APR03884G

antibody from Leading Biology

Targeting: NFATC1 NF-ATC, NFAT2, NFATc

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

APR03884G

Provider

Leading Biology

Product name

NFATC1 Antibody (C-term)

Antibody type

Polyclonal

Description

The product of this gene is a component of the nuclearfactor of activated T cells DNA-binding transcription complex. Thiscomplex consists of at least two components: a preexistingcytosolic component that translocates to the nucleus upon T cellreceptor (TCR) stimulation, and an inducible nuclear component.Proteins belonging to this family of transcription factors play acentral role in inducible gene transcription during immuneresponse. The product of this gene is an inducible nuclearcomponent. It functions as a major molecular target for theimmunosuppressive drugs such as cyclosporin A. Five transcriptvariants encoding distinct isoforms have been identified for thisgene. Different isoforms of this protein may regulate inducibleexpression of different cytokine genes.

Reactivity

Human

Host

Rabbit

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.