Tissue expression
Cell line expression
Protein structure
KAT2B
Lysine acetyltransferase 2BGCN5, GCN5L, P/CAF, PCAF
CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation. [provided by RefSeq, Jul 2008]
Top validated antibodies |
|||||
Proteintech Group | ![]() |
4 references | Polyclonal |
|
|
LSBio | ![]() |
Polyclonal |
|
||
Invitrogen Antibodies | ![]() |
Monoclonal |
|
||
antibodies-online | ![]() |
Monoclonal |
|
||
Santa Cruz Biotechnology | ![]() |
4 references | Monoclonal |
|