FNab00810

antibody from FineTest Biotech

Targeting: BAX BCL2L4

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Validation data

Product number: FNab00810 - Provider product page
Provider: FineTest Biotech
Product name: BAX antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: BAX, also named as BCL2L4, is a pro-apoptotic member of the Bcl-2 protein family, which plays a pivotal role in controlling cell life and death. Bax largely localizes to the cytoplasm of healthy cells, but accumulates on the outer mitochondrial membrane upon apoptosis induction(PMID: 9108035). BAX can commit a cell to apoptosis by translocation from the cytosol to the mitochondria and permeabilization of the outer mitochondrial membrane, which leads to the release of cytochrome c from mitochondria(PMID: 21763611). The expression of BAX is upregulated by the tumor suppressor protein p53, and BAX has been shown to be involved in p53-mediated apoptosis(PMID: 8183579).
Reactivity: Human, Mouse, Rat, Rabbit, Sheep
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: BCL2-associated X protein
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

BAX protein structure - FNab00810 shown in red.