BS7860

antibody from Bioworld Technology, Inc
Targeting: CD22 SIGLEC-2, SIGLEC2
Provider product page for BS7860
Western blot
Immunohistochemistry

Antibody data

Product number
BS7860 - Provider product page
Provider
Bioworld Technology, Inc
Product name
CD22 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human CD22.
Description
The B lymphocyte specific CD22 antigen, also designated B-lymphocyte cell adhesion molecule (BLCAM), sialic acid-binding Ig-like lectin 2 (Siglec-2) and Leu-14, is a type I integral membrane glycoprotein, structurally similar to other cell adhesion molecules (CAMs), which acts as a regulator of B cell signaling. CD22 is expressed as both a cytoplasmic and membrane protein during discrete stages of B cell lymphocyte differentiation. The cytoplasmic form of CD22, expressed early in B cell development, is a useful marker for acute lymphocytic leukemia. The membrane form of CD22 is expressed in mature B cells prior to their differentiation into plasma cells. Alternative splicing results in two different isoforms, CD22Ï« and CD22ÉÇ. The CD22ÉÇ monomer is the principally occurring isoform but CD22 also appears as a heterodimer of CD22ÉÇ and the shorter isoform, CD22Ï«.
Reactivity
Human, Mouse
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
CD22 protein structure - BS7860 shown in red.