BBA24

antibody from R&D Systems

Targeting: SELL CD62L, hLHRc, LAM-1, LAM1, Leu-8, LNHR, LSEL, Lyam-1, LYAM1, PLNHR

ELISA (Data presented on provider website)

Flow cytometry (Data presented on provider website)

Antibody Data

Product number

BBA24

Provider

R&D Systems

Product name

Human L-Selectin/CD62L Antibody

Antibody type

Monoclonal

Description

Protein A or G purified from hybridoma culture supernatant. Binds to CHO cells expressing the human L-Selectin/CD62L protein. It does not recognize CHO cells expressing either the human E-Selectin or human P-Selectin.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

4G8

Vial size

200 ug

Concentration

LYOPH

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

References

Submitted references

Augmentation of Human Monocyte Responses to Lipopolysaccharide by the Protein S and Mer/Tyro3 Receptor Tyrosine Kinase Axis.

Barth ND, Marwick JA, Heeb MJ, Gale AJ, Rossi AG, Dransfield I
Journal of immunology (Baltimore, Md. : 1950) 2018 Nov 1;201(9):2602-2611

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NFKB1 regulates human NK cell maturation and effector functions.

Lougaris V, Patrizi O, Baronio M, Tabellini G, Tampella G, Damiati E, Frede N, van der Meer JWM, Fliegauf M, Grimbacher B, Parolini S, Plebani A
Clinical immunology (Orlando, Fla.) 2017 Feb;175:99-108

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Regulatory T cells inhibit CD34+ cell differentiation into NK cells by blocking their proliferation.

Pedroza-Pacheco I, Shah D, Domogala A, Luevano M, Blundell M, Jackson N, Thrasher A, Madrigal A, Saudemont A
Scientific reports 2016 Feb 26;6:22097

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Facile supermolecular aptamer inhibitors of L-selectin.

Chang EK, Eckert MA, Ali MM, Riazifar H, Pone EJ, Liu L, Zhao W
PloS one 2015;10(3):e0123034

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Attenuated, oncolytic, but not wild-type measles virus infection has pleiotropic effects on human neutrophil function.

Zhang Y, Patel B, Dey A, Ghorani E, Rai L, Elham M, Castleton AZ, Fielding AK
Journal of immunology (Baltimore, Md. : 1950) 2012 Feb 1;188(3):1002-10

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Aberration of CCR7 CD8 memory T cells from patients with systemic lupus erythematosus: an inducer of T helper type 2 bias of CD4 T cells.

Sen Y, Chunsong H, Baojun H, Linjie Z, Qun L, San J, Qiuping Z, Junyan L, Zhang X, Jinquan T
Immunology 2004 Jun;112(2):274-89

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The soluble form of IL-1 receptor accessory protein enhances the ability of soluble type II IL-1 receptor to inhibit IL-1 action.

Smith DE, Hanna R, Della Friend, Moore H, Chen H, Farese AM, MacVittie TJ, Virca GD, Sims JE
Immunity 2003 Jan;18(1):87-96

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The soluble form of IL-1 receptor accessory protein enhances the ability of soluble type II IL-1 receptor to inhibit IL-1 action.

Smith DE, Hanna R, Della Friend, Moore H, Chen H, Farese AM, MacVittie TJ, Virca GD, Sims JE
Immunity 2003 Jan;18(1):87-96