Antibody data
- Antibody Data
- Antigen structure
- References [6]
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- Validations
- Western blot [3]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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- Product number
- ABIN151911 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Checkpoint Kinase 1 (CHEK1) (AA 250-300) antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- AA 250-300
- Isotype
- IgG
- Vial size
- 100 μL
- Storage
- Store at 4°C. Do not freeze.
- Handling
- Do not freeze.
Submitted references Serine/Threonine Kinase CHEK1-Dependent Transcriptional Regulation of RAD54L Promotes Proliferation and Radio Resistance in Glioblastoma.
Overcoming platinum resistance in preclinical models of ovarian cancer using the neddylation inhibitor MLN4924.
Degradation of p12 subunit by CRL4Cdt2 E3 ligase inhibits fork progression after DNA damage.
CHK1 targets spleen tyrosine kinase (L) for proteolysis in hepatocellular carcinoma.
The effect of the intra-S-phase checkpoint on origins of replication in human cells.
Involvement of the ATR- and ATM-dependent checkpoint responses in cell cycle arrest evoked by pierisin-1.
Bai X, Wang J, Huo L, Xie Y, Xie W, Xu G, Wang M
Translational oncology 2018 Feb;11(1):140-146
Translational oncology 2018 Feb;11(1):140-146
Overcoming platinum resistance in preclinical models of ovarian cancer using the neddylation inhibitor MLN4924.
Jazaeri AA, Shibata E, Park J, Bryant JL, Conaway MR, Modesitt SC, Smith PG, Milhollen MA, Berger AJ, Dutta A
Molecular cancer therapeutics 2013 Oct;12(10):1958-67
Molecular cancer therapeutics 2013 Oct;12(10):1958-67
Degradation of p12 subunit by CRL4Cdt2 E3 ligase inhibits fork progression after DNA damage.
Terai K, Shibata E, Abbas T, Dutta A
The Journal of biological chemistry 2013 Oct 18;288(42):30509-14
The Journal of biological chemistry 2013 Oct 18;288(42):30509-14
CHK1 targets spleen tyrosine kinase (L) for proteolysis in hepatocellular carcinoma.
Hong J, Hu K, Yuan Y, Sang Y, Bu Q, Chen G, Yang L, Li B, Huang P, Chen D, Liang Y, Zhang R, Pan J, Zeng YX, Kang T
The Journal of clinical investigation 2012 Jun;122(6):2165-75
The Journal of clinical investigation 2012 Jun;122(6):2165-75
The effect of the intra-S-phase checkpoint on origins of replication in human cells.
Karnani N, Dutta A
Genes & development 2011 Mar 15;25(6):621-33
Genes & development 2011 Mar 15;25(6):621-33
Involvement of the ATR- and ATM-dependent checkpoint responses in cell cycle arrest evoked by pierisin-1.
Shiotani B, Kobayashi M, Watanabe M, Yamamoto K, Sugimura T, Wakabayashi K
Molecular cancer research : MCR 2006 Feb;4(2):125-33
Molecular cancer research : MCR 2006 Feb;4(2):125-33
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Supportive validation
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