BS1908

antibody from Bioworld Technology, Inc

Targeting: TOP3B

Immunohistochemistry

Antibody data

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Validation data

Product number: BS1908 - Provider product page
Provider: Bioworld Technology, Inc
Proper citation: Bioworld Technology Cat#BS1908, RRID:AB_1663070
Product name: Topo IIIÉÇ 1 (Q84) polyclonal antibody
Antibody type: Polyclonal
Antigen: Synthetic peptide, corresponding to amino acids 51-100 of Human Topo IIIÉÇ-1.
Description: DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA by transiently breaking and rejoining DNA strands. Although DNA topoisomerase I and DNA topoisomerase II relax both positive and negative supercoils, DNA topoisomerase III relaxes only negative supercoils. DNA topoisomerase III Ï« exists as a long and a short isoform, which are produced by alternative splicing. DNA topoisomerase III Ï«, which localizes to the nucleolus, is constitutively expressed and remains at high levels throughout the cell cycle in HL-60 cells. DNA topoisomerase III ÉÇ exists as three isoforms, namely ÉÇ1, ÉÇ2 and ÉÇ3, also produced by alternative splicing. DNA topoisomerase III ÉÇ1 is expressed in testes, heart and skeletal muscle, whereas ÉÇ2 is expressed in thymus, kidney and pancreas.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Vial size: 100ul
Concentration: 1 mg/ml
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

TOP3B protein structure - BS1908 shown in red.