BS7142

antibody from Bioworld Technology, Inc
Targeting: IL16 FLJ16806, FLJ42735, HsT19289, IL-16, LCF, prIL-16
Provider product page for BS7142
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS7142 - Provider product page
Provider
Bioworld Technology, Inc
Product name
IL 16 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human IL-16.
Description
Originally known as lymphocyte chemoattractant factor (LCF), Interleukin-16 (IL-16) is a product of human peripheral mononuclear cells when antigen-stimulated or mitogen-stimulated. It is also produced by dendritic cells, epithelial cells, eosinophils, fibroblasts and mast cells. The pro-form of IL-16 is a 631 amino acid protein that is cleaved by caspase 3 in activated CD4+ T cells where it is then secreted and is accessible for binding CD4 receptors. IL-16 regulates and induces migratory response in CD4+ lymphocytes, eosinophils, and monocytes. It is a soluble ligand for CD4 and functions to prime responsiveness to IL-2 and IL-15 in CD4+ T-cells. Although Isoform 1£ªs function is thought to be as an anchor to membrane ion channels, Isoform 3 is more widely researched and characterized as component of T-cell cycle progression.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
IL16 protein structure - BS7142 shown in red.