CABT-L1548

antibody from Creative Diagnostics

Targeting: PRKCZ PKC2

Western blot (Recommended by provider)

Antibody Data

Product number

CABT-L1548

Provider

Creative Diagnostics

Product name

Rabbit Anti-Human PKC zeta monoclonal antibody, clone T.339.3

Antibody type

Monoclonal

Description

Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC. Alternative splicing results in multiple transcript variants encoding different isoforms.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

T.339.3

Storage

-20°C