APR00020G

antibody from Leading Biology

Targeting: CDC42 CDC42Hs, G25K

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

APR00020G

Provider

Leading Biology

Product name

cdc42/Rac Antibody

Antibody type

Polyclonal

Description

cdc42/Rac belongs to the superfamily of small GTPases that are structurally linked to the proto-oncogene product p21ras and are important for the control of cell growth and differentiation as well as for intracellular organization. Cdc42/Rac is an important upstream regulator of the protein kinase cascade that controls the SAPK/JNK and p38 activity. Recent data also s μggest that constitutive active forms of cdc42 can induce apoptosis thro μgh a mechanism requiring signaling thro μgh SAPK/JNK.

Reactivity

Human, Mouse, Rat, Bovine

Host

Rabbit

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.