STAT5B

gene product
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. [provided by RefSeq, Jul 2008]
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268 antibodies from 22 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Abnova Corporation
15 antibodies
Novus Biologicals
14 antibodies
R&D Systems
2 antibodies
Santa Cruz Biotechnology
1 antibody
Acris Antibodies GmbH
12 antibodies
antibodies-online
110 antibodies
LifeSpan BioSciences, Inc.
29 antibodies
Proteintech Group
2 antibodies
Aviva Systems Biology
8 antibodies
Thermo Fisher Scientific Pierce
4 antibodies
GeneTex
6 antibodies
Boster Immunoleader Biotechnology
1 antibody
Bethyl Laboratories, Inc.
1 antibody
RabMAbs
2 antibodies
Creative Biomart
32 antibodies
BioLegend
4 antibodies
United States Biological
10 antibodies
Abiocode, Inc.
1 antibody
EMD Millipore
6 antibodies
Sigma-Aldrich
5 antibodies
GenWay
2 antibodies
Active Motif
1 antibody