Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Flow cytometry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 310943 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#310943, RRID:AB_2566465
- Product name
- Brilliant Violet 711™ anti-human CD69
- Antibody type
- Monoclonal
- Antigen
- Other
- Description
- CD69 is a 27-33 kD type II transmembrane protein also known as activation inducer molecule (AIM), very early activation antigen (VEA), and MLR3. It is a member of the C-type lectin family, expressed as a disulfide-linked homodimer. Other members of this receptor family include NKG2, NKR-P1 CD94, and Ly49. CD69 is transiently expressed on activated leukocytes including T cells, thymocytes, B cells, NK cells, neutrophils, and eosinophils. CD69 is constitutively expressed by a subset of medullary mature thymocytes, platelets, mantle B cells, and certain CD4+ T cells in germinal centers of normal lymph nodes. CD69 is involved in early events of lymphocyte, monocyte, and platelet activation, and has a functional role in redirected lysis mediated by activated NK cells.
- Reactivity
- Human, Porcine
- Host
- Mouse
- Conjugate
- Red dye
- Antibody clone number
- FN50
- Vial size
- 25 tests
- Storage
- 2°C-8°C
- Handling
- Ambient RT
No comments: Submit comment
Supportive validation
- Submitted by
- BioLegend (provider)
- Main image
- Experimental details
- PMA + ionomycin-stimulated (six hours) human peripheral blood lymphocytes were stained with CD69 (clone FN50) Brilliant Violet 711™ (filled histogram) or mouse IgG1, κ ™ isotype control (open histogram).
- Conjugate
- Red dye