Tissue expression
Cell line expression
Protein structure
PCNA
Proliferating cell nuclear antigenThe protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008]
Top validated antibodies |
|||||
Novus Biologicals | ![]() |
32 references | Monoclonal |
|
|
Proteintech Group | ![]() |
878 references | Polyclonal |
|
|
Invitrogen Antibodies | ![]() |
213 references | Monoclonal |
|
|
GeneTex | ![]() |
17 references | Monoclonal |
|
|
NSJ Bioreagents | ![]() |
8 references | Monoclonal |
|