Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- A02033 - Provider product page
- Provider
- Boster Biological Technology
- Product name
- Anti-MART-1 MLANA Antibody
- Antibody type
- Polyclonal
- Description
- Polyclonal antibody for MART 1/MLANA detection. Host: Rabbit.Size: 100μl. Tested applications: IHC. Reactive species: Human. MART 1/MLANA information: Molecular Weight: 13157 MW; Subcellular Localization: Endoplasmic reticulum membrane; Single-pass type III membrane protein. Golgi apparatus. Golgi apparatus, trans-Golgi network membrane. Melanosome. Also found in small vesicles and tubules dispersed over the entire cytoplasm. A small fraction of the protein is inserted into the membrane in an inverted orientation. Inversion of membrane topology results in the relocalization of the protein from a predominant Golgi/post- Golgi area to the endoplasmic reticulum. Melanoma cells expressing the protein with an inverted membrane topology are more effectively recognized by specific cytolytic T-lymphocytes than those expressing the protein in its native membrane orientation; Tissue Specificity: Expression is restricted to melanoma and melanocyte cell lines and retina.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Vial size
- 100μl
- Concentration
- 0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
- Storage
- Store at -20°C for one year, at 4°C for one month. We suggest the antibody be aliquoted into small vials and stored frozen at -20°C upon receiving. Avoid repeated freezing and thawing.
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Supportive validation
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- Boster Biological Technology (provider)
- Main image
- Experimental details
- Western blot analysis of extracts from NIH/3T3 cells, using MART-1 antibody A02033.
- Additional image