Antibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [1]
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Validation data
Reference
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- Product number
- 12895-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12895-1-AP, RRID:AB_2086291
- Product name
- CUL1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated CUL1 antibody (Cat. #12895-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, IP, WB, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Cardioprotective effect of MLN4924 on ameliorating autophagic flux impairment in myocardial ischemia-reperfusion injury by Sirt1.
The potential oncogenic and MLN4924-resistant effects of CSN5 on cervical cancer cells.
Let-7i-5p Regulation of Cell Morphology and Migration Through Distinct Signaling Pathways in Normal and Pathogenic Urethral Fibroblasts.
Nedd8-activating enzyme inhibitor MLN4924 (Pevonedistat), inhibits miR-1303 to suppress human breast cancer cell proliferation via targeting p27Kip1.
Gossypol inhibits cullin neddylation by targeting SAG-CUL5 and RBX1-CUL1 complexes.
Inhibition of neddylation causes meiotic arrest in mouse oocyte.
The ubiquitin ligase SCFFBXW7α promotes GATA3 degradation.
Cullin-3-KCTD10-mediated CEP97 degradation promotes primary cilium formation.
Zhang J, Cui J, Zhao F, Yang L, Xu X, Shi Y, Wei B
Redox biology 2021 Oct;46:102114
Redox biology 2021 Oct;46:102114
The potential oncogenic and MLN4924-resistant effects of CSN5 on cervical cancer cells.
Zhang H, He P, Zhou Q, Lu Y, Lu B
Cancer cell international 2021 Jul 12;21(1):369
Cancer cell international 2021 Jul 12;21(1):369
Let-7i-5p Regulation of Cell Morphology and Migration Through Distinct Signaling Pathways in Normal and Pathogenic Urethral Fibroblasts.
Zhang K, Yang R, Chen J, Qi E, Zhou S, Wang Y, Fu Q, Chen R, Fang X
Frontiers in bioengineering and biotechnology 2020;8:428
Frontiers in bioengineering and biotechnology 2020;8:428
Nedd8-activating enzyme inhibitor MLN4924 (Pevonedistat), inhibits miR-1303 to suppress human breast cancer cell proliferation via targeting p27Kip1.
Chen Y, Du M, Yusuying S, Liu W, Tan Y, Xie P
Experimental cell research 2020 Jul 15;392(2):112038
Experimental cell research 2020 Jul 15;392(2):112038
Gossypol inhibits cullin neddylation by targeting SAG-CUL5 and RBX1-CUL1 complexes.
Yu Q, Hu Z, Shen Y, Jiang Y, Pan P, Hou T, Pan ZQ, Huang J, Sun Y
Neoplasia (New York, N.Y.) 2020 Apr;22(4):179-191
Neoplasia (New York, N.Y.) 2020 Apr;22(4):179-191
Inhibition of neddylation causes meiotic arrest in mouse oocyte.
Yang M, Jin Y, Fan S, Liang X, Jia J, Tan Z, Huang T, Li Y, Ma T, Li M
Cell cycle (Georgetown, Tex.) 2019 Jun;18(11):1254-1267
Cell cycle (Georgetown, Tex.) 2019 Jun;18(11):1254-1267
The ubiquitin ligase SCFFBXW7α promotes GATA3 degradation.
Song N, Cao C, Tang Y, Bi L, Jiang Y, Zhou Y, Song X, Liu L, Ge W
Journal of cellular physiology 2018 Mar;233(3):2366-2377
Journal of cellular physiology 2018 Mar;233(3):2366-2377
Cullin-3-KCTD10-mediated CEP97 degradation promotes primary cilium formation.
Nagai T, Mukoyama S, Kagiwada H, Goshima N, Mizuno K
Journal of cell science 2018 Dec 12;131(24)
Journal of cell science 2018 Dec 12;131(24)
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- BxPC-3 cells were subjected to SDS PAGE followed by western blot with 12895-1-AP(CUL1 antibody) at dilution of 1:400
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-CUL1 (IP:12895-1-AP, 3ug; Detection:12895-1-AP 1:300) with HeLa cells lysate 2000ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The CUL1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human CUL1. This antibody recognizes human,mouse,rat antigen. The CUL1 antibody has been validated for the following applications: ELISA, WB, IHC, IP analysis.