4156

antibody from Cell Signaling Technology, Inc

Targeting: RAPGEF4 cAMP-GEFII, CGEF2

Western blot (Data presented on provider website)

Antibody Data

Product number

4156

Provider

Cell Signaling Technology, Inc

Proper citation

Cell Signaling Technology Cat#4156, RRID:AB_1904112

Product name

EPAC2 (5B1) Mouse mAb

Antibody type

Monoclonal

Reactivity

Human, Mouse, Rat

Host

Mouse

Storage

-20°C

References

Submitted references

Enhanced leptin sensitivity, reduced adiposity, and improved glucose homeostasis in mice lacking exchange protein directly activated by cyclic AMP isoform 1.

Yan J, Mei FC, Cheng H, Lao DH, Hu Y, Wei J, Patrikeev I, Hao D, Stutz SJ, Dineley KT, Motamedi M, Hommel JD, Cunningham KA, Chen J, Cheng X
Molecular and cellular biology 2013 Mar;33(5):918-26

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Stimulation of proglucagon gene expression by human GPR119 in enteroendocrine L-cell line GLUTag.

Chepurny OG, Bertinetti D, Diskar M, Leech CA, Afshari P, Tsalkova T, Cheng X, Schwede F, Genieser HG, Herberg FW, Holz GG
Molecular endocrinology (Baltimore, Md.) 2013 Aug;27(8):1267-82

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Epac2-dependent mobilization of intracellular Ca²+ by glucagon-like peptide-1 receptor agonist exendin-4 is disrupted in β-cells of phospholipase C-ε knockout mice.

Dzhura I, Chepurny OG, Kelley GG, Leech CA, Roe MW, Dzhura E, Afshari P, Malik S, Rindler MJ, Xu X, Lu Y, Smrcka AV, Holz GG
The Journal of physiology 2010 Dec 15;588(Pt 24):4871-89