FNab09390

antibody from FineTest Biotech

Targeting: VDR NR1I1, PPP1R163

Provider product page for FNab09390

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Immunocytochemistry

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
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Product number: FNab09390 - Provider product page
Provider: FineTest Biotech
Product name: VDR antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding different proteins.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: vitamin D (1, 25- dihydroxyvitamin D3) receptor
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months (Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months (Avoid repeated freeze / thaw cycles.)

VDR protein structure - FNab09390 shown in red.