1):213
LncRNA ZNF674-AS1 regulates granulosa cell glycolysis and proliferation by interacting with ALDOA.
Li D, Wang X, Li G, Dang Y, Zhao S, Qin Y
Cell death discovery 2021 May 16;7(1):107
Cell death discovery 2021 May 16;7(1):107
NT5DC2 promotes leiomyosarcoma tumour cell growth via stabilizing unpalmitoylated TEAD4 and generating a positive feedback loop.
Hu B, Zhou S, Hu X, Zhang H, Lan X, Li M, Wang Y, Hu Q
Journal of cellular and molecular medicine 2021 May 16;
Journal of cellular and molecular medicine 2021 May 16;
Exercise improves lipid droplet metabolism disorder through activation of AMPK-mediated lipophagy in NAFLD.
Li H, Dun Y, Zhang W, You B, Liu Y, Fu S, Qiu L, Cheng J, Ripley-Gonzalez JW, Liu S
Life sciences 2021 May 15;273:119314
Life sciences 2021 May 15;273:119314
SET8 mitigates hepatic ischemia/reperfusion injury in mice by suppressing MARK4/NLRP3 inflammasome pathway.
Luo Y, Huang Z, Mou T, Pu J, Li T, Li Z, Yang H, Yan P, Wu Z, Wu Q
Life sciences 2021 May 15;273:119286
Life sciences 2021 May 15;273:119286
Purification, structural characterization, and PCSK9 secretion inhibitory effect of the novel alkali-extracted polysaccharide from Cordyceps militaris.
Wang J, Wang Y, Yang X, Lin P, Liu N, Li X, Zhang B, Guo S
International journal of biological macromolecules 2021 May 15;179:407-417
International journal of biological macromolecules 2021 May 15;179:407-417
Asenapine maleate inhibits angiotensin II-induced proliferation and activation of cardiac fibroblasts via the ROS/TGFβ1/MAPK signaling pathway.
Wu HH, Meng TT, Chen JM, Meng FL, Wang SY, Liu RH, Chen JN, Ning B, Li Y, Su GH
Biochemical and biophysical research communications 2021 May 14;553:172-179
Biochemical and biophysical research communications 2021 May 14;553:172-179
Hyperactivation of HER2-SHCBP1-PLK1 axis promotes tumor cell mitosis and impairs trastuzumab sensitivity to gastric cancer.
Shi W, Zhang G, Ma Z, Li L, Liu M, Qin L, Yu Z, Zhao L, Liu Y, Zhang X, Qin J, Ye H, Jiang X, Zhou H, Sun H, Jiao Z
Nature communications 2021 May 14;12(1):2812
Nature communications 2021 May 14;12(1):2812
trans-Fatty acids promote p53-dependent apoptosis triggered by cisplatin-induced DNA interstrand crosslinks via the Nox-RIP1-ASK1-MAPK pathway.
Hirata Y, Takahashi M, Yamada Y, Matsui R, Inoue A, Ashida R, Noguchi T, Matsuzawa A
Scientific reports 2021 May 14;11(1):10350
Scientific reports 2021 May 14;11(1):10350
A subcellular map of the human kinome.
Zhang H, Cao X, Tang M, Zhong G, Si Y, Li H, Zhu F, Liao Q, Li L, Zhao J, Feng J, Li S, Wang C, Kaulich M, Wang F, Chen L, Li L, Xia Z, Liang T, Lu H, Feng XH, Zhao B
eLife 2021 May 14;10
eLife 2021 May 14;10
Berberine-photodynamic therapy sensitizes melanoma cells to cisplatin-induced apoptosis through ROS-mediated P38 MAPK pathways.
Wang X, Gong Q, Song C, Fang J, Yang Y, Liang X, Huang X, Liu J
Toxicology and applied pharmacology 2021 May 1;418:115484
Toxicology and applied pharmacology 2021 May 1;418:115484
High fat suppresses SOD1 activity by reducing copper chaperone for SOD1 associated with neurodegeneration and memory decline.
Lu P, Yan HJ, Yang C, Feng WC, Hu F, Wu YY, Sun WW, Gao MM, Long YS
Life sciences 2021 May 1;272:119243
Life sciences 2021 May 1;272:119243
Short-term but not long-term high fat diet feeding protects against pressure overload-induced heart failure through activation of mitophagy.
Tan Y, Li M, Wu G, Lou J, Feng M, Xu J, Zhou J, Zhang P, Yang H, Dong L, Li J, Zhang X, Gao F
Life sciences 2021 May 1;272:119242
Life sciences 2021 May 1;272:119242
6-Gingerol attenuates ventilator-induced lung injury via anti-inflammation and antioxidative stress by modulating the PPARγ/NF-κBsignalling pathway in rats.
Hong W, Zhi FX, Kun TH, Hua FJ, Huan Ling L, Fang F, Wen C, Jie W, Yang LC
International immunopharmacology 2021 Mar;92:107367
International immunopharmacology 2021 Mar;92:107367
Total glycosides from stems of Cistanche tubulosa alleviate depression-like behaviors: bidirectional interaction of the phytochemicals and gut microbiota.
Fan L, Peng Y, Wang J, Ma P, Zhao L, Li X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Mar;83:153471
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Mar;83:153471
Androgen Receptor Stimulates Hexokinase 2 and Induces Glycolysis by PKA/CREB Signaling in Hepatocellular Carcinoma.
Sun RF, Zhao CY, Chen S, Yu W, Zhou MM, Gao CR
Digestive diseases and sciences 2021 Mar;66(3):802-813
Digestive diseases and sciences 2021 Mar;66(3):802-813
Circadian clock genes promote glioma progression by affecting tumour immune infiltration and tumour cell proliferation.
Wang Z, Su G, Dai Z, Meng M, Zhang H, Fan F, Liu Z, Zhang L, Weygant N, He F, Fang N, Zhang L, Cheng Q
Cell proliferation 2021 Mar;54(3):e12988
Cell proliferation 2021 Mar;54(3):e12988
Nbs1-mediated DNA damage repair pathway regulates haematopoietic stem cell development and embryonic haematopoiesis.
Chen Y, Sun J, Ju Z, Wang ZQ, Li T
Cell proliferation 2021 Mar;54(3):e12972
Cell proliferation 2021 Mar;54(3):e12972
MiR-520a-3p inhibits malignant progression of epithelial ovarian cancer by targeting SUV39H1 expression.
Li J, Shao W, Zhao J
Human cell 2021 Mar;34(2):570-578
Human cell 2021 Mar;34(2):570-578
Oncogenic AURKA-enhanced N6-methyladenosine modification increases DROSHA mRNA stability to transactivate STC1 in breast cancer stem-like cells.
Peng F, Xu J, Cui B, Liang Q, Zeng S, He B, Zou H, Li M, Zhao H, Meng Y, Chen J, Liu B, Lv S, Chu P, An F, Wang Z, Huang J, Zhan Y, Liao Y, Lu J, Xu L, Zhang J, Sun Z, Li Z, Wang F, Lam EW, Liu Q
Cell research 2021 Mar;31(3):345-361
Cell research 2021 Mar;31(3):345-361
Chondrocyte ferroptosis contribute to the progression of osteoarthritis.
Yao X, Sun K, Yu S, Luo J, Guo J, Lin J, Wang G, Guo Z, Ye Y, Guo F
Journal of orthopaedic translation 2021 Mar;27:33-43
Journal of orthopaedic translation 2021 Mar;27:33-43
miR-130b-3p regulates M1 macrophage polarization via targeting IRF1.
Guo Q, Zhu X, Wei R, Zhao L, Zhang Z, Yin X, Zhang Y, Chu C, Wang B, Li X
Journal of cellular physiology 2021 Mar;236(3):2008-2022
Journal of cellular physiology 2021 Mar;236(3):2008-2022
Apoptosis inhibition is involved in improvement of sevoflurane-induced cognitive impairment following normobaric hyperoxia preconditioning in aged rats.
Wang Y, Yin CP, Tai YL, Zhao ZJ, Hou ZY, Wang QJ
Experimental and therapeutic medicine 2021 Mar;21(3):203
Experimental and therapeutic medicine 2021 Mar;21(3):203
Regulation of ARL2 in colorectal cancer cell proliferation and tumorigenicity, and its negative association with AXL.
Pang X, Wang Y, Miao B, Fei S, Chen W
Oncology letters 2021 Mar;21(3):196
Oncology letters 2021 Mar;21(3):196
Three phytosterols from sweet potato inhibit MCF7-xenograft-tumor growth through modulating gut microbiota homeostasis and SCFAs secretion.
Han B, Jiang P, Jiang L, Li X, Ye X
Food research international (Ottawa, Ont.) 2021 Mar;141:110147
Food research international (Ottawa, Ont.) 2021 Mar;141:110147
d-Mannose suppresses osteoarthritis development in vivo and delays IL-1β-induced degeneration in vitro by enhancing autophagy activated via the AMPK pathway.
Lin Z, Miao J, Zhang T, He M, Zhou X, Zhang H, Gao Y, Bai L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Mar;135:111199
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Mar;135:111199
Gasdermin D Protects Mouse Podocytes Against High-Glucose-Induced Inflammation and Apoptosis via the C-Jun N-Terminal Kinase (JNK) Pathway.
Li H, Zhao K, Li Y
Medical science monitor : international medical journal of experimental and clinical research 2021 Mar 9;27:e928411
Medical science monitor : international medical journal of experimental and clinical research 2021 Mar 9;27:e928411
Plumbagin, a Biomolecule with (Anti)Osteoclastic Properties.
Sultanli S, Ghumnani S, Ashma R, Kubatzky KF
International journal of molecular sciences 2021 Mar 9;22(5)
International journal of molecular sciences 2021 Mar 9;22(5)
Expression of Talin-1 in endometriosis and its possible role in pathogenesis.
Tang X, Li Q, Li L, Jiang J
Reproductive biology and endocrinology : RB&E 2021 Mar 9;19(1):42
Reproductive biology and endocrinology : RB&E 2021 Mar 9;19(1):42
lncRNA GCAT1 is involved in premature ovarian insufficiency by regulating p27 translation in GCs via competitive binding to PTBP1.
Li D, Wang X, Dang Y, Zhang X, Zhao S, Lu G, Chan WY, Leung PCK, Qin Y
Molecular therapy. Nucleic acids 2021 Mar 5;23:132-141
Molecular therapy. Nucleic acids 2021 Mar 5;23:132-141
Combining combretastatin A4 phosphate with ginsenoside Rd synergistically inhibited hepatocellular carcinoma by reducing HIF-1α via PI3K/AKT/mTOR signalling pathway.
Yang X, Gao M, Miao M, Jiang C, Zhang D, Yin Z, Ni Y, Chen J, Zhang J
The Journal of pharmacy and pharmacology 2021 Mar 4;73(2):263-271
The Journal of pharmacy and pharmacology 2021 Mar 4;73(2):263-271
PUMA facilitates EMI1-promoted cytoplasmic Rad51 ubiquitination and inhibits DNA repair in stem and progenitor cells.
Kang JW, Zhan Z, Ji G, Sang Y, Zhou D, Li Y, Feng H, Cheng T
Signal transduction and targeted therapy 2021 Mar 31;6(1):129
Signal transduction and targeted therapy 2021 Mar 31;6(1):129
MYC promotes cancer progression by modulating m6 A modifications to suppress target gene translation.
Wu G, Suo C, Yang Y, Shen S, Sun L, Li ST, Zhou Y, Yang D, Wang Y, Cai Y, Wang N, Zhang H, Yang YG, Cao J, Gao P
EMBO reports 2021 Mar 3;22(3):e51519
EMBO reports 2021 Mar 3;22(3):e51519
The CREB/KMT5A complex regulates PTP1B to modulate high glucose-induced endothelial inflammatory factor levels in diabetic nephropathy.
Huang T, Li X, Wang F, Lu L, Hou W, Zhu M, Miao C
Cell death & disease 2021 Mar 29;12(4):333
Cell death & disease 2021 Mar 29;12(4):333
Profiling PRMT methylome reveals roles of hnRNPA1 arginine methylation in RNA splicing and cell growth.
Li WJ, He YH, Yang JJ, Hu GS, Lin YA, Ran T, Peng BL, Xie BL, Huang MF, Gao X, Huang HH, Zhu HH, Ye F, Liu W
Nature communications 2021 Mar 29;12(1):1946
Nature communications 2021 Mar 29;12(1):1946
Hispidulin inhibits proliferation, migration, and invasion by promoting autophagy via regulation of PPARγ activation in prostate cancer cells and xenograft models.
Wang Y, Guo S, Jia Y, Yu X, Mou R, Li X
Bioscience, biotechnology, and biochemistry 2021 Mar 24;85(4):786-797
Bioscience, biotechnology, and biochemistry 2021 Mar 24;85(4):786-797
Effects of transforming growth factor-β1 on odontoblastic differentiation in dental papilla cells is determined by IPO7 expression level.
Zhang Y, Zhang H, Yuan G, Yang G
Biochemical and biophysical research communications 2021 Mar 19;545:105-111
Biochemical and biophysical research communications 2021 Mar 19;545:105-111
hPER3 promotes adipogenesis via hHSP90AA1-mediated inhibition of Notch1 pathway.
Wan X, Zhu L, Zhao L, Peng L, Xiong J, Yang W, Yuan J, Liang F, Zhang K, Chen K
Cell death & disease 2021 Mar 19;12(4):301
Cell death & disease 2021 Mar 19;12(4):301
Identifying SLC27A5 as a potential prognostic marker of hepatocellular carcinoma by weighted gene co-expression network analysis and in vitro assays.
Zhang F, Xue M, Jiang X, Yu H, Qiu Y, Yu J, Yang F, Bao Z
Cancer cell international 2021 Mar 17;21(1):174
Cancer cell international 2021 Mar 17;21(1):174
PEG-GO@XN nanocomposite suppresses breast cancer metastasis via inhibition of mitochondrial oxidative phosphorylation and blockade of epithelial-to-mesenchymal transition.
Zhang J, Yan L, Wei P, Zhou R, Hua C, Xiao M, Tu Y, Gu Z, Wei T
European journal of pharmacology 2021 Mar 15;895:173866
European journal of pharmacology 2021 Mar 15;895:173866
PCGF3 promotes the proliferation and migration of non-small cell lung cancer cells via the PI3K/AKT signaling pathway.
Hu Y, Cheng Y, Jiang X, Zhang Y, Wang H, Ren H, Xu Y, Jiang J, Wang Q, Su H, Zhang B, Qiu X
Experimental cell research 2021 Mar 15;400(2):112496
Experimental cell research 2021 Mar 15;400(2):112496
The Effect of Hispidulin, a Flavonoid from Salvia plebeia, on Human Nasopharyngeal Carcinoma CNE-2Z Cell Proliferation, Migration, Invasion, and Apoptosis.
Dai Y, Sun X, Li B, Ma H, Wu P, Zhang Y, Zhu M, Li HM, Qin M, Wu CZ
Molecules (Basel, Switzerland) 2021 Mar 14;26(6)
Molecules (Basel, Switzerland) 2021 Mar 14;26(6)
Citrus Alkaline Extracts Inhibit Senescence of A549 Cells to Alleviate Pulmonary Fibrosis via the β-Catenin/P53 Pathway.
Han D, Xu Y, Peng WP, Feng F, Wang Z, Gu C, Zhou X
Medical science monitor : international medical journal of experimental and clinical research 2021 Mar 12;27:e928547
Medical science monitor : international medical journal of experimental and clinical research 2021 Mar 12;27:e928547
Gastrodin ameliorates learning and memory impairment in rats with vascular dementia by promoting autophagy flux via inhibition of the Ca2+/CaMKII signal pathway.
Chen TT, Zhou X, Xu YN, Li Y, Wu XY, Xiang Q, Fu LY, Hu XX, Tao L, Shen XC
Aging 2021 Mar 10;13(7):9542-9565
Aging 2021 Mar 10;13(7):9542-9565
Cytotoxicity mechanisms of plumbagin in drug-resistant tongue squamous cell carcinoma.
Xue D, Zhou X, Qiu J
The Journal of pharmacy and pharmacology 2021 Mar 1;73(1):98-109
The Journal of pharmacy and pharmacology 2021 Mar 1;73(1):98-109
The deubiquitylase USP9X controls ribosomal stalling.
Clancy A, Heride C, Pinto-Fernández A, Elcocks H, Kallinos A, Kayser-Bricker KJ, Wang W, Smith V, Davis S, Fessler S, McKinnon C, Katz M, Hammonds T, Jones NP, O'Connell J, Follows B, Mischke S, Caravella JA, Ioannidis S, Dinsmore C, Kim S, Behrens A, Komander D, Kessler BM, Urbé S, Clague MJ
The Journal of cell biology 2021 Mar 1;220(3)
The Journal of cell biology 2021 Mar 1;220(3)
SZB120 Exhibits Immunomodulatory Effects by Targeting eIF2α to Suppress Th17 Cell Differentiation.
Chen L, Bai J, Peng D, Gao Y, Cai X, Zhang J, Tang S, Niu L, Sun Y, Lou F, Zhou H, Yin Q, Wang Z, Sun L, Du X, Xu Z, Wang H, Li Q, Wang H
Journal of immunology (Baltimore, Md. : 1950) 2021 Mar 1;206(5):953-962
Journal of immunology (Baltimore, Md. : 1950) 2021 Mar 1;206(5):953-962
Melatonin inhibits vascular endothelial cell pyroptosis by improving mitochondrial function via up-regulation and demethylation of UQCRC1.
Zeng J, Tao J, Xia L, Zeng Z, Chen J, Wang Z, Meng J, Liu L
Biochemistry and cell biology = Biochimie et biologie cellulaire 2021 Jun;99(3):339-347
Biochemistry and cell biology = Biochimie et biologie cellulaire 2021 Jun;99(3):339-347
A novel peptide promotes human trophoblast proliferation and migration through PI3K/Akt/mTOR signaling pathway.
Ling L, Yuan X, Liu X, Pei W, Li R
Annals of translational medicine 2021 Jun;9(12):981
Annals of translational medicine 2021 Jun;9(12):981
Ninjinyoeito improves anxiety behavior in neuropeptide Y deficient zebrafish.
Kawabe M, Hayashi A, Komatsu M, Inui A, Shiozaki K
Neuropeptides 2021 Jun;87:102136
Neuropeptides 2021 Jun;87:102136
Interleukin-24 as a Pulmonary Target Cytokine in Bronchopulmonary Dysplasia.
Gao R, Li Z, Ai D, Ma J, Chen C, Liu X
Cell biochemistry and biophysics 2021 Jun;79(2):311-320
Cell biochemistry and biophysics 2021 Jun;79(2):311-320
Promoterless, Nuclease-Free Genome Editing Confers a Growth Advantage for Corrected Hepatocytes in Mice With Methylmalonic Acidemia.
Chandler RJ, Venturoni LE, Liao J, Hubbard BT, Schneller JL, Hoffmann V, Gordo S, Zang S, Ko CW, Chau N, Chiang K, Kay MA, Barzel A, Venditti CP
Hepatology (Baltimore, Md.) 2021 Jun;73(6):2223-2237
Hepatology (Baltimore, Md.) 2021 Jun;73(6):2223-2237
NCOA4-mediated ferritinophagy promoted inflammatory responses in periodontitis.
Guo W, Zhao Y, Li H, Lei L
Journal of periodontal research 2021 Jun;56(3):523-534
Journal of periodontal research 2021 Jun;56(3):523-534
Sodium sulfite causes gastric mucosal cell death by inducing oxidative stress.
Oshimo M, Nakashima F, Kai K, Matsui H, Shibata T, Akagawa M
Free radical research 2021 Jun;55(6):731-743
Free radical research 2021 Jun;55(6):731-743
Golgi phosphoprotein 3 promotes the proliferation of gallbladder carcinoma cells via regulation of the NLRP3 inflammasome.
Zhu Z, Zhu Q, Cai D, Chen L, Xie W, Bai Y, Luo K
Oncology reports 2021 Jun;45(6)
Oncology reports 2021 Jun;45(6)
FMR1/circCHAF1A/miR-211-5p/HOXC8 feedback loop regulates proliferation and tumorigenesis via MDM2-dependent p53 signaling in GSCs.
Jiang Y, Wang Z, Ying C, Hu J, Zeng T, Gao L
Oncogene 2021 Jun;40(24):4094-4110
Oncogene 2021 Jun;40(24):4094-4110
SMAR1 attenuates the stemness of osteosarcoma cells via through suppressing ABCG2 transcriptional activity.
Xu H, Liu T, Li W, Yao Q
Environmental toxicology 2021 Jun;36(6):1090-1098
Environmental toxicology 2021 Jun;36(6):1090-1098
Small Interfering RNA Targeting DMP1 Protects Mice Against Blood-Brain Barrier Disruption and Brain Injury After Intracerebral Hemorrhage.
Shu Y, Huang J, Gao M, Gan S, Zhu S, Xu S, Yang Z, Liao Y, Lu W
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2021 Jun;30(6):105760
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2021 Jun;30(6):105760
Cellular microRNAs influence replication of H3N2 canine influenza virus in infected cells.
Xie X, Pang M, Liang S, Lin Y, Zhao Y, Qiu D, Liu J, Dong Y, Liu Y
Veterinary microbiology 2021 Jun;257:109083
Veterinary microbiology 2021 Jun;257:109083
Sparstolonin B exerts beneficial effects on prostate cancer by acting on the reactive oxygen species-mediated PI3K/AKT pathway.
Liu S, Hu J, Shi C, Sun L, Yan W, Song Y
Journal of cellular and molecular medicine 2021 Jun;25(12):5511-5524
Journal of cellular and molecular medicine 2021 Jun;25(12):5511-5524
Fructose-1,6-bisphosphatase aggravates oxidative stress-induced apoptosis in asthma by suppressing the Nrf2 pathway.
Hu J, Wang J, Li C, Shang Y
Journal of cellular and molecular medicine 2021 Jun;25(11):5001-5014
Journal of cellular and molecular medicine 2021 Jun;25(11):5001-5014
Phgdh serves a protective role in Il‑1β induced chondrocyte inflammation and oxidative‑stress damage.
Huang H, Liu K, Ou H, Qian X, Wan J
Molecular medicine reports 2021 Jun;23(6)
Molecular medicine reports 2021 Jun;23(6)
Exploration of the hepatoprotective effect and mechanism of magnesium isoglycyrrhizinate in mice with arsenic trioxide‑induced acute liver injury.
Liu M, Zheng B, Liu P, Zhang J, Chu X, Dong C, Shi J, Liang Y, Chu L, Liu Y, Han X
Molecular medicine reports 2021 Jun;23(6)
Molecular medicine reports 2021 Jun;23(6)
Resveratrol sensitizes A549 cells to irradiation damage via suppression of store-operated calcium entry with Orai1 and STIM1 downregulation.
Lele W, Lei L, Liting Q
Experimental and therapeutic medicine 2021 Jun;21(6):587
Experimental and therapeutic medicine 2021 Jun;21(6):587
Differential expression of protein disulfide isomerase (PDI) in regulating endometrial receptivity in humans.
Fernando SR, Kottawatta KSA, Jiang L, Chen X, Cheng KW, Wong BP, Ng EH, Yeung WS, Lee KF
Reproductive biology 2021 Jun;21(2):100498
Reproductive biology 2021 Jun;21(2):100498
miR-29a-3p-dependent COL3A1 and COL5A1 expression reduction assists sulforaphane to inhibit gastric cancer progression.
Han S, Wang Z, Liu J, Wang HD, Yuan Q
Biochemical pharmacology 2021 Jun;188:114539
Biochemical pharmacology 2021 Jun;188:114539
RRx-001 ameliorates inflammatory diseases by acting as a potent covalent NLRP3 inhibitor.
Chen Y, He H, Lin B, Chen Y, Deng X, Jiang W, Zhou R
Cellular & molecular immunology 2021 Jun;18(6):1425-1436
Cellular & molecular immunology 2021 Jun;18(6):1425-1436
Signal-regulatory protein alpha is an anti-viral entry factor targeting viruses using endocytic pathways.
Sarute N, Cheng H, Yan Z, Salas-Briceno K, Richner J, Rong L, Ross SR
PLoS pathogens 2021 Jun;17(6):e1009662
PLoS pathogens 2021 Jun;17(6):e1009662
SNX-3 mediates retromer-independent tubular endosomal recycling by opposing EEA-1-facilitated trafficking.
Tian Y, Kang Q, Shi X, Wang Y, Zhang N, Ye H, Xu Q, Xu T, Zhang R
PLoS genetics 2021 Jun;17(6):e1009607
PLoS genetics 2021 Jun;17(6):e1009607
Paricalcitol inhibits oxidative stress-induced cell senescence of the bile duct epithelium dependent on modulating Sirt1 pathway in cholestatic mice.
Jia R, Yang F, Yan P, Ma L, Yang L, Li L
Free radical biology & medicine 2021 Jun;169:158-168
Free radical biology & medicine 2021 Jun;169:158-168
Natural molecule Munronoid I attenuates LPS-induced acute lung injury by promoting the K48-linked ubiquitination and degradation of TAK1.
Ma X, Li X, Di Q, Zhao X, Zhang R, Xiao Y, Sun P, Tang H, Quan J, Xiao W, Chen W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jun;138:111543
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jun;138:111543
Tumor cell membrane-based peptide delivery system targeting the tumor microenvironment for cancer immunotherapy and diagnosis.
Meng X, Wang J, Zhou J, Tian Q, Qie B, Zhou G, Duan W, Zhu Y
Acta biomaterialia 2021 Jun;127:266-275
Acta biomaterialia 2021 Jun;127:266-275
Long non-coding RNA muskelin 1 antisense RNA (MKLN1-AS) is a potential diagnostic and prognostic biomarker and therapeutic target for hepatocellular carcinoma.
Guo C, Zhou S, Yi W, Yang P, Li O, Liu J, Peng C
Experimental and molecular pathology 2021 Jun;120:104638
Experimental and molecular pathology 2021 Jun;120:104638
Upregulation of ZHX2 predicts poor prognosis and is correlated with immune infiltration in gastric cancer.
Cheng A, Guo X, Dai X, Wang Z
FEBS open bio 2021 Jun;11(6):1785-1798
FEBS open bio 2021 Jun;11(6):1785-1798
Effect of SOCS3 on apoptosis of human trophoblasts via adjustment of the JAK2/STAT3 signaling pathway in preterm birth.
Yin Y, Qu L, Zhu D, Wu Y, Zhou X
Translational pediatrics 2021 Jun;10(6):1637-1646
Translational pediatrics 2021 Jun;10(6):1637-1646
CDK5 positively regulates Notch1 signaling in pancreatic cancer cells by phosphorylation.
Chu Q, Wang L, Zhang J, Wang W, Wang Y
Cancer medicine 2021 Jun;10(11):3689-3699
Cancer medicine 2021 Jun;10(11):3689-3699
PBRM1 Cooperates with YTHDF2 to Control HIF-1α Protein Translation.
Shmakova A, Frost M, Batie M, Kenneth NS, Rocha S
Cells 2021 Jun 8;10(6)
Cells 2021 Jun 8;10(6)
Epac activation ameliorates tubulointerstitial inflammation in diabetic nephropathy.
Yang WX, Liu Y, Zhang SM, Wang HF, Liu YF, Liu JL, Li XH, Zeng MR, Han YZ, Liu FY, Sun L, Xiao L
Acta pharmacologica Sinica 2021 Jun 8;
Acta pharmacologica Sinica 2021 Jun 8;
Multilevel regulation of Wnt signaling by Zic2 in colon cancer due to mutation of β-catenin.
Xu Z, Zheng J, Chen Z, Guo J, Li X, Wang X, Qu C, Yuan L, Cheng C, Sun X, Yu J
Cell death & disease 2021 Jun 7;12(6):584
Cell death & disease 2021 Jun 7;12(6):584
The combination of CUDC-907 and gilteritinib shows promising in vitro and in vivo antileukemic activity against FLT3-ITD AML.
Qiao X, Ma J, Knight T, Su Y, Edwards H, Polin L, Li J, Kushner J, Dzinic SH, White K, Wang J, Lin H, Wang Y, Wang L, Wang G, Taub JW, Ge Y
Blood cancer journal 2021 Jun 7;11(6):111
Blood cancer journal 2021 Jun 7;11(6):111
Hypericin-mediated photodynamic therapy inhibits growth of colorectal cancer cells via inducing S phase cell cycle arrest and apoptosis.
Hu J, Song J, Tang Z, Wei S, Chen L, Zhou R
European journal of pharmacology 2021 Jun 5;900:174071
European journal of pharmacology 2021 Jun 5;900:174071
Cisplatin remodels the tumor immune microenvironment via the transcription factor EB in ovarian cancer.
Liu W, Wang Y, Xie Y, Dai T, Fan M, Li C, Zou Y
Cell death discovery 2021 Jun 5;7(1):136
Cell death discovery 2021 Jun 5;7(1):136
The benzoate plant metabolite ethyl gallate prevents cellular- and vascular-lipid accumulation in experimental models of atherosclerosis.
Liu W, Liu J, Xing S, Pan X, Wei S, Zhou M, Li Z, Wang L, Bielicki JK
Biochemical and biophysical research communications 2021 Jun 4;556:65-71
Biochemical and biophysical research communications 2021 Jun 4;556:65-71
Alisol A 24-acetate protects against brain microvascular endothelial cells injury through inhibiting miR-92a-3p/tight junctions axis.
Lu L, Lu T, Shen J, Lv X, Wei W, Wang H, Xue X
Aging 2021 Jun 4;13(11):15353-15365
Aging 2021 Jun 4;13(11):15353-15365
Lactobacillus acidophilus ATCC 4356 Exopolysaccharides Suppresses Mediators of Inflammation through the Inhibition of TLR2/STAT-3/P38-MAPK Pathway in DEN-Induced Hepatocarcinogenesis in Rats.
Khedr OMS, El-Sonbaty SM, Moawed FSM, Kandil EI, Abdel-Maksoud BE
Nutrition and cancer 2021 Jun 4;:1-11
Nutrition and cancer 2021 Jun 4;:1-11
Formin-like protein 2 promotes cell proliferation by a p27-related mechanism in human breast cancer cells.
Jiao X, Wang B, Feng C, Song S, Tian B, Zhou C, Gao X, Sun W, Liu P
BMC cancer 2021 Jun 30;21(1):760
BMC cancer 2021 Jun 30;21(1):760
Purification, characterization and anti-atherosclerotic effects of the polysaccharides from the fruiting body of Cordyceps militaris.
Yang X, Lin P, Wang J, Liu N, Yin F, Shen N, Guo S
International journal of biological macromolecules 2021 Jun 30;181:890-904
International journal of biological macromolecules 2021 Jun 30;181:890-904
Self-stabilizing regulation of deubiquitinating enzymes in an enzymatic activity-dependent manner.
Hou Z, Shi W, Feng J, Wang W, Zheng E, Lin H, Yu C, Li L
International journal of biological macromolecules 2021 Jun 30;181:1081-1091
International journal of biological macromolecules 2021 Jun 30;181:1081-1091
Breast tumor stiffness instructs bone metastasis via maintenance of mechanical conditioning.
Watson AW, Grant AD, Parker SS, Hill S, Whalen MB, Chakrabarti J, Harman MW, Roman MR, Forte BL, Gowan CC, Castro-Portuguez R, Stolze LK, Franck C, Cusanovich DA, Zavros Y, Padi M, Romanoski CE, Mouneimne G
Cell reports 2021 Jun 29;35(13):109293
Cell reports 2021 Jun 29;35(13):109293
Neu1 deficiency induces abnormal emotional behavior in zebrafish.
Ikeda A, Komamizu M, Hayashi A, Yamasaki C, Okada K, Kawabe M, Komatsu M, Shiozaki K
Scientific reports 2021 Jun 29;11(1):13477
Scientific reports 2021 Jun 29;11(1):13477
Thymosin β4 reverses phenotypic polarization of glial cells and cognitive impairment via negative regulation of NF-κB signaling axis in APP/PS1 mice.
Wang M, Feng LR, Li ZL, Ma KG, Chang KW, Chen XL, Yang PB, Ji SF, Ma YB, Han H, Ruganzua JB, Yang WN, Qian YH
Journal of neuroinflammation 2021 Jun 28;18(1):146
Journal of neuroinflammation 2021 Jun 28;18(1):146
The Anti-Tumor Effect and Underlying Apoptotic Mechanism of Ginsenoside Rk1 and Rg5 in Human Liver Cancer Cells.
Chen C, Lv Q, Li Y, Jin YH
Molecules (Basel, Switzerland) 2021 Jun 27;26(13)
Molecules (Basel, Switzerland) 2021 Jun 27;26(13)
DUSP1 overexpression attenuates renal tubular mitochondrial dysfunction by restoring Parkin-mediated mitophagy in diabetic nephropathy.
Lu C, Wu B, Liao Z, Xue M, Zou Z, Feng J, Sheng J
Biochemical and biophysical research communications 2021 Jun 25;559:141-147
Biochemical and biophysical research communications 2021 Jun 25;559:141-147
LncRNA CARMN overexpression promotes prognosis and chemosensitivity of triple negative breast cancer via acting as miR143-3p host gene and inhibiting DNA replication.
Sheng X, Dai H, Du Y, Peng J, Sha R, Yang F, Zhou L, Lin Y, Xu S, Wu Y, Yin W, Lu J
Journal of experimental & clinical cancer research : CR 2021 Jun 23;40(1):205
Journal of experimental & clinical cancer research : CR 2021 Jun 23;40(1):205
Binding of Benzo[a]pyrene Alters the Bioreactivity of Fine Biochar Particles toward Macrophages Leading to Deregulated Macrophagic Defense and Autophagy.
Ma J, Liu X, Yang Y, Qiu J, Dong Z, Ren Q, Zuo YY, Xia T, Chen W, Liu S
ACS nano 2021 Jun 22;15(6):9717-9731
ACS nano 2021 Jun 22;15(6):9717-9731
LINC00842 inactivates transcription co-regulator PGC-1α to promote pancreatic cancer malignancy through metabolic remodelling.
Huang X, Pan L, Zuo Z, Li M, Zeng L, Li R, Ye Y, Zhang J, Wu G, Bai R, Zhuang L, Wei L, Zheng Y, Su J, Deng J, Deng S, Zhang S, Zhu S, Che X, Wang C, Wu C, Chen R, Lin D, Zheng J
Nature communications 2021 Jun 22;12(1):3830
Nature communications 2021 Jun 22;12(1):3830
LINC_00355 promotes gastric cancer progression by upregulating PHF19 expression through sponging miR-15a-5p.
Zhang J, Lv W, Liu Y, Fu W, Chen B, Ma Q, Gao X
BMC cancer 2021 Jun 2;21(1):657
BMC cancer 2021 Jun 2;21(1):657
Colorectal cancer cells utilize autophagy to maintain mitochondrial metabolism for cell proliferation under nutrient stress.
Devenport SN, Singhal R, Radyk MD, Taranto JG, Kerk SA, Chen B, Goyert JW, Jain C, Das NK, Oravecz-Wilson K, Zhang L, Greenson JK, Chen YE, Soleimanpour SA, Reddy P, Lyssiotis CA, Shah YM
JCI insight 2021 Jun 17;6(14)
JCI insight 2021 Jun 17;6(14)
Isorhamnetin Promotes Estrogen Biosynthesis and Proliferation in Porcine Granulosa Cells via the PI3K/Akt Signaling Pathway.
Li X, Chen H, Zhang Z, Xu D, Duan J, Li X, Yang L, Hua R, Cheng J, Li Q
Journal of agricultural and food chemistry 2021 Jun 16;69(23):6535-6542
Journal of agricultural and food chemistry 2021 Jun 16;69(23):6535-6542
Protective effect of scorpion venom heat-resistant synthetic peptide against PM2.5-induced microglial polarization via TLR4-mediated autophagy activating PI3K/AKT/NF-κB signaling pathway.
Xu X, Xu H, Ren F, Huang L, Xu J, Li F
Journal of neuroimmunology 2021 Jun 15;355:577567
Journal of neuroimmunology 2021 Jun 15;355:577567
HIF-2α activation potentiates oxidative cell death in colorectal cancers by increasing cellular iron.
Singhal R, Mitta SR, Das NK, Kerk SA, Sajjakulnukit P, Solanki S, Andren A, Kumar R, Olive KP, Banerjee R, Lyssiotis CA, Shah YM
The Journal of clinical investigation 2021 Jun 15;131(12)
The Journal of clinical investigation 2021 Jun 15;131(12)
Aerobic Exercise Improves Mitochondrial Function in Sarcopenia Mice Through Sestrin2 in an AMPKα2-Dependent Manner.
Liu S, Yu C, Xie L, Niu Y, Fu L
The journals of gerontology. Series A, Biological sciences and medical sciences 2021 Jun 14;76(7):1161-1168
The journals of gerontology. Series A, Biological sciences and medical sciences 2021 Jun 14;76(7):1161-1168
The engineered expression of secreted HSPB5-Fc in CHO cells exhibits cytoprotection in vitro.
Li J, Yu J, Xue W, Huang H, Yan L, Sang F, An S, Zhang J, Wang M, Zhang J, Li H, Cui X, He J, Hu Y
BMC biotechnology 2021 Jun 14;21(1):39
BMC biotechnology 2021 Jun 14;21(1):39
Protective effects of 4-octyl itaconate against inflammatory response in angiotensin II-induced oxidative stress in human primary retinal pigment epithelium.
Fu X, Wu M, Zhou X
Biochemical and biophysical research communications 2021 Jun 11;557:77-84
Biochemical and biophysical research communications 2021 Jun 11;557:77-84
Protective Effects of Bone Marrow Mesenchymal Stem Cells (BMMSCS) Combined with Normothermic Machine Perfusion on Liver Grafts Donated After Circulatory Death via Reducing the Ferroptosis of Hepatocytes.
Sun D, Yang L, Zheng W, Cao H, Wu L, Song H
Medical science monitor : international medical journal of experimental and clinical research 2021 Jun 11;27:e930258
Medical science monitor : international medical journal of experimental and clinical research 2021 Jun 11;27:e930258
Central nervous system-targeted adeno-associated virus gene therapy in methylmalonic acidemia.
May FJ, Head PE, Venturoni LE, Chandler RJ, Venditti CP
Molecular therapy. Methods & clinical development 2021 Jun 11;21:765-776
Molecular therapy. Methods & clinical development 2021 Jun 11;21:765-776
CSNK2A1-mediated phosphorylation of HMGA2 modulates cisplatin resistance in cervical cancer.
Shi Z, Wu D, Xu H, Yang J, Sun X
FEBS open bio 2021 Jun 11;
FEBS open bio 2021 Jun 11;
LncRNA CTD-2528L19.6 prevents the progression of IPF by alleviating fibroblast activation.
Chen T, Guo Y, Wang J, Ai L, Ma L, He W, Li Z, Yu X, Li J, Fan X, Gu Y, Liang H
Cell death & disease 2021 Jun 10;12(6):600
Cell death & disease 2021 Jun 10;12(6):600
Resveratrol and its derivative pterostilbene ameliorate intestine injury in intrauterine growth-retarded weanling piglets by modulating redox status and gut microbiota.
Chen Y, Zhang H, Chen Y, Jia P, Ji S, Zhang Y, Wang T
Journal of animal science and biotechnology 2021 Jun 10;12(1):70
Journal of animal science and biotechnology 2021 Jun 10;12(1):70
A comparison expression analysis of CXCR4, CXCL9 and Caspase-9 in dermal vascular endothelial cells between keloids and normal skin on chemotaxis and apoptosis.
Dong X, Zhang M, Chen Y, Li C, Wang Y, Jin X
Journal of plastic surgery and hand surgery 2021 Jun 10;:1-10
Journal of plastic surgery and hand surgery 2021 Jun 10;:1-10
Tumors exploit FTO-mediated regulation of glycolytic metabolism to evade immune surveillance.
Liu Y, Liang G, Xu H, Dong W, Dong Z, Qiu Z, Zhang Z, Li F, Huang Y, Li Y, Wu J, Yin S, Zhang Y, Guo P, Liu J, Xi JJ, Jiang P, Han D, Yang CG, Xu MM
Cell metabolism 2021 Jun 1;33(6):1221-1233.e11
Cell metabolism 2021 Jun 1;33(6):1221-1233.e11
Galectin-9 Targets NLRP3 for Autophagic Degradation to Limit Inflammation.
Wang W, Qin Y, Song H, Wang L, Jia M, Zhao C, Gong M, Zhao W
Journal of immunology (Baltimore, Md. : 1950) 2021 Jun 1;206(11):2692-2699
Journal of immunology (Baltimore, Md. : 1950) 2021 Jun 1;206(11):2692-2699
Butyrate enhances CPT1A activity to promote fatty acid oxidation and iTreg differentiation.
Hao F, Tian M, Zhang X, Jin X, Jiang Y, Sun X, Wang Y, Peng P, Liu J, Xia C, Feng Y, Wei M
Proceedings of the National Academy of Sciences of the United States of America 2021 Jun 1;118(22)
Proceedings of the National Academy of Sciences of the United States of America 2021 Jun 1;118(22)
25-Hydroxycholesterol mitigates hepatic ischemia reperfusion injury via mediating mitophagy.
Cao Q, Luo J, Xiong Y, Liu Z, Ye Q
International immunopharmacology 2021 Jul;96:107643
International immunopharmacology 2021 Jul;96:107643
Targeting TSP-1 decreased periodontitis by attenuating extracellular matrix degradation and alveolar bone destruction.
Liu X, Jin J, Liu Y, Shen Z, Zhao R, Ou L, Xing T
International immunopharmacology 2021 Jul;96:107618
International immunopharmacology 2021 Jul;96:107618
Pirfenidone mediates cigarette smoke extract induced inflammation and oxidative stress in vitro and in vivo.
Ma Y, Luo L, Liu X, Li H, Zeng Z, He X, Zhan Z, Chen Y
International immunopharmacology 2021 Jul;96:107593
International immunopharmacology 2021 Jul;96:107593
A neutral polysaccharide from Ophiocordyceps lanpingensis restrains cisplatin-induced nephrotoxicity.
Zhou S, Zhou Y, Yu J, Jiang L, Xiang Y, Wang J, Du Y, Cui X, Ge F
Food science & nutrition 2021 Jul;9(7):3602-3616
Food science & nutrition 2021 Jul;9(7):3602-3616
YAP/TEAD4-induced KIF4A contributes to the progression and worse prognosis of esophageal squamous cell carcinoma.
Li Y, Zhu X, Yang M, Wang Y, Li J, Fang J, Guo W, Ma S, Guan F
Molecular carcinogenesis 2021 Jul;60(7):440-454
Molecular carcinogenesis 2021 Jul;60(7):440-454
Thioredoxin-1 Rescues MPP+/MPTP-Induced Ferroptosis by Increasing Glutathione Peroxidase 4.
Bai L, Yan F, Deng R, Gu R, Zhang X, Bai J
Molecular neurobiology 2021 Jul;58(7):3187-3197
Molecular neurobiology 2021 Jul;58(7):3187-3197
miR-671-5p Attenuates Neuroinflammation via Suppressing NF-κB Expression in an Acute Ischemic Stroke Model.
Deng L, Guo Y, Liu J, Wang X, Chen S, Wang Q, Rao J, Wang Y, Zuo T, Hu Q, Zhao X, Dong Z
Neurochemical research 2021 Jul;46(7):1801-1813
Neurochemical research 2021 Jul;46(7):1801-1813
DHCR24 Knockdown Lead to Hyperphosphorylation of Tau at Thr181, Thr231, Ser262, Ser396, and Ser422 Sites by Membrane Lipid-Raft Dependent PP2A Signaling in SH-SY5Y Cells.
Qi Z, Zhang Y, Yao K, Zhang M, Xu Y, Zhang J, Bai X, Zu H
Neurochemical research 2021 Jul;46(7):1627-1640
Neurochemical research 2021 Jul;46(7):1627-1640
Hawthorn polyphenols, D-chiro-inositol, and epigallocatechin gallate exert a synergistic hypoglycemic effect.
Xin C, Zhao M, Wang J, Wang Z
Journal of food biochemistry 2021 Jul;45(7):e13771
Journal of food biochemistry 2021 Jul;45(7):e13771
EZH2 regulates expression of FOXC1 by mediating H3K27me3 in breast cancers.
Zheng XJ, Li W, Yi J, Liu JY, Ren LW, Zhu XM, Liu SW, Wang JH, Du GH
Acta pharmacologica Sinica 2021 Jul;42(7):1171-1179
Acta pharmacologica Sinica 2021 Jul;42(7):1171-1179
The role of the HIF-1α/ALYREF/PKM2 axis in glycolysis and tumorigenesis of bladder cancer.
Wang JZ, Zhu W, Han J, Yang X, Zhou R, Lu HC, Yu H, Yuan WB, Li PC, Tao J, Lu Q, Wei JF, Yang H
Cancer communications (London, England) 2021 Jul;41(7):560-575
Cancer communications (London, England) 2021 Jul;41(7):560-575
Sestrin2 protects against traumatic brain injury by reinforcing the activation of Nrf2 signaling.
Liu X, Li M, Zhu J, Huang W, Song J
Human & experimental toxicology 2021 Jul;40(7):1095-1111
Human & experimental toxicology 2021 Jul;40(7):1095-1111
Targeted radioimmunotherapy with the iodine-131-labeled caerin 1.1 peptide for human anaplastic thyroid cancer in nude mice.
Lin R, Ma B, Liu N, Zhang L, He T, Liu X, Chen T, Liu W, Liang Y, Wang T, Ni G, Liu X, Yang N, Zhang J, Yuan J
Annals of nuclear medicine 2021 Jul;35(7):811-822
Annals of nuclear medicine 2021 Jul;35(7):811-822
Hepcidin sequesters iron to sustain nucleotide metabolism and mitochondrial function in colorectal cancer epithelial cells.
Schwartz AJ, Goyert JW, Solanki S, Kerk SA, Chen B, Castillo C, Hsu PP, Do BT, Singhal R, Dame MK, Lee HJ, Spence JR, Lakhal-Littleton S, Heiden MGV, Lyssiotis CA, Xue X, Shah YM
Nature metabolism 2021 Jul;3(7):969-982
Nature metabolism 2021 Jul;3(7):969-982
TCDD induced lipid accumulation by impairment of autophagic flux in THP-1 macrophages.
Lu J, Liu M, Fan Y, Zheng H, Guan S
Environmental science and pollution research international 2021 Jul;28(27):36053-36059
Environmental science and pollution research international 2021 Jul;28(27):36053-36059
TLR2 senses the SARS-CoV-2 envelope protein to produce inflammatory cytokines.
Zheng M, Karki R, Williams EP, Yang D, Fitzpatrick E, Vogel P, Jonsson CB, Kanneganti TD
Nature immunology 2021 Jul;22(7):829-838
Nature immunology 2021 Jul;22(7):829-838
Effect of the interference with DRP1 expression on the biological characteristics of glioma stem cells.
Zhang L, Cao H, Tao H, Yang J, Gong W, Hu Q
Experimental and therapeutic medicine 2021 Jul;22(1):696
Experimental and therapeutic medicine 2021 Jul;22(1):696
A conserved ubiquitin- and ESCRT-dependent pathway internalizes human lysosomal membrane proteins for degradation.
Zhang W, Yang X, Chen L, Liu YY, Venkatarangan V, Reist L, Hanson P, Xu H, Wang Y, Li M
PLoS biology 2021 Jul;19(7):e3001361
PLoS biology 2021 Jul;19(7):e3001361
C1orf61 promotes hepatocellular carcinoma metastasis and increases the therapeutic response to sorafenib.
Yu Y, Wang Z, Huang Z, Tang X, Huang X, Li W
Biochimica et biophysica acta. Molecular cell research 2021 Jul;1868(8):119048
Biochimica et biophysica acta. Molecular cell research 2021 Jul;1868(8):119048
Visfatin regulates Pg LPS-induced proinflammatory/prodegradative effects in healthy and inflammatory periodontal cells partially via NF-κB pathway.
Yao S, Jiang C, Zhang H, Gao X, Guo Y, Cao Z
Biochimica et biophysica acta. Molecular cell research 2021 Jul;1868(8):119042
Biochimica et biophysica acta. Molecular cell research 2021 Jul;1868(8):119042
Ets-2 deletion in myeloid cells attenuates IL-1α-mediated inflammatory disease caused by a Ptpn6 point mutation.
Tartey S, Gurung P, Karki R, Burton A, Hertzog P, Kanneganti TD
Cellular & molecular immunology 2021 Jul;18(7):1798-1808
Cellular & molecular immunology 2021 Jul;18(7):1798-1808
DENV NS1 and MMP-9 cooperate to induce vascular leakage by altering endothelial cell adhesion and tight junction.
Pan P, Li G, Shen M, Yu Z, Ge W, Lao Z, Fan Y, Chen K, Ding Z, Wang W, Wan P, Shereen MA, Luo Z, Chen X, Zhang Q, Lin L, Wu J
PLoS pathogens 2021 Jul;17(7):e1008603
PLoS pathogens 2021 Jul;17(7):e1008603
Chemical conjugation of FITC to track silica nanoparticles in vivo and in vitro: An emerging method to assess the reproductive toxicity of industrial nanomaterials.
Li J, Tian J, Yin H, Peng Y, Liu S, Yao S, Zhang L
Environment international 2021 Jul;152:106497
Environment international 2021 Jul;152:106497
Andrographolide Attenuates Gut-Brain-Axis Associated Pathology in Gulf War Illness by Modulating Bacteriome-Virome Associated Inflammation and Microglia-Neuron Proinflammatory Crosstalk.
Saha P, Skidmore PT, Holland LA, Mondal A, Bose D, Seth RK, Sullivan K, Janulewicz PA, Horner R, Klimas N, Nagarkatti M, Nagarkatti P, Lim ES, Chatterjee S
Brain sciences 2021 Jul 9;11(7)
Brain sciences 2021 Jul 9;11(7)
ets1 associates with KMT5A to participate in high glucose-mediated EndMT via upregulation of PFN2 expression in diabetic nephropathy.
Lu L, Zhong Z, Gu J, Nan K, Zhu M, Miao C
Molecular medicine (Cambridge, Mass.) 2021 Jul 8;27(1):74
Molecular medicine (Cambridge, Mass.) 2021 Jul 8;27(1):74
Inhibition of xCT suppresses the efficacy of anti-PD-1/L1 melanoma treatment through exosomal PD-L1-induced macrophage M2 polarization.
Liu N, Zhang J, Yin M, Liu H, Zhang X, Li J, Yan B, Guo Y, Zhou J, Tao J, Hu S, Chen X, Peng C
Molecular therapy : the journal of the American Society of Gene Therapy 2021 Jul 7;29(7):2321-2334
Molecular therapy : the journal of the American Society of Gene Therapy 2021 Jul 7;29(7):2321-2334
Baicalein Delays H2O2-Induced Astrocytic Senescence through Inhibition of Senescence-Associated Secretory Phenotype (SASP), Suppression of JAK2/STAT1/NF-κB Pathway, and Regulation of Leucine Metabolism.
Gao L, Zheng WG, Wu XK, Du GH, Qin XM
ACS chemical neuroscience 2021 Jul 7;12(13):2320-2335
ACS chemical neuroscience 2021 Jul 7;12(13):2320-2335
Piperlongumine inhibits migration and proliferation of castration-resistant prostate cancer cells via triggering persistent DNA damage.
Zhang DF, Yang ZC, Chen JQ, Jin XX, Qiu YD, Chen XJ, Shi HY, Liu ZG, Wang MS, Liang G, Zheng XH
BMC complementary medicine and therapies 2021 Jul 6;21(1):195
BMC complementary medicine and therapies 2021 Jul 6;21(1):195
Baicalein inhibits RLS3-induced ferroptosis in melanocytes.
Yang M, Li X, Li H, Zhang X, Liu X, Song Y
Biochemical and biophysical research communications 2021 Jul 5;561:65-72
Biochemical and biophysical research communications 2021 Jul 5;561:65-72
Melatonin alleviates Ochratoxin A-induced liver inflammation involved intestinal microbiota homeostasis and microbiota-independent manner.
Xia D, Yang L, Li Y, Chen J, Zhang X, Wang H, Zhai S, Jiang X, Meca G, Wang S, Huang L, Zhu S, Fu Y, Ma W, Zhu Y, Ye H, Wang W
Journal of hazardous materials 2021 Jul 5;413:125239
Journal of hazardous materials 2021 Jul 5;413:125239
mPEG2k-PCLx Polymeric Micelles Influence Pharmacokinetics and Hypoglycemic Efficacy of Metformin through Inhibition of Organic Cation Transporters in Rats.
Zhang Y, Sun M, Jian S, Huang J, Xiao C, Zhang X, Hu R, Si L
Molecular pharmaceutics 2021 Jul 5;18(7):2586-2599
Molecular pharmaceutics 2021 Jul 5;18(7):2586-2599
The intrinsic role and mechanism of tumor expressed-CD38 on lung adenocarcinoma progression.
Gao L, Liu Y, Du X, Ma S, Ge M, Tang H, Han C, Zhao X, Liu Y, Shao Y, Wu Z, Zhang L, Meng F, Xiao-Feng Qin F
Cell death & disease 2021 Jul 5;12(7):680
Cell death & disease 2021 Jul 5;12(7):680
Probiotic-fermented black tartary buckwheat alleviates hyperlipidemia and gut microbiota dysbiosis in rats fed with a high-fat diet.
Ren Y, Wu S, Xia Y, Huang J, Ye J, Xuan Z, Li P, Du B
Food & function 2021 Jul 5;12(13):6045-6057
Food & function 2021 Jul 5;12(13):6045-6057
L-Theanine regulates glutamine metabolism and immune function by binding to cannabinoid receptor 1.
Liu A, Lin L, Xu W, Gong Z, Liu Z, Xiao W
Food & function 2021 Jul 5;12(13):5755-5769
Food & function 2021 Jul 5;12(13):5755-5769
NR1D1 suppressed the growth of ovarian cancer by abrogating the JAK/STAT3 signaling pathway.
Wang H, Fu Y
BMC cancer 2021 Jul 30;21(1):871
BMC cancer 2021 Jul 30;21(1):871
Glycoursodeoxycholic acid ameliorates diet-induced metabolic disorders with inhibiting endoplasmic reticulum stress.
Cheng L, Chen T, Guo M, Liu P, Qiao X, Wei Y, She J, Li B, Xi W, Zhou J, Yuan Z, Wu Y, Liu J
Clinical science (London, England : 1979) 2021 Jul 30;135(14):1689-1706
Clinical science (London, England : 1979) 2021 Jul 30;135(14):1689-1706
Subregion-Specific Regulation of Dopamine D1 Receptor Signaling in the Striatum: Implication for L-DOPA-Induced Dyskinesia.
Sugiyama K, Kuroiwa M, Shuto T, Ohnishi YN, Kawahara Y, Miyamoto Y, Fukuda T, Nishi A
The Journal of neuroscience : the official journal of the Society for Neuroscience 2021 Jul 28;41(30):6388-6414
The Journal of neuroscience : the official journal of the Society for Neuroscience 2021 Jul 28;41(30):6388-6414
Growth Hormone Receptor (GHR) 6Ω Pseudoexon Activation: a Novel Cause of Severe Growth Hormone Insensitivity.
Cottrell E, Maharaj A, Williams J, Chatterjee S, Cirillo G, Miraglia Del Giudice E, Festa A, Palumbo S, Capalbo D, Salerno M, Pignata C, Savage MO, Schilbach K, Bidlingmaier M, Hwa V, Metherell LA, Grandone A, Storr HL
The Journal of clinical endocrinology and metabolism 2021 Jul 28;
The Journal of clinical endocrinology and metabolism 2021 Jul 28;
HELLS serves as a poor prognostic biomarker and its downregulation reserves the malignant phenotype in pancreatic cancer.
Wang FJ, Jing YH, Cheng CS, Cao ZQ, Jiao JY, Chen Z
BMC medical genomics 2021 Jul 27;14(1):189
BMC medical genomics 2021 Jul 27;14(1):189
Serum exosomes from young rats improve the reduced osteogenic differentiation of BMSCs in aged rats with osteoporosis after fatigue loading in vivo.
Xun J, Li C, Liu M, Mei Y, Zhou Q, Wu B, Xie F, Liu Y, Dai R
Stem cell research & therapy 2021 Jul 27;12(1):424
Stem cell research & therapy 2021 Jul 27;12(1):424
Integrated analysis of m6A mRNA methylation in rats with monocrotaline-induced pulmonary arterial hypertension.
Zeng Y, Huang T, Zuo W, Wang D, Xie Y, Wang X, Xiao Z, Chen Z, Liu Q, Liu N, Xiao Y
Aging 2021 Jul 26;13(14):18238-18256
Aging 2021 Jul 26;13(14):18238-18256
Effects of Loblolly Pine Biochar and Wood Vinegar on Poultry Litter Nutrients and Microbial Abundance.
Mohammadi-Aragh MK, Stokes CE, Street JT, Linhoss JE
Animals : an open access journal from MDPI 2021 Jul 26;11(8)
Animals : an open access journal from MDPI 2021 Jul 26;11(8)
REM Sleep Deprivation Impairs Learning and Memory by Decreasing Brain O-GlcNAc Cycling in Mouse.
Kim SM, Zhang S, Park J, Sung HJ, Tran TT, Chung C, Han IO
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2021 Jul 26;
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2021 Jul 26;
Phenethylamine in chlorella alleviates high-fat diet-induced mouse liver damage by regulating generation of methylglyoxal.
Zheng Y, Martin-Morales A, Wang J, Fujishima M, Okumura E, Sato K
NPJ science of food 2021 Jul 23;5(1):22
NPJ science of food 2021 Jul 23;5(1):22
Hypoxic preconditioning rejuvenates mesenchymal stem cells and enhances neuroprotection following intracerebral hemorrhage via the miR-326-mediated autophagy.
Liu J, He J, Ge L, Xiao H, Huang Y, Zeng L, Jiang Z, Lu M, Hu Z
Stem cell research & therapy 2021 Jul 22;12(1):413
Stem cell research & therapy 2021 Jul 22;12(1):413
VALD-3, a Schiff base ligand synthesized from o-vanillin derivatives, induces cell cycle arrest and apoptosis in breast cancer cells by inhibiting the Wnt/β-catenin pathway.
Li H, Dang C, Tai X, Xue L, Meng Y, Ma S, Zhang J
Scientific reports 2021 Jul 22;11(1):14985
Scientific reports 2021 Jul 22;11(1):14985
Lactate secreted by PKM2 upregulation promotes Galectin-9-mediated immunosuppression via inhibiting NF-κB pathway in HNSCC.
Chang H, Xu Q, Li J, Li M, Zhang Z, Ma H, Yang X
Cell death & disease 2021 Jul 21;12(8):725
Cell death & disease 2021 Jul 21;12(8):725
Expression and significance of let-7a and tumor necrosis factor-alpha in placenta of severe preeclampsia.
Zhou T, Wang W, Qi T, Ma S, Lu W
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2021 Jul 21;:1-5
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2021 Jul 21;:1-5
Spodoptera frugiperda mRNA export factor interacts with and mediates the nuclear import of Autographa californica multiple nucleopolyhedrovirus ORF34 (Ac34).
Tang Z, Luo W, Huang Z, Yuan M, Wu W, Yang K
Virus research 2021 Jul 2;299:198438
Virus research 2021 Jul 2;299:198438
Establishment of a specific in vivo Cu(Ⅰ) reporting system based on metallothionein screening.
Ma M, Qiu B, Jin J, Wang J, Nie Y, Liang Y, Yu Z, Teng CB
Metallomics : integrated biometal science 2021 Jul 2;13(7)
Metallomics : integrated biometal science 2021 Jul 2;13(7)
The critical role of B4GALT4 in promoting microtubule spindle assembly in HCC through the regulation of PLK1 and RHAMM expression.
Dai Z, Wang K, Gao Y
Journal of cellular physiology 2021 Jul 16;
Journal of cellular physiology 2021 Jul 16;
Potential effect of EGCG on the anti-tumor efficacy of metformin in melanoma cells.
Xu A, Lee J, Zhao Y, Wang Y, Li X, Xu P
Journal of Zhejiang University. Science. B 2021 Jul 15;22(7):548-562
Journal of Zhejiang University. Science. B 2021 Jul 15;22(7):548-562
Decreased expression of the clock gene Bmal1 is involved in the pathogenesis of temporal lobe epilepsy.
Wu H, Liu Y, Liu L, Meng Q, Du C, Li K, Dong S, Zhang Y, Li H, Zhang H
Molecular brain 2021 Jul 14;14(1):113
Molecular brain 2021 Jul 14;14(1):113
p53 deficiency induces MTHFD2 transcription to promote cell proliferation and restrain DNA damage.
Li G, Wu J, Li L, Jiang P
Proceedings of the National Academy of Sciences of the United States of America 2021 Jul 13;118(28)
Proceedings of the National Academy of Sciences of the United States of America 2021 Jul 13;118(28)
Cyclophilin A Inhibits Human Respiratory Syncytial Virus (RSV) Replication by Binding to RSV-N through Its PPIase Activity.
Liang W, Zhang Y, Li M, Al-Shaebi F, Li J, Zhang J, Wei L
Journal of virology 2021 Jul 12;95(15):e0056321
Journal of virology 2021 Jul 12;95(15):e0056321
Stimuli-Responsive and Highly Penetrable Nanoparticles as a Multifunctional Nanoplatform for Boosting Nonsmall Cell Lung Cancer siRNA Therapy.
Shi M, Wang Y, Zhao X, Zhang J, Hu H, Qiao M, Zhao X, Chen D
ACS biomaterials science & engineering 2021 Jul 12;7(7):3141-3155
ACS biomaterials science & engineering 2021 Jul 12;7(7):3141-3155
Activation of Adenosine A1 Receptor in Ischemic Stroke: Neuroprotection by Tetrahydroxy Stilbene Glycoside as an Agonist.
Ruan L, Li G, Zhao W, Meng H, Zheng Q, Wang J
Antioxidants (Basel, Switzerland) 2021 Jul 12;10(7)
Antioxidants (Basel, Switzerland) 2021 Jul 12;10(7)
The ZMYND8-regulated mevalonate pathway endows YAP-high intestinal cancer with metabolic vulnerability.
Pan Q, Zhong S, Wang H, Wang X, Li N, Li Y, Zhang G, Yuan H, Lian Y, Chen Q, Han Y, Guo J, Liu Q, Qiu T, Jiang J, Li Q, Tan M, Yin H, Peng J, Xiao Y, Qin J
Molecular cell 2021 Jul 1;81(13):2736-2751.e8
Molecular cell 2021 Jul 1;81(13):2736-2751.e8
Evaluating the protective effects of individual or combined ginsenoside compound K and the downregulation of soluble epoxide hydrolase expression against sodium valproate-induced liver cell damage.
Zhou L, Zeng X, Rao T, Tan Z, Zhou G, Ouyang D, Chen L
Toxicology and applied pharmacology 2021 Jul 1;422:115555
Toxicology and applied pharmacology 2021 Jul 1;422:115555
MicroRNA-363-3p promotes apoptosis in response to cadmium-induced renal injury by down-regulating phosphoinositide 3-kinase expression.
Chen J, Lai W, Deng Y, Liu M, Dong M, Liu Z, Wang T, Li X, Zhao Z, Yin X, Yang J, Yu R, Liu L
Toxicology letters 2021 Jul 1;345:12-23
Toxicology letters 2021 Jul 1;345:12-23
p55PIK deficiency and its NH2-terminal derivative inhibit inflammation and emphysema in COPD mouse model.
Wang T, Du X, Wang Z, Gu Y, Huang Q, Wu J, Zhan Y, Chen J, Xiao C, Xie J
American journal of physiology. Lung cellular and molecular physiology 2021 Jul 1;321(1):L159-L173
American journal of physiology. Lung cellular and molecular physiology 2021 Jul 1;321(1):L159-L173
Novel functional variants in the Notch pathway and survival of Chinese colorectal cancer.
Qu X, Zhao L, Wang M, Zhang R, Cheng L, Qiu L, Tong X, Cai S, Wei Q, Li Q
International journal of cancer 2021 Jul 1;149(1):84-96
International journal of cancer 2021 Jul 1;149(1):84-96
Alterations of GABA B receptors in the APP/PS1 mouse model of Alzheimer's disease.
Salazar AM, Leisgang AM, Ortiz AA, Murtishaw AS, Kinney JW
Neurobiology of aging 2021 Jan;97:129-143
Neurobiology of aging 2021 Jan;97:129-143
Identification and validation of L Antigen Family Member 3 as an immune-related biomarker associated with the progression of papillary thyroid cancer.
Dong X, Yang Q, Gu J, Lv S, Song D, Chen D, Song J, Zhang X, Huang D
International immunopharmacology 2021 Jan;90:107267
International immunopharmacology 2021 Jan;90:107267
Postnatal overfeeding induces hepatic microRNA-221 expression and impairs the PI3K/AKT pathway in adult male rats.
Huang F, Zhu P, Wang J, Chen J, Lin W
Pediatric research 2021 Jan;89(1):143-149
Pediatric research 2021 Jan;89(1):143-149
Uncaria rhynchophylla ameliorates unpredictable chronic mild stress-induced depression in mice via activating 5-HT1A receptor: Insights from transcriptomics.
Qiao YL, Zhou JJ, Liang JH, Deng XP, Zhang ZJ, Huang HL, Li S, Dai SF, Liu CQ, Luan ZL, Yu ZL, Sun CP, Ma XC
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Jan;81:153436
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Jan;81:153436
Regulation of branched-chain amino acid metabolism by hypoxia-inducible factor in glioblastoma.
Zhang B, Chen Y, Shi X, Zhou M, Bao L, Hatanpaa KJ, Patel T, DeBerardinis RJ, Wang Y, Luo W
Cellular and molecular life sciences : CMLS 2021 Jan;78(1):195-206
Cellular and molecular life sciences : CMLS 2021 Jan;78(1):195-206
miR-937-5p targets SOX17 to modulate breast cancer cell cycle and cell proliferation through the Wnt signaling pathway.
Xiong X, Xu W, Gong J, Wang L, Dai M, Chen G, Yuan L
Cellular signalling 2021 Jan;77:109818
Cellular signalling 2021 Jan;77:109818
Isoorientin exerts a urate-lowering effect through inhibition of xanthine oxidase and regulation of the TLR4-NLRP3 inflammasome signaling pathway.
An MF, Wang MY, Shen C, Sun ZR, Zhao YL, Wang XJ, Sheng J
Journal of natural medicines 2021 Jan;75(1):129-141
Journal of natural medicines 2021 Jan;75(1):129-141
Layer-specific strain for assessing the effect of naringin on systolic myocardial dysfunction induced by sepsis and its underlying mechanisms.
Sun LJ, Qiao W, Xiao YJ, Ren WD
The Journal of international medical research 2021 Jan;49(1):300060520986369
The Journal of international medical research 2021 Jan;49(1):300060520986369
Esomeprazole overcomes paclitaxel-resistance and enhances anticancer effects of paclitaxel by inducing autophagy in A549/Taxol cells.
Bai Z, Ding N, Ge J, Wang Y, Wang L, Wu N, Wei Q, Xu S, Liu X, Zhou G
Cell biology international 2021 Jan;45(1):177-187
Cell biology international 2021 Jan;45(1):177-187
Topotecan induces hepatocellular injury via ASCT2 mediated oxidative stress.
Zhou G, Qin M, Zhang X, Yang J, Yu H
Gastroenterologia y hepatologia 2021 Jan;44(1):1-12
Gastroenterologia y hepatologia 2021 Jan;44(1):1-12
Small extracellular vesicles containing miR-30a-3p attenuate the migration and invasion of hepatocellular carcinoma by targeting SNAP23 gene.
Liu C, Zhou X, Long Q, Zeng H, Sun Q, Chen Y, Wu D, Liu L
Oncogene 2021 Jan;40(2):233-245
Oncogene 2021 Jan;40(2):233-245
FBW7-NRA41-SCD1 axis synchronously regulates apoptosis and ferroptosis in pancreatic cancer cells.
Ye Z, Zhuo Q, Hu Q, Xu X, Mengqi Liu, Zhang Z, Xu W, Liu W, Fan G, Qin Y, Yu X, Ji S
Redox biology 2021 Jan;38:101807
Redox biology 2021 Jan;38:101807
Senolytic therapy ameliorates renal fibrosis postacute kidney injury by alleviating renal senescence.
Li C, Shen Y, Huang L, Liu C, Wang J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Jan;35(1):e21229
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Jan;35(1):e21229
Neuropathy-associated histidyl-tRNA synthetase variants attenuate protein synthesis in vitro and disrupt axon outgrowth in developing zebrafish.
Mullen P, Abbott JA, Wellman T, Aktar M, Fjeld C, Demeler B, Ebert AM, Francklyn CS
The FEBS journal 2021 Jan;288(1):142-159
The FEBS journal 2021 Jan;288(1):142-159
Arsenic exposure increased expression of HOTAIR and LincRNA-p21 in vivo and vitro.
Tan J, Sun M, Luo Q, Sun H, Wang M, Jiang C, Li S, He Y
Environmental science and pollution research international 2021 Jan;28(1):587-596
Environmental science and pollution research international 2021 Jan;28(1):587-596
CircRNA-vgll3 promotes osteogenic differentiation of adipose-derived mesenchymal stem cells via modulating miRNA-dependent integrin α5 expression.
Zhang D, Ni N, Wang Y, Tang Z, Gao H, Ju Y, Sun N, He X, Gu P, Fan X
Cell death and differentiation 2021 Jan;28(1):283-302
Cell death and differentiation 2021 Jan;28(1):283-302
SNHG1 represses the anti-cancer roles of baicalein in cervical cancer through regulating miR-3127-5p/FZD4/Wnt/β-catenin signaling.
Yu X, Xia J, Cao Y, Tang L, Tang X, Li Z
Experimental biology and medicine (Maywood, N.J.) 2021 Jan;246(1):20-30
Experimental biology and medicine (Maywood, N.J.) 2021 Jan;246(1):20-30
Endogenous promoter-driven sgRNA for monitoring the expression of low-abundance transcripts and lncRNAs.
Gao N, Hu J, He B, Ji Z, Hu X, Huang J, Wei Y, Peng J, Wei Y, Zhou Y, Shen X, Li H, Feng X, Xiao Q, Shi L, Sun Y, Zhou C, Zhou H, Yang H
Nature cell biology 2021 Jan;23(1):99-108
Nature cell biology 2021 Jan;23(1):99-108
Protection against Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice by Neferine, A Natural Product from Nelumbo nucifera Gaertn.
Min X, Guo Y, Zhou Y, Chen X
Cell journal 2021 Jan;22(4):523-531
Cell journal 2021 Jan;22(4):523-531
Quantitative proteomics reveals stage-specific protein regulation of triple negative breast cancer.
Lin Y, Lin L, Fu F, Wang C, Hu A, Xie J, Jiang M, Wang Z, Yang L, Guo R, Yang P, Shen H
Breast cancer research and treatment 2021 Jan;185(1):39-52
Breast cancer research and treatment 2021 Jan;185(1):39-52
Loss of WD2 subdomain of Apaf-1 forms an apoptosome structure which blocks activation of caspase-3 and caspase-9.
Noori AR, Tashakor A, Nikkhah M, Eriksson LA, Hosseinkhani S, Fearnhead HO
Biochimie 2021 Jan;180:23-29
Biochimie 2021 Jan;180:23-29
Characteristics of inflammation process in monocrotaline-induced pulmonary arterial hypertension in rats.
Tang C, Luo Y, Li S, Huang B, Xu S, Li L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jan;133:111081
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jan;133:111081
Improved BMP2-CPC-stimulated osteogenesis in vitro and in vivo via modulation of macrophage polarization.
Shen H, Shi J, Zhi Y, Yang X, Yuan Y, Si J, Shen SGF
Materials science & engineering. C, Materials for biological applications 2021 Jan;118:111471
Materials science & engineering. C, Materials for biological applications 2021 Jan;118:111471
Hyperglycemia-reduced NAD+ biosynthesis impairs corneal epithelial wound healing in diabetic mice.
Li Y, Li J, Zhao C, Yang L, Qi X, Wang X, Zhou Q, Shi W
Metabolism: clinical and experimental 2021 Jan;114:154402
Metabolism: clinical and experimental 2021 Jan;114:154402
MiR-362 suppresses cervical cancer progression via directly targeting BAP31 and activating TGFβ/Smad pathway.
Yang S, Sun Y, Jiang D, Wang J, Dang E, Li Z, Zhou J, Lu Y, Shi J, Tao L, Wang J, Jin B, Zheng L, Yang K
Cancer medicine 2021 Jan;10(1):305-316
Cancer medicine 2021 Jan;10(1):305-316
Identification of an N6-methyladenosine-mediated positive feedback loop that promotes Epstein-Barr virus infection.
Dai DL, Li X, Wang L, Xie C, Jin Y, Zeng MS, Zuo Z, Xia TL
The Journal of biological chemistry 2021 Jan-Jun;296:100547
The Journal of biological chemistry 2021 Jan-Jun;296:100547
Androgen receptor splicing variant 7 (ARV7) inhibits docetaxel sensitivity by inactivating the spindle assembly checkpoint.
Yu B, Liu Y, Luo H, Fu J, Li Y, Shao C
The Journal of biological chemistry 2021 Jan-Jun;296:100276
The Journal of biological chemistry 2021 Jan-Jun;296:100276
The ATPase ATP6V1A facilitates rabies virus replication by promoting virion uncoating and interacting with the viral matrix protein.
Liu X, Li F, Zhang J, Wang L, Wang J, Wen Z, Wang Z, Shuai L, Wang X, Ge J, Zhao D, Bu Z
The Journal of biological chemistry 2021 Jan-Jun;296:100096
The Journal of biological chemistry 2021 Jan-Jun;296:100096
Protective Effect of Retrograde Reperfusion Against Hepatic Autophagy Impairment in Rat Liver Transplantation.
Cheng Y, Lan H, Chen Y, Jiang Y, Chen Y
Transplantation proceedings 2021 Jan-Feb;53(1):443-449
Transplantation proceedings 2021 Jan-Feb;53(1):443-449
The EGFR-HSF1 axis accelerates the tumorigenesis of pancreatic cancer.
Qian W, Chen K, Qin T, Xiao Y, Li J, Yue Y, Zhou C, Ma J, Duan W, Lei J, Han L, Li L, Shen X, Wu Z, Ma Q, Wang Z
Journal of experimental & clinical cancer research : CR 2021 Jan 9;40(1):25
Journal of experimental & clinical cancer research : CR 2021 Jan 9;40(1):25
Identification of the atypical cadherin FAT1 as a novel glypican-3 interacting protein in liver cancer cells.
Meng P, Zhang YF, Zhang W, Chen X, Xu T, Hu S, Liang X, Feng M, Yang X, Ho M
Scientific reports 2021 Jan 8;11(1):40
Scientific reports 2021 Jan 8;11(1):40
Cell surface GRP78 regulates BACE2 via lysosome-dependent manner to maintain mesenchymal phenotype of glioma stem cells.
Chen Z, Wang H, Zhang Z, Xu J, Qi Y, Xue H, Gao Z, Zhao R, Wang S, Zhang S, Qiu W, Guo X, Li G
Journal of experimental & clinical cancer research : CR 2021 Jan 7;40(1):20
Journal of experimental & clinical cancer research : CR 2021 Jan 7;40(1):20
Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes.
Karki R, Sharma BR, Tuladhar S, Williams EP, Zalduondo L, Samir P, Zheng M, Sundaram B, Banoth B, Malireddi RKS, Schreiner P, Neale G, Vogel P, Webby R, Jonsson CB, Kanneganti TD
Cell 2021 Jan 7;184(1):149-168.e17
Cell 2021 Jan 7;184(1):149-168.e17
β-Conglycinin induces the formation of neutrophil extracellular traps dependent on NADPH oxidase-derived ROS, PAD4, ERK1/2 and p38 signaling pathways in mice.
Liu X, Fu Y, Wang J, Wu D, Li S, Wang C, Yang Z, Zhou E
Food & function 2021 Jan 7;12(1):154-161
Food & function 2021 Jan 7;12(1):154-161
Yangonin inhibits ethanol-induced hepatocyte senescence via miR-194/FXR axis.
Dong R, Wang X, Wang L, Wang C, Huang K, Fu T, Liu K, Wu J, Sun H, Meng Q
European journal of pharmacology 2021 Jan 5;890:173653
European journal of pharmacology 2021 Jan 5;890:173653
Progranulin induces immune escape in breast cancer via up-regulating PD-L1 expression on tumor-associated macrophages (TAMs) and promoting CD8+ T cell exclusion.
Fang W, Zhou T, Shi H, Yao M, Zhang D, Qian H, Zeng Q, Wang Y, Jin F, Chai C, Chen T
Journal of experimental & clinical cancer research : CR 2021 Jan 4;40(1):4
Journal of experimental & clinical cancer research : CR 2021 Jan 4;40(1):4
NEO100 enables brain delivery of blood‒brain barrier impermeable therapeutics.
Wang W, Marín-Ramos NI, He H, Zeng S, Cho HY, Swenson SD, Zheng L, Epstein AL, Schönthal AH, Hofman FM, Chen L, Chen TC
Neuro-oncology 2021 Jan 30;23(1):63-75
Neuro-oncology 2021 Jan 30;23(1):63-75
Effect of Pregnane X Receptor on CYP3A29 Expression in Porcine Alveolar Macrophages during Mycoplasma hyopneumoniae Infection.
Yang X, Xing F, Wang L, Zhao W, Fu Y, Tu F, Li B, Fang X, Ren S
Animals : an open access journal from MDPI 2021 Jan 30;11(2)
Animals : an open access journal from MDPI 2021 Jan 30;11(2)
Effects of different concentrations of coated nano zinc oxide material on fecal bacterial composition and intestinal barrier in weaned piglets.
Liu H, Bai M, Xu K, Zhou J, Zhang X, Yu R, Huang R, Yin Y
Journal of the science of food and agriculture 2021 Jan 30;101(2):735-745
Journal of the science of food and agriculture 2021 Jan 30;101(2):735-745
ADAM15 Participates in Tick-Borne Encephalitis Virus Replication.
Yang Q, Pei R, Wang Y, Zhou Y, Yang M, Chen X, Chen J
Journal of virology 2021 Jan 28;95(4)
Journal of virology 2021 Jan 28;95(4)
Angiogenesis is promoted by exosomal DPP4 derived from 5-fluorouracil-resistant colon cancer cells.
Zheng X, Liu J, Li X, Tian R, Shang K, Dong X, Cao B
Cancer letters 2021 Jan 28;497:190-201
Cancer letters 2021 Jan 28;497:190-201
Absolute configuration of tetrandrine and isotetrandrine influences their anti-proliferation effects in human T cells via different regulation of NF-κB.
Xu W, Kusano J, Chen S, Yamamoto R, Matsuda H, Hara Y, Fujii Y, Hayashi S, Tanaka S, Sugiyama K, Yamada H, Hirano T
Zeitschrift fur Naturforschung. C, Journal of biosciences 2021 Jan 27;76(1-2):21-25
Zeitschrift fur Naturforschung. C, Journal of biosciences 2021 Jan 27;76(1-2):21-25
Arsenite induce neurotoxicity of common carp: Involvement of blood brain barrier, apoptosis and autophagy, and subsequently relieved by zinc (Ⅱ) supplementation.
Wang Y, Zhao H, Liu Y, Guo M, Tian Y, Huang P, Xing M
Aquatic toxicology (Amsterdam, Netherlands) 2021 Jan 25;232:105765
Aquatic toxicology (Amsterdam, Netherlands) 2021 Jan 25;232:105765
MicroRNA-193a-5p Regulates the Synthesis of Polyunsaturated Fatty Acids by Targeting Fatty Acid Desaturase 1 (FADS1) in Bovine Mammary Epithelial Cells.
Fan Y, Arbab AAI, Zhang H, Yang Y, Lu X, Han Z, Yang Z
Biomolecules 2021 Jan 25;11(2)
Biomolecules 2021 Jan 25;11(2)
Circular RNA circRUNX1 promotes papillary thyroid cancer progression and metastasis by sponging MiR-296-3p and regulating DDHD2 expression.
Chu J, Tao L, Yao T, Chen Z, Lu X, Gao L, Fang L, Chen J, He G, Shen S, Zhang D
Cell death & disease 2021 Jan 21;12(1):112
Cell death & disease 2021 Jan 21;12(1):112
Diosmetin Ameliorates Nonalcoholic Steatohepatitis through Modulating Lipogenesis and Inflammatory Response in a STAT1/CXCL10-Dependent Manner.
Luo N, Yang C, Zhu Y, Chen Q, Zhang B
Journal of agricultural and food chemistry 2021 Jan 20;69(2):655-667
Journal of agricultural and food chemistry 2021 Jan 20;69(2):655-667
Perampanel Stimulates Mitochondrial Biogenesis in Neuronal Cells through Activation of the SIRT1/PGC-1α Signaling Pathway.
Jiang Y, Li D, Du Z, Li J, Lu R, Zhou Q, Wang Q, Zhu H
ACS chemical neuroscience 2021 Jan 20;12(2):323-329
ACS chemical neuroscience 2021 Jan 20;12(2):323-329
Downregulation of metabotropic glutamate receptor 5 alleviates central sensitization by activating autophagy via inhibiting mTOR pathway in a rat model of chronic migraine.
Niu Y, Zeng X, Qin G, Zhang D, Zhou J, Chen L
Neuroscience letters 2021 Jan 19;743:135552
Neuroscience letters 2021 Jan 19;743:135552
Mutations in GDAP1 Influence Structure and Function of the Trans-Golgi Network.
Binięda K, Rzepnikowska W, Kolakowski D, Kaminska J, Szczepankiewicz AA, Nieznańska H, Kochański A, Kabzińska D
International journal of molecular sciences 2021 Jan 18;22(2)
International journal of molecular sciences 2021 Jan 18;22(2)
Synergism of HPV and MNNG repress miR-218 promoting Het-1A cell malignant transformation by targeting GAB2.
Zhang Y, Zheng Y, Pan E, Zhao C, Zhang H, Liu R, Wang S, Pu Y, Yin L
Toxicology 2021 Jan 15;447:152635
Toxicology 2021 Jan 15;447:152635
Hypoxic conditioned promotes the proliferation of human olfactory mucosa mesenchymal stem cells and relevant lncRNA and mRNA analysis.
He J, Huang Y, Liu J, Ge L, Tang X, Lu M, Hu Z
Life sciences 2021 Jan 15;265:118861
Life sciences 2021 Jan 15;265:118861
Microcystin-leucine arginine induced the apoptosis of GnRH neurons by activating the endoplasmic reticulum stress resulting in a decrease of serum testosterone level in mice.
Jin H, Hou J, Meng X, Ma T, Wang B, Liu Z, Sha X, Ding J, Han X
Ecotoxicology and environmental safety 2021 Jan 15;208:111748
Ecotoxicology and environmental safety 2021 Jan 15;208:111748
Zinc offers splenic protection through suppressing PERK/IRE1-driven apoptosis pathway in common carp (Cyprinus carpio) under arsenic stress.
Wang Y, Zhao H, Mu M, Guo M, Xing M
Ecotoxicology and environmental safety 2021 Jan 15;208:111473
Ecotoxicology and environmental safety 2021 Jan 15;208:111473
Curcumin ameliorates mercuric chloride-induced liver injury via modulating cytochrome P450 signaling and Nrf2/HO-1 pathway.
Li S, Wang X, Xiao Y, Wang Y, Wan Y, Li X, Li Q, Tang X, Cai D, Ran B, Wu C
Ecotoxicology and environmental safety 2021 Jan 15;208:111426
Ecotoxicology and environmental safety 2021 Jan 15;208:111426
iASPP protects the heart from ischemia injury by inhibiting p53 expression and cardiomyocyte apoptosis.
Yagudin T, Zhao Y, Gao H, Zhang Y, Yang Y, Zhang X, Ma W, Daba TM, Ishmetov V, Kang K, Yang B, Pan Z
Acta biochimica et biophysica Sinica 2021 Jan 12;53(1):102-111
Acta biochimica et biophysica Sinica 2021 Jan 12;53(1):102-111
Salvia miltiorrhiza stems and leaves total phenolic acids combination with tanshinone protect against DSS-induced ulcerative colitis through inhibiting TLR4/PI3K/AKT/mTOR signaling pathway in mice.
Peng KY, Gu JF, Su SL, Zhu Y, Guo JM, Qian DW, Duan JA
Journal of ethnopharmacology 2021 Jan 10;264:113052
Journal of ethnopharmacology 2021 Jan 10;264:113052
Aptamer-based CRISPR/Cas12a assay for the ultrasensitive detection of extracellular vesicle proteins.
Li H, Xing S, Xu J, He Y, Lai Y, Wang Y, Zhang G, Guo S, Deng M, Zeng M, Liu W
Talanta 2021 Jan 1;221:121670
Talanta 2021 Jan 1;221:121670
An identified PfHMGB1 promotes microcystin-LR-induced liver injury of yellow catfish (Pelteobagrus fulvidraco).
Wang Y, Xiao X, Wang F, Yang Z, Yue J, Shi J, Ke F, Xie Z, Fan Y
Ecotoxicology and environmental safety 2021 Jan 1;207:111266
Ecotoxicology and environmental safety 2021 Jan 1;207:111266
The impact of SAMHD1 expression and mutation status in mantle cell lymphoma: An analysis of the MCL Younger and Elderly trial.
Roider T, Wang X, Hüttl K, Müller-Tidow C, Klapper W, Rosenwald A, Stewart JP, de Castro DG, Dreger P, Hermine O, Kluin-Nelemans HC, Grabe N, Dreyling M, Pott C, Ott G, Hoster E, Dietrich S
International journal of cancer 2021 Jan 1;148(1):150-160
International journal of cancer 2021 Jan 1;148(1):150-160
Role of Slit2 upregulation in recurrent miscarriage through regulation of stromal decidualization.
Chen J, Liu J, Gao S, Qiu Y, Wang Y, Zhang Y, Gao L, Qi G, Wu Y, Lash GE, Li P
Placenta 2021 Jan 1;103:1-9
Placenta 2021 Jan 1;103:1-9
mTORC1-mediated amino acid signaling is critical for cell fate determination under transplant-induced stress.
Cheng X, Ge M, Zhu S, Li D, Wang R, Xu Q, Chen Z, Xie S, Liu H
FEBS letters 2021 Feb;595(4):462-475
FEBS letters 2021 Feb;595(4):462-475
Mutation analysis of MFSD8 in an amyotrophic lateral sclerosis cohort from mainland China.
Huang L, Liu Z, Yuan Y, Shen L, Jiang H, Tang B, Wang J, Lei L
The European journal of neuroscience 2021 Feb;53(4):1197-1206
The European journal of neuroscience 2021 Feb;53(4):1197-1206
lncRNA NEAT1 ameliorates LPS‑induced inflammation in MG63 cells by activating autophagy and suppressing the NLRP3 inflammasome.
Dai W, Wang M, Wang P, Wen J, Wang J, Cha S, Xiao X, He Y, Shu R, Bai D
International journal of molecular medicine 2021 Feb;47(2):607-620
International journal of molecular medicine 2021 Feb;47(2):607-620
The miR-145-5p/CD36 pathway mediates PCB2-induced apoptosis in MCF-7 cells.
Yuan Y, Xue C, Wu Q, Wang M, Liu J, Zhang L, Xing Q, Liang J, Wu H, Chen Z
Genes & genomics 2021 Feb;43(2):161-171
Genes & genomics 2021 Feb;43(2):161-171
Hypoxia-induced PLOD1 overexpression contributes to the malignant phenotype of glioblastoma via NF-κB signaling.
Wang Z, Shi Y, Ying C, Jiang Y, Hu J
Oncogene 2021 Feb;40(8):1458-1475
Oncogene 2021 Feb;40(8):1458-1475
Activation of the G Protein-Coupled Estrogen Receptor Prevented the Development of Acute Colitis by Protecting the Crypt Cell.
Wang Q, Li Z, Liu K, Liu J, Chai S, Chen G, Wen S, Ming T, Wang J, Ma Y, Zeng H, Liu C, Xue B
The Journal of pharmacology and experimental therapeutics 2021 Feb;376(2):281-293
The Journal of pharmacology and experimental therapeutics 2021 Feb;376(2):281-293
TAR DNA-Binding Protein 43 is Cleaved by the Protease 3C of Enterovirus A71.
Wo X, Yuan Y, Xu Y, Chen Y, Wang Y, Zhao S, Lin L, Zhong X, Wang Y, Zhong Z, Zhao W
Virologica Sinica 2021 Feb;36(1):95-103
Virologica Sinica 2021 Feb;36(1):95-103
Enhancer II-targeted dsRNA decreases GDNF expression via histone H3K9 trimethylation to inhibit glioblastoma progression.
Zhang B, Han X, Gao Q, Liu J, Li S, Zha W, Wang X, Guo X, Gao D
Brain research bulletin 2021 Feb;167:22-32
Brain research bulletin 2021 Feb;167:22-32
Upregulated Nmnat2 causes neuronal death and increases seizure susceptibility in temporal lobe epilepsy.
Wu H, Meng Q, Zhang Y, Li H, Liu Y, Dong S, Liu B, Zhang H
Brain research bulletin 2021 Feb;167:1-10
Brain research bulletin 2021 Feb;167:1-10
Piezo2 channel in nodose ganglia neurons is essential in controlling hypertension in a pathway regulated directly by Nedd4-2.
Huo L, Gao Y, Zhang D, Wang S, Han Y, Men H, Yang Z, Qin X, Wang R, Kong D, Bai H, Zhang H, Zhang W, Jia Z
Pharmacological research 2021 Feb;164:105391
Pharmacological research 2021 Feb;164:105391
Triptolide inhibits epithelial-mesenchymal transition phenotype through the p70S6k/GSK3/β-catenin signaling pathway in taxol-resistant human lung adenocarcinoma.
Tian Y, Li P, Xiao Z, Zhou J, Xue X, Jiang N, Peng C, Wu L, Tian H, Popper H, Poh ME, Marcucci F, Zhang C, Zhao X
Translational lung cancer research 2021 Feb;10(2):1007-1019
Translational lung cancer research 2021 Feb;10(2):1007-1019
Tregs facilitate obesity and insulin resistance via a Blimp-1/IL-10 axis.
Beppu LY, Mooli RGR, Qu X, Marrero GJ, Finley CA, Fooks AN, Mullen ZP, Frias AB Jr, Sipula I, Xie B, Helfrich KE, Watkins SC, Poholek AC, Ramakrishnan SK, Jurczak MJ, D'Cruz LM
JCI insight 2021 Feb 8;6(3)
JCI insight 2021 Feb 8;6(3)
NOGOB receptor-mediated RAS signaling pathway is a target for suppressing proliferating hemangioma.
Hu W, Liu Z, Salato V, North PE, Bischoff J, Kumar SN, Fang Z, Rajan S, Hussain MM, Miao QR
JCI insight 2021 Feb 8;6(3)
JCI insight 2021 Feb 8;6(3)
Angiomotin Counteracts the Negative Regulatory Effect of Host WWOX on Viral PPxY-Mediated Egress.
Liang J, Ruthel G, Sagum CA, Bedford MT, Sidhu SS, Sudol M, Jaladanki CK, Fan H, Freedman BD, Harty RN
Journal of virology 2021 Feb 3;
Journal of virology 2021 Feb 3;
Fork head box M1 regulates vascular endothelial growth factor-A expression to promote the angiogenesis and tumor cell growth of gallbladder cancer.
Wang RT, Miao RC, Zhang X, Yang GH, Mu YP, Zhang ZY, Qu K, Liu C
World journal of gastroenterology 2021 Feb 28;27(8):692-707
World journal of gastroenterology 2021 Feb 28;27(8):692-707
Hypoxic pancreatic stellate cell-derived exosomal mirnas promote proliferation and invasion of pancreatic cancer through the PTEN/AKT pathway.
Cao W, Zeng Z, He Z, Lei S
Aging 2021 Feb 26;13(5):7120-7132
Aging 2021 Feb 26;13(5):7120-7132
Human drug efflux transporter ABCC5 confers acquired resistance to pemetrexed in breast cancer.
Chen J, Wang Z, Gao S, Wu K, Bai F, Zhang Q, Wang H, Ye Q, Xu F, Sun H, Lu Y, Liu Y
Cancer cell international 2021 Feb 25;21(1):136
Cancer cell international 2021 Feb 25;21(1):136
Exosomes in ovarian cancer ascites promote epithelial-mesenchymal transition of ovarian cancer cells by delivery of miR-6780b-5p.
Cai J, Gong L, Li G, Guo J, Yi X, Wang Z
Cell death & disease 2021 Feb 24;12(2):210
Cell death & disease 2021 Feb 24;12(2):210
Impaired Intestinal Akkermansia muciniphila and Aryl Hydrocarbon Receptor Ligands Contribute to Nonalcoholic Fatty Liver Disease in Mice.
Shi Z, Lei H, Chen G, Yuan P, Cao Z, Ser HL, Zhu X, Wu F, Liu C, Dong M, Song Y, Guo Y, Chen C, Hu K, Zhu Y, Zeng XA, Zhou J, Lu Y, Patterson AD, Zhang L
mSystems 2021 Feb 23;6(1)
mSystems 2021 Feb 23;6(1)
Comparison of content-toxicity-activity of six ingenane-type diterpenoids between Euphorbia kansui before and after stir-fried with vinegar by using UFLC-MS/MS, zebrafish embryos and HT-29 cells.
Zhou SK, Zhang Y, Ju YH, Zhang Q, Luo D, Cao YD, Yao WF, Tang YP, Zhang L
Journal of pharmaceutical and biomedical analysis 2021 Feb 20;195:113828
Journal of pharmaceutical and biomedical analysis 2021 Feb 20;195:113828
Small extracellular vesicle-mediated Hsp70 intercellular delivery enhances breast cancer adriamycin resistance.
Hu W, Xu Z, Zhu S, Sun W, Wang X, Tan C, Zhang Y, Zhang G, Xu Y, Tang J
Free radical biology & medicine 2021 Feb 20;164:85-95
Free radical biology & medicine 2021 Feb 20;164:85-95
Differential mitochondrial proteomic analysis of A549 cells infected with avian influenza virus subtypes H5 and H9.
Yang Y, Zhang Y, Yang C, Fang F, Wang Y, Chang H, Chen Z, Chen P
Virology journal 2021 Feb 18;18(1):39
Virology journal 2021 Feb 18;18(1):39
Polyamine Analog Diethylnorspermidine Restricts Coxsackievirus B3 and Is Overcome by 2A Protease Mutation In Vitro.
Hulsebosch BM, Mounce BC
Viruses 2021 Feb 16;13(2)
Viruses 2021 Feb 16;13(2)
Down-regulation of A3AR signaling by IL-6-induced GRK2 activation contributes to Th17 cell differentiation.
Hu S, Guo P, Wang Z, Zhou Z, Wang R, Zhang M, Tao J, Tai Y, Zhou W, Wei W, Wang Q
Experimental cell research 2021 Feb 15;399(2):112482
Experimental cell research 2021 Feb 15;399(2):112482
Circ_0119872 promotes uveal melanoma development by regulating the miR-622/G3BP1 axis and downstream signalling pathways.
Liu S, Chen L, Chen H, Xu K, Peng X, Zhang M
Journal of experimental & clinical cancer research : CR 2021 Feb 12;40(1):66
Journal of experimental & clinical cancer research : CR 2021 Feb 12;40(1):66
The long noncoding RNA KTN1-AS1 promotes bladder cancer tumorigenesis via KTN1 cis-activation and the consequent initiation of Rho GTPase-mediated signaling.
Hu X, Xiang L, He D, Zhu R, Fang J, Wang Z, Cao K
Clinical science (London, England : 1979) 2021 Feb 12;135(3):555-574
Clinical science (London, England : 1979) 2021 Feb 12;135(3):555-574
Protective role of serpina3c as a novel thrombin inhibitor against atherosclerosis in mice.
Qian LL, Ji JJ, Guo JQ, Wu YP, Ma GS, Yao YY
Clinical science (London, England : 1979) 2021 Feb 12;135(3):447-463
Clinical science (London, England : 1979) 2021 Feb 12;135(3):447-463
QiShenYiQi pill activates autophagy to attenuate reactive myocardial fibrosis via the PI3K/AKT/mTOR pathway.
Lv S, Yuan P, Lu C, Dong J, Li M, Qu F, Zhu Y, Zhang J
Aging 2021 Feb 11;13(4):5525-5538
Aging 2021 Feb 11;13(4):5525-5538
Diosgenin alleviates hypercholesterolemia via SRB1/CES-1/CYP7A1/FXR pathway in high-fat diet-fed rats.
Yu L, Lu H, Yang X, Li R, Shi J, Yu Y, Ma C, Sun F, Zhang S, Zhang F
Toxicology and applied pharmacology 2021 Feb 1;412:115388
Toxicology and applied pharmacology 2021 Feb 1;412:115388
A novel tonicity-responsive microRNA miR-23a-5p modulates renal cell survival under osmotic stress through targeting heat shock protein 70 HSPA1B.
Kang K, Liao X, Li Q, Chen J, Niu Y, Zeng Y, Xia S, Zeng L, Liu S, Gou D
American journal of physiology. Cell physiology 2021 Feb 1;320(2):C225-C239
American journal of physiology. Cell physiology 2021 Feb 1;320(2):C225-C239
NF-κB pathway play a role in SCD1 deficiency-induced ceramide de novo synthesis.
Zheng RH, Zhang YB, Qiu FN, Liu ZH, Han Y, Huang R, Zhao Y, Yao P, Qiu Y, Ren J
Cancer biology & therapy 2021 Feb 1;22(2):164-174
Cancer biology & therapy 2021 Feb 1;22(2):164-174
Vascular endothelial cell-secreted exosomes facilitate osteoarthritis pathogenesis by promoting chondrocyte apoptosis.
Yang RZ, Zheng HL, Xu WN, Zheng XF, Li B, Jiang LS, Jiang SD
Aging 2021 Feb 1;13(3):4647-4662
Aging 2021 Feb 1;13(3):4647-4662
Red ginseng has stronger anti-aging effects compared to ginseng possibly due to its regulation of oxidative stress and the gut microbiota.
Peng X, Hao M, Zhao Y, Cai Y, Chen X, Chen H, Zhang Y, Dong L, Liu X, Ding C, Liu W, Yang M, Luo Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Dec;93:153772
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Dec;93:153772
IL-27 signalling promotes adipocyte thermogenesis and energy expenditure.
Wang Q, Li D, Cao G, Shi Q, Zhu J, Zhang M, Cheng H, Wen Q, Xu H, Zhu L, Zhang H, Perry RJ, Spadaro O, Yang Y, He S, Chen Y, Wang B, Li G, Liu Z, Yang C, Wu X, Zhou L, Zhou Q, Ju Z, Lu H, Xin Y, Yang X, Wang C, Liu Y, Shulman GI, Dixit VD, Lu L, Yang H, Flavell RA, Yin Z
Nature 2021 Dec;600(7888):314-318
Nature 2021 Dec;600(7888):314-318
CoCrMo-Nanoparticles induced peri-implant osteolysis by promoting osteoblast ferroptosis via regulating Nrf2-ARE signalling pathway.
Xu Y, Sang W, Zhong Y, Xue S, Yang M, Wang C, Lu H, Huan R, Mao X, Zhu L, He C, Ma J
Cell proliferation 2021 Dec;54(12):e13142
Cell proliferation 2021 Dec;54(12):e13142
Identification of autophagic target RAB13 with small-molecule inhibitor in low-grade glioma via integrated multi-omics approaches coupled with virtual screening of traditional Chinese medicine databases.
Su W, Liao M, Tan H, Chen Y, Zhao R, Jin W, Zhu S, Zhang Y, He L, Liu B
Cell proliferation 2021 Dec;54(12):e13135
Cell proliferation 2021 Dec;54(12):e13135
Semaglutide attenuates seizure severity and ameliorates cognitive dysfunction by blocking the NLR family pyrin domain containing 3 inflammasome in pentylenetetrazole‑kindled mice.
Wang L, Ding J, Zhu C, Guo B, Yang W, He W, Li X, Wang Y, Li W, Wang F, Sun T
International journal of molecular medicine 2021 Dec;48(6)
International journal of molecular medicine 2021 Dec;48(6)
Endoplasmic reticulum stress pathway mediates T-2 toxin-induced chondrocyte apoptosis.
Liu YN, Mu YD, Wang H, Zhang M, Shi YW, Mi G, Peng LX, Chen JH
Toxicology 2021 Dec;464:152989
Toxicology 2021 Dec;464:152989
FOXO1 inhibits prostate cancer cell proliferation via suppressing E2F1 activated NPRL2 expression.
Tang Y, Jiang L, Zhao X, Hu D, Zhao G, Luo S, Du X, Tang W
Cell biology international 2021 Dec;45(12):2510-2520
Cell biology international 2021 Dec;45(12):2510-2520
GLO 1 and PKCλ Regulate ALDH1-positive Breast Cancer Stem Cell Survival.
Motomura H, Tamori S, Yatani MA, Namiki A, Onaga C, Ozaki A, Takasawa R, Mano Y, Sato T, Hara Y, Sato K, Xiong Y, Harada Y, Hanawa T, Tanuma SI, Sasaki K, Ohno S, Akimoto K
Anticancer research 2021 Dec;41(12):5959-5971
Anticancer research 2021 Dec;41(12):5959-5971
The transcribed ultraconserved element uc.51 promotes the proliferation and metastasis of breast cancer by stabilizing NONO.
Shi X, Huang X, Chen R, Li Y, Xu Y, Zhang W, Zhu Q, Zha X, Wang J
Clinical & experimental metastasis 2021 Dec;38(6):551-571
Clinical & experimental metastasis 2021 Dec;38(6):551-571
ubtor Mutation Causes Motor Hyperactivity by Activating mTOR Signaling in Zebrafish.
Wang T, Zhou M, Zhang Q, Zhang C, Peng G
Neuroscience bulletin 2021 Dec;37(12):1658-1670
Neuroscience bulletin 2021 Dec;37(12):1658-1670
The flavonoid procyanidin C1 has senotherapeutic activity and increases lifespan in mice.
Xu Q, Fu Q, Li Z, Liu H, Wang Y, Lin X, He R, Zhang X, Ju Z, Campisi J, Kirkland JL, Sun Y
Nature metabolism 2021 Dec;3(12):1706-1726
Nature metabolism 2021 Dec;3(12):1706-1726
Caspase-6 promotes activation of the caspase-11-NLRP3 inflammasome during gram-negative bacterial infections.
Zheng M, Karki R, Kancharana B, Berns H, Pruett-Miller SM, Kanneganti TD
The Journal of biological chemistry 2021 Dec;297(6):101379
The Journal of biological chemistry 2021 Dec;297(6):101379
MEHP induces pyroptosis and autophagy alternation by cathepsin B activation in INS-1 cells.
Jiang L, Qiu T, Yao X, Chen H, Yao K, Sun X, Yang G, Jiang L, Zhang C, Wang N, Zhang H, Liu X
Environmental science and pollution research international 2021 Dec;28(47):66628-66642
Environmental science and pollution research international 2021 Dec;28(47):66628-66642
A bivalent cyclic RGD-siRNA conjugate enhances the antitumor effect of apatinib via co-inhibiting VEGFR2 in non-small cell lung cancer xenografts.
Liao L, Cen B, Li G, Wei Y, Wang Z, Huang W, He S, Yuan Y, Ji A
Drug delivery 2021 Dec;28(1):1432-1442
Drug delivery 2021 Dec;28(1):1432-1442
Exosomal ANXA2 derived from ovarian cancer cells regulates epithelial-mesenchymal plasticity of human peritoneal mesothelial cells.
Gao L, Nie X, Gou R, Hu Y, Dong H, Li X, Lin B
Journal of cellular and molecular medicine 2021 Dec;25(23):10916-10929
Journal of cellular and molecular medicine 2021 Dec;25(23):10916-10929
FPR2 serves a role in recurrent spontaneous abortion by regulating trophoblast function via the PI3K/AKT signaling pathway.
Li A, Li S, Zhang C, Fang Z, Sun Y, Peng Y, Wang X, Zhang M
Molecular medicine reports 2021 Dec;24(6)
Molecular medicine reports 2021 Dec;24(6)
Knockdown of TRIM9 attenuates irinotecan‑induced intestinal mucositis in IEC‑6 cells by regulating DUSP6 expression via the P38 pathway.
Zhao W, Wang Q
Molecular medicine reports 2021 Dec;24(6)
Molecular medicine reports 2021 Dec;24(6)
Suppression of ER-stress induction of GRP78 as an anti-neoplastic mechanism of the cardiac glycoside Lanatoside C in pancreatic cancer: Lanatoside C suppresses GRP78 stress induction.
Ha DP, Tsai YL, Lee AS
Neoplasia (New York, N.Y.) 2021 Dec;23(12):1213-1226
Neoplasia (New York, N.Y.) 2021 Dec;23(12):1213-1226
Danshensu derivative ADTM ameliorates CCl4‑induced acute liver injury in mice through inhibiting oxidative stress and apoptosis.
Jia S, Chen Q, Wu J, Yao X, Shao J, Cheng X, Zhang C, Cen D, Wang Y, Shen Z, Shan L, Yao X
Pathology, research and practice 2021 Dec;228:153656
Pathology, research and practice 2021 Dec;228:153656
Mel1b and Mel1c melatonin receptors mediate green light-induced secretion of growth hormone in chick adenohypophysis cells via the AC/PKA and ERK1/2 signalling pathways.
Liu X, Wang L, Wang Z, Dong Y, Chen Y, Cao J
Journal of photochemistry and photobiology. B, Biology 2021 Dec;225:112322
Journal of photochemistry and photobiology. B, Biology 2021 Dec;225:112322
Arsenic (III) induces oxidative stress and inflammation in the gills of common carp, which is ameliorated by zinc (II).
Lu H, Zhao H, Wang Y, Guo M, Mu M, Liu Y, Nie X, Huang P, Xing M
Journal of inorganic biochemistry 2021 Dec;225:111617
Journal of inorganic biochemistry 2021 Dec;225:111617
Knockdown of METTL14 suppresses the malignant progression of non-small cell lung cancer by reducing Twist expression.
Yang F, Yuan WQ, Li J, Luo YQ
Oncology letters 2021 Dec;22(6):847
Oncology letters 2021 Dec;22(6):847
CMPK2 accelerates liver ischemia/reperfusion injury via the NLRP3 signaling pathway.
Luo Y, Zheng D, Mou T, Pu J, Huang Z, Chen W, Zhang Y, Wu Z
Experimental and therapeutic medicine 2021 Dec;22(6):1358
Experimental and therapeutic medicine 2021 Dec;22(6):1358
Antidepressant effect of catalpol on corticosterone-induced depressive-like behavior involves the inhibition of HPA axis hyperactivity, central inflammation and oxidative damage probably via dual regulation of NF-κB and Nrf2.
Song L, Wu X, Wang J, Guan Y, Zhang Y, Gong M, Wang Y, Li B
Brain research bulletin 2021 Dec;177:81-91
Brain research bulletin 2021 Dec;177:81-91
Small molecule targeting topoisomerase 3β for cancer therapy.
Zhang X, Wang L, Zhang Q, Lyu S, Zhu D, Shen M, Ke X, Qu Y
Pharmacological research 2021 Dec;174:105927
Pharmacological research 2021 Dec;174:105927
Dihydroartemisinin ameliorates retinal vascular dysfunction in diabetes mellitus via the FASN/Kmal-mTOR/SREBP1 feedback loop.
Gu C, She X, Zhou C, Su T, He S, Meng C, Gu Q, Luo D, Zheng Z, Qiu Q
Pharmacological research 2021 Dec;174:105871
Pharmacological research 2021 Dec;174:105871
DNA damage-inducible transcript 3 restrains osteoclast differentiation and function.
Yang B, Sun H, Jia M, He Y, Luo Y, Wang T, Wu Y, Wang J
Bone 2021 Dec;153:116162
Bone 2021 Dec;153:116162
Acupuncture regulates the autophagy of ovarian granulosa cells in polycystic ovarian syndrome ovulation disorder by inhibiting the PI3K/AKT/mTOR pathway through LncMEG3.
Chen X, Tang H, Liang Y, Wu P, Xie L, Ding Y, Yang P, Long B, Lin J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Dec;144:112288
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Dec;144:112288
Selenoprotein S attenuates high glucose and/or ox-LDL-induced endothelium injury by regulating Akt/mTOR signaling and autophagy.
Wang Z, Li Y, Yao J, Yu S, Yu H, Men L, Du J
The international journal of biochemistry & cell biology 2021 Dec;141:106111
The international journal of biochemistry & cell biology 2021 Dec;141:106111
Silencing FYVE, RhoGEF, and PH domain containing 1 (FGD1) suppresses melanoma progression by inhibiting PI3K/AKT signaling pathway.
Niu Z, Li Y, Xu Y, Jiang W, Tao R, Chen Y, Han Y
Bioengineered 2021 Dec;12(2):12193-12205
Bioengineered 2021 Dec;12(2):12193-12205
Role of Rho guanine nucleotide exchange factors in non-small cell lung cancer.
Zeng RJ, Xie WJ, Zheng CW, Chen WX, Wang SM, Li Z, Cheng CB, Zou HY, Xu LY, Li EM
Bioengineered 2021 Dec;12(2):11169-11187
Bioengineered 2021 Dec;12(2):11169-11187
Mechanistic insights into the renoprotective role of curcumin in cisplatin-induced acute kidney injury: network pharmacology analysis and experimental validation.
Hui Z, Dong QQ, Shu HP, Tu YC, Liao QQ, Yao LJ
Bioengineered 2021 Dec;12(2):11041-11056
Bioengineered 2021 Dec;12(2):11041-11056
Human umbilical vein endothelial cells derived-exosomes promote osteosarcoma cell stemness by activating Notch signaling pathway.
Yang J, Hu Y, Wang L, Sun X, Yu L, Guo W
Bioengineered 2021 Dec;12(2):11007-11017
Bioengineered 2021 Dec;12(2):11007-11017
A comprehensive genome-wide analysis of long non-coding RNA and mRNA expression profiles of JAK2V617F-positive classical myeloproliferative neoplasms.
Zhou J, Wu H, Guo C, Li B, Zhou LL, Liang AB, Fu JF
Bioengineered 2021 Dec;12(2):10564-10586
Bioengineered 2021 Dec;12(2):10564-10586
A virulent Bacillus cereus strain from deep-sea cold seep induces pyroptosis in a manner that involves NLRP3 inflammasome, JNK pathway, and lysosomal rupture.
Zhao Y, Jiang S, Zhang J, Guan XL, Sun BG, Sun L
Virulence 2021 Dec;12(1):1362-1376
Virulence 2021 Dec;12(1):1362-1376
ATR kinase activity promotes antibody class switch recombination in B cells through cell cycle regulation without suppressing DSB resection and microhomology usage.
Sun X, Liu M, Bai J, Xu J, Zhu C, Dong J, Chen C
Journal of leukocyte biology 2021 Dec;110(6):1101-1112
Journal of leukocyte biology 2021 Dec;110(6):1101-1112
GABAA receptor agonist muscimol rescues inhibitory microcircuit defects in the olfactory bulb and improves olfactory function in APP/PS1 transgenic mice.
Hu B, Geng C, Guo F, Liu Y, Zong YC, Hou XY
Neurobiology of aging 2021 Dec;108:47-57
Neurobiology of aging 2021 Dec;108:47-57
1β-Hydroxyalantolactone from Inulae Flos alleviated the progression of pulmonary fibrosis via inhibiting JNK/FOXO1/NF-κB pathway.
Yu B, Jin XQ, Yu WY, Dong YY, Ying HZ, Yu CH
International immunopharmacology 2021 Dec;101(Pt A):108339
International immunopharmacology 2021 Dec;101(Pt A):108339
Dietary hawthorn-leaves flavonoids improves ovarian function and liver lipid metabolism in aged breeder hens.
Dai H, Lv Z, Huang Z, Ye N, Li S, Jiang J, Cheng Y, Shi F
Poultry science 2021 Dec;100(12):101499
Poultry science 2021 Dec;100(12):101499
Mannan-binding lectin deficiency augments hepatic endoplasmic reticulum stress through IP3R-controlled calcium release.
Chen Y, Hu M, Deng F, Wang P, Lin J, Zheng Z, Liu Y, Dong L, Lu X, Chen Z, Zhou J, Zuo D
Cell calcium 2021 Dec;100:102477
Cell calcium 2021 Dec;100:102477
Acquiring high expression of suilysin enable non-epidemic Streptococccus suis to cause streptococcal toxic shock-like syndrome (STSLS) through NLRP3 inflammasome hyperactivation.
Xu L, Lin L, Lu X, Xiao P, Liu R, Wu M, Jin M, Zhang A
Emerging microbes & infections 2021 Dec;10(1):1309-1319
Emerging microbes & infections 2021 Dec;10(1):1309-1319
Oligomeric Aβ25-35 induces the tyrosine phosphorylation of PSD-95 by SrcPTKs in rat hippocampal CA1 subfield.
Wu GM, Du CP, Xu Y
The International journal of neuroscience 2021 Dec 9;:1-8
The International journal of neuroscience 2021 Dec 9;:1-8
MiRNA-132/212 regulates tight junction stabilization in blood-brain barrier after stroke.
Yan H, Kanki H, Matsumura S, Kawano T, Nishiyama K, Sugiyama S, Takemori H, Mochizuki H, Sasaki T
Cell death discovery 2021 Dec 8;7(1):380
Cell death discovery 2021 Dec 8;7(1):380
NLRP3 inflammasome signal pathway involves in Vibrio harveyi-induced inflammatory response in murine peritoneal macrophages in vitro.
Yu G, Wang J, Zhang W, Yang Q, Liu G, Wang L, Bello BK, Zhang X, Zhang T, Fan H, Zhao P, Liang W, Dong J
Acta biochimica et biophysica Sinica 2021 Dec 8;53(12):1590-1601
Acta biochimica et biophysica Sinica 2021 Dec 8;53(12):1590-1601
Transcriptional regulator CTR9 promotes hepatocellular carcinoma progression and metastasis via increasing PEG10 transcriptional activity.
Zhang B, Liu ZY, Wu R, Zhang CM, Cao K, Shan WG, Liu Z, Ji M, Tian ZL, Sethi G, Shi HL, Wang RH
Acta pharmacologica Sinica 2021 Dec 7;
Acta pharmacologica Sinica 2021 Dec 7;
ZNF382 controls mouse neuropathic pain via silencer-based epigenetic inhibition of Cxcl13 in DRG neurons.
Ma L, Yu L, Jiang BC, Wang J, Guo X, Huang Y, Ren J, Sun N, Gao DS, Ding H, Lu J, Zhou H, Zou L, Gao Y, Wang L, Sun K, Ming Y, Meng Z, Tao YX, Yan M
The Journal of experimental medicine 2021 Dec 6;218(12)
The Journal of experimental medicine 2021 Dec 6;218(12)
Diacerein attenuates vascular dysfunction by reducing inflammatory response and insulin resistance in type 2 diabetic rats.
He A, Shen J, Xue Y, Xiang Li, Li Y, Huang L, Lv D, Luo M
Biochemical and biophysical research communications 2021 Dec 31;585:68-74
Biochemical and biophysical research communications 2021 Dec 31;585:68-74
CD38 activation by monosodium urate crystals contributes to inflammatory responses in human and murine macrophages.
Wen S, Arakawa H, Tamai I
Biochemical and biophysical research communications 2021 Dec 3;581:6-11
Biochemical and biophysical research communications 2021 Dec 3;581:6-11
USP30-AS1 contributes to mitochondrial quality control in glioblastoma cells.
Wang N, Li J, Xin Q, Xu N
Biochemical and biophysical research communications 2021 Dec 3;581:31-37
Biochemical and biophysical research communications 2021 Dec 3;581:31-37
Heat stress affects fetal brain and intestinal function associated with the alterations of placental barrier in late pregnant mouse.
Guo H, Yang Y, Qiao Y, He J, Yao W, Zheng W
Ecotoxicology and environmental safety 2021 Dec 20;227:112916
Ecotoxicology and environmental safety 2021 Dec 20;227:112916
Interleukin-37 inhibits inflammation activation and disease severity of PM2.5-induced airway hyperresponsiveness.
Wang M, Hou S, Lu X, Li J, Li R, Yan X
Ecotoxicology and environmental safety 2021 Dec 20;227:112890
Ecotoxicology and environmental safety 2021 Dec 20;227:112890
Nucleosomes enter cells by clathrin- and caveolin-dependent endocytosis.
Wang H, Shan X, Ren M, Shang M, Zhou C
Nucleic acids research 2021 Dec 2;49(21):12306-12319
Nucleic acids research 2021 Dec 2;49(21):12306-12319
Evaluating the Effect of Lenvatinib on Sorafenib-Resistant Hepatocellular Carcinoma Cells.
Shi T, Iwama H, Fujita K, Kobara H, Nishiyama N, Fujihara S, Goda Y, Yoneyama H, Morishita A, Tani J, Yamada M, Nakahara M, Takuma K, Masaki T
International journal of molecular sciences 2021 Dec 2;22(23)
International journal of molecular sciences 2021 Dec 2;22(23)
A distributed residue network permits conformational binding specificity in a conserved family of actin remodelers.
Hwang T, Parker SS, Hill SM, Ilunga MW, Grant RA, Mouneimne G, Keating AE
eLife 2021 Dec 2;10
eLife 2021 Dec 2;10
Probiotic Bacillus cereus Alleviates Dextran Sulfate Sodium-Induced Colitis in Mice through Improvement of the Intestinal Barrier Function, Anti-Inflammation, and Gut Microbiota Modulation.
Sheng K, Xu Y, Kong X, Wang J, Zha X, Wang Y
Journal of agricultural and food chemistry 2021 Dec 15;69(49):14810-14823
Journal of agricultural and food chemistry 2021 Dec 15;69(49):14810-14823
Tangeretin maintains antioxidant activity by reducing CUL3 mediated NRF2 ubiquitination.
Wang Y, Jin R, Chen J, Cao J, Xiao J, Li X, Sun C
Food chemistry 2021 Dec 15;365:130470
Food chemistry 2021 Dec 15;365:130470
Carnosol alleviates nonalcoholic fatty liver disease by inhibiting mitochondrial dysfunction and apoptosis through targeting of PRDX3.
Geng Y, Wang Y, Sun R, Kang X, Zhao H, Zhu M, Sun Y, Hu Y, Wang Z, Tian X, Zhao Y, Yao J
Toxicology and applied pharmacology 2021 Dec 1;432:115758
Toxicology and applied pharmacology 2021 Dec 1;432:115758
Involvement of endoplasmic reticulum stress-activated PERK-eIF2α-ATF4 signaling pathway in T-2 toxin-induced apoptosis of porcine renal epithelial cells.
Liu X, Wang Z, Wang X, Yan X, He Q, Liu S, Ye M, Li X, Yuan Z, Wu J, Yi J, Wen L, Li R
Toxicology and applied pharmacology 2021 Dec 1;432:115753
Toxicology and applied pharmacology 2021 Dec 1;432:115753
PAX5-activated lncRNA ARRDC1-AS1 accelerates the autophagy and progression of DLBCL through sponging miR-2355-5p to regulate ATG5.
Xu H, Yu X, Yang Z, Song Q, Cheng S, He Z, Dai L
Life sciences 2021 Dec 1;286:119932
Life sciences 2021 Dec 1;286:119932
Ketamine enhances novel object recognition memory reconsolidation via the BDNF/TrkB pathway in mice.
Fan JF, Tang ZH, Wang SY, Lei S, Zhang B, Tian SW
Physiology & behavior 2021 Dec 1;242:113626
Physiology & behavior 2021 Dec 1;242:113626
Role of the hippo signaling pathway in the extracellular matrix degradation of chondrocytes induced by fluoride exposure.
Yu FF, Zuo J, Fu X, Gao MH, Sun L, Yu SY, Li Z, Zhou GY, Ba Y
Ecotoxicology and environmental safety 2021 Dec 1;225:112796
Ecotoxicology and environmental safety 2021 Dec 1;225:112796
Cypermethrin triggers YY1-mediated testosterone biosynthesis suppression.
Liu C, Qu J, Wu M, Huang X, Li L
Ecotoxicology and environmental safety 2021 Dec 1;225:112792
Ecotoxicology and environmental safety 2021 Dec 1;225:112792
Quercetin reverses chronic unpredictable mild stress-induced depression-like behavior in vivo by involving nuclear factor-E2-related factor 2.
Guan Y, Wang J, Wu X, Song L, Wang Y, Gong M, Li B
Brain research 2021 Dec 1;1772:147661
Brain research 2021 Dec 1;1772:147661
ATF6-mediated unfolded protein response facilitates AAV2 transduction by releasing the suppression of AAV receptor on ER stress.
Cui M, Zhao Q, Wang J, Si Y, Cheng S, Ding W
Journal of virology 2021 Dec 1;:JVI0110321
Journal of virology 2021 Dec 1;:JVI0110321
Metformin alleviates hydrogen peroxide-induced inflammation and oxidative stress via inhibiting P2X7R signaling in spinal cord tissue cells neurons.
Wang G, Chen S, Shao Z, Li Y, Wang W, Mao L, Li J, Mei X
Canadian journal of physiology and pharmacology 2021 Aug;99(8):768-774
Canadian journal of physiology and pharmacology 2021 Aug;99(8):768-774
AKR1C3 decreased CML sensitivity to Imatinib in bone marrow microenvironment via dysregulation of miR-379-5p.
Pan D, Yang W, Zeng Y, Li W, Wang K, Zhao L, Li J, Ye Y, Guo Q
Cellular signalling 2021 Aug;84:110038
Cellular signalling 2021 Aug;84:110038
Heat shock protein 90 inhibitor ameliorates pancreatic fibrosis by degradation of transforming growth factor-β receptor.
Peng YF, Lin H, Liu DC, Zhu XY, Huang N, Wei YX, Li L
Cellular signalling 2021 Aug;84:110001
Cellular signalling 2021 Aug;84:110001
Microglial Calhm2 regulates neuroinflammation and contributes to Alzheimer's disease pathology.
Cheng J, Dong Y, Ma J, Pan R, Liao Y, Kong X, Li X, Li S, Chen P, Wang L, Yu Y, Yuan Z
Science advances 2021 Aug;7(35)
Science advances 2021 Aug;7(35)
Rapid generation of maternal mutants via oocyte transgenic expression of CRISPR-Cas9 and sgRNAs in zebrafish.
Zhang C, Lu T, Zhang Y, Li J, Tarique I, Wen F, Chen A, Wang J, Zhang Z, Zhang Y, Shi DL, Shao M
Science advances 2021 Aug;7(32)
Science advances 2021 Aug;7(32)
The intervention of intestinal Wnt/β-catenin pathway alters inflammation and disease severity of CIA.
Tan W, Qiu Y, Chen N, Gao J, Liang J, Liu Y, Zhao D
Immunologic research 2021 Aug;69(4):323-333
Immunologic research 2021 Aug;69(4):323-333
Milk Polar Lipids Supplementation to Obese Rats During Pregnancy and Lactation Benefited Skeletal Outcomes of Male Offspring.
Han L, Du M, Ren F, Mao X
Molecular nutrition & food research 2021 Aug;65(15):e2001208
Molecular nutrition & food research 2021 Aug;65(15):e2001208
H. pylori infection induces CXCL8 expression and promotes gastric cancer progress through downregulating KLF4.
Liu Z, Wu X, Tian Y, Zhang W, Qiao S, Xu W, Liu Y, Wang S
Molecular carcinogenesis 2021 Aug;60(8):524-537
Molecular carcinogenesis 2021 Aug;60(8):524-537
Exosomal miR-193b-5p as a regulator of LPS-induced inflammation in dairy cow mammary epithelial cells.
Xu H, Zhang T, Hu X, Xie Y, Wu R, Lian S, Wang J
In vitro cellular & developmental biology. Animal 2021 Aug;57(7):695-703
In vitro cellular & developmental biology. Animal 2021 Aug;57(7):695-703
Circadian misalignment promotes vascular smooth muscle cell apoptosis via defective autophagy.
Guo Z, Yu B, Li X, Yang X, Wang C, Fan L
Journal of molecular histology 2021 Aug;52(4):799-808
Journal of molecular histology 2021 Aug;52(4):799-808
Progranulin promotes osteogenic differentiation of periodontal membrane stem cells in both inflammatory and non-inflammatory conditions.
Yu M, Sun L, Ba P, Li L, Chen J, Sun Q
The Journal of international medical research 2021 Aug;49(8):3000605211032508
The Journal of international medical research 2021 Aug;49(8):3000605211032508
Lipocalin-2: a role in hepatic gluconeogenesis via AMP-activated protein kinase (AMPK).
Sun WX, Lou K, Chen LJ, Liu SD, Pang SG
Journal of endocrinological investigation 2021 Aug;44(8):1753-1765
Journal of endocrinological investigation 2021 Aug;44(8):1753-1765
Hepatoprotective effects of loach (Misgurnus anguillicaudatus) lyophilized powder on dimethylnitrosamine-induced liver fibrosis in rats.
Zhang Q, Shang MM, Ling QF, Wu XP, Liu CY
Archives of pharmacal research 2021 Aug;44(8):1-12
Archives of pharmacal research 2021 Aug;44(8):1-12
Chicoric acid attenuates hyperglycemia-induced endothelial dysfunction through AMPK-dependent inhibition of oxidative/nitrative stresses.
Ma X, Zhang J, Wu Z, Wang X
Journal of receptor and signal transduction research 2021 Aug;41(4):378-392
Journal of receptor and signal transduction research 2021 Aug;41(4):378-392
W436, a novel SMART derivative, exhibits anti-hepatocarcinoma activity by inducing apoptosis and G2/M cell cycle arrest in vitro and in vivo and induces protective autophagy.
Man S, Wu Z, Sun R, Guan Q, Li Z, Zuo D, Zhang W, Wu Y
Journal of biochemical and molecular toxicology 2021 Aug;35(8):e22831
Journal of biochemical and molecular toxicology 2021 Aug;35(8):e22831
Immunization with recombinant Erns-LTB fusion protein elicits protective immune responses against bovine viral diarrhea virus.
Wang SH, Yang GH, Nie JW, Wang J, Wang YX, Du MZ, Guo L, Yang RJ, Zhu YH
Veterinary microbiology 2021 Aug;259:109084
Veterinary microbiology 2021 Aug;259:109084
Downregulation of SUN2 promotes metastasis of colon cancer by activating BDNF/TrkB signalling by interacting with SIRT1.
Liu L, Li SW, Yuan W, Tang J, Sang Y
The Journal of pathology 2021 Aug;254(5):531-542
The Journal of pathology 2021 Aug;254(5):531-542
Procyanidin B2 alleviates liver injury caused by cold stimulation through Sonic hedgehog signalling and autophagy.
Ma L, Li C, Lian S, Xu B, Lv H, Liu Y, Lu J, Ji H, Li S, Guo J, Yang H
Journal of cellular and molecular medicine 2021 Aug;25(16):8015-8027
Journal of cellular and molecular medicine 2021 Aug;25(16):8015-8027
LncRNA MAYA promotes iron overload and hepatocyte senescence through inhibition of YAP in non-alcoholic fatty liver disease.
Yuan P, Qi X, Song A, Ma M, Zhang X, Lu C, Bian M, Lian N, He J, Zheng S, Jin H
Journal of cellular and molecular medicine 2021 Aug;25(15):7354-7366
Journal of cellular and molecular medicine 2021 Aug;25(15):7354-7366
CircPLCE1 facilitates the malignant progression of colorectal cancer by repressing the SRSF2-dependent PLCE1 pre-RNA splicing.
Chen Z, Chen H, Yang L, Li X, Wang Z
Journal of cellular and molecular medicine 2021 Aug;25(15):7244-7256
Journal of cellular and molecular medicine 2021 Aug;25(15):7244-7256
Fisetin mitigates hepatic ischemia-reperfusion injury by regulating GSK3β/AMPK/NLRP3 inflammasome pathway.
Pu JL, Huang ZT, Luo YH, Mou T, Li TT, Li ZT, Wei XF, Wu ZJ
Hepatobiliary & pancreatic diseases international : HBPD INT 2021 Aug;20(4):352-360
Hepatobiliary & pancreatic diseases international : HBPD INT 2021 Aug;20(4):352-360
DDIT3/CHOP promotes autophagy in chondrocytes via SIRT1-AKT pathway.
Yang C, Xu X, Dong X, Yang B, Dong W, Luo Y, Liu X, Wu Y, Wang J
Biochimica et biophysica acta. Molecular cell research 2021 Aug;1868(9):119074
Biochimica et biophysica acta. Molecular cell research 2021 Aug;1868(9):119074
Targeting P2RX1 alleviates renal ischemia/reperfusion injury by preserving mitochondrial dynamics.
Zhuang S, Xia S, Huang P, Wu J, Qu J, Chen R, Sun N, Li D, Wu H, Zhang M, Zhang J, Yuan X, Wang X
Pharmacological research 2021 Aug;170:105712
Pharmacological research 2021 Aug;170:105712
Ferroptosis inducer erastin sensitizes NSCLC cells to celastrol through activation of the ROS-mitochondrial fission-mitophagy axis.
Liu M, Fan Y, Li D, Han B, Meng Y, Chen F, Liu T, Song Z, Han Y, Huang L, Chang Y, Cao P, Nakai A, Tan K
Molecular oncology 2021 Aug;15(8):2084-2105
Molecular oncology 2021 Aug;15(8):2084-2105
Momordin Ic induces G0/1 phase arrest and apoptosis in colon cancer cells by suppressing SENP1/c-MYC signaling pathway.
Xianjun F, Xirui X, Jie T, Huiwen M, Shaojun Z, Qiaoyun L, Yunxin L, Xuqun S
Journal of pharmacological sciences 2021 Aug;146(4):249-258
Journal of pharmacological sciences 2021 Aug;146(4):249-258
The active ingredients and mechanisms of Longchai Jiangxue Formula in treating PV, based on UPLC/Q-TOF-MS/MS, systematic pharmacology, and molecular biology validation.
Ming J, Liu W, Wu H, Li Y, Yang E, Wang Z, Xiao H, Quan R, Hu X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Aug;140:111767
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Aug;140:111767
Systematic investigation of the pharmacological mechanism for renal protection by the leaves of Eucommia ulmoides Oliver using UPLC-Q-TOF/MS combined with network pharmacology analysis.
Huang Q, Zhang F, Liu S, Jiang Y, Ouyang D
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Aug;140:111735
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Aug;140:111735
Grouper TRAF5 exerts negative regulation on antiviral immune response against iridovirus.
Sun M, Wu S, Zhang X, Zhang L, Kang S, Qin Q, Wei J
Fish & shellfish immunology 2021 Aug;115:7-13
Fish & shellfish immunology 2021 Aug;115:7-13
Bone morphogenetic protein-7 inhibits endothelial-to-mesenchymal transition in primary human umbilical vein endothelial cells and mouse model of systemic sclerosis via Akt/mTOR/p70S6K pathway.
Shen C, Jiang Y, Li Q, Liu C, Hu F, Li M
Journal of dermatological science 2021 Aug;103(2):82-92
Journal of dermatological science 2021 Aug;103(2):82-92
Melatonin mediates monochromatic light-induced expression of somatostatin in the hypothalamus and pituitary of chicks.
Qin X, Liu X, Yan X, Long M, Wang Z, Dong Y, Chen Y, Cao J
Poultry science 2021 Aug;100(8):101285
Poultry science 2021 Aug;100(8):101285
Suramin attenuates intervertebral disc degeneration by inhibiting NF-κB signalling pathway.
Liu ZM, Lu CC, Shen PC, Chou SH, Shih CL, Chen JC, Tien YC
Bone & joint research 2021 Aug;10(8):498-513
Bone & joint research 2021 Aug;10(8):498-513
Extract of Cynomorium songaricum ameliorates mitochondrial ultrastructure impairments and dysfunction in two different in vitro models of Alzheimer's disease.
Cheng D, Su L, Wang X, Li X, Li L, Hu M, Lu Y
BMC complementary medicine and therapies 2021 Aug 9;21(1):206
BMC complementary medicine and therapies 2021 Aug 9;21(1):206
Metformin Is a Pyridoxal-5'-phosphate (PLP)-Competitive Inhibitor of SHMT2.
Tramonti A, Cuyàs E, Encinar JA, Pietzke M, Paone A, Verdura S, Arbusà A, Martin-Castillo B, Giardina G, Joven J, Vazquez A, Contestabile R, Cutruzzolà F, Menendez JA
Cancers 2021 Aug 9;13(16)
Cancers 2021 Aug 9;13(16)
TRIM28 SUMOylates and stabilizes NLRP3 to facilitate inflammasome activation.
Qin Y, Li Q, Liang W, Yan R, Tong L, Jia M, Zhao C, Zhao W
Nature communications 2021 Aug 9;12(1):4794
Nature communications 2021 Aug 9;12(1):4794
Association of CASC18/miR-20a-3p/TGFB2 ceRNA axis with occult lymph node metastasis in tongue squamous cell carcinoma.
Zhou B, Zhou Y, Liu Y, Zhang H, Mao H, Peng M, Xu A, Li Z, Wang H, Tan H, Ren H, Zhou X, Long Y
Molecular medicine (Cambridge, Mass.) 2021 Aug 6;27(1):85
Molecular medicine (Cambridge, Mass.) 2021 Aug 6;27(1):85
DEAD-box helicase 27 enhances stem cell-like properties with poor prognosis in breast cancer.
Li S, Ma J, Zheng A, Song X, Chen S, Jin F
Journal of translational medicine 2021 Aug 6;19(1):334
Journal of translational medicine 2021 Aug 6;19(1):334
METTL3 regulates PM2.5-induced cell injury by targeting OSGIN1 in human airway epithelial cells.
Yuan Q, Zhu H, Liu H, Wang M, Chu H, Zhang Z
Journal of hazardous materials 2021 Aug 5;415:125573
Journal of hazardous materials 2021 Aug 5;415:125573
Mammalian target of rapamycin signaling pathway is involved in synaptic plasticity of the spinal dorsal horn and neuropathic pain in rats by regulating autophagy.
Hu J, Chen X, Cheng J, Kong F, Xia H, Wu J
Neuroreport 2021 Aug 4;32(11):925-935
Neuroreport 2021 Aug 4;32(11):925-935
circBTBD7 Promotes Immature Porcine Sertoli Cell Growth through Modulating miR-24-3p/MAPK7 Axis to Inactivate p38 MAPK Signaling Pathway.
Bian Q, Chen B, Weng B, Chu D, Tang X, Yan S, Yin Y, Ran M
International journal of molecular sciences 2021 Aug 30;22(17)
International journal of molecular sciences 2021 Aug 30;22(17)
Targeting Amino Acid Metabolic Reprogramming via L-Type Amino Acid Transporter 1 (LAT1) for Endocrine-Resistant Breast Cancer.
Shindo H, Harada-Shoji N, Ebata A, Sato M, Soga T, Miyashita M, Tada H, Kawai M, Kosaka S, Onuki K, Usami S, Furumoto S, Hayashi S, Abe T, Suzuki T, Ishida T, Sasano H
Cancers 2021 Aug 30;13(17)
Cancers 2021 Aug 30;13(17)
The COL-4A1 polypeptide destroy endothelial cells through the TGF-β/PI3K/AKT pathway.
Li T, Ling Z, Xie K, Wang Y, Miao Z, Ji X, Li J, Hou W, Tang Q, Yuan X, Li N, Li C, Ding H
Scientific reports 2021 Aug 3;11(1):15761
Scientific reports 2021 Aug 3;11(1):15761
Protection of pancreatic β-cell by phosphocreatine through mitochondrial improvement via the regulation of dual AKT/IRS-1/GSK-3β and STAT3/Cyp-D signaling pathways.
Wang H, Ai J, Shopit A, Niu M, Ahmed N, Tesfaldet T, Tang Z, Li X, Jamalat Y, Chu P, Peng J, Ma X, Qaed E, Han G, Zhang W, Wang J, Tang Z
Cell biology and toxicology 2021 Aug 28;
Cell biology and toxicology 2021 Aug 28;
CCT5 interacts with cyclin D1 promoting lung adenocarcinoma cell migration and invasion.
Meng Y, Yang L, Wei X, Luo H, Hu Y, Tao X, He J, Zheng X, Xu Q, Luo K, Yu G, Luo Q
Biochemical and biophysical research communications 2021 Aug 27;567:222-229
Biochemical and biophysical research communications 2021 Aug 27;567:222-229
Association of T2285C polymorphism in PARP1 gene coding region with its expression, activity and NSCLC risk along with prognosis.
Wang Y, Xia XB, Tang HZ, Cai JR, Shi XK, Ji HX, Yan XN, Xu T
Mutagenesis 2021 Aug 27;36(4):281-293
Mutagenesis 2021 Aug 27;36(4):281-293
Glyceraldehyde-3-Phosphate Dehydrogenase Restricted in Cytoplasmic Location by Viral GP5 Facilitates Porcine Reproductive and Respiratory Syndrome Virus Replication via Its Glycolytic Activity.
Liu X, Liu X, Bai J, Gao Y, Song Z, Nauwynck H, Wang X, Yang Y, Jiang P
Journal of virology 2021 Aug 25;95(18):e0021021
Journal of virology 2021 Aug 25;95(18):e0021021
Hepatoprotective effect of anemoside B4 against sepsis-induced acute liver injury through modulating the mTOR/p70S6K-mediated autophagy.
Pei L, He L
Chemico-biological interactions 2021 Aug 25;345:109534
Chemico-biological interactions 2021 Aug 25;345:109534
Ten-eleven translocation 1 mediated-DNA hydroxymethylation is required for myelination and remyelination in the mouse brain.
Zhang M, Wang J, Zhang K, Lu G, Liu Y, Ren K, Wang W, Xin D, Xu L, Mao H, Xing J, Gao X, Jin W, Berry K, Mikoshiba K, Wu S, Lu QR, Zhao X
Nature communications 2021 Aug 24;12(1):5091
Nature communications 2021 Aug 24;12(1):5091
Osthole inhibits the migration and invasion of highly metastatic breast cancer cells by suppressing ITGα3/ITGβ5 signaling.
Chen YQ, Song HY, Zhou ZY, Ma J, Luo ZY, Zhou Y, Wang JY, Liu S, Han XH
Acta pharmacologica Sinica 2021 Aug 23;
Acta pharmacologica Sinica 2021 Aug 23;
Circular RNA CircEYA3 induces energy production to promote pancreatic ductal adenocarcinoma progression through the miR-1294/c-Myc axis.
Rong Z, Shi S, Tan Z, Xu J, Meng Q, Hua J, Liu J, Zhang B, Wang W, Yu X, Liang C
Molecular cancer 2021 Aug 21;20(1):106
Molecular cancer 2021 Aug 21;20(1):106
HIF-1α-activated TM4SF1-AS1 promotes the proliferation, migration, and invasion of hepatocellular carcinoma cells by enhancing TM4SF1 expression.
Zeng Z, Shi Z, Liu Y, Zhao J, Lu Q, Guo J, Liu X, Huang D, Xu Q
Biochemical and biophysical research communications 2021 Aug 20;566:80-86
Biochemical and biophysical research communications 2021 Aug 20;566:80-86
Advanced oxidation protein products impair autophagic flux in macrophage by inducing lysosomal dysfunction via activation of PI3K-Akt-mTOR pathway in Crohn's disease.
Liao Y, Xu J, Qin B, Shi J, Qin C, Xie F, Ou S, Tang J, Wang W, Wu F, Bai L
Free radical biology & medicine 2021 Aug 20;172:33-47
Free radical biology & medicine 2021 Aug 20;172:33-47
MicroRNA-138-1-3p sensitizes sorafenib to hepatocellular carcinoma by targeting PAK5 mediated β-catenin/ABCB1 signaling pathway.
Li TT, Mou J, Pan YJ, Huo FC, Du WQ, Liang J, Wang Y, Zhang LS, Pei DS
Journal of biomedical science 2021 Aug 2;28(1):56
Journal of biomedical science 2021 Aug 2;28(1):56
Polysaccharides from Ulva prolifera O.F. Müller inhibit cell proliferation via activating MAPK signaling in A549 and H1650 cells.
Yang JJ, Wang YH, Yin J, Leng H, Shen SD
Food & function 2021 Aug 2;12(15):6915-6924
Food & function 2021 Aug 2;12(15):6915-6924
Antitumor Effects of Astaxanthin on Esophageal Squamous Cell Carcinoma by up-Regulation of PPARγ.
Cui L, Li Z, Xu F, Tian Y, Chen T, Li J, Guo Y, Lyu Q
Nutrition and cancer 2021 Aug 2;:1-12
Nutrition and cancer 2021 Aug 2;:1-12
IL-22 Downregulates Peptidylarginine Deiminase-1 in Human Keratinocytes: Adding Another Piece to the IL-22 Puzzle in Epidermal Barrier Formation.
Padhi A, Srivastava A, Ramesh A, Ehrström M, Simon M, Sonkoly E, Eidsmo L, Bergman P, Lysell J
The Journal of investigative dermatology 2021 Aug 2;
The Journal of investigative dermatology 2021 Aug 2;
Ceruloplasmin correlates with immune infiltration and serves as a prognostic biomarker in breast cancer.
Chen F, Han B, Meng Y, Han Y, Liu B, Zhang B, Chang Y, Cao P, Fan Y, Tan K
Aging 2021 Aug 19;13(16):20438-20467
Aging 2021 Aug 19;13(16):20438-20467
Silibinin Suppresses Tumor Cell-Intrinsic Resistance to Nintedanib and Enhances Its Clinical Activity in Lung Cancer.
Bosch-Barrera J, Verdura S, Ruffinelli JC, Carcereny E, Sais E, Cuyàs E, Palmero R, Lopez-Bonet E, Hernández-Martínez A, Oliveras G, Buxó M, Izquierdo A, Morán T, Nadal E, Menendez JA
Cancers 2021 Aug 19;13(16)
Cancers 2021 Aug 19;13(16)
Serum DJ-1 Is a Biomarker of Colorectal Cancer and DJ-1 Activates Mitophagy to Promote Colorectal Cancer Progression.
Chen WT, Yang HB, Ke TW, Liao WL, Hung SY
Cancers 2021 Aug 18;13(16)
Cancers 2021 Aug 18;13(16)
Large-scale and high-resolution mass spectrometry-based proteomics profiling defines molecular subtypes of esophageal cancer for therapeutic targeting.
Liu W, Xie L, He YH, Wu ZY, Liu LX, Bai XF, Deng DX, Xu XE, Liao LD, Lin W, Heng JH, Xu X, Peng L, Huang QF, Li CY, Zhang ZD, Wang W, Zhang GR, Gao X, Wang SH, Li CQ, Xu LY, Liu W, Li EM
Nature communications 2021 Aug 16;12(1):4961
Nature communications 2021 Aug 16;12(1):4961
In vitro assessment of a synergistic combination of gemcitabine and zebularine in pancreatic cancer cells.
Patki M, Saraswat A, Bhutkar S, Dukhande V, Patel K
Experimental cell research 2021 Aug 15;405(2):112660
Experimental cell research 2021 Aug 15;405(2):112660
Microtubule associated protein 4 (MAP4) phosphorylation reduces cardiac microvascular density through NLRP3-related pyroptosis.
Feng YH, Li LF, Zhang Q, Zhang JH, Huang Y, Lv YL, Jia JZ, Zhang D, Hu JY, Huang YS
Cell death discovery 2021 Aug 12;7(1):213
Cell death discovery 2021 Aug 12;7(1):213
KAT2A-mediated AR translocation into nucleus promotes abiraterone-resistance in castration-resistant prostate cancer.
Lu D, Song Y, Yu Y, Wang D, Liu B, Chen L, Li X, Li Y, Cheng L, Lv F, Zhang P, Xing Y
Cell death & disease 2021 Aug 12;12(8):787
Cell death & disease 2021 Aug 12;12(8):787
Metformin attenuates renal tubulointerstitial fibrosis via upgrading autophagy in the early stage of diabetic nephropathy.
Wang F, Sun H, Zuo B, Shi K, Zhang X, Zhang C, Sun D
Scientific reports 2021 Aug 11;11(1):16362
Scientific reports 2021 Aug 11;11(1):16362
Nervous Necrosis Virus Coat Protein Mediates Host Translation Shutoff through Nuclear Translocalization and Degradation of Polyadenylate Binding Protein.
Cheng CA, Luo JM, Chiang MH, Fang KY, Li CH, Chen CW, Wang YS, Chang CY
Journal of virology 2021 Aug 10;95(17):e0236420
Journal of virology 2021 Aug 10;95(17):e0236420
Ophiocordyceps lanpingensis polysaccharides alleviate chronic kidney disease through MAPK/NF-κB pathway.
Zhou S, He Y, Zhang W, Xiong Y, Jiang L, Wang J, Cui X, Qu Y, Ge F
Journal of ethnopharmacology 2021 Aug 10;276:114189
Journal of ethnopharmacology 2021 Aug 10;276:114189
LncRNA LINC00680 promotes lung adenocarcinoma growth via binding to GATA6 and canceling GATA6-mediated suppression of SOX12 expression.
Sun X, Wang R, Tan M, Tian X, Meng J
Experimental cell research 2021 Aug 1;405(1):112653
Experimental cell research 2021 Aug 1;405(1):112653
Empagliflozin, a sodium glucose cotransporter-2 inhibitor, ameliorates peritoneal fibrosis via suppressing TGF-β/Smad signaling.
Shentu Y, Li Y, Xie S, Jiang H, Sun S, Lin R, Chen C, Bai Y, Zhang Y, Zheng C, Zhou Y
International immunopharmacology 2021 Apr;93:107374
International immunopharmacology 2021 Apr;93:107374
Ergosterol peroxide exhibits antiviral and immunomodulatory abilities against porcine deltacoronavirus (PDCoV) via suppression of NF-κB and p38/MAPK signaling pathways in vitro.
Duan C, Ge X, Wang J, Wei Z, Feng WH, Wang J
International immunopharmacology 2021 Apr;93:107317
International immunopharmacology 2021 Apr;93:107317
LncRNA ABCC6P1 promotes proliferation and migration of papillary thyroid cancer cells via Wnt/β-catenin signaling pathway.
Guan Y, Li Y, Yang QB, Yu J, Qiao H
Annals of translational medicine 2021 Apr;9(8):664
Annals of translational medicine 2021 Apr;9(8):664
Limonin induces apoptosis of HL-60 cells by inhibiting NQO1 activity.
Chen Y, Liang J, Liang X, Chen J, Wang Y, Cao J, Sun C, Ye J, Chen Q
Food science & nutrition 2021 Apr;9(4):1860-1869
Food science & nutrition 2021 Apr;9(4):1860-1869
Melatonin Ameliorates Lipopolysaccharide-Induced Microglial Inflammation via Triggering SIRT1/HMGB1 Signaling Axis.
Chibaatar E, Le K, Abdoulaye IA, Wu S, Guo Y
Journal of molecular neuroscience : MN 2021 Apr;71(4):691-701
Journal of molecular neuroscience : MN 2021 Apr;71(4):691-701
Pooled CRISPR screening identifies m6A as a positive regulator of macrophage activation.
Tong J, Wang X, Liu Y, Ren X, Wang A, Chen Z, Yao J, Mao K, Liu T, Meng FL, Pan W, Zou Q, Liu J, Zhou Y, Xia Q, Flavell RA, Zhu S, Li HB
Science advances 2021 Apr;7(18)
Science advances 2021 Apr;7(18)
Bio-inspired chiral self-assemblies promoted neuronal differentiation of retinal progenitor cells through activation of metabolic pathway.
Sun N, Dou X, Tang Z, Zhang D, Ni N, Wang J, Gao H, Ju Y, Dai X, Zhao C, Gu P, Ji J, Feng C
Bioactive materials 2021 Apr;6(4):990-997
Bioactive materials 2021 Apr;6(4):990-997
Perilipin 4 Protein: an Impending Target for Amyotrophic Lateral Sclerosis.
Zhu L, Hu F, Li C, Zhang C, Hang R, Xu R
Molecular neurobiology 2021 Apr;58(4):1723-1737
Molecular neurobiology 2021 Apr;58(4):1723-1737
Inhibition of soluble epoxide hydrolase (sEH) protects hippocampal neurons and reduces cognitive decline in type 2 diabetic mice.
Wu J, Fan Z, Zhao Y, Chen Q, Xiao Q
The European journal of neuroscience 2021 Apr;53(8):2532-2540
The European journal of neuroscience 2021 Apr;53(8):2532-2540
Expression of lncRNA CCAT2 in children with neuroblastoma and its effect on cancer cell growth.
Chen M, Zhao M, Hou Y, Zhu B
Molecular and cellular biochemistry 2021 Apr;476(4):1871-1879
Molecular and cellular biochemistry 2021 Apr;476(4):1871-1879
Induction of NUPR1 and AP‑1 contributes to the carcinogenic potential of nickel.
Murphy A, Roy N, Sun H, Jin C, Costa M
Oncology reports 2021 Apr;45(4)
Oncology reports 2021 Apr;45(4)
Anti-thrombotic activity of phenolic acids obtained from Salvia miltiorrhiza f. alba in TNF-α-stimulated endothelial cells via the NF-κB/JNK/p38 MAPK signaling pathway.
Zheng X, Liu H, Ma M, Ji J, Zhu F, Sun L
Archives of pharmacal research 2021 Apr;44(4):427-438
Archives of pharmacal research 2021 Apr;44(4):427-438
miR-182-5p and miR-96-5p Target PIAS1 and Mediate the Negative Feedback Regulatory Loop between PIAS1 and STAT3 in Endometrial Cancer.
Xiao Y, Huang W, Huang H, Wang L, Wang M, Zhang T, Fang X, Xia X
DNA and cell biology 2021 Apr;40(4):618-628
DNA and cell biology 2021 Apr;40(4):618-628
CRISPR/Cas9 library screening uncovered methylated PKP2 as a critical driver of lung cancer radioresistance by stabilizing β-catenin.
Cheng C, Pei X, Li SW, Yang J, Li C, Tang J, Hu K, Huang G, Min WP, Sang Y
Oncogene 2021 Apr;40(16):2842-2857
Oncogene 2021 Apr;40(16):2842-2857
The orphan nuclear receptor Nurr1 agonist amodiaquine mediates neuroprotective effects in 6-OHDA Parkinson's disease animal model by enhancing the phosphorylation of P38 mitogen-activated kinase but not PI3K/AKT signaling pathway.
Kambey PA, Chengcheng M, Xiaoxiao G, Abdulrahman AA, Kanwore K, Nadeem I, Jiao W, Gao D
Metabolic brain disease 2021 Apr;36(4):609-625
Metabolic brain disease 2021 Apr;36(4):609-625
Programmed cell death 4 modulates lysosomal function by inhibiting TFEB translation.
Chen X, Guan Y, Zhang Y, Jia Y, Li W, Guo C, Li Y, Wang X, Shi Y, Wang Q, Zhu F, Li Y, Zhang L
Cell death and differentiation 2021 Apr;28(4):1237-1250
Cell death and differentiation 2021 Apr;28(4):1237-1250
ARFGAP1 binds to classical swine fever virus NS5A protein and enhances CSFV replication in PK-15 cells.
Zhang L, Jin M, Song M, Liu S, Wang T, Guo K, Zhang Y
Veterinary microbiology 2021 Apr;255:109034
Veterinary microbiology 2021 Apr;255:109034
MARCH5 restores endothelial cell function against ischaemic/hypoxia injury via Akt/eNOS pathway.
Lei W, Li J, Li C, Chen L, Huang F, Xiao D, Zhang J, Zhao J, Li G, Qu T, Zhou H, Liao Y, Chen M
Journal of cellular and molecular medicine 2021 Apr;25(7):3182-3193
Journal of cellular and molecular medicine 2021 Apr;25(7):3182-3193
Method used to establish a large animal model of drug-induced acute kidney injury.
Wang SY, Zhang CY, Cai GY, Chen XM
Experimental biology and medicine (Maywood, N.J.) 2021 Apr;246(8):986-995
Experimental biology and medicine (Maywood, N.J.) 2021 Apr;246(8):986-995
Postnatal growth retardation is associated with deteriorated intestinal mucosal barrier function using a porcine model.
Qi M, Tan B, Wang J, Liao S, Li J, Cui Z, Shao Y, Ji P, Yin Y
Journal of cellular physiology 2021 Apr;236(4):2631-2648
Journal of cellular physiology 2021 Apr;236(4):2631-2648
[Effect of astragaloside IV on the expression of NOD-like receptor protein 3 inflammasome in neonatal rats with hypoxic-ischemic brain damage].
Li N, Mu YP, Liu CY, Wang Y, Li XF, Wang XW
Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 2021 Apr;23(4):402-409
Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 2021 Apr;23(4):402-409
LncIHAT Is Induced by Hypoxia-Inducible Factor 1 and Promotes Breast Cancer Progression.
Chen L, Bao L, Niu Y, Wang JE, Kumar A, Xing C, Wang Y, Luo W
Molecular cancer research : MCR 2021 Apr;19(4):678-687
Molecular cancer research : MCR 2021 Apr;19(4):678-687
Cigarette smoke extract amplifies NADPH oxidase-dependent ROS production to inactivate PTEN by oxidation in BEAS-2B cells.
Cai B, Liu M, Li J, Xu D, Li J
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Apr;150:112050
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Apr;150:112050
Low-dose naltrexone plays antineoplastic role in cervical cancer progression through suppressing PI3K/AKT/mTOR pathway.
Liu N, Yan L, Shan F, Wang X, Qu N, Handley MK, Ma M
Translational oncology 2021 Apr;14(4):101028
Translational oncology 2021 Apr;14(4):101028
The S100 calcium-binding protein A11 promotes hepatic steatosis through RAGE-mediated AKT-mTOR signaling.
Teng F, Jiang J, Zhang J, Yuan Y, Li K, Zhou B, Zhou X, Liu W, Zhang P, Liu D, Zheng M, Lu Y, Zhang H
Metabolism: clinical and experimental 2021 Apr;117:154725
Metabolism: clinical and experimental 2021 Apr;117:154725
Resveratrol Attenuates Meningitic Escherichia coli-Mediated Blood-Brain Barrier Disruption.
Yang R, Lv Y, Miao L, Zhang H, Qu X, Chen J, Xu B, Yang B, Fu J, Tan C, Chen H, Wang X
ACS infectious diseases 2021 Apr 9;7(4):777-789
ACS infectious diseases 2021 Apr 9;7(4):777-789
PolyQ-expanded proteins impair cellular proteostasis of ataxin-3 through sequestering the co-chaperone HSJ1 into aggregates.
Yue HW, Hong JY, Zhang SX, Jiang LL, Hu HY
Scientific reports 2021 Apr 9;11(1):7815
Scientific reports 2021 Apr 9;11(1):7815
Absence of TNF Leads to Alternative Activation in Peritoneal Macrophages in Experimental Listeria Monocytogenes Infection.
Li X, Chen C, Zhang L, Cheng X, Geng H, Ji Q, Li C, Chen H, Körner H, Liu X
Immunological investigations 2021 Apr 8;:1-18
Immunological investigations 2021 Apr 8;:1-18
Methylene blue prevents osteoarthritis progression and relieves pain in rats via upregulation of Nrf2/PRDX1.
Li JW, Wang RL, Xu J, Sun KY, Jiang HM, Sun ZY, Lv ZY, Xu XQ, Wu R, Guo H, Jiang Q, Shi DQ
Acta pharmacologica Sinica 2021 Apr 8;
Acta pharmacologica Sinica 2021 Apr 8;
N(6)-methyladenosine-binding protein YTHDF1 suppresses EBV replication and promotes EBV RNA decay.
Xia TL, Li X, Wang X, Zhu YJ, Zhang H, Cheng W, Chen ML, Ye Y, Li Y, Zhang A, Dai DL, Zhu QY, Yuan L, Zheng J, Huang H, Chen SQ, Xiao ZW, Wang HB, Roy G, Zhong Q, Lin D, Zeng YX, Wang J, Zhao B, Gewurz BE, Chen J, Zuo Z, Zeng MS
EMBO reports 2021 Apr 7;22(4):e50128
EMBO reports 2021 Apr 7;22(4):e50128
ASIC1 and ASIC3 mediate cellular senescence of human nucleus pulposus mesenchymal stem cells during intervertebral disc degeneration.
Ding J, Zhang R, Li H, Ji Q, Cheng X, Thorne RF, Hondermarck H, Liu X, Shen C
Aging 2021 Apr 6;13(7):10703-10723
Aging 2021 Apr 6;13(7):10703-10723
EGFR-ERK induced activation of GRHL1 promotes cell cycle progression by up-regulating cell cycle related genes in lung cancer.
He Y, Gan M, Wang Y, Huang T, Wang J, Han T, Yu B
Cell death & disease 2021 Apr 30;12(5):430
Cell death & disease 2021 Apr 30;12(5):430
Interleukin-17A mediates tobacco smoke-induced lung cancer epithelial-mesenchymal transition through transcriptional regulation of ΔNp63α on miR-19.
Xie C, Zhu J, Huang C, Yang X, Wang X, Meng Y, Geng S, Wu J, Shen H, Hu Z, Meng Z, Li X, Zhong C
Cell biology and toxicology 2021 Apr 3;
Cell biology and toxicology 2021 Apr 3;
miR-190 promotes malignant transformation and progression of human urothelial cells through CDKN1B/p27 inhibition.
Huang S, Hua X, Kuang M, Zhu J, Mu H, Tian Z, Zheng X, Xie Q
Cancer cell international 2021 Apr 29;21(1):241
Cancer cell international 2021 Apr 29;21(1):241
Pterostilbene, a Dimethylether Analogue of Resveratrol, Possesses High Potency in the Prevention of Platelet Activation in Humans and the Reduction of Vascular Thrombosis in Mice.
Huang WC, Liu JC, Hsia CW, Fong TH, Hsia CH, Tran OT, Velusamy M, Yang CH, Sheu JR
Journal of agricultural and food chemistry 2021 Apr 28;69(16):4697-4707
Journal of agricultural and food chemistry 2021 Apr 28;69(16):4697-4707
Fludarabine Inhibits Infection of Zika Virus, SFTS Phlebovirus, and Enterovirus A71.
Gao C, Wen C, Li Z, Lin S, Gao S, Ding H, Zou P, Xing Z, Yu Y
Viruses 2021 Apr 27;13(5)
Viruses 2021 Apr 27;13(5)
Dynamic evolution of emphysema and airway remodeling in two mouse models of COPD.
Yang Y, Di T, Zhang Z, Liu J, Fu C, Wu Y, Bian T
BMC pulmonary medicine 2021 Apr 26;21(1):134
BMC pulmonary medicine 2021 Apr 26;21(1):134
Leukemia inhibitory factor regulates Schwann cell proliferation and migration and affects peripheral nerve regeneration.
Chen Q, Liu Q, Zhang Y, Li S, Yi S
Cell death & disease 2021 Apr 22;12(5):417
Cell death & disease 2021 Apr 22;12(5):417
Circ11103 Interacts with miR-128/PPARGC1A to Regulate Milk Fat Metabolism in Dairy Cows.
Chen Z, Lu Q, Liang Y, Cui X, Wang X, Mao Y, Yang Z
Journal of agricultural and food chemistry 2021 Apr 21;69(15):4490-4500
Journal of agricultural and food chemistry 2021 Apr 21;69(15):4490-4500
H2O2 enhances the anticancer activity of TMPyP4 by ROS-mediated mitochondrial dysfunction and DNA damage.
Chen J, Jin X, Shen Z, Mei Y, Zhu J, Zhang X, Liang G, Zheng X
Medical oncology (Northwood, London, England) 2021 Apr 21;38(6):59
Medical oncology (Northwood, London, England) 2021 Apr 21;38(6):59
Buprenorphine alters microglia and astrocytes acutely following diffuse traumatic brain injury.
Ryu J, Stone P, Lee S, Payne B, Gorse K, Lafrenaye A
Scientific reports 2021 Apr 21;11(1):8620
Scientific reports 2021 Apr 21;11(1):8620
CK2 Activity Mediates the Aggressive Molecular Signature of Glioblastoma Multiforme by Inducing Nerve/Glial Antigen (NG)2 Expression.
Schmitt BM, Boewe AS, Götz C, Philipp SE, Urbschat S, Oertel J, Menger MD, Laschke MW, Ampofo E
Cancers 2021 Apr 2;13(7)
Cancers 2021 Apr 2;13(7)
Identification of a mesenchymal-related signature associated with clinical prognosis in glioma.
Zhang Z, Chen J, Huo X, Zong G, Huang K, Cheng M, Sun L, Yue X, Bian E, Zhao B
Aging 2021 Apr 19;13(9):12431-12455
Aging 2021 Apr 19;13(9):12431-12455
Btk knockout attenuates the liver inflammation in STZ-induced diabetic mice by suppressing NLRP3 inflammasome activation.
Li Y, Zhao J, Wu Y, Xia L
Biochemical and biophysical research communications 2021 Apr 16;549:75-82
Biochemical and biophysical research communications 2021 Apr 16;549:75-82
An IgD-Fc-Ig fusion protein restrains the activation of T and B cells by inhibiting IgD-IgDR-Lck signaling in rheumatoid arthritis.
Hu XX, Zhang AJ, Pan WW, Xin QL, Chen JY, Zhang LL, Chang Y, Wu YJ, Wei W
Acta pharmacologica Sinica 2021 Apr 16;
Acta pharmacologica Sinica 2021 Apr 16;
Differential Expression of CB1 Cannabinoid Receptor and Cannabinoid Receptor Interacting Protein 1a in Labor.
Kozakiewicz ML, Zhang J, Leone-Kabler S, Yamaleyeva LM, McDonald AG, Brost BC, Howlett AC
Cannabis and cannabinoid research 2021 Apr 16;
Cannabis and cannabinoid research 2021 Apr 16;
Chemoproteomics-enabled discovery of covalent RNF114-based degraders that mimic natural product function.
Luo M, Spradlin JN, Boike L, Tong B, Brittain SM, McKenna JM, Tallarico JA, Schirle M, Maimone TJ, Nomura DK
Cell chemical biology 2021 Apr 15;28(4):559-566.e15
Cell chemical biology 2021 Apr 15;28(4):559-566.e15
Loss of Mitochondrial Protease CLPP Activates Type I IFN Responses through the Mitochondrial DNA-cGAS-STING Signaling Axis.
Torres-Odio S, Lei Y, Gispert S, Maletzko A, Key J, Menissy SS, Wittig I, Auburger G, West AP
Journal of immunology (Baltimore, Md. : 1950) 2021 Apr 15;206(8):1890-1900
Journal of immunology (Baltimore, Md. : 1950) 2021 Apr 15;206(8):1890-1900
AKR1B10 negatively regulates autophagy through reducing GAPDH upon glucose starvation in colon cancer.
Li W, Liu C, Huang Z, Shi L, Zhong C, Zhou W, Meng P, Li Z, Wang S, Luo F, Yan J, Wu T
Journal of cell science 2021 Apr 15;134(8)
Journal of cell science 2021 Apr 15;134(8)
Kisspeptin-10 Maintains the Activation of the mTOR Signaling Pathway by Inhibiting SIRT6 to Promote the Synthesis of Milk in Bovine Mammary Epithelial Cells.
Cao Y, Hu G, Zhang Q, Ma L, Wang J, Li W, Ge Y, Cheng J, Yang Z, Fu S, Liu J
Journal of agricultural and food chemistry 2021 Apr 14;69(14):4093-4100
Journal of agricultural and food chemistry 2021 Apr 14;69(14):4093-4100
AIF3 splicing switch triggers neurodegeneration.
Liu S, Zhou M, Ruan Z, Wang Y, Chang C, Sasaki M, Rajaram V, Lemoff A, Nambiar K, Wang JE, Hatanpaa KJ, Luo W, Dawson TM, Dawson VL, Wang Y
Molecular neurodegeneration 2021 Apr 14;16(1):25
Molecular neurodegeneration 2021 Apr 14;16(1):25
An Experimentally Induced Mutation in the UBA Domain of p62 Changes the Sensitivity of Cisplatin by Up-Regulating HK2 Localisation on the Mitochondria and Increasing Mitophagy in A2780 Ovarian Cancer Cells.
Yu S, Yan X, Tian R, Xu L, Zhao Y, Sun L, Su J
International journal of molecular sciences 2021 Apr 13;22(8)
International journal of molecular sciences 2021 Apr 13;22(8)
Nonsegmented Negative-Sense RNA Viruses Utilize N 6-Methyladenosine (m6A) as a Common Strategy To Evade Host Innate Immunity.
Lu M, Xue M, Wang HT, Kairis EL, Ahmad S, Wei J, Zhang Z, Liu Q, Zhang Y, Gao Y, Garcin D, Peeples ME, Sharma A, Hur S, He C, Li J
Journal of virology 2021 Apr 12;95(9)
Journal of virology 2021 Apr 12;95(9)
Kaempferol induces ROS-dependent apoptosis in pancreatic cancer cells via TGM2-mediated Akt/mTOR signaling.
Wang F, Wang L, Qu C, Chen L, Geng Y, Cheng C, Yu S, Wang D, Yang L, Meng Z, Chen Z
BMC cancer 2021 Apr 12;21(1):396
BMC cancer 2021 Apr 12;21(1):396
Effect of Shuangdan Mingmu capsule, a Chinese herbal formula, on oxidative stress-induced apoptosis of pericytes through PARP/GAPDH pathway.
Nie F, Yan J, Ling Y, Liu Z, Fu C, Li X, Qin Y
BMC complementary medicine and therapies 2021 Apr 10;21(1):118
BMC complementary medicine and therapies 2021 Apr 10;21(1):118
TET1 may contribute to hypoxia-induced epithelial to mesenchymal transition of endometrial epithelial cells in endometriosis.
Wu J, Li X, Huang H, Xia X, Zhang M, Fang X
PeerJ 2020;8:e9950
PeerJ 2020;8:e9950
Lycopene alleviates oxidative stress via the PI3K/Akt/Nrf2pathway in a cell model of Alzheimer's disease.
Fang Y, Ou S, Wu T, Zhou L, Tang H, Jiang M, Xu J, Guo K
PeerJ 2020;8:e9308
PeerJ 2020;8:e9308
Tethering of Telomeres to the Nuclear Envelope Is Mediated by SUN1-MAJIN and Possibly Promoted by SPDYA-CDK2 During Meiosis.
Wang G, Wu X, Zhou L, Gao S, Yun D, Liang A, Sun F
Frontiers in cell and developmental biology 2020;8:845
Frontiers in cell and developmental biology 2020;8:845
Enterohemorrhagic Escherichia coli Effector Protein EspF Interacts With Host Protein ANXA6 and Triggers Myosin Light Chain Kinase (MLCK)-Dependent Tight Junction Dysregulation.
Hua Y, Wu J, Fu M, Liu J, Li X, Zhang B, Zhao W, Wan C
Frontiers in cell and developmental biology 2020;8:613061
Frontiers in cell and developmental biology 2020;8:613061
Safrana l Prevents Prostate Cancer Recurrence by Blocking the Re-activation of Quiescent Cancer Cells via Downregulation of S-Phase Kinase-Associated Protein 2.
Jiang X, Li Y, Feng JL, Nik Nabil WN, Wu R, Lu Y, Liu H, Xi ZC, Xu HX
Frontiers in cell and developmental biology 2020;8:598620
Frontiers in cell and developmental biology 2020;8:598620
miR-7-5p Affects Brain Edema After Intracerebral Hemorrhage and Its Possible Mechanism.
Chen X, Deng S, Lei Q, He Q, Ren Y, Zhang Y, Nie J, Lu W
Frontiers in cell and developmental biology 2020;8:598020
Frontiers in cell and developmental biology 2020;8:598020
Amnion-Derived Mesenchymal Stem Cell Exosomes-Mediated Autophagy Promotes the Survival of Trophoblasts Under Hypoxia Through mTOR Pathway by the Downregulation of EZH2.
Chu Y, Chen W, Peng W, Liu Y, Xu L, Zuo J, Zhou J, Zhang Y, Zhang N, Li J, Liu L, Yao K, Gao G, Wang X, Han R, Liu C, Li Y, Zhou H, Huang Y, Ye Y
Frontiers in cell and developmental biology 2020;8:545852
Frontiers in cell and developmental biology 2020;8:545852
C2C12 Mouse Myoblasts Damage Induced by Oxidative Stress Is Alleviated by the Antioxidant Capacity of the Active Substance Phloretin.
Li J, Yang Q, Han L, Pan C, Lei C, Chen H, Lan X
Frontiers in cell and developmental biology 2020;8:541260
Frontiers in cell and developmental biology 2020;8:541260
Ferroptosis-Related Gene Signature Predicts Glioma Cell Death and Glioma Patient Progression.
Liu HJ, Hu HM, Li GZ, Zhang Y, Wu F, Liu X, Wang KY, Zhang CB, Jiang T
Frontiers in cell and developmental biology 2020;8:538
Frontiers in cell and developmental biology 2020;8:538
miR-205 Expression Elevated With EDS Treatment and Induced Leydig Cell Apoptosis by Targeting RAP2B via the PI3K/AKT Signaling Pathway.
Cui Y, Chen R, Ma L, Yang W, Chen M, Zhang Y, Yu S, Dong W, Zeng W, Lan X, Pan C
Frontiers in cell and developmental biology 2020;8:448
Frontiers in cell and developmental biology 2020;8:448
Ketamine ameliorates hypoxia-induced endothelial injury in human umbilical vein endothelial cells.
Zhou X, Liu J, Yang S, Su Y, Meng Z, Hu Y
Clinics (Sao Paulo, Brazil) 2020;75:e1865
Clinics (Sao Paulo, Brazil) 2020;75:e1865
Cdk5 Inhibitory Peptide Prevents Loss of Neurons and Alleviates Behavioral Changes in p25 Transgenic Mice.
Huang Y, Huang W, Huang Y, Song P, Zhang M, Zhang HT, Pan S, Hu Y
Journal of Alzheimer's disease : JAD 2020;74(4):1231-1242
Journal of Alzheimer's disease : JAD 2020;74(4):1231-1242
Maternal Methyl-Donor Micronutrient Supplementation During Pregnancy Promotes Skeletal Muscle Differentiation and Maturity in Newborn and Weaning Pigs.
He Q, Zou T, Chen J, Jian L, He J, Xia Y, Xie F, Wang Z, You J
Frontiers in nutrition 2020;7:609022
Frontiers in nutrition 2020;7:609022
Potential Role of SLC5A8 Expression in the Etiology of Subacute Ruminal Acidosis.
Zhao C, Bobe G, Wang Y, Zhang X, Zhao Z, Zhang S, Sun G, Yuan X, Li X, Liu G
Frontiers in veterinary science 2020;7:394
Frontiers in veterinary science 2020;7:394
miR-124-3p Suppresses the Invasiveness and Metastasis of Hepatocarcinoma Cells via Targeting CRKL.
Majid A, Wang J, Nawaz M, Abdul S, Ayesha M, Guo C, Liu Q, Liu S, Sun MZ
Frontiers in molecular biosciences 2020;7:223
Frontiers in molecular biosciences 2020;7:223
MicroRNA-362-3p Inhibits Migration and Invasion via Targeting BCAP31 in Cervical Cancer.
Yang S, Zhang X, Sun Y, Shi J, Jiang D, Wang J, Liu Y, Hu C, Pan J, Zheng L, Yang K
Frontiers in molecular biosciences 2020;7:107
Frontiers in molecular biosciences 2020;7:107
Metformin effectively treats Tsc1 deletion-caused kidney pathology by upregulating AMPK phosphorylation.
Fang Y, Li F, Qi C, Mao X, Wang F, Zhao Z, Chen JK, Zhang Z, Wu H
Cell death discovery 2020;6:52
Cell death discovery 2020;6:52
miR-143-3p inhibition promotes neuronal survival in an Alzheimer's disease cell model by targeting neuregulin-1.
Sun C, Jia N, Li R, Zhang Z, Zhong Y, Han K
Folia neuropathologica 2020;58(1):10-21
Folia neuropathologica 2020;58(1):10-21
Modulation of Wnt/β-catenin signaling in IL-17A-mediated macrophage polarization of RAW264.7 cells.
Yuan C, Yang D, Ma J, Yang J, Xue J, Song F, Liu X
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2020;53(8):e9488
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2020;53(8):e9488
Antrodia Cinnamomea Attenuates Non-Alcoholic Steatohepatitis by Suppressing NLRP3 Inflammasome Activation In Vitro and In Vivo.
Yen IC, Lin JC, Chen Y, Tu QW, Lee SY
The American journal of Chinese medicine 2020;48(8):1859-1874
The American journal of Chinese medicine 2020;48(8):1859-1874
Koumine Alleviates Lipopolysaccharide-Induced Intestinal Barrier Dysfunction in IPEC-J2 Cells by Regulating Nrf2/NF-
Wu J, Yang CL, Sha YK, Wu Y, Liu ZY, Yuan ZH, Sun ZL
The American journal of Chinese medicine 2020;48(1):127-142
The American journal of Chinese medicine 2020;48(1):127-142
Osthole Improves Cognitive Function of Vascular Dementia Rats: Reducing Aβ Deposition via Inhibition NLRP3 Inflammasome.
Liu Y, Chen X, Gong Q, Shi J, Li F
Biological & pharmaceutical bulletin 2020;43(9):1315-1323
Biological & pharmaceutical bulletin 2020;43(9):1315-1323
Dietary Baicalin Zinc Supplementation Alleviates Oxidative Stress and Enhances Nutrition Absorption in Deoxynivalenol Challenged Pigs.
Zha A, Cui Z, Qi M, Liao S, Chen L, Liao P, Tan B
Current drug metabolism 2020;21(8):614-625
Current drug metabolism 2020;21(8):614-625
Heme Oxygenase-1-Mediated Autophagy Protects against Oxidative Damage in Rat Nucleus Pulposus-Derived Mesenchymal Stem Cells.
Chen S, Liu S, Zhao L, Lin H, Ma K, Shao Z
Oxidative medicine and cellular longevity 2020;2020:9349762
Oxidative medicine and cellular longevity 2020;2020:9349762
Environmental Pollutant Benzo[a]pyrene Induces Recurrent Pregnancy Loss through Promoting Apoptosis and Suppressing Migration of Extravillous Trophoblast.
Ye Y, Jiang S, Zhang C, Cheng Y, Zhong H, Du T, Xu W, Azziz R, Zhang H, Zhao X
BioMed research international 2020;2020:8983494
BioMed research international 2020;2020:8983494
Disease Mutation Study Identifies Critical Residues for Phosphatidylserine Flippase ATP11A.
Sun K, Tian W, Li X, Liu W, Yang Y, Zhu X
BioMed research international 2020;2020:7342817
BioMed research international 2020;2020:7342817
Rhein Suppresses Neuroinflammation via Multiple Signaling Pathways in LPS-Stimulated BV2 Microglia Cells.
Zheng P, Tian X, Zhang W, Yang Z, Zhou J, Zheng J, Cui H, Tang T, Luo J, Wang Y
Evidence-based complementary and alternative medicine : eCAM 2020;2020:7210627
Evidence-based complementary and alternative medicine : eCAM 2020;2020:7210627
Hydrogen Gas Attenuates Hypoxic-Ischemic Brain Injury via Regulation of the MAPK/HO-1/PGC-1a Pathway in Neonatal Rats.
Wang P, Zhao M, Chen Z, Wu G, Fujino M, Zhang C, Zhou W, Zhao M, Hirano SI, Li XK, Zhao L
Oxidative medicine and cellular longevity 2020;2020:6978784
Oxidative medicine and cellular longevity 2020;2020:6978784
Human Tissue Kallikrein 1 Improves Erectile Dysfunction of Streptozotocin-Induced Diabetic Rats by Inhibition of Excessive Oxidative Stress and Activation of the PI3K/AKT/eNOS Pathway.
Luan Y, Cui K, Tang Z, Ruan Y, Liu K, Wang T, Chen Z, Wang S, Liu J
Oxidative medicine and cellular longevity 2020;2020:6834236
Oxidative medicine and cellular longevity 2020;2020:6834236
Bergenin Attenuates Hepatic Fibrosis by Regulating Autophagy Mediated by the PPAR-γ/TGF-β Pathway.
Xia Y, Li J, Chen K, Feng J, Guo C
PPAR research 2020;2020:6694214
PPAR research 2020;2020:6694214
Hyperglycemia Induces Endoplasmic Reticulum Stress in Atrial Cardiomyocytes, and Mitofusin-2 Downregulation Prevents Mitochondrial Dysfunction and Subsequent Cell Death.
Yuan M, Gong M, Zhang Z, Meng L, Tse G, Zhao Y, Bao Q, Zhang Y, Yuan M, Liu X, Li G, Liu T
Oxidative medicine and cellular longevity 2020;2020:6569728
Oxidative medicine and cellular longevity 2020;2020:6569728
Mild Hypothermia Attenuates Hepatic Ischemia-Reperfusion Injury through Regulating the JAK2/STAT3-CPT1a-Dependent Fatty Acid β-Oxidation.
Wang W, Hu X, Xia Z, Liu Z, Zhong Z, Lu Z, Liu A, Ye S, Cao Q, Wang Y, Zhu F, Ye Q
Oxidative medicine and cellular longevity 2020;2020:5849794
Oxidative medicine and cellular longevity 2020;2020:5849794
Dexmedetomidine Attenuates Neurotoxicity in Developing Rats Induced by Sevoflurane through Upregulating BDNF-TrkB-CREB and Downregulating ProBDNF-P75NRT-RhoA Signaling Pathway.
Dong Y, Hong W, Tang Z, Gao Y, Wu X, Liu H
Mediators of inflammation 2020;2020:5458061
Mediators of inflammation 2020;2020:5458061
NLRC3 Delays the Progression of AD in APP/PS1 Mice via Inhibiting PI3K Activation.
Zha L, Yu Z, Fang J, Zhou L, Guo W, Zhou J
Oxidative medicine and cellular longevity 2020;2020:5328031
Oxidative medicine and cellular longevity 2020;2020:5328031
Qingjie Fuzheng Granule Inhibited the Migration and Invasion of Colorectal Cancer Cells by Regulating the lncRNA ANRIL/let-7a/TGF-β1/Smad Axis.
Zhang L, Liu J, Lin S, Tan J, Huang B, Lin J
Evidence-based complementary and alternative medicine : eCAM 2020;2020:5264651
Evidence-based complementary and alternative medicine : eCAM 2020;2020:5264651
The Nrf2/PGC1α Pathway Regulates Antioxidant and Proteasomal Activity to Alter Cisplatin Sensitivity in Ovarian Cancer.
Deng X, Lin N, Fu J, Xu L, Luo H, Jin Y, Liu Y, Sun L, Su J
Oxidative medicine and cellular longevity 2020;2020:4830418
Oxidative medicine and cellular longevity 2020;2020:4830418
Congrong Shujing Granule-Induced GRP78 Expression Reduced Endoplasmic Reticulum Stress and Neuronal Apoptosis in the Midbrain in a Parkinson's Disease Rat Model.
Xu Q, Yang S, Wu F, Lin Y, Zhong J, Tang L, Hu X, Cai J
Evidence-based complementary and alternative medicine : eCAM 2020;2020:4796236
Evidence-based complementary and alternative medicine : eCAM 2020;2020:4796236
LncRNA CAR10 Upregulates PDPK1 to Promote Cervical Cancer Development by Sponging miR-125b-5p.
Hu T, Zhang Q, Gao L
BioMed research international 2020;2020:4351671
BioMed research international 2020;2020:4351671
Fasting Induces Hepatocellular Carcinoma Cell Apoptosis by Inhibiting SET8 Expression.
Qi J, Chen X, Wu Q, Wang J, Zhang H, Mao A, Zhu M, Miao C
Oxidative medicine and cellular longevity 2020;2020:3985089
Oxidative medicine and cellular longevity 2020;2020:3985089
Tyrosine Kinase Receptors Axl and MerTK Mediate the Beneficial Effect of Electroacupuncture in a Cuprizone-Induced Demyelinating Model.
Zou Z, Sun J, Kang Z, Wang Y, Zhao H, Zhu K, Wang J
Evidence-based complementary and alternative medicine : eCAM 2020;2020:3205176
Evidence-based complementary and alternative medicine : eCAM 2020;2020:3205176
Gubenzhike Recipe Ameliorates Respiratory Mucosal Immunity in Mice with Chronic Obstructive Pulmonary Disease through Upregulation of the γδT Lymphocytes and KGF Levels.
Wang YQ, Liao Q, Tang SH, Cai Z, Zhang HC
Evidence-based complementary and alternative medicine : eCAM 2020;2020:3056797
Evidence-based complementary and alternative medicine : eCAM 2020;2020:3056797
Hypouricemic Effects of Extracts from Urtica hyperborea Jacq. ex Wedd. in Hyperuricemia Mice through XOD, URAT1, and OAT1.
Han S, Wei R, Han D, Zhu J, Luo W, Ao W, Zhong G
BioMed research international 2020;2020:2968135
BioMed research international 2020;2020:2968135
Gentiopicroside Ameliorates Oxidative Stress and Lipid Accumulation through Nuclear Factor Erythroid 2-Related Factor 2 Activation.
Jin M, Feng H, Wang Y, Yan S, Shen B, Li Z, Qin H, Wang Q, Li J, Liu G
Oxidative medicine and cellular longevity 2020;2020:2940746
Oxidative medicine and cellular longevity 2020;2020:2940746
N-Butanol Extract of Gastrodia elata Suppresses Inflammatory Responses in Lipopolysaccharide-Stimulated Macrophages and Complete Freund's Adjuvant- (CFA-) Induced Arthritis Rats via Inhibition of MAPK Signaling Pathway.
He P, Hu Y, Huang C, Wang X, Zhang H, Zhang X, Dai H, Wang R, Gao Y
Evidence-based complementary and alternative medicine : eCAM 2020;2020:1658618
Evidence-based complementary and alternative medicine : eCAM 2020;2020:1658618
Effect of Thymoquinone on Acute Kidney Injury Induced by Sepsis in BALB/c Mice.
Guo LP, Liu SX, Yang Q, Liu HY, Xu LL, Hao YH, Zhang XQ
BioMed research international 2020;2020:1594726
BioMed research international 2020;2020:1594726
HuR Affects Proliferation and Apoptosis of Chronic Lymphocytic Leukemia Cells via NF-κB Pathway.
Xiao K, Yang L, Gao X, An Y, Xie W, Jingquan G
BioMed research international 2020;2020:1481572
BioMed research international 2020;2020:1481572
Azelaic Acid Exerts Antileukemia Effects against Acute Myeloid Leukemia by Regulating the Prdxs/ROS Signaling Pathway.
Zhang D, Luo Z, Jin Y, Chen Y, Yang T, Yang Q, Wu B, Shang Y, Liu X, Wei Y, Zhou F
Oxidative medicine and cellular longevity 2020;2020:1295984
Oxidative medicine and cellular longevity 2020;2020:1295984
Melatonin Alleviates Neuroinflammation and Metabolic Disorder in DSS-Induced Depression Rats.
Lv WJ, Liu C, Yu LZ, Zhou JH, Li Y, Xiong Y, Guo A, Chao LM, Qu Q, Wei GW, Tang XG, Yin YL, Guo SN
Oxidative medicine and cellular longevity 2020;2020:1241894
Oxidative medicine and cellular longevity 2020;2020:1241894
Suppression of NLRP3 Inflammasome, Pyroptosis, and Cell Death by NIM811 in Rotenone-Exposed Cells as an in vitro Model of Parkinson's Disease.
Zhang M, He Q, Chen G, Li PA
Neuro-degenerative diseases 2020;20(2-3):73-83
Neuro-degenerative diseases 2020;20(2-3):73-83
MiR-1307-5p targeting TRAF3 upregulates the MAPK/NF-κB pathway and promotes lung adenocarcinoma proliferation.
Du X, Wang S, Liu X, He T, Lin X, Wu S, Wang D, Li J, Huang W, Yang H
Cancer cell international 2020;20:502
Cancer cell international 2020;20:502
XIST lost induces ovarian cancer stem cells to acquire taxol resistance via a KMT2C-dependent way.
Huang R, Zhu L, Zhang Y
Cancer cell international 2020;20:436
Cancer cell international 2020;20:436
TET1 promotes fatty acid oxidation and inhibits NAFLD progression by hydroxymethylation of PPARα promoter.
Wang J, Zhang Y, Zhuo Q, Tseng Y, Wang J, Ma Y, Zhang J, Liu J
Nutrition & metabolism 2020;17:46
Nutrition & metabolism 2020;17:46
Integrin α1 promotes tumorigenicity and progressive capacity of colorectal cancer.
Li H, Wang Y, Rong SK, Li L, Chen T, Fan YY, Wang YF, Yang CR, Yang C, Cho WC, Yang J
International journal of biological sciences 2020;16(5):815-826
International journal of biological sciences 2020;16(5):815-826
PFKP is transcriptionally repressed by BRCA1/ZBRK1 and predicts prognosis in breast cancer.
Yeerken D, Hong R, Wang Y, Gong Y, Liu R, Yang D, Li J, Fan J, Chen J, Zhang W, Zhan Q
PloS one 2020;15(5):e0233750
PloS one 2020;15(5):e0233750
Structure-function analyses of candidate small molecule RPN13 inhibitors with antitumor properties.
Anchoori RK, Tan M, Tseng SH, Peng S, Soong RS, Algethami A, Foran P, Das S, Wang C, Wang TL, Liang H, Hung CF, Roden RBS
PloS one 2020;15(1):e0227727
PloS one 2020;15(1):e0227727
Jia-Ji Electro-Acupuncture Improves Locomotor Function With Spinal Cord Injury by Regulation of Autophagy Flux and Inhibition of Necroptosis.
Hongna Y, Hongzhao T, Quan L, Delin F, Guijun L, Xiaolin L, Fulin G, Zhongren S
Frontiers in neuroscience 2020;14:616864
Frontiers in neuroscience 2020;14:616864
Hydrogen Sulfide Overproduction Is Involved in Acute Ischemic Cerebral Injury Under Hyperhomocysteinemia.
Ji Y, Li Y, Zhao Z, Li P, Xie Y
Frontiers in neuroscience 2020;14:582851
Frontiers in neuroscience 2020;14:582851
Olfactory Mucosa Mesenchymal Stem Cells Ameliorate Cerebral Ischemic/Reperfusion Injury Through Modulation of UBIAD1 Expression.
Liu J, Huang Y, He J, Zhuo Y, Chen W, Ge L, Duan D, Lu M, Hu Z
Frontiers in cellular neuroscience 2020;14:580206
Frontiers in cellular neuroscience 2020;14:580206
Differences in DNA Methylation Reprogramming Underlie the Sexual Dimorphism of Behavioral Disorder Caused by Prenatal Stress in Rats.
Lei L, Wu X, Gu H, Ji M, Yang J
Frontiers in neuroscience 2020;14:573107
Frontiers in neuroscience 2020;14:573107
iTRAQ-Based Quantitative Proteomic Analysis of Intestines in Murine Polymicrobial Sepsis with Hydrogen Gas Treatment.
Jiang Y, Bian Y, Lian N, Wang Y, Xie K, Qin C, Yu Y
Drug design, development and therapy 2020;14:4885-4900
Drug design, development and therapy 2020;14:4885-4900
Identification of a Novel c-Myc Inhibitor 7594-0037 by Structure-Based Virtual Screening and Investigation of Its Anti-Cancer Effect on Multiple Myeloma.
Yao R, Xie Y, Sun X, Zhang M, Zhou J, Liu L, Gao J, Xu K
Drug design, development and therapy 2020;14:3983-3993
Drug design, development and therapy 2020;14:3983-3993
The Potential Effects of Aliskiren on Atrial Remodeling Induced by Chronic Intermittent Hypoxia in Rats.
Miao S, Yang Y, Li R, Yin L, Zhang K, Cheng L, Xu X, Wang W, Zhao Z, Li G
Drug design, development and therapy 2020;14:3755-3764
Drug design, development and therapy 2020;14:3755-3764
Electro-Acupuncture Promotes the Differentiation of Endogenous Neural Stem Cells via Exosomal microRNA 146b After Ischemic Stroke.
Zhang S, Jin T, Wang L, Liu W, Zhang Y, Zheng Y, Lin Y, Yang M, He X, Lin H, Chen L, Tao J
Frontiers in cellular neuroscience 2020;14:223
Frontiers in cellular neuroscience 2020;14:223
Paeoniflorin Ameliorates Chronic Hypoxia/SU5416-Induced Pulmonary Arterial Hypertension by Inhibiting Endothelial-to-Mesenchymal Transition.
Yu M, Peng L, Liu P, Yang M, Zhou H, Ding Y, Wang J, Huang W, Tan Q, Wang Y, Xie W, Kong H, Wang H
Drug design, development and therapy 2020;14:1191-1202
Drug design, development and therapy 2020;14:1191-1202
The knockdown of the sepiapterin reductase gene suppresses the proliferation of breast cancer by inducing ROS-mediated apoptosis.
Zhang X, Chen Y, Wang K, Tang J, Chen Y, Jin G, Liu X
International journal of clinical and experimental pathology 2020;13(9):2228-2239
International journal of clinical and experimental pathology 2020;13(9):2228-2239
Chaetomugilin J Enhances Apoptosis in Human Ovarian Cancer A2780 Cells Induced by Cisplatin Through Inhibiting Pink1/Parkin Mediated Mitophagy.
Hu X, Wang J, Chai J, Yu X, Zhang Y, Feng Y, Qin J, Yu H
OncoTargets and therapy 2020;13:9967-9976
OncoTargets and therapy 2020;13:9967-9976
MicroRNA-623 Inhibits Epithelial-Mesenchymal Transition to Attenuate Glioma Proliferation by Targeting TRIM44.
Cui D, Wang K, Liu Y, Gao J, Cui J
OncoTargets and therapy 2020;13:9291-9303
OncoTargets and therapy 2020;13:9291-9303
Excessive Treadmill Training Enhances Brain-Specific MicroRNA-34a in the Mouse Hippocampus.
Xu L, Zheng YL, Yin X, Xu SJ, Tian D, Zhang CY, Wang S, Ma JZ
Frontiers in molecular neuroscience 2020;13:7
Frontiers in molecular neuroscience 2020;13:7
Chronic Intermittent Hypobaric Hypoxia Restores Hippocampus Function and Rescues Cognitive Impairments in Chronic Epileptic Rats via Wnt/β-catenin Signaling.
Sun C, Fu J, Qu Z, Jia L, Li D, Zhen J, Wang W
Frontiers in molecular neuroscience 2020;13:617143
Frontiers in molecular neuroscience 2020;13:617143
β-Elemene Enhances the Chemotherapeutic Effect of 5-Fluorouracil in Triple-Negative Breast Cancer via PI3K/AKT, RAF-MEK-ErK, and NF-κB Signaling Pathways.
Su P, Ahmad B, Zou K, Zou L
OncoTargets and therapy 2020;13:5207-5222
OncoTargets and therapy 2020;13:5207-5222
Elevated Levels of circRUNX1 in Colorectal Cancer Promote Cell Growth and Metastasis via miR-145-5p/IGF1 Signalling.
Chen ZL, Li XN, Ye CX, Chen HY, Wang ZJ
OncoTargets and therapy 2020;13:4035-4048
OncoTargets and therapy 2020;13:4035-4048
Microsatellite Instability-Related ACVR2A Mutations Partially Account for Decreased Lymph Node Metastasis in MSI-H Gastric Cancers.
Zhao L, Zhang J, Qu X, Yang Y, Gong Z, Yang Y, Wu Z, Guo W
OncoTargets and therapy 2020;13:3809-3821
OncoTargets and therapy 2020;13:3809-3821
Long Noncoding RNA NEAT1 Upregulates Survivin and Facilitates Gallbladder Cancer Progression by Sponging microRNA-335.
Yang F, Tang Z, Duan A, Yi B, Shen N, Bo Z, Yin L, Zhu B, Qiu Y, Li J
OncoTargets and therapy 2020;13:2357-2367
OncoTargets and therapy 2020;13:2357-2367
Alpha1-Antitrypsin in Urinary Extracellular Vesicles: A Potential Biomarker of Diabetic Kidney Disease Prior to Microalbuminuria.
Ning J, Xiang Z, Xiong C, Zhou Q, Wang X, Zou H
Diabetes, metabolic syndrome and obesity : targets and therapy 2020;13:2037-2048
Diabetes, metabolic syndrome and obesity : targets and therapy 2020;13:2037-2048
Empagliflozin Protects Against Proximal Renal Tubular Cell Injury Induced by High Glucose via Regulation of Hypoxia-Inducible Factor 1-Alpha.
Ndibalema AR, Kabuye D, Wen S, Li L, Li X, Fan Q
Diabetes, metabolic syndrome and obesity : targets and therapy 2020;13:1953-1967
Diabetes, metabolic syndrome and obesity : targets and therapy 2020;13:1953-1967
Simultaneous Inhibition of Ornithine Decarboxylase 1 and Pyruvate Kinase M2 Exerts Synergistic Effects Against Hepatocellular Carcinoma Cells.
Zeng Z, Lan J, Lei S, Yang Y, He Z, Xue Y, Chen T
OncoTargets and therapy 2020;13:11697-11709
OncoTargets and therapy 2020;13:11697-11709
MiR-935/HIF1α Feedback Loop Inhibits the Proliferation and Invasiveness of Glioma.
Huang G, Chen J, Liu J, Zhang X, Duan H, Fang Q
OncoTargets and therapy 2020;13:10817-10828
OncoTargets and therapy 2020;13:10817-10828
SNHG9 was upregulated in NSCLC and associated with DDP-resistance and poor prognosis of NSCLC patients.
Wang R, Chen C, Kang W, Meng G
American journal of translational research 2020;12(8):4456-4466
American journal of translational research 2020;12(8):4456-4466
Brequinar inhibits enterovirus replication by targeting biosynthesis pathway of pyrimidines.
Fu H, Zhang Z, Dai Y, Liu S, Fu E
American journal of translational research 2020;12(12):8247-8255
American journal of translational research 2020;12(12):8247-8255
A New Rat Model of Chronic Cerebral Hypoperfusion Resulting in Early-Stage Vascular Cognitive Impairment.
Wang J, Yang C, Wang H, Li D, Li T, Sun Y, Zhao M, Ma J, Hua W, Yang Z
Frontiers in aging neuroscience 2020;12:86
Frontiers in aging neuroscience 2020;12:86
Overexpression of IGFBP5 Enhances Radiosensitivity Through PI3K-AKT Pathway in Prostate Cancer.
Chen X, Yu Q, Pan H, Li P, Wang X, Fu S
Cancer management and research 2020;12:5409-5418
Cancer management and research 2020;12:5409-5418
Long Noncoding RNA LINC00261 Reduces Proliferation and Migration of Breast Cancer Cells via the NME1-EMT Pathway.
Guo G, Dai S, Chen Q
Cancer management and research 2020;12:3081-3089
Cancer management and research 2020;12:3081-3089
Resatorvid Relieves Breast Cancer Complicated with Depression by Inactivating Hippocampal Microglia Through TLR4/NF-κB/NLRP3 Signaling Pathway.
Luo W, Han Y, Meng P, Yang Q, Zhao H, Ling J, Wang Y
Cancer management and research 2020;12:13003-13014
Cancer management and research 2020;12:13003-13014
The lncRNA BCYRN1 Functions as an Oncogene in Human Glioma by Downregulating miR-125a-5p in vitro.
Yu W, Xiang D, Jia H, He X, Sheng J, Long Y, Zhu S, Wang K, Liu Q
Cancer management and research 2020;12:1151-1161
Cancer management and research 2020;12:1151-1161
Pyruvate dehydrogenase kinase 1 interferes with glucose metabolism reprogramming and mitochondrial quality control to aggravate stress damage in cancer.
Deng X, Wang Q, Cheng M, Chen Y, Yan X, Guo R, Sun L, Li Y, Liu Y
Journal of Cancer 2020;11(4):962-973
Journal of Cancer 2020;11(4):962-973
Long Noncoding RNA DSCAM-AS1 Facilitates Colorectal Cancer Cell Proliferation and Migration via miR-137/Notch1 Axis.
Xu J, Wu G, Zhao Y, Han Y, Zhang S, Li C, Zhang J
Journal of Cancer 2020;11(22):6623-6632
Journal of Cancer 2020;11(22):6623-6632
Arsenic trioxide (ATO) induced degradation of Cyclin D1 sensitized PD-1/PD-L1 checkpoint inhibitor in oral and esophageal squamous cell carcinoma.
Zhu G, Li X, Li J, Zhou W, Chen Z, Fan Y, Jiang Y, Zhao Y, Sun G, Mao W
Journal of Cancer 2020;11(22):6516-6529
Journal of Cancer 2020;11(22):6516-6529
Translocator Protein 18 kDa (TSPO) Deficiency Inhibits Microglial Activation and Impairs Mitochondrial Function.
Yao R, Pan R, Shang C, Li X, Cheng J, Xu J, Li Y
Frontiers in pharmacology 2020;11:986
Frontiers in pharmacology 2020;11:986
Mitochondrial Iron Overload-Mediated Inhibition of Nrf2-HO-1/GPX4 Assisted ALI-Induced Nephrotoxicity.
Deng HF, Yue LX, Wang NN, Zhou YQ, Zhou W, Liu X, Ni YH, Huang CS, Qiu LZ, Liu H, Tan HL, Tang XL, Wang YG, Ma ZC, Gao Y
Frontiers in pharmacology 2020;11:624529
Frontiers in pharmacology 2020;11:624529
Histone Deacetylase SIRT1 Mediates C5b-9-Induced Cell Cycle in Oligodendrocytes.
Tatomir A, Rao G, Boodhoo D, Vlaicu SI, Beltrand A, Anselmo F, Rus V, Rus H
Frontiers in immunology 2020;11:619
Frontiers in immunology 2020;11:619
Oleoylethanolamide Protects Against Acute Liver Injury by Regulating Nrf-2/HO-1 and NLRP3 Pathways in Mice.
Hu J, Zhu Z, Ying H, Yao J, Ma H, Li L, Zhao Y
Frontiers in pharmacology 2020;11:605065
Frontiers in pharmacology 2020;11:605065
A Mechanism of Action Study on Danggui Sini Decoction to Discover Its Therapeutic Effect on Gastric Cancer.
Pan B, Wang Y, Wu C, Jia J, Huang C, Fang S, Liu L
Frontiers in pharmacology 2020;11:592903
Frontiers in pharmacology 2020;11:592903
JAK2V617F Mutation Promoted IL-6 Production and Glycolysis via Mediating PKM1 Stabilization in Macrophages.
Li R, Sun N, Chen X, Li X, Zhao J, Cheng W, Hua H, Fukatsu M, Mori H, Takahashi H, Ohkawara H, Fukami M, Okamoto M, Hamazaki Y, Zheng K, Yang J, Ikezoe T
Frontiers in immunology 2020;11:589048
Frontiers in immunology 2020;11:589048
Bu-Shen-Huo-Xue Decoction Ameliorates Diabetic Nephropathy by Inhibiting Rac1/PAK1/p38MAPK Signaling Pathway in High-Fat Diet/Streptozotocin-Induced Diabetic Mice.
Wang W, Long H, Huang W, Zhang T, Xie L, Chen C, Liu J, Xiong D, Hu W
Frontiers in pharmacology 2020;11:587663
Frontiers in pharmacology 2020;11:587663
miR-222 Suppresses Immature Porcine Sertoli Cell Growth by Targeting the GRB10 Gene Through Inactivating the PI3K/AKT Signaling Pathway.
Luo H, Peng F, Weng B, Tang X, Chen Y, Yang A, Chen B, Ran M
Frontiers in genetics 2020;11:581593
Frontiers in genetics 2020;11:581593
Bu-Yin-Qian-Zheng Formula Ameliorates MPP+-Induced Mitochondrial Dysfunction in Parkinson's Disease via Parkin.
Ma HJ, Gai C, Chai Y, Feng WD, Cheng CC, Zhang JK, Zhang YX, Yang LP, Guo ZY, Gao YS, Sun HM
Frontiers in pharmacology 2020;11:577017
Frontiers in pharmacology 2020;11:577017
Molecular and Immune Characteristics for Lung Adenocarcinoma Patients With ERLIN2 Overexpression.
Liu Y, Xie P, Jiang D, Liu J, Zhang J, Bian T, Shi J
Frontiers in immunology 2020;11:568440
Frontiers in immunology 2020;11:568440
microRNA-630 Regulates Underglycosylated IgA1 Production in the Tonsils by Targeting TLR4 in IgA Nephropathy.
Liu C, Ye MY, Yan WZ, Peng XF, He LY, Peng YM
Frontiers in immunology 2020;11:563699
Frontiers in immunology 2020;11:563699
Metabolomics Deciphers Potential Targets of Xuefu Zhuyu Decoction Against Traumatic Brain Injury in Rat.
Li T, Hu E, Li P, Yang Z, Wu Y, Ding R, Zhu X, Tang T, Wang Y
Frontiers in pharmacology 2020;11:559618
Frontiers in pharmacology 2020;11:559618
Susceptibility to Hyperglycemia in Rats With Stress-Induced Depressive-Like Behavior: Involvement of IL-6 Mediated Glucose Homeostasis Signaling.
Li X, Qiu W, Li N, Da X, Ma Q, Hou Y, Wang T, Song M, Chen J
Frontiers in psychiatry 2020;11:557
Frontiers in psychiatry 2020;11:557
PKM2-c-Myc-Survivin Cascade Regulates the Cell Proliferation, Migration, and Tamoxifen Resistance in Breast Cancer.
Yu P, Li AX, Chen XS, Tian M, Wang HY, Wang XL, Zhang Y, Wang KS, Cheng Y
Frontiers in pharmacology 2020;11:550469
Frontiers in pharmacology 2020;11:550469
Effects of Xiaoyaosan on Depressive-Like Behaviors in Rats With Chronic Unpredictable Mild Stress Through HPA Axis Induced Astrocytic Activities.
Song M, Zhang J, Li X, Liu Y, Wang T, Yan Z, Chen J
Frontiers in psychiatry 2020;11:545823
Frontiers in psychiatry 2020;11:545823
Lian Hua Qing Wen Capsules, a Potent Epithelial Protector in Acute Lung Injury Model, Block Proapoptotic Communication Between Macrophages, and Alveolar Epithelial Cells.
Li Q, Ran Q, Sun L, Yin J, Luo T, Liu L, Zhao Z, Yang Q, Li Y, Chen Y, Weng X, Wang Y, Cai W, Zhu X
Frontiers in pharmacology 2020;11:522729
Frontiers in pharmacology 2020;11:522729
ARP-1 Regulates the Transcriptional Activity of the Aromatase Gene in the Mouse Brain.
Honda SI, Harada N
Frontiers in endocrinology 2020;11:306
Frontiers in endocrinology 2020;11:306
Scutellarein inhibits BLM-mediated pulmonary fibrosis by affecting fibroblast differentiation, proliferation, and apoptosis.
Miao K, Pan T, Mou Y, Zhang L, Xiong W, Xu Y, Yu J, Wang Y
Therapeutic advances in chronic disease 2020;11:2040622320940185
Therapeutic advances in chronic disease 2020;11:2040622320940185
MicroRNA-34a Inhibition Alleviates Lung Injury in Cecal Ligation and Puncture Induced Septic Mice.
Chen S, Ding R, Hu Z, Yin X, Xiao F, Zhang W, Yan S, Lv C
Frontiers in immunology 2020;11:1829
Frontiers in immunology 2020;11:1829
PPARγ as an E3 Ubiquitin-Ligase Impedes Phosphate-Stat6 Stability and Promotes Prostaglandins E2-Mediated Inhibition of IgE Production in Asthma.
Wu J, Wang Y, Zhou Y, Wang Y, Sun X, Zhao Y, Guan Y, Zhang Y, Wang W
Frontiers in immunology 2020;11:1224
Frontiers in immunology 2020;11:1224
Schisandrin B Inhibits Osteoclastogenesis and Protects Against Ovariectomy-Induced Bone Loss.
Wang J, Fang Z, Song C, Kang H, Guo Q, Dong Y, Zhang Y, Peng R, Guan H, Li F
Frontiers in pharmacology 2020;11:1175
Frontiers in pharmacology 2020;11:1175
Toddalolactone Protects Lipopolysaccharide-Induced Sepsis and Attenuates Lipopolysaccharide-Induced Inflammatory Response by Modulating HMGB1-NF-κB Translocation.
Ni J, Zhao Y, Su J, Liu Z, Fang S, Li L, Deng J, Fan G
Frontiers in pharmacology 2020;11:109
Frontiers in pharmacology 2020;11:109
MiR-10a-5p-Mediated Syndecan 1 Suppression Restricts Porcine Hemagglutinating Encephalomyelitis Virus Replication.
Hu S, Li Z, Lan Y, Guan J, Zhao K, Chu D, Fan G, Guo Y, Gao F, He W
Frontiers in microbiology 2020;11:105
Frontiers in microbiology 2020;11:105
Eye Drops of Metformin Prevents Fibrosis After Glaucoma Filtration Surgery in Rats via Activating AMPK/Nrf2 Signaling Pathway.
Li X, Leng Y, Jiang Q, Wang Z, Luo P, Zhang C, Chen L, Wang Y, Wang H, Yue X, Shen C, Zhou Y, Shi C, Xie L
Frontiers in pharmacology 2020;11:1038
Frontiers in pharmacology 2020;11:1038
CoenzymeQ10-Induced Activation of AMPK-YAP-OPA1 Pathway Alleviates Atherosclerosis by Improving Mitochondrial Function, Inhibiting Oxidative Stress and Promoting Energy Metabolism.
Xie T, Wang C, Jin Y, Meng Q, Liu Q, Wu J, Sun H
Frontiers in pharmacology 2020;11:1034
Frontiers in pharmacology 2020;11:1034
A miR-146a-5p/TRAF6/NF-kB p65 axis regulates pancreatic cancer chemoresistance: functional validation and clinical significance.
Meng Q, Liang C, Hua J, Zhang B, Liu J, Zhang Y, Wei M, Yu X, Xu J, Shi S
Theranostics 2020;10(9):3967-3979
Theranostics 2020;10(9):3967-3979
α1,6-Fucosyltransferase (FUT8) regulates the cancer-promoting capacity of cancer-associated fibroblasts (CAFs) by modifying EGFR core fucosylation (CF) in non-small cell lung cancer (NSCLC).
Li F, Zhao S, Cui Y, Guo T, Qiang J, Xie Q, Yu W, Guo W, Deng W, Gu C, Wu T
American journal of cancer research 2020;10(3):816-837
American journal of cancer research 2020;10(3):816-837
Cardio-renal Exosomes in Myocardial Infarction Serum Regulate Proangiogenic Paracrine Signaling in Adipose Mesenchymal Stem Cells.
Gao L, Mei S, Zhang S, Qin Q, Li H, Liao Y, Fan H, Liu Z, Zhu H
Theranostics 2020;10(3):1060-1073
Theranostics 2020;10(3):1060-1073
Theta-burst transcranial magnetic stimulation promotes stroke recovery by vascular protection and neovascularization.
Zong X, Li Y, Liu C, Qi W, Han D, Tucker L, Dong Y, Hu S, Yan X, Zhang Q
Theranostics 2020;10(26):12090-12110
Theranostics 2020;10(26):12090-12110
Graphene oxide improves postoperative cognitive dysfunction by maximally alleviating amyloid beta burden in mice.
Zhang J, Zhu S, Jin P, Huang Y, Dai Q, Zhu Q, Wei P, Yang Z, Zhang L, Liu H, Xu G, Chen L, Gu E, Zhang Y, Wen L, Liu X
Theranostics 2020;10(26):11908-11920
Theranostics 2020;10(26):11908-11920
Targeting BCL10 by small peptides for the treatment of B cell lymphoma.
Bao W, Sun C, Sun X, He M, Yu H, Yan W, Wen F, Zhang L, Yang C
Theranostics 2020;10(25):11622-11636
Theranostics 2020;10(25):11622-11636
Flubendazole elicits anti-cancer effects via targeting EVA1A-modulated autophagy and apoptosis in Triple-negative Breast Cancer.
Zhen Y, Zhao R, Wang M, Jiang X, Gao F, Fu L, Zhang L, Zhou XL
Theranostics 2020;10(18):8080-8097
Theranostics 2020;10(18):8080-8097
Protein acetylation derepresses Serotonin Synthesis to potentiate Pancreatic Beta-Cell Function through HDAC1-PKA-Tph1 signaling.
Zhang Y, Wang S, Zhang L, Zhou F, Zhu K, Zhu Q, Liu Q, Liu Y, Jiang L, Ning G, Bi Y, Zhou L, Wang X
Theranostics 2020;10(16):7351-7368
Theranostics 2020;10(16):7351-7368
Homozygous MESP1 knock-in reporter hESCs facilitated cardiovascular cell differentiation and myocardial infarction repair.
Wang L, Zhang F, Duan F, Huang R, Chen X, Ming J, Na J
Theranostics 2020;10(15):6898-6914
Theranostics 2020;10(15):6898-6914
Extracellular vesicle-mediated delivery of miR-101 inhibits lung metastasis in osteosarcoma.
Zhang K, Dong C, Chen M, Yang T, Wang X, Gao Y, Wang L, Wen Y, Chen G, Wang X, Yu X, Zhang Y, Wang P, Shang M, Han K, Zhou Y
Theranostics 2020;10(1):411-425
Theranostics 2020;10(1):411-425
Aberrant miR-1246 expression promotes radioresistance in non-small cell lung cancer: a potential prognostic biomarker and radiotherapy sensitization target.
Fan L, Wang J, Cao Q, Ding X, Li B
American journal of cancer research 2020;10(1):314-335
American journal of cancer research 2020;10(1):314-335
KLF13 suppresses the proliferation and growth of colorectal cancer cells through transcriptionally inhibiting HMGCS1-mediated cholesterol biosynthesis.
Yao W, Jiao Y, Zhou Y, Luo X
Cell & bioscience 2020;10:76
Cell & bioscience 2020;10:76
TIPE Regulates DcR3 Expression and Function by Activating the PI3K/AKT Signaling Pathway in CRC.
Zhong M, Qiu X, Liu Y, Yang Y, Gu L, Wang C, Chen H, Liu Z, Miao J, Zhuang G
Frontiers in oncology 2020;10:623048
Frontiers in oncology 2020;10:623048
Forkhead Box Q1 Is Critical to Angiogenesis and Macrophage Recruitment of Colorectal Cancer.
Tang H, Zheng J, Bai X, Yue KL, Liang JH, Li DY, Wang LP, Wang JL, Guo Q
Frontiers in oncology 2020;10:564298
Frontiers in oncology 2020;10:564298
Up-regulation of L Antigen Family Member 3 Associates With Aggressive Progression of Breast Cancer.
Dong X, Lv S, Gu D, Zhang X, Ye Z
Frontiers in oncology 2020;10:553628
Frontiers in oncology 2020;10:553628
A Natural Dietary Flavone Myricetin as an α-Hemolysin Inhibitor for Controlling Staphylococcus aureus Infection.
Wang T, Zhang P, Lv H, Deng X, Wang J
Frontiers in cellular and infection microbiology 2020;10:330
Frontiers in cellular and infection microbiology 2020;10:330
Steroid 5α-Reductase Type I Induces Cell Viability and Migration via Nuclear Factor-κB/Vascular Endothelial Growth Factor Signaling Pathway in Colorectal Cancer.
Wei R, Zhong S, Qiao L, Guo M, Shao M, Wang S, Jiang B, Yang Y, Gu C
Frontiers in oncology 2020;10:1501
Frontiers in oncology 2020;10:1501
The SIRT6-Autophagy-Warburg Effect Axis in Papillary Thyroid Cancer.
Yang Z, Huang R, Wei X, Yu W, Min Z, Ye M
Frontiers in oncology 2020;10:1265
Frontiers in oncology 2020;10:1265
Methylation-Induced Silencing of ALDH2 Facilitates Lung Adenocarcinoma Bone Metastasis by Activating the MAPK Pathway.
Yang M, Wang A, Li C, Sun J, Yi G, Cheng H, Liu X, Wang Z, Zhou Y, Yao G, Wang S, Liang R, Li B, Li D, Zhao H
Frontiers in oncology 2020;10:1141
Frontiers in oncology 2020;10:1141
Prognostic and Clinicopathological Significance of X-Box-Binding Protein 1 and N-Acetyltransferase 1 in Gallbladder Cancer.
Liu R, Wu Z, Zhang Y, Miao X, Zou Q, Yuan Y, Li D, Yang Z
Frontiers in oncology 2020;10:1124
Frontiers in oncology 2020;10:1124
NLRP6 contributes to inflammation and brain injury following intracerebral haemorrhage by activating autophagy.
Xiao H, Chen H, Jiang R, Zhang L, Wang L, Gan H, Jiang N, Zhao J, Zhai X, Liang P
Journal of molecular medicine (Berlin, Germany) 2020 Sep;98(9):1319-1331
Journal of molecular medicine (Berlin, Germany) 2020 Sep;98(9):1319-1331
Low-dose naltrexone inhibits the epithelial-mesenchymal transition of cervical cancer cells in vitro and effects indirectly on tumor-associated macrophages in vivo.
Liu N, Ma M, Qu N, Wang R, Chen H, Hu F, Gao S, Shan F
International immunopharmacology 2020 Sep;86:106718
International immunopharmacology 2020 Sep;86:106718
Increased regulatory T cells and eosinophils characterize atopic dermatitis-like graft-versus-host disease compared with lichen planus-like graft-versus-host disease.
Li K, Mu Z, Wen G, Zhao Y, Cong X, Zhang J
Journal of the American Academy of Dermatology 2020 Sep;83(3):824-831
Journal of the American Academy of Dermatology 2020 Sep;83(3):824-831
Sublethal Levels of Antibiotics Promote Bacterial Persistence in Epithelial Cells.
Liu X, Liu F, Ding S, Shen J, Zhu K
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2020 Sep;7(18):1900840
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2020 Sep;7(18):1900840
Mitochondrial Transplantation Attenuates Brain Dysfunction in Sepsis by Driving Microglial M2 Polarization.
Yan C, Ma Z, Ma H, Li Q, Zhai Q, Jiang T, Zhang Z, Wang Q
Molecular neurobiology 2020 Sep;57(9):3875-3890
Molecular neurobiology 2020 Sep;57(9):3875-3890
S-palmitoylation of swine interferon-inducible transmembrane protein is essential for its anti-JEV activity.
Xu Z, Li X, Xue J, Shen L, Zheng W, Yin S, Xu J
Virology 2020 Sep;548:82-92
Virology 2020 Sep;548:82-92
Deficiency of Grx1 leads to high sensitivity of HeLaS3 cells to oxidative stress via excessive accumulation of intracellular oxidants including ROS.
Zhao T, Zhang-Akiyama QM
Free radical research 2020 Sep;54(8-9):585-605
Free radical research 2020 Sep;54(8-9):585-605
Estrogen Exerts Neuroprotective Effects in Vascular Dementia Rats by Suppressing Autophagy and Activating the Wnt/β-Catenin Signaling Pathway.
Yang Y, Zhao L, Li N, Dai C, Yin N, Chu Z, Duan X, Niu X, Yan P, Lv P
Neurochemical research 2020 Sep;45(9):2100-2112
Neurochemical research 2020 Sep;45(9):2100-2112
MCC950 Inhibits NLRP3 Inflammasome and Alleviates Axonal Injures in Early Stages of Diffuse Axonal Injury in Rats.
Zhao J, Guo X, Wang B, Yang Z, Huang T, Guo D, Zhang M, Song J
Neurochemical research 2020 Sep;45(9):2020-2031
Neurochemical research 2020 Sep;45(9):2020-2031
A novel GNAS-mutated human induced pluripotent stem cell model for understanding GNAS-mutated tumors.
Watanabe K, Nakamura T, Onodera S, Saito A, Shibahara T, Azuma T
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2020 Sep;42(9):1010428320962588
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2020 Sep;42(9):1010428320962588
Visualization of translocator protein (18 kDa) (TSPO) in the retina of diabetic retinopathy rats using fluorine-18-DPA-714.
Zhou Y, Ou Y, Ju Z, Zhang X, Zheng L, Li J, Sun Y, Liu X
Annals of nuclear medicine 2020 Sep;34(9):675-681
Annals of nuclear medicine 2020 Sep;34(9):675-681
SRSF10 inhibits the polymerase activity and replication of avian influenza virus by regulating the alternative splicing of chicken ANP32A.
Fang A, Bi Z, Ye H, Yan L
Virus research 2020 Sep;286:198063
Virus research 2020 Sep;286:198063
The deubiquitylase USP2 maintains ErbB2 abundance via counteracting endocytic degradation and represents a therapeutic target in ErbB2-positive breast cancer.
Zhang J, Liu S, Li Q, Shi Y, Wu Y, Liu F, Wang S, Zaky MY, Yousuf W, Sun Q, Guo D, Wang T, Zhang Y, Wang Y, Li M, Liu H
Cell death and differentiation 2020 Sep;27(9):2710-2725
Cell death and differentiation 2020 Sep;27(9):2710-2725
RUNX3-dependent oxidative epithelial-to-mesenchymal transition in methamphetamine-induced chronic lung injury.
Shi L, Liu BY, Wang X, Zhu MJ, Chen L, Zhou MY, Gu YJ, Cheng L, Wang Y
Cell stress & chaperones 2020 Sep;25(5):793-802
Cell stress & chaperones 2020 Sep;25(5):793-802
ACE2 modulates glucose homeostasis through GABA signaling during metabolic stress.
Ma X, Gao F, Chen Q, Xuan X, Wang Y, Deng H, Yang F, Yuan L
The Journal of endocrinology 2020 Sep;246(3):223-236
The Journal of endocrinology 2020 Sep;246(3):223-236
Musashi2 promotes the progression of pancreatic cancer through a novel ISYNA1-p21/ZEB-1 pathway.
Zhou L, Sheng W, Jia C, Shi X, Cao R, Wang G, Lin Y, Zhu F, Dong Q, Dong M
Journal of cellular and molecular medicine 2020 Sep;24(18):10560-10572
Journal of cellular and molecular medicine 2020 Sep;24(18):10560-10572
Tacrolimus ameliorates tubulointerstitial inflammation in diabetic nephropathy via inhibiting the NFATc1/TRPC6 pathway.
Zhang S, Wang H, Liu Y, Yang W, Liu J, Han Y, Liu Y, Liu F, Sun L, Xiao L
Journal of cellular and molecular medicine 2020 Sep;24(17):9810-9824
Journal of cellular and molecular medicine 2020 Sep;24(17):9810-9824
Knockdown of endogenous RNF4 exacerbates ischaemia-induced cardiomyocyte apoptosis in mice.
Qiu F, Han Y, Shao X, Paulo P, Li W, Zhu M, Tang N, Guo S, Chen Y, Wu H, Zhao D, Liu Y, Chu W
Journal of cellular and molecular medicine 2020 Sep;24(17):9545-9559
Journal of cellular and molecular medicine 2020 Sep;24(17):9545-9559
Rosamultin Attenuates Acute Hypobaric Hypoxia-Induced Bone Injuries by Regulation of Sclerostin and Its Downstream Signals.
Wang XM, Liu H, Li JY, Wei JX, Li X, Zhang YL, Li LZ, Zhang XZ
High altitude medicine & biology 2020 Sep;21(3):273-286
High altitude medicine & biology 2020 Sep;21(3):273-286
Polyphyllin II inhibits human bladder cancer migration and invasion by regulating EMT-associated factors and MMPs.
Niu W, Xu L, Li J, Zhai Y, Sun Z, Shi W, Jiang Y, Ma C, Lin H, Guo Y, Liu Z
Oncology letters 2020 Sep;20(3):2928-2936
Oncology letters 2020 Sep;20(3):2928-2936
Sirtuin 3-mediated deacetylation of acyl-CoA synthetase family member 3 by protocatechuic acid attenuates non-alcoholic fatty liver disease.
Sun R, Kang X, Zhao Y, Wang Z, Wang R, Fu R, Li Y, Hu Y, Wang Z, Shan W, Zhou J, Tian X, Yao J
British journal of pharmacology 2020 Sep;177(18):4166-4180
British journal of pharmacology 2020 Sep;177(18):4166-4180
Methamphetamine induces GSDME-dependent cell death in hippocampal neuronal cells through the endoplasmic reticulum stress pathway.
Liu Y, Wen D, Gao J, Xie B, Yu H, Shen Q, Zhang J, Jing W, Cong B, Ma C
Brain research bulletin 2020 Sep;162:73-83
Brain research bulletin 2020 Sep;162:73-83
Inhibition of NK1R attenuates LPS-induced microglial inflammation and consequent death of PC12 cells.
Jiang W, Wang X, Wang W, Hua F, Zhang Z, Zhang Z, Xiang J, Yang X
Brain research bulletin 2020 Sep;162:115-124
Brain research bulletin 2020 Sep;162:115-124
NS5-V372A and NS5-H386Y variations are responsible for differences in interferon α/β induction and co-contribute to the replication advantage of Japanese encephalitis virus genotype I over genotype III in ducklings.
Li C, Di D, Huang H, Wang X, Xia Q, Ma X, Liu K, Li B, Shao D, Qiu Y, Li Z, Wei J, Ma Z
PLoS pathogens 2020 Sep;16(9):e1008773
PLoS pathogens 2020 Sep;16(9):e1008773
H63D variant of the homeostatic iron regulator (HFE) gene alters α-synuclein expression, aggregation, and toxicity.
Kim Y, Stahl MC, Huang X, Connor JR
Journal of neurochemistry 2020 Sep;155(2):177-190
Journal of neurochemistry 2020 Sep;155(2):177-190
Interleukin-18 levels in the hippocampus and behavior of adult rat offspring exposed to prenatal restraint stress during early and late pregnancy.
Chen MX, Liu Q, Cheng S, Lei L, Lin AJ, Wei R, K Hui TC, Li Q, Ao LJ, Sham PC
Neural regeneration research 2020 Sep;15(9):1748-1756
Neural regeneration research 2020 Sep;15(9):1748-1756
Control the fate of human umbilical cord mesenchymal stem cells with dual-enzymatically cross-linked gelatin hydrogels for potential applications in nerve regeneration.
Li J, Gao F, Ma S, Zhang Y, Zhang J, Guan F, Yao M
Journal of tissue engineering and regenerative medicine 2020 Sep;14(9):1261-1271
Journal of tissue engineering and regenerative medicine 2020 Sep;14(9):1261-1271
Duck IFIT5 differentially regulates Tembusu virus replication and inhibits virus-triggered innate immune response.
Wu X, Liu K, Jia R, Pan Y, Wang M, Chen S, Liu M, Zhu D, Zhao X, Wu Y, Yang Q, Zhang S, Huang J, Zhang L, Liu Y, Tian B, Pan L, Yu Y, Ur Rehman M, Yin Z, Jing B, Cheng A
Cytokine 2020 Sep;133:155161
Cytokine 2020 Sep;133:155161
The effect of monotropein on alleviating cisplatin-induced acute kidney injury by inhibiting oxidative damage, inflammation and apoptosis.
Zhang Y, Chen Y, Li B, Ding P, Jin D, Hou S, Cai X, Sheng X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Sep;129:110408
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Sep;129:110408
Dual PI3K/mTOR inhibitor PKI-402 suppresses the growth of ovarian cancer cells by degradation of Mcl-1 through autophagy.
Hu X, Xia M, Wang J, Yu H, Chai J, Zhang Z, Sun Y, Su J, Sun L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Sep;129:110397
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Sep;129:110397
SOCS3-deficient lung epithelial cells uptaking neutrophil-derived SOCS3 worsens lung influenza infection.
Li L, Wu H, Li Q, Chen J, Xu K, Xu J, Su X
Molecular immunology 2020 Sep;125:51-62
Molecular immunology 2020 Sep;125:51-62
The roles of grouper TANK in innate immune defense against iridovirus and nodavirus infections.
Wei J, Li C, Ou J, Zhang X, Liu Z, Qin Q
Fish & shellfish immunology 2020 Sep;104:506-516
Fish & shellfish immunology 2020 Sep;104:506-516
Zinc exerts its renal protection effect on arsenic-exposed common carp: A signaling network comprising Nrf2, NF-κB and MAPK pathways.
Wang Y, Zhao H, Liu Y, Nie X, Xing M
Fish & shellfish immunology 2020 Sep;104:383-390
Fish & shellfish immunology 2020 Sep;104:383-390
S-allyl-L-cysteine protects hepatocytes from indomethacin-induced apoptosis by attenuating endoplasmic reticulum stress.
Chen P, Chen C, Hu M, Cui R, Liu F, Yu H, Ren Y
FEBS open bio 2020 Sep;10(9):1900-1911
FEBS open bio 2020 Sep;10(9):1900-1911
HEATR1 promotes proliferation in gastric cancer in vitro and in vivo.
Zhao J, Zhu Y, Fu Q, Zhu Y, Zhao G
Acta biochimica et biophysica Sinica 2020 Sep 8;52(9):1030-1039
Acta biochimica et biophysica Sinica 2020 Sep 8;52(9):1030-1039
Autocrine INSL5 promotes tumor progression and glycolysis via activation of STAT5 signaling.
Li SB, Liu YY, Yuan L, Ji MF, Zhang A, Li HY, Tang LQ, Fang SG, Zhang H, Xing S, Li MZ, Zhong Q, Lin SJ, Liu WL, Huang P, Zeng YX, Zheng YM, Ling ZQ, Sui JH, Zeng MS
EMBO molecular medicine 2020 Sep 7;12(9):e12050
EMBO molecular medicine 2020 Sep 7;12(9):e12050
Circular RNA circREPS2 Acts as a Sponge of miR-558 to Suppress Gastric Cancer Progression by Regulating RUNX3/β-catenin Signaling.
Guo X, Dai X, Liu J, Cheng A, Qin C, Wang Z
Molecular therapy. Nucleic acids 2020 Sep 4;21:577-591
Molecular therapy. Nucleic acids 2020 Sep 4;21:577-591
The microRNA/TET3/REST axis is required for olfactory globose basal cell proliferation and male behavior.
Yang D, Wu X, Zhou Y, Wang W, Wang Z
EMBO reports 2020 Sep 3;21(9):e49431
EMBO reports 2020 Sep 3;21(9):e49431
Oxidative stress mediates the apoptosis and epigenetic modification of the Bcl-2 promoter via DNMT1 in a cigarette smoke-induced emphysema model.
Zeng H, Li T, He X, Cai S, Luo H, Chen P, Chen Y
Respiratory research 2020 Sep 3;21(1):229
Respiratory research 2020 Sep 3;21(1):229
Myricanol 5-fluorobenzyloxy ether regulation of survivin pathway inhibits human lung adenocarcinoma A549 cells growth in vitro.
Dai GH, Chen X, Ren ZM, Dai CJ, Tong YL, Chai KQ
BMC complementary medicine and therapies 2020 Sep 3;20(1):269
BMC complementary medicine and therapies 2020 Sep 3;20(1):269
Characterization of Low Molecular Weight Sulfate Ulva Polysaccharide and its Protective Effect against IBD in Mice.
Li Y, Ye H, Wang T, Wang P, Liu R, Li Y, Tian Y, Zhang J
Marine drugs 2020 Sep 29;18(10)
Marine drugs 2020 Sep 29;18(10)
NOD2/c-Jun NH2-Terminal Kinase Triggers Mycoplasma ovipneumoniae-Induced Macrophage Autophagy.
Luo H, Wu X, Xu Z, Hao X, Wang Y, Li M
Journal of bacteriology 2020 Sep 23;202(20)
Journal of bacteriology 2020 Sep 23;202(20)
L-Theanine affects intestinal mucosal immunity by regulating short-chain fatty acid metabolism under dietary fiber feeding.
Xu W, Lin L, Liu A, Zhang T, Zhang S, Li Y, Chen J, Gong Z, Liu Z, Xiao W
Food & function 2020 Sep 23;11(9):8369-8379
Food & function 2020 Sep 23;11(9):8369-8379
Astaxanthin attenuates oxidative stress and immune impairment in D-galactose-induced aging in rats by activating the Nrf2/Keap1 pathway and suppressing the NF-κB pathway.
Chen Z, Xiao J, Liu H, Yao K, Hou X, Cao Y, Liu X
Food & function 2020 Sep 23;11(9):8099-8111
Food & function 2020 Sep 23;11(9):8099-8111
Neural progenitor cell pyroptosis contributes to Zika virus-induced brain atrophy and represents a therapeutic target.
He Z, An S, Chen J, Zhang S, Tan C, Yu J, Ye H, Wu Y, Yuan J, Wu J, Zhu X, Li M
Proceedings of the National Academy of Sciences of the United States of America 2020 Sep 22;117(38):23869-23878
Proceedings of the National Academy of Sciences of the United States of America 2020 Sep 22;117(38):23869-23878
(+)-Clausenamide protects against drug-induced liver injury by inhibiting hepatocyte ferroptosis.
Wang M, Liu CY, Wang T, Yu HM, Ouyang SH, Wu YP, Gong HB, Ma XH, Jiao GL, Fu LL, Wu QS, Kurihara H, Li YF, Shen T, He RR
Cell death & disease 2020 Sep 19;11(9):781
Cell death & disease 2020 Sep 19;11(9):781
Overexpression of MicroRNA-9a-5p Ameliorates NLRP1 Inflammasome-mediated Ischemic Injury in Rats Following Ischemic Stroke.
Cao Y, Zhang H, Lu X, Wang J, Zhang X, Sun S, Bao Z, Tian W, Ning S, Wang L, Cui L
Neuroscience 2020 Sep 15;444:106-117
Neuroscience 2020 Sep 15;444:106-117
Inhibition of autophagy enhances timosaponin AIII-induced lung cancer cell apoptosis and anti-tumor effect in vitro and in vivo.
Liu J, Deng X, Sun X, Dong J, Huang J
Life sciences 2020 Sep 15;257:118040
Life sciences 2020 Sep 15;257:118040
Inflammasome/NF-κB translocation inhibition via PPARγ agonist mitigates inorganic mercury induced nephrotoxicity.
Li S, Shi M, Wan Y, Wang Y, Zhu M, Wang B, Zhan Y, Ran B, Wu C
Ecotoxicology and environmental safety 2020 Sep 15;201:110801
Ecotoxicology and environmental safety 2020 Sep 15;201:110801
FUT9-Driven Programming of Colon Cancer Cells towards a Stem Cell-Like State.
Blanas A, Zaal A, van der Haar Àvila I, Kempers M, Kruijssen L, de Kok M, Popovic MA, van der Horst JC, J van Vliet S
Cancers 2020 Sep 10;12(9)
Cancers 2020 Sep 10;12(9)
Adenovirus-mediated specific tumor tagging facilitates CAR-T therapy against antigen-mismatched solid tumors.
Tang X, Li Y, Ma J, Wang X, Zhao W, Hossain MA, Yang Y
Cancer letters 2020 Sep 1;487:1-9
Cancer letters 2020 Sep 1;487:1-9
The AKT/GSK3-Mediated Slug Expression Contributes to Oxaliplatin Resistance in Colorectal Cancer via Upregulation of ERCC1.
Wei W, Ma XD, Jiang GM, Shi B, Zhong W, Sun CL, Zhao L, Hou YJ, Wang H
Oncology research 2020 Sep 1;28(4):423-438
Oncology research 2020 Sep 1;28(4):423-438
Combination of luteolin and lycopene effectively protect against the "two-hit" in NAFLD through Sirt1/AMPK signal pathway.
Zhu Y, Liu R, Shen Z, Cai G
Life sciences 2020 Sep 1;256:117990
Life sciences 2020 Sep 1;256:117990
Four active monomers from Moutan Cortex exert inhibitory effects against oxidative stress by activating Nrf2/Keap1 signaling pathway.
Zhang B, Yu D, Luo N, Yang C, Zhu Y
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2020 Sep 1;24(5):373-384
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2020 Sep 1;24(5):373-384
Herpes Simplex Virus Type 2 Inhibits Type I IFN Signaling Mediated by the Novel E3 Ubiquitin Protein Ligase Activity of Viral Protein ICP22.
Zhang M, Fu M, Li M, Hu H, Gong S, Hu Q
Journal of immunology (Baltimore, Md. : 1950) 2020 Sep 1;205(5):1281-1292
Journal of immunology (Baltimore, Md. : 1950) 2020 Sep 1;205(5):1281-1292
Targeting SLC7A11 specifically suppresses the progression of colorectal cancer stem cells via inducing ferroptosis.
Xu X, Zhang X, Wei C, Zheng D, Lu X, Yang Y, Luo A, Zhang K, Duan X, Wang Y
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2020 Sep 1;152:105450
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2020 Sep 1;152:105450
Expression Level of Small Envelope Protein in Addition to Sequence Divergence inside Its Major Hydrophilic Region Contributes to More Efficient Surface Antigen Secretion by Hepatitis B Virus Subgenotype D2 than Subgenotype A2.
Wang Q, Fu S, Zhang J, Yuan Q, Li J, Xia N, Wen YM, Wang Y, Tong S
Viruses 2020 Sep 1;12(9)
Viruses 2020 Sep 1;12(9)
Down-regulation of NTSR3 inhibits cell growth and metastasis, as well as the PI3K-AKT and MAPK signaling pathways in colorectal cancer.
Liu A, Zuo Z, Liu L, Liu L
Biochemistry and cell biology = Biochimie et biologie cellulaire 2020 Oct;98(5):548-555
Biochemistry and cell biology = Biochimie et biologie cellulaire 2020 Oct;98(5):548-555
Cytotoxic effects of vitamins K1, K2, and K3 against human T lymphoblastoid leukemia cells through apoptosis induction and cell cycle arrest.
Xu W, Wu H, Chen S, Wang X, Tanaka S, Sugiyama K, Yamada H, Hirano T
Chemical biology & drug design 2020 Oct;96(4):1134-1147
Chemical biology & drug design 2020 Oct;96(4):1134-1147
Ubiquitin specific protease 5 negatively regulates the IFNs-mediated antiviral activity via targeting SMURF1.
Qian G, Zhu L, Huang C, Liu Y, Ren Y, Ding Y, Qian W, Xu Q, Zheng H, Lv H
International immunopharmacology 2020 Oct;87:106763
International immunopharmacology 2020 Oct;87:106763
Lycopene protects neuroblastoma cells against oxidative damage via depression of ER stress.
Ou S, Fang Y, Tang H, Wu T, Chen L, Jiang M, Zhou L, Xu J, Guo K
Journal of food science 2020 Oct;85(10):3552-3561
Journal of food science 2020 Oct;85(10):3552-3561
Upregulation of secreted phosphoprotein 1 affects malignant progression, prognosis, and resistance to cetuximab via the KRAS/MEK pathway in head and neck cancer.
Liu K, Hu H, Jiang H, Liu C, Zhang H, Gong S, Wei D, Yu Z
Molecular carcinogenesis 2020 Oct;59(10):1147-1158
Molecular carcinogenesis 2020 Oct;59(10):1147-1158
Resveratrol modulates the apoptosis and autophagic death of human lung adenocarcinoma A549 cells via a p53‑dependent pathway: Integrated bioinformatics analysis and experimental validation.
Fan Y, Li J, Yang Y, Zhao X, Liu Y, Jiang Y, Zhou L, Feng Y, Yu Y, Cheng Y
International journal of oncology 2020 Oct;57(4):925-938
International journal of oncology 2020 Oct;57(4):925-938
Schisandrin A restrains osteoclastogenesis by inhibiting reactive oxygen species and activating Nrf2 signalling.
Ni S, Qian Z, Yuan Y, Li D, Zhong Z, Ghorbani F, Zhang X, Zhang F, Zhang Z, Liu Z, Yu B
Cell proliferation 2020 Oct;53(10):e12882
Cell proliferation 2020 Oct;53(10):e12882
YY1-mediated PTEN dephosphorylation antagonizes IR-induced DNA repair contributing to tongue squamous cell carcinoma radiosensitization.
Zhao L, Li R, Qiu JZ, Yu JB, Cao Y, Yuan RT
Molecular and cellular probes 2020 Oct;53:101577
Molecular and cellular probes 2020 Oct;53:101577
Spatiotemporal expression of neurogenic locus notch homolog protein 1 in developing caudal spinal cord of fetuses with anorectal malformations from ETU-fed rats.
Yang Z, Jia H, Bai Y, Wang W
Journal of molecular histology 2020 Oct;51(5):519-530
Journal of molecular histology 2020 Oct;51(5):519-530
Silica nanoparticles induce spermatogenesis disorders via L3MBTL2-DNA damage-p53 apoptosis and RNF8-ubH2A/ubH2B pathway in mice.
Liu J, Li X, Zhou G, Sang Y, Zhang Y, Zhao Y, Ge W, Sun Z, Zhou X
Environmental pollution (Barking, Essex : 1987) 2020 Oct;265(Pt A):114974
Environmental pollution (Barking, Essex : 1987) 2020 Oct;265(Pt A):114974
Autophagy plays a protective role during Pseudomonas aeruginosa-induced apoptosis via ROS-MAPK pathway.
Han L, Ma Q, Yu J, Gong Z, Ma C, Xu Y, Deng G, Wu X
Innate immunity 2020 Oct;26(7):580-591
Innate immunity 2020 Oct;26(7):580-591
LKB1-MARK2 signalling mediates lipopolysaccharide-induced production of cytokines in mouse macrophages.
Deng J, Wen C, Ding X, Zhang X, Hou G, Liu A, Xu H, Cao X, Bai Y
Journal of cellular and molecular medicine 2020 Oct;24(19):11307-11317
Journal of cellular and molecular medicine 2020 Oct;24(19):11307-11317
Dihydrotanshinone I inhibits ovarian cancer cell proliferation and migration by transcriptional repression of PIK3CA gene.
Wang X, Xu X, Jiang G, Zhang C, Liu L, Kang J, Wang J, Owusu L, Zhou L, Zhang L, Li W
Journal of cellular and molecular medicine 2020 Oct;24(19):11177-11187
Journal of cellular and molecular medicine 2020 Oct;24(19):11177-11187
KIAA1429 regulates cell proliferation by targeting c-Jun messenger RNA directly in gastric cancer.
Miao R, Dai CC, Mei L, Xu J, Sun SW, Xing YL, Wu LS, Wang MH, Wei JF
Journal of cellular physiology 2020 Oct;235(10):7420-7432
Journal of cellular physiology 2020 Oct;235(10):7420-7432
Silencing long non‑coding RNA NEAT1 suppresses the tumorigenesis of infantile hemangioma by competitively binding miR‑33a‑5p to stimulate HIF1α/NF‑κB pathway.
Yu L, Shu H, Xing L, Lv MX, Li L, Xie YC, Zhang Z, Zhang L, Xie YY
Molecular medicine reports 2020 Oct;22(4):3358-3366
Molecular medicine reports 2020 Oct;22(4):3358-3366
Arsenic (III) and/or copper (II) induces oxidative stress in chicken brain and subsequent effects on mitochondrial homeostasis and autophagy.
Liu Y, Zhao H, Wang Y, Guo M, Mu M, Xing M
Journal of inorganic biochemistry 2020 Oct;211:111201
Journal of inorganic biochemistry 2020 Oct;211:111201
Dihydrotanshinone I inhibits human glioma cell proliferation via the activation of ferroptosis.
Tan S, Hou X, Mei L
Oncology letters 2020 Oct;20(4):122
Oncology letters 2020 Oct;20(4):122
Essential roles of S100A10 in Toll-like receptor signaling and immunity to infection.
Lou Y, Han M, Liu H, Niu Y, Liang Y, Guo J, Zhang W, Wang H
Cellular & molecular immunology 2020 Oct;17(10):1053-1062
Cellular & molecular immunology 2020 Oct;17(10):1053-1062
miR-103a-3p regulates mitophagy in Parkinson's disease through Parkin/Ambra1 signaling.
Zhou J, Zhao Y, Li Z, Zhu M, Wang Z, Li Y, Xu T, Feng D, Zhang S, Tang F, Yao J
Pharmacological research 2020 Oct;160:105197
Pharmacological research 2020 Oct;160:105197
p53 promotes ZDHHC1-mediated IFITM3 palmitoylation to inhibit Japanese encephalitis virus replication.
Wang X, Wu Z, Li Y, Yang Y, Xiao C, Liu X, Xiang X, Wei J, Shao D, Liu K, Deng X, Wu J, Qiu Y, Li B, Ma Z
PLoS pathogens 2020 Oct;16(10):e1009035
PLoS pathogens 2020 Oct;16(10):e1009035
A Histomorphological Study of the Divergent Corpus Spongiosum Surrounding the Urethral Plate in Hypospadias.
Bao X, Huang Y, Lyu Y, Xi Z, Xie H, Fu Q, Song L, Chen F
Urology 2020 Oct;144:188-193
Urology 2020 Oct;144:188-193
Exosomal miR-1255b-5p targets human telomerase reverse transcriptase in colorectal cancer cells to suppress epithelial-to-mesenchymal transition.
Zhang X, Bai J, Yin H, Long L, Zheng Z, Wang Q, Chen F, Yu X, Zhou Y
Molecular oncology 2020 Oct;14(10):2589-2608
Molecular oncology 2020 Oct;14(10):2589-2608
Polydatin alleviates parkinsonism in MPTP-model mice by enhancing glycolysis in dopaminergic neurons.
Zhang S, Wang S, Shi X, Feng X
Neurochemistry international 2020 Oct;139:104815
Neurochemistry international 2020 Oct;139:104815
Proteomic analyses reveal that Orf virus induces the activation and maturation of mouse bone marrow-derived dendritic cells.
Feng Q, Li L, Du G, Liu Y, Liu X, Wu J, Shang Y
Research in veterinary science 2020 Oct;132:563-573
Research in veterinary science 2020 Oct;132:563-573
Biomechanically reduced expression of Derlin-3 is linked to the apoptosis of chondrocytes in the mandibular condylar cartilage via the endoplasmic reticulum stress pathway.
Liu J, Yang H, Zhang H, Liu Q, Zhou P, He F, Zhang M, Yu S, Liu J, Wang M
Archives of oral biology 2020 Oct;118:104843
Archives of oral biology 2020 Oct;118:104843
T-type calcium channel blockade induces apoptosis in C2C12 myotubes and skeletal muscle via endoplasmic reticulum stress activation.
Chen M, Li S, Hao M, Chen J, Zhao Z, Hong S, Min J, Tang J, Hu M, Hong L
FEBS open bio 2020 Oct;10(10):2122-2136
FEBS open bio 2020 Oct;10(10):2122-2136
Impaired NLRP3 inflammasome activation/pyroptosis leads to robust inflammatory cell death via caspase-8/RIPK3 during coronavirus infection.
Zheng M, Williams EP, Malireddi RKS, Karki R, Banoth B, Burton A, Webby R, Channappanavar R, Jonsson CB, Kanneganti TD
The Journal of biological chemistry 2020 Oct 9;295(41):14040-14052
The Journal of biological chemistry 2020 Oct 9;295(41):14040-14052
Calreticulin promotes EMT in pancreatic cancer via mediating Ca2+ dependent acute and chronic endoplasmic reticulum stress.
Sheng W, Wang G, Tang J, Shi X, Cao R, Sun J, Lin YH, Jia C, Chen C, Zhou J, Dong M
Journal of experimental & clinical cancer research : CR 2020 Oct 7;39(1):209
Journal of experimental & clinical cancer research : CR 2020 Oct 7;39(1):209
Profiling pro-neural to mesenchymal transition identifies a lncRNA signature in glioma.
Liang Q, Guan G, Li X, Wei C, Wu J, Cheng P, Wu A, Cheng W
Journal of translational medicine 2020 Oct 7;18(1):378
Journal of translational medicine 2020 Oct 7;18(1):378
Revealing active ingredients, potential targets, and action mechanism of Ermiao fang for treating endometritis based on network pharmacology strategy.
Zhang C, Su T, Yu D, Wang F, Yue C, Wang HQ
Journal of ethnopharmacology 2020 Oct 5;260:113051
Journal of ethnopharmacology 2020 Oct 5;260:113051
c-Myc inactivation of p53 through the pan-cancer lncRNA MILIP drives cancer pathogenesis.
Feng YC, Liu XY, Teng L, Ji Q, Wu Y, Li JM, Gao W, Zhang YY, La T, Tabatabaee H, Yan XG, Jamaluddin MFB, Zhang D, Guo ST, Scott RJ, Liu T, Thorne RF, Zhang XD, Jin L
Nature communications 2020 Oct 5;11(1):4980
Nature communications 2020 Oct 5;11(1):4980
Defect of SLC38A3 promotes epithelial-mesenchymal transition and predicts poor prognosis in esophageal squamous cell carcinoma.
Liu R, Hong R, Wang Y, Gong Y, Yeerken D, Yang D, Li J, Fan J, Chen J, Zhang W, Zhan Q
Chinese journal of cancer research = Chung-kuo yen cheng yen chiu 2020 Oct 31;32(5):547-563
Chinese journal of cancer research = Chung-kuo yen cheng yen chiu 2020 Oct 31;32(5):547-563
Transcriptomic and Proteomic Analysis Reveals Mechanisms of Patulin-Induced Cell Toxicity in Human Embryonic Kidney Cells.
Han N, Luo R, Liu J, Guo T, Feng J, Peng X
Toxins 2020 Oct 29;12(11)
Toxins 2020 Oct 29;12(11)
Anticancer Effects of Honokiol via Mitochondrial Dysfunction Are Strongly Enhanced by the Mitochondria-Targeting Carrier Berberine.
Shi X, Zhang T, Lou H, Song H, Li C, Fan P
Journal of medicinal chemistry 2020 Oct 22;63(20):11786-11800
Journal of medicinal chemistry 2020 Oct 22;63(20):11786-11800
Rosmarinic Acid Alleviates Inflammation, Apoptosis, and Oxidative Stress through Regulating miR-155-5p in a Mice Model of Parkinson's Disease.
Lv R, Du L, Zhou F, Yuan X, Liu X, Zhang L
ACS chemical neuroscience 2020 Oct 21;11(20):3259-3266
ACS chemical neuroscience 2020 Oct 21;11(20):3259-3266
miR-497 regulates fatty acid synthesis via LATS2 in bovine mammary epithelial cells.
Chen Z, Chu S, Liang Y, Xu T, Sun Y, Li M, Zhang H, Wang X, Mao Y, Loor JJ, Wu Y, Yang Z
Food & function 2020 Oct 21;11(10):8625-8636
Food & function 2020 Oct 21;11(10):8625-8636
Amorphous silica nanoparticles accelerated atherosclerotic lesion progression in ApoE-/- mice through endoplasmic reticulum stress-mediated CD36 up-regulation in macrophage.
Ma R, Qi Y, Zhao X, Li X, Sun X, Niu P, Li Y, Guo C, Chen R, Sun Z
Particle and fibre toxicology 2020 Oct 2;17(1):50
Particle and fibre toxicology 2020 Oct 2;17(1):50
Sodium butyrate promotes milk fat synthesis in bovine mammary epithelial cells via GPR41 and its downstream signalling pathways.
Cheng J, Zhang Y, Ge Y, Li W, Cao Y, Qu Y, Liu S, Guo Y, Fu S, Liu J
Life sciences 2020 Oct 15;259:118375
Life sciences 2020 Oct 15;259:118375
Designing an eEF2K-Targeting PROTAC small molecule that induces apoptosis in MDA-MB-231 cells.
Liu Y, Zhen Y, Wang G, Yang G, Fu L, Liu B, Ouyang L
European journal of medicinal chemistry 2020 Oct 15;204:112505
European journal of medicinal chemistry 2020 Oct 15;204:112505
Sestrin2 promotes angiogenesis to alleviate brain injury by activating Nrf2 through regulating the interaction between p62 and Keap1 following photothrombotic stroke in rats.
Li Y, Wu J, Yu S, Zhu J, Zhou Y, Wang P, Li L, Zhao Y
Brain research 2020 Oct 15;1745:146948
Brain research 2020 Oct 15;1745:146948
Upregulation of Glutaredoxin 2 alleviates oxygen-glucose deprivation/reoxygenation-induced apoptosis and ROS production in neurons by enhancing Nrf2 signaling via modulation of GSK-3β.
Wen J, Li X, Zheng S, Xiao Y
Brain research 2020 Oct 15;1745:146946
Brain research 2020 Oct 15;1745:146946
A novel bile acid analog, A17, ameliorated non-alcoholic steatohepatitis in high-fat diet-fed hamsters.
Wang Y, Zhu Y, Niu J, Deng Q, Guo S, Jiang H, Peng Z, Xue Y, Peng H, Xuan L, Pan G
Toxicology and applied pharmacology 2020 Oct 1;404:115169
Toxicology and applied pharmacology 2020 Oct 1;404:115169
Polydatin executes anticancer effects against glioblastoma multiforme by inhibiting the EGFR-AKT/ERK1/2/STAT3-SOX2/Snail signaling pathway.
Chen Y, Niu J, Li L, Li Z, Jiang J, Zhu M, Dong T, Zhang J, Shi C, Xu P, Lu Y, Jiang Y, Liu P, Chen W
Life sciences 2020 Oct 1;258:118158
Life sciences 2020 Oct 1;258:118158
Notch1 contributes to TNF-α-induced proliferation and migration of airway smooth muscle cells through regulation of the Hes1/PTEN axis.
Li X, Zou F, Lu Y, Fan X, Wu Y, Feng X, Sun X, Liu Y
International immunopharmacology 2020 Nov;88:106911
International immunopharmacology 2020 Nov;88:106911
Knockdown of fatty acid binding protein 4 exacerbates Bacillus Calmette-Guerin infection-induced RAW264.7 cell apoptosis via the endoplasmic reticulum stress pathway.
Yu J, Ma C, Xu Y, Han L, Wu X, Wang Y, Deng G
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2020 Nov;85:104552
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2020 Nov;85:104552
Enhanced therapeutic efficacy of a novel colon-specific nanosystem loading emodin on DSS-induced experimental colitis.
Wang D, Sun M, Zhang Y, Chen Z, Zang S, Li G, Li G, Clark AR, Huang J, Si L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2020 Nov;78:153293
Phytomedicine : international journal of phytotherapy and phytopharmacology 2020 Nov;78:153293
CaMKII as a key regulator of contrast-induced nephropathy through mPTP opening in HK-2 cells.
Hu C, Zhou G, Liu K, Yin W, Zhou L, Wang J, Chen L, Zuo S, Xie Y, Zuo X
Cellular signalling 2020 Nov;75:109734
Cellular signalling 2020 Nov;75:109734
Histone demethylase Jmjd3 modulates osteoblast apoptosis induced by tumor necrosis factor-alpha through directly targeting RASSF5.
Sun HY, Yang D, Mi J, Yu YQ, Qiu LH
Connective tissue research 2020 Nov;61(6):517-525
Connective tissue research 2020 Nov;61(6):517-525
RNA binding motif protein 10 suppresses lung cancer progression by controlling alternative splicing of eukaryotic translation initiation factor 4H.
Zhang S, Bao Y, Shen X, Pan Y, Sun Y, Xiao M, Chen K, Wei H, Zuo J, Saffen D, Zong WX, Sun Y, Wang Z, Wang Y
EBioMedicine 2020 Nov;61:103067
EBioMedicine 2020 Nov;61:103067
Spatiotemporal heterogeneity of PPARγ expression in porcine uteroplacenta for regulating of placental angiogenesis through VEGF-mediated signalling.
Zhang J, Xue L, Nie A, Yang Q, Peng X, Chen Z, Yang L, Xie Y, Yuan A, Xu J
Reproduction in domestic animals = Zuchthygiene 2020 Nov;55(11):1479-1489
Reproduction in domestic animals = Zuchthygiene 2020 Nov;55(11):1479-1489
Identification of octopus peptide and its promotion of β-casein synthesis in a mouse mammary epithelial cell line.
Cai B, Wan P, Chen H, Chen X, Sun H, Pan J
Journal of food biochemistry 2020 Nov;44(11):e13467
Journal of food biochemistry 2020 Nov;44(11):e13467
Low-intensity pulsed ultrasound protects subchondral bone in rabbit temporomandibular joint osteoarthritis by suppressing TGF-β1/Smad3 pathway.
Yi X, Wu L, Liu J, Qin YX, Li B, Zhou Q
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2020 Nov;38(11):2505-2512
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2020 Nov;38(11):2505-2512
Involvement of NMDAR/PSD-95/nNOS-NO-cGMP pathway in embryonic exposure to BPA induced learning and memory dysfunction of rats.
Yu H, Ma L, Liu D, Wang Y, Pei X, Duan Z, Ma M, Zhang Y
Environmental pollution (Barking, Essex : 1987) 2020 Nov;266(Pt 1):115055
Environmental pollution (Barking, Essex : 1987) 2020 Nov;266(Pt 1):115055
Long noncoding RNA LINC00346 promotes glioma cell migration, invasion and proliferation by up-regulating ROCK1.
Chen X, Li D, Chen L, Hao B, Gao Y, Li L, Zhou C, He X, Cao Y
Journal of cellular and molecular medicine 2020 Nov;24(22):13010-13019
Journal of cellular and molecular medicine 2020 Nov;24(22):13010-13019
MicroRNA-127-5p impairs function of granulosa cells via HMGB2 gene in premature ovarian insufficiency.
Zhang X, Dang Y, Liu R, Zhao S, Ma J, Qin Y
Journal of cellular physiology 2020 Nov;235(11):8826-8838
Journal of cellular physiology 2020 Nov;235(11):8826-8838
Oxidative stress is important in the pathogenesis of stress-related mucosal disease.
Wang X, Zhao Q, Shi H, Qi F, Shi N, Bai D, Li X, Yuan H, Zuo X
Experimental and therapeutic medicine 2020 Nov;20(5):83
Experimental and therapeutic medicine 2020 Nov;20(5):83
Brilliant blue G attenuates neuro-inflammation via regulating MAPKs and NF-κB signaling pathways in lipopolysaccharide-induced BV2 microglia cells.
Wang W, Huang F, Jiang W, Wang W, Xiang J
Experimental and therapeutic medicine 2020 Nov;20(5):116
Experimental and therapeutic medicine 2020 Nov;20(5):116
Methylprednisolone potentiates tetrandrine pharmacodynamics against human T lymphoblastoid leukemia MOLT-4 cells via regulation of NF-κB activation and cell cycle transition.
Xu W, Chen S, Wang X, Wu H, Yamada H, Hirano T
Steroids 2020 Nov;163:108714
Steroids 2020 Nov;163:108714
Activation of angiotensin II type-2 receptor protects against cigarette smoke-induced COPD.
Mei D, Tan WSD, Liao W, Heng CKM, Wong WSF
Pharmacological research 2020 Nov;161:105223
Pharmacological research 2020 Nov;161:105223
Up-regulation of astrocyte excitatory amino acid transporter 2 alleviates central sensitization in a rat model of chronic migraine.
Zhou X, Liang J, Wang J, Fei Z, Qin G, Zhang D, Zhou J, Chen L
Journal of neurochemistry 2020 Nov;155(4):370-389
Journal of neurochemistry 2020 Nov;155(4):370-389
TRIM25 upregulation by Mycobacterium tuberculosis infection promotes intracellular survival of M.tb in RAW264.7 cells.
Liu H, Zhu T, Li Q, Xiong X, Wang J, Zhu X, Zhou X, Zhang L, Zhu Y, Peng Y, Chen Y, Hu C, Chen H, Guo A
Microbial pathogenesis 2020 Nov;148:104456
Microbial pathogenesis 2020 Nov;148:104456
Indirubin alleviates bleomycin-induced pulmonary fibrosis in mice by suppressing fibroblast to myofibroblast differentiation.
Wang Q, Yu J, Hu Y, Chen X, Zhang L, Pan T, Miao K, Mou Y, Xu Y, Xiong W, Wang Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Nov;131:110715
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Nov;131:110715
Nucleoredoxin interaction with flightless-I/actin complex is differentially altered in alcoholic liver disease.
Alarcón-Sánchez BR, Guerrero-Escalera D, Rosas-Madrigal S, Ivette Aparicio-Bautista D, Reyes-Gordillo K, Lakshman MR, Ortiz-Fernández A, Quezada H, Medina-Contreras Ó, Villa-Treviño S, Isael Pérez-Carreón J, Arellanes-Robledo J
Basic & clinical pharmacology & toxicology 2020 Nov;127(5):389-404
Basic & clinical pharmacology & toxicology 2020 Nov;127(5):389-404
Mycoplasma bovis-generated reactive oxygen species and induced apoptosis in bovine mammary epithelial cell cultures.
Liu Y, Zhou M, Xu S, Khan MA, Shi Y, Qu W, Gao J, Liu G, Kastelic JP, Han B
Journal of dairy science 2020 Nov;103(11):10429-10445
Journal of dairy science 2020 Nov;103(11):10429-10445
Sox13 promotes hepatocellular carcinoma metastasis by transcriptionally activating Twist1.
Feng M, Fang F, Fang T, Jiao H, You S, Wang X, Zhao W
Laboratory investigation; a journal of technical methods and pathology 2020 Nov;100(11):1400-1410
Laboratory investigation; a journal of technical methods and pathology 2020 Nov;100(11):1400-1410
TMEM176A acts as a tumor suppressor gene in pancreatic cancer by inhibiting ERK signaling.
Guo Y, Cao F, Hu S, Liu S, Sun H, Li A, Li F
Discovery medicine 2020 Nov-Dec;30(161):145-153
Discovery medicine 2020 Nov-Dec;30(161):145-153
Deficiency of microglial Hv1 channel is associated with activation of autophagic pathway and ROS production in LPC-induced demyelination mouse model.
Chen M, Yang LL, Hu ZW, Qin C, Zhou LQ, Duan YL, Bosco DB, Wu LJ, Zhan KB, Xu SB, Tian DS
Journal of neuroinflammation 2020 Nov 6;17(1):333
Journal of neuroinflammation 2020 Nov 6;17(1):333
Effects of Osthole on Progesterone Secretion in Chicken Preovulatory Follicles Granulosa Cells.
Sun N, Zhang Y, Hou Y, Yi Y, Guo J, Zheng X, Sun P, Sun Y, Khan A, Li H
Animals : an open access journal from MDPI 2020 Nov 4;10(11)
Animals : an open access journal from MDPI 2020 Nov 4;10(11)
Amino acid transporter LAT1 in tumor-associated vascular endothelium promotes angiogenesis by regulating cell proliferation and VEGF-A-dependent mTORC1 activation.
Quan L, Ohgaki R, Hara S, Okuda S, Wei L, Okanishi H, Nagamori S, Endou H, Kanai Y
Journal of experimental & clinical cancer research : CR 2020 Nov 30;39(1):266
Journal of experimental & clinical cancer research : CR 2020 Nov 30;39(1):266
Anthocyanins decrease the internalization of TiO2 nanoparticles into 3D Caco-2 spheroids.
Wang J, Zhang J, Li S, Huang C, Xie Y, Cao Y
Food chemistry 2020 Nov 30;331:127360
Food chemistry 2020 Nov 30;331:127360
Hypoxia induces sorafenib resistance mediated by autophagy via activating FOXO3a in hepatocellular carcinoma.
Liang C, Dong Z, Cai X, Shen J, Xu Y, Zhang M, Li H, Yu W, Chen W
Cell death & disease 2020 Nov 29;11(11):1017
Cell death & disease 2020 Nov 29;11(11):1017
Effective RNA Knockdown Using CRISPR-Cas13a and Molecular Targeting of the EML4-ALK Transcript in H3122 Lung Cancer Cells.
Saifullah, Sakari M, Suzuki T, Yano S, Tsukahara T
International journal of molecular sciences 2020 Nov 24;21(23)
International journal of molecular sciences 2020 Nov 24;21(23)
MiR-103a-3p promotes tumour glycolysis in colorectal cancer via hippo/YAP1/HIF1A axis.
Sun Z, Zhang Q, Yuan W, Li X, Chen C, Guo Y, Shao B, Dang Q, Zhou Q, Wang Q, Wang G, Liu J, Kan Q
Journal of experimental & clinical cancer research : CR 2020 Nov 20;39(1):250
Journal of experimental & clinical cancer research : CR 2020 Nov 20;39(1):250
Velvet antler polypeptide prevents the disruption of hepatic tight junctions via inhibiting oxidative stress in cholestatic mice and liver cell lines.
Li L, Yang F, Jia R, Yan P, Ma L
Food & function 2020 Nov 18;11(11):9752-9763
Food & function 2020 Nov 18;11(11):9752-9763
Identification of Milk Fat Metabolism-Related Pathways of the Bovine Mammary Gland during Mid and Late Lactation and Functional Verification of the ACSL4 Gene.
Fan Y, Han Z, Lu X, Zhang H, Arbab AAI, Loor JJ, Yang Y, Yang Z
Genes 2020 Nov 16;11(11)
Genes 2020 Nov 16;11(11)
Eurocristatine, a plant alkaloid from Eurotium cristatum, alleviates insulin resistance in db/db diabetic mice via activation of PI3K/AKT signaling pathway.
Zhang H, Hui J, Yang J, Deng J, Fan D
European journal of pharmacology 2020 Nov 15;887:173557
European journal of pharmacology 2020 Nov 15;887:173557
Baicalein ameliorates ionizing radiation-induced injuries by rebalancing gut microbiota and inhibiting apoptosis.
Wang M, Dong Y, Wu J, Li H, Zhang Y, Fan S, Li D
Life sciences 2020 Nov 15;261:118463
Life sciences 2020 Nov 15;261:118463
A novel polysaccharide from Acorus tatarinowii protects against LPS-induced neuroinflammation and neurotoxicity by inhibiting TLR4-mediated MyD88/NF-κB and PI3K/Akt signaling pathways.
Zhong J, Qiu X, Yu Q, Chen H, Yan C
International journal of biological macromolecules 2020 Nov 15;163:464-475
International journal of biological macromolecules 2020 Nov 15;163:464-475
Binding properties of marine bromophenols with human protein tyrosine phosphatase 1B: Molecular docking, surface plasmon resonance and cellular insulin resistance study.
Luo J, Zhang R, Wang X, Hou Z, Guo S, Jiang B
International journal of biological macromolecules 2020 Nov 15;163:200-208
International journal of biological macromolecules 2020 Nov 15;163:200-208
Targeting HMGB3/hTERT axis for radioresistance in cervical cancer.
Li Z, Zhang Y, Sui S, Hua Y, Zhao A, Tian X, Wang R, Guo W, Yu W, Zou K, Deng W, He L, Zou L
Journal of experimental & clinical cancer research : CR 2020 Nov 13;39(1):243
Journal of experimental & clinical cancer research : CR 2020 Nov 13;39(1):243
Synergism of TNF-α and IFN-γ triggers inflammatory cell death, tissue damage, and mortality in SARS-CoV-2 infection and cytokine shock syndromes.
Karki R, Sharma BR, Tuladhar S, Williams EP, Zalduondo L, Samir P, Zheng M, Sundaram B, Banoth B, Malireddi RKS, Schreiner P, Neale G, Vogel P, Webby R, Jonsson CB, Kanneganti TD
bioRxiv : the preprint server for biology 2020 Nov 13;
bioRxiv : the preprint server for biology 2020 Nov 13;
Duck enteritis virus pUL47, as a late structural protein localized in the nucleus, mainly depends on residues 40 to 50 and 768 to 777 and inhibits IFN-β signalling by interacting with STAT1.
He T, Wang M, Cheng A, Yang Q, Jia R, Wu Y, Huang J, Chen S, Zhao XX, Liu M, Zhu D, Zhang S, Ou X, Mao S, Gao Q, Sun D, Wen X, Tian B, Liu Y, Yu Y, Zhang L, Pan L, Chen X
Veterinary research 2020 Nov 11;51(1):135
Veterinary research 2020 Nov 11;51(1):135
Immunoproteasome is up-regulated in rotenone-induced Parkinson's disease rat model.
Sun C, Jia G, Wang X, Wang Y, Liu Y
Neuroscience letters 2020 Nov 1;738:135360
Neuroscience letters 2020 Nov 1;738:135360
Berberine inhibits proliferation and induces G0/G1 phase arrest in colorectal cancer cells by downregulating IGF2BP3.
Zhang Y, Liu X, Yu M, Xu M, Xiao Y, Ma W, Huang L, Li X, Ye X
Life sciences 2020 Nov 1;260:118413
Life sciences 2020 Nov 1;260:118413
iTRAQ-based quantitative proteomic analysis of the therapeutic effects of 2% hydrogen gas inhalation on brain injury in septic mice.
Xie K, Lian N, Kan Y, Yang M, Pan J, Yu Y, Yu Y
Brain research 2020 Nov 1;1746:147003
Brain research 2020 Nov 1;1746:147003
Combination of N, N'-dicyclohexyl-N-arachidonic acylurea and tacrolimus prolongs cardiac allograft survival in mice.
An K, Qin Q, Yu S, Xue M, Wang Z, Lin Q, Ma Y, Yan G, Mo S, Chen Y, Zhang L, Zhong J, Qi Z, Xia J
Immunology and cell biology 2020 May;98(5):382-396
Immunology and cell biology 2020 May;98(5):382-396
Long non-coding RNA OIP5-AS1 promotes pancreatic cancer cell growth through sponging miR-342-3p via AKT/ERK signaling pathway.
Meng X, Ma J, Wang B, Wu X, Liu Z
Journal of physiology and biochemistry 2020 May;76(2):301-315
Journal of physiology and biochemistry 2020 May;76(2):301-315
Role of fucosyltransferase IV in the migration and invasion of human melanoma cells.
Shan X, Dong W, Zhang L, Cai X, Zhao Y, Chen Q, Yan Q, Liu J
IUBMB life 2020 May;72(5):942-956
IUBMB life 2020 May;72(5):942-956
OGDHL silencing promotes hepatocellular carcinoma by reprogramming glutamine metabolism.
Dai W, Xu L, Yu X, Zhang G, Guo H, Liu H, Song G, Weng S, Dong L, Zhu J, Liu T, Guo C, Shen X
Journal of hepatology 2020 May;72(5):909-923
Journal of hepatology 2020 May;72(5):909-923
miR-142-5P regulates triglyceride by targeting CTNNB1 in goat mammary epithelial cells.
Sui M, Wang Z, Xi D, Wang H
Reproduction in domestic animals = Zuchthygiene 2020 May;55(5):613-623
Reproduction in domestic animals = Zuchthygiene 2020 May;55(5):613-623
Transcriptome sequencing analysis of mono‑ADP‑ribosylation in colorectal cancer cells.
Zhang NN, Lin T, Xiao M, Li QS, Li X, Yang L, Wang CL, Wang YL
Oncology reports 2020 May;43(5):1413-1428
Oncology reports 2020 May;43(5):1413-1428
Annexin-1 Mimetic Peptide Ac2-26 Suppresses Inflammatory Mediators in LPS-Induced Astrocytes and Ameliorates Pain Hypersensitivity in a Rat Model of Inflammatory Pain.
Luo Z, Wang H, Fang S, Li L, Li X, Shi J, Zhu M, Tan Z, Lu Z
Cellular and molecular neurobiology 2020 May;40(4):569-585
Cellular and molecular neurobiology 2020 May;40(4):569-585
Mitochondrial dysfunction is involved in aristolochic acid I-induced apoptosis in renal proximal tubular epithelial cells.
Liu X, Wu J, Wang J, Feng X, Wu H, Huang R, Fan J, Yu X, Yang X
Human & experimental toxicology 2020 May;39(5):673-682
Human & experimental toxicology 2020 May;39(5):673-682
Exogenous spermine attenuates rat diabetic cardiomyopathy via suppressing ROS-p53 mediated downregulation of calcium-sensitive receptor.
Wang Y, Chen J, Li S, Zhang X, Guo Z, Hu J, Shao X, Song N, Zhao Y, Li H, Yang G, Xu C, Wei C
Redox biology 2020 May;32:101514
Redox biology 2020 May;32:101514
Programmable prodrug micelle with size-shrinkage and charge-reversal for chemotherapy-improved IDO immunotherapy.
Dai L, Li X, Yao M, Niu P, Yuan X, Li K, Chen M, Fu Z, Duan X, Liu H, Cai K, Yang H
Biomaterials 2020 May;241:119901
Biomaterials 2020 May;241:119901
PM2.5 in poultry houses synergizes with Pseudomonas aeruginosa to aggravate lung inflammation in mice through the NF-κB pathway.
Li M, Wei X, Li Y, Feng T, Jiang L, Zhu H, Yu X, Tang J, Chen G, Zhang J, Zhang X
Journal of veterinary science 2020 May;21(3):e46
Journal of veterinary science 2020 May;21(3):e46
Shear stress stimulates integrin β1 trafficking and increases directional migration of cancer cells via promoting deacetylation of microtubules.
Tang K, Li S, Li P, Xia Q, Yang R, Li T, Li L, Jiang Y, Qin X, Yang H, Wu C, You F, Tan Y, Liu Y
Biochimica et biophysica acta. Molecular cell research 2020 May;1867(5):118676
Biochimica et biophysica acta. Molecular cell research 2020 May;1867(5):118676
TOPORS, a tumor suppressor protein, contributes to the maintenance of higher-order chromatin architecture.
Ji L, Huo X, Zhang Y, Yan Z, Wang Q, Wen B
Biochimica et biophysica acta. Gene regulatory mechanisms 2020 May;1863(5):194518
Biochimica et biophysica acta. Gene regulatory mechanisms 2020 May;1863(5):194518
Protective effect of cilastatin against diclofenac-induced nephrotoxicity through interaction with diclofenac acyl glucuronide via organic anion transporters.
Huo X, Meng Q, Wang C, Wu J, Wang C, Zhu Y, Ma X, Sun H, Liu K
British journal of pharmacology 2020 May;177(9):1933-1948
British journal of pharmacology 2020 May;177(9):1933-1948
Palmatine induces G2/M phase arrest and mitochondrial-associated pathway apoptosis in colon cancer cells by targeting AURKA.
Liu X, Zhang Y, Wu S, Xu M, Shen Y, Yu M, Fan J, Wei S, Xu C, Huang L, Zhao H, Li X, Ye X
Biochemical pharmacology 2020 May;175:113933
Biochemical pharmacology 2020 May;175:113933
Protective effect of ginsenoside Rg5 against kidney injury via inhibition of NLRP3 inflammasome activation and the MAPK signaling pathway in high-fat diet/streptozotocin-induced diabetic mice.
Zhu Y, Zhu C, Yang H, Deng J, Fan D
Pharmacological research 2020 May;155:104746
Pharmacological research 2020 May;155:104746
Elevated SRC3 expression predicts pemetrexed resistance in lung adenocarcinoma.
Chen Y, Sun Y, Zhao W, Ma Y, Yan Z, Nie X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109958
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109958
LncRNA MFI2-AS1 promotes HCC progression and metastasis by acting as a competing endogenous RNA of miR-134 to upregulate FOXM1 expression.
Wei Y, Wang Z, Zong Y, Deng D, Chen P, Lu J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109890
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109890
Protein kinase CK2 participates in estrogen-mediated endothelial progenitor cell homing to endometriotic lesions through stromal cells in a stromal cell-derived factor-1- CXCR4-dependent manner.
Zhao R, Feng D, Zhuang G, Liu Y, Chi S, Zhang J, Zhou X, Zhang W, Wang H
Fertility and sterility 2020 May;113(5):1067-1079.e5
Fertility and sterility 2020 May;113(5):1067-1079.e5
BMP8A promotes survival and drug resistance via Nrf2/TRIM24 signaling pathway in clear cell renal cell carcinoma.
Yu YP, Cai LC, Wang XY, Cheng SY, Zhang DM, Jian WG, Wang TD, Yang JK, Yang KB, Zhang C
Cancer science 2020 May;111(5):1555-1566
Cancer science 2020 May;111(5):1555-1566
Mitochondria-related miR-574 reduces sperm ATP by targeting ND5 in aging males.
Ma J, Chen Q, Wang S, Ma R, Jing J, Yang Y, Feng Y, Zou Z, Zhang Y, Ge X, Xue T, Liang K, Cao S, Wang D, Chen L, Yao B
Aging 2020 May 7;12(9):8321-8338
Aging 2020 May 7;12(9):8321-8338
Rare Neurologic Disease-Associated Mutations of AIMP1 are Related with Inhibitory Neuronal Differentiation Which is Reversed by Ibuprofen.
Takeuchi Y, Tanaka M, Okura N, Fukui Y, Noguchi K, Hayashi Y, Torii T, Ooizumi H, Ohbuchi K, Mizoguchi K, Miyamoto Y, Yamauchi J
Medicines (Basel, Switzerland) 2020 May 6;7(5)
Medicines (Basel, Switzerland) 2020 May 6;7(5)
Artesunate attenuates 2, 4-dinitrochlorobenzene-induced atopic dermatitis by down-regulating Th17 cell responses in BALB/c mice.
Bai XY, Liu P, Chai YW, Wang Y, Ren SH, Li YY, Zhou H
European journal of pharmacology 2020 May 5;874:173020
European journal of pharmacology 2020 May 5;874:173020
Effect of miR-195-5p on cardiomyocyte apoptosis in rats with heart failure by regulating TGF-β1/Smad3 signaling pathway.
Xie C, Qi H, Huan L, Yang Y
Bioscience reports 2020 May 29;40(5)
Bioscience reports 2020 May 29;40(5)
TET2-mediated Cdkn2A DNA hydroxymethylation in midbrain dopaminergic neuron injury of Parkinson's disease.
Wu TT, Liu T, Li X, Chen YJ, Chen TJ, Zhu XY, Chen JL, Li Q, Liu Y, Feng Y, Wu YC
Human molecular genetics 2020 May 28;29(8):1239-1252
Human molecular genetics 2020 May 28;29(8):1239-1252
The Lumiptosome, an engineered luminescent form of the apoptosome can report cell death by using the same Apaf-1 dependent pathway.
Hosseini ES, Nikkhah M, Hamidieh AA, Fearnhead HO, Concordet JP, Hosseinkhani S
Journal of cell science 2020 May 27;133(10)
Journal of cell science 2020 May 27;133(10)
P-21-activated kinase 1 contributes to tumor angiogenesis upon photodynamic therapy via the HIF-1α/VEGF pathway.
Jiang S, Gao Y, Yu QH, Li M, Cheng X, Hu SB, Song ZF, Zheng QC
Biochemical and biophysical research communications 2020 May 21;526(1):98-104
Biochemical and biophysical research communications 2020 May 21;526(1):98-104
Neddylation-mediated Nedd4-2 activation regulates ubiquitination modification of renal NBCe1.
Tu J, Zhang B, Fang G, Chang W, Zhao Y
Experimental cell research 2020 May 15;390(2):111958
Experimental cell research 2020 May 15;390(2):111958
Concentration and Duration of Indoxyl Sulfate Exposure Affects Osteoclastogenesis by Regulating NFATc1 via Aryl Hydrocarbon Receptor.
Liu WC, Shyu JF, Lim PS, Fang TC, Lu CL, Zheng CM, Hou YC, Wu CC, Lin YF, Lu KC
International journal of molecular sciences 2020 May 15;21(10)
International journal of molecular sciences 2020 May 15;21(10)
Androgen aggravates liver fibrosis by activation of NLRP3 inflammasome in CCl4-induced liver injury mouse model.
Ma X, Zhou Y, Qiao B, Jiang S, Shen Q, Han Y, Liu A, Chen X, Wei L, Zhou L, Zhao J
American journal of physiology. Endocrinology and metabolism 2020 May 1;318(5):E817-E829
American journal of physiology. Endocrinology and metabolism 2020 May 1;318(5):E817-E829
In vitro and in vivo anti-Listeria effect of Succinoglycan Riclin through regulating MAPK/IL-6 axis and metabolic profiling.
Wu Z, Cheng Y, Yang Y, Gao Y, Sun X, Wang L, Sun Q, Zhang J, Xu X
International journal of biological macromolecules 2020 May 1;150:802-813
International journal of biological macromolecules 2020 May 1;150:802-813
Blueberry Prevents the Bladder Dysfunction in Bladder Outlet Obstruction Rats by Attenuating Oxidative Stress and Suppressing Bladder Remodeling.
Miyazaki N, Katsura R, Hamada K, Suzutani T
Nutrients 2020 May 1;12(5)
Nutrients 2020 May 1;12(5)
Suppression of experimental atrial fibrillation in a canine model of rapid atrial pacing by the phosphodiesterase 3 inhibitor cilostazol.
Zhao Z, Li R, Wang X, Li J, Xu X, Liu T, Liu E, Li G
Journal of electrocardiology 2020 May - Jun;60:151-158
Journal of electrocardiology 2020 May - Jun;60:151-158
Ketamine attenuates high-glucose-mediated endothelial inflammation in human umbilical vein endothelial cells.
Wang T, Zhu H, Hou Y, Duan W, Meng F, Liu Y
Canadian journal of physiology and pharmacology 2020 Mar;98(3):156-161
Canadian journal of physiology and pharmacology 2020 Mar;98(3):156-161
Interleukin-4 Restores Insulin Sensitivity in Insulin-Resistant Osteoblasts by Increasing the Expression of Insulin Receptor Substrate 1.
Chao R, Li D, Yue Z, Huang C, Kou Y, Zhou Q, Gao Y, Hasegawa T, Guo J, Li M
Biochemistry. Biokhimiia 2020 Mar;85(3):334-343
Biochemistry. Biokhimiia 2020 Mar;85(3):334-343
NLRP6 expressed in astrocytes aggravates neurons injury after OGD/R through activating the inflammasome and inducing pyroptosis.
Zhang J, Jiang N, Zhang L, Meng C, Zhao J, Wu J
International immunopharmacology 2020 Mar;80:106183
International immunopharmacology 2020 Mar;80:106183
Dihydroartemisinin inhibits the proliferation of IgAN mesangial cells through the mTOR signaling pathway.
Xia M, Liu D, Tang X, Liu Y, Liu H, Liu Y, Chen G, Liu H
International immunopharmacology 2020 Mar;80:106125
International immunopharmacology 2020 Mar;80:106125
JTE-013 supplementation improves erectile dysfunction in rats with streptozotocin-induced type Ⅰ diabetes through the inhibition of the rho-kinase pathway, fibrosis, and apoptosis.
Liu K, Cui K, Feng H, Li R, Lin H, Chen Y, Zhang Y, Chen Z, Yuan H, Li M, Wang T, Lan R, Liu J, Rao K, Wen B
Andrology 2020 Mar;8(2):497-508
Andrology 2020 Mar;8(2):497-508
Danshen formula granule and salvianic acid A alleviate ethanol-induced neurotoxicity.
Li Y, Chen H, Yang Y, Niu M, Wang J, Wu Y, Niu L, Liu H, Bao D
Journal of natural medicines 2020 Mar;74(2):399-408
Journal of natural medicines 2020 Mar;74(2):399-408
Resveratrol protects the integrity of alveolar epithelial barrier via SIRT1/PTEN/p-Akt pathway in methamphetamine-induced chronic lung injury.
Wang X, Liu M, Zhu MJ, Shi L, Liu L, Zhao YL, Cheng L, Gu YJ, Zhou MY, Chen L, Kumar A, Wang Y
Cell proliferation 2020 Mar;53(3):e12773
Cell proliferation 2020 Mar;53(3):e12773
Integrin β3 Modulates TLR4-Mediated Inflammation by Regulation of CD14 Expression in Macrophages in Septic Condition.
Chen Z, Wang S, Chen Y, Shao Z, Yu Z, Mei S, Li Q
Shock (Augusta, Ga.) 2020 Mar;53(3):335-343
Shock (Augusta, Ga.) 2020 Mar;53(3):335-343
Inhibitory mechanism of muscone in liver cancer involves the induction of apoptosis and autophagy.
Qi W, Li Z, Yang C, Jiangshan Dai J, Zhang Q, Wang D, Wu C, Xia L, Xu S
Oncology reports 2020 Mar;43(3):839-850
Oncology reports 2020 Mar;43(3):839-850
Samarium enriches antitumor activity of ZnO nanoparticles via downregulation of CXCR4 receptor and cytochrome P450.
Nabeel AI
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2020 Mar;42(3):1010428320909999
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2020 Mar;42(3):1010428320909999
Cyclovirobuxine D Exerts Anticancer Effects by Suppressing the EGFR-FAK-AKT/ERK1/2-Slug Signaling Pathway in Human Hepatocellular Carcinoma.
Zhang J, Chen Y, Lin J, Jia R, An T, Dong T, Zhang Y, Yang X
DNA and cell biology 2020 Mar;39(3):355-367
DNA and cell biology 2020 Mar;39(3):355-367
Lysophosphatidic acid receptor 4 regulates osteogenic and adipogenic differentiation of progenitor cells via inactivation of RhoA/ROCK1/β-catenin signaling.
Xie Y, Wang X, Wu X, Tian L, Zhou J, Li X, Wang B
Stem cells (Dayton, Ohio) 2020 Mar;38(3):451-463
Stem cells (Dayton, Ohio) 2020 Mar;38(3):451-463
HUWE1 promotes EGFR ubiquitination and degradation to protect against renal tubulointerstitial fibrosis.
Zhu Q, Dong H, Bukhari AA, Zhao A, Li M, Sun Y, Zhang X, Cao C, Su D, Liang X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):4591-4601
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):4591-4601
Molecular hydrogen regulates PTEN-AKT-mTOR signaling via ROS to alleviate peritoneal dialysis-related peritoneal fibrosis.
Lu H, Chen W, Liu W, Si Y, Zhao T, Lai X, Kang Z, Sun X, Guo Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):4134-4146
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):4134-4146
Recombinant Human Milk Fat Globule-Epidermal Growth Factor 8 Attenuates Microthrombosis after Subarachnoid Hemorrhage in Rats.
Wang J, Zuo Y, Zhuang K, Luo K, Yan X, Li J, Zhang JH, Liu F
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2020 Mar;29(3):104536
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2020 Mar;29(3):104536
Blockade of HSP70 by VER-155008 synergistically enhances bortezomib-induced cytotoxicity in multiple myeloma.
Huang L, Wang Y, Bai J, Yang Y, Wang F, Feng Y, Zhang R, Li F, Zhang P, Lv N, Lei L, Hu J, He A
Cell stress & chaperones 2020 Mar;25(2):357-367
Cell stress & chaperones 2020 Mar;25(2):357-367
The marine-derived furanone reduces intracellular lipid accumulation in vitro by targeting LXRα and PPARα.
Li T, Hu SM, Pang XY, Wang JF, Yin JY, Li FH, Wang J, Yang XQ, Xia B, Liu YH, Song WG, Guo SD
Journal of cellular and molecular medicine 2020 Mar;24(6):3384-3398
Journal of cellular and molecular medicine 2020 Mar;24(6):3384-3398
Mechanism of the hypoxia inducible factor 1/hypoxic response element pathway in rat myocardial ischemia/diazoxide post‑conditioning.
Li J, Zhou W, Chen W, Wang H, Zhang Y, Yu T
Molecular medicine reports 2020 Mar;21(3):1527-1536
Molecular medicine reports 2020 Mar;21(3):1527-1536
Ginsenosides reduce body weight and ameliorate hepatic steatosis in high fat diet‑induced obese mice via endoplasmic reticulum stress and p‑STAT3/STAT3 signaling.
Yao Y
Molecular medicine reports 2020 Mar;21(3):1059-1070
Molecular medicine reports 2020 Mar;21(3):1059-1070
Cystatin C promotes cognitive dysfunction in rats with cerebral microbleeds by inhibiting the ERK/synapsin Ia/Ib pathway.
Yu G, Sun X, Li L, Huang L, Liu H, Wang S, Ren Z, Zhang Y
Experimental and therapeutic medicine 2020 Mar;19(3):2282-2290
Experimental and therapeutic medicine 2020 Mar;19(3):2282-2290
WHIMP links the actin nucleation machinery to Src-family kinase signaling during protrusion and motility.
Kabrawala S, Zimmer MD, Campellone KG
PLoS genetics 2020 Mar;16(3):e1008694
PLoS genetics 2020 Mar;16(3):e1008694
LongShengZhi capsule inhibits doxorubicin-induced heart failure by anti-oxidative stress.
Xu S, Wang Y, Yu M, Wang D, Liang Y, Chen Y, Liao C, Xie Z, Zhao B, Han J, Duan Y, Yang X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Mar;123:109803
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Mar;123:109803
The mechanism of PDA/PEI/5-Fu coated esophageal stent material on inhibiting cancer associated pathological cells.
Zhang K, Bai Y, Xu R, Li J, Guan F
Journal of biomedical materials research. Part A 2020 Mar;108(3):814-821
Journal of biomedical materials research. Part A 2020 Mar;108(3):814-821
DJ-1 exerts anti-inflammatory effects and regulates NLRX1-TRAF6 via SHP-1 in stroke.
Peng L, Zhou Y, Jiang N, Wang T, Zhu J, Chen Y, Li L, Zhang J, Yu S, Zhao Y
Journal of neuroinflammation 2020 Mar 9;17(1):81
Journal of neuroinflammation 2020 Mar 9;17(1):81
Transcription co-activator P300 activates Elk1-aPKC-ι signaling mediated epithelial-to-mesenchymal transition and malignancy in hepatocellular carcinoma.
Ma C, Huang S, Xu L, Tian L, Yang Y, Wang J
Oncogenesis 2020 Mar 6;9(3):32
Oncogenesis 2020 Mar 6;9(3):32
Quantitative Mitochondrial Proteomics Reveals ANXA7 as a Crucial Factor in Mitophagy.
Meng K, Lu S, Yan X, Sun Y, Gao J, Wang Y, Yin X, Sun Z, He QY
Journal of proteome research 2020 Mar 6;19(3):1275-1284
Journal of proteome research 2020 Mar 6;19(3):1275-1284
miR-17 regulates the proliferation and differentiation of retinal progenitor cells by targeting CHMP1A.
Sun N, Zhang D, Ni N, Tang Z, Gao H, Ju Y, Dai X, Wang J, Gu P, Ji J
Biochemical and biophysical research communications 2020 Mar 5;523(2):493-499
Biochemical and biophysical research communications 2020 Mar 5;523(2):493-499
SIRT3 inhibits cardiac hypertrophy by regulating PARP-1 activity.
Feng X, Wang Y, Chen W, Xu S, Li L, Geng Y, Shen A, Gao H, Zhang L, Liu S
Aging 2020 Mar 4;12(5):4178-4192
Aging 2020 Mar 4;12(5):4178-4192
BCAP31, a cancer/testis antigen-like protein, can act as a probe for non-small-cell lung cancer metastasis.
Wang J, Jiang D, Li Z, Yang S, Zhou J, Zhang G, Zhang Z, Sun Y, Zhang Z, Li X, Tao L, Shi J, Lu Y, Zheng L, Song C, Yang K
Scientific reports 2020 Mar 4;10(1):4025
Scientific reports 2020 Mar 4;10(1):4025
(20S)G-Rh2 Inhibits NF-κB Regulated Epithelial-Mesenchymal Transition by Targeting Annexin A2.
Wang YS, Li H, Li Y, Zhang S, Jin YH
Biomolecules 2020 Mar 31;10(4)
Biomolecules 2020 Mar 31;10(4)
5-HT1AR alleviates Aβ-induced cognitive decline and neuroinflammation through crosstalk with NF-κB pathway in mice.
Wang M, Zong HF, Chang KW, Han H, Yasir Rizvi M, Iffat Neha S, Li ZY, Yang WN, Qian YH
International immunopharmacology 2020 Mar 3;82:106354
International immunopharmacology 2020 Mar 3;82:106354
The Agpat4/LPA axis in colorectal cancer cells regulates antitumor responses via p38/p65 signaling in macrophages.
Zhang D, Shi R, Xiang W, Kang X, Tang B, Li C, Gao L, Zhang X, Zhang L, Dai R, Miao H
Signal transduction and targeted therapy 2020 Mar 27;5(1):24
Signal transduction and targeted therapy 2020 Mar 27;5(1):24
LINC00978 promotes hepatocellular carcinoma carcinogenesis partly via activating the MAPK/ERK pathway.
Zhang Q, Cheng S, Cao L, Yang J, Wang Y, Chen Y
Bioscience reports 2020 Mar 27;40(3)
Bioscience reports 2020 Mar 27;40(3)
Posttranslational lysine 2-hydroxyisobutyrylation of human sperm tail proteins affects motility.
Cheng YM, Peng Z, Chen HY, Pan TT, Hu XN, Wang F, Luo T
Human reproduction (Oxford, England) 2020 Mar 27;35(3):494-503
Human reproduction (Oxford, England) 2020 Mar 27;35(3):494-503
Design, Synthesis, and Biological Evaluation of Imidazo[1,2-a]pyridine Derivatives as Novel PI3K/mTOR Dual Inhibitors.
Yu Y, Han Y, Zhang F, Gao Z, Zhu T, Dong S, Ma M
Journal of medicinal chemistry 2020 Mar 26;63(6):3028-3046
Journal of medicinal chemistry 2020 Mar 26;63(6):3028-3046
Dendrobium officinale polysaccharides protected against ethanol-induced acute liver injury in vivo and in vitro via the TLR4/NF-κB signaling pathway.
Yang K, Zhan L, Lu T, Zhou C, Chen X, Dong Y, Lv G, Chen S
Cytokine 2020 Mar 26;130:155058
Cytokine 2020 Mar 26;130:155058
Optimization of Experimental Variables Influencing Apoptosome Biosensor in HEK293T Cells.
Oladzad A, Nikkhah M, Hosseinkhani S
Sensors (Basel, Switzerland) 2020 Mar 23;20(6)
Sensors (Basel, Switzerland) 2020 Mar 23;20(6)
Protective effects of panax notoginseng saponin on dextran sulfate sodium-induced colitis in rats through phosphoinositide-3-kinase protein kinase B signaling pathway inhibition.
Lu QG, Zeng L, Li XH, Liu Y, Du XF, Bai GM, Yan X
World journal of gastroenterology 2020 Mar 21;26(11):1156-1171
World journal of gastroenterology 2020 Mar 21;26(11):1156-1171
Extrahepatic deficiency of transferrin receptor 2 is associated with increased erythropoiesis independent of iron overload.
Wortham AM, Goldman DC, Chen J, Fleming WH, Zhang AS, Enns CA
The Journal of biological chemistry 2020 Mar 20;295(12):3906-3917
The Journal of biological chemistry 2020 Mar 20;295(12):3906-3917
Dual regulation of p53 by the ribosome maturation factor SBDS.
Hao Q, Wang J, Chen Y, Wang S, Cao M, Lu H, Zhou X
Cell death & disease 2020 Mar 20;11(3):197
Cell death & disease 2020 Mar 20;11(3):197
Regulation of the linear ubiquitination of STAT1 controls antiviral interferon signaling.
Zuo Y, Feng Q, Jin L, Huang F, Miao Y, Liu J, Xu Y, Chen X, Zhang H, Guo T, Yuan Y, Zhang L, Wang J, Zheng H
Nature communications 2020 Mar 2;11(1):1146
Nature communications 2020 Mar 2;11(1):1146
HNF-1a promotes pancreatic cancer growth and apoptosis resistance via its target gene PKLR.
Fan Z, Fan K, Deng S, Gong Y, Qian Y, Huang Q, Yang C, Cheng H, Jin K, Luo G, Liu C, Yu X
Acta biochimica et biophysica Sinica 2020 Mar 18;52(3):241-250
Acta biochimica et biophysica Sinica 2020 Mar 18;52(3):241-250
Alarmin HMGB1 Plays a Detrimental Role in Hippocampal Dysfunction Caused by Hypoxia-Ischemia Insult in Neonatal Mice: Evidence from the Application of the HMGB1 Inhibitor Glycyrrhizin.
Le K, Wu S, Chibaatar E, Ali AI, Guo Y
ACS chemical neuroscience 2020 Mar 18;11(6):979-993
ACS chemical neuroscience 2020 Mar 18;11(6):979-993
Identification of ALPPL2 as a Naive Pluripotent State-Specific Surface Protein Essential for Human Naive Pluripotency Regulation.
Bi Y, Tu Z, Zhang Y, Yang P, Guo M, Zhu X, Zhao C, Zhou J, Wang H, Wang Y, Gao S
Cell reports 2020 Mar 17;30(11):3917-3931.e5
Cell reports 2020 Mar 17;30(11):3917-3931.e5
TXNIP deficiency mitigates podocyte apoptosis via restraining the activation of mTOR or p38 MAPK signaling in diabetic nephropathy.
Song S, Qiu D, Wang Y, Wei J, Wu H, Wu M, Wang S, Zhou X, Shi Y, Duan H
Experimental cell research 2020 Mar 15;388(2):111862
Experimental cell research 2020 Mar 15;388(2):111862
Synergetic inhibition of daidzein and regular exercise on breast cancer in bearing-4T1 mice by regulating NK cells and apoptosis pathway.
Wang B, Xu H, Hu X, Ma W, Zhang J, Li Y, Yu M, Zhang Y, Li X, Ye X
Life sciences 2020 Mar 15;245:117387
Life sciences 2020 Mar 15;245:117387
Neuronal BIN1 Regulates Presynaptic Neurotransmitter Release and Memory Consolidation.
De Rossi P, Nomura T, Andrew RJ, Masse NY, Sampathkumar V, Musial TF, Sudwarts A, Recupero AJ, Le Metayer T, Hansen MT, Shim HN, Krause SV, Freedman DJ, Bindokas VP, Kasthuri N, Nicholson DA, Contractor A, Thinakaran G
Cell reports 2020 Mar 10;30(10):3520-3535.e7
Cell reports 2020 Mar 10;30(10):3520-3535.e7
HIF2-Induced Long Noncoding RNA RAB11B-AS1 Promotes Hypoxia-Mediated Angiogenesis and Breast Cancer Metastasis.
Niu Y, Bao L, Chen Y, Wang C, Luo M, Zhang B, Zhou M, Wang JE, Fang YV, Kumar A, Xing C, Wang Y, Luo W
Cancer research 2020 Mar 1;80(5):964-975
Cancer research 2020 Mar 1;80(5):964-975
Microcystins-LR induced apoptosis via S-nitrosylation of GAPDH in colorectal cancer cells.
Li K, Huang M, Xu P, Wang M, Ye S, Wang Q, Zeng S, Chen X, Gao W, Chen J, Zhang Q, Zhong Z, Sun Y, Liu Q
Ecotoxicology and environmental safety 2020 Mar 1;190:110096
Ecotoxicology and environmental safety 2020 Mar 1;190:110096
Ferulic acid isolated from propolis inhibits porcine parvovirus replication potentially through Bid-mediate apoptosis.
Ma X, Guo Z, Zhang Z, Li X, Wang X, Liu Y, Wang X
International immunopharmacology 2020 Jun;83:106379
International immunopharmacology 2020 Jun;83:106379
Histone demethylase KDM4A regulates adipogenic and osteogenic differentiation via epigenetic regulation of C/EBPα and canonical Wnt signaling.
Qi Q, Wang Y, Wang X, Yang J, Xie Y, Zhou J, Li X, Wang B
Cellular and molecular life sciences : CMLS 2020 Jun;77(12):2407-2421
Cellular and molecular life sciences : CMLS 2020 Jun;77(12):2407-2421
Reversing a model of Parkinson's disease with in situ converted nigral neurons.
Qian H, Kang X, Hu J, Zhang D, Liang Z, Meng F, Zhang X, Xue Y, Maimon R, Dowdy SF, Devaraj NK, Zhou Z, Mobley WC, Cleveland DW, Fu XD
Nature 2020 Jun;582(7813):550-556
Nature 2020 Jun;582(7813):550-556
MiR-153-3p induces immune dysregulation by inhibiting PELI1 expression in umbilical cord-derived mesenchymal stem cells in patients with systemic lupus erythematosus.
Li D, Li X, Duan M, Dou Y, Feng Y, Nan N, Zhang W
Autoimmunity 2020 Jun;53(4):201-209
Autoimmunity 2020 Jun;53(4):201-209
PAQR3 protects against oxygen-glucose deprivation/reperfusion-induced injury through the ERK signaling pathway in N2A cells.
Peng W, Mo X, Li L, Lu T, Hu Z
Journal of molecular histology 2020 Jun;51(3):307-315
Journal of molecular histology 2020 Jun;51(3):307-315
Esculetin Ameliorates Lipopolysaccharide-Induced Acute Lung Injury in Mice Via Modulation of the AKT/ERK/NF-κB and RORγt/IL-17 Pathways.
Lee HC, Liu FC, Tsai CN, Chou AH, Liao CC, Yu HP
Inflammation 2020 Jun;43(3):962-974
Inflammation 2020 Jun;43(3):962-974
Quercetin suppresses migration and invasion by targeting miR-146a/GATA6 axis in fibroblast-like synoviocytes of rheumatoid arthritis.
Zhao J, Chen B, Peng X, Wang C, Wang K, Han F, Xu J
Immunopharmacology and immunotoxicology 2020 Jun;42(3):221-227
Immunopharmacology and immunotoxicology 2020 Jun;42(3):221-227
Inhibition of miR-574-5p suppresses cell growth and metastasis and enhances chemosensitivity by targeting RNA binding protein QKI in cervical cancer cells.
Tong R, Zhang J, Wang C, Li Q, Wang L, Ju M
Naunyn-Schmiedeberg's archives of pharmacology 2020 Jun;393(6):951-966
Naunyn-Schmiedeberg's archives of pharmacology 2020 Jun;393(6):951-966
Human placenta derived mesenchymal stromal cells alleviate GVHD by promoting the generation of GSH and GST in PD-1+T cells.
Zhuoya W, Nannan Z, Aiping Z, Guoyan W, Menghua D, Jiashen Z, Yanlian X, Xiying L
Cellular immunology 2020 Jun;352:104083
Cellular immunology 2020 Jun;352:104083
Regulatory T cell is critical for interleukin-33-mediated neuroprotection against stroke.
Liu X, Hu R, Pei L, Si P, Wang C, Tian X, Wang X, Liu H, Wang B, Xia Z, Xu Y, Song B
Experimental neurology 2020 Jun;328:113233
Experimental neurology 2020 Jun;328:113233
SUMOylation of vascular endothelial growth factor receptor 2 inhibits the proliferation, migration, and angiogenesis signaling pathway in non-small cell lung cancer.
Wang M, Jiang X
Anti-cancer drugs 2020 Jun;31(5):492-499
Anti-cancer drugs 2020 Jun;31(5):492-499
Tizoxanide mitigates inflammatory response in LPS-induced neuroinflammation in microglia via restraining p38/MAPK pathway.
Li XW, He RZ, Li Y, Ruan ZF
European review for medical and pharmacological sciences 2020 Jun;24(11):6446-6454
European review for medical and pharmacological sciences 2020 Jun;24(11):6446-6454
Astrocyte elevated gene 1 (AEG-1) promotes anoikis resistance and metastasis by inducing autophagy in hepatocellular carcinoma.
Zhu HD, Liu L, Deng H, Li ZB, Sheng JQ, He XX, Tian DA, Li PY
Journal of cellular physiology 2020 Jun;235(6):5084-5095
Journal of cellular physiology 2020 Jun;235(6):5084-5095
Disregulation of Autophagy in the Transgenerational Cc2d1a Mouse Model of Autism.
Dana H, Bayramov KK, Delibaşı N, Tahtasakal R, Bayramov R, Hamurcu Z, Sener EF
Neuromolecular medicine 2020 Jun;22(2):239-249
Neuromolecular medicine 2020 Jun;22(2):239-249
The Activation of Heat-Shock Protein After Copper(II) and/or Arsenic(III)-Induced Imbalance of Homeostasis, Inflammatory Response in Chicken Rectum.
Yang X, Zhao H, Wang Y, Liu J, Guo M, Fei D, Mu M, Xing M
Biological trace element research 2020 Jun;195(2):613-623
Biological trace element research 2020 Jun;195(2):613-623
BRM-SWI/SNF chromatin remodeling complex enables functional telomeres by promoting co-expression of TRF2 and TRF1.
Wu S, Ge Y, Li X, Yang Y, Zhou H, Lin K, Zhang Z, Zhao Y
PLoS genetics 2020 Jun;16(6):e1008799
PLoS genetics 2020 Jun;16(6):e1008799
Sustained mitochondrial biogenesis is essential to maintain caloric restriction-induced beige adipocytes.
Mooli RGR, Mukhi D, Watt M, Edmunds L, Xie B, Capooci J, Reslink M, Eze C, Mills A, Stolz DB, Jurczak M, Ramakrishnan SK
Metabolism: clinical and experimental 2020 Jun;107:154225
Metabolism: clinical and experimental 2020 Jun;107:154225
Tolfenamic acid inhibits GSK-3β and PP2A mediated tau hyperphosphorylation in Alzheimer's disease models.
Zhang H, Wang X, Xu P, Ji X, Chi T, Liu P, Zou L
The journal of physiological sciences : JPS 2020 Jun 9;70(1):29
The journal of physiological sciences : JPS 2020 Jun 9;70(1):29
Highly expressed STAT1 contributes to the suppression of stemness properties in human paclitaxel-resistant ovarian cancer cells.
Wang F, Zhang L, Liu J, Zhang J, Xu G
Aging 2020 Jun 9;12(11):11042-11060
Aging 2020 Jun 9;12(11):11042-11060
Arsenic induces dysfunctional autophagy via dual regulation of mTOR pathway and Beclin1-Vps34/PI3K complex in MLTC-1 cells.
Liang C, Feng Z, Manthari RK, Wang C, Han Y, Fu W, Wang J, Zhang J
Journal of hazardous materials 2020 Jun 5;391:122227
Journal of hazardous materials 2020 Jun 5;391:122227
The GTPase Rab27b regulates the release, autophagic clearance, and toxicity of α-synuclein.
Underwood R, Wang B, Carico C, Whitaker RH, Placzek WJ, Yacoubian TA
The Journal of biological chemistry 2020 Jun 5;295(23):8005-8016
The Journal of biological chemistry 2020 Jun 5;295(23):8005-8016
BDH2 triggers ROS-induced cell death and autophagy by promoting Nrf2 ubiquitination in gastric cancer.
Liu JZ, Hu YL, Feng Y, Jiang Y, Guo YB, Liu YF, Chen X, Yang JL, Chen YY, Mao QS, Xue WJ
Journal of experimental & clinical cancer research : CR 2020 Jun 30;39(1):123
Journal of experimental & clinical cancer research : CR 2020 Jun 30;39(1):123
Enterovirus A71 Oncolysis of Malignant Gliomas.
Zhang X, Wang H, Sun Y, Qi M, Li W, Zhang Z, Zhang XE, Cui Z
Molecular therapy : the journal of the American Society of Gene Therapy 2020 Jun 3;28(6):1533-1546
Molecular therapy : the journal of the American Society of Gene Therapy 2020 Jun 3;28(6):1533-1546
Cytoplasmic PCNA is located in the actin belt and involved in osteoclast differentiation.
Tang D, Liu X, Chen K, Li Z, Dai Y, Xu J, Zhang HT, Gao X, Liu L
Aging 2020 Jun 27;12(13):13297-13317
Aging 2020 Jun 27;12(13):13297-13317
MiR-377-3p inhibits atherosclerosis-associated vascular smooth muscle cell proliferation and migration via targeting neuropilin2.
Wang H, Wei Z, Li H, Guan Y, Han Z, Wang H, Liu B
Bioscience reports 2020 Jun 26;40(6)
Bioscience reports 2020 Jun 26;40(6)
Molecular mechanism of targeted inhibition of HMGA2 via miRNAlet-7a in proliferation and metastasis of laryngeal squamous cell carcinoma.
Ma LJ, Wu J, Zhou E, Yin J, Xiao XP
Bioscience reports 2020 Jun 26;40(6)
Bioscience reports 2020 Jun 26;40(6)
Opening large-conductance potassium channels selectively induced cell death of triple-negative breast cancer.
Sizemore G, McLaughlin S, Newman M, Brundage K, Ammer A, Martin K, Pugacheva E, Coad J, Mattes MD, Yu HG
BMC cancer 2020 Jun 26;20(1):595
BMC cancer 2020 Jun 26;20(1):595
Enhanced autophagic retrograde axonal transport by dynein intermediate chain upregulation improves Aβ clearance and cognitive function in APP/PS1 double transgenic mice.
Zhou F, Xiong X, Li S, Liang J, Zhang X, Tian M, Li X, Gao M, Tang L, Li Y
Aging 2020 Jun 24;12(12):12142-12159
Aging 2020 Jun 24;12(12):12142-12159
L-3-n-butylphthalide attenuates inflammation response and brain edema in rat intracerebral hemorrhage model.
Zeng Z, Gong X, Hu Z
Aging 2020 Jun 21;12(12):11768-11780
Aging 2020 Jun 21;12(12):11768-11780
A Gold(I) Complex Containing an Oleanolic Acid Derivative as a Potential Anti-Ovarian-Cancer Agent by Inhibiting TrxR and Activating ROS-Mediated ERS.
Bian M, Sun Y, Liu Y, Xu Z, Fan R, Liu Z, Liu W
Chemistry (Weinheim an der Bergstrasse, Germany) 2020 Jun 2;26(31):7092-7108
Chemistry (Weinheim an der Bergstrasse, Germany) 2020 Jun 2;26(31):7092-7108
Excretory/secretory products of Angiostrongylus cantonensis fifth-stage larvae induce endoplasmic reticulum stress via the Sonic hedgehog pathway in mouse astrocytes.
Chen KY, Chen YJ, Cheng CJ, Jhan KY, Wang LC
Parasites & vectors 2020 Jun 18;13(1):317
Parasites & vectors 2020 Jun 18;13(1):317
Immune profiling reveals prognostic genes in high-grade serous ovarian cancer.
Wu Y, Xia L, Zhao P, Deng Y, Guo Q, Zhu J, Chen X, Ju X, Wu X
Aging 2020 Jun 16;12(12):11398-11415
Aging 2020 Jun 16;12(12):11398-11415
Neurotoxicity of aluminum oxide nanoparticles and their mechanistic role in dopaminergic neuron injury involving p53-related pathways.
Liu H, Zhang W, Fang Y, Yang H, Tian L, Li K, Lai W, Bian L, Lin B, Liu X, Xi Z
Journal of hazardous materials 2020 Jun 15;392:122312
Journal of hazardous materials 2020 Jun 15;392:122312
Cerenkov luminescence imaging is an effective preclinical tool for assessing colorectal cancer PD-L1 levels in vivo.
Zhao S, Pan W, Jiang H, Zhang R, Jiang H, Liang Z, Hu H
EJNMMI research 2020 Jun 15;10(1):64
EJNMMI research 2020 Jun 15;10(1):64
Mechanism of Heshouwuyin inhibiting the Cyt c/Apaf-1/Caspase-9/Caspase-3 pathway in spermatogenic cell apoptosis.
Wang H, Zhu J, Jiang L, Shan B, Xiao P, Ai J, Li N, Qi F, Niu S
BMC complementary medicine and therapies 2020 Jun 11;20(1):180
BMC complementary medicine and therapies 2020 Jun 11;20(1):180
Regulatory effects of Prohibitin 1 on proliferation and apoptosis of pulmonary arterial smooth muscle cells in monocrotaline-induced PAH rats.
Cao YY, Ba HX, Li Y, Tang SY, Luo ZQ, Li XH
Life sciences 2020 Jun 1;250:117548
Life sciences 2020 Jun 1;250:117548
Synergistic Effect of Benzethonium Chloride Combined with Endoxan against Hepatocellular Carcinoma in Rats through Targeting Apoptosis Signaling Pathway.
Abozaid OAR, Moawed FSM, Farrag MA, Kawara RSM
Asian Pacific journal of cancer prevention : APJCP 2020 Jun 1;21(6):1709-1716
Asian Pacific journal of cancer prevention : APJCP 2020 Jun 1;21(6):1709-1716
Fast and unbiased purification of RNA-protein complexes after UV cross-linking.
Urdaneta EC, Beckmann BM
Methods (San Diego, Calif.) 2020 Jun 1;178:72-82
Methods (San Diego, Calif.) 2020 Jun 1;178:72-82
Daucosterol linolenate from Sweet Potato Suppresses MCF7-Xenograft-Tumor Growth through Regulating PI3K/AKT Pathway.
Han B, Jiang L, Jiang P, Zhou D, Jia X, Li X, Ye X
Planta medica 2020 Jul;86(11):767-775
Planta medica 2020 Jul;86(11):767-775
A novel homozygous nonsense ZP1 variant causes human female infertility associated with empty follicle syndrome (EFS).
Xu Q, Zhu X, Maqsood M, Li W, Tong X, Kong S, Wang F, Liu X, Wei Z, Zhang Z, Zhu F, Cao Y, Bao J
Molecular genetics & genomic medicine 2020 Jul;8(7):e1269
Molecular genetics & genomic medicine 2020 Jul;8(7):e1269
Structural Basis of Human Helicase DDX21 in RNA Binding, Unwinding, and Antiviral Signal Activation.
Chen Z, Li Z, Hu X, Xie F, Kuang S, Zhan B, Gao W, Chen X, Gao S, Li Y, Wang Y, Qian F, Ding C, Gan J, Ji C, Xu XW, Zhou Z, Huang J, He HH, Li J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2020 Jul;7(14):2000532
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2020 Jul;7(14):2000532
A mitophagic response to iron overload-induced oxidative damage associated with the PINK1/Parkin pathway in pancreatic beta cells.
Zhang L, Hou L, Liu Z, Huang S, Meng Z, Liang L
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2020 Jul;60:126493
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2020 Jul;60:126493
lncRNA LA16c‑313D11.11 modulates the development of endometrial cancer by binding to and inhibiting microRNA‑205‑5p function and indirectly increasing PTEN activity.
Xin W, Zhao S, Han X, Zhao P, Yu H, Gao X, Li P, Wu Q, Ding J, Hua K
International journal of oncology 2020 Jul;57(1):355-363
International journal of oncology 2020 Jul;57(1):355-363
Matrix Metalloproteinase 11 as a Novel Tumor Promoter and Diagnostic and Prognostic Biomarker for Pancreatic Ductal Adenocarcinoma.
Zhang X, Lu J, Zhou L, You L, Liang Z, Guo J, Zhao Y
Pancreas 2020 Jul;49(6):812-821
Pancreas 2020 Jul;49(6):812-821
Characterization of red ginseng-drug interaction by CYP3A activity increased in high dose administration in mice.
Kim Y, Jo JJ, Cho P, Shrestha R, Kim KM, Ki SH, Song KS, Liu KH, Song IS, Kim JH, Lee JM, Lee S
Biopharmaceutics & drug disposition 2020 Jul;41(7):295-306
Biopharmaceutics & drug disposition 2020 Jul;41(7):295-306
HMGB1-induced aberrant autophagy contributes to insulin resistance in granulosa cells in PCOS.
Zhang C, Hu J, Wang W, Sun Y, Sun K
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jul;34(7):9563-9574
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jul;34(7):9563-9574
miR-196b-5p controls adipocyte differentiation and lipogenesis through regulating mTORC1 and TGF-β signaling.
Shi Y, Li F, Wang S, Wang C, Xie Y, Zhou J, Li X, Wang B
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jul;34(7):9207-9222
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jul;34(7):9207-9222
Presynaptic Caytaxin prevents apoptosis via deactivating DAPK1 in the acute phase of cerebral ischemic stroke.
Wang S, Chen K, Yu J, Wang X, Li Q, Lv F, Shen H, Pei L
Experimental neurology 2020 Jul;329:113303
Experimental neurology 2020 Jul;329:113303
miR-203a suppresses cell proliferation by targeting RING-finger protein 6 in colorectal cancer.
Miao J, Hou N, Yang W, Jiang Q, Xue W, Wang X, Zhang H, Xiong X, Wang L, Zhao L, Huang C
Anti-cancer drugs 2020 Jul;31(6):583-591
Anti-cancer drugs 2020 Jul;31(6):583-591
Stomatin-like protein-2 confers neuroprotection effect in oxygen-glucose deprivation/reoxygenation-injured neurons by regulating AMPK/Nrf2 signalling.
Wang M, Li C, Shi W
Journal of drug targeting 2020 Jul;28(6):600-608
Journal of drug targeting 2020 Jul;28(6):600-608
Protective effect of quercetin on rat testes against cadmium toxicity by alleviating oxidative stress and autophagy.
Wang J, Zhu H, Wang K, Yang Z, Liu Z
Environmental science and pollution research international 2020 Jul;27(20):25278-25286
Environmental science and pollution research international 2020 Jul;27(20):25278-25286
BMP7 is Downregulated in Lumbosacral Spinal Cord of Rat Embryos With Anorectal Malformation.
Yang Z, Li X, Jia H, Bai Y, Wang W
The Journal of surgical research 2020 Jul;251:202-210
The Journal of surgical research 2020 Jul;251:202-210
Targeted immunomodulation of inflammatory monocytes across the blood-brain barrier by curcumin-loaded nanoparticles delays the progression of experimental autoimmune encephalomyelitis.
Lu L, Qi S, Chen Y, Luo H, Huang S, Yu X, Luo Q, Zhang Z
Biomaterials 2020 Jul;245:119987
Biomaterials 2020 Jul;245:119987
AMPH1 functions as a tumour suppressor in ovarian cancer via the inactivation of PI3K/AKT pathway.
Chen Y, Cao W, Wang L, Zhong T
Journal of cellular and molecular medicine 2020 Jul;24(13):7652-7659
Journal of cellular and molecular medicine 2020 Jul;24(13):7652-7659
SIRT2 suppresses expression of inflammatory factors via Hsp90-glucocorticoid receptor signalling.
Sun K, Wang X, Fang N, Xu A, Lin Y, Zhao X, Nazarali AJ, Ji S
Journal of cellular and molecular medicine 2020 Jul;24(13):7439-7450
Journal of cellular and molecular medicine 2020 Jul;24(13):7439-7450
CUDC-907, a novel dual PI3K and HDAC inhibitor, in prostate cancer: Antitumour activity and molecular mechanism of action.
Hu C, Xia H, Bai S, Zhao J, Edwards H, Li X, Yang Y, Lyu J, Wang G, Zhan Y, Dong Y, Ge Y
Journal of cellular and molecular medicine 2020 Jul;24(13):7239-7253
Journal of cellular and molecular medicine 2020 Jul;24(13):7239-7253
The effect of lncRNA-ARAP1-AS2/ARAP1 on high glucose-induced cytoskeleton rearrangement and epithelial-mesenchymal transition in human renal tubular epithelial cells.
Li L, Xu L, Wen S, Yang Y, Li X, Fan Q
Journal of cellular physiology 2020 Jul;235(7-8):5787-5795
Journal of cellular physiology 2020 Jul;235(7-8):5787-5795
Reversal of prolonged obesity-associated cerebrovascular dysfunction by inhibiting microglial Tak1.
Shen Q, Chen Z, Zhao F, Pan S, Zhang T, Cheng X, Zhang L, Zhang S, Qi J, Li J, Cai D, Zhang G
Nature neuroscience 2020 Jul;23(7):832-841
Nature neuroscience 2020 Jul;23(7):832-841
LHPP inhibits hepatocellular carcinoma cell growth and metastasis.
Liao L, Duan D, Liu Y, Chen L
Cell cycle (Georgetown, Tex.) 2020 Jul;19(14):1846-1854
Cell cycle (Georgetown, Tex.) 2020 Jul;19(14):1846-1854
Melatonin protects against chronic stress-induced oxidative meiotic defects in mice MII oocytes by regulating SIRT1.
Guo Y, Sun J, Bu S, Li B, Zhang Q, Wang Q, Lai D
Cell cycle (Georgetown, Tex.) 2020 Jul;19(13):1677-1695
Cell cycle (Georgetown, Tex.) 2020 Jul;19(13):1677-1695
Human alkaline ceramidase 2 promotes the growth, invasion, and migration of hepatocellular carcinoma cells via sphingomyelin phosphodiesterase acid-like 3B.
Liu B, Xiao J, Dong M, Qiu Z, Jin J
Cancer science 2020 Jul;111(7):2259-2274
Cancer science 2020 Jul;111(7):2259-2274
Bisdemethoxycurcumin inhibits oxidative stress and antagonizes Alzheimer's disease by up-regulating SIRT1.
Xu Y, Hu R, He D, Zhou G, Wu H, Xu C, He B, Wu L, Wang Y, Chang Y, Ma R, Xie M, Xiao Z
Brain and behavior 2020 Jul;10(7):e01655
Brain and behavior 2020 Jul;10(7):e01655
Pathological mutations in PNKP trigger defects in DNA single-strand break repair but not DNA double-strand break repair.
Kalasova I, Hailstone R, Bublitz J, Bogantes J, Hofmann W, Leal A, Hanzlikova H, Caldecott KW
Nucleic acids research 2020 Jul 9;48(12):6672-6684
Nucleic acids research 2020 Jul 9;48(12):6672-6684
Integrative Proteomic Characterization of Human Lung Adenocarcinoma.
Xu JY, Zhang C, Wang X, Zhai L, Ma Y, Mao Y, Qian K, Sun C, Liu Z, Jiang S, Wang M, Feng L, Zhao L, Liu P, Wang B, Zhao X, Xie H, Yang X, Zhao L, Chang Y, Jia J, Wang X, Zhang Y, Wang Y, Yang Y, Wu Z, Yang L, Liu B, Zhao T, Ren S, Sun A, Zhao Y, Ying W, Wang F, Wang G, Zhang Y, Cheng S, Qin J, Qian X, Wang Y, Li J, He F, Xiao T, Tan M
Cell 2020 Jul 9;182(1):245-261.e17
Cell 2020 Jul 9;182(1):245-261.e17
SLC7A2 serves as a potential biomarker and therapeutic target for ovarian cancer.
Sun T, Bi F, Liu Z, Yang Q
Aging 2020 Jul 9;12(13):13281-13296
Aging 2020 Jul 9;12(13):13281-13296
Protective effect of miRNA-containing extracellular vesicles derived from mesenchymal stromal cells of old rats on renal function in chronic kidney disease.
Wang Y, Guo YF, Fu GP, Guan C, Zhang X, Yang DG, Shi YC
Stem cell research & therapy 2020 Jul 8;11(1):274
Stem cell research & therapy 2020 Jul 8;11(1):274
SNHG11 promotes cell proliferation in colorectal cancer by forming a positive regulatory loop with c-Myc.
Huang W, Dong S, Cha Y, Yuan X
Biochemical and biophysical research communications 2020 Jul 5;527(4):985-992
Biochemical and biophysical research communications 2020 Jul 5;527(4):985-992
The miR-1224-5p/TNS4/EGFR axis inhibits tumour progression in oesophageal squamous cell carcinoma.
Shi ZZ, Wang WJ, Chen YX, Fan ZW, Xie XF, Yang LY, Chang C, Cai Y, Hao JJ, Wang MR, Bai J
Cell death & disease 2020 Jul 30;11(7):597
Cell death & disease 2020 Jul 30;11(7):597
Transcriptome Analysis of Testes and Uterus: Reproductive Dysfunction Induced by Toxoplasma gondii in Mice.
Wang J, Liu T, Mahmmod YS, Yang Z, Tan J, Ren Z, Zhang X, Yang X, Zhang XX, Yuan ZG
Microorganisms 2020 Jul 28;8(8)
Microorganisms 2020 Jul 28;8(8)
NLRP3 inflammasome-mediated microglial pyroptosis is critically involved in the development of post-cardiac arrest brain injury.
Chang Y, Zhu J, Wang D, Li H, He Y, Liu K, Wang X, Peng Y, Pan S, Huang K
Journal of neuroinflammation 2020 Jul 23;17(1):219
Journal of neuroinflammation 2020 Jul 23;17(1):219
Innate Effector Systems in Primary Human Macrophages Sensitize Multidrug-Resistant Klebsiella pneumoniae to Antibiotics.
Rekha RS, Karadottir H, Ahmed S, Gudmundsson GH, Agerberth B, Bergman P
Infection and immunity 2020 Jul 21;88(8)
Infection and immunity 2020 Jul 21;88(8)
ZIC2 is downregulated and represses tumor growth via the regulation of STAT3 in breast cancer.
Liu ZH, Chen ML, Zhang Q, Zhang Y, An X, Luo YL, Liu XM, Liu SX, Liu Q, Yang T, Liu YM, Liu BL, Zhou AJ, Li MZ, Liu YJ, Liu ZX, Zhong Q
International journal of cancer 2020 Jul 15;147(2):505-518
International journal of cancer 2020 Jul 15;147(2):505-518
Impairment in dynein-mediated nuclear translocation by BICD2 C-terminal truncation leads to neuronal migration defect and human brain malformation.
Tsai MH, Cheng HY, Nian FS, Liu C, Chao NH, Chiang KL, Chen SF, Tsai JW
Acta neuropathologica communications 2020 Jul 14;8(1):106
Acta neuropathologica communications 2020 Jul 14;8(1):106
Genetic variants in m6A modification genes are associated with esophageal squamous-cell carcinoma in the Chinese population.
Yang N, Ying P, Tian J, Wang X, Mei S, Zou D, Peng X, Gong Y, Yang Y, Zhu Y, Ke J, Zhong R, Chang J, Miao X
Carcinogenesis 2020 Jul 10;41(6):761-768
Carcinogenesis 2020 Jul 10;41(6):761-768
Long non-coding RNA JPX correlates with poor prognosis and tumor progression in non-small-cell lung cancer by interacting with miR-145-5p and CCND2.
Jin M, Ren J, Luo M, You Z, Fang Y, Han Y, Li G, Liu H
Carcinogenesis 2020 Jul 10;41(5):634-645
Carcinogenesis 2020 Jul 10;41(5):634-645
Excessive Mg2+ Impairs Intestinal Homeostasis by Enhanced Production of Adenosine Triphosphate and Reactive Oxygen Species.
Hashizume O, Funato Y, Yamazaki D, Miki H
Antioxidants & redox signaling 2020 Jul 1;33(1):20-34
Antioxidants & redox signaling 2020 Jul 1;33(1):20-34
Carfilzomib inhibits the growth of lung adenocarcinoma via upregulation of Gadd45a expression.
Yang F, Liu WW, Chen H, Zhu J, Huang AH, Zhou F, Gan Y, Zhang YH, Ma L
Journal of Zhejiang University. Science. B 2020 Jan.;21(1):64-76
Journal of Zhejiang University. Science. B 2020 Jan.;21(1):64-76
Identification and characterization of c-raf from orange-spotted grouper (Epinephelus coioides).
Mo ZQ, Lai XL, Wang WT, Chen HP, He ZC, Han R, Wang JL, Luo XC, Li YW, Dan XM
Fish & shellfish immunology 2020 Jan;96:311-318
Fish & shellfish immunology 2020 Jan;96:311-318
MiR-203a-3p inhibits retinal angiogenesis and alleviates proliferative diabetic retinopathy in oxygen-induced retinopathy (OIR) rat model via targeting VEGFA and HIF-1α.
Han N, Xu H, Yu N, Wu Y, Yu L
Clinical and experimental pharmacology & physiology 2020 Jan;47(1):85-94
Clinical and experimental pharmacology & physiology 2020 Jan;47(1):85-94
Calycosin-7-O-β-D-glucoside attenuates myocardial ischemia-reperfusion injury by activating JAK2/STAT3 signaling pathway via the regulation of IL-10 secretion in mice.
Liu Y, Che G, Di Z, Sun W, Tian J, Ren M
Molecular and cellular biochemistry 2020 Jan;463(1-2):175-187
Molecular and cellular biochemistry 2020 Jan;463(1-2):175-187
MiR-183-5p protects rat hearts against myocardial ischemia/reperfusion injury through targeting VDAC1.
Lin D, Cui B, Ma J, Ren J
BioFactors (Oxford, England) 2020 Jan;46(1):83-93
BioFactors (Oxford, England) 2020 Jan;46(1):83-93
Decreased ALCAM expression and promoter hypermethylation is associated with preeclampsia.
Wei LL, Pan YS, Tang Q, Yang ZJ, Song WQ, Gao YF, Li J, Zhang L, Liu SG
Hypertension research : official journal of the Japanese Society of Hypertension 2020 Jan;43(1):13-22
Hypertension research : official journal of the Japanese Society of Hypertension 2020 Jan;43(1):13-22
High Expression of c-Met, PKCλ and ALDH1A3 Predicts a Poor Prognosis in Late-stage Breast Cancer.
Motomura H, Nozaki Y, Onaga C, Ozaki A, Tamori S, Shiina TA, Kanai S, Ohira C, Hara Y, Harada Y, Takasawa R, Hanawa T, Tanuma SI, Mano Y, Sato T, Sato K, Akimoto K
Anticancer research 2020 Jan;40(1):35-52
Anticancer research 2020 Jan;40(1):35-52
ALKATI interacts with c-Myc and promotes cancer stem cell-like properties in sarcoma.
Xu BS, Chen HY, Que Y, Xiao W, Zeng MS, Zhang X
Oncogene 2020 Jan;39(1):151-163
Oncogene 2020 Jan;39(1):151-163
MnTBAP inhibits bone loss in ovariectomized rats by reducing mitochondrial oxidative stress in osteoblasts.
Cao X, Luo D, Li T, Huang Z, Zou W, Wang L, Lian K, Lin D
Journal of bone and mineral metabolism 2020 Jan;38(1):27-37
Journal of bone and mineral metabolism 2020 Jan;38(1):27-37
LncRNA SNHG3 promotes cell proliferation and invasion through the miR-384/hepatoma-derived growth factor axis in breast cancer.
Ma Q, Qi X, Lin X, Li L, Chen L, Hu W
Human cell 2020 Jan;33(1):232-242
Human cell 2020 Jan;33(1):232-242
Hydrogen sulfide attenuates cigarette smoke-induced airway remodeling by upregulating SIRT1 signaling pathway.
Guan R, Wang J, Cai Z, Li Z, Wang L, Li Y, Xu J, Li D, Yao H, Liu W, Deng B, Lu W
Redox biology 2020 Jan;28:101356
Redox biology 2020 Jan;28:101356
Human mesenchymal stem cells-derived conditioned medium inhibits hypoxia-induced death of neonatal porcine islets by inducing autophagy.
Xu Y, Tan M, Ma X, Li H, He X, Chen Z, Tan Y, Nie W, Rong P, Wang W
Xenotransplantation 2020 Jan;27(1):e12556
Xenotransplantation 2020 Jan;27(1):e12556
LncRNA HOXA11-AS regulates calcium oxalate crystal-induced renal inflammation via miR-124-3p/MCP-1.
Li Y, Yan G, Zhang J, Chen W, Ding T, Yin Y, Li M, Zhu Y, Sun S, Yuan JH, Guo Z
Journal of cellular and molecular medicine 2020 Jan;24(1):238-249
Journal of cellular and molecular medicine 2020 Jan;24(1):238-249
Arsenic influences spermatogenesis by disorganizing the elongation of spermatids in adult male mice.
Han Y, Liang C, Manthari RK, Yu Y, Gao Y, Liu Y, Jiang S, Tikka C, Wang J, Zhang J
Chemosphere 2020 Jan;238:124650
Chemosphere 2020 Jan;238:124650
Endoplasmic reticulum stress regulates epithelial‑mesenchymal transition in human lens epithelial cells.
Zhou S, Yang J, Wang M, Zheng D, Liu Y
Molecular medicine reports 2020 Jan;21(1):173-180
Molecular medicine reports 2020 Jan;21(1):173-180
Effects of oral florfenicol on intestinal structure, function and microbiota in mice.
Yun S, Guo Y, Yang L, Zhang X, Shen W, Wang Z, Wen S, Zhao D, Wu H, Chen J, Sun Y, Duan Z
Archives of microbiology 2020 Jan;202(1):161-169
Archives of microbiology 2020 Jan;202(1):161-169
MicroRNA-138 inhibits tumor growth and enhances chemosensitivity in human cervical cancer by targeting H2AX.
Yuan M, Zhao S, Chen R, Wang G, Bie Y, Wu Q, Cheng J
Experimental and therapeutic medicine 2020 Jan;19(1):630-638
Experimental and therapeutic medicine 2020 Jan;19(1):630-638
REDD1 overexpression in oral squamous cell carcinoma may predict poor prognosis and correlates with high microvessel density.
Feng Y, Song K, Shang W, Chen L, Wang C, Pang B, Wang N
Oncology letters 2020 Jan;19(1):431-441
Oncology letters 2020 Jan;19(1):431-441
USP12 translocation maintains interferon antiviral efficacy by inhibiting CBP acetyltransferase activity.
Liu J, Jin L, Chen X, Yuan Y, Zuo Y, Miao Y, Feng Q, Zhang H, Huang F, Guo T, Zhang L, Zhu L, Qian F, Zhu C, Zheng H
PLoS pathogens 2020 Jan;16(1):e1008215
PLoS pathogens 2020 Jan;16(1):e1008215
The novel thioredoxin reductase inhibitor A-Z2 triggers intrinsic apoptosis and shows efficacy in the treatment of acute myeloid leukemia.
Zhang D, Liu Y, Luo Z, Chen Y, Xu A, Liang Y, Wu B, Tong X, Liu X, Shen H, Liu L, Wei Y, Zhou H, Liu Y, Zhou F
Free radical biology & medicine 2020 Jan;146:275-286
Free radical biology & medicine 2020 Jan;146:275-286
Osthole inhibits cell proliferation by regulating the TGF-β1/Smad/p38 signaling pathways in pulmonary arterial smooth muscle cells.
Yue Y, Li YQ, Fu S, Wu YT, Zhu L, Hua L, Lv JY, Li YL, Yang DL
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jan;121:109640
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jan;121:109640
Tandem mass tag (TMT) proteomic analysis of fetal lungs revealed differential expression of tight junction proteins in a rat model of congenital diaphragmatic hernia.
Li X, Liu H, Yu W, Liu X, Liu C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jan;121:109621
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jan;121:109621
Activation of CD137 signaling promotes neointimal formation by attenuating TET2 and transferrring from endothelial cell-derived exosomes to vascular smooth muscle cells.
Li B, Zang G, Zhong W, Chen R, Zhang Y, Yang P, Yan J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jan;121:109593
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jan;121:109593
LncRNA GAS5 exacerbates renal tubular epithelial fibrosis by acting as a competing endogenous RNA of miR-96-5p.
Wang W, Jia YJ, Yang YL, Xue M, Zheng ZJ, Wang L, Xue YM
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jan;121:109411
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jan;121:109411
Isolated Erythrocytosis Associated With 3 Novel Missense Mutations in the EGLN1 Gene.
Moore JA, Hubbi ME, Wang C, Wang Y, Luo W, Hofmann S, Rambally S
Journal of investigative medicine high impact case reports 2020 Jan-Dec;8:2324709620947256
Journal of investigative medicine high impact case reports 2020 Jan-Dec;8:2324709620947256
Acetyltransferase GCN5 regulates autophagy and lysosome biogenesis by targeting TFEB.
Wang Y, Huang Y, Liu J, Zhang J, Xu M, You Z, Peng C, Gong Z, Liu W
EMBO reports 2020 Jan 7;21(1):e48335
EMBO reports 2020 Jan 7;21(1):e48335
5-(3,4,5-trimethoxybenzoyl)-4-methyl-2-(p-tolyl) imidazol (BZML) targets tubulin and DNA to induce anticancer activity and overcome multidrug resistance in colorectal cancer cells.
Bai Z, Liu X, Guan Q, Ding N, Wei Q, Tong B, Zhao M, Zhang W, Ma L
Chemico-biological interactions 2020 Jan 5;315:108886
Chemico-biological interactions 2020 Jan 5;315:108886
Resveratrol targets PD-L1 glycosylation and dimerization to enhance antitumor T-cell immunity.
Verdura S, Cuyàs E, Cortada E, Brunet J, Lopez-Bonet E, Martin-Castillo B, Bosch-Barrera J, Encinar JA, Menendez JA
Aging 2020 Jan 4;12(1):8-34
Aging 2020 Jan 4;12(1):8-34
The tight junction protein TJP1 regulates the feeding-modulated hepatic circadian clock.
Liu Y, Zhang Y, Li T, Han J, Wang Y
Nature communications 2020 Jan 30;11(1):589
Nature communications 2020 Jan 30;11(1):589
Porphyromonas gingivalis triggers inflammatory responses in periodontal ligament cells by succinate-succinate dehydrogenase-HIF-1α axis.
Su W, Shi J, Zhao Y, Yan F, Lei L, Li H
Biochemical and biophysical research communications 2020 Jan 29;522(1):184-190
Biochemical and biophysical research communications 2020 Jan 29;522(1):184-190
Alisol A-24-acetate promotes glucose uptake via activation of AMPK in C2C12 myotubes.
Chen JX, Li HY, Li TT, Fu WC, Du X, Liu CH, Zhang W
BMC complementary medicine and therapies 2020 Jan 29;20(1):22
BMC complementary medicine and therapies 2020 Jan 29;20(1):22
Schnurri-3 regulates BMP9-induced osteogenic differentiation and angiogenesis of human amniotic mesenchymal stem cells through Runx2 and VEGF.
Li Y, Liu Z, Tang Y, Feng W, Zhao C, Liao J, Zhang C, Chen H, Ren Y, Dong S, Liu Y, Hu N, Huang W
Cell death & disease 2020 Jan 29;11(1):72
Cell death & disease 2020 Jan 29;11(1):72
Calcium relieves fluoride-induced bone damage through the PI3K/AKT pathway.
Wang J, Xu H, Cheng X, Yang J, Yan Z, Ma H, Zhao Y, Ommati MM, Manthari RK, Wang J
Food & function 2020 Jan 29;11(1):1155-1164
Food & function 2020 Jan 29;11(1):1155-1164
Graphene Oxide Promotes Cancer Metastasis through Associating with Plasma Membrane To Promote TGF-β Signaling-Dependent Epithelial-Mesenchymal Transition.
Zhu J, Li B, Xu M, Liu R, Xia T, Zhang Z, Xu Y, Liu S
ACS nano 2020 Jan 28;14(1):818-827
ACS nano 2020 Jan 28;14(1):818-827
GSPE alleviates renal fibrosis by inhibiting the activation of C3/ HMGB1/ TGF-β1 pathway.
Wang K, Wei H, Zhan J, Liang X, Zhang C, Liu Y, Xu G
Chemico-biological interactions 2020 Jan 25;316:108926
Chemico-biological interactions 2020 Jan 25;316:108926
An insertion mutation of ERBB2 enhances breast cancer cell growth and confers resistance to lapatinib through AKT signaling pathway.
Yang ZY, Yang L, Xu CW, Wang XJ, Lei L
Biology open 2020 Jan 24;9(1)
Biology open 2020 Jan 24;9(1)
miR-485 suppresses inflammation and proliferation of mesangial cells in an in vitro model of diabetic nephropathy by targeting NOX5.
Wu J, Lu K, Zhu M, Xie X, Ding Y, Shao X, Chen Y, Liu J, Xu M, Xu Y, Zhou J, Shen X, Zhu C
Biochemical and biophysical research communications 2020 Jan 22;521(4):984-990
Biochemical and biophysical research communications 2020 Jan 22;521(4):984-990
FAM60A, increased by Helicobacter pylori, promotes proliferation and suppresses apoptosis of gastric cancer cells by targeting the PI3K/AKT pathway.
Yao X, Liu D, Zhou L, Xie Y, Li Y
Biochemical and biophysical research communications 2020 Jan 22;521(4):1003-1009
Biochemical and biophysical research communications 2020 Jan 22;521(4):1003-1009
The Nuclear Matrix Protein SAFB Cooperates with Major Satellite RNAs to Stabilize Heterochromatin Architecture Partially through Phase Separation.
Huo X, Ji L, Zhang Y, Lv P, Cao X, Wang Q, Yan Z, Dong S, Du D, Zhang F, Wei G, Liu Y, Wen B
Molecular cell 2020 Jan 16;77(2):368-383.e7
Molecular cell 2020 Jan 16;77(2):368-383.e7
K562 cell-derived exosomes suppress the adhesive function of bone marrow mesenchymal stem cells via delivery of miR-711.
Jiang YH, Liu J, Lin J, Li SQ, Xu YM, Min QH, Zhong QH, Sun F, Li J, You XH, Liao KL, Qin TY, Zhao C, Huang B, Wang XZ
Biochemical and biophysical research communications 2020 Jan 15;521(3):584-589
Biochemical and biophysical research communications 2020 Jan 15;521(3):584-589
Fangchinoline derivatives induce cell cycle arrest and apoptosis in human leukemia cell lines via suppression of the PI3K/AKT and MAPK signaling pathway.
Yang J, Hu S, Wang C, Song J, Chen C, Fan Y, Ben-David Y, Pan W
European journal of medicinal chemistry 2020 Jan 15;186:111898
European journal of medicinal chemistry 2020 Jan 15;186:111898
Microglia P2X4R-BDNF signalling contributes to central sensitization in a recurrent nitroglycerin-induced chronic migraine model.
Long T, He W, Pan Q, Zhang S, Zhang D, Qin G, Chen L, Zhou J
The journal of headache and pain 2020 Jan 14;21(1):4
The journal of headache and pain 2020 Jan 14;21(1):4
DEF Cell-Derived Exosomal miR-148a-5p Promotes DTMUV Replication by Negative Regulating TLR3 Expression.
Guo H, Cheng A, Zhang X, Pan Y, Wang M, Huang J, Zhu D, Chen S, Liu M, Zhao X, Wu Y, Yang Q, Zhang S, Yu Y, Pan L, Tian B, Rehman MU, Chen X, Liu Y, Zhang L, Yin Z, Jing B, Jia R
Viruses 2020 Jan 14;12(1)
Viruses 2020 Jan 14;12(1)
Endogenous production of C-C motif chemokine ligand 2 by nasopharyngeal carcinoma cells drives radioresistance-associated metastasis.
Guo SS, Liu R, Wen YF, Liu LT, Yuan L, Li YX, Li Y, Hao WW, Peng JY, Chen DN, Tang QN, Sun XS, Guo L, Mo HY, Qian CN, Zeng MS, Bei JX, Sun SY, Chen QY, Tang LQ, Mai HQ
Cancer letters 2020 Jan 1;468:27-40
Cancer letters 2020 Jan 1;468:27-40
Schizandrin B Mitigates Rifampicin-Induced Liver Injury by Inhibiting Endoplasmic Reticulum Stress.
Cheng L, Yang Z, Sun Z, Zhang W, Ren Y, Wang M, Han X, Fei L, Zhao Y, Pan H, Xie J, Nie S
Biological & pharmaceutical bulletin 2020 Jan 1;43(1):145-152
Biological & pharmaceutical bulletin 2020 Jan 1;43(1):145-152
Regulation of the firing activity by PKA-PKC-Src family kinases in cultured neurons of hypothalamic arcuate nucleus.
Sun XD, Wang A, Ma P, Gong S, Tao J, Yu XM, Jiang X
Journal of neuroscience research 2020 Feb;98(2):384-403
Journal of neuroscience research 2020 Feb;98(2):384-403
PITPNC1 fuels radioresistance of rectal cancer by inhibiting reactive oxygen species production.
Tan Y, Shao R, Li J, Huang H, Wang Y, Zhang M, Cao J, Zhang J, Bu J
Annals of translational medicine 2020 Feb;8(4):126
Annals of translational medicine 2020 Feb;8(4):126
Chronic toxicity of methamphetamine: Oxidative remodeling of pulmonary arteries.
Liang LY, Wang MM, Liu M, Zhao W, Wang X, Shi L, Zhu MJ, Zhao YL, Liu L, Maurya P, Wang Y
Toxicology in vitro : an international journal published in association with BIBRA 2020 Feb;62:104668
Toxicology in vitro : an international journal published in association with BIBRA 2020 Feb;62:104668
Beta-Amyloid Increases the Expression Levels of Tid1 Responsible for Neuronal Cell Death and Amyloid Beta Production.
Zhou C, Taslima F, Abdelhamid M, Kim SW, Akatsu H, Michikawa M, Jung CG
Molecular neurobiology 2020 Feb;57(2):1099-1114
Molecular neurobiology 2020 Feb;57(2):1099-1114
Association between different levels of lipid metabolism‑related enzymes and fatty acid synthase in Wilms' tumor.
Wang X, Du G, Wu Y, Zhang Y, Guo F, Liu W, Wu R
International journal of oncology 2020 Feb;56(2):568-580
International journal of oncology 2020 Feb;56(2):568-580
BDNF-TrkB pathway mediates antidepressant-like roles of H2 S in diabetic rats via promoting hippocampal autophagy.
Liu HY, Wei HJ, Wu L, Liu SM, Tang YY, Zou W, Wang CY, Zhang P, Tang XQ
Clinical and experimental pharmacology & physiology 2020 Feb;47(2):302-312
Clinical and experimental pharmacology & physiology 2020 Feb;47(2):302-312
Transcription factor RUNX2 regulates epithelial‑mesenchymal transition and progression in renal cell carcinomas.
Liu B, Liu J, Yu H, Wang C, Kong C
Oncology reports 2020 Feb;43(2):609-616
Oncology reports 2020 Feb;43(2):609-616
Sirtuin 3 induces apoptosis and necroptosis by regulating mutant p53 expression in small‑cell lung cancer.
Tang X, Li Y, Liu L, Guo R, Zhang P, Zhang Y, Zhang Y, Zhao J, Su J, Sun L, Liu Y
Oncology reports 2020 Feb;43(2):591-600
Oncology reports 2020 Feb;43(2):591-600
Visfatin Exerts Immunotherapeutic Effects in Lipopolysaccharide-Induced Acute Lung Injury in Murine Model.
Luo Y, Pang XX, Ansari AR, Wu XT, Li HZ, Zhang ZW, Song H
Inflammation 2020 Feb;43(1):109-122
Inflammation 2020 Feb;43(1):109-122
Lactobacillus johnsonii L531 ameliorates enteritis via elimination of damaged mitochondria and suppression of SQSTM1-dependent mitophagy in a Salmonella infantis model of piglet diarrhea.
Xia B, Yu J, He T, Liu X, Su J, Wang M, Wang J, Zhu Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Feb;34(2):2821-2839
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Feb;34(2):2821-2839
Berberine inhibits proliferation and migration of colorectal cancer cells by downregulation of GRP78.
Gong C, Hu X, Xu Y, Yang J, Zong L, Wang C, Zhu J, Li Z, Lu D
Anti-cancer drugs 2020 Feb;31(2):141-149
Anti-cancer drugs 2020 Feb;31(2):141-149
RhoB is regulated by hypoxia and modulates metastasis in breast cancer.
Ju JA, Godet I, DiGiacomo JW, Gilkes DM
Cancer reports (Hoboken, N.J.) 2020 Feb;3(1):e1164
Cancer reports (Hoboken, N.J.) 2020 Feb;3(1):e1164
Polychlorinated biphenyl quinone promotes macrophage polarization to CD163+ cells through Nrf2 signaling pathway.
Liu J, Yang B, Wang Y, Wu Y, Fan B, Zhu S, Song E, Song Y
Environmental pollution (Barking, Essex : 1987) 2020 Feb;257:113587
Environmental pollution (Barking, Essex : 1987) 2020 Feb;257:113587
LncRNA HRCEG, regulated by HDAC1, inhibits cells proliferation and epithelial-mesenchymal-transition in gastric cancer.
Wu S, Wu E, Wang D, Niu Y, Yue H, Zhang D, Luo J, Chen R
Cancer genetics 2020 Feb;241:25-33
Cancer genetics 2020 Feb;241:25-33
Mitochondrial respiratory chain damage and mitochondrial fusion disorder are involved in liver dysfunction of fluoride-induced mice.
Wang HW, Liu J, Wei SS, Zhao WP, Zhu SQ, Zhou BH
Chemosphere 2020 Feb;241:125099
Chemosphere 2020 Feb;241:125099
Effects of Starvation on Antioxidant-Related Signaling Molecules, Oxidative Stress, and Autophagy in Juvenile Chinese Perch Skeletal Muscle.
Wu P, Wang A, Cheng J, Chen L, Pan Y, Li H, Zhang Q, Zhang J, Chu W, Zhang J
Marine biotechnology (New York, N.Y.) 2020 Feb;22(1):81-93
Marine biotechnology (New York, N.Y.) 2020 Feb;22(1):81-93
Involvement of neurotrophic signaling in doxorubicin-induced cardiotoxicity.
Liao D, Zhang C, Liu N, Cao L, Wang C, Feng Q, Yao D, Long M, Jiang P
Experimental and therapeutic medicine 2020 Feb;19(2):1129-1135
Experimental and therapeutic medicine 2020 Feb;19(2):1129-1135
1,3-Dicaffeoylquinic acid targeting 14-3-3 tau suppresses human breast cancer cell proliferation and metastasis through IL6/JAK2/PI3K pathway.
Zhou Y, Fu X, Guan Y, Gong M, He K, Huang B
Biochemical pharmacology 2020 Feb;172:113752
Biochemical pharmacology 2020 Feb;172:113752
Discovery of a first-in-class EZH2 selective degrader.
Ma A, Stratikopoulos E, Park KS, Wei J, Martin TC, Yang X, Schwarz M, Leshchenko V, Rialdi A, Dale B, Lagana A, Guccione E, Parekh S, Parsons R, Jin J
Nature chemical biology 2020 Feb;16(2):214-222
Nature chemical biology 2020 Feb;16(2):214-222
PDE9 inhibition promotes proliferation of neural stem cells via cGMP-PKG pathway following oxygen-glucose deprivation/reoxygenation injury in vitro.
Huan X, Oumei C, Hongmei Q, Junxia Y, Xiaojiao M, Qingsong J
Neurochemistry international 2020 Feb;133:104630
Neurochemistry international 2020 Feb;133:104630
Predictive Value of Pin1 in Cervical Low-Grade Squamous Intraepithelial Lesions and Inhibition of Pin1 Exerts Potent Anticancer Activity against Human Cervical Cancer.
Guo YT, Lu Y, Jia YY, Qu HN, Qi D, Wang XQ, Song PY, Jin XS, Xu WH, Dong Y, Liang YY, Quan CS
Aging and disease 2020 Feb;11(1):44-59
Aging and disease 2020 Feb;11(1):44-59
Ferrostatin-1 mitigates cognitive impairment of epileptic rats by inhibiting P38 MAPK activation.
Ye Q, Zeng C, Luo C, Wu Y
Epilepsy & behavior : E&B 2020 Feb;103(Pt A):106670
Epilepsy & behavior : E&B 2020 Feb;103(Pt A):106670
The Combination of Fasting, Acute Resistance Exercise, and Protein Ingestion Led to Different Responses of Autophagy Markers in Gastrocnemius and Liver Samples.
Pinto AP, Vieira TS, Marafon BB, Batitucci G, Cabrera EMB, da Rocha AL, Kohama EB, Rodrigues KCC, de Moura LP, Pauli JR, Cintra DE, Ropelle ER, de Freitas EC, da Silva ASR
Nutrients 2020 Feb 28;12(3)
Nutrients 2020 Feb 28;12(3)
MicroRNA-377-3p alleviates IL-1β-caused chondrocyte apoptosis and cartilage degradation in osteoarthritis in part by downregulating ITGA6.
Tu Y, Ma T, Wen T, Yang T, Xue L, Cai M, Wang F, Guan M, Xue H
Biochemical and biophysical research communications 2020 Feb 26;523(1):46-53
Biochemical and biophysical research communications 2020 Feb 26;523(1):46-53
RNA Binding Protein RNPC1 Suppresses the Stemness of Human Endometrial Cancer Cells via Stabilizing MST1/2 mRNA.
Wu X, Wang Y, Zhong W, Cheng H, Tian Z
Medical science monitor : international medical journal of experimental and clinical research 2020 Feb 23;26:e921389
Medical science monitor : international medical journal of experimental and clinical research 2020 Feb 23;26:e921389
Targeting UBE4A Revives Viperin Protein in Epithelium to Enhance Host Antiviral Defense.
Yuan Y, Miao Y, Qian L, Zhang Y, Liu C, Liu J, Zuo Y, Feng Q, Guo T, Zhang L, Chen X, Jin L, Huang F, Zhang H, Zhang W, Li W, Xu G, Zheng H
Molecular cell 2020 Feb 20;77(4):734-747.e7
Molecular cell 2020 Feb 20;77(4):734-747.e7
Polyphyllin VII attenuated RANKL-induced osteoclast differentiation via inhibiting of TRAF6/c-Src/PI3K pathway and ROS production.
Zhou L, Song H, Zhang Y, Ren Z, Li M, Fu Q
BMC musculoskeletal disorders 2020 Feb 19;21(1):112
BMC musculoskeletal disorders 2020 Feb 19;21(1):112
GRWD1 promotes cell proliferation and migration in non-small cell lung cancer by activating the Notch pathway.
Wang Q, Ren H, Xu Y, Jiang J, Wudu M, Liu Z, Su H, Jiang X, Zhang Y, Zhang B, Qiu X
Experimental cell research 2020 Feb 15;387(2):111806
Experimental cell research 2020 Feb 15;387(2):111806
Network Pharmacology-Based Prediction and Verification of Qingluo Tongbi Formula to Reduce Liver Toxicity of Tripterygium wilfordii via UGT2B7 in Endoplasmic Reticulum.
Li M, Wang J, Fu L, Lu Y, Xu J, Zhou L, Zhu H, Fang L, Feng Z, Xie T, Zhou X
Medical science monitor : international medical journal of experimental and clinical research 2020 Feb 15;26:e920376
Medical science monitor : international medical journal of experimental and clinical research 2020 Feb 15;26:e920376
PRL/microRNA-183/IRS1 Pathway Regulates Milk Fat Metabolism in Cow Mammary Epithelial Cells.
Jiao P, Yuan Y, Zhang M, Sun Y, Wei C, Xie X, Zhang Y, Wang S, Chen Z, Wang X
Genes 2020 Feb 13;11(2)
Genes 2020 Feb 13;11(2)
Doublecortin undergo nucleocytoplasmic transport via the RanGTPase signaling to promote glioma progression.
Ayanlaja AA, Ji G, Wang J, Gao Y, Cheng B, Kanwore K, Zhang L, Xiong Y, Kambey PA, Gao D
Cell communication and signaling : CCS 2020 Feb 12;18(1):24
Cell communication and signaling : CCS 2020 Feb 12;18(1):24
Curcumin Protects Human Trophoblast HTR8/SVneo Cells from H2O2-Induced Oxidative Stress by Activating Nrf2 Signaling Pathway.
Qi L, Jiang J, Zhang J, Zhang L, Wang T
Antioxidants (Basel, Switzerland) 2020 Feb 1;9(2)
Antioxidants (Basel, Switzerland) 2020 Feb 1;9(2)
Protective effect of resveratrol on obesity-related osteoarthritis via alleviating JAK2/STAT3 signaling pathway is independent of SOCS3.
Jiang M, He J, Gu H, Yang Y, Huang Y, Xu X, Liu L
Toxicology and applied pharmacology 2020 Feb 1;388:114871
Toxicology and applied pharmacology 2020 Feb 1;388:114871
PTP1B promotes macrophage activation by regulating the NF-κB pathway in alcoholic liver injury.
Yang L, Sun YY, Liu YR, Yin NN, Bu FT, Yu HX, Du XS, Li J, Huang C
Toxicology letters 2020 Feb 1;319:11-21
Toxicology letters 2020 Feb 1;319:11-21
Silencing of DsbA-L gene impairs the PPARγ agonist function of improving insulin resistance in a high-glucose cell model.
Zhou X, Li JQ, Wei LJ, He MZ, Jia J, Zhang JY, Wang SS, Feng L
Journal of Zhejiang University. Science. B 2020 Dec.;21(12):990-998
Journal of Zhejiang University. Science. B 2020 Dec.;21(12):990-998
SUMOylation of Pdia3 exacerbates proinsulin misfolding and ER stress in pancreatic beta cells.
Li N, Luo X, Yu Q, Yang P, Chen Z, Wang X, Jiang J, Xu J, Gong Q, Eizirik DL, Zhou Z, Zhao J, Xiong F, Zhang S, Wang CY
Journal of molecular medicine (Berlin, Germany) 2020 Dec;98(12):1795-1807
Journal of molecular medicine (Berlin, Germany) 2020 Dec;98(12):1795-1807
LXA4 protects against hypoxic-ischemic damage in neonatal rats by reducing the inflammatory response via the IκB/NF-κB pathway.
Zhu JJ, Yu BY, Fu CC, He MZ, Zhu JH, Chen BW, Zheng YH, Chen SQ, Fu XQ, Li PJ, Lin ZL
International immunopharmacology 2020 Dec;89(Pt B):107095
International immunopharmacology 2020 Dec;89(Pt B):107095
Annexin A3 upregulates the infiltrated neutrophil-lymphocyte ratio to remodel the immune microenvironment in hepatocellular carcinoma.
Zhu Q, Pan QZ, Zhong AL, Hu H, Zhao JJ, Tang Y, Hu WM, Li M, Weng DS, Chen MY, Ma G, Xia JC
International immunopharmacology 2020 Dec;89(Pt A):107139
International immunopharmacology 2020 Dec;89(Pt A):107139
Angiopoietin-like protein 4 promotes very-low-density lipoprotein assembly and secretion in bovine hepatocytes in vitro.
Kong Y, Zhao C, Huang Y, Liu Y, Liu S, Guo Y, Li M, Xu T, Zhao B, Wang J
IUBMB life 2020 Dec;72(12):2710-2721
IUBMB life 2020 Dec;72(12):2710-2721
Quercetin alleviates neonatal hypoxic-ischemic brain injury by inhibiting microglia-derived oxidative stress and TLR4-mediated inflammation.
Le K, Song Z, Deng J, Peng X, Zhang J, Wang L, Zhou L, Bi H, Liao Z, Feng Z
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2020 Dec;69(12):1201-1213
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2020 Dec;69(12):1201-1213
Knockdown of eukaryotic translation initiation factor 5A2 enhances the therapeutic efficiency of doxorubicin in hepatocellular carcinoma cells by triggering lethal autophagy.
Tang Y, Chen K, Luan X, Zhang J, Liu R, Zheng X, Xie S, Ke H, Zhang X, Chen W
International journal of oncology 2020 Dec;57(6):1368-1380
International journal of oncology 2020 Dec;57(6):1368-1380
Nobiletin Ameliorates NLRP3 Inflammasome-Mediated Inflammation Through Promoting Autophagy via the AMPK Pathway.
Wang H, Guo Y, Qiao Y, Zhang J, Jiang P
Molecular neurobiology 2020 Dec;57(12):5056-5068
Molecular neurobiology 2020 Dec;57(12):5056-5068
An antiviral drug-resistant mutant of hepatitis B virus with high replication capacity in association with a large in-frame deletion in the preS1 region of viral surface gene.
Wang T, Qin Y, Zhang J, Li X, Tong S, Zhao W, Zhang J
Virus genes 2020 Dec;56(6):677-686
Virus genes 2020 Dec;56(6):677-686
Intratunical injection of human urine-derived stem cells derived exosomes prevents fibrosis and improves erectile function in a rat model of Peyronie's disease.
Yang Q, Chen W, Han D, Zhang C, Xie Y, Sun X, Liu G, Deng C
Andrologia 2020 Dec;52(11):e13831
Andrologia 2020 Dec;52(11):e13831
MMP7 damages the integrity of the renal tubule epithelium by activating MMP2/9 during ischemia-reperfusion injury.
Hu Q, Lan J, Liang W, Chen Y, Chen B, Liu Z, Xiong Y, Zhong Z, Wang Y, Ye Q
Journal of molecular histology 2020 Dec;51(6):685-700
Journal of molecular histology 2020 Dec;51(6):685-700
Down-Regulated CUEDC2 Increases GDNF Expression by Stabilizing CREB Through Reducing Its Ubiquitination in Glioma.
Liu XF, Tang CX, Zhang L, Tong SY, Wang Y, Abdulrahman AA, Ji GQ, Gao Y, Gao DS, Zhang BL
Neurochemical research 2020 Dec;45(12):2915-2925
Neurochemical research 2020 Dec;45(12):2915-2925
Aberrant expression of miRNA-192-5p contributes to N,N-dimethylformamide-induced hepatic apoptosis.
Zhang Z, Zhu W, Liu Z, Liu Y, Chang C, Jiang H, Li R, Xiao Y, Chen W, Hu Q, Wang Q
Journal of applied toxicology : JAT 2020 Dec;40(12):1683-1693
Journal of applied toxicology : JAT 2020 Dec;40(12):1683-1693
Histone demethylase JHDM2A regulates H3K9 dimethylation in response to arsenic-induced DNA damage and repair in normal human liver cells.
Zhang AL, Tang SF, Yang Y, Li CZ, Ding XJ, Zhao H, Wang JH, Yang GH, Li J
Journal of applied toxicology : JAT 2020 Dec;40(12):1661-1672
Journal of applied toxicology : JAT 2020 Dec;40(12):1661-1672
Inhibition of ACSL4 attenuates ferroptotic damage after pulmonary ischemia-reperfusion.
Xu Y, Li X, Cheng Y, Yang M, Wang R
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Dec;34(12):16262-16275
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Dec;34(12):16262-16275
PFOS-induced placental cell growth inhibition is partially mediated by lncRNA H19 through interacting with miR-19a and miR-19b.
Li J, Quan XJ, Chen G, Hong JW, Wang Q, Xu LL, Wang BH, Yu ZH, Yu HM
Chemosphere 2020 Dec;261:127640
Chemosphere 2020 Dec;261:127640
Molecular identification, tissue distribution and in vitro functional analysis of growth hormone and its receptors in red-spotted grouper (Epinephelus akaara).
Yuan X, Lin Y, Qin J, Zhang Y, Yang G, Cai R, Liao Z, Sun C, Li W
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 2020 Dec;250:110488
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 2020 Dec;250:110488
Inhibition of CACNA1H can alleviate endoplasmic reticulum stress and reduce myocardial cell apoptosis caused by myocardial infarction.
Wang MX, Liu X, Li JM, Liu L, Lu W, Chen GC
European review for medical and pharmacological sciences 2020 Dec;24(24):12887-12895
European review for medical and pharmacological sciences 2020 Dec;24(24):12887-12895
FABP4 inhibitor attenuates inflammation and endoplasmic reticulum stress of islet in leptin receptor knockout rats.
Yao F, Jiang DD, Guo WH, Guo LS, Gao MM, Bai Y, Wang X, Zhang LS
European review for medical and pharmacological sciences 2020 Dec;24(24):12808-12820
European review for medical and pharmacological sciences 2020 Dec;24(24):12808-12820
Polarization of ADAM17-driven EGFR signalling in electric field-guided collective migration of epidermal sheets.
Jia N, Liu J, Zhu G, Liang Y, Wang Y, Wang W, Chen Y, Yang J, Zhang W, Zhang J
Journal of cellular and molecular medicine 2020 Dec;24(23):14073-14085
Journal of cellular and molecular medicine 2020 Dec;24(23):14073-14085
The proinflammatory cytokines IL-1β and TNF-α modulate corneal epithelial wound healing through p16Ink4a suppressing STAT3 activity.
Wang X, Zhang S, Dong M, Li Y, Zhou Q, Yang L
Journal of cellular physiology 2020 Dec;235(12):10081-10093
Journal of cellular physiology 2020 Dec;235(12):10081-10093
miR-448-3p alleviates diabetic vascular dysfunction by inhibiting endothelial-mesenchymal transition through DPP-4 dysregulation.
Guan GY, Wei N, Song T, Zhao C, Sun Y, Pan RX, Zhang LL, Xu YY, Dai YM, Han H
Journal of cellular physiology 2020 Dec;235(12):10024-10036
Journal of cellular physiology 2020 Dec;235(12):10024-10036
Inhibition of p38 MAPK regulates epileptic severity by decreasing expression levels of A1R and ENT1.
Zhou X, Chen Q, Huang H, Zhang J, Wang J, Chen Y, Peng Y, Zhang H, Zeng J, Feng Z, Xu Z
Molecular medicine reports 2020 Dec;22(6):5348-5357
Molecular medicine reports 2020 Dec;22(6):5348-5357
Effect of TFAM on ATP content in tachypacing primary cultured cardiomyocytes and atrial fibrillation patients.
Liu Y, Zhao Y, Tang R, Jiang X, Wang Y, Gu T
Molecular medicine reports 2020 Dec;22(6):5105-5112
Molecular medicine reports 2020 Dec;22(6):5105-5112
IGFBP‑rP1‑silencing promotes hypoxia‑induced angiogenic potential of choroidal endothelial cells via the RAF/MEK/ERK signaling pathway.
Zhu S, Wang H, Zhang Z, Ma M, Zheng Z, Xu X, Sun T
Molecular medicine reports 2020 Dec;22(6):4837-4847
Molecular medicine reports 2020 Dec;22(6):4837-4847
Pseudolaric acid B induces apoptosis in human rhabdomyosarcoma RD cells.
Liu C, Wang F, Wang B, Wu T, Wang Y, Huo W, Zhang S, Su Y, Liu J, Liu Y, Yu J
Oncology letters 2020 Dec;20(6):358
Oncology letters 2020 Dec;20(6):358
A Combination of BRD4 and HDAC3 Inhibitors Synergistically Suppresses Glioma Stem Cell Growth by Blocking GLI1/IL6/STAT3 Signaling Axis.
Wang Q, Jia S, Wang D, Chen X, Kalvakolanu DV, Zheng H, Wei X, Wen N, Liang H, Guo B, Zhang L
Molecular cancer therapeutics 2020 Dec;19(12):2542-2553
Molecular cancer therapeutics 2020 Dec;19(12):2542-2553
Resveratrol improves meat quality, muscular antioxidant capacity, lipid metabolism and fiber type composition of intrauterine growth retarded pigs.
Cheng K, Yu C, Li Z, Li S, Yan E, Song Z, Zhang H, Zhang L, Wang T
Meat science 2020 Dec;170:108237
Meat science 2020 Dec;170:108237
Polymethoxyflavones from citrus inhibited gastric cancer cell proliferation through inducing apoptosis by upregulating RARβ, both in vitro and in vivo.
Wang Y, Chen Y, Zhang H, Chen J, Cao J, Chen Q, Li X, Sun C
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2020 Dec;146:111811
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2020 Dec;146:111811
Cannabinoid receptor subtype influence on neuritogenesis in human SH-SY5Y cells.
Lyons EL, Leone-Kabler S, Kovach AL, Thomas BF, Howlett AC
Molecular and cellular neurosciences 2020 Dec;109:103566
Molecular and cellular neurosciences 2020 Dec;109:103566
Andrographolide exerts anti-inflammatory effects in Mycobacterium tuberculosis-infected macrophages by regulating the Notch1/Akt/NF-κB axis.
He W, Sun J, Zhang Q, Li Y, Fu Y, Zheng Y, Jiang X
Journal of leukocyte biology 2020 Dec;108(6):1747-1764
Journal of leukocyte biology 2020 Dec;108(6):1747-1764
Structural and Functional Characterization of Host FHL1 Protein Interaction with Hypervariable Domain of Chikungunya Virus nsP3 Protein.
Lukash T, Agback T, Dominguez F, Shiliaev N, Meshram C, Frolova EI, Agback P, Frolov I
Journal of virology 2020 Dec 9;95(1)
Journal of virology 2020 Dec 9;95(1)
β-Elemene enhances radiosensitivity in non-small-cell lung cancer by inhibiting epithelial-mesenchymal transition and cancer stem cell traits via Prx-1/NF-kB/iNOS signaling pathway.
Zou K, Li Z, Zhang Y, Mu L, Chen M, Wang R, Deng W, Zou L, Liu J
Aging 2020 Dec 9;13(2):2575-2592
Aging 2020 Dec 9;13(2):2575-2592
Condensation of Rubisco into a proto-pyrenoid in higher plant chloroplasts.
Atkinson N, Mao Y, Chan KX, McCormick AJ
Nature communications 2020 Dec 9;11(1):6303
Nature communications 2020 Dec 9;11(1):6303
Exploration of the Effects of Substrate Stiffness on Biological Responses of Neural Cells and Their Mechanisms.
Zhang C, Tan Y, Feng J, Huang C, Liu B, Fan Z, Xu B, Lu T
ACS omega 2020 Dec 8;5(48):31115-31125
ACS omega 2020 Dec 8;5(48):31115-31125
circ_2858 Helps Blood-Brain Barrier Disruption by Increasing VEGFA via Sponging miR-93-5p during Escherichia coli Meningitis.
Yang R, Chen J, Xu B, Yang B, Fu J, Xiao S, Tan C, Chen H, Wang X
Molecular therapy. Nucleic acids 2020 Dec 4;22:708-721
Molecular therapy. Nucleic acids 2020 Dec 4;22:708-721
Metabotropic glutamate receptor 5 regulates synaptic plasticity in a chronic migraine rat model through the PKC/NR2B signal.
Niu Y, Zeng X, Zhao L, Zhou Y, Qin G, Zhang D, Fu Q, Zhou J, Chen L
The journal of headache and pain 2020 Dec 4;21(1):139
The journal of headache and pain 2020 Dec 4;21(1):139
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) membrane (M) protein inhibits type I and III interferon production by targeting RIG-I/MDA-5 signaling.
Zheng Y, Zhuang MW, Han L, Zhang J, Nan ML, Zhan P, Kang D, Liu X, Gao C, Wang PH
Signal transduction and targeted therapy 2020 Dec 28;5(1):299
Signal transduction and targeted therapy 2020 Dec 28;5(1):299
TRIM24 promotes stemness and invasiveness of glioblastoma cells via activating Sox2 expression.
Zhang LH, Yin YH, Chen HZ, Feng SY, Liu JL, Chen L, Fu WL, Sun GC, Yu XG, Xu DG
Neuro-oncology 2020 Dec 18;22(12):1797-1808
Neuro-oncology 2020 Dec 18;22(12):1797-1808
RIPK1 Distinctly Regulates Yersinia-Induced Inflammatory Cell Death, PANoptosis.
Malireddi RKS, Kesavardhana S, Karki R, Kancharana B, Burton AR, Kanneganti TD
ImmunoHorizons 2020 Dec 11;4(12):789-796
ImmunoHorizons 2020 Dec 11;4(12):789-796
Ubiquitination of RIPK1 regulates its activation mediated by TNFR1 and TLRs signaling in distinct manners.
Li X, Zhang M, Huang X, Liang W, Li G, Lu X, Li Y, Pan H, Shi L, Zhu H, Qian L, Shan B, Yuan J
Nature communications 2020 Dec 11;11(1):6364
Nature communications 2020 Dec 11;11(1):6364
Exploring the mechanism of cisplatin resistance by transcriptome sequencing and reversing the chemoresistance by autophagy inhibition in small cell lung cancer.
Ma K, Li S, Huo X, Guo M, Du X, Li C, Liu X, Lv J, Chen Z
Biochemical and biophysical research communications 2020 Dec 10;533(3):474-480
Biochemical and biophysical research communications 2020 Dec 10;533(3):474-480
Podocyte-derived extracellular vesicles mediate renal proximal tubule cells dedifferentiation via microRNA-221 in diabetic nephropathy.
Su H, Qiao J, Hu J, Li Y, Lin J, Yu Q, Zhen J, Ma Q, Wang Q, Lv Z, Wang R
Molecular and cellular endocrinology 2020 Dec 1;518:111034
Molecular and cellular endocrinology 2020 Dec 1;518:111034
PhospholipaseCγ1/calcium-dependent membranous localization of Gsdmd-N drives endothelial pyroptosis, contributing to lipopolysaccharide-induced fatal outcome.
Liu H, Tang D, Zhou X, Yang X, Chen AF
American journal of physiology. Heart and circulatory physiology 2020 Dec 1;319(6):H1482-H1495
American journal of physiology. Heart and circulatory physiology 2020 Dec 1;319(6):H1482-H1495
Effects of taraxasterol against ethanol and high-fat diet-induced liver injury by regulating TLR4/MyD88/NF-κB and Nrf2/HO-1 signaling pathways.
Li Z, Lian Y, Wei R, Jin L, Cao H, Zhao T, Ma X, Zhong M, Gao Y, Zhang K
Life sciences 2020 Dec 1;262:118546
Life sciences 2020 Dec 1;262:118546
NPY stimulates cholesterol synthesis acutely by activating the SREBP2-HMGCR pathway through the Y1 and Y5 receptors in murine hepatocytes.
Chen F, Zhou Y, Yang K, Shen M, Wang Y
Life sciences 2020 Dec 1;262:118478
Life sciences 2020 Dec 1;262:118478
Prostaglandin I2 mediates weak vasodilatation in human placental microvessels.
Feng X, Zhang Y, Zhang Y, Yang X, Man D, Lu L, Xu T, Liu Y, Yang C, Li H, Qi L, Su H, Zhou X, Xu Z
Biology of reproduction 2020 Dec 1;103(6):1229-1237
Biology of reproduction 2020 Dec 1;103(6):1229-1237
HOTAIR promotes paclitaxel resistance by regulating CHEK1 in ovarian cancer.
Jiang J, Wang S, Wang Z, Cai J, Han L, Xie L, Han Q, Wang W, Zhang Y, He X, Yang C
Cancer chemotherapy and pharmacology 2020 Aug;86(2):295-305
Cancer chemotherapy and pharmacology 2020 Aug;86(2):295-305
Ginsenoside Rk3 alleviated DSS-induced ulcerative colitis by protecting colon barrier and inhibiting NLRP3 inflammasome pathway.
Tian M, Ma P, Zhang Y, Mi Y, Fan D
International immunopharmacology 2020 Aug;85:106645
International immunopharmacology 2020 Aug;85:106645
Metformin inhibits extracellular matrix accumulation, inflammation and proliferation of mesangial cells in diabetic nephropathy by regulating H19/miR-143-3p/TGF-β1 axis.
Xu J, Xiang P, Liu L, Sun J, Ye S
The Journal of pharmacy and pharmacology 2020 Aug;72(8):1101-1109
The Journal of pharmacy and pharmacology 2020 Aug;72(8):1101-1109
GOLPH3 Regulates Exosome miRNA Secretion in Glioma Cells.
Hu P, Wang K, Zhou D, Wang L, Zhao M, Wang W, Zhang Y, Liu Y, Yu R, Zhou X
Journal of molecular neuroscience : MN 2020 Aug;70(8):1257-1266
Journal of molecular neuroscience : MN 2020 Aug;70(8):1257-1266
Metabolomic profiling reveals similar cytotoxic effects and protective functions of quercetin during deoxynivalenol- and 15-acetyl deoxynivalenol-induced cell apoptosis.
Yang YX, Yu S, Jia BX, Liu N, Wu A
Toxicology in vitro : an international journal published in association with BIBRA 2020 Aug;66:104838
Toxicology in vitro : an international journal published in association with BIBRA 2020 Aug;66:104838
All-Trans Retinoic Acid Exerts Neuroprotective Effects in Amyotrophic Lateral Sclerosis-Like Tg (SOD1*G93A)1Gur Mice.
Zhu Y, Liu Y, Yang F, Chen W, Jiang J, He P, Jiang S, Li M, Xu R
Molecular neurobiology 2020 Aug;57(8):3603-3615
Molecular neurobiology 2020 Aug;57(8):3603-3615
Exopolysaccharide from Cryptococcus heimaeyensis S20 induces autophagic cell death in non-small cell lung cancer cells via ROS/p38 and ROS/ERK signalling.
Hao Y, Huang Y, Chen J, Li J, Yuan Y, Wang M, Han L, Xin X, Wang H, Lin D, Peng F, Yu F, Zheng C, Shen C
Cell proliferation 2020 Aug;53(8):e12869
Cell proliferation 2020 Aug;53(8):e12869
Role of Zinc Sulphate in Immune Regulation in Artemisia annua Pollen-challenged P815 Mastocytoma Cells.
Yang FX, Hou L, Wen WL, Shen XL, Feng NY, Ma RX, Yin S
Immunological investigations 2020 Aug;49(6):622-631
Immunological investigations 2020 Aug;49(6):622-631
Exogenous spermine attenuates myocardial fibrosis in diabetic cardiomyopathy by inhibiting endoplasmic reticulum stress and the canonical Wnt signaling pathway.
Hu J, Lu X, Zhang X, Shao X, Wang Y, Chen J, Zhao B, Li S, Xu C, Wei C
Cell biology international 2020 Aug;44(8):1660-1670
Cell biology international 2020 Aug;44(8):1660-1670
Setosphapyrone C and D accelerate macrophages cholesterol efflux by promoting LXRα/ABCA1 pathway.
Li T, Yin J, Ji Y, Lin P, Li Y, Yang Z, Hu S, Wang J, Zhang B, Koshti S, Wang J, Ji C, Guo S
Archives of pharmacal research 2020 Aug;43(8):788-797
Archives of pharmacal research 2020 Aug;43(8):788-797
Thymidine phosphorylase promotes angiogenesis and tumour growth in intrahepatic cholangiocarcinoma.
Li S, Yang H, Li K, Fan G, Deng L, Xu C
Cell biochemistry and function 2020 Aug;38(6):743-752
Cell biochemistry and function 2020 Aug;38(6):743-752
Downregulation of miR-140-5p affects the pathogenesis of HSCR by targeting EGR2.
Du G, Wang X, Wu Y, Zhang Y, Liu W, Wu R
Pediatric surgery international 2020 Aug;36(8):883-890
Pediatric surgery international 2020 Aug;36(8):883-890
Inhibition of the facilitative sugar transporters (GLUTs) by tea extracts and catechins.
Ni D, Ai Z, Munoz-Sandoval D, Suresh R, Ellis PR, Yuqiong C, Sharp PA, Butterworth PJ, Yu Z, Corpe CP
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Aug;34(8):9995-10010
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Aug;34(8):9995-10010
Lnc00462717 regulates the permeability of the blood-brain tumor barrier through interaction with PTBP1 to inhibit the miR-186-5p/Occludin signaling pathway.
Zhang C, Zhang X, Wang J, Di F, Xue Y, Lin X, Zhang Y, Zhang H, Zhang Z, Gu Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Aug;34(8):9941-9958
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Aug;34(8):9941-9958
USP30 sets a trigger threshold for PINK1-PARKIN amplification of mitochondrial ubiquitylation.
Rusilowicz-Jones EV, Jardine J, Kallinos A, Pinto-Fernandez A, Guenther F, Giurrandino M, Barone FG, McCarron K, Burke CJ, Murad A, Martinez A, Marcassa E, Gersch M, Buckmelter AJ, Kayser-Bricker KJ, Lamoliatte F, Gajbhiye A, Davis S, Scott HC, Murphy E, England K, Mortiboys H, Komander D, Trost M, Kessler BM, Ioannidis S, Ahlijanian MK, Urbé S, Clague MJ
Life science alliance 2020 Aug;3(8)
Life science alliance 2020 Aug;3(8)
Pseudorabies virus infection inhibits stress granules formation via dephosphorylating eIF2α.
Xu S, Chen D, Chen D, Hu Q, Zhou L, Ge X, Han J, Guo X, Yang H
Veterinary microbiology 2020 Aug;247:108786
Veterinary microbiology 2020 Aug;247:108786
Protective effect of exogenous hydrogen sulfide on diaphragm muscle fibrosis in streptozotocin-induced diabetic rats.
Yang R, Jia Q, Li Y, Mehmood S
Experimental biology and medicine (Maywood, N.J.) 2020 Aug;245(14):1280-1289
Experimental biology and medicine (Maywood, N.J.) 2020 Aug;245(14):1280-1289
Cell cycle exit during bortezomib-induced osteogenic differentiation of mesenchymal stem cells was mediated by Xbp1s-upregulated p21Cip1 and p27Kip1.
Zhang D, Fan R, Lei L, Lei L, Wang Y, Lv N, Chen P, Williamson RA, Wang B, Hu J
Journal of cellular and molecular medicine 2020 Aug;24(16):9428-9438
Journal of cellular and molecular medicine 2020 Aug;24(16):9428-9438
Salvianic acid A alleviates chronic alcoholic liver disease by inhibiting HMGB1 translocation via down-regulating BRD4.
Lan Y, Yan R, Shan W, Chu J, Sun R, Wang R, Zhao Y, Wang Z, Zhang N, Yao J
Journal of cellular and molecular medicine 2020 Aug;24(15):8518-8531
Journal of cellular and molecular medicine 2020 Aug;24(15):8518-8531
Septin4 regulates endoplasmic reticulum stress and apoptosis in melatonin‑induced osteoblasts.
Tao L, Zhao S, Tao Z, Wen K, Zhou S, Da W, Zhu Y
Molecular medicine reports 2020 Aug;22(2):1179-1186
Molecular medicine reports 2020 Aug;22(2):1179-1186
Overexpression of negative regulator of ubiquitin-like proteins 1 (NUB1) inhibits proliferation and invasion of gastric cancer cells through upregulation of p27Kip1 and inhibition of epithelial-mesenchymal transition.
Zhang D, Wu P, Zhang Z, An W, Zhang C, Pan S, Tan Y, Xu H
Pathology, research and practice 2020 Aug;216(8):153002
Pathology, research and practice 2020 Aug;216(8):153002
Overexpression of B7-H4 promotes renal cell carcinoma progression by recruiting tumor-associated neutrophils via upregulation of CXCL8.
Li A, Zhang N, Zhao Z, Chen Y, Zhang L
Oncology letters 2020 Aug;20(2):1535-1544
Oncology letters 2020 Aug;20(2):1535-1544
Hsa-miR-425-5p promotes tumor growth and metastasis by activating the CTNND1-mediated β-catenin pathway and EMT in colorectal cancer.
Liu D, Zhang H, Cui M, Chen C, Feng Y
Cell cycle (Georgetown, Tex.) 2020 Aug;19(15):1917-1927
Cell cycle (Georgetown, Tex.) 2020 Aug;19(15):1917-1927
Catalase is required for peroxisome maintenance during adipogenesis.
Nitta Y, Muraoka-Hirayama S, Sakurai K
Biochimica et biophysica acta. Molecular and cell biology of lipids 2020 Aug;1865(8):158726
Biochimica et biophysica acta. Molecular and cell biology of lipids 2020 Aug;1865(8):158726
Targeting G6PD reverses paclitaxel resistance in ovarian cancer by suppressing GSTP1.
Feng Q, Li X, Sun W, Sun M, Li Z, Sheng H, Xie F, Zhang S, Shan C
Biochemical pharmacology 2020 Aug;178:114092
Biochemical pharmacology 2020 Aug;178:114092
Localization of ZIP14 and ZIP8 in HIBCPP Cells.
Morgan SE, Schroten H, Ishikawa H, Zhao N
Brain sciences 2020 Aug 8;10(8)
Brain sciences 2020 Aug 8;10(8)
Reelin Promotes Cisplatin Resistance by Induction of Epithelial-Mesenchymal Transition via p38/GSK3β/Snail Signaling in Non-Small Cell Lung Cancer.
Li JM, Yang F, Li J, Yuan WQ, Wang H, Luo YQ
Medical science monitor : international medical journal of experimental and clinical research 2020 Aug 7;26:e925298
Medical science monitor : international medical journal of experimental and clinical research 2020 Aug 7;26:e925298
STIM1-mediated calcium influx controls antifungal immunity and the metabolic function of non-pathogenic Th17 cells.
Kahlfuss S, Kaufmann U, Concepcion AR, Noyer L, Raphael D, Vaeth M, Yang J, Pancholi P, Maus M, Muller J, Kozhaya L, Khodadadi-Jamayran A, Sun Z, Shaw P, Unutmaz D, Stathopulos PB, Feist C, Cameron SB, Turvey SE, Feske S
EMBO molecular medicine 2020 Aug 7;12(8):e11592
EMBO molecular medicine 2020 Aug 7;12(8):e11592
Selective Translation of Cell Fate Regulators Mediates Tolerance to Broad Oncogenic Stress.
Cai EY, Kufeld MN, Schuster S, Arora S, Larkin M, Germanos AA, Hsieh AC, Beronja S
Cell stem cell 2020 Aug 6;27(2):270-283.e7
Cell stem cell 2020 Aug 6;27(2):270-283.e7
Development of a Cationic Amphiphilic Helical Peptidomimetic (B18L) As A Novel Anti-Cancer Drug Lead.
Lyu Y, Kopcho S, Alvarez FA, Okeoma BC, Okeoma CM
Cancers 2020 Aug 28;12(9)
Cancers 2020 Aug 28;12(9)
Hippuric Acid Promotes Renal Fibrosis by Disrupting Redox Homeostasis via Facilitation of NRF2-KEAP1-CUL3 Interactions in Chronic Kidney Disease.
Sun B, Wang X, Liu X, Wang L, Ren F, Wang X, Leng X
Antioxidants (Basel, Switzerland) 2020 Aug 25;9(9)
Antioxidants (Basel, Switzerland) 2020 Aug 25;9(9)
Cotargeting of Mitochondrial Complex I and Bcl-2 Shows Antileukemic Activity against Acute Myeloid Leukemia Cells Reliant on Oxidative Phosphorylation.
Liu F, Kalpage HA, Wang D, Edwards H, Hüttemann M, Ma J, Su Y, Carter J, Li X, Polin L, Kushner J, Dzinic SH, White K, Wang G, Taub JW, Ge Y
Cancers 2020 Aug 24;12(9)
Cancers 2020 Aug 24;12(9)
α-Mangostin, a Dietary Xanthone, Exerts Protective Effects on Cisplatin-Induced Renal Injury via PI3K/Akt and JNK Signaling Pathways in HEK293 Cells.
Li Q, Yan XT, Zhao LC, Ren S, He YF, Liu WC, Wang Z, Li XD, Jiang S, Li W
ACS omega 2020 Aug 18;5(32):19960-19967
ACS omega 2020 Aug 18;5(32):19960-19967
Tetrandrine enhances glucocorticoid receptor translocation possibly via inhibition of P-glycoprotein in daunorubicin-resistant human T lymphoblastoid leukemia cells.
Xu W, Wang X, Chen S, Wu H, Tanaka S, Onda K, Sugiyama K, Yamada H, Hirano T
European journal of pharmacology 2020 Aug 15;881:173232
European journal of pharmacology 2020 Aug 15;881:173232
Bcl2 inhibitor ABT737 reverses the Warburg effect via the Sirt3-HIF1α axis to promote oxidative stress-induced apoptosis in ovarian cancer cells.
Dong D, Dong Y, Fu J, Lu S, Yuan C, Xia M, Sun L
Life sciences 2020 Aug 15;255:117846
Life sciences 2020 Aug 15;255:117846
Lactobacillus johnsonii L531 Ameliorates Escherichia coli-Induced Cell Damage via Inhibiting NLRP3 Inflammasome Activity and Promoting ATG5/ATG16L1-Mediated Autophagy in Porcine Mammary Epithelial Cells.
Zou YJ, Xu JJ, Wang X, Zhu YH, Wu Q, Wang JF
Veterinary sciences 2020 Aug 14;7(3)
Veterinary sciences 2020 Aug 14;7(3)
Plakoglobin is involved in cytoskeletal rearrangement of podocytes under the regulation of UCH-L1.
Fang Y, Li F, Qi C, Mao X, Xu Y, Zhao Z, Wu H, Zhang Z
Biochemical and biophysical research communications 2020 Aug 13;529(1):112-118
Biochemical and biophysical research communications 2020 Aug 13;529(1):112-118
Flavagline synthetic derivative induces senescence in glioblastoma cancer cells without being toxic to healthy astrocytes.
Harmouch E, Seitlinger J, Chaddad H, Ubeaud-Sequier G, Barths J, Saidu S, Désaubry L, Grandemange S, Massfelder T, Fuhrmann G, Fioretti F, Dontenwill M, Benkirane-Jessel N, Idoux-Gillet Y
Scientific reports 2020 Aug 13;10(1):13750
Scientific reports 2020 Aug 13;10(1):13750
Acetylation of Cytidine Residues Boosts HIV-1 Gene Expression by Increasing Viral RNA Stability.
Tsai K, Jaguva Vasudevan AA, Martinez Campos C, Emery A, Swanstrom R, Cullen BR
Cell host & microbe 2020 Aug 12;28(2):306-312.e6
Cell host & microbe 2020 Aug 12;28(2):306-312.e6
Cultivation of Hair Matrix Cells from Cashmere Goat Skins and Exemplified Applications.
Ma S, Wang L, Zong B, Wang Y, Wang X, Shi Y, Yang Y, Chen Y
Animals : an open access journal from MDPI 2020 Aug 12;10(8)
Animals : an open access journal from MDPI 2020 Aug 12;10(8)
The Small Molecule P7C3-A20 Exerts Neuroprotective Effects in a Hypoxic-ischemic Encephalopathy Model via Activation of PI3K/AKT/GSK3β Signaling.
Bai J, Zeng S, Zhu J, Fu C, He M, Zhu J, Chen S, Fu X, Li P, Lin Z
Neuroscience 2020 Aug 10;441:197-208
Neuroscience 2020 Aug 10;441:197-208
TMT-based proteomics analysis reveals the protective effects of Xuefu Zhuyu decoction in a rat model of traumatic brain injury.
Zhou D, Liu J, Hang Y, Li T, Li P, Guo S, Liu T, Xia Z, Wang Y
Journal of ethnopharmacology 2020 Aug 10;258:112826
Journal of ethnopharmacology 2020 Aug 10;258:112826
Lignans from Schisandra chinensis ameliorate alcohol and CCl4-induced long-term liver injury and reduce hepatocellular degeneration via blocking ETBR.
Xu JB, Gao GC, Yuan MJ, Huang X, Zhou HY, Zhang Y, Zheng YX, Wu Z, Feng JM, Wu JM
Journal of ethnopharmacology 2020 Aug 10;258:112813
Journal of ethnopharmacology 2020 Aug 10;258:112813
Role of ion channels in chronic intermittent hypoxia-induced atrial remodeling in rats.
Zhang K, Ma Z, Song C, Duan X, Yang Y, Li G
Life sciences 2020 Aug 1;254:117797
Life sciences 2020 Aug 1;254:117797
TLR4 knockout upregulates the expression of Mfn2 and PGC-1α in a high-fat diet and ischemia-reperfusion mice model of liver injury.
Zhang C, Jia Y, Liu B, Wang G, Zhang Y
Life sciences 2020 Aug 1;254:117762
Life sciences 2020 Aug 1;254:117762
Comparative analysis of two brine shrimps revealed differential expression pattern and functional characterization of CK2α under bacterial stimulation from different geographical distribution.
Wang Z, Hou Q, Wan K, Zhang R, Dong L, Zhang D, Yin H
Fish & shellfish immunology 2020 Apr;99:631-640
Fish & shellfish immunology 2020 Apr;99:631-640
Fangjihuangqi Decoction inhibits MDA-MB-231 cell invasion in vitro and decreases tumor growth and metastasis in triple-negative breast cancer xenografts tumor zebrafish model.
Guo Y, Fan Y, Pei X
Cancer medicine 2020 Apr;9(7):2564-2578
Cancer medicine 2020 Apr;9(7):2564-2578
Berberine combined with cyclosporine A alleviates acute graft-versus-host disease in murine models.
Wang M, Zhang J, Zhao H, Wan D, Jiang Z
International immunopharmacology 2020 Apr;81:106205
International immunopharmacology 2020 Apr;81:106205
Long non-coding RNA LOC100133669 promotes cell proliferation in oesophageal squamous cell carcinoma.
Guan Z, Wang Y, Wang Y, Liu X, Wang Y, Zhang W, Chi X, Dong Y, Liu X, Shao S, Zhan Q
Cell proliferation 2020 Apr;53(4):e12750
Cell proliferation 2020 Apr;53(4):e12750
Retinoid X receptor α (RXRα)-mediated erythroid-2-related factor-2 (NRF2) inactivation contributes to N,N-dimethylformamide (DMF)-induced oxidative stress in HL-7702 and HuH6 cells.
Jiang H, Li R, Zhang Z, Chang C, Liu Y, Liu Z, He Q, Wang Q
Journal of applied toxicology : JAT 2020 Apr;40(4):470-482
Journal of applied toxicology : JAT 2020 Apr;40(4):470-482
The Potential Role of PKA/CREB Signaling Pathway Concerned with Gastrodin Administration on Methamphetamine-Induced Conditioned Place Preference Rats and SH-SY5Y Cell Line.
Yang GM, Li L, Xue FL, Ma CL, Zeng XF, Zhao YN, Zhang DX, Yu Y, Yan QW, Zhou YQ, Hong SJ, Li LH
Neurotoxicity research 2020 Apr;37(4):926-935
Neurotoxicity research 2020 Apr;37(4):926-935
Virus analog decreases estradiol secretion in FSH-treated human ovarian granulosa cells.
Fang Y, Wang B, Lyu S, Zhang K, Cheng Q, Zhu Y
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 2020 Apr;36(4):346-350
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 2020 Apr;36(4):346-350
The deletion of mutant SOD1 via CRISPR/Cas9/sgRNA prolongs survival in an amyotrophic lateral sclerosis mouse model.
Duan W, Guo M, Yi L, Liu Y, Li Z, Ma Y, Zhang G, Liu Y, Bu H, Song X, Li C
Gene therapy 2020 Apr;27(3-4):157-169
Gene therapy 2020 Apr;27(3-4):157-169
MiR-129-5p protects against myocardial ischemia-reperfusion injury via targeting HMGB1.
Chen ZX, He D, Mo QW, Xie LP, Liang JR, Liu L, Fu WJ
European review for medical and pharmacological sciences 2020 Apr;24(8):4440-4450
European review for medical and pharmacological sciences 2020 Apr;24(8):4440-4450
Targeting STAT3 enhances NDV-induced immunogenic cell death in prostate cancer cells.
Wang X, Shao X, Gu L, Jiang K, Wang S, Chen J, Fang J, Guo X, Yuan M, Shi J, Ding C, Meng S, Xu Q
Journal of cellular and molecular medicine 2020 Apr;24(7):4286-4297
Journal of cellular and molecular medicine 2020 Apr;24(7):4286-4297
GLL398, an oral selective estrogen receptor degrader (SERD), blocks tumor growth in xenograft breast cancer models.
Guo S, Zhang C, Mottamal M, Hossain A, Liu J, Wang G
Breast cancer research and treatment 2020 Apr;180(2):359-368
Breast cancer research and treatment 2020 Apr;180(2):359-368
IL-29 promoted obesity-induced inflammation and insulin resistance.
Lin TY, Chiu CJ, Kuan CH, Chen FH, Shen YC, Wu CH, Hsu YH
Cellular & molecular immunology 2020 Apr;17(4):369-379
Cellular & molecular immunology 2020 Apr;17(4):369-379
NEK2 induces autophagy-mediated bortezomib resistance by stabilizing Beclin-1 in multiple myeloma.
Xia J, He Y, Meng B, Chen S, Zhang J, Wu X, Zhu Y, Shen Y, Feng X, Guan Y, Kuang C, Guo J, Lei Q, Wu Y, An G, Li G, Qiu L, Zhan F, Zhou W
Molecular oncology 2020 Apr;14(4):763-778
Molecular oncology 2020 Apr;14(4):763-778
A novel Sprouty4-ERK1/2-Wnt/β-catenin regulatory loop in marrow stromal progenitor cells controls osteogenic and adipogenic differentiation.
Tian L, Xiao H, Li M, Wu X, Xie Y, Zhou J, Zhang X, Wang B
Metabolism: clinical and experimental 2020 Apr;105:154189
Metabolism: clinical and experimental 2020 Apr;105:154189
Myxovirus resistance (Mx) gene and its differential expression regulated by three type I and two type II IFNs in mandarin fish, Siniperca chuatsi.
Li L, Chen SN, Laghari ZA, Huo HJ, Hou J, Huang L, Li N, Nie P
Developmental and comparative immunology 2020 Apr;105:103604
Developmental and comparative immunology 2020 Apr;105:103604
p53-mediated control of aspartate-asparagine homeostasis dictates LKB1 activity and modulates cell survival.
Deng L, Yao P, Li L, Ji F, Zhao S, Xu C, Lan X, Jiang P
Nature communications 2020 Apr 9;11(1):1755
Nature communications 2020 Apr 9;11(1):1755
A Combination of Formic Acid and Monolaurin Attenuates Enterotoxigenic Escherichia coli Induced Intestinal Inflammation in Piglets by Inhibiting the NF-κB/MAPK Pathways with Modulation of Gut Microbiota.
Ren C, Wang Y, Lin X, Song H, Zhou Q, Xu W, Shi K, Chen J, Song J, Chen F, Zhang S, Guan W
Journal of agricultural and food chemistry 2020 Apr 8;68(14):4155-4165
Journal of agricultural and food chemistry 2020 Apr 8;68(14):4155-4165
Synergistic Neuroprotective Effect of Endogenously-Produced Hydroxytyrosol and Synaptic Vesicle Proteins on Pheochromocytoma Cell Line Against Salsolinol.
Manzoor R, Rasool A, Ahmed M, Kaleem U, Duru LN, Ma H, Deng Y
Molecules (Basel, Switzerland) 2020 Apr 8;25(7)
Molecules (Basel, Switzerland) 2020 Apr 8;25(7)
Interaction between PHB2 and Enterovirus A71 VP1 Induces Autophagy and Affects EV-A71 Infection.
Su W, Huang S, Zhu H, Zhang B, Wu X
Viruses 2020 Apr 8;12(4)
Viruses 2020 Apr 8;12(4)
Anti-neuroinflammatory effects of dimethylaminomylide (DMAMCL, i.e., ACT001) are associated with attenuating the NLRP3 inflammasome in MPTP-induced Parkinson disease in mice.
Liu Q, Guo X, Huang Z, He Q, Zhu D, Zhang S, Peng Z, Che Y, Feng X
Behavioural brain research 2020 Apr 6;383:112539
Behavioural brain research 2020 Apr 6;383:112539
MicroRNA-574-5p in gastric cancer cells promotes angiogenesis by targeting protein tyrosine phosphatase non-receptor type 3 (PTPN3).
Zhang S, Zhang R, Xu R, Shang J, He H, Yang Q
Gene 2020 Apr 5;733:144383
Gene 2020 Apr 5;733:144383
Effect of fluoride on osteocyte-driven osteoclastic differentiation.
Jiang N, Guo F, Xu W, Zhang Z, Jin H, Shi L, Zhang X, Gao J, Xu H
Toxicology 2020 Apr 30;436:152429
Toxicology 2020 Apr 30;436:152429
Caspase-6 Is a Key Regulator of Innate Immunity, Inflammasome Activation, and Host Defense.
Zheng M, Karki R, Vogel P, Kanneganti TD
Cell 2020 Apr 30;181(3):674-687.e13
Cell 2020 Apr 30;181(3):674-687.e13
Decreased ZNF750 promotes angiogenesis in a paracrine manner via activating DANCR/miR-4707-3p/FOXC2 axis in esophageal squamous cell carcinoma.
Bi Y, Guo S, Xu X, Kong P, Cui H, Yan T, Ma Y, Cheng Y, Chen Y, Liu X, Zhang L, Cheng C, Xu E, Qian Y, Yang J, Song B, Li H, Wang F, Hu X, Liu X, Niu X, Zhai Y, Liu J, Li Y, Cheng X, Cui Y
Cell death & disease 2020 Apr 27;11(4):296
Cell death & disease 2020 Apr 27;11(4):296
Cold atmospheric plasma induces GSDME-dependent pyroptotic signaling pathway via ROS generation in tumor cells.
Yang X, Chen G, Yu KN, Yang M, Peng S, Ma J, Qin F, Cao W, Cui S, Nie L, Han W
Cell death & disease 2020 Apr 27;11(4):295
Cell death & disease 2020 Apr 27;11(4):295
4β-Hydroxywithanolide E from Goldenberry (Whole Fruits of Physalis peruviana L.) as a Promising Agent against Chronic Obstructive Pulmonary Disease.
Yang WJ, Chen XM, Wang SQ, Hu HX, Cheng XP, Xu LT, Ren DM, Wang XN, Zhao BB, Lou HX, Shen T
Journal of natural products 2020 Apr 24;83(4):1217-1228
Journal of natural products 2020 Apr 24;83(4):1217-1228
HIF-1β Positively Regulates NF-κB Activity via Direct Control of TRAF6.
D'Ignazio L, Shakir D, Batie M, Muller HA, Rocha S
International journal of molecular sciences 2020 Apr 24;21(8)
International journal of molecular sciences 2020 Apr 24;21(8)
Maternal curcumin supplementation ameliorates placental function and fetal growth in mice with intrauterine growth retardation†.
Qi L, Jiang J, Zhang J, Zhang L, Wang T
Biology of reproduction 2020 Apr 24;102(5):1090-1101
Biology of reproduction 2020 Apr 24;102(5):1090-1101
Pathogenic Variants in CEP85L Cause Sporadic and Familial Posterior Predominant Lissencephaly.
Tsai MH, Muir AM, Wang WJ, Kang YN, Yang KC, Chao NH, Wu MF, Chang YC, Porter BE, Jansen LA, Sebire G, Deconinck N, Fan WL, Su SC, Chung WH, Almanza Fuerte EP, Mehaffey MG, University of Washington Center for Mendelian Genomics., Ng CC, Chan CK, Lim KS, Leventer RJ, Lockhart PJ, Riney K, Damiano JA, Hildebrand MS, Mirzaa GM, Dobyns WB, Berkovic SF, Scheffer IE, Tsai JW, Mefford HC
Neuron 2020 Apr 22;106(2):237-245.e8
Neuron 2020 Apr 22;106(2):237-245.e8
Soluble epoxide hydrolase inhibitor protects against blood-brain barrier dysfunction in a mouse model of type 2 diabetes via the AMPK/HO-1 pathway.
Wu J, Zhao Y, Fan Z, Chen Q, Chen J, Sun Y, Jiang X, Xiao Q
Biochemical and biophysical research communications 2020 Apr 2;524(2):354-359
Biochemical and biophysical research communications 2020 Apr 2;524(2):354-359
AcMNPV PKIP is required for hyperexpression of very late genes and involved in the hyperphosphorylation of the viral basic protein P6.9.
Lai Q, Xu L, Wang Y, Luo W, Zhu L, Yuan M, Wu W, Yang K
Virus research 2020 Apr 2;279:197889
Virus research 2020 Apr 2;279:197889
Circadian clock gene Clock is involved in the pathogenesis of preeclampsia through hypoxia.
Li Y, Li J, Hou Y, Huang L, Bian Y, Song G, Qiao C
Life sciences 2020 Apr 15;247:117441
Life sciences 2020 Apr 15;247:117441
STIM2 knockdown protects against ischemia/reperfusion injury through reducing mitochondrial calcium overload and preserving mitochondrial function.
Tu CC, Wan BY, Zeng Y
Life sciences 2020 Apr 15;247:116560
Life sciences 2020 Apr 15;247:116560
The SCFβ-TrCP E3 Ubiquitin Ligase Regulates Immune Receptor Signaling by Targeting the Negative Regulatory Protein TIPE2.
Lou Y, Han M, Song Y, Zhong J, Zhang W, Chen YH, Wang H
Journal of immunology (Baltimore, Md. : 1950) 2020 Apr 15;204(8):2122-2132
Journal of immunology (Baltimore, Md. : 1950) 2020 Apr 15;204(8):2122-2132
Physicochemical characterization of polysaccharide from the leaf of Dendrobium officinale and effect on LPS induced damage in GES-1 cell.
Yang K, Lu T, Zhan L, Zhou C, Zhang N, Lei S, Wang Y, Yang J, Yan M, Lv G, Chen S
International journal of biological macromolecules 2020 Apr 15;149:320-330
International journal of biological macromolecules 2020 Apr 15;149:320-330
Trehalose attenuates renal ischemia-reperfusion injury by enhancing autophagy and inhibiting oxidative stress and inflammation.
Liu S, Yang Y, Gao H, Zhou N, Wang P, Zhang Y, Zhang A, Jia Z, Huang S
American journal of physiology. Renal physiology 2020 Apr 1;318(4):F994-F1005
American journal of physiology. Renal physiology 2020 Apr 1;318(4):F994-F1005
Localized injection of miRNA-21-enriched extracellular vesicles effectively restores cardiac function after myocardial infarction.
Song Y, Zhang C, Zhang J, Jiao Z, Dong N, Wang G, Wang Z, Wang L
Theranostics 2019;9(8):2346-2360
Theranostics 2019;9(8):2346-2360
HSF2 regulates aerobic glycolysis by suppression of FBP1 in hepatocellular carcinoma.
Yang LN, Ning ZY, Wang L, Yan X, Meng ZQ
American journal of cancer research 2019;9(8):1607-1621
American journal of cancer research 2019;9(8):1607-1621
Oncogenic MSH6-CXCR4-TGFB1 Feedback Loop: A Novel Therapeutic Target of Photothermal Therapy in Glioblastoma Multiforme.
Chen Y, Liu P, Sun P, Jiang J, Zhu Y, Dong T, Cui Y, Tian Y, An T, Zhang J, Li Z, Yang X
Theranostics 2019;9(5):1453-1473
Theranostics 2019;9(5):1453-1473
Targeting mitochondrial dynamics by regulating Mfn2 for therapeutic intervention in diabetic cardiomyopathy.
Hu L, Ding M, Tang D, Gao E, Li C, Wang K, Qi B, Qiu J, Zhao H, Chang P, Fu F, Li Y
Theranostics 2019;9(13):3687-3706
Theranostics 2019;9(13):3687-3706
Triptolide Induces Glioma Cell Autophagy and Apoptosis via Upregulating the ROS/JNK and Downregulating the Akt/mTOR Signaling Pathways.
Liu X, Zhao P, Wang X, Wang L, Zhu Y, Gao W
Frontiers in oncology 2019;9:387
Frontiers in oncology 2019;9:387
Identification of RE1-Silencing Transcription Factor as a Promoter of Metastasis in Pancreatic Cancer.
Jin H, Liu P, Kong L, Fei X, Gao Y, Wu T, Sun D, Tan X
Frontiers in oncology 2019;9:291
Frontiers in oncology 2019;9:291
Inhibition of oxidative stress by testosterone improves synaptic plasticity in senescence accelerated mice.
Wang L, Pei JH, Jia JX, Wang J, Song W, Fang X, Cai ZP, Huo DS, Wang H, Yang ZJ
Journal of toxicology and environmental health. Part A 2019;82(20):1061-1068
Journal of toxicology and environmental health. Part A 2019;82(20):1061-1068
Evidence for interaction of the NLRP3 inflammasome and Bruton's tyrosine kinase in tumor-associated macrophages: implications for myeloid cell production of interleukin-1beta.
Benner B, Scarberry L, Stiff A, Duggan MC, Good L, Lapurga G, Butchar JP, Tridandapani S, Carson WE
Oncoimmunology 2019;8(11):1659704
Oncoimmunology 2019;8(11):1659704
Bergenin Ameliorates MPTP-Induced Parkinson's Disease by Activating PI3K/Akt Signaling Pathway.
Ji Y, Wang D, Zhang B, Lu H
Journal of Alzheimer's disease : JAD 2019;72(3):823-833
Journal of Alzheimer's disease : JAD 2019;72(3):823-833
aFGF Promotes Neurite Growth by Regulating GSK3β-CRMP2 Signaling Pathway in Cortical Neurons Damaged by Amyloid-β.
Cao Q, Meng T, Man J, Peng D, Chen H, Xiang Q, Su Z, Zhang Q, Huang Y
Journal of Alzheimer's disease : JAD 2019;72(1):97-109
Journal of Alzheimer's disease : JAD 2019;72(1):97-109
Synergetic Inhibition of Human Colorectal Cancer Cells by Combining Polyyne-Enriched Fraction from Oplopanax elatus and Irinotecan.
Wang J, Shao L, Wang CZ, Zhou HH, Yuan CS, Huang WH
Nutrition and cancer 2019;71(3):472-482
Nutrition and cancer 2019;71(3):472-482
MiR-223-3p Alleviates Vascular Endothelial Injury by Targeting IL6ST in Kawasaki Disease.
Wang X, Ding YY, Chen Y, Xu QQ, Qian GH, Qian WG, Cao L, Zhou WP, Hou M, Lv HT
Frontiers in pediatrics 2019;7:288
Frontiers in pediatrics 2019;7:288
Loss of the Golgi Matrix Protein 130 Cause Aberrant IgA1 Glycosylation in IgA Nephropathy.
Wang C, Ye M, Zhao Q, Xia M, Liu D, He L, Chen G, Peng Y, Liu H
American journal of nephrology 2019;49(4):307-316
American journal of nephrology 2019;49(4):307-316
Chemo-Preventive Potential of Falcarindiol-Enriched Fraction from Oplopanax elatus on Colorectal Cancer Interfered by Human Gut Microbiota.
Wang J, Shao L, Rao T, Zhang W, Huang WH
The American journal of Chinese medicine 2019;47(6):1381-1404
The American journal of Chinese medicine 2019;47(6):1381-1404
Cinobufagin Promotes Cell Cycle Arrest and Apoptosis to Block Human Esophageal Squamous Cell Carcinoma Cells Growth via the p73 Signalling Pathway.
Deng X, Sheng J, Liu H, Wang N, Dai C, Wang Z, Zhang J, Zhao J, Dai E
Biological & pharmaceutical bulletin 2019;42(9):1500-1509
Biological & pharmaceutical bulletin 2019;42(9):1500-1509
Loss of Mitochondrial DNA by Gemcitabine Triggers Mitophagy and Cell Death.
Inamura A, Muraoka-Hirayama S, Sakurai K
Biological & pharmaceutical bulletin 2019;42(12):1977-1987
Biological & pharmaceutical bulletin 2019;42(12):1977-1987
RNA-seq analysis of PHD and VHL inhibitors reveals differences and similarities to the hypoxia response.
Frost J, Ciulli A, Rocha S
Wellcome open research 2019;4:17
Wellcome open research 2019;4:17
The Role of Nrf2 Signaling Pathway in Eucommia ulmoides Flavones Regulating Oxidative Stress in the Intestine of Piglets.
Xiao D, Yuan D, Tan B, Wang J, Liu Y, Tan B
Oxidative medicine and cellular longevity 2019;2019:9719618
Oxidative medicine and cellular longevity 2019;2019:9719618
Dexmedetomidine Attenuates Orthotopic Liver Transplantation-Induced Acute Gut Injury via α 2-Adrenergic Receptor-Dependent Suppression of Oxidative Stress.
Lv P, Chen T, Liu P, Zheng L, Tian J, Tan F, Chen J, Deng Y, Li J, Cai J, Chi X
Oxidative medicine and cellular longevity 2019;2019:9426368
Oxidative medicine and cellular longevity 2019;2019:9426368
Paneth Cell Ablation Aggravates Pancreatic and Intestinal Injuries in a Rat Model of Acute Necrotizing Pancreatitis after Normal and High-Fat Diet.
Guo Y, Huang C, Liu L, Fu X, Lu Y, Zheng J, Mei Q, Huang Z, Fan J, Lu L, Zeng Y
Mediators of inflammation 2019;2019:8474523
Mediators of inflammation 2019;2019:8474523
Palmitic Acid Induces MicroRNA-221 Expression to Decrease Glucose Uptake in HepG2 Cells via the PI3K/AKT/GLUT4 Pathway.
Huang F, Chen J, Wang J, Zhu P, Lin W
BioMed research international 2019;2019:8171989
BioMed research international 2019;2019:8171989
Tetrandrine-Induced Autophagy in MDA-MB-231 Triple-Negative Breast Cancer Cell through the Inhibition of PI3K/AKT/mTOR Signaling.
Guo Y, Pei X
Evidence-based complementary and alternative medicine : eCAM 2019;2019:7517431
Evidence-based complementary and alternative medicine : eCAM 2019;2019:7517431
N-n-Butyl Haloperidol Iodide Ameliorates Oxidative Stress in Mitochondria Induced by Hypoxia/Reoxygenation through the Mitochondrial c-Jun N-Terminal Kinase/Sab/Src/Reactive Oxygen Species Pathway in H9c2 Cells.
Chu Q, Zhang Y, Zhong S, Gao F, Chen Y, Wang B, Zhang Z, Cai W, Li W, Zheng F, Shi G
Oxidative medicine and cellular longevity 2019;2019:7417561
Oxidative medicine and cellular longevity 2019;2019:7417561
Oral Administration of Lactobacillus delbrueckii during the Suckling Phase Improves Antioxidant Activities and Immune Responses after the Weaning Event in a Piglet Model.
Li Y, Hou S, Peng W, Lin Q, Chen F, Yang L, Li F, Huang X
Oxidative medicine and cellular longevity 2019;2019:6919803
Oxidative medicine and cellular longevity 2019;2019:6919803
Minocycline Protects against Rotenone-Induced Neurotoxicity Correlating with Upregulation of Nurr1 in a Parkinson's Disease Rat Model.
Sun C, Wang Y, Mo M, Song C, Wang X, Chen S, Liu Y
BioMed research international 2019;2019:6843265
BioMed research international 2019;2019:6843265
Phosphocreatine Improves Cardiac Dysfunction by Normalizing Mitochondrial Respiratory Function through JAK2/STAT3 Signaling Pathway In Vivo and In Vitro.
Qaed E, Wang J, Almoiliqy M, Song Y, Liu W, Chu P, Alademi S, Alademi M, Li H, Alshwmi M, Al-Azab M, Ahsan A, Mahdi S, Han G, Niu M, Ali A, Shopit A, Wang H, Li X, Qaid A, Ma X, Li T, Peng J, Ma J, Zhang J, Tang Z
Oxidative medicine and cellular longevity 2019;2019:6521218
Oxidative medicine and cellular longevity 2019;2019:6521218
CD133 Is Associated with Increased Melanoma Cell Survival after Multikinase Inhibition.
Simbulan-Rosenthal CM, Gaur A, Zhou H, AbdusSamad M, Qin Q, Dougherty R, Aljehane L, Kuo LW, Vakili S, Karna K, Clark H, McCarron E, Rosenthal DS
Journal of oncology 2019;2019:6486173
Journal of oncology 2019;2019:6486173
CTGF Attenuates Tendon-Derived Stem/Progenitor Cell Aging.
Rui YF, Chen MH, Li YJ, Xiao LF, Geng P, Wang P, Xu ZY, Zhang XP, Dai GC
Stem cells international 2019;2019:6257537
Stem cells international 2019;2019:6257537
Reactive Oxygen Species Are Involved in the Development of Gastric Cancer and Gastric Cancer-Related Depression through ABL1-Mediated Inflammation Signaling Pathway.
Huang T, Zhou F, Yuan X, Yang T, Liang X, Wang Y, Tu H, Chang J, Nan K, Wei Y
Oxidative medicine and cellular longevity 2019;2019:5813985
Oxidative medicine and cellular longevity 2019;2019:5813985
Purple Sweet Potato Color Attenuates Kidney Damage by Blocking VEGFR2/ROS/NLRP3 Signaling in High-Fat Diet-Treated Mice.
Zheng GH, Shan Q, Mu JJ, Wang YJ, Zhang ZF, Fan SH, Hu B, Li MQ, Xie J, Chen P, Wu DM, Lu J, Zheng YL
Oxidative medicine and cellular longevity 2019;2019:5189819
Oxidative medicine and cellular longevity 2019;2019:5189819
Nicorandil Attenuates LPS-Induced Acute Lung Injury by Pulmonary Endothelial Cell Protection via NF-κB and MAPK Pathways.
He M, Shi W, Yu M, Li X, Xu J, Zhu J, Jin L, Xie W, Kong H
Oxidative medicine and cellular longevity 2019;2019:4957646
Oxidative medicine and cellular longevity 2019;2019:4957646
Shuangyu Tiaozhi Granule Attenuates Hypercholesterolemia through the Reduction of Cholesterol Synthesis in Rat Fed a High Cholesterol Diet.
Shi J, Li R, Liu Y, Lu H, Yu L, Zhang F
BioMed research international 2019;2019:4805926
BioMed research international 2019;2019:4805926
Prevention of Huntington's Disease-Like Behavioral Deficits in R6/1 Mouse by Tolfenamic Acid Is Associated with Decreases in Mutant Huntingtin and Oxidative Stress.
Liu P, Li Y, Yang W, Liu D, Ji X, Chi T, Guo Z, Li L, Zou L
Oxidative medicine and cellular longevity 2019;2019:4032428
Oxidative medicine and cellular longevity 2019;2019:4032428
Bu Shen Zhu Yun Decoction Improves Endometrial Receptivity via VEGFR-2-Mediated Angiogenesis.
Li L, Jiang H, Wei X, Geng D, He M, Du H
Evidence-based complementary and alternative medicine : eCAM 2019;2019:3949824
Evidence-based complementary and alternative medicine : eCAM 2019;2019:3949824
Yiqihuoxue Formula Activates Autophagy and Offers Renoprotection in a Rat Model of Adenine-Induced Kidney Disease.
Xia CH, Han XT, Zhang X, Zhu ZB, Guo J, Cui HL, Jiang HX, Huang WJ, Chen GZ, Liu YN, Liu WJ
Evidence-based complementary and alternative medicine : eCAM 2019;2019:3423981
Evidence-based complementary and alternative medicine : eCAM 2019;2019:3423981
Curcumin and Curcumol Inhibit NF-κB and TGF-β 1/Smads Signaling Pathways in CSE-Treated RAW246.7 Cells.
Li N, Liu TH, Yu JZ, Li CX, Liu Y, Wu YY, Yang ZS, Yuan JL
Evidence-based complementary and alternative medicine : eCAM 2019;2019:3035125
Evidence-based complementary and alternative medicine : eCAM 2019;2019:3035125
Astragalus Membranaceus Treatment Protects Raw264.7 Cells from Influenza Virus by Regulating G1 Phase and the TLR3-Mediated Signaling Pathway.
Liang Y, Zhang Q, Zhang L, Wang R, Xu X, Hu X
Evidence-based complementary and alternative medicine : eCAM 2019;2019:2971604
Evidence-based complementary and alternative medicine : eCAM 2019;2019:2971604
Salvianolic Acid A Protects the Kidney against Oxidative Stress by Activating the Akt/GSK-3β/Nrf2 Signaling Pathway and Inhibiting the NF-κB Signaling Pathway in 5/6 Nephrectomized Rats.
Zhang HF, Wang JH, Wang YL, Gao C, Gu YT, Huang J, Wang JH, Zhang Z
Oxidative medicine and cellular longevity 2019;2019:2853534
Oxidative medicine and cellular longevity 2019;2019:2853534
Stem Cells from Human Exfoliated Deciduous Teeth Ameliorate Diabetic Nephropathy In Vivo and In Vitro by Inhibiting Advanced Glycation End Product-Activated Epithelial-Mesenchymal Transition.
Rao N, Wang X, Xie J, Li J, Zhai Y, Li X, Fang T, Wang Y, Zhao Y, Ge L
Stem cells international 2019;2019:2751475
Stem cells international 2019;2019:2751475
Leukemia Inhibitory Factor Receptor Is Involved in Apoptosis in Rat Astrocytes Exposed to Oxygen-Glucose Deprivation.
Huo L, Fan Y, Wang H
BioMed research international 2019;2019:1613820
BioMed research international 2019;2019:1613820
Astragaloside IV Suppresses High Glucose-Induced NLRP3 Inflammasome Activation by Inhibiting TLR4/NF-κB and CaSR.
Leng B, Zhang Y, Liu X, Zhang Z, Liu Y, Wang H, Lu M
Mediators of inflammation 2019;2019:1082497
Mediators of inflammation 2019;2019:1082497
miR-100-3p inhibits cell proliferation and induces apoptosis in human gastric cancer through targeting to BMPR2.
Peng CW, Yue LX, Zhou YQ, Tang S, Kan C, Xia LM, Yang F, Wang SY
Cancer cell international 2019;19:354
Cancer cell international 2019;19:354
SSRP1 influences colorectal cancer cell growth and apoptosis via the AKT pathway.
Wang Q, Jia S, Jiao Y, Xu L, Wang D, Chen X, Hu X, Liang H, Wen N, Zhang S, Guo B, Zhang L
International journal of medical sciences 2019;16(12):1573-1582
International journal of medical sciences 2019;16(12):1573-1582
Fucoidan prevent murine autoimmune diabetes via suppression TLR4-signaling pathways, regulation DC/Treg induced immune tolerance and improving gut microecology.
Xue M, Liang H, Ji X, Liu Y, Ge Y, Hou L, Sun T
Nutrition & metabolism 2019;16:87
Nutrition & metabolism 2019;16:87
CXXC5 Mediates P. gingivalis-suppressed Cementoblast Functions Partially via MAPK Signaling Network.
Ma L, Wang X, Liu H, Jiang C, Liao H, Xu S, Guo Y, Cao Z
International journal of biological sciences 2019;15(8):1685-1695
International journal of biological sciences 2019;15(8):1685-1695
Fructose-1,6-bisphosphate prevents pulmonary fibrosis by regulating extracellular matrix deposition and inducing phenotype reversal of lung myofibroblasts.
Dias HB, de Oliveira JR, Donadio MVF, Kimura S
PloS one 2019;14(9):e0222202
PloS one 2019;14(9):e0222202
SPSB2 inhibits hepatitis C virus replication by targeting NS5A for ubiquitination and degradation.
Wang M, Wang Y, Liu Y, Wang H, Xin X, Li J, Hao Y, Han L, Yu F, Zheng C, Shen C
PloS one 2019;14(7):e0219989
PloS one 2019;14(7):e0219989
Resveratrol induced premature senescence and inhibited epithelial-mesenchymal transition of cancer cells via induction of tumor suppressor Rad9.
Chen KY, Chen CC, Chang YC, Chang MC
PloS one 2019;14(7):e0219317
PloS one 2019;14(7):e0219317
The Pseudogene PTTG3P Promotes Cell Migration and Invasion in Esophageal Squamous Cell Carcinoma.
Zhang Z, Shi Z
Open medicine (Warsaw, Poland) 2019;14:516-522
Open medicine (Warsaw, Poland) 2019;14:516-522
Synergism of cisplatin-oleanolic acid co-loaded calcium carbonate nanoparticles on hepatocellular carcinoma cells for enhanced apoptosis and reduced hepatotoxicity.
Khan MW, Zhao P, Khan A, Raza F, Raza SM, Sarfraz M, Chen Y, Li M, Yang T, Ma X, Xiang G
International journal of nanomedicine 2019;14:3753-3771
International journal of nanomedicine 2019;14:3753-3771
Treatment With Liraglutide Exerts Neuroprotection After Hypoxic-Ischemic Brain Injury in Neonatal Rats via the PI3K/AKT/GSK3β Pathway.
Zeng SS, Bai JJ, Jiang H, Zhu JJ, Fu CC, He MZ, Zhu JH, Chen SQ, Li PJ, Fu XQ, Lin ZL
Frontiers in cellular neuroscience 2019;13:585
Frontiers in cellular neuroscience 2019;13:585
Overexpression of CX3CR1 in Adipose-Derived Stem Cells Promotes Cell Migration and Functional Recovery After Experimental Intracerebral Hemorrhage.
Li G, Yu H, Liu N, Zhang P, Tang Y, Hu Y, Zhang Y, Pan C, Deng H, Wang J, Li Q, Tang Z
Frontiers in neuroscience 2019;13:462
Frontiers in neuroscience 2019;13:462
Arsenic sulfide induces miR-4665-3p to inhibit gastric cancer cell invasion and migration.
Zhang X, Tan Z, Kang T, Zhu C, Chen S
Drug design, development and therapy 2019;13:3037-3049
Drug design, development and therapy 2019;13:3037-3049
Hydrogen Sulfide Attenuates β2-Microglobulin-Induced Cognitive Dysfunction: Involving Recovery of Hippocampal Autophagic Flux.
Chen SM, Yi YL, Zeng D, Tang YY, Kang X, Zhang P, Zou W, Tang XQ
Frontiers in behavioral neuroscience 2019;13:244
Frontiers in behavioral neuroscience 2019;13:244
Necrostatin-1 Ameliorates Peripheral Nerve Injury-Induced Neuropathic Pain by Inhibiting the RIP1/RIP3 Pathway.
Liang YX, Wang NN, Zhang ZY, Juan ZD, Zhang C
Frontiers in cellular neuroscience 2019;13:211
Frontiers in cellular neuroscience 2019;13:211
The Neuroprotection of KIBRA in Promoting Neuron Survival and Against Amyloid β-Induced Apoptosis.
Song L, Tang S, Dong L, Han X, Cong L, Dong J, Han X, Zhang Q, Wang Y, Du Y
Frontiers in cellular neuroscience 2019;13:137
Frontiers in cellular neuroscience 2019;13:137
SUMOylation and deacetylation affect NF-κB p65 activity induced by high glucose in human lens epithelial cells.
Han X, Dong XX, Shi MY, Feng L, Wang XL, Zhang JS, Yan QC
International journal of ophthalmology 2019;12(9):1371-1379
International journal of ophthalmology 2019;12(9):1371-1379
Gatifloxacin inducing apoptosis of stromal fibroblasts through cross-talk between caspase-dependent extrinsic and intrinsic pathways.
Xu B, Sui YL, Fan TJ
International journal of ophthalmology 2019;12(10):1524-1530
International journal of ophthalmology 2019;12(10):1524-1530
Expression Of BMP7 In Ovarian Cancer And Biological Effect Of BMP7 Knockdown On Ovarian Cancer Cells.
Guan H, Li J, Sun R, Liu W, Feng M, Ma H, Li C
OncoTargets and therapy 2019;12:7897-7909
OncoTargets and therapy 2019;12:7897-7909
MicroRNA-765 sensitizes osteosarcoma cells to cisplatin via downregulating APE1 expression.
Liang W, Li C, Li M, Wang D, Zhong Z
OncoTargets and therapy 2019;12:7203-7214
OncoTargets and therapy 2019;12:7203-7214
LAPTM4B knockdown increases the radiosensitivity of EGFR-overexpressing radioresistant nasopharyngeal cancer cells by inhibiting autophagy.
Chu C, Niu X, Ou X, Hu C
OncoTargets and therapy 2019;12:5661-5677
OncoTargets and therapy 2019;12:5661-5677
β-elemene inhibits radiation and hypoxia-induced macrophages infiltration via Prx-1/NF-κB/HIF-1α signaling pathway.
Yu X, Li Z, Zhang Y, Xu M, Che Y, Tian X, Wang R, Zou K, Zou L
OncoTargets and therapy 2019;12:4203-4211
OncoTargets and therapy 2019;12:4203-4211
Exosomal Tenascin-c induces proliferation and invasion of pancreatic cancer cells by WNT signaling.
Qian S, Tan X, Liu X, Liu P, Wu Y
OncoTargets and therapy 2019;12:3197-3205
OncoTargets and therapy 2019;12:3197-3205
Multiple Functions of KBP in Neural Development Underlie Brain Anomalies in Goldberg-Shprintzen Syndrome.
Chang HY, Cheng HY, Tsao AN, Liu C, Tsai JW
Frontiers in molecular neuroscience 2019;12:265
Frontiers in molecular neuroscience 2019;12:265
Dichloroacetic acid upregulates apoptosis of ovarian cancer cells by regulating mitochondrial function.
Zhou L, Liu L, Chai W, Zhao T, Jin X, Guo X, Han L, Yuan C
OncoTargets and therapy 2019;12:1729-1739
OncoTargets and therapy 2019;12:1729-1739
miR-492 Promotes Cancer Progression by Targeting GJB4 and Is a Novel Biomarker for Bladder Cancer.
Wang K, Lü H, Qu H, Xie Q, Sun T, Gan O, Hu B
OncoTargets and therapy 2019;12:11453-11464
OncoTargets and therapy 2019;12:11453-11464
miR-509-5p Downregulation Is Associated With Male Infertility And Acts As A Suppressor In Testicular Germ Cell Tumor Cells Through Targeting MDM2.
Sun J, Niu L, Gao S, Yi X, Chen J
OncoTargets and therapy 2019;12:10515-10522
OncoTargets and therapy 2019;12:10515-10522
Escin protects against acetaminophen-induced liver injury in mice via attenuating inflammatory response and inhibiting ERK signaling pathway.
Lee HC, Yu HP, Liao CC, Chou AH, Liu FC
American journal of translational research 2019;11(8):5170-5182
American journal of translational research 2019;11(8):5170-5182
MiR-302a-5p suppresses cell proliferation and invasion in non-small cell lung carcinoma by targeting ITGA6.
Chen W, Zhuang X, Qi R, Qiao T
American journal of translational research 2019;11(7):4348-4357
American journal of translational research 2019;11(7):4348-4357
VASN promotes YAP/TAZ and EMT pathway in thyroid carcinogenesis in vitro.
Bhandari A, Guan Y, Xia E, Huang Q, Chen Y
American journal of translational research 2019;11(6):3589-3599
American journal of translational research 2019;11(6):3589-3599
Overexpression of CBX2 in breast cancer promotes tumor progression through the PI3K/AKT signaling pathway.
Zheng S, Lv P, Su J, Miao K, Xu H, Li M
American journal of translational research 2019;11(3):1668-1682
American journal of translational research 2019;11(3):1668-1682
BPTF cooperates with p50 NF-κB to promote COX-2 expression and tumor cell growth in lung cancer.
Dai M, Hu S, Liu CF, Jiang L, Yu W, Li ZL, Guo W, Tang R, Dong CY, Wu TH, Deng WG
American journal of translational research 2019;11(12):7398-7409
American journal of translational research 2019;11(12):7398-7409
Clinical roles of miR-136-5p and its target metadherin in thyroid carcinoma.
Gao RZ, Que Q, Lin P, Pang YY, Wu HY, Li XJ, Chen G, He Y, Yang H
American journal of translational research 2019;11(11):6754-6774
American journal of translational research 2019;11(11):6754-6774
Downregulation of angiopoietin-like protein 2 inhibits cementoblast differentiation partially by activating the ERK1/2 signaling pathway.
Jiang C, Liu H, Sun H, Wang X, Liao H, Ma L, Cao Z
American journal of translational research 2019;11(1):314-326
American journal of translational research 2019;11(1):314-326
ADAR1 may be involved in the proliferation of acute myeloid leukemia cells via regulation of the Wnt pathway.
Xiao H, Cheng Q, Wu X, Tang Y, Liu J, Li X
Cancer management and research 2019;11:8547-8555
Cancer management and research 2019;11:8547-8555
Overexpressed PKMYT1 promotes tumor progression and associates with poor survival in esophageal squamous cell carcinoma.
Zhang Q, Zhao X, Zhang C, Wang W, Li F, Liu D, Wu K, Zhu D, Liu S, Shen C, Yuan X, Zhang K, Yang Y, Zhang Y, Zhao S
Cancer management and research 2019;11:7813-7824
Cancer management and research 2019;11:7813-7824
HIF1α/miR-520a-3p/AKT1/mTOR Feedback Promotes The Proliferation And Glycolysis Of Gastric Cancer Cells.
Pan C, Liu Q, Wu X
Cancer management and research 2019;11:10145-10156
Cancer management and research 2019;11:10145-10156
STIP1 Regulates Proliferation and Migration of Lung Adenocarcinoma Through JAK2/STAT3 Signaling Pathway.
Guo X, Yan Z, Zhang G, Wang X, Pan Y, Huang M
Cancer management and research 2019;11:10061-10072
Cancer management and research 2019;11:10061-10072
Inhibition of RNA-Binding Protein Musashi-1 Suppresses Malignant Properties and Reverses Paclitaxel Resistance in Ovarian Carcinoma.
Chen H, Liu J, Wang H, Cheng Q, Zhou C, Chen X, Ye F
Journal of Cancer 2019;10(6):1580-1592
Journal of Cancer 2019;10(6):1580-1592
CLEC4M is associated with poor prognosis and promotes cisplatin resistance in NSCLC patients.
Tan LM, Li X, Qiu CF, Zhu T, Hu CP, Yin JY, Zhang W, Zhou HH, Liu ZQ
Journal of Cancer 2019;10(25):6374-6383
Journal of Cancer 2019;10(25):6374-6383
Methylation of SLFN11 promotes gastric cancer growth and increases gastric cancer cell resistance to cisplatin.
Peng Y, Wang L, Wu L, Zhang L, Nie G, Guo M
Journal of Cancer 2019;10(24):6124-6134
Journal of Cancer 2019;10(24):6124-6134
EP300 as an oncogene correlates with poor prognosis in esophageal squamous carcinoma.
Bi Y, Kong P, Zhang L, Cui H, Xu X, Chang F, Yan T, Li J, Cheng C, Song B, Niu X, Liu X, Liu X, Xu E, Hu X, Qian Y, Wang F, Li H, Ma Y, Yang J, Liu Y, Zhai Y, Wang Y, Zhang Y, Liu H, Liu J, Wang J, Cui Y, Cheng X
Journal of Cancer 2019;10(22):5413-5426
Journal of Cancer 2019;10(22):5413-5426
8-bromo-7-methoxychrysin targets NF-κB and FoxM1 to inhibit lung cancer stem cells induced by pro-inflammatory factors.
Yuan Q, Wen M, Xu C, Chen A, Qiu YB, Cao JG, Zhang JS, Song ZW
Journal of Cancer 2019;10(21):5244-5255
Journal of Cancer 2019;10(21):5244-5255
An NF90/long noncoding RNA-LET/miR-548k feedback amplification loop controls esophageal squamous cell carcinoma progression.
Lin J, Chen Z, Wu S, Huang W, Chen F, Huang Z
Journal of Cancer 2019;10(21):5139-5152
Journal of Cancer 2019;10(21):5139-5152
Verteporfin suppresses the proliferation, epithelial-mesenchymal transition and stemness of head and neck squamous carcinoma cells via inhibiting YAP1.
Liu K, Du S, Gao P, Zheng J
Journal of Cancer 2019;10(18):4196-4207
Journal of Cancer 2019;10(18):4196-4207
ITRAQ-Based Proteomics Analysis Reveals the Effect of Neoliensinine on KCl-Induced Vascular Smooth Muscle Contraction by Inhibiting Regulatory Light Chain Phosphorylation.
Yang GM, Yan K, Wang P, Zhang JL, Pan ZH, Pan Y
Frontiers in pharmacology 2019;10:979
Frontiers in pharmacology 2019;10:979
Discovery of N-(2-Aminophenyl)-4-(bis(2-chloroethyl)amino)Benzamide as a Potent Histone Deacetylase Inhibitor.
Zhang L, Li X, Chen Y, Wan M, Jiang Q, Zhang L, Chou CJ, Song W, Zhang L
Frontiers in pharmacology 2019;10:957
Frontiers in pharmacology 2019;10:957
A Novel Regulatory Circuit "C/EBPα/miR-20a-5p/TOB2" Regulates Adipogenesis and Lipogenesis.
Zhou J, Yang J, Wang X, Li M, Li F, Zhu E, Li X, Li X, Wang B
Frontiers in endocrinology 2019;10:894
Frontiers in endocrinology 2019;10:894
Effects of Exercise Training on the Autophagy-Related Muscular Proteins Expression in Ovariectomized Rats.
Zhong W, Shi X, Yuan H, Bu H, Wu L, Wang R
Frontiers in physiology 2019;10:735
Frontiers in physiology 2019;10:735
Irbesartan Ameliorates Lipid Deposition by Enhancing Autophagy via PKC/AMPK/ULK1 Axis in Free Fatty Acid Induced Hepatocytes.
He J, Ding J, Lai Q, Wang X, Li A, Liu S
Frontiers in physiology 2019;10:681
Frontiers in physiology 2019;10:681
Fish Autophagy Protein 5 Exerts Negative Regulation on Antiviral Immune Response Against Iridovirus and Nodavirus.
Li C, Liu J, Zhang X, Wei S, Huang X, Huang Y, Wei J, Qin Q
Frontiers in immunology 2019;10:517
Frontiers in immunology 2019;10:517
A Novel Postbiotic From Lactobacillus rhamnosus GG With a Beneficial Effect on Intestinal Barrier Function.
Gao J, Li Y, Wan Y, Hu T, Liu L, Yang S, Gong Z, Zeng Q, Wei Y, Yang W, Zeng Z, He X, Huang SH, Cao H
Frontiers in microbiology 2019;10:477
Frontiers in microbiology 2019;10:477
An improved Tet-on system in microRNA overexpression and CRISPR/Cas9-mediated gene editing.
Kang K, Huang L, Li Q, Liao X, Dang Q, Yang Y, Luo J, Zeng Y, Li L, Gou D
Journal of animal science and biotechnology 2019;10:43
Journal of animal science and biotechnology 2019;10:43
Identification of a Novel Bcl-2 Inhibitor by Ligand-Based Screening and Investigation of Its Anti-cancer Effect on Human Breast Cancer Cells.
Wen M, Deng ZK, Jiang SL, Guan YD, Wu HZ, Wang XL, Xiao SS, Zhang Y, Yang JM, Cao DS, Cheng Y
Frontiers in pharmacology 2019;10:391
Frontiers in pharmacology 2019;10:391
Prepartum body conditions affect insulin signaling pathways in postpartum adipose tissues in transition dairy cows.
Zhang F, Li D, Wu Q, Sun J, Guan W, Hou Y, Zhu Y, Wang J
Journal of animal science and biotechnology 2019;10:38
Journal of animal science and biotechnology 2019;10:38
Da-Bu-Yin-Wan and Qian-Zheng-San Ameliorate Mitochondrial Dynamics in the Parkinson's Disease Cell Model Induced by MPP.
Gai C, Feng WD, Qiang TY, Ma HJ, Chai Y, Zhang SJ, Guo ZY, Hu JH, Sun HM
Frontiers in pharmacology 2019;10:372
Frontiers in pharmacology 2019;10:372
The Involvement of Renin-Angiotensin System in Lipopolysaccharide-Induced Behavioral Changes, Neuroinflammation, and Disturbed Insulin Signaling.
Gong X, Hu H, Qiao Y, Xu P, Yang M, Dang R, Han W, Guo Y, Chen D, Jiang P
Frontiers in pharmacology 2019;10:318
Frontiers in pharmacology 2019;10:318
Epstein-Barr Virus Nuclear Antigen 1 Recruits Cyclophilin A to Facilitate the Replication of Viral DNA Genome.
Xin S, Du S, Liu L, Xie Y, Zuo L, Yang J, Hu J, Yue W, Zhang J, Cao P, Zhu F, Lu J
Frontiers in microbiology 2019;10:2879
Frontiers in microbiology 2019;10:2879
Dengue Virus Infection Activates Interleukin-1β to Induce Tissue Injury and Vascular Leakage.
Pan P, Zhang Q, Liu W, Wang W, Yu Z, Lao Z, Zhang W, Shen M, Wan P, Xiao F, Shereen MA, Zhang W, Tan Q, Liu Y, Liu X, Wu K, Liu Y, Li G, Wu J
Frontiers in microbiology 2019;10:2637
Frontiers in microbiology 2019;10:2637
Hypertensive Rats Treated Chronically With Nω-Nitro-L-Arginine Methyl Ester (L-NAME) Induced Disorder of Hepatic Fatty Acid Metabolism and Intestinal Pathophysiology.
Li B, He X, Lei SS, Zhou FC, Zhang NY, Chen YH, Wang YZ, Su J, Yu JJ, Li LZ, Zheng X, Luo R, Kołodyńska D, Xiong S, Lv GY, Chen SH
Frontiers in pharmacology 2019;10:1677
Frontiers in pharmacology 2019;10:1677
Cathelicidin-WA Facilitated Intestinal Fatty Acid Absorption Through Enhancing PPAR-γ Dependent Barrier Function.
Zong X, Cao X, Wang H, Xiao X, Wang Y, Lu Z
Frontiers in immunology 2019;10:1674
Frontiers in immunology 2019;10:1674
The Capsid Protein VP1 of Coxsackievirus B Induces Cell Cycle Arrest by Up-Regulating Heat Shock Protein 70.
Wang Y, Zhao S, Chen Y, Wang T, Dong C, Wo X, Zhang J, Dong Y, Xu W, Feng X, Qu C, Wang Y, Zhong Z, Zhao W
Frontiers in microbiology 2019;10:1633
Frontiers in microbiology 2019;10:1633
LncRNA LUCRC Regulates Colorectal Cancer Cell Growth and Tumorigenesis by Targeting Endoplasmic Reticulum Stress Response.
Tang GH, Chen X, Ding JC, Du J, Lin XT, Xia L, Lian JB, Ye F, He XS, Liu W
Frontiers in genetics 2019;10:1409
Frontiers in genetics 2019;10:1409
Ghrelin Attenuates Neuroinflammation and Demyelination in Experimental Autoimmune Encephalomyelitis Involving NLRP3 Inflammasome Signaling Pathway and Pyroptosis.
Liu F, Li Z, He X, Yu H, Feng J
Frontiers in pharmacology 2019;10:1320
Frontiers in pharmacology 2019;10:1320
An Improved Enzyme-Linked Focus Formation Assay Revealed Baloxavir Acid as a Potential Antiviral Therapeutic Against Hantavirus Infection.
Ye C, Wang D, Liu H, Ma H, Dong Y, Yao M, Wang Y, Zhang H, Zhang L, Cheng L, Xu Z, Lei Y, Zhang F, Ye W
Frontiers in pharmacology 2019;10:1203
Frontiers in pharmacology 2019;10:1203
LPS Induces Preeclampsia-Like Phenotype in Rats and HTR8/SVneo Cells Dysfunction Through TLR4/p38 MAPK Pathway.
Fan M, Li X, Gao X, Dong L, Xin G, Chen L, Qiu J, Xu Y
Frontiers in physiology 2019;10:1030
Frontiers in physiology 2019;10:1030
Sorghum Phenolics Inhibits Inflammasomes in Lipopolysaccharide (LPS)-Primed and Adenosine Triphosphate (ATP)-Activated Macrophages.
Dia VP, Bradwell J, Pangloli P
Plant foods for human nutrition (Dordrecht, Netherlands) 2019 Sep;74(3):307-315
Plant foods for human nutrition (Dordrecht, Netherlands) 2019 Sep;74(3):307-315
Functional evidence for a de novo mutation in WDR45 leading to BPAN in a Chinese girl.
Xiong Q, Li W, Li P, Zhao Z, Wu C, Xiao H
Molecular genetics & genomic medicine 2019 Sep;7(9):e858
Molecular genetics & genomic medicine 2019 Sep;7(9):e858
Aerobic Exercise Improves Synaptic-Related Proteins of Diabetic Rats by Inhibiting FOXO1/NF-κB/NLRP3 Inflammatory Signaling Pathway and Ameliorating PI3K/Akt Insulin Signaling Pathway.
Wang Q, Hu J, Liu Y, Li J, Liu B, Li M, Lou S
Journal of molecular neuroscience : MN 2019 Sep;69(1):28-38
Journal of molecular neuroscience : MN 2019 Sep;69(1):28-38
Comparison of the Effects of Green and Black Tea Extracts on Na+ /K+ -ATPase Activity in Intestine of Type 1 and Type 2 Diabetic Mice.
Qu F, Liu S, He C, Zhou J, Zhang S, Ai Z, Chen Y, Yu Z, Ni D
Molecular nutrition & food research 2019 Sep;63(17):e1801039
Molecular nutrition & food research 2019 Sep;63(17):e1801039
Mechanosensitive ion channel Piezo1 promotes prostate cancer development through the activation of the Akt/mTOR pathway and acceleration of cell cycle.
Han Y, Liu C, Zhang D, Men H, Huo L, Geng Q, Wang S, Gao Y, Zhang W, Zhang Y, Jia Z
International journal of oncology 2019 Sep;55(3):629-644
International journal of oncology 2019 Sep;55(3):629-644
MicroRNA-191 promotes hepatocellular carcinoma cell proliferation by has_circ_0000204/miR-191/KLF6 axis.
Tian F, Yu C, Wu M, Wu X, Wan L, Zhu X
Cell proliferation 2019 Sep;52(5):e12635
Cell proliferation 2019 Sep;52(5):e12635
Cardiac troponin I autoantibody induces myocardial dysfunction by PTEN signaling activation.
Wu Y, Qin YH, Liu Y, Zhu L, Zhao XX, Liu YY, Luo SW, Tang GS, Shen Q
EBioMedicine 2019 Sep;47:329-340
EBioMedicine 2019 Sep;47:329-340
DEPDC1 drives hepatocellular carcinoma cell proliferation, invasion and angiogenesis by regulating the CCL20/CCR6 signaling pathway.
Guo W, Li H, Liu H, Ma X, Yang S, Wang Z
Oncology reports 2019 Sep;42(3):1075-1089
Oncology reports 2019 Sep;42(3):1075-1089
Eukaryotic elongation factor-2 kinase regulates the cross-talk between autophagy and pyroptosis in doxorubicin-treated human melanoma cells in vitro.
Yu P, Wang HY, Tian M, Li AX, Chen XS, Wang XL, Zhang Y, Cheng Y
Acta pharmacologica Sinica 2019 Sep;40(9):1237-1244
Acta pharmacologica Sinica 2019 Sep;40(9):1237-1244
The Functional Polymorphism R129W in the BVES Gene Is Associated with Sporadic Tetralogy of Fallot in the Han Chinese Population.
Shi Y, Li Y, Wang Y, Zhuang J, Wang H, Hu M, Mo X, Yue S, Chen Y, Fan X, Chen J, Cai W, Zhu X, Wan Y, Zhong Y, Ye X, Li F, Zhou Z, Dai G, Luo R, Ocorr K, Jiang Z, Li X, Zhu P, Wu X, Yuan W
Genetic testing and molecular biomarkers 2019 Sep;23(9):601-609
Genetic testing and molecular biomarkers 2019 Sep;23(9):601-609
Ursolic acid suppresses the invasive potential of colorectal cancer cells by regulating the TGF-β1/ZEB1/miR-200c signaling pathway.
Zhang L, Cai QY, Liu J, Peng J, Chen YQ, Sferra TJ, Lin JM
Oncology letters 2019 Sep;18(3):3274-3282
Oncology letters 2019 Sep;18(3):3274-3282
2',4'-Dihydroxy-6'-methoxy-3',5'-dimethylchalcone induced apoptosis and G1 cell cycle arrest through PI3K/AKT pathway in BEL-7402/5-FU cells.
Ji X, Wei X, Qian J, Mo X, Kai G, An F, Lu Y
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2019 Sep;131:110533
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2019 Sep;131:110533
HOXA11-AS regulates JAK-STAT pathway by miR-15a-3p/STAT3 axis to promote the growth and metastasis in liver cancer.
Wang S, Zhang S, He Y, Huang X, Hui Y, Tang Y
Journal of cellular biochemistry 2019 Sep;120(9):15941-15951
Journal of cellular biochemistry 2019 Sep;120(9):15941-15951
SARI attenuates colon inflammation by promoting STAT1 degradation in intestinal epithelial cells.
Dai L, Liu Y, Cheng L, Wang H, Lin Y, Shi G, Dong Z, Li J, Fan P, Wang Q, Su X, Zhang S, Yang Y, Hu X, Huang W, Zhou Z, Yu D, Probert C, Wei Y, Deng H
Mucosal immunology 2019 Sep;12(5):1130-1140
Mucosal immunology 2019 Sep;12(5):1130-1140
Induction of Nrf2 pathway by Dendrobium nobile Lindl. alkaloids protects against carbon tetrachloride induced acute liver injury.
Li S, Zhou J, Xu S, Li J, Liu J, Lu Y, Shi J, Zhou S, Wu Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Sep;117:109073
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Sep;117:109073
A hidden human proteome encoded by 'non-coding' genes.
Lu S, Zhang J, Lian X, Sun L, Meng K, Chen Y, Sun Z, Yin X, Li Y, Zhao J, Wang T, Zhang G, He QY
Nucleic acids research 2019 Sep 5;47(15):8111-8125
Nucleic acids research 2019 Sep 5;47(15):8111-8125
LINC01123, a c-Myc-activated long non-coding RNA, promotes proliferation and aerobic glycolysis of non-small cell lung cancer through miR-199a-5p/c-Myc axis.
Hua Q, Jin M, Mi B, Xu F, Li T, Zhao L, Liu J, Huang G
Journal of hematology & oncology 2019 Sep 5;12(1):91
Journal of hematology & oncology 2019 Sep 5;12(1):91
CDK5-dependent phosphorylation and nuclear translocation of TRIM59 promotes macroH2A1 ubiquitination and tumorigenicity.
Sang Y, Li Y, Zhang Y, Alvarez AA, Yu B, Zhang W, Hu B, Cheng SY, Feng H
Nature communications 2019 Sep 5;10(1):4013
Nature communications 2019 Sep 5;10(1):4013
Applying vibration in early postmenopausal osteoporosis promotes osteogenic differentiation of bone marrow-derived mesenchymal stem cells and suppresses postmenopausal osteoporosis progression.
Li H, Wu W, He X, Cao C, Yu X, Zeng Y, Li L
Bioscience reports 2019 Sep 30;39(9)
Bioscience reports 2019 Sep 30;39(9)
Fine particulate matters induce apoptosis via the ATM/P53/CDK2 and mitochondria apoptosis pathway triggered by oxidative stress in rat and GC-2spd cell.
Liu J, Zhang J, Ren L, Wei J, Zhu Y, Duan J, Jing L, Sun Z, Zhou X
Ecotoxicology and environmental safety 2019 Sep 30;180:280-287
Ecotoxicology and environmental safety 2019 Sep 30;180:280-287
NRF2-dependent gene expression promotes ciliogenesis and Hedgehog signaling.
Martin-Hurtado A, Martin-Morales R, Robledinos-Antón N, Blanco R, Palacios-Blanco I, Lastres-Becker I, Cuadrado A, Garcia-Gonzalo FR
Scientific reports 2019 Sep 25;9(1):13896
Scientific reports 2019 Sep 25;9(1):13896
MiR-143-3p directly targets GLUT9 to reduce uric acid reabsorption and inflammatory response of renal tubular epithelial cells.
Zhou Z, Dong Y, Zhou H, Liu J, Zhao W
Biochemical and biophysical research communications 2019 Sep 24;517(3):413-420
Biochemical and biophysical research communications 2019 Sep 24;517(3):413-420
Kinsenoside ameliorates intervertebral disc degeneration through the activation of AKT-ERK1/2-Nrf2 signaling pathway.
Wang Y, Zuo R, Wang Z, Luo L, Wu J, Zhang C, Liu M, Shi C, Zhou Y
Aging 2019 Sep 23;11(18):7961-7977
Aging 2019 Sep 23;11(18):7961-7977
Accelerated Metabolite Levels of Aerobic Glycolysis and the Pentose Phosphate Pathway Are Required for Efficient Replication of Infectious Spleen and Kidney Necrosis Virus in Chinese Perch Brain Cells.
Guo X, Wu S, Li N, Lin Q, Liu L, Liang H, Niu Y, Huang Z, Fu X
Biomolecules 2019 Sep 2;9(9)
Biomolecules 2019 Sep 2;9(9)
Long non-coding RNA, HOTAIRM1, promotes glioma malignancy by forming a ceRNA network.
Liang Q, Li X, Guan G, Xu X, Chen C, Cheng P, Cheng W, Wu A
Aging 2019 Sep 2;11(17):6805-6838
Aging 2019 Sep 2;11(17):6805-6838
Maltol (3-Hydroxy-2-methyl-4-pyrone) Slows d-Galactose-Induced Brain Aging Process by Damping the Nrf2/HO-1-Mediated Oxidative Stress in Mice.
Sha JY, Zhou YD, Yang JY, Leng J, Li JH, Hu JN, Liu W, Jiang S, Wang YP, Chen C, Li W
Journal of agricultural and food chemistry 2019 Sep 18;67(37):10342-10351
Journal of agricultural and food chemistry 2019 Sep 18;67(37):10342-10351
Exosomes derived from cardiac progenitor cells attenuate CVB3-induced apoptosis via abrogating the proliferation of CVB3 and modulating the mTOR signaling pathways.
Li X, Yang Z, Nie W, Jiang J, Li S, Li Z, Tian L, Ma X
Cell death & disease 2019 Sep 18;10(10):691
Cell death & disease 2019 Sep 18;10(10):691
Bisdemethoxycurcumin Protection of Cardiomyocyte Mainly Depends on Nrf2/HO-1 Activation Mediated by the PI3K/AKT Pathway.
Li X, Huo C, Xiao Y, Xu R, Liu Y, Jia X, Wang X
Chemical research in toxicology 2019 Sep 16;32(9):1871-1879
Chemical research in toxicology 2019 Sep 16;32(9):1871-1879
Regulatory effect of a Chinese herbal medicine formula on non-alcoholic fatty liver disease.
Yang JM, Sun Y, Wang M, Zhang XL, Zhang SJ, Gao YS, Chen L, Wu MY, Zhou L, Zhou YM, Wang Y, Zheng FJ, Li YH
World journal of gastroenterology 2019 Sep 14;25(34):5105-5119
World journal of gastroenterology 2019 Sep 14;25(34):5105-5119
Artocarmitin B enhances intracellular antioxidant capacity via activation of Nrf2 signaling pathway in human lung epithelial cells.
Wu XY, Chen XM, Zhou MX, Hu HX, Zhang JZ, Wang XN, Ren DM, Lou HX, Shen T
Chemico-biological interactions 2019 Sep 1;310:108741
Chemico-biological interactions 2019 Sep 1;310:108741
Tetrandrine and cepharanthine induce apoptosis through caspase cascade regulation, cell cycle arrest, MAPK activation and PI3K/Akt/mTOR signal modification in glucocorticoid resistant human leukemia Jurkat T cells.
Xu W, Wang X, Tu Y, Masaki H, Tanaka S, Onda K, Sugiyama K, Yamada H, Hirano T
Chemico-biological interactions 2019 Sep 1;310:108726
Chemico-biological interactions 2019 Sep 1;310:108726
Astragaloside IV protects against hyperglycemia-induced vascular endothelial dysfunction by inhibiting oxidative stress and Calpain-1 activation.
Nie Q, Zhu L, Zhang L, Leng B, Wang H
Life sciences 2019 Sep 1;232:116662
Life sciences 2019 Sep 1;232:116662
The protective effects of Ghrelin/GHSR on hippocampal neurogenesis in CUMS mice.
Huang HJ, Chen XR, Han QQ, Wang J, Pilot A, Yu R, Liu Q, Li B, Wu GC, Wang YQ, Yu J
Neuropharmacology 2019 Sep 1;155:31-43
Neuropharmacology 2019 Sep 1;155:31-43
Grouper Atg12 negatively regulates the antiviral immune response against Singapore grouper iridovirus (SGIV) infection.
Li C, Yu Y, Zhang X, Wei J, Qin Q
Fish & shellfish immunology 2019 Oct;93:702-710
Fish & shellfish immunology 2019 Oct;93:702-710
MicroRNA-182-3p negatively regulates cytokines expression by targeting TLR5M in orange-spotted grouper, Epinephelus coioides.
He L, Zhao M, Yu X, Zhao Y, Fu L, Qiao X, Lin H, Zhang Y, Li G, Li S, Lu D
Fish & shellfish immunology 2019 Oct;93:589-596
Fish & shellfish immunology 2019 Oct;93:589-596
Naringin mitigates myocardial strain and the inflammatory response in sepsis-induced myocardial dysfunction through regulation of PI3K/AKT/NF-κB pathway.
Sun LJ, Qiao W, Xiao YJ, Cui L, Wang X, Ren WD
International immunopharmacology 2019 Oct;75:105782
International immunopharmacology 2019 Oct;75:105782
Rhein inhibits ATP-triggered inflammatory responses in rheumatoid rat fibroblast-like synoviocytes.
Hu F, Zhu D, Pei W, Lee I, Zhang X, Pan L, Xu J
International immunopharmacology 2019 Oct;75:105780
International immunopharmacology 2019 Oct;75:105780
SIRT1-regulated HMGB1 release is partially involved in TLR4 signal transduction: A possible anti-neuroinflammatory mechanism of resveratrol in neonatal hypoxic-ischemic brain injury.
Le K, Chibaatar Daliv E, Wu S, Qian F, Ali AI, Yu D, Guo Y
International immunopharmacology 2019 Oct;75:105779
International immunopharmacology 2019 Oct;75:105779
USP22 Deubiquitinates CD274 to Suppress Anticancer Immunity.
Huang X, Zhang Q, Lou Y, Wang J, Zhao X, Wang L, Zhang X, Li S, Zhao Y, Chen Q, Liang T, Bai X
Cancer immunology research 2019 Oct;7(10):1580-1590
Cancer immunology research 2019 Oct;7(10):1580-1590
Overexpression of Limb-Bud and Heart (LBH) promotes angiogenesis in human glioma via VEGFA-mediated ERK signalling under hypoxia.
Jiang Y, Zhou J, Zou D, Hou D, Zhang H, Zhao J, Li L, Hu J, Zhang Y, Jing Z
EBioMedicine 2019 Oct;48:36-48
EBioMedicine 2019 Oct;48:36-48
MiR-26a promotes fracture healing of nonunion rats possibly by targeting SOSTDC1 and further activating Wnt/β-catenin signaling pathway.
Sun L, Li Z, Xue H, Ma T, Ren C, Li M, Lu Y, Sun H, Zhang K
Molecular and cellular biochemistry 2019 Oct;460(1-2):165-173
Molecular and cellular biochemistry 2019 Oct;460(1-2):165-173
Ginsenoside compound K ameliorates Alzheimer's disease in HT22 cells by adjusting energy metabolism.
Chen X, Li H, Yang Q, Lan X, Wang J, Cao Z, Shi X, Li J, Kan M, Qu X, Li N
Molecular biology reports 2019 Oct;46(5):5323-5332
Molecular biology reports 2019 Oct;46(5):5323-5332
Dioscin attenuates Bleomycin-Induced acute lung injury via inhibiting the inflammatory response in mice.
Wu ZL, Wang J
Experimental lung research 2019 Oct;45(8):236-244
Experimental lung research 2019 Oct;45(8):236-244
Propentofylline reduces mechanical allodynia and induces mitogen-activated protein kinase phosphatase-1: An experimental study in a rat model of acute incisional pain.
Yang Y, Shi Y, Jia J, Wang S, Chang H, Li M, Jin X, Wang J
Neurological research 2019 Oct;41(10):900-908
Neurological research 2019 Oct;41(10):900-908
PM2.5 upregulates rat mesenteric arteries 5-HT2A receptor via inflammatory-mediated mitogen-activated protein kinases signaling pathway.
Wang R, Cao L, Shen ZX, Cao YX, Yu J
Environmental toxicology 2019 Oct;34(10):1094-1104
Environmental toxicology 2019 Oct;34(10):1094-1104
MYCT1 represses apoptosis of laryngeal cancerous cells through the MAX/miR-181a/NPM1 pathway.
Wang HT, Tong X, Zhang ZX, Sun YY, Yan W, Xu ZM, Fu WN
The FEBS journal 2019 Oct;286(19):3892-3908
The FEBS journal 2019 Oct;286(19):3892-3908
LncRNA ADPGK-AS1 regulated cell proliferation, invasion, migration and apoptosis via targeting miR-542-3p in osteosarcoma.
Luo XF, Wu XJ, Wei X, Wang AG, Wang SH, Wang JL
European review for medical and pharmacological sciences 2019 Oct;23(20):8751-8760
European review for medical and pharmacological sciences 2019 Oct;23(20):8751-8760
Berberine attenuates XRCC1-mediated base excision repair and sensitizes breast cancer cells to the chemotherapeutic drugs.
Gao X, Wang J, Li M, Wang J, Lv J, Zhang L, Sun C, Ji J, Yang W, Zhao Z, Mao W
Journal of cellular and molecular medicine 2019 Oct;23(10):6797-6804
Journal of cellular and molecular medicine 2019 Oct;23(10):6797-6804
Glycine cleavage system determines the fate of pluripotent stem cells via the regulation of senescence and epigenetic modifications.
Tian S, Feng J, Cao Y, Shen S, Cai Y, Yang D, Yan R, Wang L, Zhang H, Zhong X, Gao P
Life science alliance 2019 Oct;2(5)
Life science alliance 2019 Oct;2(5)
Cleavage and polyadenylation specific factor 4 promotes colon cancer progression by transcriptionally activating hTERT.
Yang Q, Fan W, Zheng Z, Lin S, Liu C, Wang R, Li W, Zuo Y, Sun Y, Hu S, Chen M, Guo P, Pan J, Tian C, Zhu T, Diao C, Hao J, Yu W, Li L, Li Y, Guo W, Deng W, Wu X
Biochimica et biophysica acta. Molecular cell research 2019 Oct;1866(10):1533-1543
Biochimica et biophysica acta. Molecular cell research 2019 Oct;1866(10):1533-1543
Apigenin reduces the excessive accumulation of lipids induced by palmitic acid via the AMPK signaling pathway in HepG2 cells.
Lu J, Meng Z, Cheng B, Liu M, Tao S, Guan S
Experimental and therapeutic medicine 2019 Oct;18(4):2965-2971
Experimental and therapeutic medicine 2019 Oct;18(4):2965-2971
The development of a cell-based model for the assessment of carcinogenic potential upon long-term PM2.5 exposure.
Chen S, Li D, Zhang H, Yu D, Chen R, Zhang B, Tan Y, Niu Y, Duan H, Mai B, Chen S, Yu J, Luan T, Chen L, Xing X, Li Q, Xiao Y, Dong G, Niu Y, Aschner M, Zhang R, Zheng Y, Chen W
Environment international 2019 Oct;131:104943
Environment international 2019 Oct;131:104943
Inhibition of myeloid differentiation 1 specifically in colon with antisense oligonucleotide exacerbates dextran sodium sulfate-induced colitis.
Chen X, Pan H, Li J, Zhang G, Cheng S, Zuo N, Zhao Q, Peng Z
Journal of cellular biochemistry 2019 Oct;120(10):16888-16899
Journal of cellular biochemistry 2019 Oct;120(10):16888-16899
RNA sequencing analysis of the CAL-27 cell response to over-expressed ZNF750 gene revealed an extensive regulation on cell cycle.
Liu X, Yang Y, Xu C, Yang H, Chen S, Chen H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109377
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109377
Limonin enhances the radiosensitivity of nasopharyngeal carcinoma cells via attenuating Stat3-induced cell stemness.
Gao L, Sang JZ, Cao H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109366
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109366
SIRT1 activation attenuates cardiac fibrosis by endothelial-to-mesenchymal transition.
Liu ZH, Zhang Y, Wang X, Fan XF, Zhang Y, Li X, Gong YS, Han LP
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109227
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109227
Inhibition of high mobility group box 1 (HMGB1) attenuates podocyte apoptosis and epithelial-mesenchymal transition by regulating autophagy flux.
Jin J, Gong J, Zhao L, Zhang H, He Q, Jiang X
Journal of diabetes 2019 Oct;11(10):826-836
Journal of diabetes 2019 Oct;11(10):826-836
MiR-16a Regulates Milk Fat Metabolism by Targeting Large Tumor Suppressor Kinase 1 (LATS1) in Bovine Mammary Epithelial Cells.
Chen Z, Chu S, Wang X, Sun Y, Xu T, Mao Y, Loor JJ, Yang Z
Journal of agricultural and food chemistry 2019 Oct 9;67(40):11167-11178
Journal of agricultural and food chemistry 2019 Oct 9;67(40):11167-11178
Viral N6-methyladenosine upregulates replication and pathogenesis of human respiratory syncytial virus.
Xue M, Zhao BS, Zhang Z, Lu M, Harder O, Chen P, Lu Z, Li A, Ma Y, Xu Y, Liang X, Zhou J, Niewiesk S, Peeples ME, He C, Li J
Nature communications 2019 Oct 9;10(1):4595
Nature communications 2019 Oct 9;10(1):4595
CircWHSC1 promotes ovarian cancer progression by regulating MUC1 and hTERT through sponging miR-145 and miR-1182.
Zong ZH, Du YP, Guan X, Chen S, Zhao Y
Journal of experimental & clinical cancer research : CR 2019 Oct 30;38(1):437
Journal of experimental & clinical cancer research : CR 2019 Oct 30;38(1):437
Oxidative stress-induced cellular senescence desensitizes cell growth and migration of vascular smooth muscle cells through down-regulation of platelet-derived growth factor receptor-beta.
Pan CH, Chen CJ, Shih CM, Wang MF, Wang JY, Wu CH
Aging 2019 Oct 3;11(19):8085-8102
Aging 2019 Oct 3;11(19):8085-8102
Tumor vasculature remolding by thalidomide increases delivery and efficacy of cisplatin.
Shen Y, Li S, Wang X, Wang M, Tian Q, Yang J, Wang J, Wang B, Liu P, Yang J
Journal of experimental & clinical cancer research : CR 2019 Oct 28;38(1):427
Journal of experimental & clinical cancer research : CR 2019 Oct 28;38(1):427
Knockout of neutrophil elastase protects against western diet induced nonalcoholic steatohepatitis in mice by regulating hepatic ceramides metabolism.
Chen J, Liang B, Bian D, Luo Y, Yang J, Li Z, Zhuang Z, Zang S, Shi J
Biochemical and biophysical research communications 2019 Oct 22;518(4):691-697
Biochemical and biophysical research communications 2019 Oct 22;518(4):691-697
SPOP suppresses pancreatic cancer progression by promoting the degradation of NANOG.
Tan P, Xu Y, Du Y, Wu L, Guo B, Huang S, Zhu J, Li B, Lin F, Yao L
Cell death & disease 2019 Oct 17;10(11):794
Cell death & disease 2019 Oct 17;10(11):794
Circ-Spidr enhances axon regeneration after peripheral nerve injury.
Mao S, Huang T, Chen Y, Shen L, Zhou S, Zhang S, Yu B
Cell death & disease 2019 Oct 17;10(11):787
Cell death & disease 2019 Oct 17;10(11):787
γ-Oryzanol alleviates acetaminophen-induced liver injury: roles of modulating AMPK/GSK3β/Nrf2 and NF-κB signaling pathways.
Shu G, Qiu Y, Hao J, Fu Q, Deng X
Food & function 2019 Oct 16;10(10):6858-6872
Food & function 2019 Oct 16;10(10):6858-6872
Six1 is negatively correlated with poor prognosis and reduces 5-fluorouracil sensitivity via attenuating the stemness of hepatocellular carcinoma cells.
Chen K, Wei H, Pan J, Chen Z, Pan D, Gao T, Huang J, Huang M, Ou M, Zhong W
European journal of pharmacology 2019 Oct 15;861:172599
European journal of pharmacology 2019 Oct 15;861:172599
Angiotensin II deteriorates advanced atherosclerosis by promoting MerTK cleavage and impairing efferocytosis through the AT1R/ROS/p38 MAPK/ADAM17 pathway.
Zhang Y, Wang Y, Zhou D, Zhang LS, Deng FX, Shu S, Wang LJ, Wu Y, Guo N, Zhou J, Yuan ZY
American journal of physiology. Cell physiology 2019 Oct 1;317(4):C776-C787
American journal of physiology. Cell physiology 2019 Oct 1;317(4):C776-C787
Melatonin Receptor Mel1b- and Mel1c-mediated Green Light Induced the Secretion of Growth Hormone in Anterior Pituitary of Chicks.
Yue L, Qin X, Liu X, Wang Z, Dong Y, Chen Y, Cao J
Photochemistry and photobiology 2019 Nov;95(6):1387-1394
Photochemistry and photobiology 2019 Nov;95(6):1387-1394
A novel RING finger protein CqRNF152-like with self-ubiquitination activity inhibits white spot syndrome virus infection in a crustacean Cherax quadricarinatus.
Zheng SC, Chang XJ, Li WD, Wang H, Guo LM, Wang KJ, Liu HP
Fish & shellfish immunology 2019 Nov;94:934-943
Fish & shellfish immunology 2019 Nov;94:934-943
Zinc alleviates arsenism in common carp: Varied change profiles of cytokines and tight junction proteins among two intestinal segments.
Zhao H, Wang Y, Yang X, Fei D, Mu M, Guo M, Yu H, Xing M
Fish & shellfish immunology 2019 Nov;94:761-768
Fish & shellfish immunology 2019 Nov;94:761-768
Molecular cloning, expression and functional analysis of Atg16L1 from orange-spotted grouper (Epinephelus coioides).
Li C, Wang L, Zhang X, Wei J, Qin Q
Fish & shellfish immunology 2019 Nov;94:113-121
Fish & shellfish immunology 2019 Nov;94:113-121
Screening candidate microR-15a- IRAK2 regulatory pairs for predicting the response to Staphylococcus aureus-induced mastitis in dairy cows.
Chen Z, Zhou J, Wang X, Zhang Y, Lu X, Fan Y, Mao Y, Loor JJ, Yang Z
The Journal of dairy research 2019 Nov;86(4):425-431
The Journal of dairy research 2019 Nov;86(4):425-431
Tumor-suppressive activity of Hnf1β in Wilms' tumor.
Liu Y, Kanyomse Q, Xie Y
Bioscience, biotechnology, and biochemistry 2019 Nov;83(11):2008-2015
Bioscience, biotechnology, and biochemistry 2019 Nov;83(11):2008-2015
The protective effects of L-carnitine on myocardial ischaemia-reperfusion injury in patients with rheumatic valvular heart disease undergoing CPB surgery are associated with the suppression of NF-κB pathway and the activation of Nrf2 pathway.
Li M, Xu S, Geng Y, Sun L, Wang R, Yan Y, Wang H, Li Y, Yi Q, Zhang Y, Hao J, Deng C, Li W, Xue L
Clinical and experimental pharmacology & physiology 2019 Nov;46(11):1001-1012
Clinical and experimental pharmacology & physiology 2019 Nov;46(11):1001-1012
ADP-ribosyltransferase PARP11 modulates the interferon antiviral response by mono-ADP-ribosylating the ubiquitin E3 ligase β-TrCP.
Guo T, Zuo Y, Qian L, Liu J, Yuan Y, Xu K, Miao Y, Feng Q, Chen X, Jin L, Zhang L, Dong C, Xiong S, Zheng H
Nature microbiology 2019 Nov;4(11):1872-1884
Nature microbiology 2019 Nov;4(11):1872-1884
Nonviral Delivery of GRIM-19 Gene Inhibits Tumor Growth with Reduced Local and Systemic Complications.
Xu Y, Wang X, Guo B, Wang D, Kalvakolanu DV, Chen X, Tang J, Zhang L, Yang Q
Human gene therapy 2019 Nov;30(11):1419-1430
Human gene therapy 2019 Nov;30(11):1419-1430
Long-term exposure of 4-hydroxyestradiol induces the cancer cell characteristics via upregulating CYP1B1 in MCF-10A cells.
Lanxiang W, Bin W, Ge X, Yutang H, Chunjie W, Honghao Z
Toxicology mechanisms and methods 2019 Nov;29(9):686-692
Toxicology mechanisms and methods 2019 Nov;29(9):686-692
Isoflurane produces antidepressant effects inducing BDNF-TrkB signaling in CUMS mice.
Zhang SS, Tian YH, Jin SJ, Wang WC, Zhao JX, Si XM, Zhang L, Xu H, Jin JY
Psychopharmacology 2019 Nov;236(11):3301-3315
Psychopharmacology 2019 Nov;236(11):3301-3315
Astragaloside IV alleviates myocardial damage induced by type 2 diabetes via improving energy metabolism.
Zhang Z, Wang J, Zhu Y, Zhang H, Wang H
Molecular medicine reports 2019 Nov;20(5):4612-4622
Molecular medicine reports 2019 Nov;20(5):4612-4622
Deep Protein Methylation Profiling by Combined Chemical and Immunoaffinity Approaches Reveals Novel PRMT1 Targets.
Hartel NG, Chew B, Qin J, Xu J, Graham NA
Molecular & cellular proteomics : MCP 2019 Nov;18(11):2149-2164
Molecular & cellular proteomics : MCP 2019 Nov;18(11):2149-2164
Repurposing of the anti-helminthic drug niclosamide to treat melanoma and pulmonary metastasis via the STAT3 signaling pathway.
Zhu Y, Zuo W, Chen L, Bian S, Jing J, Gan C, Wu X, Liu H, Su X, Hu W, Guo Y, Wang Y, Ye T
Biochemical pharmacology 2019 Nov;169:113610
Biochemical pharmacology 2019 Nov;169:113610
Increased Tim-3 expression alleviates liver injury by regulating macrophage activation in MCD-induced NASH mice.
Du X, Wu Z, Xu Y, Liu Y, Liu W, Wang T, Li C, Zhang C, Yi F, Gao L, Liang X, Ma C
Cellular & molecular immunology 2019 Nov;16(11):878-886
Cellular & molecular immunology 2019 Nov;16(11):878-886
LNRRIL6, a novel long noncoding RNA, protects colorectal cancer cells by activating the IL-6-STAT3 pathway.
Wang J, Zhou J, Jiang C, Zheng J, Namba H, Chi P, Asakawa T
Molecular oncology 2019 Nov;13(11):2344-2360
Molecular oncology 2019 Nov;13(11):2344-2360
Inhibition of p53 and/or AKT as a new therapeutic approach specifically targeting ALT cancers.
Ge Y, Wu S, Zhang Z, Li X, Li F, Yan S, Liu H, Huang J, Zhao Y
Protein & cell 2019 Nov;10(11):808-824
Protein & cell 2019 Nov;10(11):808-824
O-GlcNAcylation of Thr12/Ser56 in short-form O-GlcNAc transferase (sOGT) regulates its substrate selectivity.
Liu L, Li L, Ma C, Shi Y, Liu C, Xiao Z, Zhang Y, Tian F, Gao Y, Zhang J, Ying W, Wang PG, Zhang L
The Journal of biological chemistry 2019 Nov 8;294(45):16620-16633
The Journal of biological chemistry 2019 Nov 8;294(45):16620-16633
LncRNA GABPB1-AS1 and GABPB1 regulate oxidative stress during erastin-induced ferroptosis in HepG2 hepatocellular carcinoma cells.
Qi W, Li Z, Xia L, Dai J, Zhang Q, Wu C, Xu S
Scientific reports 2019 Nov 7;9(1):16185
Scientific reports 2019 Nov 7;9(1):16185
Porcine Circovirus Type 2 Induces Single Immunoglobulin Interleukin-1 Related Receptor (SIGIRR) Downregulation to Promote Interleukin-1β Upregulation in Porcine Alveolar Macrophage.
Yang S, Liu B, Yin S, Shang Y, Zhang X, Khan MUZ, Liu X, Cai J
Viruses 2019 Nov 3;11(11)
Viruses 2019 Nov 3;11(11)
Dietary Stevioside Supplementation Alleviates Lipopolysaccharide-Induced Intestinal Mucosal Damage through Anti-Inflammatory and Antioxidant Effects in Broiler Chickens.
Jiang J, Qi L, Lv Z, Jin S, Wei X, Shi F
Antioxidants (Basel, Switzerland) 2019 Nov 21;8(12)
Antioxidants (Basel, Switzerland) 2019 Nov 21;8(12)
Mulberry leaf reduces inflammation and insulin resistance in type 2 diabetic mice by TLRs and insulin Signalling pathway.
Tian S, Wang M, Liu C, Zhao H, Zhao B
BMC complementary and alternative medicine 2019 Nov 21;19(1):326
BMC complementary and alternative medicine 2019 Nov 21;19(1):326
Inhibition of PTP1B blocks pancreatic cancer progression by targeting the PKM2/AMPK/mTOC1 pathway.
Xu Q, Wu N, Li X, Guo C, Li C, Jiang B, Wang H, Shi D
Cell death & disease 2019 Nov 19;10(12):874
Cell death & disease 2019 Nov 19;10(12):874
Tissue plasminogen activator disrupts the blood-brain barrier through increasing the inflammatory response mediated by pericytes after cerebral ischemia.
Yang E, Cai Y, Yao X, Liu J, Wang Q, Jin W, Wu Q, Fan W, Qiu L, Kang C, Wu J
Aging 2019 Nov 18;11(22):10167-10182
Aging 2019 Nov 18;11(22):10167-10182
Chitosan Oligosaccharide Attenuates Nonalcoholic Fatty Liver Disease Induced by High Fat Diet through Reducing Lipid Accumulation, Inflammation and Oxidative Stress in C57BL/6 Mice.
Tao W, Sun W, Liu L, Wang G, Xiao Z, Pei X, Wang M
Marine drugs 2019 Nov 16;17(11)
Marine drugs 2019 Nov 16;17(11)
Cardioprotective effects of galectin-3 inhibition against ischemia/reperfusion injury.
Mo D, Tian W, Zhang HN, Feng YD, Sun Y, Quan W, Hao XW, Wang XY, Liu XX, Li C, Cao W, Liu WJ, Li XQ
European journal of pharmacology 2019 Nov 15;863:172701
European journal of pharmacology 2019 Nov 15;863:172701
Anti-osteoporosis effects of osteoking via reducing reactive oxygen species.
Qin D, Zhang H, Zhang H, Sun T, Zhao H, Lee WH
Journal of ethnopharmacology 2019 Nov 15;244:112045
Journal of ethnopharmacology 2019 Nov 15;244:112045
Epithelial and interstitial Notch1 activity contributes to the myofibroblastic phenotype and fibrosis.
Hong W, Zhang G, Lu H, Guo Y, Zheng S, Zhu H, Xiao Y, Papa APD, Wu C, Sun L, Chen B, Bai Y
Cell communication and signaling : CCS 2019 Nov 12;17(1):145
Cell communication and signaling : CCS 2019 Nov 12;17(1):145
Dengue Virus M Protein Promotes NLRP3 Inflammasome Activation To Induce Vascular Leakage in Mice.
Pan P, Zhang Q, Liu W, Wang W, Lao Z, Zhang W, Shen M, Wan P, Xiao F, Liu F, Zhang W, Tan Q, Liu X, Wu K, Liu Y, Li G, Wu J
Journal of virology 2019 Nov 1;93(21)
Journal of virology 2019 Nov 1;93(21)
Recombinant porcine NK-lysin inhibits the invasion of hepatocellular carcinoma cells in vitro.
Khan A, Fan K, Sun N, Yin W, Sun Y, Sun P, Jahejo AR, Li H
International journal of biological macromolecules 2019 Nov 1;140:1249-1259
International journal of biological macromolecules 2019 Nov 1;140:1249-1259
Hepatocyte nuclear factor 1 alpha (HNF1A) regulates transcription of O-GlcNAc transferase in a negative feedback mechanism.
Zhang C, Xie F, Li L, Zhang C, Zhang Y, Ying W, Liu L, Yan X, Yin F, Zhang L
FEBS letters 2019 May;593(10):1050-1060
FEBS letters 2019 May;593(10):1050-1060
Degradation of Caytaxin Causes Learning and Memory Deficits via Activation of DAPK1 in Aging.
Guo Y, Li H, Ke X, Deng M, Wu Z, Cai Y, Afewerky HK, Zhang X, Pei L, Lu Y
Molecular neurobiology 2019 May;56(5):3368-3379
Molecular neurobiology 2019 May;56(5):3368-3379
ZW290 Increases Cold Tolerance by Inducing Thermogenesis via the Upregulation of Uncoupling Protein 1 in Brown Adipose Tissue In Vitro and In Vivo.
Wang N, Lu HY, Li X, Du YJ, Meng WH, Ding HW, Zhao QC
Lipids 2019 May;54(5):265-276
Lipids 2019 May;54(5):265-276
Inhibition of PI3K/mTOR increased the sensitivity of hepatocellular carcinoma cells to cisplatin via interference with mitochondrial-lysosomal crosstalk.
Sheng J, Shen L, Sun L, Zhang X, Cui R, Wang L
Cell proliferation 2019 May;52(3):e12609
Cell proliferation 2019 May;52(3):e12609
Homeodomain-interacting protein kinase 2 suppresses proliferation and aerobic glycolysis via ERK/cMyc axis in pancreatic cancer.
Qin Y, Hu Q, Ji S, Xu J, Dai W, Liu W, Xu W, Sun Q, Zhang Z, Ni Q, Yu X, Zhang B, Xu X
Cell proliferation 2019 May;52(3):e12603
Cell proliferation 2019 May;52(3):e12603
Moderate- and Low-Dose of Atorvastatin Alleviate Cognition Impairment Induced by High-Fat Diet via Sirt1 Activation.
Liu H, Yang J, Wang K, Niu T, Huang D
Neurochemical research 2019 May;44(5):1065-1078
Neurochemical research 2019 May;44(5):1065-1078
Apoptosis and cell cycle arrest of hepatocellular carcinoma spheroids treated by an alternating electric field.
Huang CH, Lei KF, Tsang NM
Biotechnology progress 2019 May;35(3):e2787
Biotechnology progress 2019 May;35(3):e2787
[6]-Gingerol enhances the cisplatin sensitivity of gastric cancer cells through inhibition of proliferation and invasion via PI3K/AKT signaling pathway.
Luo Y, Zha L, Luo L, Chen X, Zhang Q, Gao C, Zhuang X, Yuan S, Qiao T
Phytotherapy research : PTR 2019 May;33(5):1353-1362
Phytotherapy research : PTR 2019 May;33(5):1353-1362
5-aminolevulinic acid photodynamic therapy reduces HPV viral load via autophagy and apoptosis by modulating Ras/Raf/MEK/ERK and PI3K/AKT pathways in HeLa cells.
Xie J, Wang S, Li Z, Ao C, Wang J, Wang L, Peng X, Zeng K
Journal of photochemistry and photobiology. B, Biology 2019 May;194:46-55
Journal of photochemistry and photobiology. B, Biology 2019 May;194:46-55
A novel function of anaphase promoting complex subunit 10 in tumor progression in non-small cell lung cancer.
Wang Y, Han T, Gan M, Guo M, Xie C, Jin J, Zhang S, Wang P, Cao J, Wang JB
Cell cycle (Georgetown, Tex.) 2019 May;18(9):1019-1032
Cell cycle (Georgetown, Tex.) 2019 May;18(9):1019-1032
Nano hydroxyapatite induces glioma cell apoptosis by suppressing NF-κB signaling pathway.
Guo G, Tian A, Lan X, Fu C, Yan Z, Wang C
Experimental and therapeutic medicine 2019 May;17(5):4080-4088
Experimental and therapeutic medicine 2019 May;17(5):4080-4088
Porcine circovirus type 2 ORF5 protein induces endoplasmic reticulum stress and unfolded protein response in porcine alveolar macrophages.
Ouyang Y, Xu L, Lv J, Hou Y, Fan Z, Xu P, Jiang Y, Wu M, Li R, Zhang Y, Guo K
Archives of virology 2019 May;164(5):1323-1334
Archives of virology 2019 May;164(5):1323-1334
TDP-43 induces mitochondrial damage and activates the mitochondrial unfolded protein response.
Wang P, Deng J, Dong J, Liu J, Bigio EH, Mesulam M, Wang T, Sun L, Wang L, Lee AY, McGee WA, Chen X, Fushimi K, Zhu L, Wu JY
PLoS genetics 2019 May;15(5):e1007947
PLoS genetics 2019 May;15(5):e1007947
Heat shock factor 1 in cancer-associated fibroblasts is a potential prognostic factor and drives progression of oral squamous cell carcinoma.
Wang Q, Zhang YC, Zhu LF, Pan L, Yu M, Shen WL, Li B, Zhang W, Liu LK
Cancer science 2019 May;110(5):1790-1803
Cancer science 2019 May;110(5):1790-1803
LncRNA TPT1-AS1 promotes tumorigenesis and metastasis in epithelial ovarian cancer by inducing TPT1 expression.
Wu W, Gao H, Li X, Zhu Y, Peng S, Yu J, Zhan G, Wang J, Liu N, Guo X
Cancer science 2019 May;110(5):1587-1598
Cancer science 2019 May;110(5):1587-1598
Highly Selective Protein Tyrosine Phosphatase Inhibitor, 2,2',3,3'-Tetrabromo-4,4',5,5'-tetrahydroxydiphenylmethane, Ameliorates Type 2 Diabetes Mellitus in BKS db Mice.
Li C, Luo J, Guo S, Jia X, Guo C, Li X, Xu Q, Shi D
Molecular pharmaceutics 2019 May 6;16(5):1839-1850
Molecular pharmaceutics 2019 May 6;16(5):1839-1850
Adipose HuR protects against diet-induced obesity and insulin resistance.
Li J, Gong L, Liu S, Zhang Y, Zhang C, Tian M, Lu H, Bu P, Yang J, Ouyang C, Jiang X, Wu J, Zhang Y, Min Q, Zhang C, Zhang W
Nature communications 2019 May 30;10(1):2375
Nature communications 2019 May 30;10(1):2375
Canagliflozin inhibits growth of hepatocellular carcinoma via blocking glucose-influx-induced β-catenin activation.
Hung MH, Chen YL, Chen LJ, Chu PY, Hsieh FS, Tsai MH, Shih CT, Chao TI, Huang CY, Chen KF
Cell death & disease 2019 May 29;10(6):420
Cell death & disease 2019 May 29;10(6):420
Fucoidan A2 from the Brown Seaweed Ascophyllum nodosum Lowers Lipid by Improving Reverse Cholesterol Transport in C57BL/6J Mice Fed a High-Fat Diet.
Yang Z, Liu G, Wang Y, Yin J, Wang J, Xia B, Li T, Yang X, Hou P, Hu S, Song W, Guo S
Journal of agricultural and food chemistry 2019 May 22;67(20):5782-5791
Journal of agricultural and food chemistry 2019 May 22;67(20):5782-5791
Estrogen negatively regulates the renal epithelial sodium channel (ENaC) by promoting Derlin-1 expression and AMPK activation.
Zhang X, Ge Y, Bukhari AA, Zhu Q, Shen Y, Li M, Sun H, Su D, Liang X
Experimental & molecular medicine 2019 May 21;51(5):1-12
Experimental & molecular medicine 2019 May 21;51(5):1-12
Phosphatase of regenerating liver sensitizes MET to functional activation by hepatocyte growth factor.
Kojima T, Funato Y, Miki H
The Biochemical journal 2019 May 21;476(10):1419-1431
The Biochemical journal 2019 May 21;476(10):1419-1431
Triptolide prevents proliferation and migration of Esophageal Squamous Cell Cancer via MAPK/ERK signaling pathway.
Yanchun M, Yi W, Lu W, Yu Q, Jian Y, Pengzhou K, Ting Y, Hongyi L, Fang W, Xiaolong C, Yongping C
European journal of pharmacology 2019 May 15;851:43-51
European journal of pharmacology 2019 May 15;851:43-51
Comparison of the Hepatoprotective Effects of the Three Main Stilbenes from Mulberry Twigs.
Jia YN, Peng YL, Zhao YP, Cheng XF, Zhou Y, Chai CL, Zeng LS, Pan MH, Xu L
Journal of agricultural and food chemistry 2019 May 15;67(19):5521-5529
Journal of agricultural and food chemistry 2019 May 15;67(19):5521-5529
MiR-34s negatively regulate homologous recombination through targeting RAD51.
Chen S, Liu R, Wang Q, Qi Z, Hu Y, Zhou P, Wang Z
Archives of biochemistry and biophysics 2019 May 15;666:73-82
Archives of biochemistry and biophysics 2019 May 15;666:73-82
Gambogic acid attenuates liver fibrosis by inhibiting the PI3K/AKT and MAPK signaling pathways via inhibiting HSP90.
Yu Z, Jv Y, Cai L, Tian X, Huo X, Wang C, Zhang B, Sun C, Ning J, Feng L, Zhang H, Ma X
Toxicology and applied pharmacology 2019 May 15;371:63-73
Toxicology and applied pharmacology 2019 May 15;371:63-73
Meningitic Escherichia coli-induced upregulation of PDGF-B and ICAM-1 aggravates blood-brain barrier disruption and neuroinflammatory response.
Yang RC, Qu XY, Xiao SY, Li L, Xu BJ, Fu JY, Lv YJ, Amjad N, Tan C, Kim KS, Chen HC, Wang XR
Journal of neuroinflammation 2019 May 15;16(1):101
Journal of neuroinflammation 2019 May 15;16(1):101
Sodium ferulate protects against influenza virus infection by activation of the TLR7/9-MyD88-IRF7 signaling pathway and inhibition of the NF-κB signaling pathway.
Zhu Y, Shao Y, Qu X, Guo J, Yang J, Zhou Z, Wang S
Biochemical and biophysical research communications 2019 May 14;512(4):793-798
Biochemical and biophysical research communications 2019 May 14;512(4):793-798
A maternal high-fat, high-sucrose diet induces transgenerational cardiac mitochondrial dysfunction independently of maternal mitochondrial inheritance.
Ferey JLA, Boudoures AL, Reid M, Drury A, Scheaffer S, Modi Z, Kovacs A, Pietka T, DeBosch BJ, Thompson MD, Diwan A, Moley KH
American journal of physiology. Heart and circulatory physiology 2019 May 1;316(5):H1202-H1210
American journal of physiology. Heart and circulatory physiology 2019 May 1;316(5):H1202-H1210
Histone deacetylase 7 inhibits plakoglobin expression to promote lung cancer cell growth and metastasis.
Sang Y, Sun L, Wu Y, Yuan W, Liu Y, Li SW
International journal of oncology 2019 Mar;54(3):1112-1122
International journal of oncology 2019 Mar;54(3):1112-1122
Overexpression of ERBB4 rejuvenates aged mesenchymal stem cells and enhances angiogenesis via PI3K/AKT and MAPK/ERK pathways.
Liang X, Ding Y, Lin F, Zhang Y, Zhou X, Meng Q, Lu X, Jiang G, Zhu H, Chen Y, Lian Q, Fan H, Liu Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Mar;33(3):4559-4570
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Mar;33(3):4559-4570
In utero exposure to PM2.5 during gestation caused adult cardiac hypertrophy through histone acetylation modification.
Wu X, Pan B, Liu L, Zhao W, Zhu J, Huang X, Tian J
Journal of cellular biochemistry 2019 Mar;120(3):4375-4384
Journal of cellular biochemistry 2019 Mar;120(3):4375-4384
Nuciferine inhibits the progression of glioblastoma by suppressing the SOX2-AKT/STAT3-Slug signaling pathway.
Li Z, Chen Y, An T, Liu P, Zhu J, Yang H, Zhang W, Dong T, Jiang J, Zhang Y, Jiang M, Yang X
Journal of experimental & clinical cancer research : CR 2019 Mar 29;38(1):139
Journal of experimental & clinical cancer research : CR 2019 Mar 29;38(1):139
Cysteine Dioxygenase Regulates the Epithelial Morphogenesis of Mammary Gland via Cysteine Sulfinic Acid.
Zhao J, Han Y, Ma X, Zhou Y, Yuan S, Shen Q, Ye G, Liu H, Fu P, Zhang G, Qiao B, Liu A
iScience 2019 Mar 29;13:173-189
iScience 2019 Mar 29;13:173-189
Curcumin and Resveratrol Regulate Intestinal Bacteria and Alleviate Intestinal Inflammation in Weaned Piglets.
Gan Z, Wei W, Li Y, Wu J, Zhao Y, Zhang L, Wang T, Zhong X
Molecules (Basel, Switzerland) 2019 Mar 28;24(7)
Molecules (Basel, Switzerland) 2019 Mar 28;24(7)
Effect of Stereochemical Configuration on the Transport and Metabolism of Catechins from Green Tea across Caco-2 Monolayers.
Ai Z, Liu S, Qu F, Zhang H, Chen Y, Ni D
Molecules (Basel, Switzerland) 2019 Mar 26;24(6)
Molecules (Basel, Switzerland) 2019 Mar 26;24(6)
RNA-Binding Motif Protein 24 (RBM24) Is Involved in Pregenomic RNA Packaging by Mediating Interaction between Hepatitis B Virus Polymerase and the Epsilon Element.
Yao Y, Yang B, Chen Y, Wang H, Hu X, Zhou Y, Gao X, Lu M, Niu J, Wen Z, Wu C, Chen X
Journal of virology 2019 Mar 15;93(6)
Journal of virology 2019 Mar 15;93(6)
GRASP depletion-mediated Golgi destruction decreases cell adhesion and migration via the reduction of α5β1 integrin.
Ahat E, Xiang Y, Zhang X, Bekier ME 2nd, Wang Y
Molecular biology of the cell 2019 Mar 15;30(6):766-777
Molecular biology of the cell 2019 Mar 15;30(6):766-777
The role of adenosine in up-regulation of p38 MAPK and ERK during limb ischemic preconditioning-induced brain ischemic tolerance.
Yuan Q, Jia HX, Li SQ, Xiao-Zhang, Wu YJ, Feng L, Liu XL, Sun XC, Li WB
Brain research 2019 Mar 15;1707:172-183
Brain research 2019 Mar 15;1707:172-183
Purification of cross-linked RNA-protein complexes by phenol-toluol extraction.
Urdaneta EC, Vieira-Vieira CH, Hick T, Wessels HH, Figini D, Moschall R, Medenbach J, Ohler U, Granneman S, Selbach M, Beckmann BM
Nature communications 2019 Mar 1;10(1):990
Nature communications 2019 Mar 1;10(1):990
CD30 ligand deficiency accelerates glioma progression by promoting the formation of tumor immune microenvironment.
Duan J, Gao Y, Zhang X, Wang X, Wang B, Meng X, Yoshikai Y, Wang Y, Sun X
International immunopharmacology 2019 Jun;71:350-360
International immunopharmacology 2019 Jun;71:350-360
Deficiency of ZnT8 Promotes Adiposity and Metabolic Dysfunction by Increasing Peripheral Serotonin Production.
Mao Z, Lin H, Su W, Li J, Zhou M, Li Z, Zhou B, Yang Q, Zhou M, Pan K, He J, Zhang W
Diabetes 2019 Jun;68(6):1197-1209
Diabetes 2019 Jun;68(6):1197-1209
MicroRNA-145 regulates immune cytokines via targeting FSCN1 in Staphylococcus aureus-induced mastitis in dairy cows.
Chen Z, Xu X, Tan T, Chen D, Liang H, Sun K, Li M, Zhang H, Mao Y, Yang Z
Reproduction in domestic animals = Zuchthygiene 2019 Jun;54(6):882-891
Reproduction in domestic animals = Zuchthygiene 2019 Jun;54(6):882-891
ERβ modulates genistein's cisplatin-enhancing activities in breast cancer MDA-MB-231 cells via P53-independent pathway.
Liu R, Xu X, Liang C, Chen X, Yu X, Zhong H, Xu W, Cheng Y, Wang W, Wu Y, Yu L, Hu X
Molecular and cellular biochemistry 2019 Jun;456(1-2):205-216
Molecular and cellular biochemistry 2019 Jun;456(1-2):205-216
p62 aggregates mediated Caspase 8 activation is responsible for progression of ovarian cancer.
Yan XY, Zhong XR, Yu SH, Zhang LC, Liu YN, Zhang Y, Sun LK, Su J
Journal of cellular and molecular medicine 2019 Jun;23(6):4030-4042
Journal of cellular and molecular medicine 2019 Jun;23(6):4030-4042
Age-dependent expression of the vitamin D receptor and the protective effect of vitamin D receptor activation on H2O2-induced apoptosis in rat intervertebral disc cells.
Tong T, Liu Z, Zhang H, Sun J, Zhang D, Wang F, Miao D, Shen Y
The Journal of steroid biochemistry and molecular biology 2019 Jun;190:126-138
The Journal of steroid biochemistry and molecular biology 2019 Jun;190:126-138
TUSC3 as a potential biomarker for prognosis in clear cell renal cell carcinoma.
Yan Y, Chen Z, Liao Y, Zhou J
Oncology letters 2019 Jun;17(6):5073-5079
Oncology letters 2019 Jun;17(6):5073-5079
An NLRP3 inflammasome-triggered cytokine storm contributes to Streptococcal toxic shock-like syndrome (STSLS).
Lin L, Xu L, Lv W, Han L, Xiang Y, Fu L, Jin M, Zhou R, Chen H, Zhang A
PLoS pathogens 2019 Jun;15(6):e1007795
PLoS pathogens 2019 Jun;15(6):e1007795
Decreased S1P and SPHK2 are involved in pancreatic acinar cell injury.
Xiao J, Lin H, Liu B, Xia Z, Zhang J, Jin J
Biomarkers in medicine 2019 Jun;13(8):627-637
Biomarkers in medicine 2019 Jun;13(8):627-637
A promising therapeutic option for diabetic bladder dysfunction: Adipose tissue-derived stem cells pretreated by defocused low-energy shock wave.
Zhang H, Zhao Y, Wang M, Song W, Sun P, Jin X
Journal of tissue engineering and regenerative medicine 2019 Jun;13(6):986-996
Journal of tissue engineering and regenerative medicine 2019 Jun;13(6):986-996
Recombinant human arginase I elicited immunosuppression in activated macrophages through inhibiting autophagy.
Wang Z, Song P, Li Y, Wang S, Fan J, Zhang X, Luan J, Chen W, Wang Y, Liu P, Ju D
Applied microbiology and biotechnology 2019 Jun;103(12):4825-4838
Applied microbiology and biotechnology 2019 Jun;103(12):4825-4838
Rh type C-glycoprotein functions as a novel tumor suppressor gene by inhibiting tumorigenicity and metastasis in head and neck squamous cell carcinoma.
Xu W, Zou H, Wei Z, Song C, Tang C, Yin X, Wang Y, Han S, Cai Y, Han W
Aging 2019 Jun 6;11(11):3601-3623
Aging 2019 Jun 6;11(11):3601-3623
Mechanism of Snhg8/miR-384/Hoxa13/FAM3A axis regulating neuronal apoptosis in ischemic mice model.
Liu J, An P, Xue Y, Che D, Liu X, Zheng J, Liu Y, Yang C, Li Z, Yu B
Cell death & disease 2019 Jun 5;10(6):441
Cell death & disease 2019 Jun 5;10(6):441
ROS/JNK/c-Jun axis is involved in oridonin-induced caspase-dependent apoptosis in human colorectal cancer cells.
Zhang D, Zhou Q, Huang D, He L, Zhang H, Hu B, Peng H, Ren D
Biochemical and biophysical research communications 2019 Jun 4;513(3):594-601
Biochemical and biophysical research communications 2019 Jun 4;513(3):594-601
TGF-β mediates thoracic radiation-induced abscopal effects of testis injury in rat.
Zhang J, Yao D, Zhang J, Song Y, Mo F, Chu X, Pan Y, Bai Y, Shao C
Biochemical and biophysical research communications 2019 Jun 30;514(3):678-683
Biochemical and biophysical research communications 2019 Jun 30;514(3):678-683
Chitosan Hydrogel Delivery System Containing Herbal Compound Functions as a Potential Antineuroinflammatory Agent.
Zhou J, Zheng J, Zhang Y, Zheng P, Tang T, Luo JK, Cui HJ, Song RR, Wang Y
ACS omega 2019 Jun 30;4(6):10185-10191
ACS omega 2019 Jun 30;4(6):10185-10191
UHRF1 promotes aerobic glycolysis and proliferation via suppression of SIRT4 in pancreatic cancer.
Hu Q, Qin Y, Ji S, Xu W, Liu W, Sun Q, Zhang Z, Liu M, Ni Q, Yu X, Xu X
Cancer letters 2019 Jun 28;452:226-236
Cancer letters 2019 Jun 28;452:226-236
TRIP4 promotes tumor growth and metastasis and regulates radiosensitivity of cervical cancer by activating MAPK, PI3K/AKT, and hTERT signaling.
Che Y, Li Y, Zheng F, Zou K, Li Z, Chen M, Hu S, Tian C, Yu W, Guo W, Luo M, Deng W, Zou L
Cancer letters 2019 Jun 28;452:1-13
Cancer letters 2019 Jun 28;452:1-13
Silencing of Aberrant Secretory Protein Expression by Disease-Associated Mutations.
Tikhonova EB, Karamysheva ZN, von Heijne G, Karamyshev AL
Journal of molecular biology 2019 Jun 28;431(14):2567-2580
Journal of molecular biology 2019 Jun 28;431(14):2567-2580
Organophosphorus Flame Retardants Impair Intracellular Lipid Metabolic Function in Human Hepatocellular Cells.
Hao Z, Zhang Z, Lu D, Ding B, Shu L, Zhang Q, Wang C
Chemical research in toxicology 2019 Jun 17;32(6):1250-1258
Chemical research in toxicology 2019 Jun 17;32(6):1250-1258
Blocking podoplanin suppresses growth and pulmonary metastasis of human malignant melanoma.
Xu M, Wang X, Pan Y, Zhao X, Yan B, Ruan C, Xia L, Zhao Y
BMC cancer 2019 Jun 17;19(1):599
BMC cancer 2019 Jun 17;19(1):599
Insulin transcriptionally down-regulates carboxylesterases through pregnane X receptor in an Akt-dependent manner.
Yang X, Zhang X, Liu Y, Xi T, Xiong J
Toxicology 2019 Jun 15;422:60-68
Toxicology 2019 Jun 15;422:60-68
Inhibition of Glioma Development by ASCL1-Mediated Direct Neuronal Reprogramming.
Cheng X, Tan Z, Huang X, Yuan Y, Qin S, Gu Y, Wang D, He C, Su Z
Cells 2019 Jun 11;8(6)
Cells 2019 Jun 11;8(6)
Porcine HMGCR Inhibits Porcine Circovirus Type 2 Infection by Directly Interacting with the Viral Proteins.
Ouyang T, Niu G, Zhang Y, Liu X, Zhang X, Zhang S, Geng Y, Pang D, Ouyang H, Ren L
Viruses 2019 Jun 11;11(6)
Viruses 2019 Jun 11;11(6)
Sonodynamic therapy inhibits palmitate-induced beta cell dysfunction via PINK1/Parkin-dependent mitophagy.
Guo T, Liu T, Sun Y, Liu X, Xiong R, Li H, Li Z, Zhang Z, Tian Z, Tian Y
Cell death & disease 2019 Jun 11;10(6):457
Cell death & disease 2019 Jun 11;10(6):457
Macrophage Migration Inhibitory Factor Promotes Chemotaxis of Astrocytes through Regulation of Cholesterol 25-Hydroxylase Following Rat Spinal Cord Injury.
Zhu Z, Hu Y, Zhou Y, Zhang Y, Yu L, Tao L, Guo A, Fang Q
Neuroscience 2019 Jun 1;408:349-360
Neuroscience 2019 Jun 1;408:349-360
A new split-luciferase complementation assay identifies pentachlorophenol as an inhibitor of apoptosome formation.
Tashakor A, H-Dehkordi M, O'Connell E, Gomez Ganau S, Gozalbes R, Eriksson LA, Hosseinkhani S, Fearnhead HO
FEBS open bio 2019 Jul;9(7):1194-1203
FEBS open bio 2019 Jul;9(7):1194-1203
Activation of the immunoproteasome protects SH-SY5Y cells from the toxicity of rotenone.
Sun C, Mo M, Wang Y, Yu W, Song C, Wang X, Chen S, Liu Y
Neurotoxicology 2019 Jul;73:112-119
Neurotoxicology 2019 Jul;73:112-119
Atractylodin ameliorates lipopolysaccharide and d-galactosamine-induced acute liver failure via the suppression of inflammation and oxidative stress.
Lyu Z, Ji X, Chen G, An B
International immunopharmacology 2019 Jul;72:348-357
International immunopharmacology 2019 Jul;72:348-357
MicroRNA-221 sensitizes chronic myeloid leukemia cells to imatinib by targeting STAT5.
Jiang X, Cheng Y, Hu C, Zhang A, Ren Y, Xu X
Leukemia & lymphoma 2019 Jul;60(7):1709-1720
Leukemia & lymphoma 2019 Jul;60(7):1709-1720
Epithelial ovarian cancer stem‑like cells are resistant to the cellular lysis of cytokine‑induced killer cells via HIF1A‑mediated downregulation of ICAM‑1.
Bu S, Li B, Wang Q, Gu T, Dong Q, Miao X, Lai D
International journal of oncology 2019 Jul;55(1):179-190
International journal of oncology 2019 Jul;55(1):179-190
Aspirin targets P4HA2 through inhibiting NF-κB and LMCD1-AS1/let-7g to inhibit tumour growth and collagen deposition in hepatocellular carcinoma.
Wang T, Fu X, Jin T, Zhang L, Liu B, Wu Y, Xu F, Wang X, Ye K, Zhang W, Ye L
EBioMedicine 2019 Jul;45:168-180
EBioMedicine 2019 Jul;45:168-180
Tubeimoside-1, a triterpenoid saponin, induces cytoprotective autophagy in human breast cancer cells in vitro via Akt-mediated pathway.
Jiang SL, Guan YD, Chen XS, Ge P, Wang XL, Lao YZ, Xiao SS, Zhang Y, Yang JM, Xu XJ, Cao DS, Cheng Y
Acta pharmacologica Sinica 2019 Jul;40(7):919-928
Acta pharmacologica Sinica 2019 Jul;40(7):919-928
Septin 9 isoforms promote tumorigenesis in mammary epithelial cells by increasing migration and ECM degradation through metalloproteinase secretion at focal adhesions.
Marcus J, Bejerano-Sagie M, Patterson N, Bagchi S, Verkhusha VV, Connolly D, Goldberg GL, Golden A, Sharma VP, Condeelis J, Montagna C
Oncogene 2019 Jul;38(30):5839-5859
Oncogene 2019 Jul;38(30):5839-5859
STAT3 phosphorylation mediates high glucose-impaired cell autophagy in an HDAC1-dependent and -independent manner in Schwann cells of diabetic peripheral neuropathy.
Du W, Wang N, Li F, Jia K, An J, Liu Y, Wang Y, Zhu L, Zhao S, Hao J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jul;33(7):8008-8021
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jul;33(7):8008-8021
Notch signaling activation induces cell death in MAPKi-resistant melanoma cells.
Mikheil DM, Prabhakar K, Arshad A, Rodriguez CI, Newton MA, Setaluri V
Pigment cell & melanoma research 2019 Jul;32(4):528-539
Pigment cell & melanoma research 2019 Jul;32(4):528-539
Complement C3 activation regulates the production of tRNA-derived fragments Gly-tRFs and promotes alcohol-induced liver injury and steatosis.
Zhong F, Hu Z, Jiang K, Lei B, Wu Z, Yuan G, Luo H, Dong C, Tang B, Zheng C, Yang S, Zeng Y, Guo Z, Yu S, Su H, Zhang G, Qiu X, Tomlinson S, He S
Cell research 2019 Jul;29(7):548-561
Cell research 2019 Jul;29(7):548-561
CtIP promotes G2/M arrest in etoposide-treated HCT116 cells in a p53-independent manner.
Chen H, Shan J, Chen D, Wang R, Qi W, Wang H, Ke Y, Liu W, Zeng X
Journal of cellular physiology 2019 Jul;234(7):11871-11881
Journal of cellular physiology 2019 Jul;234(7):11871-11881
DAAM1-mediated migration and invasion of ovarian cancer cells are suppressed by miR-208a-5p.
Mei J, Huang Y, Hao L, Liu Y, Yan T, Qiu T, Xu R, Xu B, Xiao Z, Jiang X, Hu K, Zhu Y
Pathology, research and practice 2019 Jul;215(7):152452
Pathology, research and practice 2019 Jul;215(7):152452
Harnessing the anti-cancer natural product nimbolide for targeted protein degradation.
Spradlin JN, Hu X, Ward CC, Brittain SM, Jones MD, Ou L, To M, Proudfoot A, Ornelas E, Woldegiorgis M, Olzmann JA, Bussiere DE, Thomas JR, Tallarico JA, McKenna JM, Schirle M, Maimone TJ, Nomura DK
Nature chemical biology 2019 Jul;15(7):747-755
Nature chemical biology 2019 Jul;15(7):747-755
Observation of novel COX20 mutations related to autosomal recessive axonal neuropathy and static encephalopathy.
Xu H, Ji T, Lian Y, Wang S, Chen X, Li S, Yin Y, Dong X
Human genetics 2019 Jul;138(7):749-756
Human genetics 2019 Jul;138(7):749-756
Low-dose PCB126 compromises circadian rhythms associated with disordered glucose and lipid metabolism in mice.
Shen X, Chen Y, Zhang J, Yan X, Liu W, Guo Y, Shan Q, Liu S
Environment international 2019 Jul;128:146-157
Environment international 2019 Jul;128:146-157
UCP2 alleviates tubular epithelial cell apoptosis in lipopolysaccharide-induced acute kidney injury by decreasing ROS production.
Zhong X, He J, Zhang X, Li C, Tian X, Xia W, Gan H, Xia Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jul;115:108914
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jul;115:108914
Roscovitine attenuates renal interstitial fibrosis in diabetic mice through the TGF-β1/p38 MAPK pathway.
Wang S, Zhou Y, Zhang Y, He X, Zhao X, Zhao H, Liu W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jul;115:108895
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jul;115:108895
Naringenin ameliorates insulin resistance by modulating endoplasmic reticulum stress in hepatitis C virus-infected liver.
Jia B, Wang Y, Yu G, Cheng Y, Yang C, Cao F, He Y, Cao P, Meng X, Yu D
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jul;115:108848
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jul;115:108848
Regulation of CD11b by HIF-1α and the STAT3 signaling pathway contributes to the immunosuppressive function of B cells in inflammatory bowel disease.
Qian T, Hong J, Wang L, Wang Z, Lu Z, Li Y, Liu R, Chu Y
Molecular immunology 2019 Jul;111:162-171
Molecular immunology 2019 Jul;111:162-171
Lysine glutarylation in human sperm is associated with progressive motility.
Cheng YM, Hu XN, Peng Z, Pan TT, Wang F, Chen HY, Chen WQ, Zhang Y, Zeng XH, Luo T
Human reproduction (Oxford, England) 2019 Jul 8;34(7):1186-1194
Human reproduction (Oxford, England) 2019 Jul 8;34(7):1186-1194
Inhibition of nucleotide synthesis promotes replicative senescence of human mammary epithelial cells.
Delfarah A, Parrish S, Junge JA, Yang J, Seo F, Li S, Mac J, Wang P, Fraser SE, Graham NA
The Journal of biological chemistry 2019 Jul 5;294(27):10564-10578
The Journal of biological chemistry 2019 Jul 5;294(27):10564-10578
A novel hydrogen sulfide-releasing donor, HA-ADT, suppresses the growth of human breast cancer cells through inhibiting the PI3K/AKT/mTOR and Ras/Raf/MEK/ERK signaling pathways.
Dong Q, Yang B, Han JG, Zhang MM, Liu W, Zhang X, Yu HL, Liu ZG, Zhang SH, Li T, Wu DD, Ji XY, Duan SF
Cancer letters 2019 Jul 28;455:60-72
Cancer letters 2019 Jul 28;455:60-72
Lingguizhugan decoction attenuates diet-induced obesity and hepatosteatosis via gut microbiota.
Liu MT, Huang YJ, Zhang TY, Tan LB, Lu XF, Qin J
World journal of gastroenterology 2019 Jul 21;25(27):3590-3606
World journal of gastroenterology 2019 Jul 21;25(27):3590-3606
Hypoxia inducible factor 1α in vascular smooth muscle cells promotes angiotensin II-induced vascular remodeling via activation of CCL7-mediated macrophage recruitment.
Qi D, Wei M, Jiao S, Song Y, Wang X, Xie G, Taranto J, Liu Y, Duan Y, Yu B, Li H, Shah YM, Xu Q, Du J, Gonzalez FJ, Qu A
Cell death & disease 2019 Jul 18;10(8):544
Cell death & disease 2019 Jul 18;10(8):544
AcMNPV PKIP is associated with nucleocapsid of budded virions and involved in nucleocapsid assembly.
Lai Q, Zhu L, Xu L, Yuan M, Wu W, Yang K
Virus research 2019 Jul 15;268:27-37
Virus research 2019 Jul 15;268:27-37
CUL7 E3 Ubiquitin Ligase Mediates the Degradation of Activation-Induced Cytidine Deaminase and Regulates the Ig Class Switch Recombination in B Lymphocytes.
Luo Y, Liu Y, Wu L, Ma X, Liu Q, Huang F, Zhang X, Zhang Y, Zhang J, Luo H, Yang Y, Lu G, Tang X, Li L, Zeng Y, Pan T, Zhang H
Journal of immunology (Baltimore, Md. : 1950) 2019 Jul 1;203(1):269-281
Journal of immunology (Baltimore, Md. : 1950) 2019 Jul 1;203(1):269-281
Tri-ortho-cresyl phosphate (TOCP) induced ovarian failure in mice is related to the Hippo signaling pathway disruption.
Hu L, Peng T, Huang J, Su T, Luo R, Zheng Y, Zhong Z, Yu P, Nie K, Zheng L
Reproductive toxicology (Elmsford, N.Y.) 2019 Jan;83:21-27
Reproductive toxicology (Elmsford, N.Y.) 2019 Jan;83:21-27
Autocrine secretions enhance radioresistance in an exosome‑independent manner in NSCLC cells.
Wang S, Gao P, Li N, Chen P, Wang J, He N, Ji K, Du L, Liu Q
International journal of oncology 2019 Jan;54(1):229-238
International journal of oncology 2019 Jan;54(1):229-238
miR-132-3p boosts caveolae-mediated transcellular transport in glioma endothelial cells by targeting PTEN/PI3K/PKB/Src/Cav-1 signaling pathway.
Gu Y, Cai R, Zhang C, Xue Y, Pan Y, Wang J, Zhang Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jan;33(1):441-454
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jan;33(1):441-454
Plant-derived alkaloid sinomenine potentiates glucocorticoid pharmacodynamics in mitogen-activated human peripheral blood mononuclear cells by regulating the translocation of glucocorticoid receptor.
Xu W, Wang X, Tu Y, Masaki H, Tanaka S, Onda K, Sugiyama K, Yamada H, Hirano T
Phytotherapy research : PTR 2019 Jan;33(1):187-196
Phytotherapy research : PTR 2019 Jan;33(1):187-196
MMP-9 Upregulation is Attenuated by the Monoclonal TLR2 Antagonist T2.5 After Oxygen-Glucose Deprivation and Reoxygenation in Rat Brain Microvascular Endothelial Cells.
Zhu H, Dai R, Fu H, Meng Q
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2019 Jan;28(1):97-106
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2019 Jan;28(1):97-106
Function of BRD4 in the pathogenesis of high glucose‑induced cardiac hypertrophy.
Wang Q, Sun Y, Li T, Liu L, Zhao Y, Li L, Zhang L, Meng Y
Molecular medicine reports 2019 Jan;19(1):499-507
Molecular medicine reports 2019 Jan;19(1):499-507
SVIP alleviates CCl4-induced liver fibrosis via activating autophagy and protecting hepatocytes.
Jia D, Wang YY, Wang P, Huang Y, Liang DY, Wang D, Cheng C, Zhang C, Guo L, Liang P, Wang Y, Jia Y, Li C
Cell death & disease 2019 Jan 25;10(2):71
Cell death & disease 2019 Jan 25;10(2):71
LncRNA SNHG12 inhibits miR-199a to upregulate SIRT1 to attenuate cerebral ischemia/reperfusion injury through activating AMPK signaling pathway.
Yin WL, Yin WG, Huang BS, Wu LX
Neuroscience letters 2019 Jan 18;690:188-195
Neuroscience letters 2019 Jan 18;690:188-195
Reciprocal regulation of integrin β4 and KLF4 promotes gliomagenesis through maintaining cancer stem cell traits.
Ma B, Zhang L, Zou Y, He R, Wu Q, Han C, Zhang B
Journal of experimental & clinical cancer research : CR 2019 Jan 18;38(1):23
Journal of experimental & clinical cancer research : CR 2019 Jan 18;38(1):23
MMP13 inhibition rescues cognitive decline in Alzheimer transgenic mice via BACE1 regulation.
Zhu BL, Long Y, Luo W, Yan Z, Lai YJ, Zhao LG, Zhou WH, Wang YJ, Shen LL, Liu L, Deng XJ, Wang XF, Sun F, Chen GJ
Brain : a journal of neurology 2019 Jan 1;142(1):176-192
Brain : a journal of neurology 2019 Jan 1;142(1):176-192
Mechanism underlying the retarded nuclear translocation of androgen receptor splice variants.
Liu Y, Wang Y, Wang F, Pan J, Xu J, Li J, Zhou C, Ding G, Wu Y, Liu X, Sheng J, Huang H
Science China. Life sciences 2019 Feb;62(2):257-267
Science China. Life sciences 2019 Feb;62(2):257-267
Sodium rutin ameliorates Alzheimer's disease-like pathology by enhancing microglial amyloid-β clearance.
Pan RY, Ma J, Kong XX, Wang XF, Li SS, Qi XL, Yan YH, Cheng J, Liu Q, Jin W, Tan CH, Yuan Z
Science advances 2019 Feb;5(2):eaau6328
Science advances 2019 Feb;5(2):eaau6328
Nucleoporin 107 facilitates the nuclear export of Scn5a mRNA to regulate cardiac bioelectricity.
Guan Y, Gao X, Tang Q, Huang L, Gao S, Yu S, Huang J, Li J, Zhou D, Zhang Y, Shi D, Liang D, Liu Y, Li L, Cui Y, Xu L, Chen YH
Journal of cellular and molecular medicine 2019 Feb;23(2):1448-1457
Journal of cellular and molecular medicine 2019 Feb;23(2):1448-1457
Effects of Fluoride on Autophagy in Mouse Sertoli Cells.
Feng Z, Liang C, Manthari RK, Wang C, Zhang J
Biological trace element research 2019 Feb;187(2):499-505
Biological trace element research 2019 Feb;187(2):499-505
CDK11p110 plays a critical role in the tumorigenicity of esophageal squamous cell carcinoma cells and is a potential drug target.
Du Y, Yan D, Yuan Y, Xu J, Wang S, Yang Z, Cheng W, Tian X, Kan Q
Cell cycle (Georgetown, Tex.) 2019 Feb;18(4):452-466
Cell cycle (Georgetown, Tex.) 2019 Feb;18(4):452-466
Intestinal non-canonical NFκB signaling shapes the local and systemic immune response.
Ramakrishnan SK, Zhang H, Ma X, Jung I, Schwartz AJ, Triner D, Devenport SN, Das NK, Xue X, Zeng MY, Hu Y, Mortensen RM, Greenson JK, Cascalho M, Wobus CE, Colacino JA, Nunez G, Rui L, Shah YM
Nature communications 2019 Feb 8;10(1):660
Nature communications 2019 Feb 8;10(1):660
Dietary canolol induces apoptosis in human cervical carcinoma HeLa cells through ROS-MAPK mediated mitochondrial signaling pathway: In vitro and in vivo.
Xia X, Xiang X, Huang F, Zheng M, Zhang Z, Han L
Chemico-biological interactions 2019 Feb 25;300:138-150
Chemico-biological interactions 2019 Feb 25;300:138-150
Kibra Modulates Learning and Memory via Binding to Dendrin.
Ji Z, Li H, Yang Z, Huang X, Ke X, Ma S, Lin Z, Lu Y, Zhang M
Cell reports 2019 Feb 19;26(8):2064-2077.e7
Cell reports 2019 Feb 19;26(8):2064-2077.e7
miR-33 and RIP140 participate in LPS-induced acute lung injury
Li H, Hou H, Liu S, Feng Y, Zhong W, Hu X, Yan N
Turkish journal of medical sciences 2019 Feb 11;49(1):422-428
Turkish journal of medical sciences 2019 Feb 11;49(1):422-428
Gene expression profile-based drug screen identifies SAHA as a novel treatment for NAFLD.
Cheng Z, Wen Y, Liang B, Chen S, Liu Y, Wang Z, Cheng J, Tang X, Xin H, Deng L
Molecular omics 2019 Feb 11;15(1):50-58
Molecular omics 2019 Feb 11;15(1):50-58
The Autographa californica Multiple Nucleopolyhedrovirus ac51 Gene Is Required for Efficient Nuclear Egress of Nucleocapsids and Is Essential for In Vivo Virulence.
Qiu J, Tang Z, Cai Y, Wu W, Yuan M, Yang K
Journal of virology 2019 Feb 1;93(3)
Journal of virology 2019 Feb 1;93(3)
SRT1720 retards renal fibrosis via inhibition of HIF1α /GLUT1 in diabetic nephropathy.
Han W, Wang C, Yang Z, Mu L, Wu M, Chen N, Du C, Duan H, Shi Y
The Journal of endocrinology 2019 Feb 1;
The Journal of endocrinology 2019 Feb 1;
JAK2/STAT1-mediated HMGB1 translocation increases inflammation and cell death in a ventilator-induced lung injury model.
Liu Q, Xie W, Wang Y, Chen S, Han J, Wang L, Gui P, Wu Q
Laboratory investigation; a journal of technical methods and pathology 2019 Dec;99(12):1810-1821
Laboratory investigation; a journal of technical methods and pathology 2019 Dec;99(12):1810-1821
LncRNA SNHG4 promotes the proliferation, migration, invasiveness, and epithelial-mesenchymal transition of lung cancer cells by regulating miR-98-5p.
Tang Y, Wu L, Zhao M, Zhao G, Mao S, Wang L, Liu S, Wang X
Biochemistry and cell biology = Biochimie et biologie cellulaire 2019 Dec;97(6):767-776
Biochemistry and cell biology = Biochimie et biologie cellulaire 2019 Dec;97(6):767-776
NO donor inhibits proliferation and induces apoptosis by targeting PI3K/AKT/mTOR and MEK/ERK pathways in hepatocellular carcinoma cells.
Liu L, Chen J, Cao M, Wang J, Wang S
Cancer chemotherapy and pharmacology 2019 Dec;84(6):1303-1314
Cancer chemotherapy and pharmacology 2019 Dec;84(6):1303-1314
Carpesium abrotanoides (L.) Root as a Potential Source of Natural Anticancer Compounds: Targeting Glucose Metabolism and PKM2/HIF-1α Axis of Breast Cancer Cells.
Chai XX, Le YF, Wang JC, Mei CX, Feng JF, Zhao H, Wang C, Lu DZ
Journal of food science 2019 Dec;84(12):3825-3832
Journal of food science 2019 Dec;84(12):3825-3832
Indoxyl sulfate-induced calcification of vascular smooth muscle cells via the PI3K/Akt/NF-κB signaling pathway.
He X, Jiang H, Gao F, Liang S, Wei M, Chen L
Microscopy research and technique 2019 Dec;82(12):2000-2006
Microscopy research and technique 2019 Dec;82(12):2000-2006
Peroxisome Proliferator-Activated Receptors (PPARs) levels in spermatozoa of normozoospermic and asthenozoospermic men.
Mousavi MS, Shahverdi A, Drevet J, Akbarinejad V, Esmaeili V, Sayahpour FA, Topraggaleh TR, Rahimizadeh P, Alizadeh A
Systems biology in reproductive medicine 2019 Dec;65(6):409-419
Systems biology in reproductive medicine 2019 Dec;65(6):409-419
LncRNA-241 inhibits 1,2-Dichloroethane-induced hepatic apoptosis.
Zeng N, Zhang Z, Jiang H, Li R, Chang C, Wang F, Xu D, Fan Q, Wang T, Xiao Y, Chen W, Shan Z, Huang Z, Wang Q
Toxicology in vitro : an international journal published in association with BIBRA 2019 Dec;61:104650
Toxicology in vitro : an international journal published in association with BIBRA 2019 Dec;61:104650
Lipopolysaccharide-induced DNA damage response activates nuclear factor κB signalling pathway via GATA4 in dental pulp cells.
Qiao W, Huang Y, Bian Z, Sun X, Wang X, Gao Q, Peng Y, Meng L
International endodontic journal 2019 Dec;52(12):1704-1715
International endodontic journal 2019 Dec;52(12):1704-1715
Transcriptome sequencing of Eospalax fontanierii to determine hypoxia regulation of cardiac fibrinogen.
Xu L, Hao Z, Lin J, Zhao Q, Zhang B, Li G, He J, Li J
Molecular biology reports 2019 Dec;46(6):5671-5683
Molecular biology reports 2019 Dec;46(6):5671-5683
Dysregulated Transcription Factor TFAP2A After Peripheral Nerve Injury Modulated Schwann Cell Phenotype.
Zhang F, Gu X, Yi S, Xu H
Neurochemical research 2019 Dec;44(12):2776-2785
Neurochemical research 2019 Dec;44(12):2776-2785
ORP4L couples IP3 to ITPR1 in control of endoplasmic reticulum calcium release.
Cao X, Chen J, Li D, Xie P, Xu M, Lin W, Li S, Pan G, Tang Y, Xu J, Olkkonen VM, Yan D, Zhong W
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Dec;33(12):13852-13865
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Dec;33(12):13852-13865
Base pair editing in goat: nonsense codon introgression into FGF5 results in longer hair.
Li G, Zhou S, Li C, Cai B, Yu H, Ma B, Huang Y, Ding Y, Liu Y, Ding Q, He C, Zhou J, Wang Y, Zhou G, Li Y, Yan Y, Hua J, Petersen B, Jiang Y, Sonstegard T, Huang X, Chen Y, Wang X
The FEBS journal 2019 Dec;286(23):4675-4692
The FEBS journal 2019 Dec;286(23):4675-4692
Rotenone protects against β-cell apoptosis and attenuates type 1 diabetes mellitus.
Wu M, Chen W, Zhang S, Huang S, Zhang A, Zhang Y, Jia Z
Apoptosis : an international journal on programmed cell death 2019 Dec;24(11-12):879-891
Apoptosis : an international journal on programmed cell death 2019 Dec;24(11-12):879-891
S100A9 regulates porcine reproductive and respiratory syndrome virus replication by interacting with the viral nucleocapsid protein.
Song Z, Bai J, Liu X, Nauwynck H, Wu J, Liu X, Jiang P
Veterinary microbiology 2019 Dec;239:108498
Veterinary microbiology 2019 Dec;239:108498
Tandem repeat sequence of duck circovirus serves as downstream sequence element to regulate viral gene expression.
Wu ZC, Xia XJ, Li HR, Jiang SJ, Ma ZY, Wang X
Veterinary microbiology 2019 Dec;239:108496
Veterinary microbiology 2019 Dec;239:108496
miR-451a inhibits cancer growth, epithelial-mesenchymal transition and induces apoptosis in papillary thyroid cancer by targeting PSMB8.
Fan X, Zhao Y
Journal of cellular and molecular medicine 2019 Dec;23(12):8067-8075
Journal of cellular and molecular medicine 2019 Dec;23(12):8067-8075
Punicalagin Reversed the Hepatic Injury of Tetrachloromethane by Antioxidation and Enhancement of Autophagy.
Luo J, Long Y, Ren G, Zhang Y, Chen J, Huang R, Yang L
Journal of medicinal food 2019 Dec;22(12):1271-1279
Journal of medicinal food 2019 Dec;22(12):1271-1279
Hypoxia enhances IL-10-producing B cell generation through upregulating high-mobility group B1 on tumor cell-released autophagosomes.
Zhang Y, Pan N, Sheng Y, Zhou M, Wen Z, Chen Y, Huang F, Wang LX
Immunology letters 2019 Dec;216:36-42
Immunology letters 2019 Dec;216:36-42
Novel sphingomyelin biomarkers for brain glioma and associated regulation research on the PI3K/Akt signaling pathway.
Zhai XH, Xiao J, Yu JK, Sun H, Zheng S
Oncology letters 2019 Dec;18(6):6207-6213
Oncology letters 2019 Dec;18(6):6207-6213
Catalpol alleviates adriamycin-induced nephropathy by activating the SIRT1 signalling pathway in vivo and in vitro.
Zhang J, Bi R, Meng Q, Wang C, Huo X, Liu Z, Wang C, Sun P, Sun H, Ma X, Wu J, Liu K
British journal of pharmacology 2019 Dec;176(23):4558-4573
British journal of pharmacology 2019 Dec;176(23):4558-4573
HDAC11 restricts HBV replication through epigenetic repression of cccDNA transcription.
Yuan Y, Zhao K, Yao Y, Liu C, Chen Y, Li J, Wang Y, Pei R, Chen J, Hu X, Zhou Y, Wu C, Chen X
Antiviral research 2019 Dec;172:104619
Antiviral research 2019 Dec;172:104619
BECN1 promotes the migration of NSCLC cells through regulating the ubiquitination of Vimentin.
Cheng Z, Xin H, Han T
Cell adhesion & migration 2019 Dec;13(1):249-259
Cell adhesion & migration 2019 Dec;13(1):249-259
Xiaoerfupi alleviates the symptoms of functional dyspepsia by regulating the HTR3A and c-FOS.
Ji E, Wang T, Guo F, Zhang Y, Tang C, Tang D, Wei J, Yang H, Xian M
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109442
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109442
Pleiotropic Effects of Epithelial Mesenchymal Crosstalk on Head and Neck Cancer: EMT and beyond.
Steinbichler TB, Savic D, Dejaco D, Romani A, Kofler B, Skvortsova II, Riechelmann H, Dudas J
Cancer microenvironment : official journal of the International Cancer Microenvironment Society 2019 Dec;12(2-3):67-76
Cancer microenvironment : official journal of the International Cancer Microenvironment Society 2019 Dec;12(2-3):67-76
Endocytic degradation of ErbB2 mediates the effectiveness of neratinib in the suppression of ErbB2-positive ovarian cancer.
Wang S, Zhang J, Wang T, Ren F, Liu X, Lu Y, Xu L, Zhang Y, Wang D, Xu L, Wu Y, Liu F, Li Q, Zaky MY, Liu S, Dong W, Liu F, Zou K, Zhang Y
The international journal of biochemistry & cell biology 2019 Dec;117:105640
The international journal of biochemistry & cell biology 2019 Dec;117:105640
Curcumin inhibits LPS-induced neuroinflammation by promoting microglial M2 polarization via TREM2/ TLR4/ NF-κB pathways in BV2 cells.
Zhang J, Zheng Y, Luo Y, Du Y, Zhang X, Fu J
Molecular immunology 2019 Dec;116:29-37
Molecular immunology 2019 Dec;116:29-37
Critical roles of NLRP3 inflammasome in IL-1β secretion induced by Corynebacterium pseudotuberculosis in vitro.
Zhou Z, Li H, Tian S, Yi W, Zhou Y, Yang H, Li X, Wu B, Li X, Wu J, Wang Z, Hu S, Fang R
Molecular immunology 2019 Dec;116:11-17
Molecular immunology 2019 Dec;116:11-17
Activating macrophages for enhanced osteogenic and bactericidal performance by Cu ion release from micro/nano-topographical coating on a titanium substrate.
Huang Q, Ouyang Z, Tan Y, Wu H, Liu Y
Acta biomaterialia 2019 Dec;100:415-426
Acta biomaterialia 2019 Dec;100:415-426
Oral Administration of Succinoglycan Riclin Improves Diet-Induced Hypercholesterolemia in Mice.
Yang Y, Sun Q, Xu X, Yang X, Gao Y, Sun X, Zhao Y, Ding Z, Ge W, Cheng R, Zhang J
Journal of agricultural and food chemistry 2019 Dec 4;67(48):13307-13317
Journal of agricultural and food chemistry 2019 Dec 4;67(48):13307-13317
Yes-associated protein regulates podocyte cell cycle re-entry and dedifferentiation in adriamycin-induced nephropathy.
Xie K, Xu C, Zhang M, Wang M, Min L, Qian C, Wang Q, Ni Z, Mou S, Dai H, Pang H, Gu L
Cell death & disease 2019 Dec 4;10(12):915
Cell death & disease 2019 Dec 4;10(12):915
Sal B Alleviates Myocardial Ischemic Injury by Inhibiting TLR4 and the Priming Phase of NLRP3 Inflammasome.
Hu Y, Li Q, Pan Y, Xu L
Molecules (Basel, Switzerland) 2019 Dec 3;24(23)
Molecules (Basel, Switzerland) 2019 Dec 3;24(23)
Hydrogen sulfide attenuates mitochondrial dysfunction-induced cellular senescence and apoptosis in alveolar epithelial cells by upregulating sirtuin 1.
Guan R, Cai Z, Wang J, Ding M, Li Z, Xu J, Li Y, Li J, Yao H, Liu W, Qian J, Deng B, Tang C, Sun D, Lu W
Aging 2019 Dec 23;11(24):11844-11864
Aging 2019 Dec 23;11(24):11844-11864
Beneficial Effects of Ticagrelor on Oxidized Low-Density Lipoprotein (ox-LDL)-Induced Apoptosis in Human Umbilical Vein Endothelial Cells.
Kang M, Shao S, Zhang Y, Liang X, Zhang K, Li G
Medical science monitor : international medical journal of experimental and clinical research 2019 Dec 21;25:9811-9819
Medical science monitor : international medical journal of experimental and clinical research 2019 Dec 21;25:9811-9819
RASAL1 induces to downregulate the SCD1, leading to suppression of cell proliferation in colon cancer via LXRα/SREBP1c pathway.
Wang G, Li Z, Li X, Zhang C, Peng L
Biological research 2019 Dec 17;52(1):60
Biological research 2019 Dec 17;52(1):60
Stasimon Contributes to the Loss of Sensory Synapses and Motor Neuron Death in a Mouse Model of Spinal Muscular Atrophy.
Simon CM, Van Alstyne M, Lotti F, Bianchetti E, Tisdale S, Watterson DM, Mentis GZ, Pellizzoni L
Cell reports 2019 Dec 17;29(12):3885-3901.e5
Cell reports 2019 Dec 17;29(12):3885-3901.e5
Gdf11 gene transfer prevents high fat diet-induced obesity and improves metabolic homeostasis in obese and STZ-induced diabetic mice.
Lu B, Zhong J, Pan J, Yuan X, Ren M, Jiang L, Yang Y, Zhang G, Liu D, Zhang C
Journal of translational medicine 2019 Dec 17;17(1):422
Journal of translational medicine 2019 Dec 17;17(1):422
Integration of transcriptomics and network analysis deciphers the mechanisms of baicalein in improving learning and memory impairment in senescence-accelerated mouse prone 8 (SAMP8).
Li J, Zhou Y, Du G, Qin X, Gao L
European journal of pharmacology 2019 Dec 15;865:172789
European journal of pharmacology 2019 Dec 15;865:172789
Rafoxanide promotes apoptosis and autophagy of gastric cancer cells by suppressing PI3K /Akt/mTOR pathway.
Liu JZ, Hu YL, Feng Y, Guo YB, Liu YF, Yang JL, Mao QS, Xue WJ
Experimental cell research 2019 Dec 15;385(2):111691
Experimental cell research 2019 Dec 15;385(2):111691
PI3K/Akt inhibitor partly decreases TNF-α-induced activation of fibroblast-like synoviocytes in osteoarthritis.
Liu S, Cao C, Zhang Y, Liu G, Ren W, Ye Y, Sun T
Journal of orthopaedic surgery and research 2019 Dec 11;14(1):425
Journal of orthopaedic surgery and research 2019 Dec 11;14(1):425
Aptamer-Based Erythrocyte-Derived Mimic Vesicles Loaded with siRNA and Doxorubicin for the Targeted Treatment of Multidrug-Resistant Tumors.
Wang T, Luo Y, Lv H, Wang J, Zhang Y, Pei R
ACS applied materials & interfaces 2019 Dec 11;11(49):45455-45466
ACS applied materials & interfaces 2019 Dec 11;11(49):45455-45466
7-O-geranylquercetin contributes to reverse P-gp-mediated adriamycin resistance in breast cancer.
Zhang E, Liu J, Shi L, Guo X, Liang Z, Zuo J, Xu H, Wang H, Shu X, Huang S, Zhang S, Kang X, Zhen Y
Life sciences 2019 Dec 1;238:116938
Life sciences 2019 Dec 1;238:116938
Fe3O4@OA@Poloxamer nanoparticles lower triglyceride in hepatocytes through liposuction effect and nano-enzyme effect.
Sun Y, Shi F, Niu Y, Zhang Y, Xiong F
Colloids and surfaces. B, Biointerfaces 2019 Dec 1;184:110528
Colloids and surfaces. B, Biointerfaces 2019 Dec 1;184:110528
Abnormal expression of Pappa2 gene may indirectly affect mouse hip development through the IGF signaling pathway.
Chen Y, Li L, Wang E, Zhang L, Zhao Q
Endocrine 2019 Aug;65(2):440-450
Endocrine 2019 Aug;65(2):440-450
MIF/CD74 axis participates in inflammatory activation of Schwann cells following sciatic nerve injury.
Song H, Zhu Z, Zhou Y, Du N, Song T, Liang H, Chen X, Wang Y, Wang Y, Hu Y
Journal of molecular histology 2019 Aug;50(4):355-367
Journal of molecular histology 2019 Aug;50(4):355-367
In Vitro Infectious Risk Assessment of Heliothis virescens ascovirus 3j (HvAV-3j) toward Non-target Vertebrate Cells.
Yu H, Ou-Yang YY, Li N, Nakai M, Huang GH
Virologica Sinica 2019 Aug;34(4):423-433
Virologica Sinica 2019 Aug;34(4):423-433
PLZF regulates apoptosis of leukemia cells by regulating AKT/Foxo3a pathway.
Li JX, Zhang ZF, Wang XB, Yang EQ, Dong L, Meng J
European review for medical and pharmacological sciences 2019 Aug;23(15):6411-6418
European review for medical and pharmacological sciences 2019 Aug;23(15):6411-6418
The effects of fluorene-9-bisphenol on female zebrafish (Danio rerio) reproductive and exploratory behaviors.
Mi P, Zhang QP, Zhang SH, Wang C, Zhang SZ, Fang YC, Gao JZ, Feng DF, Chen DY, Feng XZ
Chemosphere 2019 Aug;228:398-411
Chemosphere 2019 Aug;228:398-411
17β‑Estradiol protects against interleukin‑1β‑induced apoptosis in rat nucleus pulposus cells via the mTOR/caspase‑3 pathway.
Guo HT, Yang SD, Zhang F, Liu S, Yang DL, Ma L, Wang H, Ding WY
Molecular medicine reports 2019 Aug;20(2):1523-1530
Molecular medicine reports 2019 Aug;20(2):1523-1530
Proteomic Analysis Reveals that Odoroside A Triggers G2/M Arrest and Apoptosis in Colorectal Carcinoma Through ROS-p53 Pathway.
Chen YY, Wen SY, Deng CM, Yin XF, Sun ZH, Jiang MM, He QY
Proteomics 2019 Aug;19(15):e1900092
Proteomics 2019 Aug;19(15):e1900092
Diosgenin regulates cholesterol metabolism in hypercholesterolemic rats by inhibiting NPC1L1 and enhancing ABCG5 and ABCG8.
Li R, Liu Y, Shi J, Yu Y, Lu H, Yu L, Liu Y, Zhang F
Biochimica et biophysica acta. Molecular and cell biology of lipids 2019 Aug;1864(8):1124-1133
Biochimica et biophysica acta. Molecular and cell biology of lipids 2019 Aug;1864(8):1124-1133
HSF1 phosphorylation by cyclosporin A confers hyperthermia sensitivity through suppression of HSP expression.
Shao J, Han B, Cao P, Zhang B, Liu M, Li D, Zhou N, Hao Q, Duan X, Chang Y, Nakai A, Fan Y, Tan K
Biochimica et biophysica acta. Gene regulatory mechanisms 2019 Aug;1862(8):846-857
Biochimica et biophysica acta. Gene regulatory mechanisms 2019 Aug;1862(8):846-857
Sesterterpene MHO7 suppresses breast cancer cells as a novel estrogen receptor degrader.
Zhao Y, Zhao C, Lu J, Wu J, Li C, Hu Z, Tian W, Yang L, Xiang J, Zhou H, Deng Z, Huang J, Hong K
Pharmacological research 2019 Aug;146:104294
Pharmacological research 2019 Aug;146:104294
Proteomic analysis of murine bone marrow derived dendritic cells in response to peste des petits ruminants virus.
Li L, Wu J, Cao X, Zhou J, Yin S, Yang S, Feng Q, Du P, Liu Y, Shang Y, Liu Y, Liu X
Research in veterinary science 2019 Aug;125:195-204
Research in veterinary science 2019 Aug;125:195-204
Involvement of microRNA-23b-5p in the promotion of cardiac hypertrophy and dysfunction via the HMGB2 signaling pathway.
Boureima Oumarou D, Ji H, Xu J, Li S, Ruan W, Xiao F, Yu F
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Aug;116:108977
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Aug;116:108977
Interleukin-1 receptor associated kinase (IRAK)-M -mediated type 2 microglia polarization ameliorates the severity of experimental autoimmune encephalomyelitis (EAE).
Liu B, Gu Y, Pei S, Peng Y, Chen J, Pham LV, Shen HY, Zhang J, Wang H
Journal of autoimmunity 2019 Aug;102:77-88
Journal of autoimmunity 2019 Aug;102:77-88
USP49 potently stabilizes APOBEC3G protein by removing ubiquitin and inhibits HIV-1 replication.
Pan T, Song Z, Wu L, Liu G, Ma X, Peng Z, Zhou M, Liang L, Liu B, Liu J, Zhang J, Zhang X, Huang R, Zhao J, Li Y, Ling X, Luo Y, Tang X, Cai W, Deng K, Li L, Zhang H
eLife 2019 Aug 9;8
eLife 2019 Aug 9;8
Bone marrow-derived mesenchymal stromal cells promote resistance to tyrosine kinase inhibitors in chronic myeloid leukemia via the IL-7/JAK1/STAT5 pathway.
Zhang X, Tu H, Yang Y, Jiang X, Hu X, Luo Q, Li J
The Journal of biological chemistry 2019 Aug 9;294(32):12167-12179
The Journal of biological chemistry 2019 Aug 9;294(32):12167-12179
Stimulation of endothelial progenitor cells by microRNA-31a-5p to induce endothelialization in an aneurysm neck after coil embolization by modulating the Axin1-mediated β-catenin/vascular endothelial growth factor pathway.
Yu G, Liu P, Shi Y, Li S, Liu Y, Fan Z, Zhu W
Journal of neurosurgery 2019 Aug 9;:1-9
Journal of neurosurgery 2019 Aug 9;:1-9
ANLN-induced EZH2 upregulation promotes pancreatic cancer progression by mediating miR-218-5p/LASP1 signaling axis.
Wang A, Dai H, Gong Y, Zhang C, Shu J, Luo Y, Jiang Y, Liu W, Bie P
Journal of experimental & clinical cancer research : CR 2019 Aug 8;38(1):347
Journal of experimental & clinical cancer research : CR 2019 Aug 8;38(1):347
Jingfukang induces anti-cancer activity through oxidative stress-mediated DNA damage in circulating human lung cancer cells.
Que Z, Zhou Z, Luo B, Dong C, Jiang Y, Li H, Tian J
BMC complementary and alternative medicine 2019 Aug 7;19(1):204
BMC complementary and alternative medicine 2019 Aug 7;19(1):204
Platelet-Membrane-Camouflaged Black Phosphorus Quantum Dots Enhance Anticancer Effect Mediated by Apoptosis and Autophagy.
Shang Y, Wang Q, Wu B, Zhao Q, Li J, Huang X, Chen W, Gui R
ACS applied materials & interfaces 2019 Aug 7;11(31):28254-28266
ACS applied materials & interfaces 2019 Aug 7;11(31):28254-28266
Epigenetic Memory Is Involved in the Persistent Alterations of Drug-Processing Genes in Adult Mice due to PCN-Activated PXR during Early Life.
Wang P, Liu G, Nie Y, Han S, Li J, Zhong XB, Zhang L
Toxicological sciences : an official journal of the Society of Toxicology 2019 Aug 6;
Toxicological sciences : an official journal of the Society of Toxicology 2019 Aug 6;
Large-conductance calcium-activated potassium channels mediate lipopolysaccharide-induced activation of murine microglia.
Yang X, Wang G, Cao T, Zhang L, Ma Y, Jiang S, Teng X, Sun X
The Journal of biological chemistry 2019 Aug 30;294(35):12921-12932
The Journal of biological chemistry 2019 Aug 30;294(35):12921-12932
ORMDL3 knockdown in the lungs alleviates airway inflammation and airway remodeling in asthmatic mice via JNK1/2-MMP-9 pathway.
Wang H, Liu Y, Shi J, Cheng Z
Biochemical and biophysical research communications 2019 Aug 27;516(3):739-746
Biochemical and biophysical research communications 2019 Aug 27;516(3):739-746
Glial response in early stages of traumatic brain injury.
Zhao J, Wang B, Huang T, Guo X, Yang Z, Song J, Zhang M
Neuroscience letters 2019 Aug 24;708:134335
Neuroscience letters 2019 Aug 24;708:134335
Divergent engagements between adeno-associated viruses with their cellular receptor AAVR.
Zhang R, Xu G, Cao L, Sun Z, He Y, Cui M, Sun Y, Li S, Li H, Qin L, Hu M, Yuan Z, Rao Z, Ding W, Rao Z, Lou Z
Nature communications 2019 Aug 21;10(1):3760
Nature communications 2019 Aug 21;10(1):3760
BMAL1 Disrupted Intrinsic Diurnal Oscillation in Rat Cerebrovascular Contractility of Simulated Microgravity Rats by Altering Circadian Regulation of miR-103/CaV1.2 Signal Pathway.
Chen L, Zhang B, Yang L, Bai YG, Song JB, Ge YL, Ma HZ, Cheng JH, Ma J, Xie MJ
International journal of molecular sciences 2019 Aug 14;20(16)
International journal of molecular sciences 2019 Aug 14;20(16)
Induction of Fibroblast Senescence During Mouse Corneal Wound Healing.
Wang X, Qu M, Li J, Danielson P, Yang L, Zhou Q
Investigative ophthalmology & visual science 2019 Aug 1;60(10):3669-3679
Investigative ophthalmology & visual science 2019 Aug 1;60(10):3669-3679
The fucoidan A3 from the seaweed Ascophyllum nodosum enhances RCT-related genes expression in hyperlipidemic C57BL/6J mice.
Yang Z, Yin J, Wang Y, Wang J, Xia B, Li T, Yang X, Hu S, Ji C, Guo S
International journal of biological macromolecules 2019 Aug 1;134:759-769
International journal of biological macromolecules 2019 Aug 1;134:759-769
The fucoidan from the brown seaweed Ascophyllum nodosum ameliorates atherosclerosis in apolipoprotein E-deficient mice.
Yin J, Wang J, Li F, Yang Z, Yang X, Sun W, Xia B, Li T, Song W, Guo S
Food & function 2019 Aug 1;10(8):5124-5139
Food & function 2019 Aug 1;10(8):5124-5139
The status of ω-3 PUFAs influence chronic unpredicted mild stress-induced metabolic side effects in rats through INSIG/SREBP pathway.
Tang M, Floyd S, Cai H, Zhang M, Yang R, Dang R
Food & function 2019 Aug 1;10(8):4649-4660
Food & function 2019 Aug 1;10(8):4649-4660
LncRNA THOR increases osteosarcoma cell stemness and migration by enhancing SOX9 mRNA stability.
Wu H, He Y, Chen H, Liu Y, Wei B, Chen G, Lin H, Lin H
FEBS open bio 2019 Apr;9(4):781-790
FEBS open bio 2019 Apr;9(4):781-790
Nerve growth factor prevents arsenic-induced toxicity in PC12 cells through the AKT/GSK-3β/NFAT pathway.
Tan Z, Kang T, Zhang X, Tong Y, Chen S
Journal of cellular physiology 2019 Apr;234(4):4726-4738
Journal of cellular physiology 2019 Apr;234(4):4726-4738
NLRP3 inflammasome plays an important role in caspase-1 activation and IL-1β secretion in macrophages infected with Pasteurella multocida.
Fang R, Du H, Lei G, Liu Y, Feng S, Ye C, Li N, Peng Y
Veterinary microbiology 2019 Apr;231:207-213
Veterinary microbiology 2019 Apr;231:207-213
Curcumin exerts cytotoxicity dependent on reactive oxygen species accumulation in non-small-cell lung cancer cells.
Wang C, Song X, Shang M, Zou W, Zhang M, Wei H, Shao H
Future oncology (London, England) 2019 Apr;15(11):1243-1253
Future oncology (London, England) 2019 Apr;15(11):1243-1253
Downregulation of RGMA by HIF-1A/miR-210-3p axis promotes cell proliferation in oral squamous cell carcinoma.
Lu Y, Li Y, Wang Z, Xie S, Wang Q, Lei X, Ruan Y, Li J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Apr;112:108608
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Apr;112:108608
Aspirin ameliorates lung cancer by targeting the miR-98/WNT1 axis.
Gan H, Lin L, Hu N, Yang Y, Gao Y, Pei Y, Chen K, Sun B
Thoracic cancer 2019 Apr;10(4):744-750
Thoracic cancer 2019 Apr;10(4):744-750
Human cells are permissive for the productive infection of porcine circovirus type 2 in vitro.
Liu X, Ouyang T, Ouyang H, Liu X, Niu G, Huo W, Yin W, Pang D, Ren L
Scientific reports 2019 Apr 4;9(1):5638
Scientific reports 2019 Apr 4;9(1):5638
LncRNA SNHG20 predicts a poor prognosis and promotes cell progression in epithelial ovarian cancer.
Wang D, Dai J, Hou S, Qian Y
Bioscience reports 2019 Apr 30;39(4)
Bioscience reports 2019 Apr 30;39(4)
UBE2C functions as a potential oncogene by enhancing cell proliferation, migration, invasion, and drug resistance in hepatocellular carcinoma cells.
Xiong Y, Lu J, Fang Q, Lu Y, Xie C, Wu H, Yin Z
Bioscience reports 2019 Apr 30;39(4)
Bioscience reports 2019 Apr 30;39(4)
Excessive miR-25-3p maturation via N6-methyladenosine stimulated by cigarette smoke promotes pancreatic cancer progression.
Zhang J, Bai R, Li M, Ye H, Wu C, Wang C, Li S, Tan L, Mai D, Li G, Pan L, Zheng Y, Su J, Ye Y, Fu Z, Zheng S, Zuo Z, Liu Z, Zhao Q, Che X, Xie D, Jia W, Zeng MS, Tan W, Chen R, Xu RH, Zheng J, Lin D
Nature communications 2019 Apr 23;10(1):1858
Nature communications 2019 Apr 23;10(1):1858
Icariin attenuates neuroinflammation and exerts dopamine neuroprotection via an Nrf2-dependent manner.
Zhang B, Wang G, He J, Yang Q, Li D, Li J, Zhang F
Journal of neuroinflammation 2019 Apr 22;16(1):92
Journal of neuroinflammation 2019 Apr 22;16(1):92
Ntrk1 Promotes Resistance to PD-1 Checkpoint Blockade in Mesenchymal Kras/p53 Mutant Lung Cancer.
Konen JM, Rodriguez BL, Fradette JJ, Gibson L, Davis D, Minelli R, Peoples MD, Kovacs J, Carugo A, Bristow C, Heffernan T, Gibbons DL
Cancers 2019 Apr 2;11(4)
Cancers 2019 Apr 2;11(4)
Macrophage migration inhibitory factor facilitates prostaglandin E2 production of astrocytes to tune inflammatory milieu following spinal cord injury.
Zhang Y, Zhou Y, Chen S, Hu Y, Zhu Z, Wang Y, Du N, Song T, Yang Y, Guo A, Wang Y
Journal of neuroinflammation 2019 Apr 13;16(1):85
Journal of neuroinflammation 2019 Apr 13;16(1):85
MicroRNA-106b Regulates Milk Fat Metabolism via ATP Binding Cassette Subfamily A Member 1 ( ABCA1) in Bovine Mammary Epithelial Cells.
Chen Z, Chu S, Wang X, Fan Y, Zhan T, Arbab AAI, Li M, Zhang H, Mao Y, Loor JJ, Yang Z
Journal of agricultural and food chemistry 2019 Apr 10;67(14):3981-3990
Journal of agricultural and food chemistry 2019 Apr 10;67(14):3981-3990
Immunomodulatory effects of an acidic polysaccharide fraction from herbal Gynostemma pentaphyllum tea in RAW264.7 cells.
Ren D, Zhao Y, Zheng Q, Alim A, Yang X
Food & function 2019 Apr 1;10(4):2186-2197
Food & function 2019 Apr 1;10(4):2186-2197
Exosomal ephrinA2 derived from serum as a potential biomarker for prostate cancer.
Li S, Zhao Y, Chen W, Yin L, Zhu J, Zhang H, Cai C, Li P, Huang L, Ma P
Journal of Cancer 2018;9(15):2659-2665
Journal of Cancer 2018;9(15):2659-2665
AMPH-1 is critical for breast cancer progression.
Chen Y, Liu J, Li L, Xia H, Lin Z, Zhong T
Journal of Cancer 2018;9(12):2175-2182
Journal of Cancer 2018;9(12):2175-2182
The Protective Effect of Astaxanthin on Cognitive Function via Inhibition of Oxidative Stress and Inflammation in the Brains of Chronic T2DM Rats.
Feng Y, Chu A, Luo Q, Wu M, Shi X, Chen Y
Frontiers in pharmacology 2018;9:748
Frontiers in pharmacology 2018;9:748
Maternal Protein Restriction Induces Alterations in Hepatic Unfolded Protein Response-Related Molecules in Adult Rat Offspring.
Liu X, Wang J, Gao L, Jiao Y, Liu C
Frontiers in endocrinology 2018;9:676
Frontiers in endocrinology 2018;9:676
β-TrCP Restricts Lipopolysaccharide (LPS)-Induced Activation of TRAF6-IKK Pathway Upstream of IκBα Signaling.
Liu J, Yuan Y, Xu J, Xiao K, Xu Y, Guo T, Zhang L, Wang J, Zheng H
Frontiers in immunology 2018;9:2930
Frontiers in immunology 2018;9:2930
The Host Restriction Factor Interferon-Inducible Transmembrane Protein 3 Inhibits Vaccinia Virus Infection.
Li C, Du S, Tian M, Wang Y, Bai J, Tan P, Liu W, Yin R, Wang M, Jiang Y, Li Y, Zhu N, Zhu Y, Li T, Wu S, Jin N, He F
Frontiers in immunology 2018;9:228
Frontiers in immunology 2018;9:228
Protective Effect of Extract of Bletilla Striata on Isoflurane Induced Neuronal Injury By Altering PI3K/Akt Pathway.
Zhao G, Li K, Chen J, Li L
Translational neuroscience 2018;9:183-189
Translational neuroscience 2018;9:183-189
Magnolol Alleviates Inflammatory Responses and Lipid Accumulation by AMP-Activated Protein Kinase-Dependent Peroxisome Proliferator-Activated Receptor α Activation.
Tian Y, Feng H, Han L, Wu L, Lv H, Shen B, Li Z, Zhang Q, Liu G
Frontiers in immunology 2018;9:147
Frontiers in immunology 2018;9:147
Geniposide and Chlorogenic Acid Combination Ameliorates Non-alcoholic Steatohepatitis Involving the Protection on the Gut Barrier Function in Mouse Induced by High-Fat Diet.
Peng JH, Leng J, Tian HJ, Yang T, Fang Y, Feng Q, Zhao Y, Hu YY
Frontiers in pharmacology 2018;9:1399
Frontiers in pharmacology 2018;9:1399
Oncolytic Newcastle disease virus induces autophagy-dependent immunogenic cell death in lung cancer cells.
Ye T, Jiang K, Wei L, Barr MP, Xu Q, Zhang G, Ding C, Meng S, Piao H
American journal of cancer research 2018;8(8):1514-1527
American journal of cancer research 2018;8(8):1514-1527
Add-On therapy with Chinese herb medicine Bo-Er-Ning capsule (BENC) improves outcomes of gastric cancer patients: a randomized clinical trial followed with bioinformatics-assisted mechanism study.
Pan B, Zang J, He J, Wang Z, Liu L
American journal of cancer research 2018;8(6):1090-1105
American journal of cancer research 2018;8(6):1090-1105
Liposomal Curcumin Targeting Endometrial Cancer Through the NF-κB Pathway.
Xu H, Gong Z, Zhou S, Yang S, Wang D, Chen X, Wu J, Liu L, Zhong S, Zhao J, Tang J
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;48(2):569-582
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;48(2):569-582
Placental growth factor promotes epithelial-mesenchymal transition-like changes in ARPE-19 cells under hypoxia.
Zhang Y, Zhao L, Wang L, Yang X, Zhou A, Wang J
Molecular vision 2018;24:340-352
Molecular vision 2018;24:340-352
Dorsal Root Ganglion Maintains Stemness of Bone Marrow Mesenchymal Stem Cells by Enhancing Autophagy through the AMPK/mTOR Pathway in a Coculture System.
Zhang S, Li J, Jiang H, Gao Y, Cheng P, Cao T, Li D, Wang J, Song Y, Liu B, Wu H, Wang C, Yang L, Pei G
Stem cells international 2018;2018:8478953
Stem cells international 2018;2018:8478953
Glucagon-Like Peptide-1 Mediates the Protective Effect of the Dipeptidyl Peptidase IV Inhibitor on Renal Fibrosis via Reducing the Phenotypic Conversion of Renal Microvascular Cells in Monocrotaline-Treated Rats.
Xu J, Wang J, Cheng Y, Li X, He M, Zhu J, Han H, Wei G, Kong H, Xie W, Wang H, Zuo X
BioMed research international 2018;2018:1864107
BioMed research international 2018;2018:1864107
Oxidative stress and NF-κB signaling are involved in LPS induced pulmonary dysplasia in chick embryos.
Long Y, Wang G, Li K, Zhang Z, Zhang P, Zhang J, Zhang X, Bao Y, Yang X, Wang P
Cell cycle (Georgetown, Tex.) 2018;17(14):1757-1771
Cell cycle (Georgetown, Tex.) 2018;17(14):1757-1771
Foot-and-mouth disease virus capsid protein VP2 activates the cellular EIF2S1-ATF4 pathway and induces autophagy via HSPB1.
Sun P, Zhang S, Qin X, Chang X, Cui X, Li H, Zhang S, Gao H, Wang P, Zhang Z, Luo J, Li Z
Autophagy 2018;14(2):336-346
Autophagy 2018;14(2):336-346
TRIM59 regulates autophagy through modulating both the transcription and the ubiquitination of BECN1.
Han T, Guo M, Gan M, Yu B, Tian X, Wang JB
Autophagy 2018;14(12):2035-2048
Autophagy 2018;14(12):2035-2048
Linagliptin unmasks specific antioxidant pathways protective against albuminuria and kidney hypertrophy in a mouse model of diabetes.
Spencer NY, Yang Z, Sullivan JC, Klein T, Stanton RC
PloS one 2018;13(7):e0200249
PloS one 2018;13(7):e0200249
Dysregulation of Neuregulin-1/ErbB signaling in the hippocampus of rats after administration of doxorubicin.
Liao D, Guo Y, Xiang D, Dang R, Xu P, Cai H, Cao L, Jiang P
Drug design, development and therapy 2018;12:231-239
Drug design, development and therapy 2018;12:231-239
Involvement of microRNA-146a in diabetic peripheral neuropathy through the regulation of inflammation.
Feng Y, Chen L, Luo Q, Wu M, Chen Y, Shi X
Drug design, development and therapy 2018;12:171-177
Drug design, development and therapy 2018;12:171-177
Expression and significance of the Hedgehog signal transduction pathway in oxygen-induced retinal neovascularization in mice.
Liu M, Chen X, Liu H, Di Y
Drug design, development and therapy 2018;12:1337-1346
Drug design, development and therapy 2018;12:1337-1346
miR-222-3p promotes osteosarcoma cell migration and invasion through targeting TIMP3.
Guo J, Liu Q, Li Z, Guo H, Bai C, Wang F
OncoTargets and therapy 2018;11:8643-8653
OncoTargets and therapy 2018;11:8643-8653
Protective Effect of Hydrogen on Sodium Iodate-Induced Age-Related Macular Degeneration in Mice.
Liu Y, Li R, Xie J, Hu J, Huang X, Ren F, Li L
Frontiers in aging neuroscience 2018;10:389
Frontiers in aging neuroscience 2018;10:389
Dl-3-n-Butylphthalide improves lipopolysaccharide-induced depressive-like behavior in rats: involvement of Nrf2 and NF-κB pathways.
Yang M, Dang R, Xu P, Guo Y, Han W, Liao D, Jiang P
Psychopharmacology 2018 Sep;235(9):2573-2585
Psychopharmacology 2018 Sep;235(9):2573-2585
miR-34b-5p inhibition attenuates lung inflammation and apoptosis in an LPS-induced acute lung injury mouse model by targeting progranulin.
Xie W, Lu Q, Wang K, Lu J, Gu X, Zhu D, Liu F, Guo Z
Journal of cellular physiology 2018 Sep;233(9):6615-6631
Journal of cellular physiology 2018 Sep;233(9):6615-6631
Amyotrophic lateral sclerosis (ALS) and Alzheimer's disease (AD) are characterised by differential activation of ER stress pathways: focus on UPR target genes.
Montibeller L, de Belleroche J
Cell stress & chaperones 2018 Sep;23(5):897-912
Cell stress & chaperones 2018 Sep;23(5):897-912
Exosomal zinc transporter ZIP4 promotes cancer growth and is a novel diagnostic biomarker for pancreatic cancer.
Jin H, Liu P, Wu Y, Meng X, Wu M, Han J, Tan X
Cancer science 2018 Sep;109(9):2946-2956
Cancer science 2018 Sep;109(9):2946-2956
Disruption of Tmem30a results in cerebellar ataxia and degeneration of Purkinje cells.
Yang Y, Sun K, Liu W, Zhang L, Peng K, Zhang S, Li S, Yang M, Jiang Z, Lu F, Zhu X
Cell death & disease 2018 Sep 5;9(9):899
Cell death & disease 2018 Sep 5;9(9):899
The regulatory effects of metformin on the [SNAIL/miR-34]:[ZEB/miR-200] system in the epithelial-mesenchymal transition(EMT) for colorectal cancer(CRC).
Wang Y, Wu Z, Hu L
European journal of pharmacology 2018 Sep 5;834:45-53
European journal of pharmacology 2018 Sep 5;834:45-53
Targeting Epigenetic Crosstalk as a Therapeutic Strategy for EZH2-Aberrant Solid Tumors.
Huang X, Yan J, Zhang M, Wang Y, Chen Y, Fu X, Wei R, Zheng XL, Liu Z, Zhang X, Yang H, Hao B, Shen YY, Su Y, Cong X, Huang M, Tan M, Ding J, Geng M
Cell 2018 Sep 20;175(1):186-199.e19
Cell 2018 Sep 20;175(1):186-199.e19
Transcriptomic but not genomic variability confers phenotype of breast cancer stem cells.
Tong M, Deng Z, Yang M, Xu C, Zhang X, Zhang Q, Liao Y, Deng X, Lv D, Zhang X, Zhang Y, Li P, Song L, Wang B, Al-Dherasi A, Li Z, Liu Q
Cancer communications (London, England) 2018 Sep 19;38(1):56
Cancer communications (London, England) 2018 Sep 19;38(1):56
Cattle Encephalon Glycoside and Ignotin Reduce Early Brain Injury and Cognitive Dysfunction after Subarachnoid Hemorrhage in Rats.
Ma K, Li R, Zhao H, Qu J, Mu N, Liu X, Wang S, Yang C, Feng H, Tan L, Li F
Neuroscience 2018 Sep 15;388:181-190
Neuroscience 2018 Sep 15;388:181-190
Cutting Edge: Dysregulated CARD9 Signaling in Neutrophils Drives Inflammation in a Mouse Model of Neutrophilic Dermatoses.
Tartey S, Gurung P, Samir P, Burton A, Kanneganti TD
Journal of immunology (Baltimore, Md. : 1950) 2018 Sep 15;201(6):1639-1644
Journal of immunology (Baltimore, Md. : 1950) 2018 Sep 15;201(6):1639-1644
Resveratrol Suppresses Matrix Metalloproteinase-2 Activation Induced by Lipopolysaccharide in Mouse Osteoblasts via Interactions with AMP-Activated Protein Kinase and Suppressor of Cytokine Signaling 1.
Yu Y, Li X, Mi J, Qu L, Yang D, Guo J, Qiu L
Molecules (Basel, Switzerland) 2018 Sep 12;23(9)
Molecules (Basel, Switzerland) 2018 Sep 12;23(9)
The apoptosis in arsenic-induced oxidative stress is associated with autophagy in the testis tissues of chicken.
Shao YZ, Zhao HJ, Wang Y, Liu JJ, Li JL, Luo LY, Xing MW
Poultry science 2018 Sep 1;97(9):3248-3257
Poultry science 2018 Sep 1;97(9):3248-3257
Dipeptidyl peptidase IV (DPP-4) inhibition alleviates pulmonary arterial remodeling in experimental pulmonary hypertension.
Xu J, Wang J, He M, Han H, Xie W, Wang H, Kong H
Laboratory investigation; a journal of technical methods and pathology 2018 Oct;98(10):1333-1346
Laboratory investigation; a journal of technical methods and pathology 2018 Oct;98(10):1333-1346
Bone morphogenetic protein 4 expression in the developing lumbosacral spinal cord of rat embryos with anorectal malformations.
Yang Z, Jia H, Bai Y, Wang W
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 2018 Oct;69:32-38
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 2018 Oct;69:32-38
MicroRNA-543 functions as an osteogenesis promoter in human periodontal ligament-derived stem cells by inhibiting transducer of ERBB2, 2.
Ge Y, Li J, Hao Y, Hu Y, Chen D, Wu B, Fang F
Journal of periodontal research 2018 Oct;53(5):832-841
Journal of periodontal research 2018 Oct;53(5):832-841
Curcumol induces RIPK1/RIPK3 complex-dependent necroptosis via JNK1/2-ROS signaling in hepatic stellate cells.
Jia Y, Wang F, Guo Q, Li M, Wang L, Zhang Z, Jiang S, Jin H, Chen A, Tan S, Zhang F, Shao J, Zheng S
Redox biology 2018 Oct;19:375-387
Redox biology 2018 Oct;19:375-387
Quantitative Global Proteome and Lysine Succinylome Analyses Reveal the Effects of Energy Metabolism in Renal Cell Carcinoma.
Zhang N, Gao R, Yang J, Zhu Y, Zhang Z, Xu X, Wang J, Liu X, Li Z, Li Z, Gong D, Li J, Bi J, Kong C
Proteomics 2018 Oct;18(19):e1800001
Proteomics 2018 Oct;18(19):e1800001
Salidroside attenuates endothelial cellular senescence via decreasing the expression of inflammatory cytokines and increasing the expression of SIRT3.
Xing SS, Li J, Chen L, Yang YF, He PL, Li J, Yang J
Mechanisms of ageing and development 2018 Oct;175:1-6
Mechanisms of ageing and development 2018 Oct;175:1-6
TRIM65 supports bladder urothelial carcinoma cell aggressiveness by promoting ANXA2 ubiquitination and degradation.
Wei WS, Chen X, Guo LY, Li XD, Deng MH, Yuan GJ, He LY, Li YH, Zhang ZL, Jiang LJ, Chen RX, Ma XD, Wei S, Ma NF, Liu ZW, Luo JH, Zhou FJ, Xie D
Cancer letters 2018 Oct 28;435:10-22
Cancer letters 2018 Oct 28;435:10-22
Cyclophilin J limits inflammation through the blockage of ubiquitin chain sensing.
Sheng C, Yao C, Wang Z, Chen H, Zhao Y, Xu D, Huang H, Huang W, Chen S
Nature communications 2018 Oct 22;9(1):4381
Nature communications 2018 Oct 22;9(1):4381
Berberrubine and its analog, hydroxypropyl-berberrubine, regulate LDLR and PCSK9 expression via the ERK signal pathway to exert cholesterol-lowering effects in human hepatoma HepG2 cells.
Cao S, Xu P, Yan J, Liu H, Liu L, Cheng L, Qiu F, Kang N
Journal of cellular biochemistry 2018 Oct 18;
Journal of cellular biochemistry 2018 Oct 18;
Apelin-13 Upregulates BDNF Against Chronic Stress-induced Depression-like Phenotypes by Ameliorating HPA Axis and Hippocampal Glucocorticoid Receptor Dysfunctions.
Dai TT, Wang B, Xiao ZY, You Y, Tian SW
Neuroscience 2018 Oct 15;390:151-159
Neuroscience 2018 Oct 15;390:151-159
Reduced graphene oxide triggered epithelial-mesenchymal transition in A549 cells.
Liao Y, Wang W, Huang X, Sun Y, Tian S, Cai P
Scientific reports 2018 Oct 12;8(1):15188
Scientific reports 2018 Oct 12;8(1):15188
Andrographolide inhibits breast cancer through suppressing COX-2 expression and angiogenesis via inactivation of p300 signaling and VEGF pathway.
Peng Y, Wang Y, Tang N, Sun D, Lan Y, Yu Z, Zhao X, Feng L, Zhang B, Jin L, Yu F, Ma X, Lv C
Journal of experimental & clinical cancer research : CR 2018 Oct 12;37(1):248
Journal of experimental & clinical cancer research : CR 2018 Oct 12;37(1):248
SUMO-1 modification of FEN1 facilitates its interaction with Rad9-Rad1-Hus1 to counteract DNA replication stress.
Xu X, Shi R, Zheng L, Guo Z, Wang L, Zhou M, Zhao Y, Tian B, Truong K, Chen Y, Shen B, Hua Y, Xu H
Journal of molecular cell biology 2018 Oct 1;10(5):460-474
Journal of molecular cell biology 2018 Oct 1;10(5):460-474
Fluoride induces apoptosis and autophagy through the IL-17 signaling pathway in mice hepatocytes.
Zhao Y, Li Y, Wang J, Manthari RK, Wang J
Archives of toxicology 2018 Nov;92(11):3277-3289
Archives of toxicology 2018 Nov;92(11):3277-3289
Atorvastatin Pretreatment Attenuates Ischemic Brain Edema by Suppressing Aquaporin 4.
Cheng ZJ, Dai TM, Shen YY, He JL, Li J, Tu JL
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2018 Nov;27(11):3247-3255
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2018 Nov;27(11):3247-3255
Oncogenic activation of PI3K induces progenitor cell differentiation to suppress epidermal growth.
Ying Z, Sandoval M, Beronja S
Nature cell biology 2018 Nov;20(11):1256-1266
Nature cell biology 2018 Nov;20(11):1256-1266
(2R,3R)Dihydromyricetin inhibits osteoclastogenesis and bone loss through scavenging LPS-induced oxidative stress and NF-κB and MAPKs pathways activating.
Zhang X, Li X, Fang J, Hou X, Fang H, Guo F, Li F, Chen A, Huang S
Journal of cellular biochemistry 2018 Nov;119(11):8981-8995
Journal of cellular biochemistry 2018 Nov;119(11):8981-8995
NR2B-Tyr phosphorylation regulates synaptic plasticity in central sensitization in a chronic migraine rat model.
Wang XY, Zhou HR, Wang S, Liu CY, Qin GC, Fu QQ, Zhou JY, Chen LX
The journal of headache and pain 2018 Nov 6;19(1):102
The journal of headache and pain 2018 Nov 6;19(1):102
MicroRNA-32 Regulates Development and Progression of Hepatocellular Carcinoma by Targeting ADAMTS9 and Affects Its Prognosis.
Li S, Li T, Li X, Yao Y, Jiang X, Zhao L, Guo W
Medical science monitor basic research 2018 Nov 5;24:177-187
Medical science monitor basic research 2018 Nov 5;24:177-187
Zinc finger E-box-binding homeobox 1 mediates aerobic glycolysis via suppression of sirtuin 3 in pancreatic cancer.
Xu WY, Hu QS, Qin Y, Zhang B, Liu WS, Ni QX, Xu J, Yu XJ
World journal of gastroenterology 2018 Nov 21;24(43):4893-4905
World journal of gastroenterology 2018 Nov 21;24(43):4893-4905
Estrogen receptor β upregulated by lncRNA-H19 to promote cancer stem-like properties in papillary thyroid carcinoma.
Li M, Chai HF, Peng F, Meng YT, Zhang LZ, Zhang L, Zou H, Liang QL, Li MM, Mao KG, Sun DX, Tong MY, Deng ZQ, Hou ZJ, Zhao Y, Li J, Wang XC, Lv SS, Zhang QQ, Yu X, Lam EW, Liu Q, Cui XN, Xu J
Cell death & disease 2018 Nov 2;9(11):1120
Cell death & disease 2018 Nov 2;9(11):1120
Citrus Tangeretin Improves Skeletal Muscle Mitochondrial Biogenesis via Activating the AMPK-PGC1-α Pathway In Vitro and In Vivo: A Possible Mechanism for Its Beneficial Effect on Physical Performance.
Kou G, Li Z, Wu C, Liu Y, Hu Y, Guo L, Xu X, Zhou Z
Journal of agricultural and food chemistry 2018 Nov 14;66(45):11917-11925
Journal of agricultural and food chemistry 2018 Nov 14;66(45):11917-11925
Nitric oxide triggers the assembly of "type II" stress granules linked to decreased cell viability.
Aulas A, Lyons SM, Fay MM, Anderson P, Ivanov P
Cell death & disease 2018 Nov 13;9(11):1129
Cell death & disease 2018 Nov 13;9(11):1129
Inhibitor of Bruton's tyrosine kinases, PCI-32765, decreases pro-inflammatory mediators' production in high glucose-induced macrophages.
Fan Z, Wang Y, Xu X, Wu Y
International immunopharmacology 2018 May;58:145-153
International immunopharmacology 2018 May;58:145-153
Overexpression of collagen type V α1 chain in human breast invasive ductal carcinoma is mediated by TGF-β1.
Ren W, Zhang Y, Zhang L, Lin Q, Zhang J, Xu G
International journal of oncology 2018 May;52(5):1694-1704
International journal of oncology 2018 May;52(5):1694-1704
Establishment of a human embryonic stem cell line with homozygous TP53 R248W mutant by TALEN mediated gene editing.
Xu A, Zhou R, Tu J, Huo Z, Zhu D, Wang D, Gingold JA, Mata H, Rao PH, Liu M, Mohamed AMT, Kong CSL, Jewell BE, Xia W, Zhao R, Hung MC, Lee DF
Stem cell research 2018 May;29:215-219
Stem cell research 2018 May;29:215-219
Induction of OTUD1 by RNA viruses potently inhibits innate immune responses by promoting degradation of the MAVS/TRAF3/TRAF6 signalosome.
Zhang L, Liu J, Qian L, Feng Q, Wang X, Yuan Y, Zuo Y, Cheng Q, Miao Y, Guo T, Zheng X, Zheng H
PLoS pathogens 2018 May;14(5):e1007067
PLoS pathogens 2018 May;14(5):e1007067
Systemic administration of scAAV9-IGF1 extends survival in SOD1G93A ALS mice via inhibiting p38 MAPK and the JNK-mediated apoptosis pathway.
Wang W, Wen D, Duan W, Yin J, Cui C, Wang Y, Li Z, Liu Y, Li C
Brain research bulletin 2018 May;139:203-210
Brain research bulletin 2018 May;139:203-210
Exogenous leptin affects sperm parameters and impairs blood testis barrier integrity in adult male mice.
Wang X, Zhang X, Hu L, Li H
Reproductive biology and endocrinology : RB&E 2018 May 31;16(1):55
Reproductive biology and endocrinology : RB&E 2018 May 31;16(1):55
IRF8 Regulates Transcription of Naips for NLRC4 Inflammasome Activation.
Karki R, Lee E, Place D, Samir P, Mavuluri J, Sharma BR, Balakrishnan A, Malireddi RKS, Geiger R, Zhu Q, Neale G, Kanneganti TD
Cell 2018 May 3;173(4):920-933.e13
Cell 2018 May 3;173(4):920-933.e13
Effect of propolis on preserving human periodontal ligament cells and regulating pro-inflammatory cytokines.
Yuan XJ, Wang YY, Shi BQ, Zhao YM
Dental traumatology : official publication of International Association for Dental Traumatology 2018 May 27;
Dental traumatology : official publication of International Association for Dental Traumatology 2018 May 27;
Hepatoprotection of auraptene from peels of citrus fruits against thioacetamide-induced hepatic fibrosis in mice by activating farnesoid X receptor.
Gao X, Wang C, Ning C, Liu K, Wang X, Liu Z, Sun H, Ma X, Sun P, Meng Q
Food & function 2018 May 23;9(5):2684-2694
Food & function 2018 May 23;9(5):2684-2694
TRIM50 suppressed hepatocarcinoma progression through directly targeting SNAIL for ubiquitous degradation.
Ma X, Ma X, Qiu Y, Zhu L, Lin Y, You Y, Ma D, Qin Z, Sun C, Zhao Y, Sun Y, Han L
Cell death & disease 2018 May 22;9(6):608
Cell death & disease 2018 May 22;9(6):608
Renal protective effect of Paeoniflorin by inhibition of JAK2/STAT3 signaling pathway in diabetic mice.
Li X, Wang Y, Wang K, Wu Y
Bioscience trends 2018 May 13;12(2):168-176
Bioscience trends 2018 May 13;12(2):168-176
Cell Cycle Regulation by Alternative Polyadenylation of CCND1.
Wang Q, He G, Hou M, Chen L, Chen S, Xu A, Fu Y
Scientific reports 2018 May 1;8(1):6824
Scientific reports 2018 May 1;8(1):6824
Dietary α-Mangostin Provides Protective Effects against Acetaminophen-Induced Hepatotoxicity in Mice via Akt/mTOR-Mediated Inhibition of Autophagy and Apoptosis.
Yan XT, Sun YS, Ren S, Zhao LC, Liu WC, Chen C, Wang Z, Li W
International journal of molecular sciences 2018 May 1;19(5)
International journal of molecular sciences 2018 May 1;19(5)
ASK1/2 signaling promotes inflammation in a mouse model of neutrophilic dermatosis.
Tartey S, Gurung P, Dasari TK, Burton A, Kanneganti TD
The Journal of clinical investigation 2018 May 1;128(5):2042-2047
The Journal of clinical investigation 2018 May 1;128(5):2042-2047
Innately activated TLR4 signal in the nucleus accumbens is sustained by CRF amplification loop and regulates impulsivity.
Balan I, Warnock KT, Puche A, Gondre-Lewis MC, Aurelian L
Brain, behavior, and immunity 2018 Mar;69:139-153
Brain, behavior, and immunity 2018 Mar;69:139-153
Effects of gelling bath on the physical properties of alginate gel beads and the biological characteristics of entrapped HepG2 cells.
Sun D, Liu Y, Wu H, Ren Y, Ma X, Wu H, Sun G
Biotechnology and applied biochemistry 2018 Mar;65(2):263-273
Biotechnology and applied biochemistry 2018 Mar;65(2):263-273
Insulin Treatment Cannot Promote Lipogenesis in Rat Fetal Lung in Gestational Diabetes Mellitus Because of Failure to Redress the Imbalance Among SREBP-1, SCAP, and INSIG-1.
Li J, Qian G, Zhong X, Yu T
DNA and cell biology 2018 Mar;37(3):264-270
DNA and cell biology 2018 Mar;37(3):264-270
Ubenimex, an APN inhibitor, could serve as an anti‑tumor drug in RT112 and 5637 cells by operating in an Akt‑associated manner.
Wang X, Liu Y, Liu W, Zhang Y, Guo F, Zhang L, Cui M, Liu S, Wu R
Molecular medicine reports 2018 Mar;17(3):4531-4539
Molecular medicine reports 2018 Mar;17(3):4531-4539
LIFR increases the release of soluble endoglin via the upregulation of MMP14 expression in preeclampsia.
Li H, Yao J, Chang X, Wu J, Duan T, Wang K
Reproduction (Cambridge, England) 2018 Mar;155(3):297-306
Reproduction (Cambridge, England) 2018 Mar;155(3):297-306
7α,8α-Epoxynagilactones and their glucosides from the twigs of Podocarpus nagi: Isolation, structures, and cytotoxic activities.
Zheng YD, Bai G, Tang C, Ke CQ, Yao S, Tong LJ, Feng F, Li Y, Ding J, Xie H, Ye Y
Fitoterapia 2018 Mar;125:174-183
Fitoterapia 2018 Mar;125:174-183
Nicotine-Induced Neuroprotection against Cognitive Dysfunction after Partial Hepatectomy Involves Activation of BDNF/TrkB Signaling Pathway and Inhibition of NF-κB Signaling Pathway in Aged Rats.
Wei P, Zheng Q, Liu H, Wan T, Zhou J, Li D, Zhou H, Li J, Ji F, Tang W, Li J
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2018 Mar 6;20(4):515-522
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2018 Mar 6;20(4):515-522
Effect of Di-(2-ethylhexyl) phthalate on the hypothalamus-pituitary-thyroid axis in adolescent rat.
Sun D, Zhou L, Wang S, Liu T, Zhu J, Jia Y, Xu J, Chen H, Wang Q, Xu F, Zhang Y, Ye L
Endocrine journal 2018 Mar 28;65(3):261-268
Endocrine journal 2018 Mar 28;65(3):261-268
Exosomes from C2C12 myoblasts enhance osteogenic differentiation of MC3T3-E1 pre-osteoblasts by delivering miR-27a-3p.
Xu Q, Cui Y, Luan J, Zhou X, Li H, Han J
Biochemical and biophysical research communications 2018 Mar 25;498(1):32-37
Biochemical and biophysical research communications 2018 Mar 25;498(1):32-37
New Drug Candidate Targeting the 4A1 Orphan Nuclear Receptor for Medullary Thyroid Cancer Therapy.
Zhang L, Liu W, Wang Q, Li Q, Wang H, Wang J, Teng T, Chen M, Ji A, Li Y
Molecules (Basel, Switzerland) 2018 Mar 2;23(3)
Molecules (Basel, Switzerland) 2018 Mar 2;23(3)
Apoptosome formation upon overexpression of native and truncated Apaf-1 in cell-free and cell-based systems.
Noori AR, Hosseini ES, Nikkhah M, Hosseinkhani S
Archives of biochemistry and biophysics 2018 Mar 15;642:46-51
Archives of biochemistry and biophysics 2018 Mar 15;642:46-51
Mitochondrial Dysfunctions Contribute to Hypertrophic Cardiomyopathy in Patient iPSC-Derived Cardiomyocytes with MT-RNR2 Mutation.
Li S, Pan H, Tan C, Sun Y, Song Y, Zhang X, Yang W, Wang X, Li D, Dai Y, Ma Q, Xu C, Zhu X, Kang L, Fu Y, Xu X, Shu J, Zhou N, Han F, Qin D, Huang W, Liu Z, Yan Q
Stem cell reports 2018 Mar 13;10(3):808-821
Stem cell reports 2018 Mar 13;10(3):808-821
Cell division cycle 7 is a potential therapeutic target in oral squamous cell carcinoma and is regulated by E2F1.
Jin S, Ma H, Yang W, Ju H, Wang L, Zhang Z
Journal of molecular medicine (Berlin, Germany) 2018 Jun;96(6):513-525
Journal of molecular medicine (Berlin, Germany) 2018 Jun;96(6):513-525
IL-6 receptor blockade ameliorates diabetic nephropathy via inhibiting inflammasome in mice.
Wu R, Liu X, Yin J, Wu H, Cai X, Wang N, Qian Y, Wang F
Metabolism: clinical and experimental 2018 Jun;83:18-24
Metabolism: clinical and experimental 2018 Jun;83:18-24
Metformin inhibits ovarian cancer via decreasing H3K27 trimethylation.
Tang G, Guo J, Zhu Y, Huang Z, Liu T, Cai J, Yu L, Wang Z
International journal of oncology 2018 Jun;52(6):1899-1911
International journal of oncology 2018 Jun;52(6):1899-1911
Avian leukosis virus subgroup J promotes cell proliferation and cell cycle progression through miR-221 by targeting CDKN1B.
Ren C, Yu M, Zhang Y, Fan M, Chang F, Xing L, Liu Y, Wang Y, Qi X, Liu C, Zhang Y, Cui H, Li K, Gao L, Pan Q, Wang X, Gao Y
Virology 2018 Jun;519:121-130
Virology 2018 Jun;519:121-130
PEDF improves cardiac function in rats subjected to myocardial ischemia/reperfusion injury by inhibiting ROS generation via PEDF‑R.
Zhao Q, Liu Z, Huang B, Yuan Y, Liu X, Zhang H, Qiu F, Zhang Y, Li Y, Miao H, Dong H, Zhang Z
International journal of molecular medicine 2018 Jun;41(6):3243-3252
International journal of molecular medicine 2018 Jun;41(6):3243-3252
Effect of Banxia Xiexin decoction on Helicobacter pylori-related peptic ulcers and its possible mechanism via the TGF-β/Smad signaling pathway.
Chen S, Huang Y, Wan S, Huang Y, Liang H, Chen S
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2018 Jun;38(3):419-426
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2018 Jun;38(3):419-426
Doxycycline attenuates chronic intermittent hypoxia-induced atrial fibrosis in rats.
Wang W, Zhang K, Li X, Ma Z, Zhang Y, Yuan M, Suo Y, Liang X, Tse G, Goudis CA, Liu T, Li G
Cardiovascular therapeutics 2018 Jun;36(3):e12321
Cardiovascular therapeutics 2018 Jun;36(3):e12321
Cysteine-rich protein 61 regulates adipocyte differentiation from mesenchymal stem cells through mammalian target of rapamycin complex 1 and canonical Wnt signaling.
Yang Y, Qi Q, Wang Y, Shi Y, Yang W, Cen Y, Zhu E, Li X, Chen D, Wang B
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2018 Jun;32(6):3096-3107
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2018 Jun;32(6):3096-3107
A comparison of CRISPR/Cas9 and siRNA-mediated ALDH2 gene silencing in human cell lines.
Wang F, Guo T, Jiang H, Li R, Wang T, Zeng N, Dong G, Zeng X, Li D, Xiao Y, Hu Q, Chen W, Xing X, Wang Q
Molecular genetics and genomics : MGG 2018 Jun;293(3):769-783
Molecular genetics and genomics : MGG 2018 Jun;293(3):769-783
Effects of nicotine on the metabolism and gene expression profile of Sprague‑Dawley rat primary osteoblasts.
Liang D, Wang KJ, Tang ZQ, Liu RH, Zeng F, Cheng MY, Lian QS, Wu HK
Molecular medicine reports 2018 Jun;17(6):8269-8281
Molecular medicine reports 2018 Jun;17(6):8269-8281
Myxovirus resistance protein A inhibits hepatitis C virus replication through JAK-STAT pathway activation.
Wang H, Xin X, Wang M, Han L, Li J, Hao Y, Zheng C, Shen C
Archives of virology 2018 Jun;163(6):1429-1438
Archives of virology 2018 Jun;163(6):1429-1438
Berberine exerts antioxidant effects via protection of spiral ganglion cells against cytomegalovirus-induced apoptosis.
Zhuang W, Li T, Wang C, Shi X, Li Y, Zhang S, Zhao Z, Dong H, Qiao Y
Free radical biology & medicine 2018 Jun;121:127-135
Free radical biology & medicine 2018 Jun;121:127-135
Tert-butylhydroquinone post-treatment attenuates neonatal hypoxic-ischemic brain damage in rats.
Zhang J, Tucker LD, DongYan, Lu Y, Yang L, Wu C, Li Y, Zhang Q
Neurochemistry international 2018 Jun;116:1-12
Neurochemistry international 2018 Jun;116:1-12
Enhancer of zeste homolog 2 promotes cisplatin resistance by reducing cellular platinum accumulation.
Sun S, Zhao S, Yang Q, Wang W, Cai E, Wen Y, Yu L, Wang Z, Cai J
Cancer science 2018 Jun;109(6):1853-1864
Cancer science 2018 Jun;109(6):1853-1864
Effects of Levonorgestrel and progesterone on Oviductal physiology in mammals.
Li C, Zhang HY, Liang Y, Xia W, Zhu Q, Zhang D, Huang Z, Liang GL, Xue RH, Qi H, He XQ, Yuan JJ, Tan YJ, Huang HF, Zhang J
Reproductive biology and endocrinology : RB&E 2018 Jun 20;16(1):59
Reproductive biology and endocrinology : RB&E 2018 Jun 20;16(1):59
Alpha protocadherins and Pyk2 kinase regulate cortical neuron migration and cytoskeletal dynamics via Rac1 GTPase and WAVE complex in mice.
Fan L, Lu Y, Shen X, Shao H, Suo L, Wu Q
eLife 2018 Jun 18;7
eLife 2018 Jun 18;7
DRm217 attenuates myocardial ischemia-reperfusion injury via stabilizing plasma membrane Na+-K+-ATPase, inhibiting Na+-K+-ATPase/ROS pathway and activating PI3K/Akt and ERK1/2.
Yan X, Xun M, Wu L, Du X, Zhang F, Zheng J
Toxicology and applied pharmacology 2018 Jun 15;349:62-71
Toxicology and applied pharmacology 2018 Jun 15;349:62-71
Long noncoding RNA lncARSR promotes hepatic cholesterol biosynthesis via modulating Akt/SREBP-2/HMGCR pathway.
Huang J, Chen S, Cai D, Bian D, Wang F
Life sciences 2018 Jun 15;203:48-53
Life sciences 2018 Jun 15;203:48-53
Acetylation of oxidized base repair-initiating NEIL1 DNA glycosylase required for chromatin-bound repair complex formation in the human genome increases cellular resistance to oxidative stress.
Sengupta S, Yang C, Hegde ML, Hegde PM, Mitra J, Pandey A, Dutta A, Datarwala AT, Bhakat KK, Mitra S
DNA repair 2018 Jun - Jul;66-67:1-10
DNA repair 2018 Jun - Jul;66-67:1-10
Underexpression of Receptor for Activated C Kinase 1 (RACK1) in Leukocytes from Patients with Severe Acute Pancreatitis.
Zhang X, Guo J, Wang H, Zhang C, Shi N, Cai W, Jin T, Lin Z, Ma Y, Yang X, Xia Q, Xue P
The Tohoku journal of experimental medicine 2018 Jul;245(3):205-215
The Tohoku journal of experimental medicine 2018 Jul;245(3):205-215
Generation and propagation of yeast prion [URE3] are elevated under electromagnetic field.
Lian HY, Lin KW, Yang C, Cai P
Cell stress & chaperones 2018 Jul;23(4):581-594
Cell stress & chaperones 2018 Jul;23(4):581-594
Japanese encephalitis virus induces apoptosis by inhibiting Foxo signaling pathway.
Guo F, Yu X, Xu A, Xu J, Wang Q, Guo Y, Wu X, Tang Y, Ding Z, Zhang Y, Gong T, Pan Z, Li S, Kong L
Veterinary microbiology 2018 Jul;220:73-82
Veterinary microbiology 2018 Jul;220:73-82
Membrane topology of rat sodium-coupled neutral amino acid transporter 2 (SNAT2).
Ge Y, Gu Y, Wang J, Zhang Z
Biochimica et biophysica acta. Biomembranes 2018 Jul;1860(7):1460-1469
Biochimica et biophysica acta. Biomembranes 2018 Jul;1860(7):1460-1469
Rapamycin and ZSTK474 can have differential effects at different post‑infection time‑points regarding CVB3 replication and CVB3‑induced autophagy.
Chang H, Tian L, Chen J, Tang A, Li C, Li Z, Yang Z
Molecular medicine reports 2018 Jul;18(1):1088-1094
Molecular medicine reports 2018 Jul;18(1):1088-1094
Chronic stress causes protein kinase C epsilon-aldehyde dehydrogenase 2 signaling pathway perturbation in the rat hippocampus and prefrontal cortex, but not in the myocardium.
Zhang WY, Wang KY, Li YJ, Li YR, Lu RZ
Neural regeneration research 2018 Jul;13(7):1225-1230
Neural regeneration research 2018 Jul;13(7):1225-1230
A Polysaccharide Isolated from Dictyophora indusiata Promotes Recovery from Antibiotic-Driven Intestinal Dysbiosis and Improves Gut Epithelial Barrier Function in a Mouse Model.
Kanwal S, Joseph TP, Owusu L, Xiaomeng R, Meiqi L, Yi X
Nutrients 2018 Jul 31;10(8)
Nutrients 2018 Jul 31;10(8)
The actin cytoskeletal architecture of estrogen receptor positive breast cancer cells suppresses invasion.
Padilla-Rodriguez M, Parker SS, Adams DG, Westerling T, Puleo JI, Watson AW, Hill SM, Noon M, Gaudin R, Aaron J, Tong D, Roe DJ, Knudsen B, Mouneimne G
Nature communications 2018 Jul 30;9(1):2980
Nature communications 2018 Jul 30;9(1):2980
Myc activity is required for maintenance of the neuromesodermal progenitor signalling network and for segmentation clock gene oscillations in mouse.
Mastromina I, Verrier L, Silva JC, Storey KG, Dale JK
Development (Cambridge, England) 2018 Jul 30;145(14)
Development (Cambridge, England) 2018 Jul 30;145(14)
Synthesis and structure-activity relationship studies of MI-2 analogues as MALT1 inhibitors.
Wu G, Wang H, Zhou W, Zeng B, Mo W, Zhu K, Liu R, Zhou J, Chen C, Chen H
Bioorganic & medicinal chemistry 2018 Jul 23;26(12):3321-3344
Bioorganic & medicinal chemistry 2018 Jul 23;26(12):3321-3344
Vitamin C increases 5-hydroxymethylcytosine level and inhibits the growth of bladder cancer.
Peng D, Ge G, Gong Y, Zhan Y, He S, Guan B, Li Y, Xu Z, Hao H, He Z, Xiong G, Zhang C, Shi Y, Zhou Y, Ci W, Li X, Zhou L
Clinical epigenetics 2018 Jul 13;10(1):94
Clinical epigenetics 2018 Jul 13;10(1):94
A novel small-molecule activator of Sirtuin-1 induces autophagic cell death/mitophagy as a potential therapeutic strategy in glioblastoma.
Yao ZQ, Zhang X, Zhen Y, He XY, Zhao S, Li XF, Yang B, Gao F, Guo FY, Fu L, Liu XZ, Duan CZ
Cell death & disease 2018 Jul 10;9(7):767
Cell death & disease 2018 Jul 10;9(7):767
A reproducible swine model of proximal descending thoracic aortic aneurysm created with intra-adventitial application of elastase.
Tian Y, Zhang W, Sun J, Zhai H, Yu Y, Qi X, Jones JA, Zhong H
Journal of vascular surgery 2018 Jan;67(1):300-308.e2
Journal of vascular surgery 2018 Jan;67(1):300-308.e2
Photobiomodulation therapy promotes neurogenesis by improving post-stroke local microenvironment and stimulating neuroprogenitor cells.
Yang L, Tucker D, Dong Y, Wu C, Lu Y, Li Y, Zhang J, Liu TC, Zhang Q
Experimental neurology 2018 Jan;299(Pt A):86-96
Experimental neurology 2018 Jan;299(Pt A):86-96
Hypoxia induces the dysfunction of human endothelial colony-forming cells via HIF-1α signaling.
He M, Ma S, Cai Q, Wu Y, Shao C, Kong H, Wang H, Zeng X, Xie W
Respiratory physiology & neurobiology 2018 Jan;247:87-95
Respiratory physiology & neurobiology 2018 Jan;247:87-95
Mechanism of prolactin inhibition of miR-135b via methylation in goat mammary epithelial cells.
Chen Z, Luo J, Zhang C, Ma Y, Sun S, Zhang T, Loor JJ
Journal of cellular physiology 2018 Jan;233(1):651-662
Journal of cellular physiology 2018 Jan;233(1):651-662
Selectivity, cell permeability and oral availability studies of novel bromophenol derivative HPN as protein tyrosine phosphatase 1B inhibitor.
Luo J, Xu Q, Jiang B, Zhang R, Jia X, Li X, Wang L, Guo C, Wu N, Shi D
British journal of pharmacology 2018 Jan;175(1):140-153
British journal of pharmacology 2018 Jan;175(1):140-153
Clinical efficacy of recombinant human latrophilin 3 antibody in the treatment of pediatric asthma.
Liu M, Zhang J, Liu C
Experimental and therapeutic medicine 2018 Jan;15(1):539-547
Experimental and therapeutic medicine 2018 Jan;15(1):539-547
PTEN-L promotes type I interferon responses and antiviral immunity.
Cao Y, Wang H, Yang L, Zhang Z, Li C, Yuan X, Bu L, Chen L, Chen Y, Li CM, Guo D
Cellular & molecular immunology 2018 Jan;15(1):48-57
Cellular & molecular immunology 2018 Jan;15(1):48-57
Epithelial-mesenchymal crosstalk induces radioresistance in HNSCC cells.
Steinbichler TB, Alshaimaa A, Maria MV, Daniel D, Herbert R, Jozsef D, Ira-Ida S
Oncotarget 2018 Jan 9;9(3):3641-3652
Oncotarget 2018 Jan 9;9(3):3641-3652
Wnt/β-catenin pathway promotes acute lung injury induced by LPS through driving the Th17 response in mice.
Cheng L, Zhao Y, Qi D, Li W, Wang D
Biochemical and biophysical research communications 2018 Jan 8;495(2):1890-1895
Biochemical and biophysical research communications 2018 Jan 8;495(2):1890-1895
Comparative Proteomics Analysis Identifies Cdc42-Cdc42BPA Signaling as Prognostic Biomarker and Therapeutic Target for Colon Cancer Invasion.
Hu HF, Xu WW, Wang Y, Zheng CC, Zhang WX, Li B, He QY
Journal of proteome research 2018 Jan 5;17(1):265-275
Journal of proteome research 2018 Jan 5;17(1):265-275
Rhubarb Supplementation Promotes Intestinal Mucosal Innate Immune Homeostasis through Modulating Intestinal Epithelial Microbiota in Goat Kids.
Jiao J, Wu J, Wang M, Zhou C, Zhong R, Tan Z
Journal of agricultural and food chemistry 2018 Jan 31;66(4):1047-1057
Journal of agricultural and food chemistry 2018 Jan 31;66(4):1047-1057
Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral β-lactam bridged combretastatin A-4 analogues as potent antitumor agents.
Zhou P, Liang Y, Zhang H, Jiang H, Feng K, Xu P, Wang J, Wang X, Ding K, Luo C, Liu M, Wang Y
European journal of medicinal chemistry 2018 Jan 20;144:817-842
European journal of medicinal chemistry 2018 Jan 20;144:817-842
SOCE induced calcium overload regulates autophagy in acute pancreatitis via calcineurin activation.
Zhu ZD, Yu T, Liu HJ, Jin J, He J
Cell death & disease 2018 Jan 19;9(2):50
Cell death & disease 2018 Jan 19;9(2):50
Autophagy promotes metastasis and glycolysis by upregulating MCT1 expression and Wnt/β-catenin signaling pathway activation in hepatocellular carcinoma cells.
Fan Q, Yang L, Zhang X, Ma Y, Li Y, Dong L, Zong Z, Hua X, Su D, Li H, Liu J
Journal of experimental & clinical cancer research : CR 2018 Jan 19;37(1):9
Journal of experimental & clinical cancer research : CR 2018 Jan 19;37(1):9
Proteasome Inhibitor Carbobenzoxy-L-Leucyl-L-Leucyl-L-Leucinal (MG132) Enhances Therapeutic Effect of Paclitaxel on Breast Cancer by Inhibiting Nuclear Factor (NF)-κB Signaling.
Zhang Y, Yang B, Zhao J, Li X, Zhang L, Zhai Z
Medical science monitor : international medical journal of experimental and clinical research 2018 Jan 15;24:294-304
Medical science monitor : international medical journal of experimental and clinical research 2018 Jan 15;24:294-304
miR-3189-3p Mimics Enhance the Effects of S100A4 siRNA on the Inhibition of Proliferation and Migration of Gastric Cancer Cells by Targeting CFL2.
Bian Y, Guo J, Qiao L, Sun X
International journal of molecular sciences 2018 Jan 13;19(1)
International journal of molecular sciences 2018 Jan 13;19(1)
Uncovering the anticancer mechanism of Compound Kushen Injection against HCC by integrating quantitative analysis, network analysis and experimental validation.
Gao L, Wang KX, Zhou YZ, Fang JS, Qin XM, Du GH
Scientific reports 2018 Jan 12;8(1):624
Scientific reports 2018 Jan 12;8(1):624
Dietary Supplement of Large Yellow Tea Ameliorates Metabolic Syndrome and Attenuates Hepatic Steatosis in db/db Mice.
Teng Y, Li D, Guruvaiah P, Xu N, Xie Z
Nutrients 2018 Jan 12;10(1)
Nutrients 2018 Jan 12;10(1)
Repulsive guidance molecule a suppresses angiogenesis after ischemia/reperfusion injury of middle cerebral artery occlusion in rats.
Wang Y, Zhang R, Xing X, Guo J, Xie F, Zhang G, Qin X
Neuroscience letters 2018 Jan 1;662:318-323
Neuroscience letters 2018 Jan 1;662:318-323
Protein Kinase A/CREB Signaling Prevents Adriamycin-Induced Podocyte Apoptosis via Upregulation of Mitochondrial Respiratory Chain Complexes.
Xie K, Zhu M, Xiang P, Chen X, Kasimumali A, Lu R, Wang Q, Mou S, Ni Z, Gu L, Pang H
Molecular and cellular biology 2018 Jan 1;38(1)
Molecular and cellular biology 2018 Jan 1;38(1)
Eukaryotic translation initiation factor 2 subunit α (eIF2α) inhibitor salubrinal attenuates paraquat-induced human lung epithelial-like A549 cell apoptosis by regulating the PERK-eIF2α signaling pathway.
Wang R, Sun DZ, Song CQ, Xu YM, Liu W, Liu Z, Dong XS
Toxicology in vitro : an international journal published in association with BIBRA 2018 Feb;46:58-65
Toxicology in vitro : an international journal published in association with BIBRA 2018 Feb;46:58-65
RhPDCD5 combined with dexamethasone increases antitumor activity in multiple myeloma partially via inhibiting the Wnt signalling pathway.
Cheng Q, Liu L, Fu Y, Zhang Y, Yang Y, Liu J
Clinical and experimental pharmacology & physiology 2018 Feb;45(2):140-145
Clinical and experimental pharmacology & physiology 2018 Feb;45(2):140-145
Aberrant expression of miR-451a contributes to 1,2-dichloroethane-induced hepatic glycerol gluconeogenesis disorder by inhibiting glycerol kinase expression in NIH Swiss mice.
Zeng N, Jiang H, Fan Q, Wang T, Rong W, Li G, Li R, Xu D, Guo T, Wang F, Zeng L, Huang M, Zheng J, Lu F, Chen W, Hu Q, Huang Z, Wang Q
Journal of applied toxicology : JAT 2018 Feb;38(2):292-303
Journal of applied toxicology : JAT 2018 Feb;38(2):292-303
Ephrin receptor A2 is an epithelial cell receptor for Epstein-Barr virus entry.
Zhang H, Li Y, Wang HB, Zhang A, Chen ML, Fang ZX, Dong XD, Li SB, Du Y, Xiong D, He JY, Li MZ, Liu YM, Zhou AJ, Zhong Q, Zeng YX, Kieff E, Zhang Z, Gewurz BE, Zhao B, Zeng MS
Nature microbiology 2018 Feb;3(2):1-8
Nature microbiology 2018 Feb;3(2):1-8
Carnosol-mediated Sirtuin 1 activation inhibits Enhancer of Zeste Homolog 2 to attenuate liver fibrosis.
Zhao H, Wang Z, Tang F, Zhao Y, Feng D, Li Y, Hu Y, Wang C, Zhou J, Tian X, Yao J
Pharmacological research 2018 Feb;128:327-337
Pharmacological research 2018 Feb;128:327-337
N-oleoylethanolamide suppresses intimal hyperplasia after balloon injury in rats through AMPK/PPARα pathway.
Zhao Y, Liu Y, Jing Z, Peng L, Jin P, Lin Y, Zhou Y, Yang L, Ren J, Xie Q, Jin X
Biochemical and biophysical research communications 2018 Feb 5;496(2):415-421
Biochemical and biophysical research communications 2018 Feb 5;496(2):415-421
PUM1 promotes ovarian cancer proliferation, migration and invasion.
Guan X, Chen S, Liu Y, Wang LL, Zhao Y, Zong ZH
Biochemical and biophysical research communications 2018 Feb 26;497(1):313-318
Biochemical and biophysical research communications 2018 Feb 26;497(1):313-318
Interferon-alpha enhances the antitumour activity of EGFR-targeted therapies by upregulating RIG-I in head and neck squamous cell carcinoma.
Ma H, Jin S, Yang W, Zhou G, Zhao M, Fang S, Zhang Z, Hu J
British journal of cancer 2018 Feb 20;118(4):509-521
British journal of cancer 2018 Feb 20;118(4):509-521
Involvement of impaired autophagy and mitophagy in Neuro-2a cell damage under hypoxic and/or high-glucose conditions.
Song Y, Du Y, Zou W, Luo Y, Zhang X, Fu J
Scientific reports 2018 Feb 19;8(1):3301
Scientific reports 2018 Feb 19;8(1):3301
Hypoxia Activates Src and Promotes Endocytosis Which Decreases MMP-2 Activity and Aggravates Renal Interstitial Fibrosis.
Cheng Z, Liu L, Wang Z, Cai Y, Xu Q, Chen P
International journal of molecular sciences 2018 Feb 15;19(2)
International journal of molecular sciences 2018 Feb 15;19(2)
The RARS-MAD1L1 Fusion Gene Induces Cancer Stem Cell-like Properties and Therapeutic Resistance in Nasopharyngeal Carcinoma.
Zhong Q, Liu ZH, Lin ZR, Hu ZD, Yuan L, Liu YM, Zhou AJ, Xu LH, Hu LJ, Wang ZF, Guan XY, Hao JJ, Lui VWY, Guo L, Mai HQ, Chen MY, Han F, Xia YF, Grandis JR, Zhang X, Zeng MS
Clinical cancer research : an official journal of the American Association for Cancer Research 2018 Feb 1;24(3):659-673
Clinical cancer research : an official journal of the American Association for Cancer Research 2018 Feb 1;24(3):659-673
Effects of garlic polysaccharide on alcoholic liver fibrosis and intestinal microflora in mice.
Wang Y, Guan M, Zhao X, Li X
Pharmaceutical biology 2018 Dec;56(1):325-332
Pharmaceutical biology 2018 Dec;56(1):325-332
Involvement of PINK1/Parkin-mediated mitophagy in paraquat- induced apoptosis in human lung epithelial-like A549 cells.
Sun DZ, Song CQ, Xu YM, Wang R, Liu W, Liu Z, Dong XS
Toxicology in vitro : an international journal published in association with BIBRA 2018 Dec;53:148-159
Toxicology in vitro : an international journal published in association with BIBRA 2018 Dec;53:148-159
Oxymatrine attenuates brain hypoxic-ischemic injury from apoptosis and oxidative stress: role of p-Akt/GSK3β/HO-1/Nrf-2 signaling pathway.
Ge XH, Shao L, Zhu GJ
Metabolic brain disease 2018 Dec;33(6):1869-1875
Metabolic brain disease 2018 Dec;33(6):1869-1875
RNF126 Quenches RNF168 Function in the DNA Damage Response.
Zhang L, Wang Z, Shi R, Zhu X, Zhou J, Peng B, Xu X
Genomics, proteomics & bioinformatics 2018 Dec;16(6):428-438
Genomics, proteomics & bioinformatics 2018 Dec;16(6):428-438
1,3-Dichloro-2-Propanol inhibits autophagy via P53/AMPK/mTOR pathway in HepG2 cells.
Cheng B, Lu J, Li T, Meng Z, Liu M, Sun M, Guan S
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2018 Dec;122:143-150
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2018 Dec;122:143-150
Urea transport B gene induces melanoma B16 cell death via activation of p53 and mitochondrial apoptosis.
Liu L, Sun Y, Zhao Y, Wang Q, Guo H, Guo R, Liu Y, Fu S, Zhang L, Li Y, Meng Y
Cancer science 2018 Dec;109(12):3762-3773
Cancer science 2018 Dec;109(12):3762-3773
Type 3 innate lymphoid cell: a new player in liver fibrosis progression.
Wang S, Li J, Wu S, Cheng L, Shen Y, Ma W, She W, Yang C, Wang J, Jiang W
Clinical science (London, England : 1979) 2018 Dec 21;132(24):2565-2582
Clinical science (London, England : 1979) 2018 Dec 21;132(24):2565-2582
Long non-coding RNA BRE-AS1 represses non-small cell lung cancer cell growth and survival via up-regulating NR4A3.
Zhang M, Wu J, Zhong W, Zhao Z, Liu Z
Archives of biochemistry and biophysics 2018 Dec 15;660:53-63
Archives of biochemistry and biophysics 2018 Dec 15;660:53-63
Protein A from orange-spotted grouper nervous necrosis virus triggers type I interferon production in fish cell.
Huang R, Zhou Q, Shi Y, Zhang J, He J, Xie J
Fish & shellfish immunology 2018 Aug;79:234-243
Fish & shellfish immunology 2018 Aug;79:234-243
Overcoming resistance to mitochondrial apoptosis by BZML-induced mitotic catastrophe is enhanced by inhibition of autophagy in A549/Taxol cells.
Bai Z, Gao M, Xu X, Zhang H, Xu J, Guan Q, Wang Q, Du J, Li Z, Zuo D, Zhang W, Wu Y
Cell proliferation 2018 Aug;51(4):e12450
Cell proliferation 2018 Aug;51(4):e12450
Osteoglycin-induced VEGF Inhibition Enhances T Lymphocytes Infiltrating in Colorectal Cancer.
Hu X, Li YQ, Li QG, Ma YL, Peng JJ, Cai SJ
EBioMedicine 2018 Aug;34:35-45
EBioMedicine 2018 Aug;34:35-45
Restoration of 5-hydroxymethylcytosine by ascorbate blocks kidney tumour growth.
Ge G, Peng D, Xu Z, Guan B, Xin Z, He Q, Zhou Y, Li X, Zhou L, Ci W
EMBO reports 2018 Aug;19(8)
EMBO reports 2018 Aug;19(8)
Matrine inhibits the proliferation and migration of lung cancer cells through regulation of the protein kinase B/glycogen synthase kinase-3β signaling pathways.
Xie W, Lu J, Lu Q, Wang X, Long H, Huang J, Guo Z
Experimental and therapeutic medicine 2018 Aug;16(2):723-729
Experimental and therapeutic medicine 2018 Aug;16(2):723-729
TNFSF14/LIGHT, a Non-Canonical NF-κB Stimulus, Induces the HIF Pathway.
D'Ignazio L, Batie M, Rocha S
Cells 2018 Aug 8;7(8)
Cells 2018 Aug 8;7(8)
NRAGE confers poor prognosis and promotes proliferation, invasion, and chemoresistance in gastric cancer.
Jiang X, Jiang X, Yang Z
Gene 2018 Aug 20;668:114-120
Gene 2018 Aug 20;668:114-120
Selenium-enriched yeast inhibited β-amyloid production and modulated autophagy in a triple transgenic mouse model of Alzheimer's disease.
Song GL, Chen C, Wu QY, Zhang ZH, Zheng R, Chen Y, Jia SZ, Ni JZ
Metallomics : integrated biometal science 2018 Aug 15;10(8):1107-1115
Metallomics : integrated biometal science 2018 Aug 15;10(8):1107-1115
Effects of Dahuang zhechong pill on doxorubicin-resistant SMMC-7721 xenografts in mice.
Wu L, Cao KX, Ni ZH, Li WD, Chen ZP, Cheng HB, Liu X
Journal of ethnopharmacology 2018 Aug 10;222:71-78
Journal of ethnopharmacology 2018 Aug 10;222:71-78
Uncoupling protein 1 expression in adipocytes derived from skeletal muscle fibro/adipogenic progenitors is under genetic and hormonal control.
Gorski T, Mathes S, Krützfeldt J
Journal of cachexia, sarcopenia and muscle 2018 Apr;9(2):384-399
Journal of cachexia, sarcopenia and muscle 2018 Apr;9(2):384-399
Role of TGF-β activated kinase-1 inhibitor on the interaction between macrophages and mesangial cells on the condition of high glucose.
Fan Z, Xu X, Qi X, Wu Y
Immunological investigations 2018 Apr;47(3):303-314
Immunological investigations 2018 Apr;47(3):303-314
MiR-151a is involved in the pathogenesis of atopic dermatitis by regulating interleukin-12 receptor β2.
Chen XF, Zhang LJ, Zhang J, Dou X, Shao Y, Jia XJ, Zhang W, Yu B
Experimental dermatology 2018 Apr;27(4):427-432
Experimental dermatology 2018 Apr;27(4):427-432
TIPE2 is negatively correlated with tissue factor and thrombospondin-1 expression in patients with bronchial asthma.
Shi G, Zhao JW, Sun XX, Ma JF, Wang P, He FC, Ming L
Experimental and therapeutic medicine 2018 Apr;15(4):3449-3454
Experimental and therapeutic medicine 2018 Apr;15(4):3449-3454
The enhancement of siPLK1 penetration across BBB and its anti glioblastoma activity in vivo by magnet and transferrin co-modified nanoparticle.
Liu DZ, Cheng Y, Cai RQ, Wang Bd WW, Cui H, Liu M, Zhang BL, Mei QB, Zhou SY
Nanomedicine : nanotechnology, biology, and medicine 2018 Apr;14(3):991-1003
Nanomedicine : nanotechnology, biology, and medicine 2018 Apr;14(3):991-1003
Identification of novel Nrf2 activators from Cinnamomum chartophyllum H.W. Li and their potential application of preventing oxidative insults in human lung epithelial cells.
Zhou MX, Li GH, Sun B, Xu YW, Li AL, Li YR, Ren DM, Wang XN, Wen XS, Lou HX, Shen T
Redox biology 2018 Apr;14:154-163
Redox biology 2018 Apr;14:154-163
Catalpol ameliorates hepatic insulin resistance in type 2 diabetes through acting on AMPK/NOX4/PI3K/AKT pathway.
Yan J, Wang C, Jin Y, Meng Q, Liu Q, Liu Z, Liu K, Sun H
Pharmacological research 2018 Apr;130:466-480
Pharmacological research 2018 Apr;130:466-480
Protective effect of methylallyl sulfone in the development of cigarette smoke extract-induced apoptosis in rats and HFL-1 cells.
Li A, Liu Y, Zhu X, Sun X, Feng X, Li D, Zhang J, Zhu M, Zhao Z
Biochemical and biophysical research communications 2018 Apr 6;498(3):627-632
Biochemical and biophysical research communications 2018 Apr 6;498(3):627-632
Smurf1 restricts the antiviral function mediated by USP25 through promoting its ubiquitination and degradation.
Qian G, Hu X, Li G, Ding Y, Zhu L, Zheng H, Li M, Li Z, Pan J, Li Y, Li G, Yang C, Liu Y, Xie Y, Lv H
Biochemical and biophysical research communications 2018 Apr 6;498(3):537-543
Biochemical and biophysical research communications 2018 Apr 6;498(3):537-543
GRASP55 Senses Glucose Deprivation through O-GlcNAcylation to Promote Autophagosome-Lysosome Fusion.
Zhang X, Wang L, Lak B, Li J, Jokitalo E, Wang Y
Developmental cell 2018 Apr 23;45(2):245-261.e6
Developmental cell 2018 Apr 23;45(2):245-261.e6
Role of silent information regulator 1 in the protective effect of hydrogen sulfide on homocysteine-induced cognitive dysfunction: Involving reduction of hippocampal ER stress.
Tang YY, Wang AP, Wei HJ, Li MH, Zou W, Li X, Wang CY, Zhang P, Tang XQ
Behavioural brain research 2018 Apr 16;342:35-42
Behavioural brain research 2018 Apr 16;342:35-42
Nogo-B receptor promotes epithelial-mesenchymal transition in non-small cell lung cancer cells through the Ras/ERK/Snail1 pathway.
Wu D, Zhao B, Qi X, Peng F, Fu H, Chi X, Miao QR, Shao S
Cancer letters 2018 Apr 1;418:135-146
Cancer letters 2018 Apr 1;418:135-146
GRHL2 suppresses tumor metastasis via regulation of transcriptional activity of RhoG in non-small cell lung cancer.
Pan X, Zhang R, Xie C, Gan M, Yao S, Yao Y, Jin J, Han T, Huang Y, Gong Y, Wang J, Yu B
American journal of translational research 2017;9(9):4217-4226
American journal of translational research 2017;9(9):4217-4226
Silencing Rab14 represses the proliferation and migration of oral squamous cell carcinoma, and enhances cisplatin sensitivity.
Lian Q, Ma DM, Chen MG, Chen K, Li XJ
American journal of translational research 2017;9(9):4195-4205
American journal of translational research 2017;9(9):4195-4205
3-Mercaptopyruvate Sulfurtransferase, Not Cystathionine β-Synthase Nor Cystathionine γ-Lyase, Mediates Hypoxia-Induced Migration of Vascular Endothelial Cells.
Tao B, Wang R, Sun C, Zhu Y
Frontiers in pharmacology 2017;8:657
Frontiers in pharmacology 2017;8:657
Antimycobacterial and Anti-inflammatory Mechanisms of Baicalin via Induced Autophagy in Macrophages Infected with Mycobacterium tuberculosis.
Zhang Q, Sun J, Wang Y, He W, Wang L, Zheng Y, Wu J, Zhang Y, Jiang X
Frontiers in microbiology 2017;8:2142
Frontiers in microbiology 2017;8:2142
Variant Amino Acid Residues Alter the Enzyme Activity of Peanut Type 2 Diacylglycerol Acyltransferases.
Zheng L, Shockey J, Bian F, Chen G, Shan L, Li X, Wan S, Peng Z
Frontiers in plant science 2017;8:1751
Frontiers in plant science 2017;8:1751
Iridoids with Genipin Stem Nucleus Inhibit Lipopolysaccharide-Induced Inflammation and Oxidative Stress by Blocking the NF-κB Pathway in Polycystic Ovary Syndrome.
Zuo T, Zhu M, Xu W, Wang Z, Song H
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(5):1855-1865
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(5):1855-1865
The USP7 Inhibitor P5091 Induces Cell Death in Ovarian Cancers with Different P53 Status.
Wang M, Zhang Y, Wang T, Zhang J, Zhou Z, Sun Y, Wang S, Shi Y, Luan X, Zhang Y, Wang Y, Wang Y, Zou Z, Kang L, Liu H
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(5):1755-1766
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(5):1755-1766
α-Lipoic Acid Promotes Neurological Recovery After Ischemic Stroke by Activating the Nrf2/HO-1 Pathway to Attenuate Oxidative Damage.
Lv C, Maharjan S, Wang Q, Sun Y, Han X, Wang S, Mao Z, Xin Y, Zhang B
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(3):1273-1287
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(3):1273-1287
Targeted kinase inhibition relieves slowness and tremor in a Drosophila model of LRRK2 Parkinson's disease.
Cording AC, Shiaelis N, Petridi S, Middleton CA, Wilson LG, Elliott CJH
NPJ Parkinson's disease 2017;3:34
NPJ Parkinson's disease 2017;3:34
Endoplasmic Reticulum Stress Is Involved in Cochlear Cell Apoptosis in a Cisplatin-Induced Ototoxicity Rat Model.
Zong S, Liu T, Wan F, Chen P, Luo P, Xiao H
Audiology & neuro-otology 2017;22(3):160-168
Audiology & neuro-otology 2017;22(3):160-168
Role of Zebrafish fhl1A in Satellite Cell and Skeletal Muscle Development.
Chen F, Yuan W, Mo X, Zhuang J, Wang Y, Chen J, Jiang Z, Zhu X, Zeng Q, Wan Y, Li F, Shi Y, Cao L, Fan X, Luo S, Ye X, Chen Y, Dai G, Gao J, Wang X, Xie H, Zhu P, Li Y, Wu X
Current molecular medicine 2017;17(9):627-636
Current molecular medicine 2017;17(9):627-636
XRCC5 cooperates with p300 to promote cyclooxygenase-2 expression and tumor growth in colon cancers.
Zhang Z, Zheng F, Yu Z, Hao J, Chen M, Yu W, Guo W, Chen Y, Huang W, Duan Z, Deng W
PloS one 2017;12(10):e0186900
PloS one 2017;12(10):e0186900
miR-125b-5p functions as a tumor suppressor gene partially by regulating HMGA2 in esophageal squamous cell carcinoma.
Mei LL, Wang WJ, Qiu YT, Xie XF, Bai J, Shi ZZ
PloS one 2017;12(10):e0185636
PloS one 2017;12(10):e0185636
Autophagy promotes degradation of polyethyleneimine-alginate nanoparticles in endothelial progenitor cells.
Wang GD, Tan YZ, Wang HJ, Zhou P
International journal of nanomedicine 2017;12:6661-6675
International journal of nanomedicine 2017;12:6661-6675
Curcumin Activates AMPK Pathway and Regulates Lipid Metabolism in Rats Following Prolonged Clozapine Exposure.
Liu Z, Cui C, Xu P, Dang R, Cai H, Liao D, Yang M, Feng Q, Yan X, Jiang P
Frontiers in neuroscience 2017;11:558
Frontiers in neuroscience 2017;11:558
Paeoniflorin attenuates incipient diabetic nephropathy in streptozotocin-induced mice by the suppression of the Toll-like receptor-2 signaling pathway.
Shao YX, Xu XX, Wang K, Qi XM, Wu YG
Drug design, development and therapy 2017;11:3221-3233
Drug design, development and therapy 2017;11:3221-3233
Roux-en-Y Gastric Bypass Improves Hepatic Glucose Metabolism Involving Down-Regulation of Protein Tyrosine Phosphatase 1B in Obese Rats.
Mu S, Liu J, Guo W, Zhang S, Xiao X, Wang Z, Zhang J
Obesity facts 2017;10(3):191-206
Obesity facts 2017;10(3):191-206
HOXD-AS1 functions as an oncogenic ceRNA to promote NSCLC cell progression by sequestering miR-147a.
Wang Q, Jiang S, Song A, Hou S, Wu Q, Qi L, Gao X
OncoTargets and therapy 2017;10:4753-4763
OncoTargets and therapy 2017;10:4753-4763
Transcription Factor NFAT5 Promotes Glioblastoma Cell-driven Angiogenesis via SBF2-AS1/miR-338-3p-Mediated EGFL7 Expression Change.
Yu H, Zheng J, Liu X, Xue Y, Shen S, Zhao L, Li Z, Liu Y
Frontiers in molecular neuroscience 2017;10:301
Frontiers in molecular neuroscience 2017;10:301
Identification of Flavin-Containing Monooxygenase 5 (FMO5) as a Regulator of Glucose Homeostasis and a Potential Sensor of Gut Bacteria.
Scott F, Gonzalez Malagon SG, O'Brien BA, Fennema D, Veeravalli S, Coveney CR, Phillips IR, Shephard EA
Drug metabolism and disposition: the biological fate of chemicals 2017 Sep;45(9):982-989
Drug metabolism and disposition: the biological fate of chemicals 2017 Sep;45(9):982-989
Visfatin induces the apoptosis of endothelial progenitor cells via the induction of pro-inflammatory mediators through the NF-κB pathway.
Sun L, Chen S, Gao H, Ren L, Song G
International journal of molecular medicine 2017 Sep;40(3):637-646
International journal of molecular medicine 2017 Sep;40(3):637-646
Mechanism of Lycium barbarum polysaccharides on primary cultured rat hippocampal neurons.
Zhao P, Ma NT, Chang RY, Li YX, Hao YJ, Yang WL, Zheng J, Niu Y, Sun T, Yu JQ
Cell and tissue research 2017 Sep;369(3):455-465
Cell and tissue research 2017 Sep;369(3):455-465
Downregulation of serum RAB27B confers improved prognosis and is associated with hepatocellular carcinoma progression through PI3K-AKT-P21 signaling.
Yang X, Ye X, Sun L, Gao F, Li Y, Ji X, Wang X, Feng Y, Wang X
Oncotarget 2017 Sep 22;8(37):61118-61132
Oncotarget 2017 Sep 22;8(37):61118-61132
Dendrobium nobile Lindl. alkaloids regulate metabolism gene expression in livers of mice.
Xu YY, Xu YS, Wang Y, Wu Q, Lu YF, Liu J, Shi JS
The Journal of pharmacy and pharmacology 2017 Oct;69(10):1409-1417
The Journal of pharmacy and pharmacology 2017 Oct;69(10):1409-1417
APPL1 promotes the migration of gastric cancer cells by regulating Akt2 phosphorylation.
Liu Y, Zhang C, Zhao L, Du N, Hou N, Song T, Huang C
International journal of oncology 2017 Oct;51(4):1343-1351
International journal of oncology 2017 Oct;51(4):1343-1351
Thrombospondin-1 Production Regulates the Inflammatory Cytokine Secretion in THP-1 Cells Through NF-κB Signaling Pathway.
Xing T, Wang Y, Ding WJ, Li YL, Hu XD, Wang C, Ding A, Shen JL
Inflammation 2017 Oct;40(5):1606-1621
Inflammation 2017 Oct;40(5):1606-1621
An Important Function of Petrosiol E in Inducing the Differentiation of Neuronal Progenitors and in Protecting Them against Oxidative Stress.
Liu J, Wang L, Du Y, Liu S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2017 Oct;4(10):1700089
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2017 Oct;4(10):1700089
Anti-inflammatory capacity of Lactobacillus rhamnosus GG in monophasic variant Salmonella infected piglets is correlated with impeding NLRP6-mediated host inflammatory responses.
Yu J, Zhu YH, Yang GY, Zhang W, Zhou D, Su JH, Wang JF
Veterinary microbiology 2017 Oct;210:91-100
Veterinary microbiology 2017 Oct;210:91-100
Ovarian cancer proliferation and apoptosis are regulated by human transfer RNA methyltransferase 9-likevia LIN9.
Chen HM, Wang J, Zhang YF, Gao YH
Oncology letters 2017 Oct;14(4):4461-4466
Oncology letters 2017 Oct;14(4):4461-4466
The role of long non-coding RNA PCA3 in epithelial ovarian carcinoma tumorigenesis and progression.
Liu Y, Zong ZH, Guan X, Wang LL, Zhao Y
Gene 2017 Oct 30;633:42-47
Gene 2017 Oct 30;633:42-47
Inhibition of Starvation-Triggered Endoplasmic Reticulum Stress, Autophagy, and Apoptosis in ARPE-19 Cells by Taurine through Modulating the Expression of Calpain-1 and Calpain-2.
Zhang Y, Ren S, Liu Y, Gao K, Liu Z, Zhang Z
International journal of molecular sciences 2017 Oct 14;18(10)
International journal of molecular sciences 2017 Oct 14;18(10)
Evidence for a direct cross-talk between malic enzyme and the pentose phosphate pathway via structural interactions.
Yao P, Sun H, Xu C, Chen T, Zou B, Jiang P, Du W
The Journal of biological chemistry 2017 Oct 13;292(41):17113-17120
The Journal of biological chemistry 2017 Oct 13;292(41):17113-17120
Ligand-dependent EphA7 signaling inhibits prostate tumor growth and progression.
Li S, Wu Z, Ma P, Xu Y, Chen Y, Wang H, He P, Kang Z, Yin L, Zhao Y, Zhang X, Xu X, Ma X, Guan M
Cell death & disease 2017 Oct 12;8(10):e3122
Cell death & disease 2017 Oct 12;8(10):e3122
Fluoride-Induced Autophagy via the Regulation of Phosphorylation of Mammalian Targets of Rapamycin in Mice Leydig Cells.
Zhang J, Zhu Y, Shi Y, Han Y, Liang C, Feng Z, Zheng H, Eng M, Wang J
Journal of agricultural and food chemistry 2017 Oct 11;65(40):8966-8976
Journal of agricultural and food chemistry 2017 Oct 11;65(40):8966-8976
MicroRNA-23a promotes pancreatic cancer metastasis by targeting epithelial splicing regulator protein 1.
Wu G, Li Z, Jiang P, Zhang X, Xu Y, Chen K, Li X
Oncotarget 2017 Oct 10;8(47):82854-82871
Oncotarget 2017 Oct 10;8(47):82854-82871
Epigenetic silencing of ASPP1 confers 5-FU resistance in clear cell renal cell carcinoma by preventing p53 activation.
Wang X, Cheng Y, Zhu Y, Li H, Ge W, Wu X, Zhao K, Yuan J, Li Z, Jiang S, Han Z, Jiang Q, Wu Q, Liu T, Zhang C, Yu M, Hu Y
International journal of cancer 2017 Oct 1;141(7):1422-1433
International journal of cancer 2017 Oct 1;141(7):1422-1433
Cryptotanshinone sensitizes antitumor effect of paclitaxel on tongue squamous cell carcinoma growth by inhibiting the JAK/STAT3 signaling pathway.
Wang Y, Lu HL, Liu YD, Yang LY, Jiang QK, Zhu XJ, Fan HN, Qian Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Nov;95:1388-1396
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Nov;95:1388-1396
Spatiotemporal Expression of Bcl-2/Bax and Neural Cell Apoptosis in the Developing Lumbosacral Spinal Cord of Rat Fetuses with Anorectal Malformations.
Yang Z, Geng Y, Yao Z, Jia H, Bai Y, Wang W
Neurochemical research 2017 Nov;42(11):3160-3169
Neurochemical research 2017 Nov;42(11):3160-3169
Sialic acid-modified solid lipid nanoparticles as vascular endothelium-targeting carriers for ischemia-reperfusion-induced acute renal injury.
Hu JB, Song GL, Liu D, Li SJ, Wu JH, Kang XQ, Qi J, Jin FY, Wang XJ, Xu XL, Ying XY, Yu L, You J, Du YZ
Drug delivery 2017 Nov;24(1):1856-1867
Drug delivery 2017 Nov;24(1):1856-1867
Lack of BACE1 S-palmitoylation reduces amyloid burden and mitigates memory deficits in transgenic mouse models of Alzheimer's disease.
Andrew RJ, Fernandez CG, Stanley M, Jiang H, Nguyen P, Rice RC, Buggia-Prévot V, De Rossi P, Vetrivel KS, Lamb R, Argemi A, Allaert ES, Rathbun EM, Krause SV, Wagner SL, Parent AT, Holtzman DM, Thinakaran G
Proceedings of the National Academy of Sciences of the United States of America 2017 Nov 7;114(45):E9665-E9674
Proceedings of the National Academy of Sciences of the United States of America 2017 Nov 7;114(45):E9665-E9674
Cell-autonomous adiposity through increased cell surface GLUT4 due to ankyrin-B deficiency.
Lorenzo DN, Bennett V
Proceedings of the National Academy of Sciences of the United States of America 2017 Nov 28;114(48):12743-12748
Proceedings of the National Academy of Sciences of the United States of America 2017 Nov 28;114(48):12743-12748
Proteomics and metabolomics analysis of hepatic mitochondrial metabolism in alcohol-preferring and non-preferring rats.
Zeng HL, Yang Q, Du H, Li H, Shen Y, Liu T, Chen X, Kamal GM, Guan Q, Cheng L, Wang J, Xu F
Oncotarget 2017 Nov 24;8(60):102020-102032
Oncotarget 2017 Nov 24;8(60):102020-102032
Copper or/and arsenic induce oxidative stress-cascaded, nuclear factor kappa B-dependent inflammation and immune imbalance, trigging heat shock response in the kidney of chicken.
Wang Y, Zhao H, Shao Y, Liu J, Li J, Xing M
Oncotarget 2017 Nov 17;8(58):98103-98116
Oncotarget 2017 Nov 17;8(58):98103-98116
Hydrogen Sulfide Inhibits Chronic Unpredictable Mild Stress-Induced Depressive-Like Behavior by Upregulation of Sirt-1: Involvement in Suppression of Hippocampal Endoplasmic Reticulum Stress.
Liu SY, Li D, Zeng HY, Kan LY, Zou W, Zhang P, Gu HF, Tang XQ
The international journal of neuropsychopharmacology 2017 Nov 1;20(11):867-876
The international journal of neuropsychopharmacology 2017 Nov 1;20(11):867-876
Inhibition of tissue transglutaminase attenuates lipopolysaccharide-induced inflammation in glial cells through AKT/mTOR signal pathway.
Ding Y, Zhang J, Wang R
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 May;89:1310-1319
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 May;89:1310-1319
FGF7/FGFR2 signal promotes invasion and migration in human gastric cancer through upregulation of thrombospondin-1.
Huang T, Wang L, Liu D, Li P, Xiong H, Zhuang L, Sun L, Yuan X, Qiu H
International journal of oncology 2017 May;50(5):1501-1512
International journal of oncology 2017 May;50(5):1501-1512
Embelin attenuates adipogenesis and lipogenesis through activating canonical Wnt signaling and inhibits high-fat diet-induced obesity.
Gao Y, Li J, Xu X, Wang S, Yang Y, Zhou J, Zhang L, Zheng F, Li X, Wang B
International journal of obesity (2005) 2017 May;41(5):729-738
International journal of obesity (2005) 2017 May;41(5):729-738
Sulforaphane-cysteine induces apoptosis by sustained activation of ERK1/2 and caspase 3 in human glioblastoma U373MG and U87MG cells.
Wu S, Zhou Y, Yang G, Tian H, Geng Y, Hu Y, Lin K, Wu W
Oncology reports 2017 May;37(5):2829-2838
Oncology reports 2017 May;37(5):2829-2838
oxLDL antibody inhibits MCP-1 release in monocytes/macrophages by regulating Ca2+ /K+ channel flow.
Su J, Zhou H, Liu X, Nilsson J, Fredrikson GN, Zhao M
Journal of cellular and molecular medicine 2017 May;21(5):929-940
Journal of cellular and molecular medicine 2017 May;21(5):929-940
TET3-mediated DNA oxidation promotes ATR-dependent DNA damage response.
Jiang D, Wei S, Chen F, Zhang Y, Li J
EMBO reports 2017 May;18(5):781-796
EMBO reports 2017 May;18(5):781-796
Menin enhances c-Myc-mediated transcription to promote cancer progression.
Wu G, Yuan M, Shen S, Ma X, Fang J, Zhu L, Sun L, Liu Z, He X, Huang, Li T, Li C, Wu J, Hu X, Li Z, Song L, Qu K, Zhang H, Gao P
Nature communications 2017 May 5;8:15278
Nature communications 2017 May 5;8:15278
Thyroid stimulating hormone increases hepatic gluconeogenesis via CRTC2.
Li Y, Wang L, Zhou L, Song Y, Ma S, Yu C, Zhao J, Xu C, Gao L
Molecular and cellular endocrinology 2017 May 5;446:70-80
Molecular and cellular endocrinology 2017 May 5;446:70-80
Longikaurin A, a natural ent-kaurane, suppresses stemness in nasopharyngeal carcinoma cells.
Yuan Y, Du Y, Hu XY, Liu MY, Du JK, Liu XM, Yu HE, Wang TZ, Pu JX, Zhong Q, Zou QF
Oncology letters 2017 Mar;13(3):1672-1680
Oncology letters 2017 Mar;13(3):1672-1680
Hypoxia promotes chemotherapy resistance by down-regulating SKA1 gene expression in human osteosarcoma.
Ma Q, Zhang Y, Liu T, Jiang K, Wen Y, Fan Q, Qiu X
Cancer biology & therapy 2017 Mar 4;18(3):177-185
Cancer biology & therapy 2017 Mar 4;18(3):177-185
miR-148a and miR-17-5p synergistically regulate milk TAG synthesis via PPARGC1A and PPARA in goat mammary epithelial cells.
Chen Z, Luo J, Sun S, Cao D, Shi H, Loor JJ
RNA biology 2017 Mar 4;14(3):326-338
RNA biology 2017 Mar 4;14(3):326-338
MicroRNA-17-92 Regulates the Transcription Factor E2F3b during Myogenesis In Vitro and In Vivo.
Tang Z, Liu N, Luo L, Kang K, Li L, Ni R, Qiu H, Gou D
International journal of molecular sciences 2017 Mar 31;18(4)
International journal of molecular sciences 2017 Mar 31;18(4)
Probiotics may delay the progression of nonalcoholic fatty liver disease by restoring the gut microbiota structure and improving intestinal endotoxemia.
Xue L, He J, Gao N, Lu X, Li M, Wu X, Liu Z, Jin Y, Liu J, Xu J, Geng Y
Scientific reports 2017 Mar 28;7:45176
Scientific reports 2017 Mar 28;7:45176
Anti-tumor effect of evodiamine by inducing Akt-mediated apoptosis in hepatocellular carcinoma.
Yang F, Shi L, Liang T, Ji L, Zhang G, Shen Y, Zhu F, Xu L
Biochemical and biophysical research communications 2017 Mar 25;485(1):54-61
Biochemical and biophysical research communications 2017 Mar 25;485(1):54-61
Upregulation of microRNA-574-3p in a human gastric cancer cell line AGS by TGF-β1.
Zhang R, Wang M, Sui P, Ding L, Yang Q
Gene 2017 Mar 20;605:63-69
Gene 2017 Mar 20;605:63-69
Sulforaphane prevents bleomycin‑induced pulmonary fibrosis in mice by inhibiting oxidative stress via nuclear factor erythroid 2‑related factor‑2 activation.
Yan B, Ma Z, Shi S, Hu Y, Ma T, Rong G, Yang J
Molecular medicine reports 2017 Jun;15(6):4005-4014
Molecular medicine reports 2017 Jun;15(6):4005-4014
Cerebrolysin alleviates cognitive deficits induced by chronic cerebral hypoperfusion by increasing the levels of plasticity-related proteins and decreasing the levels of apoptosis-related proteins in the rat hippocampus.
Liu Z, Hu M, Lu P, Wang H, Qi Q, Xu J, Xiao Y, Fan M, Jia Y, Zhang D
Neuroscience letters 2017 Jun 9;651:72-78
Neuroscience letters 2017 Jun 9;651:72-78
CADASIL mutant NOTCH3(R90C) decreases the viability of HS683 oligodendrocytes via apoptosis.
Tang M, Shi C, Song B, Yang J, Yang T, Mao C, Li Y, Liu X, Zhang S, Wang H, Luo H, Xu Y
Molecular biology reports 2017 Jul;44(3):273-280
Molecular biology reports 2017 Jul;44(3):273-280
The MBNL3 splicing factor promotes hepatocellular carcinoma by increasing PXN expression through the alternative splicing of lncRNA-PXN-AS1.
Yuan JH, Liu XN, Wang TT, Pan W, Tao QF, Zhou WP, Wang F, Sun SH
Nature cell biology 2017 Jul;19(7):820-832
Nature cell biology 2017 Jul;19(7):820-832
Malvidin and cyanidin derivatives from açai fruit (Euterpe oleracea Mart.) counteract UV-A-induced oxidative stress in immortalized fibroblasts.
Petruk G, Illiano A, Del Giudice R, Raiola A, Amoresano A, Rigano MM, Piccoli R, Monti DM
Journal of photochemistry and photobiology. B, Biology 2017 Jul;172:42-51
Journal of photochemistry and photobiology. B, Biology 2017 Jul;172:42-51
Selenium-Containing Polysaccharide-Protein Complex in Se-Enriched Ulva fasciata Induces Mitochondria-Mediated Apoptosis in A549 Human Lung Cancer Cells.
Sun X, Zhong Y, Luo H, Yang Y
Marine drugs 2017 Jul 16;15(7)
Marine drugs 2017 Jul 16;15(7)
Deubiquitinase USP33 is negatively regulated by β-TrCP through ubiquitin-dependent proteolysis.
Cheng Q, Yuan Y, Li L, Guo T, Miao Y, Ren Y, Liu J, Feng Q, Wang X, Zhao P, Zuo Y, Qian L, Zhang L, Zheng H
Experimental cell research 2017 Jul 1;356(1):1-7
Experimental cell research 2017 Jul 1;356(1):1-7
Transcription regulator TRIP-Br2 mediates ER stress-induced brown adipocytes dysfunction.
Qiang G, Whang Kong H, Gil V, Liew CW
Scientific reports 2017 Jan 9;7:40215
Scientific reports 2017 Jan 9;7:40215
The role of the ATM/Chk/P53 pathway in mediating DNA damage in hand-foot syndrome induced by PLD.
Yang J, Qiao L, Zeng Z, Wang J, Zhu T, Wei J, Wu M, Ye S, Huang X, Ma D, Liu R, Gao Q
Toxicology letters 2017 Jan 4;265:131-139
Toxicology letters 2017 Jan 4;265:131-139
Targeting P-glycoprotein function, p53 and energy metabolism: Combination of metformin and 2-deoxyglucose reverses the multidrug resistance of MCF-7/Dox cells to doxorubicin.
Xue C, Wang C, Sun Y, Meng Q, Liu Z, Huo X, Sun P, Sun H, Ma X, Ma X, Peng J, Liu K
Oncotarget 2017 Jan 31;8(5):8622-8632
Oncotarget 2017 Jan 31;8(5):8622-8632
Knockdown of TREM-1 suppresses IL-1β-induced chondrocyte injury via inhibiting the NF-κB pathway.
Tang J, Dong Q
Biochemical and biophysical research communications 2017 Jan 22;482(4):1240-1245
Biochemical and biophysical research communications 2017 Jan 22;482(4):1240-1245
Transdifferentiation of human male germline stem cells to hepatocytes in vivo via the transplantation under renal capsules.
Chen Z, Niu M, Sun M, Yuan Q, Yao C, Hou J, Wang H, Wen L, Fu H, Zhou F, Li Z, He Z
Oncotarget 2017 Feb 28;8(9):14576-14592
Oncotarget 2017 Feb 28;8(9):14576-14592
Calycosin attenuates triglyceride accumulation and hepatic fibrosis in murine model of non-alcoholic steatohepatitis via activating farnesoid X receptor.
Duan X, Meng Q, Wang C, Liu Z, Liu Q, Sun H, Sun P, Yang X, Huo X, Peng J, Liu K
Phytomedicine : international journal of phytotherapy and phytopharmacology 2017 Feb 15;25:83-92
Phytomedicine : international journal of phytotherapy and phytopharmacology 2017 Feb 15;25:83-92
Single tumor-initiating cells evade immune clearance by recruiting type II macrophages.
Guo X, Zhao Y, Yan H, Yang Y, Shen S, Dai X, Ji X, Ji F, Gong XG, Li L, Bai X, Feng XH, Liang T, Ji J, Chen L, Wang H, Zhao B
Genes & development 2017 Feb 1;31(3):247-259
Genes & development 2017 Feb 1;31(3):247-259
Ontogeny, aging, and gender-related changes in hepatic multidrug resistant protein genes in rats.
Zhu QN, Hou WY, Xu SF, Lu YF, Liu J
Life sciences 2017 Feb 1;170:108-114
Life sciences 2017 Feb 1;170:108-114
Altered Expression of TXNIP in the peripheral leukocytes of patients with coronary atherosclerotic heart disease.
Zhang Y, Huang J, Yang X, Sun X, Xu Q, Wang B, Zhong P, Wei Z
Medicine 2017 Dec;96(49):e9108
Medicine 2017 Dec;96(49):e9108
Effects of polysaccharide from Physalis alkekengi var. francheti on liver injury and intestinal microflora in type-2 diabetic mice.
Zhao X, Chen Z, Yin Y, Li X
Pharmaceutical biology 2017 Dec;55(1):2020-2025
Pharmaceutical biology 2017 Dec;55(1):2020-2025
Induction of autophagy by an oleanolic acid derivative, SZC017, promotes ROS-dependent apoptosis through Akt and JAK2/STAT3 signaling pathway in human lung cancer cells.
Song Y, Kong L, Sun B, Gao L, Chu P, Ahsan A, Qaed E, Lin Y, Peng J, Ma X, Zhang J, Wang S, Tang Z
Cell biology international 2017 Dec;41(12):1367-1378
Cell biology international 2017 Dec;41(12):1367-1378
Glucose potentiates β-cell function by inducing Tph1 expression in rat islets.
Zhang Y, Deng R, Yang X, Xu W, Liu Y, Li F, Zhang J, Tang H, Ji X, Bi Y, Wang X, Zhou L, Ning G
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017 Dec;31(12):5342-5355
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017 Dec;31(12):5342-5355
POSH participates in epileptogenesis by increasing the surface expression of the NMDA receptor: a promising therapeutic target for epilepsy.
Wang X, Tian X, Yang Y, Lu X, Li Y, Ma Y, Zhang Y, Zheng F, Lu S, Xu D, Xu X, Wang W, Wang X
Expert opinion on therapeutic targets 2017 Dec;21(12):1083-1094
Expert opinion on therapeutic targets 2017 Dec;21(12):1083-1094
Regulation of AMH by oocyte-specific growth factors in human primary cumulus cells.
Convissar S, Armouti M, Fierro MA, Winston NJ, Scoccia H, Zamah AM, Stocco C
Reproduction (Cambridge, England) 2017 Dec;154(6):745-753
Reproduction (Cambridge, England) 2017 Dec;154(6):745-753
Effects of dimethyl carbonate-induced autophagic activation on follicular development in the mouse ovary.
Tang Z, Zhang Z, Tang Y, Qi L, Yang F, Wang Z
Experimental and therapeutic medicine 2017 Dec;14(6):5981-5989
Experimental and therapeutic medicine 2017 Dec;14(6):5981-5989
MicroRNA-30e Functions as a Tumor Suppressor in Cervical Carcinoma Cells through Targeting GALNT7.
Wu H, Chen J, Li D, Liu X, Li L, Wang K
Translational oncology 2017 Dec;10(6):876-885
Translational oncology 2017 Dec;10(6):876-885
Piperlongumine suppresses bladder cancer invasion via inhibiting epithelial mesenchymal transition and F-actin reorganization.
Liu D, Qiu XY, Wu X, Hu DX, Li CY, Yu SB, Pan F, Chen XQ
Biochemical and biophysical research communications 2017 Dec 9;494(1-2):165-172
Biochemical and biophysical research communications 2017 Dec 9;494(1-2):165-172
Salvianolic acid B protects against lipopolysaccharide-induced behavioral deficits and neuroinflammatory response: involvement of autophagy and NLRP3 inflammasome.
Jiang P, Guo Y, Dang R, Yang M, Liao D, Li H, Sun Z, Feng Q, Xu P
Journal of neuroinflammation 2017 Dec 6;14(1):239
Journal of neuroinflammation 2017 Dec 6;14(1):239
Rho/ROCK Pathway Regulates Migration and Invasion of Esophageal Squamous Cell Carcinoma by Regulating Caveolin-1.
Liu Z, Yu J, Wu R, Tang S, Cai X, Guo G, Chen S
Medical science monitor : international medical journal of experimental and clinical research 2017 Dec 30;23:6174-6185
Medical science monitor : international medical journal of experimental and clinical research 2017 Dec 30;23:6174-6185
CAPE-pNO2 ameliorated diabetic nephropathy through regulating the Akt/NF-κB/ iNOS pathway in STZ-induced diabetic mice.
Wang X, Li D, Fan L, Xiao Q, Zuo H, Li Z
Oncotarget 2017 Dec 29;8(70):114506-114525
Oncotarget 2017 Dec 29;8(70):114506-114525
Synergistic inhibition of tumor growth by combination treatment with drugs against different subpopulations of glioblastoma cells.
Chang CH, Liu WT, Hung HC, Gean CY, Tsai HM, Su CL, Gean PW
BMC cancer 2017 Dec 29;17(1):905
BMC cancer 2017 Dec 29;17(1):905
Discovery of a Small-Molecule Bromodomain-Containing Protein 4 (BRD4) Inhibitor That Induces AMP-Activated Protein Kinase-Modulated Autophagy-Associated Cell Death in Breast Cancer.
Ouyang L, Zhang L, Liu J, Fu L, Yao D, Zhao Y, Zhang S, Wang G, He G, Liu B
Journal of medicinal chemistry 2017 Dec 28;60(24):9990-10012
Journal of medicinal chemistry 2017 Dec 28;60(24):9990-10012
Cadherin 6 is activated by Epstein-Barr virus LMP1 to mediate EMT and metastasis as an interplay node of multiple pathways in nasopharyngeal carcinoma.
Zuo LL, Zhang J, Liu LZ, Zhou Q, Du SJ, Xin SY, Ning ZP, Yang J, Yu HB, Yue WX, Wang J, Zhu FX, Li GY, Lu JH
Oncogenesis 2017 Dec 22;6(12):402
Oncogenesis 2017 Dec 22;6(12):402
Ultrasound reverses chemoresistance in breast cancer stem cell like cells by altering ABCG2 expression.
Guo L, Zheng P, Fan H, Wang H, Xu W, Zhou W
Bioscience reports 2017 Dec 22;37(6)
Bioscience reports 2017 Dec 22;37(6)
Indomethacin-based stimuli-responsive micelles combined with paclitaxel to overcome multidrug resistance.
Wang S, Tan X, Li S, Zhou Y, Geng P, Hua A, Deng A, Yu Z
Oncotarget 2017 Dec 19;8(67):111281-111294
Oncotarget 2017 Dec 19;8(67):111281-111294
De novo, deleterious sequence variants that alter the transcriptional activity of the homeoprotein PBX1 are associated with intellectual disability and pleiotropic developmental defects.
Slavotinek A, Risolino M, Losa M, Cho MT, Monaghan KG, Schneidman-Duhovny D, Parisotto S, Herkert JC, Stegmann APA, Miller K, Shur N, Chui J, Muller E, DeBrosse S, Szot JO, Chapman G, Pachter NS, Winlaw DS, Mendelsohn BA, Dalton J, Sarafoglou K, Karachunski PI, Lewis JM, Pedro H, Dunwoodie SL, Selleri L, Shieh J
Human molecular genetics 2017 Dec 15;26(24):4849-4860
Human molecular genetics 2017 Dec 15;26(24):4849-4860
Ascl2 activation by YAP1/KLF5 ensures the self-renewability of colon cancer progenitor cells.
Wei X, Ye J, Shang Y, Chen H, Liu S, Liu L, Wang R
Oncotarget 2017 Dec 12;8(65):109301-109318
Oncotarget 2017 Dec 12;8(65):109301-109318
Adeno-associated virus 9-mediated Cdk5 inhibitory peptide reverses pathologic changes and behavioral deficits in the Alzheimer's disease mouse model.
He Y, Pan S, Xu M, He R, Huang W, Song P, Huang J, Zhang HT, Hu Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017 Aug;31(8):3383-3392
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017 Aug;31(8):3383-3392
Effect of GAPT extract on expression of tau protein and its phosphorylation related enzymes in hippocampal neurons of APPV717I transgenic mice.
Ni JN, Shi J, Zhang XK, Yang YC, Liu XM, Wei MQ, Li T, Wang PW, Tian JZ, Wang YY
Chinese journal of integrative medicine 2017 Aug;23(8):605-610
Chinese journal of integrative medicine 2017 Aug;23(8):605-610
Ubiquitin C-terminal hydrolase-L3 promotes interferon antiviral activity by stabilizing type I-interferon receptor.
Zhao P, Guo T, Qian L, Wang X, Yuan Y, Cheng Q, Zuo Y, Liu J, Miao Y, Feng Q, Zhang L, Wu S, Zheng H
Antiviral research 2017 Aug;144:120-129
Antiviral research 2017 Aug;144:120-129
Palbociclib induces activation of AMPK and inhibits hepatocellular carcinoma in a CDK4/6-independent manner.
Hsieh FS, Chen YL, Hung MH, Chu PY, Tsai MH, Chen LJ, Hsiao YJ, Shih CT, Chang MJ, Chao TI, Shiau CW, Chen KF
Molecular oncology 2017 Aug;11(8):1035-1049
Molecular oncology 2017 Aug;11(8):1035-1049
NFATc3 mediates the sensitivity of gastric cancer cells to arsenic sulfide.
Zhang X, Kang T, Zhang L, Tong Y, Ding W, Chen S
Oncotarget 2017 Aug 8;8(32):52735-52745
Oncotarget 2017 Aug 8;8(32):52735-52745
Apoptosis pattern and alterations of expression of apoptosis-related factors of supporting cells in Kölliker's organ in vivo in early stage after birth in rats.
Liu J, Cai L, He Y, Yang J
European journal of histochemistry : EJH 2017 Aug 7;61(3):2706
European journal of histochemistry : EJH 2017 Aug 7;61(3):2706
Enteric dysbiosis-linked gut barrier disruption triggers early renal injury induced by chronic high salt feeding in mice.
Hu J, Luo H, Wang J, Tang W, Lu J, Wu S, Xiong Z, Yang G, Chen Z, Lan T, Zhou H, Nie J, Jiang Y, Chen P
Experimental & molecular medicine 2017 Aug 25;49(8):e370
Experimental & molecular medicine 2017 Aug 25;49(8):e370
Structure-based virtual screening and optimization of modulators targeting Hsp90-Cdc37 interaction.
Wang L, Li L, Zhou ZH, Jiang ZY, You QD, Xu XL
European journal of medicinal chemistry 2017 Aug 18;136:63-73
European journal of medicinal chemistry 2017 Aug 18;136:63-73
Exogenous H2S facilitating ubiquitin aggregates clearance via autophagy attenuates type 2 diabetes-induced cardiomyopathy.
Wu J, Tian Z, Sun Y, Lu C, Liu N, Gao Z, Zhang L, Dong S, Yang F, Zhong X, Xu C, Lu F, Zhang W
Cell death & disease 2017 Aug 10;8(8):e2992
Cell death & disease 2017 Aug 10;8(8):e2992
High expression of RBM8A predicts poor patient prognosis and promotes tumor progression in hepatocellular carcinoma.
Liang R, Lin Y, Ye JZ, Yan XX, Liu ZH, Li YQ, Luo XL, Ye HH
Oncology reports 2017 Apr;37(4):2167-2176
Oncology reports 2017 Apr;37(4):2167-2176
Upregulated unique long 16 binding protein 1 detected in preeclamptic placenta affects human extravillous trophoblast cell line (HTR-8/SVneo) invasion by modulating the function of uterine natural killer cells.
Liu J, Song G, Lin X, Pang X, Meng T
Experimental and therapeutic medicine 2017 Apr;13(4):1447-1455
Experimental and therapeutic medicine 2017 Apr;13(4):1447-1455
Endogenous Stem Cells Were Recruited by Defocused Low-Energy Shock Wave in Treating Diabetic Bladder Dysfunction.
Jin Y, Xu L, Zhao Y, Wang M, Jin X, Zhang H
Stem cell reviews and reports 2017 Apr;13(2):287-298
Stem cell reviews and reports 2017 Apr;13(2):287-298
Autoinhibition of Dishevelled protein regulated by its extreme C terminus plays a distinct role in Wnt/β-catenin and Wnt/planar cell polarity (PCP) signaling pathways.
Qi J, Lee HJ, Saquet A, Cheng XN, Shao M, Zheng JJ, Shi DL
The Journal of biological chemistry 2017 Apr 7;292(14):5898-5908
The Journal of biological chemistry 2017 Apr 7;292(14):5898-5908
A novel glutaminase inhibitor-968 inhibits the migration and proliferation of non-small cell lung cancer cells by targeting EGFR/ERK signaling pathway.
Han T, Guo M, Zhang T, Gan M, Xie C, Wang JB
Oncotarget 2017 Apr 25;8(17):28063-28073
Oncotarget 2017 Apr 25;8(17):28063-28073
Tenofovir and adefovir down-regulate mitochondrial chaperone TRAP1 and succinate dehydrogenase subunit B to metabolically reprogram glucose metabolism and induce nephrotoxicity.
Zhao X, Sun K, Lan Z, Song W, Cheng L, Chi W, Chen J, Huo Y, Xu L, Liu X, Deng H, Siegenthaler JA, Chen L
Scientific reports 2017 Apr 11;7:46344
Scientific reports 2017 Apr 11;7:46344
Discovery of a small molecule targeting ULK1-modulated cell death of triple negative breast cancer in vitro and in vivo.
Zhang L, Fu L, Zhang S, Zhang J, Zhao Y, Zheng Y, He G, Yang S, Ouyang L, Liu B
Chemical science 2017 Apr 1;8(4):2687-2701
Chemical science 2017 Apr 1;8(4):2687-2701
The role of TGF-β-activated kinase 1 in db/db mice and high glucose-induced macrophage.
Xu X, Fan Z, Qi X, Shao Y, Wu Y
International immunopharmacology 2016 Sep;38:120-31
International immunopharmacology 2016 Sep;38:120-31
B7-H4 expression in human infiltrating ductal carcinoma‑associated macrophages.
Liu L, Li D, Chen S, Zhao R, Pang D, Li D, Fu Z
Molecular medicine reports 2016 Sep;14(3):2135-42
Molecular medicine reports 2016 Sep;14(3):2135-42
Interleukin-11 promotes epithelial-mesenchymal transition in anaplastic thyroid carcinoma cells through PI3K/Akt/GSK3β signaling pathway activation.
Zhong Z, Hu Z, Jiang Y, Sun R, Chen X, Chu H, Zeng M, Sun C
Oncotarget 2016 Sep 13;7(37):59652-59663
Oncotarget 2016 Sep 13;7(37):59652-59663
Functional characterization of hepatitis B virus core promoter mutants revealed transcriptional interference among co-terminal viral mRNAs.
Chen C, Jia H, Zhang F, Qin Y, Zong L, Yuan Q, Wang Y, Xia N, Li J, Wen Y, Tong S
The Journal of general virology 2016 Oct;97(10):2668-2676
The Journal of general virology 2016 Oct;97(10):2668-2676
Effect of Polygonatum odoratum extract on human breast cancer MDA-MB-231 cell proliferation and apoptosis.
Tai Y, Sun YM, Zou X, Pan Q, Lan YD, Huo Q, Zhu JW, Guo F, Zheng CQ, Wu CZ, Liu H
Experimental and therapeutic medicine 2016 Oct;12(4):2681-2687
Experimental and therapeutic medicine 2016 Oct;12(4):2681-2687
Afamin promotes glucose metabolism in papillary thyroid carcinoma.
Shen CT, Wei WJ, Qiu ZL, Song HJ, Luo QY
Molecular and cellular endocrinology 2016 Oct 15;434:108-15
Molecular and cellular endocrinology 2016 Oct 15;434:108-15
MicroRNA-181b suppresses TAG via target IRS2 and regulating multiple genes in the Hippo pathway.
Chen Z, Shi H, Sun S, Xu H, Cao D, Luo J
Experimental cell research 2016 Oct 15;348(1):66-74
Experimental cell research 2016 Oct 15;348(1):66-74
HSPB1 deficiency sensitizes melanoma cells to hyperthermia induced cell death.
Wang HX, Yang Y, Guo H, Hou DD, Zheng S, Hong YX, Cai YF, Huo W, Qi RQ, Zhang L, Chen HD, Gao XH
Oncotarget 2016 Oct 11;7(41):67449-67462
Oncotarget 2016 Oct 11;7(41):67449-67462
A comparison of incidences of bladder neck contracture of 80- versus 180-W GreenLight laser photoselective vaporization of benign prostatic hyperplasia.
Hu B, Song Z, Liu H, Qiao L, Zhao Y, Wang M, Song W, Zhang D, Jin X, Zhang H
Lasers in medical science 2016 Nov;31(8):1573-1581
Lasers in medical science 2016 Nov;31(8):1573-1581
Ubiquitin-dependent Turnover of Adenosine Deaminase Acting on RNA 1 (ADAR1) Is Required for Efficient Antiviral Activity of Type I Interferon.
Li L, Qian G, Zuo Y, Yuan Y, Cheng Q, Guo T, Liu J, Liu C, Zhang L, Zheng H
The Journal of biological chemistry 2016 Nov 25;291(48):24974-24985
The Journal of biological chemistry 2016 Nov 25;291(48):24974-24985
Human epithelial-type ovarian tumour marker beta-2-microglobulin is regulated by the TGF-β signaling pathway.
Sun W, Gui L, Zuo X, Zhang L, Zhou D, Duan X, Ren W, Xu G
Journal of translational medicine 2016 Mar 16;14:75
Journal of translational medicine 2016 Mar 16;14:75
AMPK activation protects cells from oxidative stress-induced senescence via autophagic flux restoration and intracellular NAD(+) elevation.
Han X, Tai H, Wang X, Wang Z, Zhou J, Wei X, Ding Y, Gong H, Mo C, Zhang J, Qin J, Ma Y, Huang N, Xiang R, Xiao H
Aging cell 2016 Jun;15(3):416-27
Aging cell 2016 Jun;15(3):416-27
Pancreatic cancer risk variant in LINC00673 creates a miR-1231 binding site and interferes with PTPN11 degradation.
Zheng J, Huang X, Tan W, Yu D, Du Z, Chang J, Wei L, Han Y, Wang C, Che X, Zhou Y, Miao X, Jiang G, Yu X, Yang X, Cao G, Zuo C, Li Z, Wang C, Cheung ST, Jia Y, Zheng X, Shen H, Wu C, Lin D
Nature genetics 2016 Jul;48(7):747-57
Nature genetics 2016 Jul;48(7):747-57
Deubiquitinase USP2a Sustains Interferons Antiviral Activity by Restricting Ubiquitination of Activated STAT1 in the Nucleus.
Ren Y, Zhao P, Liu J, Yuan Y, Cheng Q, Zuo Y, Qian L, Liu C, Guo T, Zhang L, Wang X, Qian G, Li L, Ge J, Dai J, Xiong S, Zheng H
PLoS pathogens 2016 Jul;12(7):e1005764
PLoS pathogens 2016 Jul;12(7):e1005764
Homologous recombination-dependent repair of telomeric DSBs in proliferating human cells.
Mao P, Liu J, Zhang Z, Zhang H, Liu H, Gao S, Rong YS, Zhao Y
Nature communications 2016 Jul 11;7:12154
Nature communications 2016 Jul 11;7:12154
Blockade of TGF-β-activated kinase 1 prevents advanced glycation end products-induced inflammatory response in macrophages.
Xu X, Qi X, Shao Y, Li Y, Fu X, Feng S, Wu Y
Cytokine 2016 Feb;78:62-8
Cytokine 2016 Feb;78:62-8
The PLC/PKC/Ras/MEK/Kv channel pathway is involved in uncarboxylated osteocalcin-regulated insulin secretion in rats.
Gao J, Bai T, Ren L, Ding Y, Zhong X, Wang H, Guo Y, Li J, Liu Y, Zhang Y
Peptides 2016 Dec;86:72-79
Peptides 2016 Dec;86:72-79
Nuclear PTEN interferes with binding of Ku70 at double-strand breaks through post-translational poly(ADP-ribosyl)ation.
Guan J, Zhao Q, Mao W
Biochimica et biophysica acta 2016 Dec;1863(12):3106-3115
Biochimica et biophysica acta 2016 Dec;1863(12):3106-3115
Berberine increases adipose triglyceride lipase in 3T3-L1 adipocytes through the AMPK pathway.
Jiang D, Wang D, Zhuang X, Wang Z, Ni Y, Chen S, Sun F
Lipids in health and disease 2016 Dec 9;15(1):214
Lipids in health and disease 2016 Dec 9;15(1):214
Senescence: novel insight into DLX3 mutations leading to enhanced bone formation in Tricho-Dento-Osseous syndrome.
Zhao N, Han D, Liu H, Li Y, Wong SW, Cao Z, Xu J, Zhang X, Cai T, Wang Y, Feng H
Scientific reports 2016 Dec 7;6:38680
Scientific reports 2016 Dec 7;6:38680
H2O2 treatment or serum deprivation induces autophagy and apoptosis in naked mole-rat skin fibroblasts by inhibiting the PI3K/Akt signaling pathway.
Zhao S, Li L, Wang S, Yu C, Xiao B, Lin L, Cong W, Cheng J, Yang W, Sun W, Cui S
Oncotarget 2016 Dec 20;7(51):84839-84850
Oncotarget 2016 Dec 20;7(51):84839-84850
Chronic stress and excessive glucocorticoid exposure both lead to altered Neuregulin-1/ErbB signaling in rat myocardium.
Dang R, Guo Y, Zhang L, Chen L, Yang R, Jiang P
Steroids 2016 Aug;112:47-53
Steroids 2016 Aug;112:47-53
YB-1 regulates tiRNA-induced Stress Granule formation but not translational repression.
Lyons SM, Achorn C, Kedersha NL, Anderson PJ, Ivanov P
Nucleic acids research 2016 Aug 19;44(14):6949-60
Nucleic acids research 2016 Aug 19;44(14):6949-60
Enhanced SLC34A2 in breast cancer stem cell-like cells induces chemotherapeutic resistance to doxorubicin via SLC34A2-Bmi1-ABCC5 signaling.
Ge G, Zhou C, Ren Y, Tang X, Wang K, Zhang W, Niu L, Zhou Y, Yan Y, He J
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Apr;37(4):5049-62
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Apr;37(4):5049-62
Protective effect of melatonin on myenteric neuron damage in experimental colitis in rats.
Shang B, Shi H, Wang X, Guo X, Wang N, Wang Y, Dong L
Fundamental & clinical pharmacology 2016 Apr;30(2):117-27
Fundamental & clinical pharmacology 2016 Apr;30(2):117-27
Arsenic sulfide, the main component of realgar, a traditional Chinese medicine, induces apoptosis of gastric cancer cells in vitro and in vivo.
Zhang L, Tian W, Kim S, Ding W, Tong Y, Chen S
Drug design, development and therapy 2015;9:79-92
Drug design, development and therapy 2015;9:79-92
Cardiac microvascular barrier function mediates the protection of Tongxinluo against myocardial ischemia/reperfusion injury.
Qi K, Li L, Li X, Zhao J, Wang Y, You S, Hu F, Zhang H, Cheng Y, Kang S, Cui H, Duan L, Jin C, Zheng Q, Yang Y
PloS one 2015;10(3):e0119846
PloS one 2015;10(3):e0119846
Elevated GAPDH expression is associated with the proliferation and invasion of lung and esophageal squamous cell carcinomas.
Hao L, Zhou X, Liu S, Sun M, Song Y, Du S, Sun B, Guo C, Gong L, Hu J, Guan H, Shao S
Proteomics 2015 Sep;15(17):3087-100
Proteomics 2015 Sep;15(17):3087-100
Gabarapl1 mediates androgen-regulated autophagy in prostate cancer.
Xie CW, Zhou Y, Liu SL, Fang ZY, Su B, Zhang W
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2015 Nov;36(11):8727-33
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2015 Nov;36(11):8727-33
MiR-101 sensitizes human nasopharyngeal carcinoma cells to radiation by targeting stathmin 1.
Sun Q, Liu T, Zhang T, Du S, Xie GX, Lin X, Chen L, Yuan Y
Molecular medicine reports 2015 May;11(5):3330-6
Molecular medicine reports 2015 May;11(5):3330-6
Formaldehyde exposure induces autophagy in testicular tissues of adult male rats.
Han SP, Zhou DX, Lin P, Qin Z, An L, Zheng LR, Lei L
Environmental toxicology 2015 Mar;30(3):323-31
Environmental toxicology 2015 Mar;30(3):323-31
Astrocyte elevated gene-1 promotes progression of cervical squamous cell carcinoma by inducing epithelial-mesenchymal transition via Wnt signaling.
Song E, Yu W, Xiong X, Kuang X, Ai Y, Xiong X
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 2015 Mar;25(3):345-55
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 2015 Mar;25(3):345-55
MiR-200c inhibits autophagy and enhances radiosensitivity in breast cancer cells by targeting UBQLN1.
Sun Q, Liu T, Yuan Y, Guo Z, Xie G, Du S, Lin X, Xu Z, Liu M, Wang W, Yuan Q, Chen L
International journal of cancer 2015 Mar 1;136(5):1003-12
International journal of cancer 2015 Mar 1;136(5):1003-12
G-protein coupled receptor 34 activates Erk and phosphatidylinositol 3-kinase/Akt pathways and functions as alternative pathway to mediate p185Bcr-Abl-induced transformation and leukemogenesis.
Zuo B, Li M, Liu Y, Li K, Ma S, Cui M, Qin Y, Zhu H, Pan X, Guo J, Dai Z, Yu W
Leukemia & lymphoma 2015 Jul;56(7):2170-81
Leukemia & lymphoma 2015 Jul;56(7):2170-81
8-p-Hdroxybenzoyl Tovarol Induces Paraptosis Like Cell Death and Protective Autophagy in Human Cervical Cancer HeLa Cells.
Zhang C, Jiang Y, Zhang J, Huang J, Wang J
International journal of molecular sciences 2015 Jul 2;16(7):14979-96
International journal of molecular sciences 2015 Jul 2;16(7):14979-96
Annexin A3 as a potential target for immunotherapy of liver cancer stem-like cells.
Pan QZ, Pan K, Wang QJ, Weng DS, Zhao JJ, Zheng HX, Zhang XF, Jiang SS, Lv L, Tang Y, Li YQ, He J, Liu Q, Chen CL, Zhang HX, Xia JC
Stem cells (Dayton, Ohio) 2015 Feb;33(2):354-66
Stem cells (Dayton, Ohio) 2015 Feb;33(2):354-66
Inhibition of JNK3 promotes apoptosis induced by BH3 mimetic S1 in chemoresistant human ovarian cancer cells.
Yang X, Xiang X, Xia M, Su J, Wu Y, Shen L, Xu Y, Sun L
Anatomical record (Hoboken, N.J. : 2007) 2015 Feb;298(2):386-95
Anatomical record (Hoboken, N.J. : 2007) 2015 Feb;298(2):386-95
Decreased expression of mucin-1 in endometriosis endometrium correlated with progesterone receptor B involved in infertility.
Shen F, Yan C, Liu M, Feng Y, Chen Y
Archives of gynecology and obstetrics 2015 Feb;291(2):439-45
Archives of gynecology and obstetrics 2015 Feb;291(2):439-45
Tolerance to endoplasmic reticulum stress mediates cisplatin resistance in human ovarian cancer cells by maintaining endoplasmic reticulum and mitochondrial homeostasis.
Xu Y, Wang C, Su J, Xie Q, Ma L, Zeng L, Yu Y, Liu S, Li S, Li Z, Sun L
Oncology reports 2015 Dec;34(6):3051-60
Oncology reports 2015 Dec;34(6):3051-60
IFIT5 positively regulates NF-κB signaling through synergizing the recruitment of IκB kinase (IKK) to TGF-β-activated kinase 1 (TAK1).
Zheng C, Zheng Z, Zhang Z, Meng J, Liu Y, Ke X, Hu Q, Wang H
Cellular signalling 2015 Dec;27(12):2343-54
Cellular signalling 2015 Dec;27(12):2343-54
Mitophagy in APPsw/PS1dE9 transgenic mice and APPsw stably expressing in HEK293 cells.
Wang X, Zhao XL, Xu LL, Wang CF, Wei LF, Liu Z, Yang H, Wang P, Xie ZH, Bi JZ
European review for medical and pharmacological sciences 2015 Dec;19(23):4595-602
European review for medical and pharmacological sciences 2015 Dec;19(23):4595-602
G1/S Cell Cycle Checkpoint Dysfunction in Lymphoblasts from Sporadic Parkinson's Disease Patients.
Esteras N, Alquézar C, Bartolomé F, de la Encarnación A, Bermejo-Pareja F, Molina JA, Martín-Requero Á
Molecular neurobiology 2015 Aug;52(1):386-98
Molecular neurobiology 2015 Aug;52(1):386-98
Lentivirus vector-mediated gene transduction of CNGRC peptide in rat adipose stem cells.
Meng D, Liu R, Pei L, Hou L, Ning Q, Yu Q, Feng L, Zhao X
Molecular medicine reports 2015 Apr;11(4):2555-61
Molecular medicine reports 2015 Apr;11(4):2555-61
Neuropilin-1 promotes epithelial-to-mesenchymal transition by stimulating nuclear factor-kappa B and is associated with poor prognosis in human oral squamous cell carcinoma.
Chu W, Song X, Yang X, Ma L, Zhu J, He M, Wang Z, Wu Y
PloS one 2014;9(7):e101931
PloS one 2014;9(7):e101931
Altered expression of hypoxia-inducible factor-1α (HIF-1α) and its regulatory genes in gastric cancer tissues.
Wang J, Ni Z, Duan Z, Wang G, Li F
PloS one 2014;9(6):e99835
PloS one 2014;9(6):e99835
Proteomics approaches for identification of tumor relevant protein targets in pulmonary squamous cell carcinoma by 2D-DIGE-MS.
Lihong H, Linlin G, Yiping G, Yang S, Xiaoyu Q, Zhuzhu G, Xiaohan Y, Xin Z, Liyan X, Shujuan S
PloS one 2014;9(4):e95121
PloS one 2014;9(4):e95121
The association of HMGB1 gene with the prognosis of HCC.
Xiao J, Ding Y, Huang J, Li Q, Liu Y, Ni W, Zhang Y, Zhu Y, Chen L, Chen B
PloS one 2014;9(2):e89097
PloS one 2014;9(2):e89097
Tetramethylpyrazine ameliorates high glucose-induced endothelial dysfunction by increasing mitochondrial biogenesis.
Xu Q, Xia P, Li X, Wang W, Liu Z, Gao X
PloS one 2014;9(2):e88243
PloS one 2014;9(2):e88243
Prognostic value of myeloid differentiation primary response 88 and Toll-like receptor 4 in breast cancer patients.
Ma FJ, Liu ZB, Hu X, Ling H, Li S, Wu J, Shao ZM
PloS one 2014;9(10):e111639
PloS one 2014;9(10):e111639
Elevated MiR-222-3p promotes proliferation and invasion of endometrial carcinoma via targeting ERα.
Liu B, Che Q, Qiu H, Bao W, Chen X, Lu W, Li B, Wan X
PloS one 2014;9(1):e87563
PloS one 2014;9(1):e87563
Matrix metalloproteinase 3 promotes cellular anti-dengue virus response via interaction with transcription factor NFκB in cell nucleus.
Zuo X, Pan W, Feng T, Shi X, Dai J
PloS one 2014;9(1):e84748
PloS one 2014;9(1):e84748
Cytotoxicity induced by nanobacteria and nanohydroxyapatites in human choriocarcinoma cells.
Zhang M, Yang J, Shu J, Fu C, Liu S, Xu G, Zhang D
Nanoscale research letters 2014;9(1):616
Nanoscale research letters 2014;9(1):616
PNMA1 promotes cell growth in human pancreatic ductal adenocarcinoma.
Jiang SH, He P, Ma MZ, Wang Y, Li RK, Fang F, Fu Y, Tian GA, Qin WX, Zhang ZG
International journal of clinical and experimental pathology 2014;7(7):3827-35
International journal of clinical and experimental pathology 2014;7(7):3827-35
mTOR inhibitor AZD8055 inhibits proliferation and induces apoptosis in laryngeal carcinoma.
Zhao L, Teng B, Wen L, Feng Q, Wang H, Li N, Wang Y, Liang Z
International journal of clinical and experimental medicine 2014;7(2):337-47
International journal of clinical and experimental medicine 2014;7(2):337-47
Involvement of TLR4 in oxidized LDL/β2GPI/anti-β2GPI-induced transformation of macrophages to foam cells.
Zhang X, Xie Y, Zhou H, Xu Y, Liu J, Xie H, Yan J
Journal of atherosclerosis and thrombosis 2014;21(11):1140-51
Journal of atherosclerosis and thrombosis 2014;21(11):1140-51
Ganoderma lucidum polysaccharides target a Fas/caspase dependent pathway to induce apoptosis in human colon cancer cells.
Liang Z, Guo YT, Yi YJ, Wang RC, Hu QL, Xiong XY
Asian Pacific journal of cancer prevention : APJCP 2014;15(9):3981-6
Asian Pacific journal of cancer prevention : APJCP 2014;15(9):3981-6
Atorvastatin induces autophagy of mesenchymal stem cells under hypoxia and serum deprivation conditions by activating the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway.
Li N, Zhang Q, Qian H, Jin C, Yang Y, Gao R
Chinese medical journal 2014;127(6):1046-51
Chinese medical journal 2014;127(6):1046-51
Geniposide and its iridoid analogs exhibit antinociception by acting at the spinal GLP-1 receptors.
Gong N, Fan H, Ma AN, Xiao Q, Wang YX
Neuropharmacology 2014 Sep;84:31-45
Neuropharmacology 2014 Sep;84:31-45
Cryopreserved mouse fetal liver stromal cells treated with mitomycin C are able to support the growth of human embryonic stem cells.
Zhang W, Hu J, Ma Q, Hu S, Wang Y, Wen X, Ma Y, Xu H, Qian H, Xu W
Experimental and therapeutic medicine 2014 Sep;8(3):935-942
Experimental and therapeutic medicine 2014 Sep;8(3):935-942
USP33, a new player in lung cancer, mediates Slit-Robo signaling.
Wen P, Kong R, Liu J, Zhu L, Chen X, Li X, Nie Y, Wu K, Wu JY
Protein & cell 2014 Sep;5(9):704-13
Protein & cell 2014 Sep;5(9):704-13
Neuroprotective role of BNIP3 under oxidative stress through autophagy in neuroblastoma cells.
Awan MU, Hasan M, Iqbal J, Lei R, Lee WF, Hong M, Qing H, Deng Y
Molecular biology reports 2014 Sep;41(9):5729-34
Molecular biology reports 2014 Sep;41(9):5729-34
Dysregulation of vitamin D metabolism in the brain and myocardium of rats following prolonged exposure to dexamethasone.
Jiang P, Xue Y, Li HD, Liu YP, Cai HL, Tang MM, Zhang LH
Psychopharmacology 2014 Sep;231(17):3445-51
Psychopharmacology 2014 Sep;231(17):3445-51
In vitro and in vivo protection against enterovirus 71 by an antisense phosphorothioate oligonucleotide.
Liu J, Zhou Z, Li K, Han M, Yang J, Wang S
Archives of virology 2014 Sep;159(9):2339-47
Archives of virology 2014 Sep;159(9):2339-47
Lipoxin A4 methyl ester ameliorates cognitive deficits induced by chronic cerebral hypoperfusion through activating ERK/Nrf2 signaling pathway in rats.
Jin W, Jia Y, Huang L, Wang T, Wang H, Dong Y, Zhang H, Fan M, Lv P
Pharmacology, biochemistry, and behavior 2014 Sep;124:145-52
Pharmacology, biochemistry, and behavior 2014 Sep;124:145-52
Direct interaction of 14-3-3ζ with ezrin promotes cell migration by regulating the formation of membrane ruffle.
Chen M, Liu T, Xu L, Gao X, Liu X, Wang C, He Q, Zhang G, Liu L
Journal of molecular biology 2014 Sep 9;426(18):3118-3133
Journal of molecular biology 2014 Sep 9;426(18):3118-3133
Loss of Wdfy3 in mice alters cerebral cortical neurogenesis reflecting aspects of the autism pathology.
Orosco LA, Ross AP, Cates SL, Scott SE, Wu D, Sohn J, Pleasure D, Pleasure SJ, Adamopoulos IE, Zarbalis KS
Nature communications 2014 Sep 8;5:4692
Nature communications 2014 Sep 8;5:4692
Bone marrow mesenchymal stem cells repair spinal cord ischemia/reperfusion injury by promoting axonal growth and anti-autophagy.
Yin F, Meng C, Lu R, Li L, Zhang Y, Chen H, Qin Y, Guo L
Neural regeneration research 2014 Sep 15;9(18):1665-71
Neural regeneration research 2014 Sep 15;9(18):1665-71
A central role for TRPS1 in the control of cell cycle and cancer development.
Wu L, Wang Y, Liu Y, Yu S, Xie H, Shi X, Qin S, Ma F, Tan TZ, Thiery JP, Chen L
Oncotarget 2014 Sep 15;5(17):7677-90
Oncotarget 2014 Sep 15;5(17):7677-90
Cationic poly(amidoamine) dendrimers induced cyto-protective autophagy in hepatocellular carcinoma cells.
Li Y, Wang S, Wang Z, Qian X, Fan J, Zeng X, Sun Y, Song P, Feng M, Ju D
Nanotechnology 2014 Sep 12;25(36):365101
Nanotechnology 2014 Sep 12;25(36):365101
Ezrin is required for epithelial-mesenchymal transition induced by TGF-β1 in A549 cells.
Chen MJ, Gao XJ, Xu LN, Liu TF, Liu XH, Liu LX
International journal of oncology 2014 Oct;45(4):1515-22
International journal of oncology 2014 Oct;45(4):1515-22
Novel microRNA-like viral small regulatory RNAs arising during human hepatitis A virus infection.
Shi J, Sun J, Wang B, Wu M, Zhang J, Duan Z, Wang H, Hu N, Hu Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2014 Oct;28(10):4381-93
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2014 Oct;28(10):4381-93
Tetrachloro-p-benzoquinone induces hepatic oxidative damage and inflammatory response, but not apoptosis in mouse: the prevention of curcumin.
Xu D, Hu L, Su C, Xia X, Zhang P, Fu J, Wang W, Xu D, Du H, Hu Q, Song E, Song Y
Toxicology and applied pharmacology 2014 Oct 15;280(2):305-13
Toxicology and applied pharmacology 2014 Oct 15;280(2):305-13
Chronic stress causes neuroendocrine-immune disturbances without affecting renal vitamin D metabolism in rats.
Jiang P, Zhang L, Zhu W, Li H, Dang R, Tang M
Journal of endocrinological investigation 2014 Nov;37(11):1109-16
Journal of endocrinological investigation 2014 Nov;37(11):1109-16
MicroRNA-145 inhibits cell proliferation by directly targeting ADAM17 in hepatocellular carcinoma.
Liu Y, Wu C, Wang Y, Wen S, Wang J, Chen Z, He Q, Feng D
Oncology reports 2014 Nov;32(5):1923-30
Oncology reports 2014 Nov;32(5):1923-30
Toxic effects of levofloxacin on rat annulus fibrosus cells: an in-vitro study.
Bai ZL, Chen Q, Yang SD, Zhang F, Wang HY, Yang DL, Ding WY
Medical science monitor : international medical journal of experimental and clinical research 2014 Nov 8;20:2205-12
Medical science monitor : international medical journal of experimental and clinical research 2014 Nov 8;20:2205-12
Cholesterol-conjugated let-7a mimics: antitumor efficacy on hepatocellular carcinoma in vitro and in a preclinical orthotopic xenograft model of systemic therapy.
Liu YM, Xia Y, Dai W, Han HY, Dong YX, Cai J, Zeng X, Luo FY, Yang T, Li YZ, Chen J, Guan J
BMC cancer 2014 Nov 28;14:889
BMC cancer 2014 Nov 28;14:889
Phosphatidylinositol 3-kinase CB association with preoperative radiotherapy response in rectal adenocarcinoma.
Yu WD, Peng YF, Pan HD, Wang L, Li K, Gu J
World journal of gastroenterology 2014 Nov 21;20(43):16258-67
World journal of gastroenterology 2014 Nov 21;20(43):16258-67
Levels of human replication factor C4, a clamp loader, correlate with tumor progression and predict the prognosis for colorectal cancer.
Xiang J, Fang L, Luo Y, Yang Z, Liao Y, Cui J, Huang M, Yang Z, Huang Y, Fan X, Wang H, Wang L, Peng J, Wang J
Journal of translational medicine 2014 Nov 19;12:320
Journal of translational medicine 2014 Nov 19;12:320
Curcumin improves the integrity of blood-spinal cord barrier after compressive spinal cord injury in rats.
Yu DS, Cao Y, Mei XF, Wang YF, Fan ZK, Wang YS, Lv G
Journal of the neurological sciences 2014 Nov 15;346(1-2):51-9
Journal of the neurological sciences 2014 Nov 15;346(1-2):51-9
The sodium channel β1 subunit mediates outgrowth of neurite-like processes on breast cancer cells and promotes tumour growth and metastasis.
Nelson M, Millican-Slater R, Forrest LC, Brackenbury WJ
International journal of cancer 2014 Nov 15;135(10):2338-51
International journal of cancer 2014 Nov 15;135(10):2338-51
17β-Estradiol protects against apoptosis induced by levofloxacin in rat nucleus pulposus cells by upregulating integrin α2β1.
Yang SD, Ma L, Gu TX, Ding WY, Zhang F, Shen Y, Zhang YZ, Yang DL, Zhang D, Sun YP, Song YL
Apoptosis : an international journal on programmed cell death 2014 May;19(5):789-800
Apoptosis : an international journal on programmed cell death 2014 May;19(5):789-800
Nitro-oleic acid downregulates lipoprotein-associated phospholipase A2 expression via the p42/p44 MAPK and NFκB pathways.
Wang G, Ji Y, Li Z, Han X, Guo N, Song Q, Quan L, Wang T, Han W, Pang D, Ouyang H, Tang X
Scientific reports 2014 May 9;4:4905
Scientific reports 2014 May 9;4:4905
Microcystin-LR stabilizes c-myc protein by inhibiting protein phosphatase 2A in HEK293 cells.
Fan H, Cai Y, Xie P, Xiao W, Chen J, Ji W, Zhao S
Toxicology 2014 May 7;319:69-74
Toxicology 2014 May 7;319:69-74
Chemical characterization and antitumor activities of polysaccharide extracted from Ganoderma lucidum.
Liang Z, Yi Y, Guo Y, Wang R, Hu Q, Xiong X
International journal of molecular sciences 2014 May 22;15(5):9103-16
International journal of molecular sciences 2014 May 22;15(5):9103-16
A caspase-dependent pathway is involved in Wnt/β-catenin signaling promoted apoptosis in Bacillus Calmette-Guerin infected RAW264.7 macrophages.
Wu X, Deng G, Hao X, Li Y, Zeng J, Ma C, He Y, Liu X, Wang Y
International journal of molecular sciences 2014 Mar 21;15(3):5045-62
International journal of molecular sciences 2014 Mar 21;15(3):5045-62
HMG-CoA reductase is negatively associated with PCV2 infection and PCV2-induced apoptotic cell death.
Yang X, Ouyang H, Chen F, Pang D, Dong M, Yang S, Liu X, Peng Z, Wang F, Zhang X, Ren L
The Journal of general virology 2014 Jun;95(Pt 6):1330-1337
The Journal of general virology 2014 Jun;95(Pt 6):1330-1337
Downregulation of p16(ink4a) inhibits cell proliferation and induces G1 cell cycle arrest in cervical cancer cells.
Zhang CY, Bao W, Wang LH
International journal of molecular medicine 2014 Jun;33(6):1577-85
International journal of molecular medicine 2014 Jun;33(6):1577-85
Zebrafish Cacna1fa is required for cone photoreceptor function and synaptic ribbon formation.
Jia S, Muto A, Orisme W, Henson HE, Parupalli C, Ju B, Baier H, Taylor MR
Human molecular genetics 2014 Jun 1;23(11):2981-94
Human molecular genetics 2014 Jun 1;23(11):2981-94
TNF-α promotes early atherosclerosis by increasing transcytosis of LDL across endothelial cells: crosstalk between NF-κB and PPAR-γ.
Zhang Y, Yang X, Bian F, Wu P, Xing S, Xu G, Li W, Chi J, Ouyang C, Zheng T, Wu D, Zhang Y, Li Y, Jin S
Journal of molecular and cellular cardiology 2014 Jul;72:85-94
Journal of molecular and cellular cardiology 2014 Jul;72:85-94
Effects of natural mineral-rich water consumption on the expression of sirtuin 1 and angiogenic factors in the erectile tissue of rats with fructose-induced metabolic syndrome.
Pereira CD, Severo M, Rafael L, Martins MJ, Neves D
Asian journal of andrology 2014 Jul-Aug;16(4):631-8
Asian journal of andrology 2014 Jul-Aug;16(4):631-8
Ruthenium(II) polypyridyl complexes: cellular uptake, cell image and apoptosis of HeLa cancer cells induced by double targets.
Yu Q, Liu Y, Xu L, Zheng C, Le F, Qin X, Liu Y, Liu J
European journal of medicinal chemistry 2014 Jul 23;82:82-95
European journal of medicinal chemistry 2014 Jul 23;82:82-95
Lactobacillus casei reduces susceptibility to type 2 diabetes via microbiota-mediated body chloride ion influx.
Zhang Y, Guo X, Guo J, He Q, Li H, Song Y, Zhang H
Scientific reports 2014 Jul 18;4:5654
Scientific reports 2014 Jul 18;4:5654
Nanoscale chromatin profiling of gastric adenocarcinoma reveals cancer-associated cryptic promoters and somatically acquired regulatory elements.
Muratani M, Deng N, Ooi WF, Lin SJ, Xing M, Xu C, Qamra A, Tay ST, Malik S, Wu J, Lee MH, Zhang S, Tan LL, Chua H, Wong WK, Ong HS, Ooi LL, Chow PK, Chan WH, Soo KC, Goh LK, Rozen S, Teh BT, Yu Q, Ng HH, Tan P
Nature communications 2014 Jul 10;5:4361
Nature communications 2014 Jul 10;5:4361
Chondroprotective effects and multi-target mechanisms of Icariin in IL-1 beta-induced human SW 1353 chondrosarcoma cells and a rat osteoarthritis model.
Zeng L, Wang W, Rong XF, Zhong Y, Jia P, Zhou GQ, Li RH
International immunopharmacology 2014 Jan;18(1):175-81
International immunopharmacology 2014 Jan;18(1):175-81
Protection of ischemic post conditioning against transient focal ischemia-induced brain damage is associated with inhibition of neuroinflammation via modulation of TLR2 and TLR4 pathways.
Wang Y, Ge P, Yang L, Wu C, Zha H, Luo T, Zhu Y
Journal of neuroinflammation 2014 Jan 24;11:15
Journal of neuroinflammation 2014 Jan 24;11:15
Expression of SPRR3 is associated with tumor cell proliferation and invasion in glioblastoma multiforme.
Liu Q, Zhang C, Ma G, Zhang Q
Oncology letters 2014 Feb;7(2):427-432
Oncology letters 2014 Feb;7(2):427-432
MiR-451 increases radiosensitivity of nasopharyngeal carcinoma cells by targeting ras-related protein 14 (RAB14).
Zhang T, Sun Q, Liu T, Chen J, Du S, Ren C, Liao G, Yuan Y
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2014 Dec;35(12):12593-9
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2014 Dec;35(12):12593-9
Fluoride affects calcium homeostasis and osteogenic transcription factor expressions through L-type calcium channels in osteoblast cell line.
Duan XQ, Zhao ZT, Zhang XY, Wang Y, Wang H, Liu DW, Li GS, Jing L
Biological trace element research 2014 Dec;162(1-3):219-26
Biological trace element research 2014 Dec;162(1-3):219-26
MicroRNA-15b promotes neurogenesis and inhibits neural progenitor proliferation by directly repressing TET3 during early neocortical development.
Lv X, Jiang H, Liu Y, Lei X, Jiao J
EMBO reports 2014 Dec;15(12):1305-14
EMBO reports 2014 Dec;15(12):1305-14
Lentiviral vector-mediated RBM5 overexpression downregulates EGFR expression in human non-small cell lung cancer cells.
Su Z, Yin J, Zhao L, Li R, Liang H, Zhang J, Wang K
World journal of surgical oncology 2014 Dec 2;12:367
World journal of surgical oncology 2014 Dec 2;12:367
Blocking autophagy enhanced cytotoxicity induced by recombinant human arginase in triple-negative breast cancer cells.
Wang Z, Shi X, Li Y, Fan J, Zeng X, Xian Z, Wang Z, Sun Y, Wang S, Song P, Zhao S, Hu H, Ju D
Cell death & disease 2014 Dec 11;5:e1563
Cell death & disease 2014 Dec 11;5:e1563
The expression level of TRAF1 in human gastric mucosa is related to virulence genotypes of Helicobacter pylori.
Wang F, Bu G, Feng Q, Liu Z, Xu C, Shen S, Yuan Y
Scandinavian journal of gastroenterology 2014 Aug;49(8):925-32
Scandinavian journal of gastroenterology 2014 Aug;49(8):925-32
Reversal of multidrug resistance in vitro and in vivo by 5-N-formylardeemin, a new ardeemin derivative.
Zheng X, Li D, Zhao C, Wang Q, Song H, Qin Y, Liao L, Zhang L, Lin Y, Wang X
Apoptosis : an international journal on programmed cell death 2014 Aug;19(8):1293-300
Apoptosis : an international journal on programmed cell death 2014 Aug;19(8):1293-300
oxLDL/β2GPI/anti-β2GPI complex induced macrophage differentiation to foam cell involving TLR4/NF-kappa B signal transduction pathway.
Xu Y, Kong X, Zhou H, Zhang X, Liu J, Yan J, Xie H, Xie Y
Thrombosis research 2014 Aug;134(2):384-92
Thrombosis research 2014 Aug;134(2):384-92
Anthocyanin-rich fractions from red raspberries attenuate inflammation in both RAW264.7 macrophages and a mouse model of colitis.
Li L, Wang L, Wu Z, Yao L, Wu Y, Huang L, Liu K, Zhou X, Gou D
Scientific reports 2014 Aug 29;4:6234
Scientific reports 2014 Aug 29;4:6234
The crucial role of Atg5 in cortical neurogenesis during early brain development.
Lv X, Jiang H, Li B, Liang Q, Wang S, Zhao Q, Jiao J
Scientific reports 2014 Aug 11;4:6010
Scientific reports 2014 Aug 11;4:6010
si-DNMT1 restore tumor suppressor genes expression through the reversal of DNA hypermethylation in cholangiocarcinoma.
Xiang J, Luo F, Chen Y, Zhu F, Wang J
Clinics and research in hepatology and gastroenterology 2014 Apr;38(2):181-9
Clinics and research in hepatology and gastroenterology 2014 Apr;38(2):181-9
NLRP3 deficiency ameliorates neurovascular damage in experimental ischemic stroke.
Yang F, Wang Z, Wei X, Han H, Meng X, Zhang Y, Shi W, Li F, Xin T, Pang Q, Yi F
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2014 Apr;34(4):660-7
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2014 Apr;34(4):660-7
A synergic role of caspase-6 and caspase-3 in Tau truncation at D421 induced by H2O 2.
Zhao H, Zhao W, Lok K, Wang Z, Yin M
Cellular and molecular neurobiology 2014 Apr;34(3):369-78
Cellular and molecular neurobiology 2014 Apr;34(3):369-78
miR-200c inhibits metastasis of breast cancer cells by targeting HMGB1.
Chang BP, Wang DS, Xing JW, Yang SH, Chu Q, Yu SY
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 2014 Apr;34(2):201-206
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 2014 Apr;34(2):201-206
Epigallocatechin-3-gallate inhibits TF and TNF-α expression induced by the anti-β2GPI/β2GPI complex in human THP-1 cells.
Wang T, Zhou H, Xie H, Mu Y, Xu Y, Liu J, Zhang X
International journal of molecular medicine 2014 Apr;33(4):994-1002
International journal of molecular medicine 2014 Apr;33(4):994-1002
Association analysis of UGT1A genotype and haplotype with SN-38 glucuronidation in human livers.
Wang H, Bian T, Jin T, Chen Y, Lin A, Chen C
Pharmacogenomics 2014 Apr;15(6):785-98
Pharmacogenomics 2014 Apr;15(6):785-98
Activation of spinal glucagon-like peptide-1 receptors specifically suppresses pain hypersensitivity.
Gong N, Xiao Q, Zhu B, Zhang CY, Wang YC, Fan H, Ma AN, Wang YX
The Journal of neuroscience : the official journal of the Society for Neuroscience 2014 Apr 9;34(15):5322-34
The Journal of neuroscience : the official journal of the Society for Neuroscience 2014 Apr 9;34(15):5322-34
Ezh2 regulates adult hippocampal neurogenesis and memory.
Zhang J, Ji F, Liu Y, Lei X, Li H, Ji G, Yuan Z, Jiao J
The Journal of neuroscience : the official journal of the Society for Neuroscience 2014 Apr 9;34(15):5184-99
The Journal of neuroscience : the official journal of the Society for Neuroscience 2014 Apr 9;34(15):5184-99
Ubiquitin B in cervical cancer: critical for the maintenance of cancer stem-like cell characters.
Tian Y, Ding W, Wang Y, Ji T, Sun S, Mo Q, Chen P, Fang Y, Liu J, Wang B, Zhou J, Ma D, Wu P
PloS one 2013;8(12):e84457
PloS one 2013;8(12):e84457
Simvastatin alleviates hyperpermeability of glomerular endothelial cells in early-stage diabetic nephropathy by inhibition of RhoA/ROCK1.
Peng H, Luo P, Li Y, Wang C, Liu X, Ye Z, Li C, Lou T
PloS one 2013;8(11):e80009
PloS one 2013;8(11):e80009
NOD2 deficiency protects against cardiac remodeling after myocardial infarction in mice.
Li X, Li F, Chu Y, Wang X, Zhang H, Hu Y, Zhang Y, Wang Z, Wei X, Jian W, Zhang X, Yi F
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2013;32(6):1857-66
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2013;32(6):1857-66
Scutellarin attenuates hypertension-induced expression of brain Toll-like receptor 4/nuclear factor kappa B.
Chen X, Shi X, Zhang X, Lei H, Long S, Su H, Pei Z, Huang R
Mediators of inflammation 2013;2013:432623
Mediators of inflammation 2013;2013:432623
Anti-β2GPI/β2GPI stimulates activation of THP-1 cells through TLR4/MD-2/MyD88 and NF-κB signaling pathways.
Zhou H, Sheng L, Wang H, Xie H, Mu Y, Wang T, Yan J
Thrombosis research 2013;132(6):742-9
Thrombosis research 2013;132(6):742-9
Overexpression of 4EBP1, p70S6K, Akt1 or Akt2 differentially promotes Coxsackievirus B3-induced apoptosis in HeLa cells.
Li X, Li Z, Zhou W, Xing X, Huang L, Tian L, Chen J, Chen C, Ma X, Yang Z
Cell death & disease 2013 Sep 12;4:e803-9
Cell death & disease 2013 Sep 12;4:e803-9
L-3-n-butylphthalide protects against vascular dementia via activation of the Akt kinase pathway.
Huai Y, Dong Y, Xu J, Meng N, Song C, Li W, Lv P
Neural regeneration research 2013 Jul 5;8(19):1733-42
Neural regeneration research 2013 Jul 5;8(19):1733-42
Specific deletion of Cdc42 does not affect meiotic spindle organization/migration and homologous chromosome segregation but disrupts polarity establishment and cytokinesis in mouse oocytes.
Wang ZB, Jiang ZZ, Zhang QH, Hu MW, Huang L, Ou XH, Guo L, Ouyang YC, Hou Y, Brakebusch C, Schatten H, Sun QY
Molecular biology of the cell 2013 Dec;24(24):3832-41
Molecular biology of the cell 2013 Dec;24(24):3832-41
Nucleoside analog inhibits microRNA-214 through targeting heat-shock factor 1 in human epithelial ovarian cancer.
Chen YF, Dong Z, Xia Y, Tang J, Peng L, Wang S, Lai D
Cancer science 2013 Dec;104(12):1683-9
Cancer science 2013 Dec;104(12):1683-9
Astragaloside IV attenuates inflammatory cytokines by inhibiting TLR4/NF-кB signaling pathway in isoproterenol-induced myocardial hypertrophy.
Yang J, Wang HX, Zhang YJ, Yang YH, Lu ML, Zhang J, Li ST, Zhang SP, Li G
Journal of ethnopharmacology 2013 Dec 12;150(3):1062-70
Journal of ethnopharmacology 2013 Dec 12;150(3):1062-70
Identification and analysis of glycogen synthase kinase 3 beta1 interactome.
Gao X, Wang JY, Gao LM, Yin XF, Liu L
Cell biology international 2013 Aug;37(8):768-79
Cell biology international 2013 Aug;37(8):768-79
Concurrent blockade of NF-κB and Akt pathways potentiates cisplatin's antitumor activity in vivo.
Sun H, Zheng X, Wang Q, Yan J, Li D, Zhou Y, Lin Y, Zhang L, Wang X
Anti-cancer drugs 2012 Nov;23(10):1039-46
Anti-cancer drugs 2012 Nov;23(10):1039-46
Anti-inflammatory mechanism of taurine against ischemic stroke is related to down-regulation of PARP and NF-κB.
Sun M, Zhao Y, Gu Y, Xu C
Amino acids 2012 May;42(5):1735-47
Amino acids 2012 May;42(5):1735-47
Surgery upregulates high mobility group box-1 and disrupts the blood-brain barrier causing cognitive dysfunction in aged rats.
He HJ, Wang Y, Le Y, Duan KM, Yan XB, Liao Q, Liao Y, Tong JB, Terrando N, Ouyang W
CNS neuroscience & therapeutics 2012 Dec;18(12):994-1002
CNS neuroscience & therapeutics 2012 Dec;18(12):994-1002
Regulation of fibroblast growth factor-2 expression and cell cycle progression by an endogenous antisense RNA.
Baguma-Nibasheka M, Macfarlane LA, Murphy PR
Genes 2012 Aug 16;3(3):505-20
Genes 2012 Aug 16;3(3):505-20
Rosuvastatin treatment activates JAK-STAT pathway and increases efficacy of allogeneic mesenchymal stem cell transplantation in infarcted hearts.
Xu H, Yang YJ, Qian HY, Tang YD, Wang H, Zhang Q
Circulation journal : official journal of the Japanese Circulation Society 2011;75(6):1476-85
Circulation journal : official journal of the Japanese Circulation Society 2011;75(6):1476-85
Involvement of IRAKs and TRAFs in anti-β₂GPI/β₂GPI-induced tissue factor expression in THP-1 cells.
Xu G, Wen H, Zhou H, Guo D, Zhou F, Chen D, Xie H, Wang T, Wang H
Thrombosis and haemostasis 2011 Dec;106(6):1158-69
Thrombosis and haemostasis 2011 Dec;106(6):1158-69
Atorvastatin prevents mesenchymal stem cells from hypoxia and serum-free injury through activating AMP-activated protein kinase.
Dong Q, Yang Y, Song L, Qian H, Xu Z
International journal of cardiology 2011 Dec 15;153(3):311-6
International journal of cardiology 2011 Dec 15;153(3):311-6
Lentiviral-mediated siRNA targeted against osteopontin suppresses the growth and metastasis of gastric cancer cells.
Wang ZM, Cui YH, Li W, Chen SY, Liu TS
Oncology reports 2011 Apr;25(4):997-1003
Oncology reports 2011 Apr;25(4):997-1003
Perturbation of survivin expression affects chromosome alignment and spindle checkpoint in mouse oocyte meiotic maturation.
Sun SC, Wei L, Li M, Lin SL, Xu BZ, Liang XW, Kim NH, Schatten H, Lu SS, Sun QY
Cell cycle (Georgetown, Tex.) 2009 Oct 15;8(20):3365-72
Cell cycle (Georgetown, Tex.) 2009 Oct 15;8(20):3365-72
[Effects of paclitaxel and gefitinib on the proliferation and cell cycle of human lung adenocarcinoma cell SPC-A1.].
Jia G, Zhang W, Zhou J, Zhu Z
Zhongguo fei ai za zhi = Chinese journal of lung cancer 2008 Jun 20;11(3):339-44
Zhongguo fei ai za zhi = Chinese journal of lung cancer 2008 Jun 20;11(3):339-44
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The beta actin antibody from Proteintech is a mouse monoclonal antibody to a fusion protein of human beta actin. This antibody recognizes human,monkey,mouse,rat,hamster,zebra fish antigen. The beta actin antibody has been validated for the following applications: ELISA, IHC, IF, IP, WB analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using ACTB antibody 66009-1-lg at 1:200 dilution and Rhodamine-labeled goat anti-mouse IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-beta actin (IP:66009-1-Ig, 3ug; Detection:66009-1-Ig 1:10000) with HeLa cells lysate 3100ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 66009-1-Ig(Actin antibody) at dilution of 1:500 (under 40x lens)
- Sample type
- tissue
