NB300-221
antibody from Novus Biologicals
Targeting: GAPDH
GAPD
Antibody data
- Antibody Data
- Antigen structure
- References [303]
- Comments [0]
- Validations
- Western blot [8]
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Validation data
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- Product number
- NB300-221 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB300-221, RRID:AB_10077627
- Product name
- Mouse Monoclonal GAPDH Antibody
- Antibody type
- Monoclonal
- Description
- Immunogen affinity purified.
- Reactivity
- Human, Mouse, Rat, Bovine, Canine, Chicken/Avian, Feline, Hamster, Porcine, Rabbit, Sheep, Simian, Zebrafish
- Host
- Mouse
- Isotype
- IgM
- Vial size
- 0.1 ml
- Concentration
- 1.0 mg/ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references Ferryl Hemoglobin Inhibits Osteoclastic Differentiation of Macrophages in Hemorrhaged Atherosclerotic Plaques.
The extracellular signal-regulated kinase 1/2 modulates the intracellular localization of DNA methyltransferase 3A to regulate erythrocytic differentiation.
Higher proteotoxic stress rather than mitochondrial damage is involved in higher neurotoxicity of bortezomib compared to carfilzomib.
Bicalutamide Elicits Renal Damage by Causing Mitochondrial Dysfunction via ROS Damage and Upregulation of HIF-1.
Muscle from grass- and grain-fed cattle differs energetically.
A nicotinamide phosphoribosyltransferase-GAPDH interaction sustains the stress-induced NMN/NAD(+) salvage pathway in the nucleus.
Neurokinin-1 Receptor Signaling Is Required for Efficient Ca2+ Flux in T-Cell-Receptor-Activated T Cells.
FADD and Caspase-8 Regulate Gut Homeostasis and Inflammation by Controlling MLKL- and GSDMD-Mediated Death of Intestinal Epithelial Cells.
Microglial depletion prevents extracellular matrix changes and striatal volume reduction in a model of Huntington's disease.
The microglial NLRP3 inflammasome is activated by amyotrophic lateral sclerosis proteins.
Hydrogen sulfide inhibits calcification of heart valves; implications for calcific aortic valve disease.
Dynamics of sphingolipids and the serine palmitoyltransferase complex in rat oligodendrocytes during myelination.
Z-nucleic-acid sensing triggers ZBP1-dependent necroptosis and inflammation.
Autophosphorylation at serine 166 regulates RIP kinase 1-mediated cell death and inflammation.
Diverse Consequences in Liver Injury in Mice with Different Autophagy Functional Status Treated with Alcohol.
Nucleus pulposus primary cilia alter their length in response to changes in extracellular osmolarity but do not control TonEBP-mediated osmoregulation.
Patient-derived organoids (PDOs) as a novel in vitro model for neuroblastoma tumours.
Modulation of Cathepsin L Expression in the Coronary Arteries of Atherosclerotic Swine.
Defective fibrin deposition and thrombus stability in Bambi-/- mice are mediated by elevated anticoagulant function.
Protein tyrosine phosphatase receptor type R (PTPRR) antagonizes the Wnt signaling pathway in ovarian cancer by dephosphorylating and inactivating β-catenin.
The impact of obesity on brain iron levels and α-synuclein expression is regionally dependent.
Effects of non-euphoric plant cannabinoids on muscle quality and performance of dystrophic mdx mice.
Transcriptomics Analysis Reveals New Insights into the Roles of Notch1 Signaling on Macrophage Polarization.
Mesenchymal Stromal Cells Are Required for Regeneration and Homeostatic Maintenance of Skeletal Muscle.
Investigating the effects of Pirfenidone on TGF-β1 stimulated non-SMAD signaling pathways in Dupuytren's disease -derived fibroblasts.
A20 prevents inflammasome-dependent arthritis by inhibiting macrophage necroptosis through its ZnF7 ubiquitin-binding domain.
A novel motif in the proximal C-terminus of Pannexin 1 regulates cell surface localization.
p53 mutant-type in human prostate cancer cells determines the sensitivity to phenethyl isothiocyanate induced growth inhibition.
Time series modeling of cell cycle exit identifies Brd4 dependent regulation of cerebellar neurogenesis.
CCL2 induces resistance to the antiproliferative effect of cabazitaxel in prostate cancer cells.
Extracellular vesicles secreted by hypoxia pre-challenged mesenchymal stem cells promote non-small cell lung cancer cell growth and mobility as well as macrophage M2 polarization via miR-21-5p delivery.
C1q/TNF-related protein-9 attenuates atherosclerosis through AMPK-NLRP3 inflammasome singling pathway.
Synthesis and Application of an Activity-Based Peptide-Peptoid Hybrid Probe for the Immunoproteasome.
Tumor-Associated Macrophages Induce Migration of Renal Cell Carcinoma Cells via Activation of the CCL20-CCR6 Axis.
Transcriptomic profiling of trophoblast fusion using BeWo and JEG-3 cell lines.
Stress-induced phospho-ubiquitin formation causes parkin degradation.
Coffee diterpenes kahweol acetate and cafestol synergistically inhibit the proliferation and migration of prostate cancer cells.
Targeting the phosphorylation site of myristoylated alanine-rich C kinase substrate alleviates symptoms in a murine model of steroid-resistant asthma.
Hydrogen Sulfide Abrogates Hemoglobin-Lipid Interaction in Atherosclerotic Lesion.
Altered downstream target gene expression of the placental Vitamin D receptor in human idiopathic fetal growth restriction.
Dynamic MTORC1-TFEB feedback signaling regulates hepatic autophagy, steatosis and liver injury in long-term nutrient oversupply.
Loss of Axon Bifurcation in Mesencephalic Trigeminal Neurons Impairs the Maximal Biting Force in Npr2-Deficient Mice.
The Absence of Sensory Axon Bifurcation Affects Nociception and Termination Fields of Afferents in the Spinal Cord.
FANCC localizes with UNC5A at neurite outgrowth and promotes neuritogenesis.
Proteomic analysis of the hypothalamus of broiler-type Taiwan country chickens in response to acute heat stress.
Annotation of differential protein expression in the hypothalami of layer-type Taiwan country chickens in response to acute heat stress.
AngII induces HepG2 cells to activate epithelial-mesenchymal transition.
Tumor necrosis factor-α induces prostate cancer cell migration in lymphatic metastasis through CCR7 upregulation.
C-C motif ligand 5 promotes migration of prostate cancer cells in the prostate cancer bone metastasis microenvironment.
TRIM11 activates the proteasome and promotes overall protein degradation by regulating USP14.
Downregulation of tight junction protein zonula occludens-2 and urothelium damage in a cyclophosphamide-induced mouse model of cystitis.
COX-2 expression mediated by calcium-TonEBP signaling axis under hyperosmotic conditions serves osmoprotective function in nucleus pulposus cells.
Histone H3K27 methylation modulates the dynamics of FANCD2 on chromatin to facilitate NHEJ and genome stability.
Pathogenic mutation in the ALS/FTD gene, CCNF, causes elevated Lys48-linked ubiquitylation and defective autophagy.
Osteopontin-integrin engagement induces HIF-1α-TCF12-mediated endothelial-mesenchymal transition to exacerbate colorectal cancer.
Complement C5a receptors C5L2 and C5aR in renal fibrosis.
Laser acupuncture-induced analgesic effect and molecular alterations in an incision pain model: a comparison with electroacupuncture-induced effects.
The IgCAM CLMP regulates expression of Connexin43 and Connexin45 in intestinal and ureteral smooth muscle contraction in mice.
Serum retinol-binding protein-induced endothelial inflammation is mediated through the activation of toll-like receptor 4.
Effects of Electroacupuncture on Methamphetamine-Induced Behavioral Changes in Mice.
Toxicological effects of NCKU-21, a phenanthrene derivative, on cell growth and migration of A549 and CL1-5 human lung adenocarcinoma cells.
Characterization of a panel of monoclonal antibodies recognizing specific epitopes on GFAP.
Object Phobia and Altered RhoA Signaling in Amygdala of Mice Lacking RICH2.
Regulation of Focal Adhesion Kinase through a Direct Interaction with an Endogenous Inhibitor.
The cytoplasmic nuclear receptor RARγ controls RIP1 initiated cell death when cIAP activity is inhibited.
CRISPR-Mediated Base Editing Enables Efficient Disruption of Eukaryotic Genes through Induction of STOP Codons.
Stabilization of F-actin by tropomyosin isoforms regulates the morphology and mechanical behavior of red blood cells.
Local cellular neighborhood controls proliferation in cell competition.
Characterization of epithelial-mesenchymal transition intermediate/hybrid phenotypes associated to resistance to EGFR inhibitors in non-small cell lung cancer cell lines.
Editor's Highlight: Pregnancy Alters Aflatoxin B1 Metabolism and Increases DNA Damage in Mouse Liver.
Early cerebellar deficits in mitochondrial biogenesis and respiratory chain complexes in the KIKO mouse model of Friedreich ataxia.
ERK signaling is required for VEGF-A/VEGFR2-induced differentiation of porcine adipose-derived mesenchymal stem cells into endothelial cells.
DNA damage during S-phase mediates the proliferation-quiescence decision in the subsequent G1 via p21 expression.
Actin cortex architecture regulates cell surface tension.
The mTOR Substrate S6 Kinase 1 (S6K1) Is a Negative Regulator of Axon Regeneration and a Potential Drug Target for Central Nervous System Injury.
Multiparametric Analysis of Cell Shape Demonstrates that β-PIX Directly Couples YAP Activation to Extracellular Matrix Adhesion.
HTR-8/SVneo cell line contains a mixed population of cells.
VAPs and ACBD5 tether peroxisomes to the ER for peroxisome maintenance and lipid homeostasis.
Tumor-associated macrophages promote prostate cancer migration through activation of the CCL22-CCR4 axis.
MMP-13 deletion decreases profibrogenic molecules and attenuates N-nitrosodimethylamine-induced liver injury and fibrosis in mice.
YB-1 orchestrates onset and resolution of renal inflammation via IL10 gene regulation.
Chondromodulin‑I suppresses tumorigenesis of human osteosarcoma cells.
Alternative Polyadenylation of PRELID1 Regulates Mitochondrial ROS Signaling and Cancer Outcomes.
Human Astrocytes Transfer Aggregated Alpha-Synuclein via Tunneling Nanotubes.
Early VGLUT1-specific parallel fiber synaptic deficits and dysregulated cerebellar circuit in the KIKO mouse model of Friedreich ataxia.
16-Hydroxycleroda-3, 13-dien-15, 16-olide inhibits the proliferation and induces mitochondrial-dependent apoptosis through Akt, mTOR, and MEK-ERK pathways in human renal carcinoma cells.
Keratin 8/18 regulation of insulin receptor signaling and trafficking in hepatocytes through a concerted phosphoinositide-dependent Akt and Rab5 modulation.
Timing of Smarcb1 and Nf2 inactivation determines schwannoma versus rhabdoid tumor development.
A promising protein responsible for overactive bladder in ovariectomized mice.
Vitamin D controls resistance artery function through regulation of perivascular adipose tissue hypoxia and inflammation.
PKA inhibits WNT signalling in adrenal cortex zonation and prevents malignant tumour development.
Beneficial effects of increased lysozyme levels in Alzheimer's disease modelled in Drosophila melanogaster.
Endogenous DNA Damage Leads to p53-Independent Deficits in Replicative Fitness in Fetal Murine Fancd2-/- Hematopoietic Stem and Progenitor Cells.
11,12-Epoxyecosatrienoic acids mitigate endothelial dysfunction associated with estrogen loss and aging: Role of membrane depolarization.
PIAS1 Regulates Mutant Huntingtin Accumulation and Huntington's Disease-Associated Phenotypes In Vivo.
High mobility group box 1-induced epithelial mesenchymal transition in human airway epithelial cells.
Patterning of Fibroblast and Matrix Anisotropy within 3D Confinement is Driven by the Cytoskeleton.
Rho-associated kinase (ROCK) function is essential for cell cycle progression, senescence and tumorigenesis.
Hypomorphic mutations in TRNT1 cause retinitis pigmentosa with erythrocytic microcytosis.
Pharmacological induction of ferritin prevents osteoblastic transformation of smooth muscle cells.
Differentiation of porcine mesenchymal stem cells into epithelial cells as a potential therapeutic application to facilitate epithelial regeneration.
Keap1/Nrf2 pathway activation leads to a repressed hepatic gluconeogenic and lipogenic program in mice on a high-fat diet.
The multi-target effects of CNI-1493: convergence of anti-amylodogenic and anti-inflammatory properties in animal models of Alzheimer's disease.
Withaferin A induces Nrf2-dependent protection against liver injury: Role of Keap1-independent mechanisms.
Differential cytokine sensitivities of STAT5-dependent enhancers rely on Stat5 autoregulation.
Guanylate Binding Protein (GBP) 5 Is an Interferon-Inducible Inhibitor of HIV-1 Infectivity.
Notch1 Regulates Hippocampal Plasticity Through Interaction with the Reelin Pathway, Glutamatergic Transmission and CREB Signaling.
Status of autophagy, lysosome activity and apoptosis during corpus luteum regression in cattle.
Atherogenic Cytokines Regulate VEGF-A-Induced Differentiation of Bone Marrow-Derived Mesenchymal Stem Cells into Endothelial Cells.
Monocytic Tissue Transglutaminase in a Rat Model for Reversible Acute Rejection and Chronic Renal Allograft Injury.
Assembly and interrogation of Alzheimer's disease genetic networks reveal novel regulators of progression.
MET Gene Amplification and MET Receptor Activation Are Not Sufficient to Predict Efficacy of Combined MET and EGFR Inhibitors in EGFR TKI-Resistant NSCLC Cells.
Down-regulation of hsa-miR-1264 contributes to DNMT1-mediated silencing of SOCS3.
Bub1 autophosphorylation feeds back to regulate kinetochore docking and promote localized substrate phosphorylation.
Notch signaling in response to excitotoxicity induces neurodegeneration via erroneous cell cycle reentry.
Attenuation of acute rat renal allograft rejection by apolipoprotein E-mimetic Peptide.
Post-transcriptional inactivation of matrix metalloproteinase-12 after focal cerebral ischemia attenuates brain damage.
A chemical genetics approach for the functional assessment of novel cancer genes.
Evidence for a functional vasodilatatory role for hydrogen sulphide in the human cutaneous microvasculature.
Prolyl-4-hydroxylase domain protein 2 controls NF-κB/p65 transactivation and enhances the catabolic effects of inflammatory cytokines on cells of the nucleus pulposus.
Antiallodynic effects of alpha lipoic acid in an optimized RR-EAE mouse model of MS-neuropathic pain are accompanied by attenuation of upregulated BDNF-TrkB-ERK signaling in the dorsal horn of the spinal cord.
Loss of Androgen-Regulated MicroRNA 1 Activates SRC and Promotes Prostate Cancer Bone Metastasis.
Enolase is regulated by Liver X Receptors.
Neutralizing anti-interleukin-1β antibodies modulate fetal blood-brain barrier function after ischemia.
Synergistic effect of angiotensin II on vascular endothelial growth factor-A-mediated differentiation of bone marrow-derived mesenchymal stem cells into endothelial cells.
MicroRNA miR145 regulates TGFBR2 expression and matrix synthesis in vascular smooth muscle cells.
Xylosyltransferase-1 expression is refractory to inhibition by the inflammatory cytokines tumor necrosis factor α and IL-1β in nucleus pulposus cells: novel regulation by AP-1, Sp1, and Sp3.
The Roles of Tight Junctions and Claudin-1 in the Microbubble-Mediated Ultrasound-Induced Enhancement of Drug Concentrations in Rat Prostate.
Tropomodulin 1 directly controls thin filament length in both wild-type and tropomodulin 4-deficient skeletal muscle.
Functional constituents of a local serotonergic system, intrinsic to the human coronary artery smooth muscle cells.
Systems Analyses Reveal Shared and Diverse Attributes of Oct4 Regulation in Pluripotent Cells.
Force transmission during adhesion-independent migration.
Effect of obesity and exercise on the expression of the novel myokines, Myonectin and Fibronectin type III domain containing 5.
Selenite cataracts: activation of endoplasmic reticulum stress and loss of Nrf2/Keap1-dependent stress protection.
Tumor necrosis factor-α- and interleukin-1β-dependent matrix metalloproteinase-3 expression in nucleus pulposus cells requires cooperative signaling via syndecan 4 and mitogen-activated protein kinase-NF-κB axis: implications in inflammatory disc disease.
HEK-293 cells expressing the cystic fibrosis transmembrane conductance regulator (CFTR): a model for studying regulation of Cl- transport.
The PSD protein ProSAP2/Shank3 displays synapto-nuclear shuttling which is deregulated in a schizophrenia-associated mutation.
Calpain-mediated proteolysis of tropomodulin isoforms leads to thin filament elongation in dystrophic skeletal muscle.
Cyclin e1 regulates Kv2.1 channel phosphorylation and localization in neuronal ischemia.
Genetic or pharmacologic activation of Nrf2 signaling fails to protect against aflatoxin genotoxicity in hypersensitive GSTA3 knockout mice.
Methylglyoxal induces endoplasmic reticulum stress and DNA demethylation in the Keap1 promoter of human lens epithelial cells and age-related cataracts.
Pen-2 is essential for γ-secretase complex stability and trafficking but partially dispensable for endoproteolysis.
Changes in protein expression in testes of L2 strain Taiwan country chickens in response to acute heat stress.
TGF-β promotes glioma cell growth via activating Nodal expression through Smad and ERK1/2 pathways.
Temporal regulation of apoptotic and anti-apoptotic molecules after middle cerebral artery occlusion followed by reperfusion.
Tumor microenvironment-associated modifications of alternative splicing.
Alanine repeats influence protein localization in splicing speckles and paraspeckles.
Arsenic inhibits hedgehog signaling during P19 cell differentiation.
Rare GATA5 sequence variants identified in individuals with bicuspid aortic valve.
Stem cell treatment after cerebral ischemia regulates the gene expression of apoptotic molecules.
Syntaxin-binding domain of Kv2.1 is essential for the expression of apoptotic K+ currents.
Calcineurin-mediated YB-1 dephosphorylation regulates CCL5 expression during monocyte differentiation.
Exercise, vascular stiffness, and tissue transglutaminase.
Monoubiquitination of ancient ubiquitous protein 1 promotes lipid droplet clustering.
Structural analysis of microRNA-target interaction by sequential seed mutagenesis and stem-loop 3' RACE.
Atherogenesis may involve the prooxidant and proinflammatory effects of ferryl hemoglobin.
Shared and cell type-specific mitochondrial defects and metabolic adaptations in primary cells from PINK1-deficient mice.
Serum from minimal change patients in relapse increases CD80 expression in cultured podocytes.
Increased tissue transglutaminase activity contributes to central vascular stiffness in eNOS knockout mice.
YB-1 is an early and central mediator of bacterial and sterile inflammation in vivo.
The performance of an orthosilicic acid-releasing silica gel fiber fleece in wound healing.
Focal adhesion kinase mediates β-catenin signaling in periodontal ligament cells.
Zyxin cooperates with PTOV1 to confer retinoic acid resistance by repressing RAR activity.
Tumor necrosis factor α- and interleukin-1β-dependent induction of CCL3 expression by nucleus pulposus cells promotes macrophage migration through CCR1.
Expression and biologic significance of adiponectin receptors in papillary thyroid carcinoma.
Knockdown of GPC3 inhibits the proliferation of Huh7 hepatocellular carcinoma cells through down-regulation of YAP.
SOCS3 promotor hypermethylation and STAT3-NF-κB interaction downregulate SOCS3 expression in human coronary artery smooth muscle cells.
Inflammatory cytokines associated with degenerative disc disease control aggrecanase-1 (ADAMTS-4) expression in nucleus pulposus cells through MAPK and NF-κB.
Inflammatory cytokines induce NOTCH signaling in nucleus pulposus cells: implications in intervertebral disc degeneration.
Endothelial nitric oxide signaling regulates Notch1 in aortic valve disease.
O-GlcNAcylation of αB-crystallin regulates its stress-induced translocation and cytoprotection.
Factors controlling nascent high-density lipoprotein particle heterogeneity: ATP-binding cassette transporter A1 activity and cell lipid and apolipoprotein AI availability.
Reciprocal regulation of p53 and malic enzymes modulates metabolism and senescence.
A novel cell-penetrating peptide TAT-A1 delivers siRNA into tumor cells selectively.
The six amino acid antimicrobial peptide bLFcin6 penetrates cells and delivers siRNA.
A genome-wide RNAi screen identifies proteins modulating aberrant FLT3-ITD signaling.
Alternative polyadenylation and miR-34 family members regulate tau expression.
The terminal pathway of the complement system is activated in focal penetrating but not in mild diffuse traumatic brain injury.
GogB is an anti-inflammatory effector that limits tissue damage during Salmonella infection through interaction with human FBXO22 and Skp1.
Tmod1 and CP49 synergize to control the fiber cell geometry, transparency, and mechanical stiffness of the mouse lens.
HIF-1α contributes to hypoxia-induced invasion and metastasis of esophageal carcinoma via inhibiting E-cadherin and promoting MMP-2 expression.
Contractile Activity Regulates Inducible Nitric Oxide Synthase Expression and NO(i) Production in Cardiomyocytes via a FAK-Dependent Signaling Pathway.
Arsenic exposure inhibits myogenesis and neurogenesis in P19 stem cells through repression of the β-catenin signaling pathway.
Age-related cataracts: homocysteine coupled endoplasmic reticulum stress and suppression of Nrf2-dependent antioxidant protection.
Notch-3 receptor activation drives inflammation and fibrosis following tubulointerstitial kidney injury.
Genetic deletion of RALA and RALB small GTPases reveals redundant functions in development and tumorigenesis.
Platelet lysate suppresses the expression of lipocalin-type prostaglandin D2 synthase that positively controls adipogenic differentiation of human mesenchymal stromal cells.
Histone deacetylase inhibition facilitates GM-CSF-mediated expansion of myeloid-derived suppressor cells in vitro and in vivo.
Differential response of arterial and venous endothelial cells to extracellular matrix is modulated by oxygen.
A high-throughput FRET-based assay for determination of Atg4 activity.
IL-27 production and STAT3-dependent upregulation of B7-H1 mediate immune regulatory functions of liver plasmacytoid dendritic cells.
PINK1 enhances insulin-like growth factor-1-dependent Akt signaling and protection against apoptosis.
Integrin α9β1-mediated cell migration in glioblastoma via SSAT and Kir4.2 potassium channel pathway.
Reduced expression of UGT1A1 in intestines of humanized UGT1 mice via inactivation of NF-κB leads to hyperbilirubinemia.
A high calcium diet containing nonfat dry milk reduces weight gain and associated adipose tissue inflammation in diet-induced obese mice when compared to high calcium alone.
Identification of potential markers related to neoadjuvant chemotherapy sensitivity of breast cancer by SELDI-TOF MS.
Thin-filament length correlates with fiber type in human skeletal muscle.
Proliferation and differentiation of osteoblastic cells on silicon-doped TiO(2) film deposited by cathodic arc.
Retinol-binding protein 4 induces inflammation in human endothelial cells by an NADPH oxidase- and nuclear factor kappa B-dependent and retinol-independent mechanism.
Chronic central administration of valproic acid: Increased pro-survival phospho-proteins and growth cone associated proteins with no behavioral pathology.
CDK5 regulatory subunit-associated protein 1-like 1 (CDKAL1) is a tail-anchored protein in the endoplasmic reticulum (ER) of insulinoma cells.
Ischemia-reperfusion impairs blood-brain barrier function and alters tight junction protein expression in the ovine fetus.
The Ca(v)3.1 T-type calcium channel is required for neointimal formation in response to vascular injury in mice.
Down-regulation of calcium/calmodulin-dependent protein kinase kinase 2 by androgen deprivation induces castration-resistant prostate cancer.
Reovirus exerts potent oncolytic effects in head and neck cancer cell lines that are independent of signalling in the EGFR pathway.
Cigarette smoke induces MUC5AC protein expression through the activation of Sp1.
Altered mTOR signaling and enhanced CYFIP2 expression levels in subjects with fragile X syndrome.
Low glucose under hypoxic conditions induces unfolded protein response and produces reactive oxygen species in lens epithelial cells.
The metastasis gene NEDD9 product acts through integrin β3 and Src to promote mesenchymal motility and inhibit amoeboid motility.
Cell-cell contact preserves cell viability via plakoglobin.
Identification of hnRNPH1, NF45, and C14orf166 as novel host interacting partners of the mature hepatitis C virus core protein.
p53 target Siva regulates apoptosis in ischemic kidneys.
Human neuroglobin functions as a redox-regulated nitrite reductase.
RAD21 cooperates with pluripotency transcription factors in the maintenance of embryonic stem cell identity.
Prostate epithelial Pten/TP53 loss leads to transformation of multipotential progenitors and epithelial to mesenchymal transition.
Elevated levels of uterine anti-apoptotic signaling may activate NFKB and potentially confer resistance to caspase 3-mediated apoptotic cell death during pregnancy in mice.
Latent membrane protein 1 of Epstein-Barr virus regulates death-associated protein kinase 1 in lymphoblastoid cell line.
Phosphodiesterase 10A upregulation contributes to pulmonary vascular remodeling.
The pattern of expression of guanine nucleotide-binding protein beta3 in the retina is conserved across vertebrate species.
MicroRNA-200 family members differentially regulate morphological plasticity and mode of melanoma cell invasion.
Iris pigment epithelial cells express a functional lipopolysaccharide receptor complex.
NHE3 function and phosphorylation are regulated by a calyculin A-sensitive phosphatase.
Role of androgens and the androgen receptor in epithelial-mesenchymal transition and invasion of prostate cancer cells.
Regulation of vascular endothelial growth factor-induced endothelial cell migration by LIM kinase 1-mediated phosphorylation of annexin 1.
Role of mouse hepatitis virus (MHV) receptor murine CEACAM1 in the resistance of mice to MHV infection: studies of mice with chimeric mCEACAM1a and mCEACAM1b.
Skeletal muscle NAMPT is induced by exercise in humans.
Pannexin 2 is expressed by postnatal hippocampal neural progenitors and modulates neuronal commitment.
Arginase inhibition restores NOS coupling and reverses endothelial dysfunction and vascular stiffness in old rats.
The proteasome is an integral part of solar ultraviolet a radiation-induced gene expression.
Expression and activity of phosphodiesterase isoforms during epithelial mesenchymal transition: the role of phosphodiesterase 4.
Correlation of human leukocyte antigen-G (HLA-G) expression and disease progression in epithelial ovarian cancer.
A UV-responsive internal ribosome entry site enhances serine hydroxymethyltransferase 1 expression for DNA damage repair.
Mechanism of the internal ribosome entry site-mediated translation of serine hydroxymethyltransferase 1.
Clathrin-independent internalization of normal cellular prion protein in neuroblastoma cells is associated with the Arf6 pathway.
A genome-scale RNAi screen for Oct4 modulators defines a role of the Paf1 complex for embryonic stem cell identity.
Interleukin-13-induced MUC5AC is regulated by 15-lipoxygenase 1 pathway in human bronchial epithelial cells.
OSBP-related protein 2 is a sterol receptor on lipid droplets that regulates the metabolism of neutral lipids.
Argininosuccinate synthetase is a functional target for a snake venom anti-hypertensive peptide: role in arginine and nitric oxide production.
PARP-1 inhibits glycolysis in ischemic kidneys.
Mthfd1 is an essential gene in mice and alters biomarkers of impaired one-carbon metabolism.
The hemopexin domain of MMP-9 inhibits angiogenesis and retards the growth of intracranial glioblastoma xenograft in nude mice.
Migfilin interacts with Src and contributes to cell-matrix adhesion-mediated survival signaling.
Crude subcellular fractionation of cultured mammalian cell lines.
Intravesical combination treatment with antisense oligonucleotides targeting heat shock protein-27 and HTI-286 as a novel strategy for high-grade bladder cancer.
Fumarate hydratase deficiency in renal cancer induces glycolytic addiction and hypoxia-inducible transcription factor 1alpha stabilization by glucose-dependent generation of reactive oxygen species.
Transcriptional restriction of human immunodeficiency virus type 1 gene expression in undifferentiated primary monocytes.
A Golgi-associated protein 4.1B variant is required for assimilation of proteins in the membrane.
Antileukemia effects of xanthohumol in Bcr/Abl-transformed cells involve nuclear factor-kappaB and p53 modulation.
PTEN-deficient cancers depend on PIK3CB.
Glycogen synthase kinase 3beta regulates cell death induced by synthetic triterpenoids.
The extensive nitration of neurofilament light chain in the hippocampus is associated with the cognitive impairment induced by amyloid beta in mice.
RNAi-mediated silencing of nuclear factor erythroid-2-related factor 2 gene expression in non-small cell lung cancer inhibits tumor growth and increases efficacy of chemotherapy.
Combined tyrosine and serine/threonine kinase inhibition by sorafenib prevents progression of experimental pulmonary hypertension and myocardial remodeling.
Plakophilin 2: a critical scaffold for PKC alpha that regulates intercellular junction assembly.
Tempol protects against oxidative damage and delays epithelial tumor onset in Fanconi anemia mice.
Signaling pathways modulated by fish oil in salt-sensitive hypertension.
Tissue inhibitor of metalloproteinase 3 suppresses tumor angiogenesis in matrix metalloproteinase 2-down-regulated lung cancer.
Metastatic susceptibility locus, an 8p hot-spot for tumour progression disrupted in colorectal liver metastases: 13 candidate genes examined at the DNA, mRNA and protein level.
IL-1beta-driven ST2L expression promotes maturation resistance in rapamycin-conditioned dendritic cells.
IL-1beta-driven ST2L expression promotes maturation resistance in rapamycin-conditioned dendritic cells.
PINCH-1 regulates the ERK-Bim pathway and contributes to apoptosis resistance in cancer cells.
Zag expression during aging suppresses proliferation after kidney injury.
The complement factor C5a contributes to pathology in a rat model of amyotrophic lateral sclerosis.
The complement factor C5a contributes to pathology in a rat model of amyotrophic lateral sclerosis.
uPAR promotes formation of the p130Cas-Crk complex to activate Rac through DOCK180.
Cardiomyocyte apoptosis in autoimmune cardiomyopathy: mediated via endoplasmic reticulum stress and exaggerated by norepinephrine.
CD200 and its receptor, CD200R, modulate bone mass via the differentiation of osteoclasts.
Metformin transport by a newly cloned proton-stimulated organic cation transporter (plasma membrane monoamine transporter) expressed in human intestine.
A ferritin-responsive internal ribosome entry site regulates folate metabolism.
Cdc42-interacting protein-4 functionally links actin and microtubule networks at the cytolytic NK cell immunological synapse.
2-amino-N-{4-[5-(2-phenanthrenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-phenyl} acetamide (OSU-03012), a celecoxib derivative, directly targets p21-activated kinase.
Estrogen effects on skeletal muscle insulin-like growth factor 1 and myostatin in ovariectomized rats.
NAD(P)H oxidases regulate HIF-2alpha protein expression.
Allelic variation in the hepatitis C virus NS4B protein dramatically influences RNA replication.
Potentiation of insulin-stimulated glucose transport by the AMP-activated protein kinase.
Membrane localization and pH-dependent transport of a newly cloned organic cation transporter (PMAT) in kidney cells.
Apoptotic surge of potassium currents is mediated by p38 phosphorylation of Kv2.1.
Increased insulin sensitivity and maintenance of glucose utilization rates in fetal sheep with placental insufficiency and intrauterine growth restriction.
Heat-killed BCG induces biphasic cyclooxygenase 2+ splenic macrophage formation--role of IL-10 and bone marrow precursors.
Activation of endoplasmic reticulum stress response during the development of ischemic heart disease.
Pluronic L81 enhances triacylglycerol accumulation in the cytosol and inhibits chylomicron secretion.
Dimethyl sulfoxide has an impact on epigenetic profile in mouse embryoid body.
Developmental changes in ovine myocardial glucose transporters and insulin signaling following hyperthermia-induced intrauterine fetal growth restriction.
Developmental changes in ovine myocardial glucose transporters and insulin signaling following hyperthermia-induced intrauterine fetal growth restriction.
Mitogen-activated protein kinases control cardiac KChIP2 gene expression.
The differentiation-dependent desmosomal cadherin desmoglein 1 is a novel caspase-3 target that regulates apoptosis in keratinocytes.
Phosphorylation of focal adhesion kinase (FAK) on Ser732 is induced by rho-dependent kinase and is essential for proline-rich tyrosine kinase-2-mediated phosphorylation of FAK on Tyr407 in response to vascular endothelial growth factor.
Automated quantification tool for high-throughput proteomics using stable isotope labeling and LC-MSn.
Reversal of RNA missplicing and myotonia after muscleblind overexpression in a mouse poly(CUG) model for myotonic dystrophy.
Inhibition of apoptosis by P2Y2 receptor activation: novel pathways for neuronal survival.
High-throughput identification of IMCD proteins using LC-MS/MS.
Increased susceptibility to transcriptional changes with novel stressor in adrenal medulla of rats exposed to prolonged cold stress.
Regulation of endothelial argininosuccinate synthase expression and NO production by an upstream open reading frame.
Desmoplakin assembly dynamics in four dimensions: multiple phases differentially regulated by intermediate filaments and actin.
Differential regulation of the cell cycle by alpha1-adrenergic receptor subtypes.
Prognostic significance of a short sequence insertion in the MCL-1 promoter in chronic lymphocytic leukemia.
Prognostic significance of a short sequence insertion in the MCL-1 promoter in chronic lymphocytic leukemia.
Cathepsin B mRNA and protein expression following contusion spinal cord injury in rats.
Cathepsin B mRNA and protein expression following contusion spinal cord injury in rats.
Myocardial cell death and regeneration during progression of cardiac hypertrophy to heart failure.
Brain-specific deletion of neuropathy target esterase/swisscheese results in neurodegeneration.
Emerging role for autophagy in the removal of aggresomes in Schwann cells.
Interference of hepatitis C virus RNA replication by short interfering RNAs.
Zavaczki E, Gáll T, Zarjou A, Hendrik Z, Potor L, Tóth CZ, Méhes G, Gyetvai Á, Agarwal A, Balla G, Balla J
Oxidative medicine and cellular longevity 2020;2020:3721383
Oxidative medicine and cellular longevity 2020;2020:3721383
The extracellular signal-regulated kinase 1/2 modulates the intracellular localization of DNA methyltransferase 3A to regulate erythrocytic differentiation.
Tu PS, Lin EC, Chen HW, Chen SW, Lin TA, Gau JP, Chang YI
American journal of translational research 2020;12(3):1016-1030
American journal of translational research 2020;12(3):1016-1030
Higher proteotoxic stress rather than mitochondrial damage is involved in higher neurotoxicity of bortezomib compared to carfilzomib.
Jannuzzi AT, Arslan S, Yilmaz AM, Sari G, Beklen H, Méndez L, Fedorova M, Arga KY, Karademir Yilmaz B, Alpertunga B
Redox biology 2020 May;32:101502
Redox biology 2020 May;32:101502
Bicalutamide Elicits Renal Damage by Causing Mitochondrial Dysfunction via ROS Damage and Upregulation of HIF-1.
Chen KC, Chen CR, Chen CY, Tzou KY, Peng CC, Peng RY
International journal of molecular sciences 2020 May 11;21(9)
International journal of molecular sciences 2020 May 11;21(9)
Muscle from grass- and grain-fed cattle differs energetically.
Apaoblaza A, Gerrard SD, Matarneh SK, Wicks JC, Kirkpatrick L, England EM, Scheffler TL, Duckett SK, Shi H, Silva SL, Grant AL, Gerrard DE
Meat science 2020 Mar;161:107996
Meat science 2020 Mar;161:107996
A nicotinamide phosphoribosyltransferase-GAPDH interaction sustains the stress-induced NMN/NAD(+) salvage pathway in the nucleus.
Grolla AA, Miggiano R, Di Marino D, Bianchi M, Gori A, Orsomando G, Gaudino F, Galli U, Del Grosso E, Mazzola F, Angeletti C, Guarneri M, Torretta S, Calabrò M, Boumya S, Fan X, Colombo G, Travelli C, Rocchio F, Aronica E, Wohlschlegel JA, Deaglio S, Rizzi M, Genazzani AA, Garavaglia S
The Journal of biological chemistry 2020 Mar 13;295(11):3635-3651
The Journal of biological chemistry 2020 Mar 13;295(11):3635-3651
Neurokinin-1 Receptor Signaling Is Required for Efficient Ca2+ Flux in T-Cell-Receptor-Activated T Cells.
Morelli AE, Sumpter TL, Rojas-Canales DM, Bandyopadhyay M, Chen Z, Tkacheva O, Shufesky WJ, Wallace CT, Watkins SC, Berger A, Paige CJ, Falo LD Jr, Larregina AT
Cell reports 2020 Mar 10;30(10):3448-3465.e8
Cell reports 2020 Mar 10;30(10):3448-3465.e8
FADD and Caspase-8 Regulate Gut Homeostasis and Inflammation by Controlling MLKL- and GSDMD-Mediated Death of Intestinal Epithelial Cells.
Schwarzer R, Jiao H, Wachsmuth L, Tresch A, Pasparakis M
Immunity 2020 Jun 16;52(6):978-993.e6
Immunity 2020 Jun 16;52(6):978-993.e6
Microglial depletion prevents extracellular matrix changes and striatal volume reduction in a model of Huntington's disease.
Crapser JD, Ochaba J, Soni N, Reidling JC, Thompson LM, Green KN
Brain : a journal of neurology 2020 Jan 1;143(1):266-288
Brain : a journal of neurology 2020 Jan 1;143(1):266-288
The microglial NLRP3 inflammasome is activated by amyotrophic lateral sclerosis proteins.
Deora V, Lee JD, Albornoz EA, McAlary L, Jagaraj CJ, Robertson AAB, Atkin JD, Cooper MA, Schroder K, Yerbury JJ, Gordon R, Woodruff TM
Glia 2020 Feb;68(2):407-421
Glia 2020 Feb;68(2):407-421
Hydrogen sulfide inhibits calcification of heart valves; implications for calcific aortic valve disease.
Sikura KÉ, Potor L, Szerafin T, Oros M, Nagy P, Méhes G, Hendrik Z, Zarjou A, Agarwal A, Posta N, Torregrossa R, Whiteman M, Fürtös I, Balla G, Balla J
British journal of pharmacology 2020 Feb;177(4):793-809
British journal of pharmacology 2020 Feb;177(4):793-809
Dynamics of sphingolipids and the serine palmitoyltransferase complex in rat oligodendrocytes during myelination.
Davis DL, Mahawar U, Pope VS, Allegood J, Sato-Bigbee C, Wattenberg BW
Journal of lipid research 2020 Apr;61(4):505-522
Journal of lipid research 2020 Apr;61(4):505-522
Z-nucleic-acid sensing triggers ZBP1-dependent necroptosis and inflammation.
Jiao H, Wachsmuth L, Kumari S, Schwarzer R, Lin J, Eren RO, Fisher A, Lane R, Young GR, Kassiotis G, Kaiser WJ, Pasparakis M
Nature 2020 Apr;580(7803):391-395
Nature 2020 Apr;580(7803):391-395
Autophosphorylation at serine 166 regulates RIP kinase 1-mediated cell death and inflammation.
Laurien L, Nagata M, Schünke H, Delanghe T, Wiederstein JL, Kumari S, Schwarzer R, Corona T, Krüger M, Bertrand MJM, Kondylis V, Pasparakis M
Nature communications 2020 Apr 8;11(1):1747
Nature communications 2020 Apr 8;11(1):1747
Diverse Consequences in Liver Injury in Mice with Different Autophagy Functional Status Treated with Alcohol.
Yan S, Zhou J, Chen X, Dong Z, Yin XM
The American journal of pathology 2019 Sep;189(9):1744-1762
The American journal of pathology 2019 Sep;189(9):1744-1762
Nucleus pulposus primary cilia alter their length in response to changes in extracellular osmolarity but do not control TonEBP-mediated osmoregulation.
Choi H, Madhu V, Shapiro IM, Risbud MV
Scientific reports 2019 Oct 29;9(1):15469
Scientific reports 2019 Oct 29;9(1):15469
Patient-derived organoids (PDOs) as a novel in vitro model for neuroblastoma tumours.
Fusco P, Parisatto B, Rampazzo E, Persano L, Frasson C, Di Meglio A, Leslz A, Santoro L, Cafferata B, Zin A, Cimetta E, Basso G, Esposito MR, Tonini GP
BMC cancer 2019 Oct 21;19(1):970
BMC cancer 2019 Oct 21;19(1):970
Modulation of Cathepsin L Expression in the Coronary Arteries of Atherosclerotic Swine.
Gunasekar P, Satish M, Dabestani P, Jiang W, Boosani C, Radwan M, Agrawal D, Asensio J
The Journal of surgical research 2019 Nov;243:460-468
The Journal of surgical research 2019 Nov;243:460-468
Defective fibrin deposition and thrombus stability in Bambi-/- mice are mediated by elevated anticoagulant function.
Crawley JTB, Zalli A, Monkman JH, Petri A, Lane DA, Ahnstrom J, Salles-Crawley II
Journal of thrombosis and haemostasis : JTH 2019 Nov;17(11):1935-1949
Journal of thrombosis and haemostasis : JTH 2019 Nov;17(11):1935-1949
Protein tyrosine phosphatase receptor type R (PTPRR) antagonizes the Wnt signaling pathway in ovarian cancer by dephosphorylating and inactivating β-catenin.
Wang Y, Cao J, Liu W, Zhang J, Wang Z, Zhang Y, Hou L, Chen S, Hao P, Zhang L, Zhuang M, Yu Y, Li D, Fan G
The Journal of biological chemistry 2019 Nov 29;294(48):18306-18323
The Journal of biological chemistry 2019 Nov 29;294(48):18306-18323
The impact of obesity on brain iron levels and α-synuclein expression is regionally dependent.
Han J, Plummer J, Liu L, Byrd A, Aschner M, Erikson KM
Nutritional neuroscience 2019 May;22(5):335-343
Nutritional neuroscience 2019 May;22(5):335-343
Effects of non-euphoric plant cannabinoids on muscle quality and performance of dystrophic mdx mice.
Iannotti FA, Pagano E, Moriello AS, Alvino FG, Sorrentino NC, D'Orsi L, Gazzerro E, Capasso R, De Leonibus E, De Petrocellis L, Di Marzo V
British journal of pharmacology 2019 May;176(10):1568-1584
British journal of pharmacology 2019 May;176(10):1568-1584
Transcriptomics Analysis Reveals New Insights into the Roles of Notch1 Signaling on Macrophage Polarization.
Hans CP, Sharma N, Sen S, Zeng S, Dev R, Jiang Y, Mahajan A, Joshi T
Scientific reports 2019 May 29;9(1):7999
Scientific reports 2019 May 29;9(1):7999
Mesenchymal Stromal Cells Are Required for Regeneration and Homeostatic Maintenance of Skeletal Muscle.
Wosczyna MN, Konishi CT, Perez Carbajal EE, Wang TT, Walsh RA, Gan Q, Wagner MW, Rando TA
Cell reports 2019 May 14;27(7):2029-2035.e5
Cell reports 2019 May 14;27(7):2029-2035.e5
Investigating the effects of Pirfenidone on TGF-β1 stimulated non-SMAD signaling pathways in Dupuytren's disease -derived fibroblasts.
Zhou C, Zeldin Y, Baratz ME, Kathju S, Satish L
BMC musculoskeletal disorders 2019 Mar 30;20(1):135
BMC musculoskeletal disorders 2019 Mar 30;20(1):135
A20 prevents inflammasome-dependent arthritis by inhibiting macrophage necroptosis through its ZnF7 ubiquitin-binding domain.
Polykratis A, Martens A, Eren RO, Shirasaki Y, Yamagishi M, Yamaguchi Y, Uemura S, Miura M, Holzmann B, Kollias G, Armaka M, van Loo G, Pasparakis M
Nature cell biology 2019 Jun;21(6):731-742
Nature cell biology 2019 Jun;21(6):731-742
A novel motif in the proximal C-terminus of Pannexin 1 regulates cell surface localization.
Epp AL, Ebert SN, Sanchez-Arias JC, Wicki-Stordeur LE, Boyce AKJ, Swayne LA
Scientific reports 2019 Jul 5;9(1):9721
Scientific reports 2019 Jul 5;9(1):9721
p53 mutant-type in human prostate cancer cells determines the sensitivity to phenethyl isothiocyanate induced growth inhibition.
Aggarwal M, Saxena R, Asif N, Sinclair E, Tan J, Cruz I, Berry D, Kallakury B, Pham Q, Wang TTY, Chung FL
Journal of experimental & clinical cancer research : CR 2019 Jul 15;38(1):307
Journal of experimental & clinical cancer research : CR 2019 Jul 15;38(1):307
Time series modeling of cell cycle exit identifies Brd4 dependent regulation of cerebellar neurogenesis.
Penas C, Maloof ME, Stathias V, Long J, Tan SK, Mier J, Fang Y, Valdes C, Rodriguez-Blanco J, Chiang CM, Robbins DJ, Liebl DJ, Lee JK, Hatten ME, Clarke J, Ayad NG
Nature communications 2019 Jul 10;10(1):3028
Nature communications 2019 Jul 10;10(1):3028
CCL2 induces resistance to the antiproliferative effect of cabazitaxel in prostate cancer cells.
Natsagdorj A, Izumi K, Hiratsuka K, Machioka K, Iwamoto H, Naito R, Makino T, Kadomoto S, Shigehara K, Kadono Y, Lin WJ, Maolake A, Mizokami A
Cancer science 2019 Jan;110(1):279-288
Cancer science 2019 Jan;110(1):279-288
Extracellular vesicles secreted by hypoxia pre-challenged mesenchymal stem cells promote non-small cell lung cancer cell growth and mobility as well as macrophage M2 polarization via miR-21-5p delivery.
Ren W, Hou J, Yang C, Wang H, Wu S, Wu Y, Zhao X, Lu C
Journal of experimental & clinical cancer research : CR 2019 Feb 8;38(1):62
Journal of experimental & clinical cancer research : CR 2019 Feb 8;38(1):62
C1q/TNF-related protein-9 attenuates atherosclerosis through AMPK-NLRP3 inflammasome singling pathway.
Zhang H, Gong X, Ni S, Wang Y, Zhu L, Ji N
International immunopharmacology 2019 Dec;77:105934
International immunopharmacology 2019 Dec;77:105934
Synthesis and Application of an Activity-Based Peptide-Peptoid Hybrid Probe for the Immunoproteasome.
Zerfas BL, Trader DJ
Current protocols in chemical biology 2019 Dec;11(4):e76
Current protocols in chemical biology 2019 Dec;11(4):e76
Tumor-Associated Macrophages Induce Migration of Renal Cell Carcinoma Cells via Activation of the CCL20-CCR6 Axis.
Kadomoto S, Izumi K, Hiratsuka K, Nakano T, Naito R, Makino T, Iwamoto H, Yaegashi H, Shigehara K, Kadono Y, Nakata H, Saito Y, Nakagawa-Goto K, Mizokami A
Cancers 2019 Dec 30;12(1)
Cancers 2019 Dec 30;12(1)
Transcriptomic profiling of trophoblast fusion using BeWo and JEG-3 cell lines.
Msheik H, El Hayek S, Bari MF, Azar J, Abou-Kheir W, Kobeissy F, Vatish M, Daoud G
Molecular human reproduction 2019 Dec 1;25(12):811-824
Molecular human reproduction 2019 Dec 1;25(12):811-824
Stress-induced phospho-ubiquitin formation causes parkin degradation.
Kovalchuke L, Mosharov EV, Levy OA, Greene LA
Scientific reports 2019 Aug 12;9(1):11682
Scientific reports 2019 Aug 12;9(1):11682
Coffee diterpenes kahweol acetate and cafestol synergistically inhibit the proliferation and migration of prostate cancer cells.
Iwamoto H, Izumi K, Natsagdorj A, Naito R, Makino T, Kadomoto S, Hiratsuka K, Shigehara K, Kadono Y, Narimoto K, Saito Y, Nakagawa-Goto K, Mizokami A
The Prostate 2019 Apr;79(5):468-479
The Prostate 2019 Apr;79(5):468-479
Targeting the phosphorylation site of myristoylated alanine-rich C kinase substrate alleviates symptoms in a murine model of steroid-resistant asthma.
Wang CN, Lin YC, Chang BC, Chen CH, Wu R, Lee CC
British journal of pharmacology 2019 Apr;176(8):1122-1134
British journal of pharmacology 2019 Apr;176(8):1122-1134
Hydrogen Sulfide Abrogates Hemoglobin-Lipid Interaction in Atherosclerotic Lesion.
Potor L, Nagy P, Méhes G, Hendrik Z, Jeney V, Pethő D, Vasas A, Pálinkás Z, Balogh E, Gyetvai Á, Whiteman M, Torregrossa R, Wood ME, Olvasztó S, Nagy P, Balla G, Balla J
Oxidative medicine and cellular longevity 2018;2018:3812568
Oxidative medicine and cellular longevity 2018;2018:3812568
Altered downstream target gene expression of the placental Vitamin D receptor in human idiopathic fetal growth restriction.
Nguyen TPH, Yong HEJ, Chollangi T, Brennecke SP, Fisher SJ, Wallace EM, Ebeling PR, Murthi P
Cell cycle (Georgetown, Tex.) 2018;17(2):182-190
Cell cycle (Georgetown, Tex.) 2018;17(2):182-190
Dynamic MTORC1-TFEB feedback signaling regulates hepatic autophagy, steatosis and liver injury in long-term nutrient oversupply.
Zhang H, Yan S, Khambu B, Ma F, Li Y, Chen X, Martina JA, Puertollano R, Li Y, Chalasani N, Yin XM
Autophagy 2018;14(10):1779-1795
Autophagy 2018;14(10):1779-1795
Loss of Axon Bifurcation in Mesencephalic Trigeminal Neurons Impairs the Maximal Biting Force in Npr2-Deficient Mice.
Ter-Avetisyan G, Dumoulin A, Herrel A, Schmidt H, Strump J, Afzal S, Rathjen FG
Frontiers in cellular neuroscience 2018;12:153
Frontiers in cellular neuroscience 2018;12:153
The Absence of Sensory Axon Bifurcation Affects Nociception and Termination Fields of Afferents in the Spinal Cord.
Tröster P, Haseleu J, Petersen J, Drees O, Schmidtko A, Schwaller F, Lewin GR, Ter-Avetisyan G, Winter Y, Peters S, Feil S, Feil R, Rathjen FG, Schmidt H
Frontiers in molecular neuroscience 2018;11:19
Frontiers in molecular neuroscience 2018;11:19
FANCC localizes with UNC5A at neurite outgrowth and promotes neuritogenesis.
Huang F, Ben Aissa M, Lévesque G, Carreau M
BMC research notes 2018 Sep 12;11(1):662
BMC research notes 2018 Sep 12;11(1):662
Proteomic analysis of the hypothalamus of broiler-type Taiwan country chickens in response to acute heat stress.
Tu WL, Cheng CY, Chen CJ, Chan HL, Wang SH, Tang PC, Chen CF, Chen HH, Lee YP, Chen SE, Huang SY
Animal science journal = Nihon chikusan Gakkaiho 2018 Oct;89(10):1475-1485
Animal science journal = Nihon chikusan Gakkaiho 2018 Oct;89(10):1475-1485
Annotation of differential protein expression in the hypothalami of layer-type Taiwan country chickens in response to acute heat stress.
Tu WL, Cheng CY, Chen CJ, Chan HL, Wang SH, Tang PC, Chen CF, Lee YP, Chen SE, Huang SY
Journal of thermal biology 2018 Oct;77:157-172
Journal of thermal biology 2018 Oct;77:157-172
AngII induces HepG2 cells to activate epithelial-mesenchymal transition.
Qi M, Zhou Y, Liu J, Ou X, Li M, Long X, Ye J, Yu G
Experimental and therapeutic medicine 2018 Oct;16(4):3471-3477
Experimental and therapeutic medicine 2018 Oct;16(4):3471-3477
Tumor necrosis factor-α induces prostate cancer cell migration in lymphatic metastasis through CCR7 upregulation.
Maolake A, Izumi K, Natsagdorj A, Iwamoto H, Kadomoto S, Makino T, Naito R, Shigehara K, Kadono Y, Hiratsuka K, Wufuer G, Nastiuk KL, Mizokami A
Cancer science 2018 May;109(5):1524-1531
Cancer science 2018 May;109(5):1524-1531
C-C motif ligand 5 promotes migration of prostate cancer cells in the prostate cancer bone metastasis microenvironment.
Urata S, Izumi K, Hiratsuka K, Maolake A, Natsagdorj A, Shigehara K, Iwamoto H, Kadomoto S, Makino T, Naito R, Kadono Y, Lin WJ, Wufuer G, Narimoto K, Mizokami A
Cancer science 2018 Mar;109(3):724-731
Cancer science 2018 Mar;109(3):724-731
TRIM11 activates the proteasome and promotes overall protein degradation by regulating USP14.
Chen L, Zhu G, Johns EM, Yang X
Nature communications 2018 Mar 26;9(1):1223
Nature communications 2018 Mar 26;9(1):1223
Downregulation of tight junction protein zonula occludens-2 and urothelium damage in a cyclophosphamide-induced mouse model of cystitis.
Chen YH, Chen CJ, Wang SJ, Lin YN, Chen WC, Tsai MY, Chen HY
Taiwanese journal of obstetrics & gynecology 2018 Jun;57(3):399-406
Taiwanese journal of obstetrics & gynecology 2018 Jun;57(3):399-406
COX-2 expression mediated by calcium-TonEBP signaling axis under hyperosmotic conditions serves osmoprotective function in nucleus pulposus cells.
Choi H, Chaiyamongkol W, Doolittle AC, Johnson ZI, Gogate SS, Schoepflin ZR, Shapiro IM, Risbud MV
The Journal of biological chemistry 2018 Jun 8;293(23):8969-8981
The Journal of biological chemistry 2018 Jun 8;293(23):8969-8981
Histone H3K27 methylation modulates the dynamics of FANCD2 on chromatin to facilitate NHEJ and genome stability.
Zhang Y, Chang JF, Sun J, Chen L, Yang XM, Tang HY, Jing YY, Kang X, He ZM, Wu JY, Wei HM, Wang DL, Xu RG, Zhu RB, Shen Y, Zeng SY, Wang C, Liu KN, Zhang Y, Mao ZY, Jiang CZ, Sun FL
Journal of cell science 2018 Jun 21;131(12)
Journal of cell science 2018 Jun 21;131(12)
Pathogenic mutation in the ALS/FTD gene, CCNF, causes elevated Lys48-linked ubiquitylation and defective autophagy.
Lee A, Rayner SL, Gwee SSL, De Luca A, Shahheydari H, Sundaramoorthy V, Ragagnin A, Morsch M, Radford R, Galper J, Freckleton S, Shi B, Walker AK, Don EK, Cole NJ, Yang S, Williams KL, Yerbury JJ, Blair IP, Atkin JD, Molloy MP, Chung RS
Cellular and molecular life sciences : CMLS 2018 Jan;75(2):335-354
Cellular and molecular life sciences : CMLS 2018 Jan;75(2):335-354
Osteopontin-integrin engagement induces HIF-1α-TCF12-mediated endothelial-mesenchymal transition to exacerbate colorectal cancer.
Fan CS, Chen WS, Chen LL, Chen CC, Hsu YT, Chua KV, Wang HD, Huang TS
Oncotarget 2018 Jan 12;9(4):4998-5015
Oncotarget 2018 Jan 12;9(4):4998-5015
Complement C5a receptors C5L2 and C5aR in renal fibrosis.
Martin IV, Bohner A, Boor P, Shagdarsuren E, Raffetseder U, Lammert F, Floege J, Ostendorf T, Weber SN
American journal of physiology. Renal physiology 2018 Jan 1;314(1):F35-F46
American journal of physiology. Renal physiology 2018 Jan 1;314(1):F35-F46
Laser acupuncture-induced analgesic effect and molecular alterations in an incision pain model: a comparison with electroacupuncture-induced effects.
Zeng YJ, Lin YH, Wang YC, Chang JH, Wu JH, Hsu SF, Tsai SY, Lin CH, Wen YR
Lasers in medical science 2018 Feb;33(2):295-304
Lasers in medical science 2018 Feb;33(2):295-304
The IgCAM CLMP regulates expression of Connexin43 and Connexin45 in intestinal and ureteral smooth muscle contraction in mice.
Langhorst H, Jüttner R, Groneberg D, Mohtashamdolatshahi A, Pelz L, Purfürst B, Schmidt-Ott KM, Friebe A, Rathjen FG
Disease models & mechanisms 2018 Feb 22;11(2)
Disease models & mechanisms 2018 Feb 22;11(2)
Serum retinol-binding protein-induced endothelial inflammation is mediated through the activation of toll-like receptor 4.
Du M, Martin A, Hays F, Johnson J, Farjo RA, Farjo KM
Molecular vision 2017;23:185-197
Molecular vision 2017;23:185-197
Effects of Electroacupuncture on Methamphetamine-Induced Behavioral Changes in Mice.
Ho TJ, Lee CW, Lu ZY, Lane HY, Tsai MH, Ho IK, Huang CL, Chiang YC
Evidence-based complementary and alternative medicine : eCAM 2017;2017:5642708
Evidence-based complementary and alternative medicine : eCAM 2017;2017:5642708
Toxicological effects of NCKU-21, a phenanthrene derivative, on cell growth and migration of A549 and CL1-5 human lung adenocarcinoma cells.
Liao HF, Pan CH, Chou PY, Chen YF, Wu TS, Sheu MJ, Wu CH
PloS one 2017;12(9):e0185021
PloS one 2017;12(9):e0185021
Characterization of a panel of monoclonal antibodies recognizing specific epitopes on GFAP.
Lin NH, Messing A, Perng MD
PloS one 2017;12(7):e0180694
PloS one 2017;12(7):e0180694
Object Phobia and Altered RhoA Signaling in Amygdala of Mice Lacking RICH2.
Sarowar T, Grabrucker S, Boeckers TM, Grabrucker AM
Frontiers in molecular neuroscience 2017;10:180
Frontiers in molecular neuroscience 2017;10:180
Regulation of Focal Adhesion Kinase through a Direct Interaction with an Endogenous Inhibitor.
Zak TJ, Koshman YE, Samarel AM, Robia SL
Biochemistry 2017 Sep 5;56(35):4722-4731
Biochemistry 2017 Sep 5;56(35):4722-4731
The cytoplasmic nuclear receptor RARγ controls RIP1 initiated cell death when cIAP activity is inhibited.
Xu Q, Jitkaew S, Choksi S, Kadigamuwa C, Qu J, Choe M, Jang J, Liu C, Liu ZG
Nature communications 2017 Sep 4;8(1):425
Nature communications 2017 Sep 4;8(1):425
CRISPR-Mediated Base Editing Enables Efficient Disruption of Eukaryotic Genes through Induction of STOP Codons.
Billon P, Bryant EE, Joseph SA, Nambiar TS, Hayward SB, Rothstein R, Ciccia A
Molecular cell 2017 Sep 21;67(6):1068-1079.e4
Molecular cell 2017 Sep 21;67(6):1068-1079.e4
Stabilization of F-actin by tropomyosin isoforms regulates the morphology and mechanical behavior of red blood cells.
Sui Z, Gokhin DS, Nowak RB, Guo X, An X, Fowler VM
Molecular biology of the cell 2017 Sep 15;28(19):2531-2542
Molecular biology of the cell 2017 Sep 15;28(19):2531-2542
Local cellular neighborhood controls proliferation in cell competition.
Bove A, Gradeci D, Fujita Y, Banerjee S, Charras G, Lowe AR
Molecular biology of the cell 2017 Nov 7;28(23):3215-3228
Molecular biology of the cell 2017 Nov 7;28(23):3215-3228
Characterization of epithelial-mesenchymal transition intermediate/hybrid phenotypes associated to resistance to EGFR inhibitors in non-small cell lung cancer cell lines.
Fustaino V, Presutti D, Colombo T, Cardinali B, Papoff G, Brandi R, Bertolazzi P, Felici G, Ruberti G
Oncotarget 2017 Nov 28;8(61):103340-103363
Oncotarget 2017 Nov 28;8(61):103340-103363
Editor's Highlight: Pregnancy Alters Aflatoxin B1 Metabolism and Increases DNA Damage in Mouse Liver.
Sriwattanapong K, Slocum SL, Chawanthayatham S, Fedeles BI, Egner PA, Groopman JD, Satayavivad J, Croy RG, Essigmann JM
Toxicological sciences : an official journal of the Society of Toxicology 2017 Nov 1;160(1):173-179
Toxicological sciences : an official journal of the Society of Toxicology 2017 Nov 1;160(1):173-179
Early cerebellar deficits in mitochondrial biogenesis and respiratory chain complexes in the KIKO mouse model of Friedreich ataxia.
Lin H, Magrane J, Rattelle A, Stepanova A, Galkin A, Clark EM, Dong YN, Halawani SM, Lynch DR
Disease models & mechanisms 2017 Nov 1;10(11):1343-1352
Disease models & mechanisms 2017 Nov 1;10(11):1343-1352
ERK signaling is required for VEGF-A/VEGFR2-induced differentiation of porcine adipose-derived mesenchymal stem cells into endothelial cells.
Almalki SG, Agrawal DK
Stem cell research & therapy 2017 May 12;8(1):113
Stem cell research & therapy 2017 May 12;8(1):113
DNA damage during S-phase mediates the proliferation-quiescence decision in the subsequent G1 via p21 expression.
Barr AR, Cooper S, Heldt FS, Butera F, Stoy H, Mansfeld J, Novák B, Bakal C
Nature communications 2017 Mar 20;8:14728
Nature communications 2017 Mar 20;8:14728
Actin cortex architecture regulates cell surface tension.
Chugh P, Clark AG, Smith MB, Cassani DAD, Dierkes K, Ragab A, Roux PP, Charras G, Salbreux G, Paluch EK
Nature cell biology 2017 Jun;19(6):689-697
Nature cell biology 2017 Jun;19(6):689-697
The mTOR Substrate S6 Kinase 1 (S6K1) Is a Negative Regulator of Axon Regeneration and a Potential Drug Target for Central Nervous System Injury.
Al-Ali H, Ding Y, Slepak T, Wu W, Sun Y, Martinez Y, Xu XM, Lemmon VP, Bixby JL
The Journal of neuroscience : the official journal of the Society for Neuroscience 2017 Jul 26;37(30):7079-7095
The Journal of neuroscience : the official journal of the Society for Neuroscience 2017 Jul 26;37(30):7079-7095
Multiparametric Analysis of Cell Shape Demonstrates that β-PIX Directly Couples YAP Activation to Extracellular Matrix Adhesion.
Sero JE, Bakal C
Cell systems 2017 Jan 25;4(1):84-96.e6
Cell systems 2017 Jan 25;4(1):84-96.e6
HTR-8/SVneo cell line contains a mixed population of cells.
Abou-Kheir W, Barrak J, Hadadeh O, Daoud G
Placenta 2017 Feb;50:1-7
Placenta 2017 Feb;50:1-7
VAPs and ACBD5 tether peroxisomes to the ER for peroxisome maintenance and lipid homeostasis.
Hua R, Cheng D, Coyaud É, Freeman S, Di Pietro E, Wang Y, Vissa A, Yip CM, Fairn GD, Braverman N, Brumell JH, Trimble WS, Raught B, Kim PK
The Journal of cell biology 2017 Feb;216(2):367-377
The Journal of cell biology 2017 Feb;216(2):367-377
Tumor-associated macrophages promote prostate cancer migration through activation of the CCL22-CCR4 axis.
Maolake A, Izumi K, Shigehara K, Natsagdorj A, Iwamoto H, Kadomoto S, Takezawa Y, Machioka K, Narimoto K, Namiki M, Lin WJ, Wufuer G, Mizokami A
Oncotarget 2017 Feb 7;8(6):9739-9751
Oncotarget 2017 Feb 7;8(6):9739-9751
MMP-13 deletion decreases profibrogenic molecules and attenuates N-nitrosodimethylamine-induced liver injury and fibrosis in mice.
George J, Tsutsumi M, Tsuchishima M
Journal of cellular and molecular medicine 2017 Dec;21(12):3821-3835
Journal of cellular and molecular medicine 2017 Dec;21(12):3821-3835
YB-1 orchestrates onset and resolution of renal inflammation via IL10 gene regulation.
Wang J, Djudjaj S, Gibbert L, Lennartz V, Breitkopf DM, Rauen T, Hermert D, Martin IV, Boor P, Braun GS, Floege J, Ostendorf T, Raffetseder U
Journal of cellular and molecular medicine 2017 Dec;21(12):3494-3505
Journal of cellular and molecular medicine 2017 Dec;21(12):3494-3505
Chondromodulin‑I suppresses tumorigenesis of human osteosarcoma cells.
Lin X, Wang L, Wang F
Molecular medicine reports 2017 Dec;16(6):8542-8548
Molecular medicine reports 2017 Dec;16(6):8542-8548
Alternative Polyadenylation of PRELID1 Regulates Mitochondrial ROS Signaling and Cancer Outcomes.
Gillen AE, Brechbuhl HM, Yamamoto TM, Kline E, Pillai MM, Hesselberth JR, Kabos P
Molecular cancer research : MCR 2017 Dec;15(12):1741-1751
Molecular cancer research : MCR 2017 Dec;15(12):1741-1751
Human Astrocytes Transfer Aggregated Alpha-Synuclein via Tunneling Nanotubes.
Rostami J, Holmqvist S, Lindström V, Sigvardson J, Westermark GT, Ingelsson M, Bergström J, Roybon L, Erlandsson A
The Journal of neuroscience : the official journal of the Society for Neuroscience 2017 Dec 6;37(49):11835-11853
The Journal of neuroscience : the official journal of the Society for Neuroscience 2017 Dec 6;37(49):11835-11853
Early VGLUT1-specific parallel fiber synaptic deficits and dysregulated cerebellar circuit in the KIKO mouse model of Friedreich ataxia.
Lin H, Magrane J, Clark EM, Halawani SM, Warren N, Rattelle A, Lynch DR
Disease models & mechanisms 2017 Dec 19;10(12):1529-1538
Disease models & mechanisms 2017 Dec 19;10(12):1529-1538
16-Hydroxycleroda-3, 13-dien-15, 16-olide inhibits the proliferation and induces mitochondrial-dependent apoptosis through Akt, mTOR, and MEK-ERK pathways in human renal carcinoma cells.
Liu C, Lee WC, Huang BM, Chia YC, Chen YC, Chen YC
Phytomedicine : international journal of phytotherapy and phytopharmacology 2017 Dec 1;36:95-107
Phytomedicine : international journal of phytotherapy and phytopharmacology 2017 Dec 1;36:95-107
Keratin 8/18 regulation of insulin receptor signaling and trafficking in hepatocytes through a concerted phosphoinositide-dependent Akt and Rab5 modulation.
Roux A, Loranger A, Lavoie JN, Marceau N
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017 Aug;31(8):3555-3573
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017 Aug;31(8):3555-3573
Timing of Smarcb1 and Nf2 inactivation determines schwannoma versus rhabdoid tumor development.
Vitte J, Gao F, Coppola G, Judkins AR, Giovannini M
Nature communications 2017 Aug 21;8(1):300
Nature communications 2017 Aug 21;8(1):300
A promising protein responsible for overactive bladder in ovariectomized mice.
Chen HY, Chen CJ, Chen WC, Wang SJ, Chen YH
Taiwanese journal of obstetrics & gynecology 2017 Apr;56(2):196-203
Taiwanese journal of obstetrics & gynecology 2017 Apr;56(2):196-203
Vitamin D controls resistance artery function through regulation of perivascular adipose tissue hypoxia and inflammation.
Pelham CJ, Drews EM, Agrawal DK
Journal of molecular and cellular cardiology 2016 Sep;98:1-10
Journal of molecular and cellular cardiology 2016 Sep;98:1-10
PKA inhibits WNT signalling in adrenal cortex zonation and prevents malignant tumour development.
Drelon C, Berthon A, Sahut-Barnola I, Mathieu M, Dumontet T, Rodriguez S, Batisse-Lignier M, Tabbal H, Tauveron I, Lefrançois-Martinez AM, Pointud JC, Gomez-Sanchez CE, Vainio S, Shan J, Sacco S, Schedl A, Stratakis CA, Martinez A, Val P
Nature communications 2016 Sep 14;7:12751
Nature communications 2016 Sep 14;7:12751
Beneficial effects of increased lysozyme levels in Alzheimer's disease modelled in Drosophila melanogaster.
Sandin L, Bergkvist L, Nath S, Kielkopf C, Janefjord C, Helmfors L, Zetterberg H, Blennow K, Li H, Nilsberth C, Garner B, Brorsson AC, Kågedal K
The FEBS journal 2016 Oct;283(19):3508-3522
The FEBS journal 2016 Oct;283(19):3508-3522
Endogenous DNA Damage Leads to p53-Independent Deficits in Replicative Fitness in Fetal Murine Fancd2-/- Hematopoietic Stem and Progenitor Cells.
Yoon YM, Storm KJ, Kamimae-Lanning AN, Goloviznina NA, Kurre P
Stem cell reports 2016 Nov 8;7(5):840-853
Stem cell reports 2016 Nov 8;7(5):840-853
11,12-Epoxyecosatrienoic acids mitigate endothelial dysfunction associated with estrogen loss and aging: Role of membrane depolarization.
Sun C, Simon SI, Foster GA, Radecke CE, Hwang HV, Zhang X, Hammock BD, Chiamvimonvat N, Knowlton AA
Journal of molecular and cellular cardiology 2016 May;94:180-188
Journal of molecular and cellular cardiology 2016 May;94:180-188
PIAS1 Regulates Mutant Huntingtin Accumulation and Huntington's Disease-Associated Phenotypes In Vivo.
Ochaba J, Monteys AM, O'Rourke JG, Reidling JC, Steffan JS, Davidson BL, Thompson LM
Neuron 2016 May 4;90(3):507-20
Neuron 2016 May 4;90(3):507-20
High mobility group box 1-induced epithelial mesenchymal transition in human airway epithelial cells.
Chen YC, Statt S, Wu R, Chang HT, Liao JW, Wang CN, Shyu WC, Lee CC
Scientific reports 2016 Jan 7;6:18815
Scientific reports 2016 Jan 7;6:18815
Patterning of Fibroblast and Matrix Anisotropy within 3D Confinement is Driven by the Cytoskeleton.
Serbo JV, Kuo S, Lewis S, Lehmann M, Li J, Gracias DH, Romer LH
Advanced healthcare materials 2016 Jan 7;5(1):146-58
Advanced healthcare materials 2016 Jan 7;5(1):146-58
Rho-associated kinase (ROCK) function is essential for cell cycle progression, senescence and tumorigenesis.
Kümper S, Mardakheh FK, McCarthy A, Yeo M, Stamp GW, Paul A, Worboys J, Sadok A, Jørgensen C, Guichard S, Marshall CJ
eLife 2016 Jan 14;5:e12994
eLife 2016 Jan 14;5:e12994
Hypomorphic mutations in TRNT1 cause retinitis pigmentosa with erythrocytic microcytosis.
DeLuca AP, Whitmore SS, Barnes J, Sharma TP, Westfall TA, Scott CA, Weed MC, Wiley JS, Wiley LA, Johnston RM, Schnieders MJ, Lentz SR, Tucker BA, Mullins RF, Scheetz TE, Stone EM, Slusarski DC
Human molecular genetics 2016 Jan 1;25(1):44-56
Human molecular genetics 2016 Jan 1;25(1):44-56
Pharmacological induction of ferritin prevents osteoblastic transformation of smooth muscle cells.
Becs G, Zarjou A, Agarwal A, Kovács KÉ, Becs Á, Nyitrai M, Balogh E, Bányai E, Eaton JW, Arosio P, Poli M, Jeney V, Balla J, Balla G
Journal of cellular and molecular medicine 2016 Feb;20(2):217-30
Journal of cellular and molecular medicine 2016 Feb;20(2):217-30
Differentiation of porcine mesenchymal stem cells into epithelial cells as a potential therapeutic application to facilitate epithelial regeneration.
Kokubun K, Pankajakshan D, Kim MJ, Agrawal DK
Journal of tissue engineering and regenerative medicine 2016 Feb;10(2):E73-83
Journal of tissue engineering and regenerative medicine 2016 Feb;10(2):E73-83
Keap1/Nrf2 pathway activation leads to a repressed hepatic gluconeogenic and lipogenic program in mice on a high-fat diet.
Slocum SL, Skoko JJ, Wakabayashi N, Aja S, Yamamoto M, Kensler TW, Chartoumpekis DV
Archives of biochemistry and biophysics 2016 Feb 1;591:57-65
Archives of biochemistry and biophysics 2016 Feb 1;591:57-65
The multi-target effects of CNI-1493: convergence of anti-amylodogenic and anti-inflammatory properties in animal models of Alzheimer's disease.
Sankowski R, Herring A, Keyvani K, Frenzel K, Wu J, Röskam S, Noelker C, Bacher M, Al-Abed Y
Molecular medicine (Cambridge, Mass.) 2016 Dec;22:776-788
Molecular medicine (Cambridge, Mass.) 2016 Dec;22:776-788
Withaferin A induces Nrf2-dependent protection against liver injury: Role of Keap1-independent mechanisms.
Palliyaguru DL, Chartoumpekis DV, Wakabayashi N, Skoko JJ, Yagishita Y, Singh SV, Kensler TW
Free radical biology & medicine 2016 Dec;101:116-128
Free radical biology & medicine 2016 Dec;101:116-128
Differential cytokine sensitivities of STAT5-dependent enhancers rely on Stat5 autoregulation.
Willi M, Yoo KH, Wang C, Trajanoski Z, Hennighausen L
Nucleic acids research 2016 Dec 1;44(21):10277-10291
Nucleic acids research 2016 Dec 1;44(21):10277-10291
Guanylate Binding Protein (GBP) 5 Is an Interferon-Inducible Inhibitor of HIV-1 Infectivity.
Krapp C, Hotter D, Gawanbacht A, McLaren PJ, Kluge SF, Stürzel CM, Mack K, Reith E, Engelhart S, Ciuffi A, Hornung V, Sauter D, Telenti A, Kirchhoff F
Cell host & microbe 2016 Apr 13;19(4):504-14
Cell host & microbe 2016 Apr 13;19(4):504-14
Notch1 Regulates Hippocampal Plasticity Through Interaction with the Reelin Pathway, Glutamatergic Transmission and CREB Signaling.
Brai E, Marathe S, Astori S, Fredj NB, Perry E, Lamy C, Scotti A, Alberi L
Frontiers in cellular neuroscience 2015;9:447
Frontiers in cellular neuroscience 2015;9:447
Status of autophagy, lysosome activity and apoptosis during corpus luteum regression in cattle.
Aboelenain M, Kawahara M, Balboula AZ, Montasser Ael-M, Zaabel SM, Okuda K, Takahashi M
The Journal of reproduction and development 2015;61(3):229-36
The Journal of reproduction and development 2015;61(3):229-36
Atherogenic Cytokines Regulate VEGF-A-Induced Differentiation of Bone Marrow-Derived Mesenchymal Stem Cells into Endothelial Cells.
Ikhapoh IA, Pelham CJ, Agrawal DK
Stem cells international 2015;2015:498328
Stem cells international 2015;2015:498328
Monocytic Tissue Transglutaminase in a Rat Model for Reversible Acute Rejection and Chronic Renal Allograft Injury.
Zakrzewicz A, Atanasova S, Padberg W, Grau V
Mediators of inflammation 2015;2015:429653
Mediators of inflammation 2015;2015:429653
Assembly and interrogation of Alzheimer's disease genetic networks reveal novel regulators of progression.
Aubry S, Shin W, Crary JF, Lefort R, Qureshi YH, Lefebvre C, Califano A, Shelanski ML
PloS one 2015;10(3):e0120352
PloS one 2015;10(3):e0120352
MET Gene Amplification and MET Receptor Activation Are Not Sufficient to Predict Efficacy of Combined MET and EGFR Inhibitors in EGFR TKI-Resistant NSCLC Cells.
Presutti D, Santini S, Cardinali B, Papoff G, Lalli C, Samperna S, Fustaino V, Giannini G, Ruberti G
PloS one 2015;10(11):e0143333
PloS one 2015;10(11):e0143333
Down-regulation of hsa-miR-1264 contributes to DNMT1-mediated silencing of SOCS3.
Boosani CS, Dhar K, Agrawal DK
Molecular biology reports 2015 Sep;42(9):1365-76
Molecular biology reports 2015 Sep;42(9):1365-76
Bub1 autophosphorylation feeds back to regulate kinetochore docking and promote localized substrate phosphorylation.
Asghar A, Lajeunesse A, Dulla K, Combes G, Thebault P, Nigg EA, Elowe S
Nature communications 2015 Sep 24;6:8364
Nature communications 2015 Sep 24;6:8364
Notch signaling in response to excitotoxicity induces neurodegeneration via erroneous cell cycle reentry.
Marathe S, Liu S, Brai E, Kaczarowski M, Alberi L
Cell death and differentiation 2015 Nov;22(11):1775-84
Cell death and differentiation 2015 Nov;22(11):1775-84
Attenuation of acute rat renal allograft rejection by apolipoprotein E-mimetic Peptide.
Zakrzewicz A, Kutlimuratov K, Atanasova S, Zakrzewicz D, Reichert M, Schmitz J, Wilhelm J, Lochnit G, Padberg W, Grau V
Transplantation 2015 May;99(5):925-34
Transplantation 2015 May;99(5):925-34
Post-transcriptional inactivation of matrix metalloproteinase-12 after focal cerebral ischemia attenuates brain damage.
Chelluboina B, Warhekar A, Dillard M, Klopfenstein JD, Pinson DM, Wang DZ, Veeravalli KK
Scientific reports 2015 May 8;5:9504
Scientific reports 2015 May 8;5:9504
A chemical genetics approach for the functional assessment of novel cancer genes.
Zhou Q, Derti A, Ruddy D, Rakiec D, Kao I, Lira M, Gibaja V, Chan H, Yang Y, Min J, Schlabach MR, Stegmeier F
Cancer research 2015 May 15;75(10):1949-58
Cancer research 2015 May 15;75(10):1949-58
Evidence for a functional vasodilatatory role for hydrogen sulphide in the human cutaneous microvasculature.
Kutz JL, Greaney JL, Santhanam L, Alexander LM
The Journal of physiology 2015 May 1;593(9):2121-9
The Journal of physiology 2015 May 1;593(9):2121-9
Prolyl-4-hydroxylase domain protein 2 controls NF-κB/p65 transactivation and enhances the catabolic effects of inflammatory cytokines on cells of the nucleus pulposus.
Li J, Yuan W, Jiang S, Ye W, Yang H, Shapiro IM, Risbud MV
The Journal of biological chemistry 2015 Mar 13;290(11):7195-207
The Journal of biological chemistry 2015 Mar 13;290(11):7195-207
Antiallodynic effects of alpha lipoic acid in an optimized RR-EAE mouse model of MS-neuropathic pain are accompanied by attenuation of upregulated BDNF-TrkB-ERK signaling in the dorsal horn of the spinal cord.
Khan N, Gordon R, Woodruff TM, Smith MT
Pharmacology research & perspectives 2015 Jun;3(3):e00137
Pharmacology research & perspectives 2015 Jun;3(3):e00137
Loss of Androgen-Regulated MicroRNA 1 Activates SRC and Promotes Prostate Cancer Bone Metastasis.
Liu YN, Yin J, Barrett B, Sheppard-Tillman H, Li D, Casey OM, Fang L, Hynes PG, Ameri AH, Kelly K
Molecular and cellular biology 2015 Jun 1;35(11):1940-51
Molecular and cellular biology 2015 Jun 1;35(11):1940-51
Enolase is regulated by Liver X Receptors.
De Boussac H, Maqdasy S, Trousson A, Zelcer N, Volle DH, Lobaccaro JM, Baron S
Steroids 2015 Jul;99(Pt B):266-71
Steroids 2015 Jul;99(Pt B):266-71
Neutralizing anti-interleukin-1β antibodies modulate fetal blood-brain barrier function after ischemia.
Chen X, Sadowska GB, Zhang J, Kim JE, Cummings EE, Bodge CA, Lim YP, Makeyev O, Besio WG, Gaitanis J, Threlkeld SW, Banks WA, Stonestreet BS
Neurobiology of disease 2015 Jan;73:118-29
Neurobiology of disease 2015 Jan;73:118-29
Synergistic effect of angiotensin II on vascular endothelial growth factor-A-mediated differentiation of bone marrow-derived mesenchymal stem cells into endothelial cells.
Ikhapoh IA, Pelham CJ, Agrawal DK
Stem cell research & therapy 2015 Jan 6;6:4
Stem cell research & therapy 2015 Jan 6;6:4
MicroRNA miR145 regulates TGFBR2 expression and matrix synthesis in vascular smooth muscle cells.
Zhao N, Koenig SN, Trask AJ, Lin CH, Hans CP, Garg V, Lilly B
Circulation research 2015 Jan 2;116(1):23-34
Circulation research 2015 Jan 2;116(1):23-34
Xylosyltransferase-1 expression is refractory to inhibition by the inflammatory cytokines tumor necrosis factor α and IL-1β in nucleus pulposus cells: novel regulation by AP-1, Sp1, and Sp3.
Ye W, Zhou J, Markova DZ, Tian Y, Li J, Anderson DG, Shapiro IM, Risbud MV
The American journal of pathology 2015 Feb;185(2):485-95
The American journal of pathology 2015 Feb;185(2):485-95
The Roles of Tight Junctions and Claudin-1 in the Microbubble-Mediated Ultrasound-Induced Enhancement of Drug Concentrations in Rat Prostate.
Shang Y, Dong X, Han G, Li J, Cui D, Liu C, Li L, Yi S
The Journal of membrane biology 2015 Dec;248(6):1167-73
The Journal of membrane biology 2015 Dec;248(6):1167-73
Tropomodulin 1 directly controls thin filament length in both wild-type and tropomodulin 4-deficient skeletal muscle.
Gokhin DS, Ochala J, Domenighetti AA, Fowler VM
Development (Cambridge, England) 2015 Dec 15;142(24):4351-62
Development (Cambridge, England) 2015 Dec 15;142(24):4351-62
Functional constituents of a local serotonergic system, intrinsic to the human coronary artery smooth muscle cells.
Baskar K, Sur S, Selvaraj V, Agrawal DK
Molecular biology reports 2015 Aug;42(8):1295-307
Molecular biology reports 2015 Aug;42(8):1295-307
Systems Analyses Reveal Shared and Diverse Attributes of Oct4 Regulation in Pluripotent Cells.
Ding L, Paszkowski-Rogacz M, Winzi M, Chakraborty D, Theis M, Singh S, Ciotta G, Poser I, Roguev A, Chu WK, Choudhary C, Mann M, Stewart AF, Krogan N, Buchholz F
Cell systems 2015 Aug 26;1(2):141-51
Cell systems 2015 Aug 26;1(2):141-51
Force transmission during adhesion-independent migration.
Bergert M, Erzberger A, Desai RA, Aspalter IM, Oates AC, Charras G, Salbreux G, Paluch EK
Nature cell biology 2015 Apr;17(4):524-9
Nature cell biology 2015 Apr;17(4):524-9
Effect of obesity and exercise on the expression of the novel myokines, Myonectin and Fibronectin type III domain containing 5.
Peterson JM, Mart R, Bond CE
PeerJ 2014;2:e605
PeerJ 2014;2:e605
Selenite cataracts: activation of endoplasmic reticulum stress and loss of Nrf2/Keap1-dependent stress protection.
Palsamy P, Bidasee KR, Shinohara T
Biochimica et biophysica acta 2014 Sep;1842(9):1794-805
Biochimica et biophysica acta 2014 Sep;1842(9):1794-805
Tumor necrosis factor-α- and interleukin-1β-dependent matrix metalloproteinase-3 expression in nucleus pulposus cells requires cooperative signaling via syndecan 4 and mitogen-activated protein kinase-NF-κB axis: implications in inflammatory disc disease.
Wang X, Wang H, Yang H, Li J, Cai Q, Shapiro IM, Risbud MV
The American journal of pathology 2014 Sep;184(9):2560-72
The American journal of pathology 2014 Sep;184(9):2560-72
HEK-293 cells expressing the cystic fibrosis transmembrane conductance regulator (CFTR): a model for studying regulation of Cl- transport.
Domingue JC, Ao M, Sarathy J, George A, Alrefai WA, Nelson DJ, Rao MC
Physiological reports 2014 Sep 1;2(9)
Physiological reports 2014 Sep 1;2(9)
The PSD protein ProSAP2/Shank3 displays synapto-nuclear shuttling which is deregulated in a schizophrenia-associated mutation.
Grabrucker S, Proepper C, Mangus K, Eckert M, Chhabra R, Schmeisser MJ, Boeckers TM, Grabrucker AM
Experimental neurology 2014 Mar;253:126-37
Experimental neurology 2014 Mar;253:126-37
Calpain-mediated proteolysis of tropomodulin isoforms leads to thin filament elongation in dystrophic skeletal muscle.
Gokhin DS, Tierney MT, Sui Z, Sacco A, Fowler VM
Molecular biology of the cell 2014 Mar;25(6):852-65
Molecular biology of the cell 2014 Mar;25(6):852-65
Cyclin e1 regulates Kv2.1 channel phosphorylation and localization in neuronal ischemia.
Shah NH, Schulien AJ, Clemens K, Aizenman TD, Hageman TM, Wills ZP, Aizenman E
The Journal of neuroscience : the official journal of the Society for Neuroscience 2014 Mar 19;34(12):4326-31
The Journal of neuroscience : the official journal of the Society for Neuroscience 2014 Mar 19;34(12):4326-31
Genetic or pharmacologic activation of Nrf2 signaling fails to protect against aflatoxin genotoxicity in hypersensitive GSTA3 knockout mice.
Kensler KH, Slocum SL, Chartoumpekis DV, Dolan PM, Johnson NM, Ilic Z, Crawford DR, Sell S, Groopman JD, Kensler TW, Egner PA
Toxicological sciences : an official journal of the Society of Toxicology 2014 Jun;139(2):293-300
Toxicological sciences : an official journal of the Society of Toxicology 2014 Jun;139(2):293-300
Methylglyoxal induces endoplasmic reticulum stress and DNA demethylation in the Keap1 promoter of human lens epithelial cells and age-related cataracts.
Palsamy P, Bidasee KR, Ayaki M, Augusteyn RC, Chan JY, Shinohara T
Free radical biology & medicine 2014 Jul;72:134-48
Free radical biology & medicine 2014 Jul;72:134-48
Pen-2 is essential for γ-secretase complex stability and trafficking but partially dispensable for endoproteolysis.
Holmes O, Paturi S, Selkoe DJ, Wolfe MS
Biochemistry 2014 Jul 15;53(27):4393-406
Biochemistry 2014 Jul 15;53(27):4393-406
Changes in protein expression in testes of L2 strain Taiwan country chickens in response to acute heat stress.
Wang SH, Cheng CY, Chen CJ, Chen HH, Tang PC, Chen CF, Lee YP, Huang SY
Theriogenology 2014 Jul 1;82(1):80-94
Theriogenology 2014 Jul 1;82(1):80-94
TGF-β promotes glioma cell growth via activating Nodal expression through Smad and ERK1/2 pathways.
Sun J, Liu SZ, Lin Y, Cao XP, Liu JM
Biochemical and biophysical research communications 2014 Jan 17;443(3):1066-72
Biochemical and biophysical research communications 2014 Jan 17;443(3):1066-72
Temporal regulation of apoptotic and anti-apoptotic molecules after middle cerebral artery occlusion followed by reperfusion.
Chelluboina B, Klopfenstein JD, Gujrati M, Rao JS, Veeravalli KK
Molecular neurobiology 2014 Feb;49(1):50-65
Molecular neurobiology 2014 Feb;49(1):50-65
Tumor microenvironment-associated modifications of alternative splicing.
Brosseau JP, Lucier JF, Nwilati H, Thibault P, Garneau D, Gendron D, Durand M, Couture S, Lapointe E, Prinos P, Klinck R, Perreault JP, Chabot B, Abou-Elela S
RNA (New York, N.Y.) 2014 Feb;20(2):189-201
RNA (New York, N.Y.) 2014 Feb;20(2):189-201
Alanine repeats influence protein localization in splicing speckles and paraspeckles.
Chang SH, Chang WL, Lu CC, Tarn WY
Nucleic acids research 2014 Dec 16;42(22):13788-98
Nucleic acids research 2014 Dec 16;42(22):13788-98
Arsenic inhibits hedgehog signaling during P19 cell differentiation.
Liu JT, Bain LJ
Toxicology and applied pharmacology 2014 Dec 15;281(3):243-53
Toxicology and applied pharmacology 2014 Dec 15;281(3):243-53
Rare GATA5 sequence variants identified in individuals with bicuspid aortic valve.
Bonachea EM, Chang SW, Zender G, LaHaye S, Fitzgerald-Butt S, McBride KL, Garg V
Pediatric research 2014 Aug;76(2):211-6
Pediatric research 2014 Aug;76(2):211-6
Stem cell treatment after cerebral ischemia regulates the gene expression of apoptotic molecules.
Chelluboina B, Klopfenstein JD, Pinson DM, Wang DZ, Veeravalli KK
Neurochemical research 2014 Aug;39(8):1511-21
Neurochemical research 2014 Aug;39(8):1511-21
Syntaxin-binding domain of Kv2.1 is essential for the expression of apoptotic K+ currents.
McCord MC, Kullmann PH, He K, Hartnett KA, Horn JP, Lotan I, Aizenman E
The Journal of physiology 2014 Aug 15;592(16):3511-21
The Journal of physiology 2014 Aug 15;592(16):3511-21
Calcineurin-mediated YB-1 dephosphorylation regulates CCL5 expression during monocyte differentiation.
Alidousty C, Rauen T, Hanssen L, Wang Q, Alampour-Rajabi S, Mertens PR, Bernhagen J, Floege J, Ostendorf T, Raffetseder U
The Journal of biological chemistry 2014 Aug 1;289(31):21401-12
The Journal of biological chemistry 2014 Aug 1;289(31):21401-12
Exercise, vascular stiffness, and tissue transglutaminase.
Steppan J, Sikka G, Jandu S, Barodka V, Halushka MK, Flavahan NA, Belkin AM, Nyhan D, Butlin M, Avolio A, Berkowitz DE, Santhanam L
Journal of the American Heart Association 2014 Apr 10;3(2):e000599
Journal of the American Heart Association 2014 Apr 10;3(2):e000599
Monoubiquitination of ancient ubiquitous protein 1 promotes lipid droplet clustering.
Lohmann D, Spandl J, Stevanovic A, Schoene M, Philippou-Massier J, Thiele C
PloS one 2013;8(9):e72453
PloS one 2013;8(9):e72453
Structural analysis of microRNA-target interaction by sequential seed mutagenesis and stem-loop 3' RACE.
Bohmer M, Sharbati J, Zur Bruegge J, Einspanier R, Sharbati S
PloS one 2013;8(11):e81427
PloS one 2013;8(11):e81427
Atherogenesis may involve the prooxidant and proinflammatory effects of ferryl hemoglobin.
Potor L, Bányai E, Becs G, Soares MP, Balla G, Balla J, Jeney V
Oxidative medicine and cellular longevity 2013;2013:676425
Oxidative medicine and cellular longevity 2013;2013:676425
Shared and cell type-specific mitochondrial defects and metabolic adaptations in primary cells from PINK1-deficient mice.
Akundi RS, Zhi L, Sullivan PG, Büeler H
Neuro-degenerative diseases 2013;12(3):136-49
Neuro-degenerative diseases 2013;12(3):136-49
Serum from minimal change patients in relapse increases CD80 expression in cultured podocytes.
Ishimoto T, Cara-Fuentes G, Wang H, Shimada M, Wasserfall CH, Winter WE, Rivard CJ, Araya CE, Saleem MA, Mathieson PW, Johnson RJ, Garin EH
Pediatric nephrology (Berlin, Germany) 2013 Sep;28(9):1803-12
Pediatric nephrology (Berlin, Germany) 2013 Sep;28(9):1803-12
Increased tissue transglutaminase activity contributes to central vascular stiffness in eNOS knockout mice.
Jung SM, Jandu S, Steppan J, Belkin A, An SS, Pak A, Choi EY, Nyhan D, Butlin M, Viegas K, Avolio A, Berkowitz DE, Santhanam L
American journal of physiology. Heart and circulatory physiology 2013 Sep 15;305(6):H803-10
American journal of physiology. Heart and circulatory physiology 2013 Sep 15;305(6):H803-10
YB-1 is an early and central mediator of bacterial and sterile inflammation in vivo.
Hanssen L, Alidousty C, Djudjaj S, Frye BC, Rauen T, Boor P, Mertens PR, van Roeyen CR, Tacke F, Heymann F, Tittel AP, Koch A, Floege J, Ostendorf T, Raffetseder U
Journal of immunology (Baltimore, Md. : 1950) 2013 Sep 1;191(5):2604-13
Journal of immunology (Baltimore, Md. : 1950) 2013 Sep 1;191(5):2604-13
The performance of an orthosilicic acid-releasing silica gel fiber fleece in wound healing.
Grotheer V, Goergens M, Fuchs PC, Dunda S, Pallua N, Windolf J, Suschek CV
Biomaterials 2013 Oct;34(30):7314-27
Biomaterials 2013 Oct;34(30):7314-27
Focal adhesion kinase mediates β-catenin signaling in periodontal ligament cells.
Premaraj S, Souza I, Premaraj T
Biochemical and biophysical research communications 2013 Oct 4;439(4):487-92
Biochemical and biophysical research communications 2013 Oct 4;439(4):487-92
Zyxin cooperates with PTOV1 to confer retinoic acid resistance by repressing RAR activity.
Youn H, Kim EJ, Um SJ
Cancer letters 2013 May 1;331(2):192-9
Cancer letters 2013 May 1;331(2):192-9
Tumor necrosis factor α- and interleukin-1β-dependent induction of CCL3 expression by nucleus pulposus cells promotes macrophage migration through CCR1.
Wang J, Tian Y, Phillips KL, Chiverton N, Haddock G, Bunning RA, Cross AK, Shapiro IM, Le Maitre CL, Risbud MV
Arthritis and rheumatism 2013 Mar;65(3):832-42
Arthritis and rheumatism 2013 Mar;65(3):832-42
Expression and biologic significance of adiponectin receptors in papillary thyroid carcinoma.
Cheng SP, Liu CL, Hsu YC, Chang YC, Huang SY, Lee JJ
Cell biochemistry and biophysics 2013 Mar;65(2):203-10
Cell biochemistry and biophysics 2013 Mar;65(2):203-10
Knockdown of GPC3 inhibits the proliferation of Huh7 hepatocellular carcinoma cells through down-regulation of YAP.
Miao HL, Pan ZJ, Lei CJ, Wen JY, Li MY, Liu ZK, Qiu ZD, Lin MZ, Chen NP, Chen M
Journal of cellular biochemistry 2013 Mar;114(3):625-31
Journal of cellular biochemistry 2013 Mar;114(3):625-31
SOCS3 promotor hypermethylation and STAT3-NF-κB interaction downregulate SOCS3 expression in human coronary artery smooth muscle cells.
Dhar K, Rakesh K, Pankajakshan D, Agrawal DK
American journal of physiology. Heart and circulatory physiology 2013 Mar 15;304(6):H776-85
American journal of physiology. Heart and circulatory physiology 2013 Mar 15;304(6):H776-85
Inflammatory cytokines associated with degenerative disc disease control aggrecanase-1 (ADAMTS-4) expression in nucleus pulposus cells through MAPK and NF-κB.
Tian Y, Yuan W, Fujita N, Wang J, Wang H, Shapiro IM, Risbud MV
The American journal of pathology 2013 Jun;182(6):2310-21
The American journal of pathology 2013 Jun;182(6):2310-21
Inflammatory cytokines induce NOTCH signaling in nucleus pulposus cells: implications in intervertebral disc degeneration.
Wang H, Tian Y, Wang J, Phillips KL, Binch AL, Dunn S, Cross A, Chiverton N, Zheng Z, Shapiro IM, Le Maitre CL, Risbud MV
The Journal of biological chemistry 2013 Jun 7;288(23):16761-74
The Journal of biological chemistry 2013 Jun 7;288(23):16761-74
Endothelial nitric oxide signaling regulates Notch1 in aortic valve disease.
Bosse K, Hans CP, Zhao N, Koenig SN, Huang N, Guggilam A, LaHaye S, Tao G, Lucchesi PA, Lincoln J, Lilly B, Garg V
Journal of molecular and cellular cardiology 2013 Jul;60:27-35
Journal of molecular and cellular cardiology 2013 Jul;60:27-35
O-GlcNAcylation of αB-crystallin regulates its stress-induced translocation and cytoprotection.
Krishnamoorthy V, Donofrio AJ, Martin JL
Molecular and cellular biochemistry 2013 Jul;379(1-2):59-68
Molecular and cellular biochemistry 2013 Jul;379(1-2):59-68
Factors controlling nascent high-density lipoprotein particle heterogeneity: ATP-binding cassette transporter A1 activity and cell lipid and apolipoprotein AI availability.
Lyssenko NN, Nickel M, Tang C, Phillips MC
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2013 Jul;27(7):2880-92
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2013 Jul;27(7):2880-92
Reciprocal regulation of p53 and malic enzymes modulates metabolism and senescence.
Jiang P, Du W, Mancuso A, Wellen KE, Yang X
Nature 2013 Jan 31;493(7434):689-93
Nature 2013 Jan 31;493(7434):689-93
A novel cell-penetrating peptide TAT-A1 delivers siRNA into tumor cells selectively.
Fang B, Jiang L, Zhang M, Ren FZ
Biochimie 2013 Feb;95(2):251-7
Biochimie 2013 Feb;95(2):251-7
The six amino acid antimicrobial peptide bLFcin6 penetrates cells and delivers siRNA.
Fang B, Guo HY, Zhang M, Jiang L, Ren FZ
The FEBS journal 2013 Feb;280(4):1007-17
The FEBS journal 2013 Feb;280(4):1007-17
A genome-wide RNAi screen identifies proteins modulating aberrant FLT3-ITD signaling.
Caldarelli A, Müller JP, Paskowski-Rogacz M, Herrmann K, Bauer R, Koch S, Heninger AK, Krastev D, Ding L, Kasper S, Fischer T, Brodhun M, Böhmer FD, Buchholz F
Leukemia 2013 Dec;27(12):2301-10
Leukemia 2013 Dec;27(12):2301-10
Alternative polyadenylation and miR-34 family members regulate tau expression.
Dickson JR, Kruse C, Montagna DR, Finsen B, Wolfe MS
Journal of neurochemistry 2013 Dec;127(6):739-49
Journal of neurochemistry 2013 Dec;127(6):739-49
The terminal pathway of the complement system is activated in focal penetrating but not in mild diffuse traumatic brain injury.
Rostami E, Davidsson J, Gyorgy A, Agoston DV, Risling M, Bellander BM
Journal of neurotrauma 2013 Dec 1;30(23):1954-65
Journal of neurotrauma 2013 Dec 1;30(23):1954-65
GogB is an anti-inflammatory effector that limits tissue damage during Salmonella infection through interaction with human FBXO22 and Skp1.
Pilar AV, Reid-Yu SA, Cooper CA, Mulder DT, Coombes BK
PLoS pathogens 2012;8(6):e1002773
PLoS pathogens 2012;8(6):e1002773
Tmod1 and CP49 synergize to control the fiber cell geometry, transparency, and mechanical stiffness of the mouse lens.
Gokhin DS, Nowak RB, Kim NE, Arnett EE, Chen AC, Sah RL, Clark JI, Fowler VM
PloS one 2012;7(11):e48734
PloS one 2012;7(11):e48734
HIF-1α contributes to hypoxia-induced invasion and metastasis of esophageal carcinoma via inhibiting E-cadherin and promoting MMP-2 expression.
Jing SW, Wang YD, Kuroda M, Su JW, Sun GG, Liu Q, Cheng YJ, Yang CR
Acta medica Okayama 2012;66(5):399-407
Acta medica Okayama 2012;66(5):399-407
Contractile Activity Regulates Inducible Nitric Oxide Synthase Expression and NO(i) Production in Cardiomyocytes via a FAK-Dependent Signaling Pathway.
Chu M, Koshman Y, Iyengar R, Kim T, Russell B, Samarel AM
Journal of signal transduction 2012;2012:473410
Journal of signal transduction 2012;2012:473410
Arsenic exposure inhibits myogenesis and neurogenesis in P19 stem cells through repression of the β-catenin signaling pathway.
Hong GM, Bain LJ
Toxicological sciences : an official journal of the Society of Toxicology 2012 Sep;129(1):146-56
Toxicological sciences : an official journal of the Society of Toxicology 2012 Sep;129(1):146-56
Age-related cataracts: homocysteine coupled endoplasmic reticulum stress and suppression of Nrf2-dependent antioxidant protection.
Elanchezhian R, Palsamy P, Madson CJ, Lynch DW, Shinohara T
Chemico-biological interactions 2012 Oct 25;200(1):1-10
Chemico-biological interactions 2012 Oct 25;200(1):1-10
Notch-3 receptor activation drives inflammation and fibrosis following tubulointerstitial kidney injury.
Djudjaj S, Chatziantoniou C, Raffetseder U, Guerrot D, Dussaule JC, Boor P, Kerroch M, Hanssen L, Brandt S, Dittrich A, Ostendorf T, Floege J, Zhu C, Lindenmeyer M, Cohen CD, Mertens PR
The Journal of pathology 2012 Nov;228(3):286-99
The Journal of pathology 2012 Nov;228(3):286-99
Genetic deletion of RALA and RALB small GTPases reveals redundant functions in development and tumorigenesis.
Peschard P, McCarthy A, Leblanc-Dominguez V, Yeo M, Guichard S, Stamp G, Marshall CJ
Current biology : CB 2012 Nov 6;22(21):2063-8
Current biology : CB 2012 Nov 6;22(21):2063-8
Platelet lysate suppresses the expression of lipocalin-type prostaglandin D2 synthase that positively controls adipogenic differentiation of human mesenchymal stromal cells.
Lange C, Brunswig-Spickenheier B, Eissing L, Scheja L
Experimental cell research 2012 Nov 1;318(18):2284-96
Experimental cell research 2012 Nov 1;318(18):2284-96
Histone deacetylase inhibition facilitates GM-CSF-mediated expansion of myeloid-derived suppressor cells in vitro and in vivo.
Rosborough BR, Castellaneta A, Natarajan S, Thomson AW, Turnquist HR
Journal of leukocyte biology 2012 May;91(5):701-9
Journal of leukocyte biology 2012 May;91(5):701-9
Differential response of arterial and venous endothelial cells to extracellular matrix is modulated by oxygen.
Lassance L, Miedl H, Konya V, Heinemann A, Ebner B, Hackl H, Desoye G, Hiden U
Histochemistry and cell biology 2012 May;137(5):641-55
Histochemistry and cell biology 2012 May;137(5):641-55
A high-throughput FRET-based assay for determination of Atg4 activity.
Li M, Chen X, Ye QZ, Vogt A, Yin XM
Autophagy 2012 Mar;8(3):401-12
Autophagy 2012 Mar;8(3):401-12
IL-27 production and STAT3-dependent upregulation of B7-H1 mediate immune regulatory functions of liver plasmacytoid dendritic cells.
Matta BM, Raimondi G, Rosborough BR, Sumpter TL, Thomson AW
Journal of immunology (Baltimore, Md. : 1950) 2012 Jun 1;188(11):5227-37
Journal of immunology (Baltimore, Md. : 1950) 2012 Jun 1;188(11):5227-37
PINK1 enhances insulin-like growth factor-1-dependent Akt signaling and protection against apoptosis.
Akundi RS, Zhi L, Büeler H
Neurobiology of disease 2012 Jan;45(1):469-78
Neurobiology of disease 2012 Jan;45(1):469-78
Integrin α9β1-mediated cell migration in glioblastoma via SSAT and Kir4.2 potassium channel pathway.
Veeravalli KK, Ponnala S, Chetty C, Tsung AJ, Gujrati M, Rao JS
Cellular signalling 2012 Jan;24(1):272-81
Cellular signalling 2012 Jan;24(1):272-81
Reduced expression of UGT1A1 in intestines of humanized UGT1 mice via inactivation of NF-κB leads to hyperbilirubinemia.
Fujiwara R, Chen S, Karin M, Tukey RH
Gastroenterology 2012 Jan;142(1):109-118.e2
Gastroenterology 2012 Jan;142(1):109-118.e2
A high calcium diet containing nonfat dry milk reduces weight gain and associated adipose tissue inflammation in diet-induced obese mice when compared to high calcium alone.
Thomas AP, Dunn TN, Drayton JB, Oort PJ, Adams SH
Nutrition & metabolism 2012 Jan 23;9(1):3
Nutrition & metabolism 2012 Jan 23;9(1):3
Identification of potential markers related to neoadjuvant chemotherapy sensitivity of breast cancer by SELDI-TOF MS.
Zhang K, Yuan K, Wu H, Li Q, Wang Y, Chen S, Zhang L, Gu H, Fu R
Applied biochemistry and biotechnology 2012 Feb;166(3):753-63
Applied biochemistry and biotechnology 2012 Feb;166(3):753-63
Thin-filament length correlates with fiber type in human skeletal muscle.
Gokhin DS, Kim NE, Lewis SA, Hoenecke HR, D'Lima DD, Fowler VM
American journal of physiology. Cell physiology 2012 Feb 1;302(3):C555-65
American journal of physiology. Cell physiology 2012 Feb 1;302(3):C555-65
Proliferation and differentiation of osteoblastic cells on silicon-doped TiO(2) film deposited by cathodic arc.
Wang B, Sun J, Qian S, Liu X, Zhang S, Liu F, Dong S, Zha G
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2012 Dec;66(8):633-41
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2012 Dec;66(8):633-41
Retinol-binding protein 4 induces inflammation in human endothelial cells by an NADPH oxidase- and nuclear factor kappa B-dependent and retinol-independent mechanism.
Farjo KM, Farjo RA, Halsey S, Moiseyev G, Ma JX
Molecular and cellular biology 2012 Dec;32(24):5103-15
Molecular and cellular biology 2012 Dec;32(24):5103-15
Chronic central administration of valproic acid: Increased pro-survival phospho-proteins and growth cone associated proteins with no behavioral pathology.
Bates RC, Stith BJ, Stevens KE
Pharmacology, biochemistry, and behavior 2012 Dec;103(2):237-44
Pharmacology, biochemistry, and behavior 2012 Dec;103(2):237-44
CDK5 regulatory subunit-associated protein 1-like 1 (CDKAL1) is a tail-anchored protein in the endoplasmic reticulum (ER) of insulinoma cells.
Brambillasca S, Altkrueger A, Colombo SF, Friederich A, Eickelmann P, Mark M, Borgese N, Solimena M
The Journal of biological chemistry 2012 Dec 7;287(50):41808-19
The Journal of biological chemistry 2012 Dec 7;287(50):41808-19
Ischemia-reperfusion impairs blood-brain barrier function and alters tight junction protein expression in the ovine fetus.
Chen X, Threlkeld SW, Cummings EE, Juan I, Makeyev O, Besio WG, Gaitanis J, Banks WA, Sadowska GB, Stonestreet BS
Neuroscience 2012 Dec 13;226:89-100
Neuroscience 2012 Dec 13;226:89-100
The Ca(v)3.1 T-type calcium channel is required for neointimal formation in response to vascular injury in mice.
Tzeng BH, Chen YH, Huang CH, Lin SS, Lee KR, Chen CC
Cardiovascular research 2012 Dec 1;96(3):533-42
Cardiovascular research 2012 Dec 1;96(3):533-42
Down-regulation of calcium/calmodulin-dependent protein kinase kinase 2 by androgen deprivation induces castration-resistant prostate cancer.
Shima T, Mizokami A, Miyagi T, Kawai K, Izumi K, Kumaki M, Ofude M, Zhang J, Keller ET, Namiki M
The Prostate 2012 Dec 1;72(16):1789-801
The Prostate 2012 Dec 1;72(16):1789-801
Reovirus exerts potent oncolytic effects in head and neck cancer cell lines that are independent of signalling in the EGFR pathway.
Twigger K, Roulstone V, Kyula J, Karapanagiotou EM, Syrigos KN, Morgan R, White C, Bhide S, Nuovo G, Coffey M, Thompson B, Jebar A, Errington F, Melcher AA, Vile RG, Pandha HS, Harrington KJ
BMC cancer 2012 Aug 24;12:368
BMC cancer 2012 Aug 24;12:368
Cigarette smoke induces MUC5AC protein expression through the activation of Sp1.
Di YP, Zhao J, Harper R
The Journal of biological chemistry 2012 Aug 10;287(33):27948-58
The Journal of biological chemistry 2012 Aug 10;287(33):27948-58
Altered mTOR signaling and enhanced CYFIP2 expression levels in subjects with fragile X syndrome.
Hoeffer CA, Sanchez E, Hagerman RJ, Mu Y, Nguyen DV, Wong H, Whelan AM, Zukin RS, Klann E, Tassone F
Genes, brain, and behavior 2012 Apr;11(3):332-41
Genes, brain, and behavior 2012 Apr;11(3):332-41
Low glucose under hypoxic conditions induces unfolded protein response and produces reactive oxygen species in lens epithelial cells.
Elanchezhian R, Palsamy P, Madson CJ, Mulhern ML, Lynch DW, Troia AM, Usukura J, Shinohara T
Cell death & disease 2012 Apr 19;3:e301
Cell death & disease 2012 Apr 19;3:e301
The metastasis gene NEDD9 product acts through integrin β3 and Src to promote mesenchymal motility and inhibit amoeboid motility.
Ahn J, Sanz-Moreno V, Marshall CJ
Journal of cell science 2012 Apr 1;125(Pt 7):1814-26
Journal of cell science 2012 Apr 1;125(Pt 7):1814-26
Cell-cell contact preserves cell viability via plakoglobin.
Wei Q, Hariharan V, Huang H
PloS one 2011;6(10):e27064
PloS one 2011;6(10):e27064
Identification of hnRNPH1, NF45, and C14orf166 as novel host interacting partners of the mature hepatitis C virus core protein.
Lee JW, Liao PC, Young KC, Chang CL, Chen SS, Chang TT, Lai MD, Wang SW
Journal of proteome research 2011 Oct 7;10(10):4522-34
Journal of proteome research 2011 Oct 7;10(10):4522-34
p53 target Siva regulates apoptosis in ischemic kidneys.
Singaravelu K, Padanilam BJ
American journal of physiology. Renal physiology 2011 May;300(5):F1130-41
American journal of physiology. Renal physiology 2011 May;300(5):F1130-41
Human neuroglobin functions as a redox-regulated nitrite reductase.
Tiso M, Tejero J, Basu S, Azarov I, Wang X, Simplaceanu V, Frizzell S, Jayaraman T, Geary L, Shapiro C, Ho C, Shiva S, Kim-Shapiro DB, Gladwin MT
The Journal of biological chemistry 2011 May 20;286(20):18277-89
The Journal of biological chemistry 2011 May 20;286(20):18277-89
RAD21 cooperates with pluripotency transcription factors in the maintenance of embryonic stem cell identity.
Nitzsche A, Paszkowski-Rogacz M, Matarese F, Janssen-Megens EM, Hubner NC, Schulz H, de Vries I, Ding L, Huebner N, Mann M, Stunnenberg HG, Buchholz F
PloS one 2011 May 12;6(5):e19470
PloS one 2011 May 12;6(5):e19470
Prostate epithelial Pten/TP53 loss leads to transformation of multipotential progenitors and epithelial to mesenchymal transition.
Martin P, Liu YN, Pierce R, Abou-Kheir W, Casey O, Seng V, Camacho D, Simpson RM, Kelly K
The American journal of pathology 2011 Jul;179(1):422-35
The American journal of pathology 2011 Jul;179(1):422-35
Elevated levels of uterine anti-apoptotic signaling may activate NFKB and potentially confer resistance to caspase 3-mediated apoptotic cell death during pregnancy in mice.
Jeyasuria P, Subedi K, Suresh A, Condon JC
Biology of reproduction 2011 Aug;85(2):417-24
Biology of reproduction 2011 Aug;85(2):417-24
Latent membrane protein 1 of Epstein-Barr virus regulates death-associated protein kinase 1 in lymphoblastoid cell line.
Lee CW, Leu SJ, Tzeng RY, Wang SF, Tsai SC, Sun KH, Chen RH, Huang JC
Virology 2011 Apr 25;413(1):19-25
Virology 2011 Apr 25;413(1):19-25
Phosphodiesterase 10A upregulation contributes to pulmonary vascular remodeling.
Tian X, Vroom C, Ghofrani HA, Weissmann N, Bieniek E, Grimminger F, Seeger W, Schermuly RT, Pullamsetti SS
PloS one 2011 Apr 11;6(4):e18136
PloS one 2011 Apr 11;6(4):e18136
The pattern of expression of guanine nucleotide-binding protein beta3 in the retina is conserved across vertebrate species.
Ritchey ER, Bongini RE, Code KA, Zelinka C, Petersen-Jones S, Fischer AJ
Neuroscience 2010 Sep 1;169(3):1376-91
Neuroscience 2010 Sep 1;169(3):1376-91
MicroRNA-200 family members differentially regulate morphological plasticity and mode of melanoma cell invasion.
Elson-Schwab I, Lorentzen A, Marshall CJ
PloS one 2010 Oct 4;5(10)
PloS one 2010 Oct 4;5(10)
Iris pigment epithelial cells express a functional lipopolysaccharide receptor complex.
Chui JJ, Li MW, Di Girolamo N, Chang JH, McCluskey PJ, Wakefield D
Investigative ophthalmology & visual science 2010 May;51(5):2558-67
Investigative ophthalmology & visual science 2010 May;51(5):2558-67
NHE3 function and phosphorylation are regulated by a calyculin A-sensitive phosphatase.
Dynia DW, Steinmetz AG, Kocinsky HS
American journal of physiology. Renal physiology 2010 Mar;298(3):F745-53
American journal of physiology. Renal physiology 2010 Mar;298(3):F745-53
Role of androgens and the androgen receptor in epithelial-mesenchymal transition and invasion of prostate cancer cells.
Zhu ML, Kyprianou N
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010 Mar;24(3):769-77
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010 Mar;24(3):769-77
Regulation of vascular endothelial growth factor-induced endothelial cell migration by LIM kinase 1-mediated phosphorylation of annexin 1.
Côté MC, Lavoie JR, Houle F, Poirier A, Rousseau S, Huot J
The Journal of biological chemistry 2010 Mar 12;285(11):8013-21
The Journal of biological chemistry 2010 Mar 12;285(11):8013-21
Role of mouse hepatitis virus (MHV) receptor murine CEACAM1 in the resistance of mice to MHV infection: studies of mice with chimeric mCEACAM1a and mCEACAM1b.
Hirai A, Ohtsuka N, Ikeda T, Taniguchi R, Blau D, Nakagaki K, Miura HS, Ami Y, Yamada YK, Itohara S, Holmes KV, Taguchi F
Journal of virology 2010 Jul;84(13):6654-66
Journal of virology 2010 Jul;84(13):6654-66
Skeletal muscle NAMPT is induced by exercise in humans.
Costford SR, Bajpeyi S, Pasarica M, Albarado DC, Thomas SC, Xie H, Church TS, Jubrias SA, Conley KE, Smith SR
American journal of physiology. Endocrinology and metabolism 2010 Jan;298(1):E117-26
American journal of physiology. Endocrinology and metabolism 2010 Jan;298(1):E117-26
Pannexin 2 is expressed by postnatal hippocampal neural progenitors and modulates neuronal commitment.
Swayne LA, Sorbara CD, Bennett SA
The Journal of biological chemistry 2010 Aug 6;285(32):24977-86
The Journal of biological chemistry 2010 Aug 6;285(32):24977-86
Arginase inhibition restores NOS coupling and reverses endothelial dysfunction and vascular stiffness in old rats.
Kim JH, Bugaj LJ, Oh YJ, Bivalacqua TJ, Ryoo S, Soucy KG, Santhanam L, Webb A, Camara A, Sikka G, Nyhan D, Shoukas AA, Ilies M, Christianson DW, Champion HC, Berkowitz DE
Journal of applied physiology (Bethesda, Md. : 1985) 2009 Oct;107(4):1249-57
Journal of applied physiology (Bethesda, Md. : 1985) 2009 Oct;107(4):1249-57
The proteasome is an integral part of solar ultraviolet a radiation-induced gene expression.
Catalgol B, Ziaja I, Breusing N, Jung T, Höhn A, Alpertunga B, Schroeder P, Chondrogianni N, Gonos ES, Petropoulos I, Friguet B, Klotz LO, Krutmann J, Grune T
The Journal of biological chemistry 2009 Oct 30;284(44):30076-86
The Journal of biological chemistry 2009 Oct 30;284(44):30076-86
Expression and activity of phosphodiesterase isoforms during epithelial mesenchymal transition: the role of phosphodiesterase 4.
Kolosionek E, Savai R, Ghofrani HA, Weissmann N, Guenther A, Grimminger F, Seeger W, Banat GA, Schermuly RT, Pullamsetti SS
Molecular biology of the cell 2009 Nov;20(22):4751-65
Molecular biology of the cell 2009 Nov;20(22):4751-65
Correlation of human leukocyte antigen-G (HLA-G) expression and disease progression in epithelial ovarian cancer.
Jung YW, Kim YT, Kim SW, Kim S, Kim JH, Cho NH, Kim JW
Reproductive sciences (Thousand Oaks, Calif.) 2009 Nov;16(11):1103-11
Reproductive sciences (Thousand Oaks, Calif.) 2009 Nov;16(11):1103-11
A UV-responsive internal ribosome entry site enhances serine hydroxymethyltransferase 1 expression for DNA damage repair.
Fox JT, Shin WK, Caudill MA, Stover PJ
The Journal of biological chemistry 2009 Nov 6;284(45):31097-108
The Journal of biological chemistry 2009 Nov 6;284(45):31097-108
Mechanism of the internal ribosome entry site-mediated translation of serine hydroxymethyltransferase 1.
Fox JT, Stover PJ
The Journal of biological chemistry 2009 Nov 6;284(45):31085-96
The Journal of biological chemistry 2009 Nov 6;284(45):31085-96
Clathrin-independent internalization of normal cellular prion protein in neuroblastoma cells is associated with the Arf6 pathway.
Kang YS, Zhao X, Lovaas J, Eisenberg E, Greene LE
Journal of cell science 2009 Nov 15;122(Pt 22):4062-9
Journal of cell science 2009 Nov 15;122(Pt 22):4062-9
A genome-scale RNAi screen for Oct4 modulators defines a role of the Paf1 complex for embryonic stem cell identity.
Ding L, Paszkowski-Rogacz M, Nitzsche A, Slabicki MM, Heninger AK, de Vries I, Kittler R, Junqueira M, Shevchenko A, Schulz H, Hubner N, Doss MX, Sachinidis A, Hescheler J, Iacone R, Anastassiadis K, Stewart AF, Pisabarro MT, Caldarelli A, Poser I, Theis M, Buchholz F
Cell stem cell 2009 May 8;4(5):403-15
Cell stem cell 2009 May 8;4(5):403-15
Interleukin-13-induced MUC5AC is regulated by 15-lipoxygenase 1 pathway in human bronchial epithelial cells.
Zhao J, Maskrey B, Balzar S, Chibana K, Mustovich A, Hu H, Trudeau JB, O'Donnell V, Wenzel SE
American journal of respiratory and critical care medicine 2009 May 1;179(9):782-90
American journal of respiratory and critical care medicine 2009 May 1;179(9):782-90
OSBP-related protein 2 is a sterol receptor on lipid droplets that regulates the metabolism of neutral lipids.
Hynynen R, Suchanek M, Spandl J, Bäck N, Thiele C, Olkkonen VM
Journal of lipid research 2009 Jul;50(7):1305-15
Journal of lipid research 2009 Jul;50(7):1305-15
Argininosuccinate synthetase is a functional target for a snake venom anti-hypertensive peptide: role in arginine and nitric oxide production.
Guerreiro JR, Lameu C, Oliveira EF, Klitzke CF, Melo RL, Linares E, Augusto O, Fox JW, Lebrun I, Serrano SM, Camargo AC
The Journal of biological chemistry 2009 Jul 24;284(30):20022-33
The Journal of biological chemistry 2009 Jul 24;284(30):20022-33
PARP-1 inhibits glycolysis in ischemic kidneys.
Devalaraja-Narashimha K, Padanilam BJ
Journal of the American Society of Nephrology : JASN 2009 Jan;20(1):95-103
Journal of the American Society of Nephrology : JASN 2009 Jan;20(1):95-103
Mthfd1 is an essential gene in mice and alters biomarkers of impaired one-carbon metabolism.
MacFarlane AJ, Perry CA, Girnary HH, Gao D, Allen RH, Stabler SP, Shane B, Stover PJ
The Journal of biological chemistry 2009 Jan 16;284(3):1533-9
The Journal of biological chemistry 2009 Jan 16;284(3):1533-9
The hemopexin domain of MMP-9 inhibits angiogenesis and retards the growth of intracranial glioblastoma xenograft in nude mice.
Ezhilarasan R, Jadhav U, Mohanam I, Rao JS, Gujrati M, Mohanam S
International journal of cancer 2009 Jan 15;124(2):306-15
International journal of cancer 2009 Jan 15;124(2):306-15
Migfilin interacts with Src and contributes to cell-matrix adhesion-mediated survival signaling.
Zhao J, Zhang Y, Ithychanda SS, Tu Y, Chen K, Qin J, Wu C
The Journal of biological chemistry 2009 Dec 4;284(49):34308-20
The Journal of biological chemistry 2009 Dec 4;284(49):34308-20
Crude subcellular fractionation of cultured mammalian cell lines.
Holden P, Horton WA
BMC research notes 2009 Dec 10;2:243
BMC research notes 2009 Dec 10;2:243
Intravesical combination treatment with antisense oligonucleotides targeting heat shock protein-27 and HTI-286 as a novel strategy for high-grade bladder cancer.
Matsui Y, Hadaschik BA, Fazli L, Andersen RJ, Gleave ME, So AI
Molecular cancer therapeutics 2009 Aug;8(8):2402-11
Molecular cancer therapeutics 2009 Aug;8(8):2402-11
Fumarate hydratase deficiency in renal cancer induces glycolytic addiction and hypoxia-inducible transcription factor 1alpha stabilization by glucose-dependent generation of reactive oxygen species.
Sudarshan S, Sourbier C, Kong HS, Block K, Valera Romero VA, Yang Y, Galindo C, Mollapour M, Scroggins B, Goode N, Lee MJ, Gourlay CW, Trepel J, Linehan WM, Neckers L
Molecular and cellular biology 2009 Aug;29(15):4080-90
Molecular and cellular biology 2009 Aug;29(15):4080-90
Transcriptional restriction of human immunodeficiency virus type 1 gene expression in undifferentiated primary monocytes.
Dong C, Kwas C, Wu L
Journal of virology 2009 Apr;83(8):3518-27
Journal of virology 2009 Apr;83(8):3518-27
A Golgi-associated protein 4.1B variant is required for assimilation of proteins in the membrane.
Kang Q, Wang T, Zhang H, Mohandas N, An X
Journal of cell science 2009 Apr 15;122(Pt 8):1091-9
Journal of cell science 2009 Apr 15;122(Pt 8):1091-9
Antileukemia effects of xanthohumol in Bcr/Abl-transformed cells involve nuclear factor-kappaB and p53 modulation.
Monteghirfo S, Tosetti F, Ambrosini C, Stigliani S, Pozzi S, Frassoni F, Fassina G, Soverini S, Albini A, Ferrari N
Molecular cancer therapeutics 2008 Sep;7(9):2692-702
Molecular cancer therapeutics 2008 Sep;7(9):2692-702
PTEN-deficient cancers depend on PIK3CB.
Wee S, Wiederschain D, Maira SM, Loo A, Miller C, deBeaumont R, Stegmeier F, Yao YM, Lengauer C
Proceedings of the National Academy of Sciences of the United States of America 2008 Sep 2;105(35):13057-62
Proceedings of the National Academy of Sciences of the United States of America 2008 Sep 2;105(35):13057-62
Glycogen synthase kinase 3beta regulates cell death induced by synthetic triterpenoids.
Venè R, Larghero P, Arena G, Sporn MB, Albini A, Tosetti F
Cancer research 2008 Sep 1;68(17):6987-96
Cancer research 2008 Sep 1;68(17):6987-96
The extensive nitration of neurofilament light chain in the hippocampus is associated with the cognitive impairment induced by amyloid beta in mice.
Alkam T, Nitta A, Mizoguchi H, Itoh A, Murai R, Nagai T, Yamada K, Nabeshima T
The Journal of pharmacology and experimental therapeutics 2008 Oct;327(1):137-47
The Journal of pharmacology and experimental therapeutics 2008 Oct;327(1):137-47
RNAi-mediated silencing of nuclear factor erythroid-2-related factor 2 gene expression in non-small cell lung cancer inhibits tumor growth and increases efficacy of chemotherapy.
Singh A, Boldin-Adamsky S, Thimmulappa RK, Rath SK, Ashush H, Coulter J, Blackford A, Goodman SN, Bunz F, Watson WH, Gabrielson E, Feinstein E, Biswal S
Cancer research 2008 Oct 1;68(19):7975-84
Cancer research 2008 Oct 1;68(19):7975-84
Combined tyrosine and serine/threonine kinase inhibition by sorafenib prevents progression of experimental pulmonary hypertension and myocardial remodeling.
Klein M, Schermuly RT, Ellinghaus P, Milting H, Riedl B, Nikolova S, Pullamsetti SS, Weissmann N, Dony E, Savai R, Ghofrani HA, Grimminger F, Busch AE, Schäfer S
Circulation 2008 Nov 11;118(20):2081-90
Circulation 2008 Nov 11;118(20):2081-90
Plakophilin 2: a critical scaffold for PKC alpha that regulates intercellular junction assembly.
Bass-Zubek AE, Hobbs RP, Amargo EV, Garcia NJ, Hsieh SN, Chen X, Wahl JK 3rd, Denning MF, Green KJ
The Journal of cell biology 2008 May 19;181(4):605-13
The Journal of cell biology 2008 May 19;181(4):605-13
Tempol protects against oxidative damage and delays epithelial tumor onset in Fanconi anemia mice.
Zhang QS, Eaton L, Snyder ER, Houghtaling S, Mitchell JB, Finegold M, Van Waes C, Grompe M
Cancer research 2008 Mar 1;68(5):1601-8
Cancer research 2008 Mar 1;68(5):1601-8
Signaling pathways modulated by fish oil in salt-sensitive hypertension.
Diaz Encarnacion MM, Warner GM, Gray CE, Cheng J, Keryakos HK, Nath KA, Grande JP
American journal of physiology. Renal physiology 2008 Jun;294(6):F1323-35
American journal of physiology. Renal physiology 2008 Jun;294(6):F1323-35
Tissue inhibitor of metalloproteinase 3 suppresses tumor angiogenesis in matrix metalloproteinase 2-down-regulated lung cancer.
Chetty C, Lakka SS, Bhoopathi P, Kunigal S, Geiss R, Rao JS
Cancer research 2008 Jun 15;68(12):4736-45
Cancer research 2008 Jun 15;68(12):4736-45
Metastatic susceptibility locus, an 8p hot-spot for tumour progression disrupted in colorectal liver metastases: 13 candidate genes examined at the DNA, mRNA and protein level.
Macartney-Coxson DP, Hood KA, Shi HJ, Ward T, Wiles A, O'Connor R, Hall DA, Lea RA, Royds JA, Stubbs RS, Rooker S
BMC cancer 2008 Jul 1;8:187
BMC cancer 2008 Jul 1;8:187
IL-1beta-driven ST2L expression promotes maturation resistance in rapamycin-conditioned dendritic cells.
Turnquist HR, Sumpter TL, Tsung A, Zahorchak AF, Nakao A, Nau GJ, Liew FY, Geller DA, Thomson AW
Journal of immunology (Baltimore, Md. : 1950) 2008 Jul 1;181(1):62-72
Journal of immunology (Baltimore, Md. : 1950) 2008 Jul 1;181(1):62-72
IL-1beta-driven ST2L expression promotes maturation resistance in rapamycin-conditioned dendritic cells.
Turnquist HR, Sumpter TL, Tsung A, Zahorchak AF, Nakao A, Nau GJ, Liew FY, Geller DA, Thomson AW
Journal of immunology (Baltimore, Md. : 1950) 2008 Jul 1;181(1):62-72
Journal of immunology (Baltimore, Md. : 1950) 2008 Jul 1;181(1):62-72
PINCH-1 regulates the ERK-Bim pathway and contributes to apoptosis resistance in cancer cells.
Chen K, Tu Y, Zhang Y, Blair HC, Zhang L, Wu C
The Journal of biological chemistry 2008 Feb 1;283(5):2508-17
The Journal of biological chemistry 2008 Feb 1;283(5):2508-17
Zag expression during aging suppresses proliferation after kidney injury.
Schmitt R, Marlier A, Cantley LG
Journal of the American Society of Nephrology : JASN 2008 Dec;19(12):2375-83
Journal of the American Society of Nephrology : JASN 2008 Dec;19(12):2375-83
The complement factor C5a contributes to pathology in a rat model of amyotrophic lateral sclerosis.
Woodruff TM, Costantini KJ, Crane JW, Atkin JD, Monk PN, Taylor SM, Noakes PG
Journal of immunology (Baltimore, Md. : 1950) 2008 Dec 15;181(12):8727-34
Journal of immunology (Baltimore, Md. : 1950) 2008 Dec 15;181(12):8727-34
The complement factor C5a contributes to pathology in a rat model of amyotrophic lateral sclerosis.
Woodruff TM, Costantini KJ, Crane JW, Atkin JD, Monk PN, Taylor SM, Noakes PG
Journal of immunology (Baltimore, Md. : 1950) 2008 Dec 15;181(12):8727-34
Journal of immunology (Baltimore, Md. : 1950) 2008 Dec 15;181(12):8727-34
uPAR promotes formation of the p130Cas-Crk complex to activate Rac through DOCK180.
Smith HW, Marra P, Marshall CJ
The Journal of cell biology 2008 Aug 25;182(4):777-90
The Journal of cell biology 2008 Aug 25;182(4):777-90
Cardiomyocyte apoptosis in autoimmune cardiomyopathy: mediated via endoplasmic reticulum stress and exaggerated by norepinephrine.
Mao W, Fukuoka S, Iwai C, Liu J, Sharma VK, Sheu SS, Fu M, Liang CS
American journal of physiology. Heart and circulatory physiology 2007 Sep;293(3):H1636-45
American journal of physiology. Heart and circulatory physiology 2007 Sep;293(3):H1636-45
CD200 and its receptor, CD200R, modulate bone mass via the differentiation of osteoclasts.
Cui W, Cuartas E, Ke J, Zhang Q, Einarsson HB, Sedgwick JD, Li J, Vignery A
Proceedings of the National Academy of Sciences of the United States of America 2007 Sep 4;104(36):14436-41
Proceedings of the National Academy of Sciences of the United States of America 2007 Sep 4;104(36):14436-41
Metformin transport by a newly cloned proton-stimulated organic cation transporter (plasma membrane monoamine transporter) expressed in human intestine.
Zhou M, Xia L, Wang J
Drug metabolism and disposition: the biological fate of chemicals 2007 Oct;35(10):1956-62
Drug metabolism and disposition: the biological fate of chemicals 2007 Oct;35(10):1956-62
A ferritin-responsive internal ribosome entry site regulates folate metabolism.
Woeller CF, Fox JT, Perry C, Stover PJ
The Journal of biological chemistry 2007 Oct 12;282(41):29927-35
The Journal of biological chemistry 2007 Oct 12;282(41):29927-35
Cdc42-interacting protein-4 functionally links actin and microtubule networks at the cytolytic NK cell immunological synapse.
Banerjee PP, Pandey R, Zheng R, Suhoski MM, Monaco-Shawver L, Orange JS
The Journal of experimental medicine 2007 Oct 1;204(10):2305-20
The Journal of experimental medicine 2007 Oct 1;204(10):2305-20
2-amino-N-{4-[5-(2-phenanthrenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-phenyl} acetamide (OSU-03012), a celecoxib derivative, directly targets p21-activated kinase.
Porchia LM, Guerra M, Wang YC, Zhang Y, Espinosa AV, Shinohara M, Kulp SK, Kirschner LS, Saji M, Chen CS, Ringel MD
Molecular pharmacology 2007 Nov;72(5):1124-31
Molecular pharmacology 2007 Nov;72(5):1124-31
Estrogen effects on skeletal muscle insulin-like growth factor 1 and myostatin in ovariectomized rats.
Tsai WJ, McCormick KM, Brazeau DA, Brazeau GA
Experimental biology and medicine (Maywood, N.J.) 2007 Nov;232(10):1314-25
Experimental biology and medicine (Maywood, N.J.) 2007 Nov;232(10):1314-25
NAD(P)H oxidases regulate HIF-2alpha protein expression.
Block K, Gorin Y, Hoover P, Williams P, Chelmicki T, Clark RA, Yoneda T, Abboud HE
The Journal of biological chemistry 2007 Mar 16;282(11):8019-26
The Journal of biological chemistry 2007 Mar 16;282(11):8019-26
Allelic variation in the hepatitis C virus NS4B protein dramatically influences RNA replication.
Blight KJ
Journal of virology 2007 Jun;81(11):5724-36
Journal of virology 2007 Jun;81(11):5724-36
Potentiation of insulin-stimulated glucose transport by the AMP-activated protein kinase.
Ju JS, Gitcho MA, Casmaer CA, Patil PB, Han DG, Spencer SA, Fisher JS
American journal of physiology. Cell physiology 2007 Jan;292(1):C564-72
American journal of physiology. Cell physiology 2007 Jan;292(1):C564-72
Membrane localization and pH-dependent transport of a newly cloned organic cation transporter (PMAT) in kidney cells.
Xia L, Engel K, Zhou M, Wang J
American journal of physiology. Renal physiology 2007 Feb;292(2):F682-90
American journal of physiology. Renal physiology 2007 Feb;292(2):F682-90
Apoptotic surge of potassium currents is mediated by p38 phosphorylation of Kv2.1.
Redman PT, He K, Hartnett KA, Jefferson BS, Hu L, Rosenberg PA, Levitan ES, Aizenman E
Proceedings of the National Academy of Sciences of the United States of America 2007 Feb 27;104(9):3568-73
Proceedings of the National Academy of Sciences of the United States of America 2007 Feb 27;104(9):3568-73
Increased insulin sensitivity and maintenance of glucose utilization rates in fetal sheep with placental insufficiency and intrauterine growth restriction.
Limesand SW, Rozance PJ, Smith D, Hay WW Jr
American journal of physiology. Endocrinology and metabolism 2007 Dec;293(6):E1716-25
American journal of physiology. Endocrinology and metabolism 2007 Dec;293(6):E1716-25
Heat-killed BCG induces biphasic cyclooxygenase 2+ splenic macrophage formation--role of IL-10 and bone marrow precursors.
Shibata Y, Gabbard J, Yamashita M, Tsuji S, Smith M, Nishiyama A, Henriksen RA, Myrvik QN
Journal of leukocyte biology 2006 Sep;80(3):590-8
Journal of leukocyte biology 2006 Sep;80(3):590-8
Activation of endoplasmic reticulum stress response during the development of ischemic heart disease.
Azfer A, Niu J, Rogers LM, Adamski FM, Kolattukudy PE
American journal of physiology. Heart and circulatory physiology 2006 Sep;291(3):H1411-20
American journal of physiology. Heart and circulatory physiology 2006 Sep;291(3):H1411-20
Pluronic L81 enhances triacylglycerol accumulation in the cytosol and inhibits chylomicron secretion.
Fatma S, Yakubov R, Anwar K, Hussain MM
Journal of lipid research 2006 Nov;47(11):2422-32
Journal of lipid research 2006 Nov;47(11):2422-32
Dimethyl sulfoxide has an impact on epigenetic profile in mouse embryoid body.
Iwatani M, Ikegami K, Kremenska Y, Hattori N, Tanaka S, Yagi S, Shiota K
Stem cells (Dayton, Ohio) 2006 Nov;24(11):2549-56
Stem cells (Dayton, Ohio) 2006 Nov;24(11):2549-56
Developmental changes in ovine myocardial glucose transporters and insulin signaling following hyperthermia-induced intrauterine fetal growth restriction.
Barry JS, Davidsen ML, Limesand SW, Galan HL, Friedman JE, Regnault TR, Hay WW Jr
Experimental biology and medicine (Maywood, N.J.) 2006 May;231(5):566-75
Experimental biology and medicine (Maywood, N.J.) 2006 May;231(5):566-75
Developmental changes in ovine myocardial glucose transporters and insulin signaling following hyperthermia-induced intrauterine fetal growth restriction.
Barry JS, Davidsen ML, Limesand SW, Galan HL, Friedman JE, Regnault TR, Hay WW Jr
Experimental biology and medicine (Maywood, N.J.) 2006 May;231(5):566-75
Experimental biology and medicine (Maywood, N.J.) 2006 May;231(5):566-75
Mitogen-activated protein kinases control cardiac KChIP2 gene expression.
Jia Y, Takimoto K
Circulation research 2006 Feb 17;98(3):386-93
Circulation research 2006 Feb 17;98(3):386-93
The differentiation-dependent desmosomal cadherin desmoglein 1 is a novel caspase-3 target that regulates apoptosis in keratinocytes.
Dusek RL, Getsios S, Chen F, Park JK, Amargo EV, Cryns VL, Green KJ
The Journal of biological chemistry 2006 Feb 10;281(6):3614-24
The Journal of biological chemistry 2006 Feb 10;281(6):3614-24
Phosphorylation of focal adhesion kinase (FAK) on Ser732 is induced by rho-dependent kinase and is essential for proline-rich tyrosine kinase-2-mediated phosphorylation of FAK on Tyr407 in response to vascular endothelial growth factor.
Le Boeuf F, Houle F, Sussman M, Huot J
Molecular biology of the cell 2006 Aug;17(8):3508-20
Molecular biology of the cell 2006 Aug;17(8):3508-20
Automated quantification tool for high-throughput proteomics using stable isotope labeling and LC-MSn.
Wang G, Wu WW, Pisitkun T, Hoffert JD, Knepper MA, Shen RF
Analytical chemistry 2006 Aug 15;78(16):5752-61
Analytical chemistry 2006 Aug 15;78(16):5752-61
Reversal of RNA missplicing and myotonia after muscleblind overexpression in a mouse poly(CUG) model for myotonic dystrophy.
Kanadia RN, Shin J, Yuan Y, Beattie SG, Wheeler TM, Thornton CA, Swanson MS
Proceedings of the National Academy of Sciences of the United States of America 2006 Aug 1;103(31):11748-53
Proceedings of the National Academy of Sciences of the United States of America 2006 Aug 1;103(31):11748-53
Inhibition of apoptosis by P2Y2 receptor activation: novel pathways for neuronal survival.
Arthur DB, Georgi S, Akassoglou K, Insel PA
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006 Apr 5;26(14):3798-804
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006 Apr 5;26(14):3798-804
High-throughput identification of IMCD proteins using LC-MS/MS.
Pisitkun T, Bieniek J, Tchapyjnikov D, Wang G, Wu WW, Shen RF, Knepper MA
Physiological genomics 2006 Apr 13;25(2):263-76
Physiological genomics 2006 Apr 13;25(2):263-76
Increased susceptibility to transcriptional changes with novel stressor in adrenal medulla of rats exposed to prolonged cold stress.
Liu X, Kvetnansky R, Serova L, Sollas A, Sabban EL
Brain research. Molecular brain research 2005 Nov 18;141(1):19-29
Brain research. Molecular brain research 2005 Nov 18;141(1):19-29
Regulation of endothelial argininosuccinate synthase expression and NO production by an upstream open reading frame.
Pendleton LC, Goodwin BL, Solomonson LP, Eichler DC
The Journal of biological chemistry 2005 Jun 24;280(25):24252-60
The Journal of biological chemistry 2005 Jun 24;280(25):24252-60
Desmoplakin assembly dynamics in four dimensions: multiple phases differentially regulated by intermediate filaments and actin.
Godsel LM, Hsieh SN, Amargo EV, Bass AE, Pascoe-McGillicuddy LT, Huen AC, Thorne ME, Gaudry CA, Park JK, Myung K, Goldman RD, Chew TL, Green KJ
The Journal of cell biology 2005 Dec 19;171(6):1045-59
The Journal of cell biology 2005 Dec 19;171(6):1045-59
Differential regulation of the cell cycle by alpha1-adrenergic receptor subtypes.
Gonzalez-Cabrera PJ, Shi T, Yun J, McCune DF, Rorabaugh BR, Perez DM
Endocrinology 2004 Nov;145(11):5157-67
Endocrinology 2004 Nov;145(11):5157-67
Prognostic significance of a short sequence insertion in the MCL-1 promoter in chronic lymphocytic leukemia.
Moshynska O, Sankaran K, Pahwa P, Saxena A
Journal of the National Cancer Institute 2004 May 5;96(9):673-82
Journal of the National Cancer Institute 2004 May 5;96(9):673-82
Prognostic significance of a short sequence insertion in the MCL-1 promoter in chronic lymphocytic leukemia.
Moshynska O, Sankaran K, Pahwa P, Saxena A
Journal of the National Cancer Institute 2004 May 5;96(9):673-82
Journal of the National Cancer Institute 2004 May 5;96(9):673-82
Cathepsin B mRNA and protein expression following contusion spinal cord injury in rats.
Ellis RC, Earnhardt JN, Hayes RL, Wang KK, Anderson DK
Journal of neurochemistry 2004 Feb;88(3):689-97
Journal of neurochemistry 2004 Feb;88(3):689-97
Cathepsin B mRNA and protein expression following contusion spinal cord injury in rats.
Ellis RC, Earnhardt JN, Hayes RL, Wang KK, Anderson DK
Journal of neurochemistry 2004 Feb;88(3):689-97
Journal of neurochemistry 2004 Feb;88(3):689-97
Myocardial cell death and regeneration during progression of cardiac hypertrophy to heart failure.
Sarkar S, Chawla-Sarkar M, Young D, Nishiyama K, Rayborn ME, Hollyfield JG, Sen S
The Journal of biological chemistry 2004 Dec 10;279(50):52630-42
The Journal of biological chemistry 2004 Dec 10;279(50):52630-42
Brain-specific deletion of neuropathy target esterase/swisscheese results in neurodegeneration.
Akassoglou K, Malester B, Xu J, Tessarollo L, Rosenbluth J, Chao MV
Proceedings of the National Academy of Sciences of the United States of America 2004 Apr 6;101(14):5075-80
Proceedings of the National Academy of Sciences of the United States of America 2004 Apr 6;101(14):5075-80
Emerging role for autophagy in the removal of aggresomes in Schwann cells.
Fortun J, Dunn WA Jr, Joy S, Li J, Notterpek L
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003 Nov 19;23(33):10672-80
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003 Nov 19;23(33):10672-80
Interference of hepatitis C virus RNA replication by short interfering RNAs.
Kapadia SB, Brideau-Andersen A, Chisari FV
Proceedings of the National Academy of Sciences of the United States of America 2003 Feb 18;100(4):2014-8
Proceedings of the National Academy of Sciences of the United States of America 2003 Feb 18;100(4):2014-8
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- Western Blot: GAPDH Antibody (1D4) [NB300-221] - analysis of GAPDH in chicken pectoralis major using anti-GAPDH antibody. The primary antibody was used at a dilution of 1:4000, incubated for 1 hour at room temperature. Western blot image submitted by a verified customer review.
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- Western Blot: GAPDH Antibody (1D4) [NB300-221] - analysis of GAPDH in human nucleus pulposus cell culture (40ug/lane) using anti-GAPDH antibody. LI-COR Odyssey imaging system was used for detection. Western blot image submitted by a verified customer review.
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- Western Blot: GAPDH Antibody (1D4) [NB300-221] - Analysis of cell line lysates probed with mouse mAb to GAPDH (theoretical molecular weight: 36 kDa), NB300-221, dilution 1:2,000: [1] protein standard, [2] HEK293, [3] HeLa, [4] SH-SY5Y, [5] COS1, [6] NIH-3T3, and [7] C6 cells. The GAPDH antibody reveals a single band at ~37 kDa in all cell lines. GAPDH is a house keeping protein, the level of which is relatively unaffected by most experimental manipulations, and, as a result, this antibody has been widely used as a western blotting loading control.
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- Simple Western: GAPDH Antibody (1D4) [NB300-221] - Lane view shows a specific band for GAPDH using 0.05 mg/mL Jurkat and MCF-7 cell lysates and antibody at 1:25. Electropherogram image of corresponding Simple Western lanes view at WES molecular weight of 40 kDa. Image reported by internal validation.
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- Western Blot: GAPDH Antibody (1D4) [NB300-221] - Regulation of cell migration-associated proteins by NCKU-21 in A549 and CL1-5 cells. Protein expressions of matrix metalloproteinase-2 (MMP-2) and MMP-9 were analyzed in A549 cell treated with NCKU-21 for 24 hr. * P < 0.05 and ** P < 0.01, compared to the control group (without NCKU-21 treatment). Image collected and cropped by CiteAb from the following publication (https://dx.plos.org/10.1371/journal.pone.0185021), licensed under a CC-BY licence.
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- Western Blot: GAPDH Antibody (1D4) [NB300-221] - FerrylHb induces HO-1 and ferritin in EC. Confluent HUVECs grown on 6-well plates were exposed to heme, Hb, metHb, and ferrylHb (100 umol/L heme or as indicated in complete medium containing 15% of FBS). After 4 hours of incubation total RNA was isolated and HO-1 mRNA level was measured by quantitative RT-PCR. For protein expression, HUVECs were solubilized after 8 hours of treatment. HO-1 and ferritin H and L expression was detected by Western blot. Immunoblots were reprobed with GAPDH and are representative of three independent experiments. Results are shown as mean +/- S.D. (n = 3) from one representative experiment of three. Image collected and cropped by CiteAb from the following publication (http://www.hindawi.com/journals/omcl/2013/676425/), licensed under a CC-BY licence.
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- Western Blot: GAPDH Antibody (1D4) [NB300-221] - Endothelial responses provoked by Hb-lipid interactions are attenuated by sulfide donors. Confluence HAoECs were exposed to the obtained Hb samples for 8 hours and VCAM-1 expression was determined by Western blotting. GAPDH were used as a loading control. Representative experiment, n = 3. Image collected and cropped by CiteAb from the following publication (https://www.hindawi.com/journals/omcl/2018/3812568/), licensed under a CC-BY licence.
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- Western Blot: GAPDH Antibody (1D4) [NB300-221] - Application of the approach to other cell lines. The remainder of the protocol from Figure 2 was then applied using 100 ug/mL digitonin as the optimal cytosolic extract in each case. An aliquot of each extract was then analyzed by 4-12% SDS PAGE followed by Western blotting and probing with antibodies to GAPDH, BiP and Histone H3 (Used as an alternative nuclear marker due to weakness of the Lamin A signal in HeLa cells). Image collected and cropped by CiteAb from the following publication (http://bmcresnotes.biomedcentral.com/articles/10.1186/1756-0500-2-243) licensed under a CC-BY licence.