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- Product number
- 60267-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- BAX antibody
- Antibody type
- Monoclonal
- Description
- BAX antibody (Cat. #60267-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 4G5E8
- Vial size
- 20ul, 150ul
Submitted references Attenuation of hepatic ischemia‑reperfusion injury by adipose stem cell‑derived exosome treatment via ERK1/2 and GSK‑3β signaling pathways.
CTRP1 Attenuates Cerebral Ischemia/Reperfusion Injury via the PERK Signaling Pathway.
NLGN3 Upregulates Expression of ADAM10 to Promote the Cleavage of NLGN3 via Activating the LYN Pathway in Human Gliomas.
Cold-Induced RNA-Binding Protein Promotes Glucose Metabolism and Reduces Apoptosis by Increasing AKT Phosphorylation in Mouse Skeletal Muscle Under Acute Cold Exposure.
Cannabisin D from Sinomenium Acutum Inhibits Proliferation and Migration of Glioblastoma Cells through MAPKs Signaling.
Expression of Ubiquitin-specific protease 7 in oral squamous cell carcinoma promotes tumor cell proliferation and invasion.
Erteng-Sanjie Capsule Enhances Chemosensitivity of 5-Fluorouracil in Tumor-Bearing Nude Mice with Gastric Cancer by Inhibiting Notch1/Hes1 Signaling Pathway.
Study on Protection of Human Umbilical Vein Endothelial Cells from Amiodarone-Induced Damage by Intermedin through Activation of Wnt/β-Catenin Signaling Pathway.
Tetrandrine Ameliorates Myocardial Ischemia Reperfusion Injury through miR-202-5p/TRPV2.
Farrerol Enhances Nrf2-Mediated Defense Mechanisms against Hydrogen Peroxide-Induced Oxidative Damage in Human Retinal Pigment Epithelial Cells by Activating Akt and MAPK.
Wenxin Granules Regulate Endoplasmic Reticulum Stress Unfolded Protein Response and Improve Ventricular Remodeling on Rats with Myocardial Infarction.
Bioactive Peptide F2d Isolated from Rice Residue Exerts Antioxidant Effects via Nrf2 Signaling Pathway.
Luteolin Improves Cyclophosphamide-Induced Cystitis through TXNIP/NLRP3 and NF-κB Pathways.
Qingda granule exerts neuroprotective effects against ischemia/reperfusion-induced cerebral injury via lncRNA GAS5/miR-137 signaling pathway.
Hyperbaric Oxygen Therapy Attenuates Burn-Induced Denervated Muscle Atrophy.
Therapeutic Efficacy of Carbon Ion Irradiation Enhanced by 11-MUA-Capped Gold Nanoparticles: An in vitro and in vivo Study.
Inhibition of mu-opioid receptor suppresses proliferation of hepatocellular carcinoma cells via CD147-p53-MAPK cascade signaling pathway.
The COL11A1/Akt/CREB signaling axis enables mitochondrial-mediated apoptotic evasion to promote chemoresistance in pancreatic cancer cells through modulating BAX/BCL-2 function.
Elevated HNF1A expression promotes radiation-resistance via driving PI3K/AKT signaling pathway in esophageal squamous cell carcinoma cells.
MicroRNA-455-5p Contributes to Cholangiocarcinoma Growth and Mediates Galangin's Anti-Tumor Effects.
Kaempferol Ameliorates the Inhibitory Activity of Dexamethasone in the Osteogenesis of MC3T3-E1 Cells by JNK and p38-MAPK Pathways.
miR-25 Regulates Gastric Cancer Cell Growth and Apoptosis by Targeting EGR2.
Elevated Serum FGG Levels Prognosticate and Promote the Disease Progression in Prostate Cancer.
Proteomic analysis reveals ginsenoside Rb1 attenuates myocardial ischemia/reperfusion injury through inhibiting ROS production from mitochondrial complex I.
Endoplasmic reticulum stress is involved in retinal injury induced by repeated transient spikes of intraocular pressure.
Effects of Ganfule capsule on microbial and metabolic profiles in anti-hepatocellular carcinoma.
Hydroxychloroquine alleviates the neurotoxicity induced by anti-ribosomal P antibodies.
Oridonin prevents oxidative stress-induced endothelial injury via promoting Nrf-2 pathway in ischaemic stroke.
Inhibition of autophagy with Chloroquine enhanced apoptosis induced by 5-aminolevulinic acid-photodynamic therapy in secondary hyperparathyroidism primary cells and organoids.
EphA2 inhibits SRA01/04 cells apoptosis by suppressing autophagy via activating PI3K/Akt/mTOR pathway.
Aronia melanocarpa polysaccharide ameliorates inflammation and aging in mice by modulating the AMPK/SIRT1/NF-κB signaling pathway and gut microbiota.
Mechanism of a new photosensitizer (TBZPy) in the treatment of high-risk human papillomavirus-related diseases.
Bioactive substances in the stratum corneum of the epidermis found as indicators of skin damage due to sun exposure.
LncDACH1 promotes mitochondrial oxidative stress of cardiomyocytes by interacting with sirtuin3 and aggravates diabetic cardiomyopathy.
m6A-mediated upregulation of AC008 promotes osteoarthritis progression through the miR-328-3p‒AQP1/ANKH axis.
Abnormally elevated ubiquilin‑1 expression in breast cancer regulates metastasis and stemness via AKT signaling.
Virtual screening based identification of miltefosine and octenidine as inhibitors of heat shock protein 90.
SC66 inhibits the proliferation and induces apoptosis of human bladder cancer cells by targeting the AKT/β-catenin pathway.
Metformin attenuates H(2)O(2)-induced osteoblast apoptosis by regulating SIRT3 via the PI3K/AKT pathway.
The inhibitory effect Polygonum Cillinerve polysaccharide on transmissible gastroenteritis virus of swine.
Alnustone inhibits the growth of hepatocellular carcinoma via ROS- mediated PI3K/Akt/mTOR/p70S6K axis.
CCAAT/Enhancer-Binding Protein Homologous Protein (CHOP) Deficiency Attenuates Heatstroke-Induced Intestinal Injury.
Inhibition of Ras protein activator like 2 produces antitumor effects in gastric cancer via the suppression of YAP1 activation.
Morphine promotes the malignant biological behavior of non-small cell lung cancer cells through the MOR/Src/mTOR pathway.
Prodrug polymeric micelles integrating cancer-associated fibroblasts deactivation and synergistic chemotherapy for gastric cancer.
The Effects of Flavonoid Apigenin on Male Reproductive Health: Inhibition of Spermatogonial Proliferation through Downregulation of Prmt7/Akt3 Pathway.
Sodium cantharidate induces Apoptosis in breast cancer cells by regulating energy metabolism via the protein phosphatase 5-p53 axis.
Methylation gene KCNC1 is associated with overall survival in patients with seminoma.
Toxicological and physiological effects of successive exposure to ochratoxin A at food regulatory limits.
Dual-Targeting Antiproliferation Hybrids Derived from 1-Deoxynojirimycin and Kaempferol Induce MCF-7 Cell Apoptosis through the Mitochondria-Mediated Pathway.
Upregulation of PPPDE1 contributes to anorectal malformations via the mitochondrial apoptosis pathway during hindgut development in rats.
Graphene oxide exacerbates dextran sodium sulfate-induced colitis via ROS/AMPK/p53 signaling to mediate apoptosis.
Iguratimod-encapsulating PLGA-NPs induce human multiple myeloma cell death via reactive oxygen species and Caspase-dependent signalling.
Sparstolonin B exerts beneficial effects on prostate cancer by acting on the reactive oxygen species-mediated PI3K/AKT pathway.
O-GlcNAc / Akt pathway regulates glucose metabolism and reduces apoptosis in liver of piglets with acute cold stress.
Effects of β-Asarone on Ischemic Stroke in Middle Cerebral Artery Occlusion Rats by an Nrf2-Antioxidant Response Elements (ARE) Pathway-Dependent Mechanism.
YAP/TEAD4-induced KIF4A contributes to the progression and worse prognosis of esophageal squamous cell carcinoma.
BACH1 is transcriptionally inhibited by TET1 in hepatocellular carcinoma in a microRNA-34a-dependent manner to regulate autophagy and inflammation.
HDAC6 suppresses microRNA-199a transcription and augments HPV-positive cervical cancer progression through Wnt5a upregulation.
G3BP1 interacts with YWHAZ to regulate chemoresistance and predict adjuvant chemotherapy benefit in gastric cancer.
Histone deacetylase 10 exerts anti-tumor effects on cervical cancer via a novel microRNA-223/TXNIP/Wnt/β-catenin pathway.
iASPP protects the heart from ischemia injury by inhibiting p53 expression and cardiomyocyte apoptosis.
Impact of knockdown LincRNA-Cox2 on apoptosis of macrophage infected with Bacillus Calmette-Guérin.
Design, Synthesis, and Activity Evaluation of Novel Acyclic Nucleosides as Potential Anticancer Agents In Vitro and In Vivo.
Vascular endothelial cell-secreted exosomes facilitate osteoarthritis pathogenesis by promoting chondrocyte apoptosis.
BAIAP2L2 promotes the proliferation, migration and invasion of osteosarcoma associated with the Wnt/β-catenin pathway.
Dapagliflozin Improves Cardiac Function, Remodeling, Myocardial Apoptosis, and Inflammatory Cytokines in Mice with Myocardial Infarction.
Structural analysis of Panax ginseng glycoproteins and its anti-oligoasthenozoospermia effect in vivo.
Methylation of miR-19b-3p promoter exacerbates inflammatory responses in sepsis-induced ALI via targeting KLF7.
Ring finger protein 19A is overexpressed in non-small cell lung cancer and mediates p53 ubiquitin-degradation to promote cancer growth.
circBTBD7 Promotes Immature Porcine Sertoli Cell Growth through Modulating miR-24-3p/MAPK7 Axis to Inactivate p38 MAPK Signaling Pathway.
Protection of pancreatic β-cell by phosphocreatine through mitochondrial improvement via the regulation of dual AKT/IRS-1/GSK-3β and STAT3/Cyp-D signaling pathways.
Thyroid stimulating hormone aggravates diabetic retinopathy through the mitochondrial apoptotic pathway.
Regulation of Bax-dependent apoptosis by mitochondrial deubiquitinase USP30.
Limonin induces apoptosis of HL-60 cells by inhibiting NQO1 activity.
Histone deacetylase 10 exerts antitumor effects on cervical cancer via a novel microRNA-223/TXNIP/Wnt/β-catenin pathway.
miR-101-3p sensitizes lung adenocarcinoma cells to irradiation via targeting BIRC5.
Dracomolphin A-E, new lignans from Dracocephalum moldavica.
Glaucocalyxin A induces cell cycle arrest and apoptosis via inhibiting NF-κB/p65 signaling pathway in melanoma cells.
Anticancer Activity of Tetrandrine by Inducing Apoptosis in Human Breast Cancer Cell Line MDA-MB-231 In Vivo.
AdipoRon Protects against Tubular Injury in Diabetic Nephropathy by Inhibiting Endoplasmic Reticulum Stress.
Galangin Inhibits Cholangiocarcinoma Cell Growth and Metastasis through Downregulation of MicroRNA-21 Expression.
Sepsis causes heart injury through endoplasmic reticulum stress-mediated apoptosis signaling pathway.
PRDX2 plays an oncogenic role in esophageal squamous cell carcinoma via Wnt/β-catenin and AKT pathways.
HIF-1α ameliorates tubular injury in diabetic nephropathy via HO-1-mediated control of mitochondrial dynamics.
Thymosin alpha-1 blocks the accumulation of myeloid suppressor cells in NSCLC by inhibiting VEGF production.
Morusin induces apoptosis and autophagy via JNK, ERK and PI3K/Akt signaling in human lung carcinoma cells.
Synthesis and biological evaluations of N'-substituted methylene-4-(quinoline-4-amino) benzoylhydrazides as potential anti-hepatoma agents.
Cyclovirobuxine D Exerts Anticancer Effects by Suppressing the EGFR-FAK-AKT/ERK1/2-Slug Signaling Pathway in Human Hepatocellular Carcinoma.
Insights into mechanisms of pranoprofen-induced apoptosis and necroptosis in human corneal stromal cells.
Long noncoding RNA linc00467 plays an oncogenic role in hepatocellular carcinoma by regulating the miR-18a-5p/NEDD9 axis.
Cafestol preconditioning attenuates apoptosis and autophagy during hepatic ischemia-reperfusion injury by inhibiting ERK/PPARγ pathway.
Thermosensitive heparin-poloxamer hydrogel encapsulated bFGF and NGF to treat spinal cord injury.
Protective Effects of Ischemic Postconditioning on Livers in Rats with Limb Ischemia-Reperfusion via Glycogen Synthase Kinase 3 beta (GSK-3β)/Fyn/Nuclear Receptor-Erythroid-2-Related Factor (Nrf2) Pathway.
Epigenetic upregulation of HOXC10 in non-small lung cancer cells.
Intracellular expression of arginine deiminase activates the mitochondrial apoptosis pathway by inhibiting cytosolic ferritin and inducing chromatin autophagy.
Anti-CD19 mAb-conjugated human serum albumin nanoparticles effectively deliver doxorubicin to B-lymphoblastic leukemia cells.
Hydroxypropyl‑β‑cyclodextrin attenuates the epithelial‑to‑mesenchymal transition via endoplasmic reticulum stress in MDA‑MB‑231 breast cancer cells.
Simvastatin re-sensitizes hepatocellular carcinoma cells to sorafenib by inhibiting HIF-1α/PPAR-γ/PKM2-mediated glycolysis.
Osthole induces cell cycle arrest and apoptosis in head and neck squamous cell carcinoma by suppressing the PI3K/AKT signaling pathway.
Ubiquitination of NOTCH2 by DTX3 suppresses the proliferation and migration of human esophageal carcinoma.
Human cathelicidin antimicrobial peptide suppresses proliferation, migration and invasion of oral carcinoma HSC-3 cells via a novel mechanism involving caspase-3 mediated apoptosis.
NFIB functions as an oncogene in estrogen receptor-positive breast cancer and is regulated by miR-205-5p.
Exosome-mediated Hic-5 regulates proliferation and apoptosis of osteosarcoma via Wnt/β-catenin signal pathway.
Physicochemical characterization of polysaccharide from the leaf of Dendrobium officinale and effect on LPS induced damage in GES-1 cell.
Human mesenchymal stromal cells ameliorate complement induced inflammatory cascade and improve renal functions in a rat model of ischemia-reperfusion induced acute kidney injury.
siPRDX2-elevated DNM3 inhibits the proliferation and metastasis of colon cancer cells via AKT signaling pathway.
NKAP functions as an oncogene in Ewing sarcoma cells partly through the AKT signaling pathway.
Anti-Inflammatory and Anti-Apoptotic Effects of Stybenpropol A on Human Umbilical Vein Endothelial Cells.
Regulating glycolysis, the TLR4 signal pathway and expression of RBM3 in mouse liver in response to acute cold exposure.
PKM2 is the target of proanthocyanidin B2 during the inhibition of hepatocellular carcinoma.
Inhibition of Connexin43 hemichannels with Gap19 protects cerebral ischemia/reperfusion injury via the JAK2/STAT3 pathway in mice.
Effects of Cold-inducible RNA-binding Protein (CIRP) on Liver Glycolysis during Acute Cold Exposure in C57BL/6 Mice.
Tamibarotene Improves Hippocampus Injury Induced by Focal Cerebral Ischemia-Reperfusion via Modulating PI3K/Akt Pathway in Rats.
MicroRNA-2053 overexpression inhibits the development and progression of hepatocellular carcinoma.
Magnesium isoglycyrrhizinate ameliorates fructose-induced podocyte apoptosis through downregulation of miR-193a to increase WT1.
The Antiapoptosis Effect of Geum japonicum Thunb. var. chinense Extracts on Cerebral Ischemia Reperfusion Injury via PI3K/Akt Pathway.
Alkaline ceramidase 3 promotes growth of hepatocellular carcinoma cells via regulating S1P/S1PR2/PI3K/AKT signaling.
UNBS5162 inhibits proliferation of human melanoma cells by inducing apoptosis via the PI3K/Akt pathway.
Effects of Acute Cold Stress on Liver O-GlcNAcylation and Glycometabolism in Mice.
LACTB, a novel epigenetic silenced tumor suppressor, inhibits colorectal cancer progression by attenuating MDM2-mediated p53 ubiquitination and degradation.
DNMTs inhibitor SGI-1027 induces apoptosis in Huh7 human hepatocellular carcinoma cells.
UNBS5162 induces growth inhibition and apoptosis via inhibiting PI3K/AKT/mTOR pathway in triple negative breast cancer MDA-MB-231 cells.
All-Trans Retinoic Acid Ameliorates the Early Experimental Cerebral Ischemia-Reperfusion Injury in Rats by Inhibiting the Loss of the Blood-Brain Barrier via the JNK/P38MAPK Signaling Pathway.
Salidroside mediates apoptosis and autophagy inhibition in concanavalin A-induced liver injury.
Hypothermic machine perfusion attenuates ischemia/reperfusion injury against rat livers donated after cardiac death by activating the Keap1/Nrf2‑ARE signaling pathway.
14-3-3ε is a nuclear matrix protein, and its altered expression and localization are associated with curcumin-induced apoptosis of MG-63 cells.
Sphingomyelin synthase 2 promotes H2O2-induced endothelial dysfunction by activating the Wnt/β-catenin signaling pathway.
Influencing mechanism of magnolol on expression of BDNF and Bax in rats with cerebral ischemic stroke.
Morroniside protects SK-N-SH human neuroblastoma cells against H2O2-induced damage.
Anti-tumor effect of evodiamine by inducing Akt-mediated apoptosis in hepatocellular carcinoma.
Resveratrol sequentially induces replication and oxidative stresses to drive p53-CXCR2 mediated cellular senescence in cancer cells.
The role of the ATM/Chk/P53 pathway in mediating DNA damage in hand-foot syndrome induced by PLD.
Hyperlipidemia-induced apoptosis of hippocampal neurons in apoE(-/-) mice may be associated with increased PCSK9 expression.
Hepatoprotective effect of quercetin via TRAF6/JNK pathway in acute hepatitis.
Effects of dimethyl carbonate-induced autophagic activation on follicular development in the mouse ovary.
Mesenchymal stem cell conditioned medium alleviates oxidative stress injury induced by hydrogen peroxide via regulating miR143 and its target protein in hepatocytes.
Ghrelin Protects against Dexamethasone-Induced INS-1 Cell Apoptosis via ERK and p38MAPK Signaling.
Hsp70 suppresses apoptosis of BRL cells by regulating the expression of Bcl-2, cytochrome C, and caspase 8/3.
Marine Bromophenol Derivative 3,4-Dibromo-5-(2-bromo-3,4-dihydroxy-6-isopropoxymethyl benzyl)benzene-1,2-diol Protects Hepatocytes from Lipid-Induced Cell Damage and Insulin Resistance via PTP1B Inhibition.
Zhang Y, Li Y, Wang Q, Zheng D, Feng X, Zhao W, Cai L, Zhang Q, Xu H, Fu H
International journal of molecular medicine 2022 Feb;49(2)
International journal of molecular medicine 2022 Feb;49(2)
CTRP1 Attenuates Cerebral Ischemia/Reperfusion Injury via the PERK Signaling Pathway.
Fei H, Xiang P, Luo W, Tan X, Gu C, Liu M, Chen M, Wang Q, Yang J
Frontiers in cell and developmental biology 2021;9:700854
Frontiers in cell and developmental biology 2021;9:700854
NLGN3 Upregulates Expression of ADAM10 to Promote the Cleavage of NLGN3 via Activating the LYN Pathway in Human Gliomas.
Dang NN, Li XB, Zhang M, Han C, Fan XY, Huang SH
Frontiers in cell and developmental biology 2021;9:662763
Frontiers in cell and developmental biology 2021;9:662763
Cold-Induced RNA-Binding Protein Promotes Glucose Metabolism and Reduces Apoptosis by Increasing AKT Phosphorylation in Mouse Skeletal Muscle Under Acute Cold Exposure.
Liu Y, Liu P, Hu Y, Cao Y, Lu J, Yang Y, Lv H, Lian S, Xu B, Li S
Frontiers in molecular biosciences 2021;8:685993
Frontiers in molecular biosciences 2021;8:685993
Cannabisin D from Sinomenium Acutum Inhibits Proliferation and Migration of Glioblastoma Cells through MAPKs Signaling.
Zhang D, Li C, Zhang L, Li B, Wang Y, Wang R, Chen Z, Xu L, Liu T
Nutrition and cancer 2021;73(11-12):2491-2501
Nutrition and cancer 2021;73(11-12):2491-2501
Expression of Ubiquitin-specific protease 7 in oral squamous cell carcinoma promotes tumor cell proliferation and invasion.
Yang X, Jin J, Yang J, Zhou L, Mi S, Qi G
Genetics and molecular biology 2021;44(4):e20210058
Genetics and molecular biology 2021;44(4):e20210058
Erteng-Sanjie Capsule Enhances Chemosensitivity of 5-Fluorouracil in Tumor-Bearing Nude Mice with Gastric Cancer by Inhibiting Notch1/Hes1 Signaling Pathway.
Zhou J, Hao S, Guo H, Yu H, Guo Z, Liu L
Evidence-based complementary and alternative medicine : eCAM 2021;2021:9980565
Evidence-based complementary and alternative medicine : eCAM 2021;2021:9980565
Study on Protection of Human Umbilical Vein Endothelial Cells from Amiodarone-Induced Damage by Intermedin through Activation of Wnt/β-Catenin Signaling Pathway.
Wang Y, Wang J, Yang J, Kang J, Xue F, Chang S, Ji H, Zang H, Zhou X, Wang G, Fan W, Yan X, Guo J, Ren X, Tian J
Oxidative medicine and cellular longevity 2021;2021:8889408
Oxidative medicine and cellular longevity 2021;2021:8889408
Tetrandrine Ameliorates Myocardial Ischemia Reperfusion Injury through miR-202-5p/TRPV2.
Zhao W, Wu Y, Ye F, Huang S, Chen H, Zhou R, Jiang W
BioMed research international 2021;2021:8870674
BioMed research international 2021;2021:8870674
Farrerol Enhances Nrf2-Mediated Defense Mechanisms against Hydrogen Peroxide-Induced Oxidative Damage in Human Retinal Pigment Epithelial Cells by Activating Akt and MAPK.
Ma N, Yang X, Qi C, Yu Q, Zhu C, Ren H
Oxidative medicine and cellular longevity 2021;2021:8847844
Oxidative medicine and cellular longevity 2021;2021:8847844
Wenxin Granules Regulate Endoplasmic Reticulum Stress Unfolded Protein Response and Improve Ventricular Remodeling on Rats with Myocardial Infarction.
Liu K, Lv M, Ji X, Lou L, Nie B, Zhao J, Wu A, Zhao M
Evidence-based complementary and alternative medicine : eCAM 2021;2021:7375549
Evidence-based complementary and alternative medicine : eCAM 2021;2021:7375549
Bioactive Peptide F2d Isolated from Rice Residue Exerts Antioxidant Effects via Nrf2 Signaling Pathway.
Liu J, Wu Q, Yang T, Yang F, Guo T, Zhou Y, Han S, Luo Y, Guo T, Luo F, Lin Q
Oxidative medicine and cellular longevity 2021;2021:2637577
Oxidative medicine and cellular longevity 2021;2021:2637577
Luteolin Improves Cyclophosphamide-Induced Cystitis through TXNIP/NLRP3 and NF-κB Pathways.
Zhang H, Zhao J, Lu Q, Sun B, Liu X, Yang C, Li S, Li L, Yi S, Yang Z, Xu J
Evidence-based complementary and alternative medicine : eCAM 2021;2021:1718709
Evidence-based complementary and alternative medicine : eCAM 2021;2021:1718709
Qingda granule exerts neuroprotective effects against ischemia/reperfusion-induced cerebral injury via lncRNA GAS5/miR-137 signaling pathway.
Zhang L, Cai Q, Lin S, Chen B, Jia B, Ye R, Weygant N, Chu J, Peng J
International journal of medical sciences 2021;18(7):1687-1698
International journal of medical sciences 2021;18(7):1687-1698
Hyperbaric Oxygen Therapy Attenuates Burn-Induced Denervated Muscle Atrophy.
Chen CA, Huang YC, Lo JJ, Wang SH, Huang SH, Wu SH
International journal of medical sciences 2021;18(16):3821-3830
International journal of medical sciences 2021;18(16):3821-3830
Therapeutic Efficacy of Carbon Ion Irradiation Enhanced by 11-MUA-Capped Gold Nanoparticles: An in vitro and in vivo Study.
Zhang P, Yu B, Jin X, Zhao T, Ye F, Liu X, Li P, Zheng X, Chen W, Li Q
International journal of nanomedicine 2021;16:4661-4674
International journal of nanomedicine 2021;16:4661-4674
Inhibition of mu-opioid receptor suppresses proliferation of hepatocellular carcinoma cells via CD147-p53-MAPK cascade signaling pathway.
Zhang JJ, Song CG, Dai JM, Zhang XQ, Lin P, Li L, Yang XM, Chen ZN
American journal of translational research 2021;13(5):3967-3986
American journal of translational research 2021;13(5):3967-3986
The COL11A1/Akt/CREB signaling axis enables mitochondrial-mediated apoptotic evasion to promote chemoresistance in pancreatic cancer cells through modulating BAX/BCL-2 function.
Wang H, Ren R, Yang Z, Cai J, Du S, Shen X
Journal of Cancer 2021;12(5):1406-1420
Journal of Cancer 2021;12(5):1406-1420
Elevated HNF1A expression promotes radiation-resistance via driving PI3K/AKT signaling pathway in esophageal squamous cell carcinoma cells.
Zou N, Zhang X, Li S, Li Y, Zhao Y, Yang X, Zhu S
Journal of Cancer 2021;12(16):5013-5024
Journal of Cancer 2021;12(16):5013-5024
MicroRNA-455-5p Contributes to Cholangiocarcinoma Growth and Mediates Galangin's Anti-Tumor Effects.
Deng X, Zuo M, Pei Z, Xie Y, Yang Z, Zhang Z, Jiang M, Kuang D
Journal of Cancer 2021;12(15):4710-4721
Journal of Cancer 2021;12(15):4710-4721
Kaempferol Ameliorates the Inhibitory Activity of Dexamethasone in the Osteogenesis of MC3T3-E1 Cells by JNK and p38-MAPK Pathways.
Xie B, Zeng Z, Liao S, Zhou C, Wu L, Xu D
Frontiers in pharmacology 2021;12:739326
Frontiers in pharmacology 2021;12:739326
miR-25 Regulates Gastric Cancer Cell Growth and Apoptosis by Targeting EGR2.
Yang L, Li L, Chang P, Wei M, Chen J, Zhu C, Jia J
Frontiers in genetics 2021;12:690196
Frontiers in genetics 2021;12:690196
Elevated Serum FGG Levels Prognosticate and Promote the Disease Progression in Prostate Cancer.
Peng HH, Wang JN, Xiao LF, Yan M, Chen SP, Wang L, Yang K
Frontiers in genetics 2021;12:651647
Frontiers in genetics 2021;12:651647
Proteomic analysis reveals ginsenoside Rb1 attenuates myocardial ischemia/reperfusion injury through inhibiting ROS production from mitochondrial complex I.
Jiang L, Yin X, Chen YH, Chen Y, Jiang W, Zheng H, Huang FQ, Liu B, Zhou W, Qi LW, Li J
Theranostics 2021;11(4):1703-1720
Theranostics 2021;11(4):1703-1720
Endoplasmic reticulum stress is involved in retinal injury induced by repeated transient spikes of intraocular pressure.
Yang X, Yu X, Zhao Z, He Y, Zhang J, Su X, Sun N, Fan Z
Journal of Zhejiang University. Science. B 2021 Sept 15;22(9):746-756
Journal of Zhejiang University. Science. B 2021 Sept 15;22(9):746-756
Effects of Ganfule capsule on microbial and metabolic profiles in anti-hepatocellular carcinoma.
Xu F, Li H, Pan Y, Zeng Y, Li J, Li S
Journal of applied microbiology 2021 Sep 26;
Journal of applied microbiology 2021 Sep 26;
Hydroxychloroquine alleviates the neurotoxicity induced by anti-ribosomal P antibodies.
Zhao X, Yang P
Journal of neuroimmunology 2021 Sep 15;358:577648
Journal of neuroimmunology 2021 Sep 15;358:577648
Oridonin prevents oxidative stress-induced endothelial injury via promoting Nrf-2 pathway in ischaemic stroke.
Li L, Cheng SQ, Guo W, Cai ZY, Sun YQ, Huang XX, Yang J, Ji J, Chen YY, Dong YF, Cheng H, Sun XL
Journal of cellular and molecular medicine 2021 Oct;25(20):9753-9766
Journal of cellular and molecular medicine 2021 Oct;25(20):9753-9766
Inhibition of autophagy with Chloroquine enhanced apoptosis induced by 5-aminolevulinic acid-photodynamic therapy in secondary hyperparathyroidism primary cells and organoids.
Zeng L, Zou Q, Huang P, Xiong L, Cheng Y, Chen Q, Li Y, He H, Yi W, Wei W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Oct;142:111994
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Oct;142:111994
EphA2 inhibits SRA01/04 cells apoptosis by suppressing autophagy via activating PI3K/Akt/mTOR pathway.
Han J, Wang L, Lv H, Liu J, Dong Y, Shi L, Ji Q
Archives of biochemistry and biophysics 2021 Oct 30;711:109024
Archives of biochemistry and biophysics 2021 Oct 30;711:109024
Aronia melanocarpa polysaccharide ameliorates inflammation and aging in mice by modulating the AMPK/SIRT1/NF-κB signaling pathway and gut microbiota.
Zhao Y, Liu X, Zheng Y, Liu W, Ding C
Scientific reports 2021 Oct 18;11(1):20558
Scientific reports 2021 Oct 18;11(1):20558
Mechanism of a new photosensitizer (TBZPy) in the treatment of high-risk human papillomavirus-related diseases.
Li Z, Xiao Z, Feng Y, Wang Q, Teng M
Photodiagnosis and photodynamic therapy 2021 Oct 17;:102591
Photodiagnosis and photodynamic therapy 2021 Oct 17;:102591
Bioactive substances in the stratum corneum of the epidermis found as indicators of skin damage due to sun exposure.
Fukunaga A, Fukushima S, Iwata H, Nakahara M, Sasaki R, Baba N, Matsunaka H, Murakami Y, Furue M, Nishigori C
Photodermatology, photoimmunology & photomedicine 2021 Oct 17;
Photodermatology, photoimmunology & photomedicine 2021 Oct 17;
LncDACH1 promotes mitochondrial oxidative stress of cardiomyocytes by interacting with sirtuin3 and aggravates diabetic cardiomyopathy.
Zhang Q, Li D, Dong X, Zhang X, Liu J, Peng L, Meng B, Hua Q, Pei X, Zhao L, Hu X, Zhang Y, Pan Z, Lu Y, Yang B
Science China. Life sciences 2021 Oct 14;
Science China. Life sciences 2021 Oct 14;
m6A-mediated upregulation of AC008 promotes osteoarthritis progression through the miR-328-3p‒AQP1/ANKH axis.
Yang J, Zhang M, Yang D, Ma Y, Tang Y, Xing M, Li L, Chen L, Jin Y, Ma C
Experimental & molecular medicine 2021 Nov;53(11):1723-1734
Experimental & molecular medicine 2021 Nov;53(11):1723-1734
Abnormally elevated ubiquilin‑1 expression in breast cancer regulates metastasis and stemness via AKT signaling.
Feng X, Cao A, Qin T, Zhang Q, Fan S, Wang B, Song B, Yu X, Li L
Oncology reports 2021 Nov;46(5)
Oncology reports 2021 Nov;46(5)
Virtual screening based identification of miltefosine and octenidine as inhibitors of heat shock protein 90.
Li L, Yang M, Li C, Liu Y
Naunyn-Schmiedeberg's archives of pharmacology 2021 Nov;394(11):2223-2232
Naunyn-Schmiedeberg's archives of pharmacology 2021 Nov;394(11):2223-2232
SC66 inhibits the proliferation and induces apoptosis of human bladder cancer cells by targeting the AKT/β-catenin pathway.
Chen W, Zhao S, Yu W, Rao T, Ruan Y, Zhu S, Xia Y, Song H, Cheng F
Journal of cellular and molecular medicine 2021 Nov;25(22):10684-10697
Journal of cellular and molecular medicine 2021 Nov;25(22):10684-10697
Metformin attenuates H(2)O(2)-induced osteoblast apoptosis by regulating SIRT3 via the PI3K/AKT pathway.
Yang K, Pei L, Zhou S, Tao L, Zhu Y
Experimental and therapeutic medicine 2021 Nov;22(5):1316
Experimental and therapeutic medicine 2021 Nov;22(5):1316
The inhibitory effect Polygonum Cillinerve polysaccharide on transmissible gastroenteritis virus of swine.
Pan X, Zhou Y, Duan X, Cui J, Liu J, Song X, Ma W, Zhang W, Liu Y, Fan Y
Research in veterinary science 2021 Nov;140:47-55
Research in veterinary science 2021 Nov;140:47-55
Alnustone inhibits the growth of hepatocellular carcinoma via ROS- mediated PI3K/Akt/mTOR/p70S6K axis.
Wang L, Cheng L, Ma L, Ahmad Farooqi A, Qiao G, Zhang Y, Ye H, Liu M, Huang J, Yang X, Lin X, Cao S
Phytotherapy research : PTR 2021 Nov 30;
Phytotherapy research : PTR 2021 Nov 30;
CCAAT/Enhancer-Binding Protein Homologous Protein (CHOP) Deficiency Attenuates Heatstroke-Induced Intestinal Injury.
Cao Y, Fan M, Pei Y, Su L, Xiao W, Chen F, Huang J, Liu X, Gu Z, Zhang Z, Yuan F, Jiang Y, Han X
Inflammation 2021 Nov 29;
Inflammation 2021 Nov 29;
Inhibition of Ras protein activator like 2 produces antitumor effects in gastric cancer via the suppression of YAP1 activation.
Hu Y, Zhang P, Shi Y, Dong X, Wu Y, Dong D, Li E, Fan Y
Environmental toxicology 2021 Nov 26;
Environmental toxicology 2021 Nov 26;
Morphine promotes the malignant biological behavior of non-small cell lung cancer cells through the MOR/Src/mTOR pathway.
Liu X, Yang J, Yang C, Huang X, Han M, Kang F, Li J
Cancer cell international 2021 Nov 25;21(1):622
Cancer cell international 2021 Nov 25;21(1):622
Prodrug polymeric micelles integrating cancer-associated fibroblasts deactivation and synergistic chemotherapy for gastric cancer.
Zheng S, Wang J, Ding N, Chen W, Chen H, Xue M, Chen F, Ni J, Wang Z, Lin Z, Jiang H, Liu X, Wang L
Journal of nanobiotechnology 2021 Nov 21;19(1):381
Journal of nanobiotechnology 2021 Nov 21;19(1):381
The Effects of Flavonoid Apigenin on Male Reproductive Health: Inhibition of Spermatogonial Proliferation through Downregulation of Prmt7/Akt3 Pathway.
Wang B, Zhang M, Guo J, Liu Z, Zhou R, Guo F, Li K, Mu Y
International journal of molecular sciences 2021 Nov 11;22(22)
International journal of molecular sciences 2021 Nov 11;22(22)
Sodium cantharidate induces Apoptosis in breast cancer cells by regulating energy metabolism via the protein phosphatase 5-p53 axis.
Pang JL, Huang FH, Zhang YH, Wu Y, Ge XM, Li S, Li X
Toxicology and applied pharmacology 2021 Nov 1;430:115726
Toxicology and applied pharmacology 2021 Nov 1;430:115726
Methylation gene KCNC1 is associated with overall survival in patients with seminoma.
Chen S, Xiao L, Peng H, Wang Z, Xie J
Oncology reports 2021 May;45(5)
Oncology reports 2021 May;45(5)
Toxicological and physiological effects of successive exposure to ochratoxin A at food regulatory limits.
Wei W, Liu C, Ke P, Chen X, Zhou T, Xu J, Zhou Y
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 May;151:112128
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 May;151:112128
Dual-Targeting Antiproliferation Hybrids Derived from 1-Deoxynojirimycin and Kaempferol Induce MCF-7 Cell Apoptosis through the Mitochondria-Mediated Pathway.
Zhang R, Zhang Y, Xin X, Huang G, Zhang N, Zeng Q, Tang L, Attaribo T, Lee KS, Jin BR, Gui Z
Journal of natural products 2021 May 28;84(5):1534-1543
Journal of natural products 2021 May 28;84(5):1534-1543
Upregulation of PPPDE1 contributes to anorectal malformations via the mitochondrial apoptosis pathway during hindgut development in rats.
Li SY, Wang CY, Zhao JJ, Long CY, Xiao YX, Tang XB, Yuan ZW, Bai YZ
Experimental cell research 2021 May 15;402(2):112574
Experimental cell research 2021 May 15;402(2):112574
Graphene oxide exacerbates dextran sodium sulfate-induced colitis via ROS/AMPK/p53 signaling to mediate apoptosis.
Liu S, Xu A, Gao Y, Xie Y, Liu Z, Sun M, Mao H, Wang X
Journal of nanobiotechnology 2021 Mar 25;19(1):85
Journal of nanobiotechnology 2021 Mar 25;19(1):85
Iguratimod-encapsulating PLGA-NPs induce human multiple myeloma cell death via reactive oxygen species and Caspase-dependent signalling.
Wang F, Younis M, Luo Y, Zhang L, Yuan L
International immunopharmacology 2021 Jun;95:107532
International immunopharmacology 2021 Jun;95:107532
Sparstolonin B exerts beneficial effects on prostate cancer by acting on the reactive oxygen species-mediated PI3K/AKT pathway.
Liu S, Hu J, Shi C, Sun L, Yan W, Song Y
Journal of cellular and molecular medicine 2021 Jun;25(12):5511-5524
Journal of cellular and molecular medicine 2021 Jun;25(12):5511-5524
O-GlcNAc / Akt pathway regulates glucose metabolism and reduces apoptosis in liver of piglets with acute cold stress.
Liu Y, Xu B, Hu Y, Liu P, Lian S, Lv H, Yang Y, Ji H, Yang H, Liu J, Yao R, Li S
Cryobiology 2021 Jun;100:125-132
Cryobiology 2021 Jun;100:125-132
Effects of β-Asarone on Ischemic Stroke in Middle Cerebral Artery Occlusion Rats by an Nrf2-Antioxidant Response Elements (ARE) Pathway-Dependent Mechanism.
Pan H, Xu Y, Cai Q, Wu M, Ding M
Medical science monitor : international medical journal of experimental and clinical research 2021 Jun 4;27:e931884
Medical science monitor : international medical journal of experimental and clinical research 2021 Jun 4;27:e931884
YAP/TEAD4-induced KIF4A contributes to the progression and worse prognosis of esophageal squamous cell carcinoma.
Li Y, Zhu X, Yang M, Wang Y, Li J, Fang J, Guo W, Ma S, Guan F
Molecular carcinogenesis 2021 Jul;60(7):440-454
Molecular carcinogenesis 2021 Jul;60(7):440-454
BACH1 is transcriptionally inhibited by TET1 in hepatocellular carcinoma in a microRNA-34a-dependent manner to regulate autophagy and inflammation.
Sun X, Zhu H, Cao R, Zhang J, Wang X
Pharmacological research 2021 Jul;169:105611
Pharmacological research 2021 Jul;169:105611
HDAC6 suppresses microRNA-199a transcription and augments HPV-positive cervical cancer progression through Wnt5a upregulation.
Shao Y, Zhu F, Zhu S, Bai L
The international journal of biochemistry & cell biology 2021 Jul;136:106000
The international journal of biochemistry & cell biology 2021 Jul;136:106000
G3BP1 interacts with YWHAZ to regulate chemoresistance and predict adjuvant chemotherapy benefit in gastric cancer.
Zhao J, Fu X, Chen H, Min L, Sun J, Yin J, Guo J, Li H, Tang Z, Ruan Y, Wang X, Sun Y, Huang L
British journal of cancer 2021 Jan;124(2):425-436
British journal of cancer 2021 Jan;124(2):425-436
Histone deacetylase 10 exerts anti-tumor effects on cervical cancer via a novel microRNA-223/TXNIP/Wnt/β-catenin pathway.
Zhu J, Han S
IUBMB life 2021 Jan 22;
IUBMB life 2021 Jan 22;
iASPP protects the heart from ischemia injury by inhibiting p53 expression and cardiomyocyte apoptosis.
Yagudin T, Zhao Y, Gao H, Zhang Y, Yang Y, Zhang X, Ma W, Daba TM, Ishmetov V, Kang K, Yang B, Pan Z
Acta biochimica et biophysica Sinica 2021 Jan 12;53(1):102-111
Acta biochimica et biophysica Sinica 2021 Jan 12;53(1):102-111
Impact of knockdown LincRNA-Cox2 on apoptosis of macrophage infected with Bacillus Calmette-Guérin.
Xu Y, Yu J, Ma C, Gong Z, Wu X, Deng G
Molecular immunology 2021 Feb;130:85-95
Molecular immunology 2021 Feb;130:85-95
Design, Synthesis, and Activity Evaluation of Novel Acyclic Nucleosides as Potential Anticancer Agents In Vitro and In Vivo.
Hao EJ, Li GX, Liang YR, Xie MS, Wang DC, Jiang XH, Cheng JY, Shi ZX, Wang Y, Guo HM
Journal of medicinal chemistry 2021 Feb 25;64(4):2077-2109
Journal of medicinal chemistry 2021 Feb 25;64(4):2077-2109
Vascular endothelial cell-secreted exosomes facilitate osteoarthritis pathogenesis by promoting chondrocyte apoptosis.
Yang RZ, Zheng HL, Xu WN, Zheng XF, Li B, Jiang LS, Jiang SD
Aging 2021 Feb 1;13(3):4647-4662
Aging 2021 Feb 1;13(3):4647-4662
BAIAP2L2 promotes the proliferation, migration and invasion of osteosarcoma associated with the Wnt/β-catenin pathway.
Guo H, Peng J, Hu J, Chang S, Liu H, Luo H, Chen X, Tang H, Chen Y
Journal of bone oncology 2021 Dec;31:100393
Journal of bone oncology 2021 Dec;31:100393
Dapagliflozin Improves Cardiac Function, Remodeling, Myocardial Apoptosis, and Inflammatory Cytokines in Mice with Myocardial Infarction.
Wang K, Li Z, Sun Y, Liu X, Ma W, Ding Y, Hong J, Qian L, Xu D
Journal of cardiovascular translational research 2021 Dec 2;
Journal of cardiovascular translational research 2021 Dec 2;
Structural analysis of Panax ginseng glycoproteins and its anti-oligoasthenozoospermia effect in vivo.
Shan M, Zhang X, Fang X, Tian J, Song L, Chen Y, Qiu Z, Zhu D, Luo H, Wang Z
International journal of biological macromolecules 2021 Dec 15;193(Pt A):778-788
International journal of biological macromolecules 2021 Dec 15;193(Pt A):778-788
Methylation of miR-19b-3p promoter exacerbates inflammatory responses in sepsis-induced ALI via targeting KLF7.
Jiang L, Wang M, Sun R, Lin Z, Liu R, Cai H, Tang Z, Zhang R
Cell biology international 2021 Aug;45(8):1666-1675
Cell biology international 2021 Aug;45(8):1666-1675
Ring finger protein 19A is overexpressed in non-small cell lung cancer and mediates p53 ubiquitin-degradation to promote cancer growth.
Cheng Y, Hu Y, Wang H, Zhao Z, Jiang X, Zhang Y, Zhang J, Tong Y, Qiu X
Journal of cellular and molecular medicine 2021 Aug;25(16):7796-7808
Journal of cellular and molecular medicine 2021 Aug;25(16):7796-7808
circBTBD7 Promotes Immature Porcine Sertoli Cell Growth through Modulating miR-24-3p/MAPK7 Axis to Inactivate p38 MAPK Signaling Pathway.
Bian Q, Chen B, Weng B, Chu D, Tang X, Yan S, Yin Y, Ran M
International journal of molecular sciences 2021 Aug 30;22(17)
International journal of molecular sciences 2021 Aug 30;22(17)
Protection of pancreatic β-cell by phosphocreatine through mitochondrial improvement via the regulation of dual AKT/IRS-1/GSK-3β and STAT3/Cyp-D signaling pathways.
Wang H, Ai J, Shopit A, Niu M, Ahmed N, Tesfaldet T, Tang Z, Li X, Jamalat Y, Chu P, Peng J, Ma X, Qaed E, Han G, Zhang W, Wang J, Tang Z
Cell biology and toxicology 2021 Aug 28;
Cell biology and toxicology 2021 Aug 28;
Thyroid stimulating hormone aggravates diabetic retinopathy through the mitochondrial apoptotic pathway.
Lin D, Qin R, Guo L
Journal of cellular physiology 2021 Aug 25;
Journal of cellular physiology 2021 Aug 25;
Regulation of Bax-dependent apoptosis by mitochondrial deubiquitinase USP30.
Yan D, Li X, Yang Q, Huang Q, Yao L, Zhang P, Sun W, Lin S, Dou QP, Liu J, Chen X
Cell death discovery 2021 Aug 11;7(1):211
Cell death discovery 2021 Aug 11;7(1):211
Limonin induces apoptosis of HL-60 cells by inhibiting NQO1 activity.
Chen Y, Liang J, Liang X, Chen J, Wang Y, Cao J, Sun C, Ye J, Chen Q
Food science & nutrition 2021 Apr;9(4):1860-1869
Food science & nutrition 2021 Apr;9(4):1860-1869
Histone deacetylase 10 exerts antitumor effects on cervical cancer via a novel microRNA-223/TXNIP/Wnt/β-catenin pathway.
Zhu J, Han S
IUBMB life 2021 Apr;73(4):690-704
IUBMB life 2021 Apr;73(4):690-704
miR-101-3p sensitizes lung adenocarcinoma cells to irradiation via targeting BIRC5.
Meng X, Sun Y, Liu S, Mu Y
Oncology letters 2021 Apr;21(4):282
Oncology letters 2021 Apr;21(4):282
Dracomolphin A-E, new lignans from Dracocephalum moldavica.
Zhang H, Wang S, Liu Q, Zheng H, Liu X, Wang X, Shen T, Ren D
Fitoterapia 2021 Apr;150:104841
Fitoterapia 2021 Apr;150:104841
Glaucocalyxin A induces cell cycle arrest and apoptosis via inhibiting NF-κB/p65 signaling pathway in melanoma cells.
Chen J, Zhang W, Pan C, Fan J, Zhong X, Tang S
Life sciences 2021 Apr 15;271:119185
Life sciences 2021 Apr 15;271:119185
Anticancer Activity of Tetrandrine by Inducing Apoptosis in Human Breast Cancer Cell Line MDA-MB-231 In Vivo.
Wang CH, Yang JM, Guo YB, Shen J, Pei XH
Evidence-based complementary and alternative medicine : eCAM 2020;2020:6823520
Evidence-based complementary and alternative medicine : eCAM 2020;2020:6823520
AdipoRon Protects against Tubular Injury in Diabetic Nephropathy by Inhibiting Endoplasmic Reticulum Stress.
Xiong S, Han Y, Gao P, Zhao H, Jiang N, Sun L
Oxidative medicine and cellular longevity 2020;2020:6104375
Oxidative medicine and cellular longevity 2020;2020:6104375
Galangin Inhibits Cholangiocarcinoma Cell Growth and Metastasis through Downregulation of MicroRNA-21 Expression.
Zou Y, Li R, Kuang D, Zuo M, Li W, Tong W, Jiang L, Zhou M, Chen Y, Gong W, Liu L, Tou F
BioMed research international 2020;2020:5846938
BioMed research international 2020;2020:5846938
Sepsis causes heart injury through endoplasmic reticulum stress-mediated apoptosis signaling pathway.
Li L, Peng X, Guo L, Zhao Y, Cheng Q
International journal of clinical and experimental pathology 2020;13(5):964-971
International journal of clinical and experimental pathology 2020;13(5):964-971
PRDX2 plays an oncogenic role in esophageal squamous cell carcinoma via Wnt/β-catenin and AKT pathways.
Feng AL, Han X, Meng X, Chen Z, Li Q, Shu W, Dai H, Zhu J, Yang Z
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2020 Oct;22(10):1838-1848
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2020 Oct;22(10):1838-1848
HIF-1α ameliorates tubular injury in diabetic nephropathy via HO-1-mediated control of mitochondrial dynamics.
Jiang N, Zhao H, Han Y, Li L, Xiong S, Zeng L, Xiao Y, Wei L, Xiong X, Gao P, Yang M, Liu Y, Sun L
Cell proliferation 2020 Nov;53(11):e12909
Cell proliferation 2020 Nov;53(11):e12909
Thymosin alpha-1 blocks the accumulation of myeloid suppressor cells in NSCLC by inhibiting VEGF production.
Yang Z, Guo J, Cui K, Du Y, Zhao H, Zhu L, Weng L, Tang W, Guo J, Zhang T, Shi X, Zong H, Jin S, Ma W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Nov;131:110740
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Nov;131:110740
Morusin induces apoptosis and autophagy via JNK, ERK and PI3K/Akt signaling in human lung carcinoma cells.
Wang J, Liu X, Zheng H, Liu Q, Zhang H, Wang X, Shen T, Wang S, Ren D
Chemico-biological interactions 2020 Nov 1;331:109279
Chemico-biological interactions 2020 Nov 1;331:109279
Synthesis and biological evaluations of N'-substituted methylene-4-(quinoline-4-amino) benzoylhydrazides as potential anti-hepatoma agents.
Li B, Zhu F, He F, Huang Q, Liu X, Wu T, Zhao T, Qiu Y, Wu Z, Xue Y, Fang M
Bioorganic chemistry 2020 Mar;96:103592
Bioorganic chemistry 2020 Mar;96:103592
Cyclovirobuxine D Exerts Anticancer Effects by Suppressing the EGFR-FAK-AKT/ERK1/2-Slug Signaling Pathway in Human Hepatocellular Carcinoma.
Zhang J, Chen Y, Lin J, Jia R, An T, Dong T, Zhang Y, Yang X
DNA and cell biology 2020 Mar;39(3):355-367
DNA and cell biology 2020 Mar;39(3):355-367
Insights into mechanisms of pranoprofen-induced apoptosis and necroptosis in human corneal stromal cells.
Lin Y, Yu M, Fan T
Toxicology letters 2020 Mar 1;320:9-18
Toxicology letters 2020 Mar 1;320:9-18
Long noncoding RNA linc00467 plays an oncogenic role in hepatocellular carcinoma by regulating the miR-18a-5p/NEDD9 axis.
Zheng Y, Nie P, Xu S
Journal of cellular biochemistry 2020 Jun;121(5-6):3135-3144
Journal of cellular biochemistry 2020 Jun;121(5-6):3135-3144
Cafestol preconditioning attenuates apoptosis and autophagy during hepatic ischemia-reperfusion injury by inhibiting ERK/PPARγ pathway.
Ji J, Wu L, Feng J, Mo W, Wu J, Yu Q, Li S, Zhang J, Dai W, Xu X, Mao Y, Xu S, Chen K, Li J, Guo C
International immunopharmacology 2020 Jul;84:106529
International immunopharmacology 2020 Jul;84:106529
Thermosensitive heparin-poloxamer hydrogel encapsulated bFGF and NGF to treat spinal cord injury.
Hu X, Li R, Wu Y, Li Y, Zhong X, Zhang G, Kang Y, Liu S, Xie L, Ye J, Xiao J
Journal of cellular and molecular medicine 2020 Jul;24(14):8166-8178
Journal of cellular and molecular medicine 2020 Jul;24(14):8166-8178
Protective Effects of Ischemic Postconditioning on Livers in Rats with Limb Ischemia-Reperfusion via Glycogen Synthase Kinase 3 beta (GSK-3β)/Fyn/Nuclear Receptor-Erythroid-2-Related Factor (Nrf2) Pathway.
Niu Q, Sun W, Chen Q, Long Y, Cao W, Wen S, Li A, Dong F, Shi H
Medical science monitor : international medical journal of experimental and clinical research 2020 Jul 20;26:e923049
Medical science monitor : international medical journal of experimental and clinical research 2020 Jul 20;26:e923049
Epigenetic upregulation of HOXC10 in non-small lung cancer cells.
Li M, Alsager JS, Wang Z, Cheng L, Shan B
Aging 2020 Jul 19;12(17):16921-16935
Aging 2020 Jul 19;12(17):16921-16935
Intracellular expression of arginine deiminase activates the mitochondrial apoptosis pathway by inhibiting cytosolic ferritin and inducing chromatin autophagy.
Feng Q, Bian X, Liu X, Wang Y, Zhou H, Ma X, Quan C, Yao Y, Zheng Z
BMC cancer 2020 Jul 16;20(1):665
BMC cancer 2020 Jul 16;20(1):665
Anti-CD19 mAb-conjugated human serum albumin nanoparticles effectively deliver doxorubicin to B-lymphoblastic leukemia cells.
Pan H, Li S, Li M, Tao Q, Jia J, Li W, Wang L, Guo Z, Ma K, Liu Y, Cui C
Die Pharmazie 2020 Jul 1;75(7):318-323
Die Pharmazie 2020 Jul 1;75(7):318-323
Hydroxypropyl‑β‑cyclodextrin attenuates the epithelial‑to‑mesenchymal transition via endoplasmic reticulum stress in MDA‑MB‑231 breast cancer cells.
Wu Y, Zhao Y, He X, He Z, Wang T, Wan L, Chen L, Yan N
Molecular medicine reports 2020 Jan;21(1):249-257
Molecular medicine reports 2020 Jan;21(1):249-257
Simvastatin re-sensitizes hepatocellular carcinoma cells to sorafenib by inhibiting HIF-1α/PPAR-γ/PKM2-mediated glycolysis.
Feng J, Dai W, Mao Y, Wu L, Li J, Chen K, Yu Q, Kong R, Li S, Zhang J, Ji J, Wu J, Mo W, Xu X, Guo C
Journal of experimental & clinical cancer research : CR 2020 Jan 30;39(1):24
Journal of experimental & clinical cancer research : CR 2020 Jan 30;39(1):24
Osthole induces cell cycle arrest and apoptosis in head and neck squamous cell carcinoma by suppressing the PI3K/AKT signaling pathway.
Yang J, Zhu XJ, Jin MZ, Cao ZW, Ren YY, Gu ZW
Chemico-biological interactions 2020 Jan 25;316:108934
Chemico-biological interactions 2020 Jan 25;316:108934
Ubiquitination of NOTCH2 by DTX3 suppresses the proliferation and migration of human esophageal carcinoma.
Ding XY, Hu HY, Huang KN, Wei RQ, Min J, Qi C, Tang H, Qin X
Cancer science 2020 Feb;111(2):489-501
Cancer science 2020 Feb;111(2):489-501
Human cathelicidin antimicrobial peptide suppresses proliferation, migration and invasion of oral carcinoma HSC-3 cells via a novel mechanism involving caspase-3 mediated apoptosis.
Chen X, Ji S, Si J, Zhang X, Wang X, Guo Y, Zou X
Molecular medicine reports 2020 Dec;22(6):5243-5250
Molecular medicine reports 2020 Dec;22(6):5243-5250
NFIB functions as an oncogene in estrogen receptor-positive breast cancer and is regulated by miR-205-5p.
Chen H, Yu C, Shen L, Wu Y, Wu D, Wang Z, Song G, Chen L, Hong Y
Pathology, research and practice 2020 Dec;216(12):153236
Pathology, research and practice 2020 Dec;216(12):153236
Exosome-mediated Hic-5 regulates proliferation and apoptosis of osteosarcoma via Wnt/β-catenin signal pathway.
Sha L, Ma D, Chen C
Aging 2020 Dec 13;12(23):23598-23608
Aging 2020 Dec 13;12(23):23598-23608
Physicochemical characterization of polysaccharide from the leaf of Dendrobium officinale and effect on LPS induced damage in GES-1 cell.
Yang K, Lu T, Zhan L, Zhou C, Zhang N, Lei S, Wang Y, Yang J, Yan M, Lv G, Chen S
International journal of biological macromolecules 2020 Apr 15;149:320-330
International journal of biological macromolecules 2020 Apr 15;149:320-330
Human mesenchymal stromal cells ameliorate complement induced inflammatory cascade and improve renal functions in a rat model of ischemia-reperfusion induced acute kidney injury.
Zilberman-Itskovich S, Abu-Hamad R, Zarura R, Sova M, Hachmo Y, Stark M, Neuman S, Slavin S, Efrati S
PloS one 2019;14(9):e0222354
PloS one 2019;14(9):e0222354
siPRDX2-elevated DNM3 inhibits the proliferation and metastasis of colon cancer cells via AKT signaling pathway.
Ma Y, Guan L, Han Y, Zhou Y, Li X, Liu Y, Zhang X, Zhang W, Li X, Wang S, Lu W
Cancer management and research 2019;11:5799-5811
Cancer management and research 2019;11:5799-5811
NKAP functions as an oncogene in Ewing sarcoma cells partly through the AKT signaling pathway.
Li F, Wu JT, Wang PF, Qu LZ
Experimental and therapeutic medicine 2019 Oct;18(4):3037-3045
Experimental and therapeutic medicine 2019 Oct;18(4):3037-3045
Anti-Inflammatory and Anti-Apoptotic Effects of Stybenpropol A on Human Umbilical Vein Endothelial Cells.
Zhang L, Wang F, Zhang Q, Liang Q, Wang S, Xian M, Wang F
International journal of molecular sciences 2019 Oct 29;20(21)
International journal of molecular sciences 2019 Oct 29;20(21)
Regulating glycolysis, the TLR4 signal pathway and expression of RBM3 in mouse liver in response to acute cold exposure.
Shi H, Yao R, Lian S, Liu P, Liu Y, Yang YY, Yang H, Li S
Stress (Amsterdam, Netherlands) 2019 May;22(3):366-376
Stress (Amsterdam, Netherlands) 2019 May;22(3):366-376
PKM2 is the target of proanthocyanidin B2 during the inhibition of hepatocellular carcinoma.
Feng J, Wu L, Ji J, Chen K, Yu Q, Zhang J, Chen J, Mao Y, Wang F, Dai W, Xu L, Wu J, Guo C
Journal of experimental & clinical cancer research : CR 2019 May 17;38(1):204
Journal of experimental & clinical cancer research : CR 2019 May 17;38(1):204
Inhibition of Connexin43 hemichannels with Gap19 protects cerebral ischemia/reperfusion injury via the JAK2/STAT3 pathway in mice.
Chen B, Yang L, Chen J, Chen Y, Zhang L, Wang L, Li X, Li Y, Yu H
Brain research bulletin 2019 Mar;146:124-135
Brain research bulletin 2019 Mar;146:124-135
Effects of Cold-inducible RNA-binding Protein (CIRP) on Liver Glycolysis during Acute Cold Exposure in C57BL/6 Mice.
Liu P, Yao R, Shi H, Liu Y, Lian S, Yang Y, Yang H, Li S
International journal of molecular sciences 2019 Mar 23;20(6)
International journal of molecular sciences 2019 Mar 23;20(6)
Tamibarotene Improves Hippocampus Injury Induced by Focal Cerebral Ischemia-Reperfusion via Modulating PI3K/Akt Pathway in Rats.
Tian X, An R, Luo Y, Li M, Xu L, Dong Z
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2019 Jul;28(7):1832-1840
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2019 Jul;28(7):1832-1840
MicroRNA-2053 overexpression inhibits the development and progression of hepatocellular carcinoma.
Song T, Ma K, Zhao C, Yang J, Liu J
Oncology letters 2019 Aug;18(2):2043-2049
Oncology letters 2019 Aug;18(2):2043-2049
Magnesium isoglycyrrhizinate ameliorates fructose-induced podocyte apoptosis through downregulation of miR-193a to increase WT1.
Li TS, Chen L, Wang SC, Yang YZ, Xu HJ, Gu HM, Zhao XJ, Dong P, Pan Y, Shang ZQ, Zhang XQ, Kong LD
Biochemical pharmacology 2019 Aug;166:139-152
Biochemical pharmacology 2019 Aug;166:139-152
The Antiapoptosis Effect of Geum japonicum Thunb. var. chinense Extracts on Cerebral Ischemia Reperfusion Injury via PI3K/Akt Pathway.
Ou B, Tao W, Yang S, Feng J, Wang J, Yang T, Wu H, Huang Y, Tan L, Huang W, Feng Z, Mei Z
Evidence-based complementary and alternative medicine : eCAM 2018;2018:7290170
Evidence-based complementary and alternative medicine : eCAM 2018;2018:7290170
Alkaline ceramidase 3 promotes growth of hepatocellular carcinoma cells via regulating S1P/S1PR2/PI3K/AKT signaling.
Yin Y, Xu M, Gao J, Li M
Pathology, research and practice 2018 Sep;214(9):1381-1387
Pathology, research and practice 2018 Sep;214(9):1381-1387
UNBS5162 inhibits proliferation of human melanoma cells by inducing apoptosis via the PI3K/Akt pathway.
Shi X, Yang L, Xie J, Zhao Y, Cong J, Li Z, Li H, Cheng X, Fan J
Molecular medicine reports 2018 Sep;18(3):3382-3388
Molecular medicine reports 2018 Sep;18(3):3382-3388
Effects of Acute Cold Stress on Liver O-GlcNAcylation and Glycometabolism in Mice.
Yao R, Yang Y, Lian S, Shi H, Liu P, Liu Y, Yang H, Li S
International journal of molecular sciences 2018 Sep 18;19(9)
International journal of molecular sciences 2018 Sep 18;19(9)
LACTB, a novel epigenetic silenced tumor suppressor, inhibits colorectal cancer progression by attenuating MDM2-mediated p53 ubiquitination and degradation.
Zeng K, Chen X, Hu X, Liu X, Xu T, Sun H, Pan Y, He B, Wang S
Oncogene 2018 Oct;37(41):5534-5551
Oncogene 2018 Oct;37(41):5534-5551
DNMTs inhibitor SGI-1027 induces apoptosis in Huh7 human hepatocellular carcinoma cells.
Sun N, Zhang J, Zhang C, Zhao B, Jiao A
Oncology letters 2018 Nov;16(5):5799-5806
Oncology letters 2018 Nov;16(5):5799-5806
UNBS5162 induces growth inhibition and apoptosis via inhibiting PI3K/AKT/mTOR pathway in triple negative breast cancer MDA-MB-231 cells.
Yue X, Li M, Chen D, Xu Z, Sun S
Experimental and therapeutic medicine 2018 Nov;16(5):3921-3928
Experimental and therapeutic medicine 2018 Nov;16(5):3921-3928
All-Trans Retinoic Acid Ameliorates the Early Experimental Cerebral Ischemia-Reperfusion Injury in Rats by Inhibiting the Loss of the Blood-Brain Barrier via the JNK/P38MAPK Signaling Pathway.
Li M, Tian X, An R, Yang M, Zhang Q, Xiang F, Liu H, Wang Y, Xu L, Dong Z
Neurochemical research 2018 Jun;43(6):1283-1296
Neurochemical research 2018 Jun;43(6):1283-1296
Salidroside mediates apoptosis and autophagy inhibition in concanavalin A-induced liver injury.
Feng J, Niu P, Chen K, Wu L, Liu T, Xu S, Li J, Li S, Wang W, Lu X, Yu Q, Liu N, Xu L, Wang F, Dai W, Xia Y, Fan X, Guo C
Experimental and therapeutic medicine 2018 Jun;15(6):4599-4614
Experimental and therapeutic medicine 2018 Jun;15(6):4599-4614
Hypothermic machine perfusion attenuates ischemia/reperfusion injury against rat livers donated after cardiac death by activating the Keap1/Nrf2‑ARE signaling pathway.
Xue S, He W, Zeng X, Tang Z, Feng S, Zhong Z, Xiong Y, Wang Y, Ye Q
Molecular medicine reports 2018 Jul;18(1):815-826
Molecular medicine reports 2018 Jul;18(1):815-826
14-3-3ε is a nuclear matrix protein, and its altered expression and localization are associated with curcumin-induced apoptosis of MG-63 cells.
Lu K, Rui G, Liu F, Yang L, Deng X, Shi S, Li Q
Oncology letters 2018 Jan;15(1):338-346
Oncology letters 2018 Jan;15(1):338-346
Sphingomyelin synthase 2 promotes H2O2-induced endothelial dysfunction by activating the Wnt/β-catenin signaling pathway.
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human testis tissue were subjected to SDS PAGE followed by western blot with 60267-1-Ig(BAX antibody) at dilution of 1:1000
- Sample type
- tissue
