abx002355

antibody from Abbexa

Targeting: NR3C2 MLR, MR

Western blot (Recommended by provider)

Antibody Data

Product number

abx002355

Provider

Abbexa

Product name

Mineralocorticoid Receptor (NR3C2) Antibody

Antibody type

Polyclonal

Description

NR3C2 Antibody is a Rabbit Polyclonal antibody against NR3C2. This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

> 1 mg/ml

Storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.