Tissue expression
Cell line expression
Protein structure
TSC2
TSC complex subunit 2LAM, PPP1R160, TSC4, tuberin
Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Invitrogen Antibodies | ![]() |
6 references | Monoclonal |
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LSBio | ![]() |
Polyclonal |
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Proteintech Group | ![]() |
8 references | Polyclonal |
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Cell Signaling Technology, Inc | ![]() |
6 references | Monoclonal |
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Abnova Corporation | ![]() |
2 references | Polyclonal |
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