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Protein structure
CENPA
Centromere protein ACenH3, CENP-A
Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. This gene encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. Centromere protein A is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. The protein is a replication-independent histone that is a member of the histone H3 family. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Nov 2015]
Top validated antibodies |
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| GeneTex |  GTX13939 |
12 references | Monoclonal |
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| LSBio | LS-C448339 |
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| Invitrogen Antibodies | MA1-20832 |
1 references | Monoclonal |
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| Enzo Life Sciences | ADI-KAM-CC006-E |
1 references | Monoclonal |
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| Cell Signaling Technology, Inc | 2187 |
1 references | Polyclonal |
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