Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Flow cytometry [1]
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Validation data
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- Product number
- 310902 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#310902, RRID:AB_314837
- Product name
- Purified anti-human CD69
- Antibody type
- Monoclonal
- Antigen
- CD69
- Description
- CD69 is a 27-33 kD type II transmembrane protein also known as activation inducer molecule (AIM), very early activation antigen (VEA), and MLR3. It is a member of the C-type lectin family, expressed as a disulfide-linked homodimer. Other members of this receptor family include NKG2, NKR-P1 CD94, and Ly49. CD69 is transiently expressed on activated leukocytes including T cells, thymocytes, B cells, NK cells, neutrophils, and eosinophils. CD69 is constitutively expressed by a subset of medullary mature thymocytes, platelets, mantle B cells, and certain CD4+ T cells in germinal centers of normal lymph nodes. CD69 is involved in early events of lymphocyte, monocyte, and platelet activation, and has a functional role in redirected lysis mediated by activated NK cells.
- Reactivity
- Human, Simian
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µg
- Concentration
- 0.5 mg/ml
- Storage
- The antibody solution should be stored undiluted at 4°C.
Submitted references Establishment of an immunoglobulin m antibody-forming cell response model for characterizing immunotoxicity in primary human B cells.
Differential expression of the human CD8beta splice variants and regulation of the M-2 isoform by ubiquitination.
Lu H, Crawford RB, North CM, Kaplan BL, Kaminski NE
Toxicological sciences : an official journal of the Society of Toxicology 2009 Dec;112(2):363-73
Toxicological sciences : an official journal of the Society of Toxicology 2009 Dec;112(2):363-73
Differential expression of the human CD8beta splice variants and regulation of the M-2 isoform by ubiquitination.
Thakral D, Dobbins J, Devine L, Kavathas PB
Journal of immunology (Baltimore, Md. : 1950) 2008 Jun 1;180(11):7431-42
Journal of immunology (Baltimore, Md. : 1950) 2008 Jun 1;180(11):7431-42
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Supportive validation
- Submitted by
- BioLegend (provider)
- Main image
- Experimental details
- PHA-activated human peripheral blood lymphocytes stained with purified FN50, followed by anti-mouse IgGs FITC
- Conjugate
- Unconjugated