Antibody data
- Antibody Data
- Antigen structure
- References [20]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 11947-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11947-1-AP, RRID:AB_2269388
- Product name
- RAB5A antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated RAB5A antibody (Cat. #11947-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Porcine Circovirus Type 3 Enters Into PK15 Cells Through Clathrin- and Dynamin-2-Mediated Endocytosis in a Rab5/Rab7 and pH-Dependent Fashion.
Capping protein regulates endosomal trafficking by controlling F-actin density around endocytic vesicles and recruiting RAB5 effectors.
Live imaging of intra-lysosome pH in cell lines and primary neuronal culture using a novel genetically encoded biosensor.
RAB7 activity is required for the regulation of mitophagy in oocyte meiosis and oocyte quality control during ovarian aging.
Structure-based discovery of neoandrographolide as a novel inhibitor of Rab5 to suppress cancer growth.
Interferon-Induced Transmembrane Protein 3 Is a Virus-Associated Protein Which Suppresses Porcine Reproductive and Respiratory Syndrome Virus Replication by Blocking Viral Membrane Fusion.
Atorvastatin Targets the Islet Mevalonate Pathway to Dysregulate mTOR Signaling and Reduce β-Cell Functional Mass.
The N-glycosylation of Equine Tetherin Affects Antiviral Activity by Regulating Its Subcellular Localization.
Tsg101 positively regulates physiologic-like cardiac hypertrophy through FIP3-mediated endosomal recycling of IGF-1R.
A crucial role for Arf6 in the response of commissural axons to Slit.
Rab5a suppresses autophagy to promote drug resistance in cancer cells.
Reduced graphene oxide triggered epithelial-mesenchymal transition in A549 cells.
Role of RAB5A in FSHR-mediated signal transduction in human granulosa cells.
Autophagy defects and related genetic variations in renal cell carcinoma with eosinophilic cytoplasmic inclusions.
Exosomes Exploit the Virus Entry Machinery and Pathway To Transmit Alpha Interferon-Induced Antiviral Activity.
Rab5a is overexpressed in oral cancer and promotes invasion through ERK/MMP signaling.
Expression of Rab5a correlates with tumor progression in pancreatic carcinoma.
Identification of TMEM230 mutations in familial Parkinson's disease.
MicroRNA-130a inhibits cell proliferation, invasion and migration in human breast cancer by targeting the RAB5A.
Semaphorin 3A activates the guanosine triphosphatase Rab5 to promote growth cone collapse and organize callosal axon projections.
Shi R, Hou L, Wei L, Quan R, Zhou B, Jiang H, Wang J, Zhu S, Song J, Wang D, Liu J
Frontiers in microbiology 2021;12:636307
Frontiers in microbiology 2021;12:636307
Capping protein regulates endosomal trafficking by controlling F-actin density around endocytic vesicles and recruiting RAB5 effectors.
Wang D, Ye Z, Wei W, Yu J, Huang L, Zhang H, Yue J
eLife 2021 Nov 19;10
eLife 2021 Nov 19;10
Live imaging of intra-lysosome pH in cell lines and primary neuronal culture using a novel genetically encoded biosensor.
Ponsford AH, Ryan TA, Raimondi A, Cocucci E, Wycislo SA, Fröhlich F, Swan LE, Stagi M
Autophagy 2021 Jun;17(6):1500-1518
Autophagy 2021 Jun;17(6):1500-1518
RAB7 activity is required for the regulation of mitophagy in oocyte meiosis and oocyte quality control during ovarian aging.
Jin X, Wang K, Wang L, Liu W, Zhang C, Qiu Y, Liu W, Zhang H, Zhang D, Yang Z, Wu T, Li J
Autophagy 2021 Jul 7;:1-18
Autophagy 2021 Jul 7;:1-18
Structure-based discovery of neoandrographolide as a novel inhibitor of Rab5 to suppress cancer growth.
Zhang J, Sun Y, Zhong LY, Yu NN, Ouyang L, Fang RD, Wang Y, He QY
Computational and structural biotechnology journal 2020;18:3936-3946
Computational and structural biotechnology journal 2020;18:3936-3946
Interferon-Induced Transmembrane Protein 3 Is a Virus-Associated Protein Which Suppresses Porcine Reproductive and Respiratory Syndrome Virus Replication by Blocking Viral Membrane Fusion.
Zhang A, Duan H, Zhao H, Liao H, Du Y, Li L, Jiang D, Wan B, Wu Y, Ji P, Zhou EM, Zhang G
Journal of virology 2020 Nov 23;94(24)
Journal of virology 2020 Nov 23;94(24)
Atorvastatin Targets the Islet Mevalonate Pathway to Dysregulate mTOR Signaling and Reduce β-Cell Functional Mass.
Shen L, Gu Y, Qiu Y, Cheng T, Nie A, Cui C, Fu C, Li T, Li X, Fu L, Wang Y, Ni Q, Wang Q, Wang W, Feng B
Diabetes 2020 Jan;69(1):48-59
Diabetes 2020 Jan;69(1):48-59
The N-glycosylation of Equine Tetherin Affects Antiviral Activity by Regulating Its Subcellular Localization.
Bai B, Wang XF, Zhang M, Na L, Zhang X, Zhang H, Yang Z, Wang X
Viruses 2020 Feb 16;12(2)
Viruses 2020 Feb 16;12(2)
Tsg101 positively regulates physiologic-like cardiac hypertrophy through FIP3-mediated endosomal recycling of IGF-1R.
Essandoh K, Deng S, Wang X, Jiang M, Mu X, Peng J, Li Y, Peng T, Wagner KU, Rubinstein J, Fan GC
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jun;33(6):7451-7466
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jun;33(6):7451-7466
A crucial role for Arf6 in the response of commissural axons to Slit.
Kinoshita-Kawada M, Hasegawa H, Hongu T, Yanagi S, Kanaho Y, Masai I, Mishima T, Chen X, Tsuboi Y, Rao Y, Yuasa-Kawada J, Wu JY
Development (Cambridge, England) 2019 Feb 4;146(3)
Development (Cambridge, England) 2019 Feb 4;146(3)
Rab5a suppresses autophagy to promote drug resistance in cancer cells.
Xu W, Shi Q, Qian X, Zhou B, Xu J, Zhu L, Feng L, Jin H, Wang X
American journal of translational research 2018;10(4):1229-1236
American journal of translational research 2018;10(4):1229-1236
Reduced graphene oxide triggered epithelial-mesenchymal transition in A549 cells.
Liao Y, Wang W, Huang X, Sun Y, Tian S, Cai P
Scientific reports 2018 Oct 12;8(1):15188
Scientific reports 2018 Oct 12;8(1):15188
Role of RAB5A in FSHR-mediated signal transduction in human granulosa cells.
Zhu K, Li S, Liu J, Hong Y, Chen ZJ, Du Y
Reproduction (Cambridge, England) 2018 Jun;155(6):505-514
Reproduction (Cambridge, England) 2018 Jun;155(6):505-514
Autophagy defects and related genetic variations in renal cell carcinoma with eosinophilic cytoplasmic inclusions.
Yu Z, Ma J, Li X, Liu Y, Li M, Wang L, Zhao M, He H, Zhang Y, Rao Q, Zhao D, Wang Y, Fan L, Li P, Liu Y, Liu F, Zhang F, Ye J, Yan Q, Guo S, Wang Z
Scientific reports 2018 Jul 2;8(1):9972
Scientific reports 2018 Jul 2;8(1):9972
Exosomes Exploit the Virus Entry Machinery and Pathway To Transmit Alpha Interferon-Induced Antiviral Activity.
Yao Z, Qiao Y, Li X, Chen J, Ding J, Bai L, Shen F, Shi B, Liu J, Peng L, Li J, Yuan Z
Journal of virology 2018 Dec 15;92(24)
Journal of virology 2018 Dec 15;92(24)
Rab5a is overexpressed in oral cancer and promotes invasion through ERK/MMP signaling.
Zhang D, Lu C, Ai H
Molecular medicine reports 2017 Oct;16(4):4569-4576
Molecular medicine reports 2017 Oct;16(4):4569-4576
Expression of Rab5a correlates with tumor progression in pancreatic carcinoma.
Li Y, Sun X, Ji D, Kong X, Liu D, Zhao Z, Yan J, Chen S
Virchows Archiv : an international journal of pathology 2017 May;470(5):527-536
Virchows Archiv : an international journal of pathology 2017 May;470(5):527-536
Identification of TMEM230 mutations in familial Parkinson's disease.
Deng HX, Shi Y, Yang Y, Ahmeti KB, Miller N, Huang C, Cheng L, Zhai H, Deng S, Nuytemans K, Corbett NJ, Kim MJ, Deng H, Tang B, Yang Z, Xu Y, Chan P, Huang B, Gao XP, Song Z, Liu Z, Fecto F, Siddique N, Foroud T, Jankovic J, Ghetti B, Nicholson DA, Krainc D, Melen O, Vance JM, Pericak-Vance MA, Ma YC, Rajput AH, Siddique T
Nature genetics 2016 Jul;48(7):733-9
Nature genetics 2016 Jul;48(7):733-9
MicroRNA-130a inhibits cell proliferation, invasion and migration in human breast cancer by targeting the RAB5A.
Pan Y, Wang R, Zhang F, Chen Y, Lv Q, Long G, Yang K
International journal of clinical and experimental pathology 2015;8(1):384-93
International journal of clinical and experimental pathology 2015;8(1):384-93
Semaphorin 3A activates the guanosine triphosphatase Rab5 to promote growth cone collapse and organize callosal axon projections.
Wu KY, He M, Hou QQ, Sheng AL, Yuan L, Liu F, Liu WW, Li G, Jiang XY, Luo ZG
Science signaling 2014 Aug 26;7(340):ra81
Science signaling 2014 Aug 26;7(340):ra81
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse brain tissue were subjected to SDS PAGE followed by western blot with 11947-1-AP(RAB5A antibody) at dilution of 1:500
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- rat brain tissue were subjected to SDS PAGE followed by western blot with 11947-1-AP( RAB5A Antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The RAB5A antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human RAB5A. This antibody recognizes human,mouse,rat antigen. The RAB5A antibody has been validated for the following applications: ELISA, IHC, WB analysis.