FNab07536

antibody from FineTest Biotech

Targeting: RUNX2 AML3, CBFA1, CCD, CCD1, PEBP2A1, PEBP2aA1

Western blot

ELISA

Antibody data

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Validation data

Product number: FNab07536 - Provider product page
Provider: FineTest Biotech
Product name: RUNX2 antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: Transcription factor involved in osteoblastic differentiation and skeletal morphogenesis. Essential for the maturation of osteoblasts and both intramembranous and endochondral ossification. CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, osteocalcin, osteopontin, bone sialoprotein, alpha 1(I) collagen, LCK, IL-3 and GM-CSF promoters. In osteoblasts, supports transcription activation: synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element(OCFRE)(By similarity). Inhibits KAT6B-dependent transcriptional activation.
Reactivity: Human, Mouse
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: runt-related transcription factor 2
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

RUNX2 protein structure - FNab07536 shown in red.