Explore
Validate
Learn
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- MAB1080 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#MAB1080, RRID:AB_1578794
- Product name
- PIN1 monoclonal antibody, clone 3G8
- Antibody type
- Monoclonal
- Description
- Mouse monoclonal antibody raised against full length recombinant PIN1.
- Isotype
- IgG
- Antibody clone number
- 3G8
- Storage
- Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic insults.
Pin1: a therapeutic target in Alzheimer neurodegeneration.
Role of Pin1 in the regulation of p53 stability and p21 transactivation, and cell cycle checkpoints in response to DNA damage.
Zacchi P, Gostissa M, Uchida T, Salvagno C, Avolio F, Volinia S, Ronai Z, Blandino G, Schneider C, Del Sal G
Nature 2002 Oct 24;419(6909):853-7
Nature 2002 Oct 24;419(6909):853-7
Pin1: a therapeutic target in Alzheimer neurodegeneration.
Hamdane M, Smet C, Sambo AV, Leroy A, Wieruszeski JM, Delobel P, Maurage CA, Ghestem A, Wintjens R, Bégard S, Sergeant N, Delacourte A, Horvath D, Landrieu I, Lippens G, Buée L
Journal of molecular neuroscience : MN 2002 Dec;19(3):275-87
Journal of molecular neuroscience : MN 2002 Dec;19(3):275-87
Role of Pin1 in the regulation of p53 stability and p21 transactivation, and cell cycle checkpoints in response to DNA damage.
Wulf GM, Liou YC, Ryo A, Lee SW, Lu KP
The Journal of biological chemistry 2002 Dec 13;277(50):47976-9
The Journal of biological chemistry 2002 Dec 13;277(50):47976-9
No comments: Submit comment
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of 293T , HeLa and Jurkat cell lysates (each 50 ug) were resolved by SDS - PAGE , transferred to PVDF membrane and probed with PIN1 monoclonal antibody , clone 3G8 (1 : 500) (Cat # MAB1080). Proteins were visualized using a goat anti - mouse secondary antibody conjugated to HRP and an ECL detection system.
